Detailed information for compound 321159

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 328.977 | Formula: C4H11BrO8P2
  • H donors: 4 H acceptors: 6 LogP: -2.15 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: BrC[C@@H](CCOP(=O)(OP(=O)(O)O)O)O
  • InChi: 1S/C4H11BrO8P2/c5-3-4(6)1-2-12-15(10,11)13-14(7,8)9/h4,6H,1-3H2,(H,10,11)(H2,7,8,9)/t4-/m1/s1
  • InChiKey: VAKJGTVWZROYEC-SCSAIBSYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0439 0.1669 0.1886
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0047 0.0105 0.0109
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0023 0.0281
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0002 0.0004
Echinococcus granulosus g protein coupled receptor 0.0181 0.0642 0.0642
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0023 0.0015
Trichomonas vaginalis pyruvate kinase, putative 0.0224 0.0812 0.081
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.026 0.0956 0.0954
Schistosoma mansoni ribokinase 0.0156 0.0542 0.1005
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0021
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0058 0.0693
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0154 0.0259
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0237 0.2897
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Brugia malayi AKH receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0023 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.0642 0.0642
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0077 0.0075
Echinococcus granulosus biogenic amine 5HT receptor 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.033 0.1236 0.1236
Echinococcus multilocularis adenosine kinase 0.1371 0.5391 0.5391
Brugia malayi PAS domain containing protein 0.0101 0.0322 0.0322
Onchocerca volvulus 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0054 0.0099
Brugia malayi hypothetical protein 0.0265 0.0975 0.0975
Schistosoma mansoni biogenic amine receptor 0.0181 0.0642 0.1191
Loa Loa (eye worm) 6-phosphofructokinase 0.0219 0.0792 0.0792
Mycobacterium leprae Probable adenosine kinase adk 0.0156 0.0542 0.6663
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0181 0.0642 0.0642
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0382 0.1442 0.2674
Brugia malayi Cytochrome P450 family protein 0.0032 0.0046 0.0046
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2227 0.8808 0.8808
Echinococcus granulosus neurogenic locus notch protein 4 0.0086 0.026 0.026
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0439 0.1669 0.1886
Plasmodium falciparum thioredoxin reductase 0.0049 0.0115 0.1411
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0468 0.0521
Leishmania major pyruvate kinase 0.0224 0.0812 0.0912
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0076 0.0223 0.0223
Echinococcus granulosus lysosomal alpha glucosidase 0.018 0.0635 0.0635
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Schistosoma mansoni amine GPCR 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Schistosoma mansoni 6-phosphofructokinase 0.0219 0.0792 0.147
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0181 0.0642 0.1191
Leishmania major nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Toxoplasma gondii kinase, pfkB family protein 0.1371 0.5391 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0262 0.0459
Echinococcus granulosus neuropeptide s receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.2526 1 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0382 0.1442 0.1628
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0382 0.1442 0.144
Onchocerca volvulus Chorion peroxidase homolog 0.0265 0.0975 0.0975
Trypanosoma brucei adenosine kinase, putative 0.1371 0.5391 0.6117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0042 0.0078
Loa Loa (eye worm) hypothetical protein 0.0054 0.0133 0.0133
Trypanosoma brucei ribokinase, putative 0.0156 0.0542 0.0605
Brugia malayi Cytochrome P450 family protein 0.0032 0.0046 0.0046
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0131 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0023 0.0021
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.0645
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0047 0.0105 0.0109
Schistosoma mansoni lipoxygenase 0.0057 0.0147 0.0274
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0023 0.0021
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0087 0.0265 0.0291
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0033 0.0033
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0382 0.1442 0.144
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0023 0.0021
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0094 0.0094
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.1298
Trichomonas vaginalis pyruvate kinase, putative 0.0224 0.0812 0.081
Loa Loa (eye worm) hypothetical protein 0.0145 0.0499 0.0499
Schistosoma mansoni neuropeptide receptor 0.0181 0.0642 0.1191
Trypanosoma brucei adenosine transporter, putative 0.0439 0.1669 0.1886
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0047 0.0105 0.1298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.026 0.0956 0.0954
Echinococcus granulosus neuropeptide receptor A26 0.0181 0.0642 0.0642
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0147 0.0147
Echinococcus multilocularis peroxidasin 0.0265 0.0975 0.0975
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0002 0.0002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0154 0.0152
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.1298
Mycobacterium ulcerans putative regulatory protein 0.0122 0.0404 0.4957
Giardia lamblia Kinase, PLK 0.0092 0.0284 0.0181
Brugia malayi Delta serrate ligand family protein 0.0086 0.026 0.026
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1634 0.644 0.644
Echinococcus multilocularis bloom syndrome protein 0.0043 0.009 0.009
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0023 0.0023
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0182 0.0645 0.0645
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0468 0.0521
Schistosoma mansoni kinase 0.0047 0.0105 0.0195
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.3228
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0104 0.0333 0.0333
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0077 0.0075
Schistosoma mansoni neuropeptide f receptor 76f 0.0181 0.0642 0.1191
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Brugia malayi neuropeptide F receptor 0.0181 0.0642 0.0642
Leishmania major protein kinase, putative 0.0027 0.0026 0.0019
Mycobacterium leprae Probable pyruvate kinase PykA 0.0224 0.0812 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0144 0.175
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0015 0.0165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0284 0.0284
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Mycobacterium ulcerans pyruvate kinase 0.0224 0.0812 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0169 0.0591 0.0591
Brugia malayi intermediate filament protein 0.0054 0.0135 0.0135
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.0642 0.0642
Plasmodium vivax SET domain protein, putative 0.0031 0.0042 0.0519
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.0642 0.0642
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0542 0.0539
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0169 0.0591 0.0591
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0071 0.0071
Brugia malayi GCC2 and GCC3 family protein 0.0086 0.026 0.026
Leishmania major hypothetical protein, conserved 0.0047 0.0105 0.0109
Brugia malayi pyruvate kinase, muscle isozyme 0.0047 0.0106 0.0106
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0131 0.0138
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) animal heme peroxidase 0.0265 0.0975 0.0975
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0366 0.4497
Onchocerca volvulus 0.0181 0.0642 0.0642
Loa Loa (eye worm) animal heme peroxidase 0.0265 0.0975 0.0975
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0058 0.0055
Brugia malayi Animal haem peroxidase family protein 0.0265 0.0975 0.0975
Trypanosoma brucei nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0023 0.0021
Trichomonas vaginalis esterase, putative 0.0035 0.0058 0.0056
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus granulosus bloom syndrome protein 0.0043 0.009 0.009
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Brugia malayi Blistered cuticle protein 3 0.0265 0.0975 0.0975
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0026 0.0019
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0131 0.0215
Brugia malayi Dopamine receptor protein 1 0.0181 0.0642 0.0642
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0181 0.0642 0.0642
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0015 0.0165
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0071 0.0071
Brugia malayi hypothetical protein 0.0038 0.0071 0.0071
Echinococcus granulosus intermediate filament protein 0.0054 0.0135 0.0135
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0262 0.0486
Loa Loa (eye worm) hypothetical protein 0.1073 0.4201 0.4201
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus Slit protein homolog 0.0086 0.026 0.026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Echinococcus granulosus pyruvate kinase 0.0115 0.0377 0.0377
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0076 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.008 0.0237 0.0237
Leishmania major putative PfkB family sugar kinase 0.0156 0.0542 0.0605
Loa Loa (eye worm) 6-phosphofructokinase 0.0219 0.0792 0.0792
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni patched 1 0.0044 0.0094 0.0174
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0642 0.0642
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0181 0.0642 0.0642
Brugia malayi hypothetical protein 0.0076 0.0223 0.0223
Onchocerca volvulus Neurogenic locus notch homolog 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Echinococcus multilocularis protein jagged 2 0.0086 0.026 0.026
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0002 0.0004
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0439 0.1669 0.1886
Echinococcus multilocularis pyruvate kinase 0.0115 0.0377 0.0377
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0076 0.0223 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Loa Loa (eye worm) hypothetical protein 0.1138 0.4462 0.4462
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0058 0.0694
Echinococcus granulosus sex peptide receptor 0.0181 0.0642 0.0642
Echinococcus granulosus pyruvate kinase 0.0115 0.0377 0.0377
Echinococcus granulosus neuropeptide receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis transfer RNA-Lys 0.0075 0.0217 0.0217
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0002 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Echinococcus multilocularis protein jagged 1 0.0086 0.026 0.026
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0439 0.1669 0.1886
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0002 0.0002
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0382 0.1442 0.1442
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0023 0.0021
Schistosoma mansoni hypothetical protein 0.0038 0.0071 0.0131
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0047 0.0105 0.0105
Toxoplasma gondii hypothetical protein 0.0122 0.0404 0.0722
Onchocerca volvulus 0.0133 0.045 0.045
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0002 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0002 0.0004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus multilocularis fmrfamide receptor 0.0181 0.0642 0.0642
Echinococcus granulosus protein jagged 2 0.0086 0.026 0.026
Onchocerca volvulus 0.0181 0.0642 0.0642
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0237 0.2897
Echinococcus multilocularis G-protein coupled receptor, putative 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypoxia-induced factor 1 0.0313 0.1169 0.1169
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.0642 0.0642
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0058 0.0056
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0023 0.0023
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0154 0.0259
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0058 0.0693
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0105
Echinococcus multilocularis protein dispatched 1 0.005 0.0118 0.0118
Leishmania major hypothetical protein, conserved 0.0035 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0047 0.0105 0.0105
Schistosoma mansoni notch 0.0086 0.026 0.0482
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0262 0.0459
Echinococcus multilocularis neuropeptide receptor A26 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.0327 0.0327
Onchocerca volvulus 0.0156 0.0542 0.0542
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.01 0.0098
Loa Loa (eye worm) hypothetical protein 0.0057 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0145 0.0499 0.0499
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0181 0.0642 0.0642
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0094 0.0094
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0154 0.19
Loa Loa (eye worm) hypothetical protein 0.1073 0.4201 0.4201
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.0642 0.0642
Schistosoma mansoni laminin gamma-3 chain 0.0086 0.026 0.0481
Schistosoma mansoni pyruvate kinase 0.0224 0.0812 0.1506
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.3098
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0086 0.026 0.0481
Schistosoma mansoni sodium/chloride dependent transporter 0.0183 0.0648 0.1202
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.026 0.0956 0.1076
Onchocerca volvulus 0.0133 0.045 0.045
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.009 0.009
Plasmodium falciparum pyruvate kinase 0.0224 0.0812 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0086 0.026 0.026
Echinococcus multilocularis notch 0.0086 0.026 0.026
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0047 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Onchocerca volvulus Peroxidase homolog 0.0265 0.0975 0.0975
Brugia malayi Animal haem peroxidase family protein 0.0265 0.0975 0.0975
Trichomonas vaginalis ribokinase, putative 0.0156 0.0542 0.0539
Entamoeba histolytica hypothetical protein 0.0038 0.0071 0.0068
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0047 0.0105 0.0109
Brugia malayi hypothetical protein 0.0021 0.0002 0.0002
Onchocerca volvulus 0.0181 0.0642 0.0642
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0642 0.1191
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0069 0.0848
Loa Loa (eye worm) hypothetical protein 0.0156 0.0542 0.0542
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0023
Entamoeba histolytica nucleoside transporter, putative 0.0439 0.1669 0.1667
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0077 0.0077
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.034 0.1275 0.1275
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0122 0.0404 0.4956
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.0642 0.1191
Echinococcus multilocularis ribokinase 0.0156 0.0542 0.0542
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0156 0.0542 0.0539
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0042 0.0078
Brugia malayi GnHR receptor homolog 0.0181 0.0642 0.0642
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1073 0.4201 0.4201
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0439 0.1669 0.1886
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0047 0.0105 0.0195
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0181 0.0642 0.0642
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0077 0.0075
Brugia malayi beta-lactamase family protein 0.0035 0.0058 0.0058
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0264 0.0264
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0002 0.0002
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0047 0.0105 0.0105
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0262 0.0262
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0181 0.0642 0.0642
Echinococcus multilocularis dro:myosuppressin receptor 0.0181 0.0642 0.0642
Toxoplasma gondii endonuclease IV APN 0.008 0.0237 0.0412
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Schistosoma mansoni notch 0.0086 0.026 0.0481
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0047 0.0105 0.0105
Schistosoma mansoni lamin 0.0054 0.0135 0.025
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0047 0.0105 0.0109
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2526 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0058 0.0693
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Onchocerca volvulus 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Echinococcus granulosus biogenic amine 5HT receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0002 0.0002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0262 0.3228
Brugia malayi G-protein coupled receptor 0.0181 0.0642 0.0642
Entamoeba histolytica nucleoside transporter, putative 0.2526 1 1
Echinococcus multilocularis lamin dm0 0.0054 0.0135 0.0135
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0061 0.0747
Toxoplasma gondii pyruvate kinase PyK1 0.0224 0.0812 0.1482
Leishmania major cAMP-specific phosphodiesterase, putative 0.0047 0.0105 0.0109
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0439 0.1669 0.1667
Chlamydia trachomatis endonuclease IV 0.008 0.0237 0.2778
Schistosoma mansoni adenoreceptor 0.0181 0.0642 0.1191
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0181 0.0642 0.1191
Brugia malayi putative neuropeptide receptor 0.0181 0.0642 0.0642
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0334 0.0619
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trypanosoma brucei hypothetical protein, conserved 0.0047 0.0105 0.0109
Brugia malayi Thioredoxin reductase 0.0049 0.0115 0.0115
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0002 0.0002
Onchocerca volvulus Putative pyridoxal kinase 0.0156 0.0542 0.0542
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0002 0.0002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0181 0.0642 0.1191
Trypanosoma brucei adenosine transporter 2 0.0439 0.1669 0.1886
Echinococcus multilocularis g-protein coupled receptor 0.0181 0.0642 0.0642
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2526 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0181 0.0642 0.0642
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0002 0.0002
Trypanosoma brucei adenosine transporter 2, putative 0.0439 0.1669 0.1886
Trypanosoma brucei unspecified product 0.0439 0.1669 0.1886
Schistosoma mansoni single-minded 0.0101 0.0322 0.0598
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0058 0.0058
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0156 0.0542 0.0542
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0145 0.0143
Schistosoma mansoni alpha-glucosidase 0.0155 0.0535 0.0992
Brugia malayi hypothetical protein 0.0026 0.0023 0.0023
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0439 0.1669 0.1667
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Mycobacterium ulcerans 6-phosphofructokinase 0.0219 0.0792 0.9756
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0439 0.1669 0.1667
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0076 0.0223 0.0223
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0002 0.0002
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Mycobacterium tuberculosis Conserved protein 0.0035 0.0058 0.0693
Loa Loa (eye worm) hypothetical protein 0.0076 0.0223 0.0223
Trichomonas vaginalis phosphofructokinase, putative 0.0219 0.0792 0.079
Trypanosoma brucei polo-like protein kinase 0.0092 0.0284 0.0312
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0042 0.0042
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1073 0.4201 0.7792
Echinococcus granulosus equilibrative nucleoside transporter 3 0.2526 1 1
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0002 0.0002
Brugia malayi CHE-14 protein 0.0044 0.0094 0.0094
Mycobacterium leprae Possible regulatory protein 0.0026 0.0023 0.0263
Onchocerca volvulus 0.0086 0.026 0.026
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni pyruvate kinase 0.0115 0.0377 0.0699
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0135 0.0135
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0034 0.0034
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.1298
Onchocerca volvulus Dual oxidase homolog 0.0265 0.0975 0.0975
Plasmodium vivax glutathione reductase, putative 0.0049 0.0115 0.1411
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Plasmodium falciparum phosphodiesterase gamma, putative 0.0047 0.0105 0.1298
Loa Loa (eye worm) solute carrier family 6 member 4 0.1073 0.4201 0.4201
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0002 0.0004
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0002 0.0002
Echinococcus multilocularis muscleblind protein 0.0145 0.0499 0.0499
Onchocerca volvulus 0.0054 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Echinococcus multilocularis neuropeptide receptor 0.0181 0.0642 0.0642
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0002 0.0002
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0037 0.0429
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0181 0.0642 0.0642
Brugia malayi Cadherin domain containing protein 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Echinococcus granulosus neurogenic locus protein delta 0.0086 0.026 0.026
Entamoeba histolytica ribokinase, putative 0.0156 0.0542 0.0539
Trypanosoma brucei adenosine transporter 2 0.0439 0.1669 0.1886
Schistosoma mansoni protein kinase 0.0439 0.1672 0.3101
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Brugia malayi MAP kinase sur-1 0.0053 0.0131 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0642 0.1191
Mycobacterium tuberculosis Probable reductase 0.0112 0.0366 0.4497
Entamoeba histolytica recQ family helicase, putative 0.0023 0.001 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.018 0.0635 0.0635
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.0642 0.0642
Trypanosoma cruzi nucleoside transporter-like, putative 0.0439 0.1669 0.1886
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0181 0.0642 0.1191
Brugia malayi hypothetical protein 0.0057 0.0145 0.0145
Brugia malayi putative neuropeptide receptor NPR1 0.0181 0.0642 0.0642
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0103
Onchocerca volvulus 0.0181 0.0642 0.0642
Brugia malayi G-protein coupled receptor 0.0181 0.0642 0.0642
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0264 0.0489
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.0642 0.0642
Trichomonas vaginalis ribokinase, putative 0.0156 0.0542 0.0539
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.0642 0.0642
Trypanosoma cruzi adenosine kinase, putative 0.1371 0.5391 0.6117
Brugia malayi Dopamine receptor protein 2 0.0181 0.0642 0.0642
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0037 0.0051
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.01 0.0316 0.0316
Echinococcus multilocularis pyruvate kinase 0.0177 0.0624 0.0624
Echinococcus multilocularis neurogenic locus protein delta 0.0086 0.026 0.026
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Loa Loa (eye worm) hypothetical protein 0.0054 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi beta-lactamase family protein 0.0035 0.0058 0.0058
Onchocerca volvulus 0.0181 0.0642 0.0642
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0144 0.0144
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0058 0.0694
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0061 0.0058
Schistosoma mansoni myosin xvIII 0.0181 0.0642 0.1191
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.3213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Echinococcus granulosus protein jagged 1 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Echinococcus granulosus allatostatin A receptor 0.0181 0.0642 0.0642
Onchocerca volvulus 0.1215 0.4768 0.4768
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) glutathione reductase 0.0049 0.0115 0.0115
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0645 0.1197
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0023 0.0015
Toxoplasma gondii RNA-directed DNA polymerase 0.0087 0.0265 0.0465
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.0901 0.0901
Leishmania major hypothetical protein, conserved 0.0036 0.0061 0.0058
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0783 0.0783
Brugia malayi Cytochrome P450 family protein 0.0034 0.0055 0.0055
Brugia malayi Probable ClpP-like protease 0.0086 0.0262 0.0262
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0144 0.1749
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0131 0.0129
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0181 0.0642 0.0642
Onchocerca volvulus Ribokinase homolog 0.0156 0.0542 0.0542
Leishmania major hypothetical protein, conserved 0.0026 0.0023 0.0015
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0015 0.0188
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.0327 0.0327
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0122 0.0404 0.4957
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni hypothetical protein 0.0042 0.0087 0.0162
Onchocerca volvulus 0.01 0.0316 0.0316
Echinococcus granulosus orexin receptor type 2 0.0181 0.0642 0.0642
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Toxoplasma gondii GAF domain-containing protein 0.0122 0.0404 0.0722
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi pyruvate kinase 0.0047 0.0106 0.0106
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0002 0.0004
Trypanosoma brucei trypanothione reductase 0.0049 0.0115 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0058 0.0108
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Mycobacterium tuberculosis Ribokinase RbsK 0.0156 0.0542 0.6661
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0006 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.2526 1 1
Echinococcus multilocularis lamin 0.0054 0.0135 0.0135
Echinococcus granulosus g protein coupled receptor 0.0181 0.0642 0.0642
Echinococcus granulosus neuropeptide receptor 0.0181 0.0642 0.0642
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.059
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus 0.005 0.0119 0.0119
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Schistosoma mansoni sodium-dependent amino acid transporter 0.0182 0.0645 0.1197
Echinococcus granulosus equilibrative nucleoside transporter 0.2526 1 1
Plasmodium falciparum glutathione reductase 0.0049 0.0115 0.1411
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0061 0.0747
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0058 0.0108
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0076 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0035 0.006 0.006
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0058 0.0055
Echinococcus multilocularis neural cadherin 0.0086 0.026 0.026
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0284 0.0284
Echinococcus granulosus pyruvate kinase 0.0224 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2526 1 1
Schistosoma mansoni opsin-like receptor 0.0181 0.0642 0.1191
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Treponema pallidum sodium- and chloride- dependent transporter 0.1073 0.4201 1
Brugia malayi glutathione reductase 0.0049 0.0115 0.0115
Echinococcus granulosus peptide allatostatin:somatostatin 0.0181 0.0642 0.0642
Trypanosoma brucei glucosidase, putative 0.004 0.0077 0.0077
Leishmania major C-8 sterol isomerase-like protein 0.2227 0.8808 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus Peroxidase homolog 0.0265 0.0975 0.0975
Trichomonas vaginalis conserved hypothetical protein 0.0382 0.1442 0.144
Onchocerca volvulus 0.0265 0.0975 0.0975
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.0642 0.1191
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.0645 0.1197
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0002 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0042 0.0078
Loa Loa (eye worm) hypothetical protein 0.0057 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0055
Echinococcus multilocularis neurogenic locus notch protein 0.0086 0.026 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0105 0.0103
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Toxoplasma gondii hypothetical protein 0.0122 0.0404 0.0722
Mycobacterium leprae Probable lipase LipE 0.0035 0.0058 0.0694
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0061 0.0058
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0181 0.0642 0.0642
Loa Loa (eye worm) melatonin receptor type 1A 0.0181 0.0642 0.0642
Brugia malayi hypothetical protein 0.0076 0.0223 0.0223
Onchocerca volvulus 0.0133 0.045 0.045
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0077 0.0077
Entamoeba histolytica hypothetical protein 0.0038 0.0071 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0077 0.0075
Onchocerca volvulus 0.0182 0.0645 0.0645
Schistosoma mansoni hypothetical protein 0.005 0.0119 0.022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0047 0.0105 0.0109
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0131 0.0138
Trypanosoma brucei adenosine transporter 2, putative 0.0439 0.1669 0.1886
Echinococcus multilocularis neurogenic locus notch protein 0.0086 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0182 0.0645 0.0645
Brugia malayi G protein-coupled receptor 0.0181 0.0642 0.0642
Brugia malayi MH2 domain containing protein 0.025 0.0916 0.0916
Leishmania major ATP-dependent phosphofructokinase 0.0219 0.0792 0.089
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0635 0.0635
Trypanosoma brucei protein kinase, putative 0.0053 0.0131 0.0138
Leishmania major nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Echinococcus multilocularis fat cadherin tumor suppressor 0.0086 0.026 0.026
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0023 0.0281
Trypanosoma cruzi pyruvate kinase 2, putative 0.0224 0.0812 0.0912
Onchocerca volvulus 0.0181 0.0642 0.0642
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0046 0.0042
Schistosoma mansoni 6-phosphofructokinase 0.0219 0.0792 0.147
Brugia malayi G protein-coupled receptor F59B2.13 0.0181 0.0642 0.0642
Trypanosoma brucei adenosine transporter 2, putative 0.0439 0.1669 0.1886
Schistosoma mansoni opsin-like receptor 0.0181 0.0642 0.1191
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0061 0.0061
Plasmodium vivax pyruvate kinase 2, putative 0.0115 0.0377 0.4642
Mycobacterium ulcerans beta-lactamase 0.0035 0.0058 0.0694
Loa Loa (eye worm) pyruvate kinase 0.0047 0.0106 0.0106
Loa Loa (eye worm) notch protein 0.0086 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0181 0.0642 0.1191
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0023 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Echinococcus granulosus adenosine kinase 0.1371 0.5391 0.5391
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0169 0.0591 0.0591
Loa Loa (eye worm) blistered cuticle protein 3 0.0265 0.0975 0.0975
Trichomonas vaginalis conserved hypothetical protein 0.0335 0.1255 0.1252
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Brugia malayi hypothetical protein 0.2526 1 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.0591 0.0591
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Echinococcus granulosus neurogenic locus notch protein 0.0086 0.026 0.026
Trypanosoma brucei pyruvate kinase 1, putative 0.0224 0.0812 0.0912
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0156 0.0542 0.0542
Schistosoma mansoni pyruvate kinase 0.0224 0.0812 0.1506
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0224 0.0812 0.0812
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0404 0.0401
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0015 0.0006
Schistosoma mansoni intermediate filament proteins 0.0054 0.0135 0.025
Echinococcus granulosus serotonin receptor 0.0181 0.0642 0.0642
Schistosoma mansoni neuropeptide receptor 0.0181 0.0642 0.1191
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0046 0.0042
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0154 0.0152
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi larval opioid receptor 0.0181 0.0642 0.0642
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.2526 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0181 0.0642 0.0642
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0026 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.025 0.0916 0.0916
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0042 0.0078
Onchocerca volvulus 0.0026 0.0023 0.0023
Leishmania major telomerase reverse transcriptase, putative 0.0087 0.0265 0.0291
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0002 0.0004
Toxoplasma gondii ABC1 family protein 0.0035 0.0058 0.008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0125 0.0125
Plasmodium vivax telomerase reverse transcriptase, putative 0.0087 0.0265 0.3267
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0046 0.0042
Entamoeba histolytica nucleoside transporter, putative 0.0439 0.1669 0.1667
Plasmodium falciparum amino acid transporter, putative 0.0182 0.0645 0.7943
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0023 0.0023
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.0642 0.1191
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0109
Loa Loa (eye worm) pyruvate kinase 0.0224 0.0812 0.0812
Onchocerca volvulus 0.0057 0.0145 0.0145
Brugia malayi ORL1-like opioid receptor 0.0181 0.0642 0.0642
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0115 0.0115
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0047 0.0105 0.0105
Brugia malayi Telomerase reverse transcriptase 0.0232 0.0842 0.0842
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0181 0.0642 0.0642
Toxoplasma gondii hypothetical protein 0.003 0.0037 0.004
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0224 0.0224
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0144 0.0144
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0061 0.0058
Loa Loa (eye worm) phosphofructokinase 0.0219 0.0792 0.0792
Brugia malayi LBP/BPI 0.0057 0.0145 0.0145
Echinococcus granulosus neurogenic locus notch protein 0.0086 0.026 0.026
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0115 0.0119
Trypanosoma brucei pyruvate kinase 1 0.0224 0.0812 0.0912
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0131 0.0138
Loa Loa (eye worm) PDE1B protein 0.0047 0.0105 0.0105
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0058 0.0693
Loa Loa (eye worm) hypothetical protein 0.0053 0.0131 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.009 0.0087
Toxoplasma gondii nucleoside transporter protein 0.0439 0.1669 0.3076
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Onchocerca volvulus 0.0087 0.0264 0.0264
Echinococcus multilocularis pyruvate kinase 0.0224 0.0812 0.0812
Mycobacterium tuberculosis Conserved protein 0.0035 0.0058 0.0693
Onchocerca volvulus 0.0133 0.045 0.045
Trypanosoma brucei adenosine transporter, putative 0.0439 0.1669 0.1886
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0021
Echinococcus granulosus delta-like protein 1 0.0086 0.026 0.026
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0284 0.0284
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.2526 1 1
Loa Loa (eye worm) serotonin transporter b 0.1073 0.4201 0.4201
Loa Loa (eye worm) RecQ helicase 0.0043 0.009 0.009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0416 0.5114
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0002 0.0004
Mycobacterium ulcerans hypothetical protein 0.0035 0.0058 0.0694
Echinococcus granulosus fmrfamide receptor 0.0181 0.0642 0.0642
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0366 0.4497
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.2087 0.8249 0.8249
Echinococcus multilocularis sodium and chloride dependent glycine 0.0182 0.0645 0.0645
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0006 0.0006
Brugia malayi 6-phosphofructokinase 0.0219 0.0792 0.0792
Brugia malayi follicle stimulating hormone receptor 0.0181 0.0642 0.0642
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.0645
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0439 0.1669 0.1886
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0144 0.1749
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0154 0.1745
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0047 0.0105 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0219 0.0792 0.079
Schistosoma mansoni amine GPCR 0.0181 0.0642 0.1191
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0119 0.0119
Trypanosoma brucei C-8 sterol isomerase, putative 0.2227 0.8808 1
Brugia malayi Serotonin receptor 0.0181 0.0642 0.0642
Brugia malayi hypoxia-induced factor 1 0.0313 0.1169 0.1169
Loa Loa (eye worm) hypothetical protein 0.0044 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) Notch2 0.0086 0.026 0.026
Loa Loa (eye worm) pyruvate kinase 0.0224 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0002 0.0002
Toxoplasma gondii nucleoside transporter protein 0.0439 0.1669 0.3076
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0182 0.0645 0.0645
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0468 0.0521
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Echinococcus multilocularis neuropeptide s receptor 0.0181 0.0642 0.0642
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0439 0.1669 0.1886
Brugia malayi hypothetical protein 0.0439 0.1669 0.1669
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0061 0.0058
Schistosoma mansoni notch 0.0086 0.026 0.0481
Trypanosoma brucei adenosine transporter 2, putative 0.0439 0.1669 0.1886
Entamoeba histolytica phosphofructokinase, putative 0.0219 0.0792 0.079
Echinococcus multilocularis serotonin transporter 0.1073 0.4201 0.4201
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.001
Leishmania major nucleobase transporter 0.0439 0.1669 0.1886
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0002 0.0002
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni hypothetical protein 0.0181 0.0642 0.1191
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Toxoplasma gondii pyruvate kinase PyKII 0.0115 0.0377 0.0673
Loa Loa (eye worm) hypothetical protein 0.0102 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0335 0.1255 0.1252
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0058 0.0058
Plasmodium falciparum GAF domain-related protein, putative 0.0122 0.0404 0.4969
Mycobacterium ulcerans endonuclease IV 0.008 0.0237 0.2897
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0047 0.0105 0.0109
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0002 0.0002
Entamoeba histolytica fructokinase, putative 0.0156 0.0542 0.0539
Entamoeba histolytica hypothetical protein 0.0038 0.0071 0.0068
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0499 0.0499
Trypanosoma cruzi adenosine kinase, putative 0.0156 0.0542 0.0605
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0181 0.0642 0.0642
Echinococcus multilocularis protein patched 0.0044 0.0094 0.0094
Onchocerca volvulus 0.0086 0.026 0.026
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0382 0.1442 0.1628
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Trypanosoma brucei purine nucleoside transporter 0.0439 0.1669 0.1886
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.0642 0.0642
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0037 0.0451
Loa Loa (eye worm) hypothetical protein 0.1073 0.4201 0.4201
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Brugia malayi STAT protein, DNA binding domain containing protein 0.0139 0.0471 0.0471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.0642 0.0642
Brugia malayi bHLH-PAS transcription factor 0.0075 0.0217 0.0217
Brugia malayi PXA domain containing protein 0.0021 0.0002 0.0002
Brugia malayi sulfakinin receptor protein 0.0181 0.0642 0.0642
Leishmania major pyruvate kinase 0.0224 0.0812 0.0912
Loa Loa (eye worm) hypothetical protein 0.0122 0.0404 0.0404
Loa Loa (eye worm) pyruvate kinase-PB 0.0156 0.0542 0.0542
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0023 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0077 0.0075
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0182 0.0645 0.0645
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0047 0.0105 0.0105
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0635 0.0635
Brugia malayi notch-like transmembrane receptor 0.0086 0.026 0.026
Brugia malayi Calcium binding EGF domain containing protein 0.0086 0.026 0.026
Trypanosoma cruzi nucleobase transporter, putative 0.0439 0.1669 0.1886
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0645 0.1197
Brugia malayi Pyruvate kinase, muscle isozyme 0.0224 0.0812 0.0812
Echinococcus multilocularis fmrfamide receptor 0.0181 0.0642 0.0642
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0047 0.0105 0.0105
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0439 0.1669 0.1886
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0002 0.0002
Schistosoma mansoni notch 0.0086 0.026 0.0481
Entamoeba histolytica phosphofructokinase, putative 0.0219 0.0792 0.079
Trypanosoma brucei unspecified product 0.0439 0.1669 0.1886
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Onchocerca volvulus Putative cubilin 0.0086 0.026 0.026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0416 0.5114
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.3098
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Trypanosoma brucei nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Mycobacterium ulcerans putative regulatory protein 0.0075 0.0217 0.2659
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.0642 0.0642
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0034 0.042
Onchocerca volvulus Peroxidasin homolog 0.0265 0.0975 0.0975
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0058 0.0056
Brugia malayi Pre-SET motif family protein 0.0217 0.0783 0.0783
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0156 0.0542 0.6663
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Loa Loa (eye worm) MH2 domain-containing protein 0.025 0.0916 0.0916
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0047 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0058 0.0694
Trichomonas vaginalis ribokinase, putative 0.0156 0.0542 0.0539
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0182 0.0645 0.0645
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0042 0.0042
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0077 0.0075
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Echinococcus granulosus Niemann Pick C1 protein 0.0146 0.0503 0.0503
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0058 0.0056
Schistosoma mansoni slit 0.0086 0.026 0.0481
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0023 0.0281
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0182 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.01 0.0098
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0094 0.0094
Echinococcus granulosus sodium and chloride dependent glycine 0.0182 0.0645 0.0645
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0047 0.0105 0.0105
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0023 0.0015
Mycobacterium ulcerans putative regulatory protein 0.0122 0.0404 0.4957
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0133 0.045 0.045
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0103
Brugia malayi hypothetical protein 0.0156 0.0542 0.0542
Echinococcus granulosus notch 0.0086 0.026 0.026
Mycobacterium leprae conserved hypothetical protein 0.0122 0.0404 0.4957
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0115 0.1411
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0077 0.0075
Onchocerca volvulus 0.0086 0.026 0.026
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Echinococcus multilocularis 6 phosphofructokinase 0.0219 0.0792 0.0792
Brugia malayi Adenosine kinase-like 0.1371 0.5391 0.5391
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.2526 1 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0015 0.0165
Brugia malayi Augmenter of liver regeneration 0.0036 0.0061 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0181 0.0642 0.0642
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0023 0.0021
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0262 0.3213
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Leishmania major adenosine kinase-like protein 0.0156 0.0542 0.0605
Brugia malayi hypothetical protein 0.0127 0.0424 0.0424
Onchocerca volvulus 0.0265 0.0975 0.0975
Schistosoma mansoni amine GPCR 0.0181 0.0642 0.1191
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Schistosoma mansoni biogenic amine receptor 0.0181 0.0642 0.1191
Mycobacterium tuberculosis Conserved protein 0.0035 0.0058 0.0693
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0015 0.0006
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0086 0.026 0.026
Schistosoma mansoni notch 0.0086 0.026 0.0481
Brugia malayi Muscle positioning protein 4 0.0086 0.026 0.026
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0182 0.0645 0.7904
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0154 0.0332
Echinococcus multilocularis fibropellin Ia 0.0086 0.026 0.026
Echinococcus granulosus neuropeptide FF receptor 2 0.0181 0.0642 0.0642
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0131 0.0243
Echinococcus granulosus G protein coupled receptor 139 0.0181 0.0642 0.0642
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0181 0.0642 0.1191
Toxoplasma gondii hypothetical protein 0.0335 0.1255 0.2305
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0154 0.19
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0094 0.0091
Leishmania major tagatose-6-phosphate kinase-like protein 0.0156 0.0542 0.0605
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Schistosoma mansoni hypothetical protein 0.052 0.1993 0.3697
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0077 0.0115
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Onchocerca volvulus 0.0181 0.0642 0.0642
Echinococcus multilocularis Niemann Pick C1 protein 0.0146 0.0503 0.0503
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0181 0.0642 0.0642
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0023 0.0099
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0023 0.0015
Toxoplasma gondii nucleoside transporter protein 0.0439 0.1669 0.3076
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0224 0.0224
Trichomonas vaginalis phosphofructokinase, putative 0.0219 0.0792 0.079
Loa Loa (eye worm) animal heme peroxidase 0.0265 0.0975 0.0975
Loa Loa (eye worm) hypothetical protein 0.2526 1 1
Plasmodium vivax phosphodiesterase gamma, putative 0.0047 0.0105 0.1298
Brugia malayi Dopamine receptor 0.0181 0.0642 0.0642
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0058 0.0715
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.0901 0.0901
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0125 0.0125
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0181 0.0642 0.0642
Schistosoma mansoni peroxidasin 0.0265 0.0975 0.1808
Trypanosoma brucei Emopamil binding protein, putative 0.0138 0.0468 0.0521
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0366 0.4497
Schistosoma mansoni equilibrative nucleoside transporter 0.0439 0.1669 0.3095
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0061 0.0084
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0131 0.0131
Mycobacterium tuberculosis Adenosine kinase 0.0156 0.0542 0.6661
Loa Loa (eye worm) hypothetical protein 0.0076 0.0223 0.0223
Echinococcus granulosus protein jagged 2 0.0086 0.026 0.026
Toxoplasma gondii hypothetical protein 0.0182 0.0645 0.1172
Onchocerca volvulus 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0138 0.0468 0.0468
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0023 0.0021
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0169 0.0591 0.0589
Echinococcus granulosus tumor protein p63 0.0681 0.2636 0.2636
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0047 0.0105 0.0105
Onchocerca volvulus 0.0133 0.045 0.045
Entamoeba histolytica kinase, PfkB family 0.0156 0.0542 0.0539
Onchocerca volvulus 0.0182 0.0645 0.0645
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0182 0.0645 0.0645
Echinococcus multilocularis pyruvate kinase 0.0224 0.0812 0.0812
Leishmania major ribokinase, putative 0.0156 0.0542 0.0605
Onchocerca volvulus 0.0133 0.045 0.045
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0058 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.1298
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0037 0.0451
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.0327 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Toxoplasma gondii hypothetical protein 0.0182 0.0645 0.1172
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.0642 0.1191
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0131 0.0026
Giardia lamblia Pyruvate kinase 0.0115 0.0377 0.0274
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0219 0.0792 0.089
Schistosoma mansoni neuropeptide receptor 0.0181 0.0642 0.1191
Schistosoma mansoni biogenic amine (5HT) receptor 0.0181 0.0642 0.1191
Onchocerca volvulus 0.0035 0.0058 0.0058
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0047 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.0645
Brugia malayi hypothetical protein 0.0182 0.0645 0.0645
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0284 0.0527
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0019
Brugia malayi hypothetical protein 0.0246 0.0901 0.0901
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0006 0.0006
Brugia malayi Serotonin receptor 0.0181 0.0642 0.0642
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2526 1 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0642 0.0642
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.1298
Echinococcus granulosus tachykinin peptides receptor 99D 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Trypanosoma brucei adenosine transporter 2, putative 0.0439 0.1669 0.1886
Onchocerca volvulus 0.0035 0.0058 0.0058
Loa Loa (eye worm) norepinephrine transporter 0.1073 0.4201 0.4201
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0061 0.0061
Echinococcus granulosus single minded 2 0.0075 0.0217 0.0217
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0058 0.0058
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0122 0.0404 0.4956
Echinococcus multilocularis expressed conserved protein 0.0096 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Schistosoma mansoni opsin-like receptor 0.0181 0.0642 0.1191
Brugia malayi hypothetical protein 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Echinococcus multilocularis serotonin receptor 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0105 0.0103
Onchocerca volvulus Peroxidasin homolog 0.0265 0.0975 0.0975
Brugia malayi 6-phosphofructokinase 0.0219 0.0792 0.0792
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0076 0.0223 0.0223
Onchocerca volvulus 0.0133 0.045 0.045
Onchocerca volvulus 0.0181 0.0642 0.0642
Trypanosoma brucei ribokinase, putative 0.0156 0.0542 0.0605
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Brugia malayi Peroxidasin 0.0265 0.0975 0.0975
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Loa Loa (eye worm) hypothetical protein 0.2227 0.8808 0.8808
Echinococcus granulosus expressed protein 0.0411 0.156 0.156
Loa Loa (eye worm) hypothetical protein 0.0246 0.0901 0.0901
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Schistosoma mansoni histamine h1 receptor 0.0181 0.0642 0.1191
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0169 0.0591 0.0589
Onchocerca volvulus 0.0075 0.0217 0.0217
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0002 0.0002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Onchocerca volvulus Pyruvate kinase homolog 0.0224 0.0812 0.0812
Echinococcus multilocularis serotonin receptor 0.0181 0.0642 0.0642
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0061 0.0061
Brugia malayi Calcium binding EGF domain containing protein 0.0086 0.026 0.026
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0262 0.3213
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0366 0.4498
Plasmodium vivax pyruvate kinase, putative 0.0224 0.0812 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.0642 0.0642
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0034 0.0034
Giardia lamblia High cysteine protein 0.0086 0.026 0.0156
Entamoeba histolytica hypothetical protein 0.0038 0.0071 0.0068
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0219 0.0792 0.089
Echinococcus multilocularis pyruvate kinase 0.0115 0.0377 0.0377
Trypanosoma cruzi nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0131 0.0131
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0061 0.0084
Schistosoma mansoni neuropeptide receptor 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0057 0.0145 0.0145
Brugia malayi RE15519p 0.0181 0.0642 0.0642
Schistosoma mansoni amine GPCR 0.0181 0.0642 0.1191
Onchocerca volvulus Pyruvate kinase homolog 0.0224 0.0812 0.0812
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0103
Echinococcus granulosus 6 phosphofructokinase 0.0219 0.0792 0.0792
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0077 0.0075
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0047 0.0105 0.0105
Leishmania major nucleobase transporter 0.0439 0.1669 0.1886
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0154 0.0049
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0382 0.1442 0.1628
Loa Loa (eye worm) hypothetical protein 0.0439 0.1669 0.1669
Leishmania major hypothetical protein, conserved 0.0047 0.0105 0.0109
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0169 0.0591 0.0589
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0077 0.0075
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0002 0.0004
Schistosoma mansoni alpha glucosidase 0.004 0.0077 0.0143
Giardia lamblia Hypothetical protein 0.2526 1 1
Leishmania major tagatose-6-phosphate kinase-like protein 0.0156 0.0542 0.0605
Schistosoma mansoni hypothetical protein 0.0042 0.0087 0.0162
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0023 0.0023
Onchocerca volvulus 0.0086 0.026 0.026
Mycobacterium ulcerans lipase LipD 0.0035 0.0058 0.0694
Brugia malayi Muscleblind-like protein 0.0145 0.0499 0.0499
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0468 0.0521
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0131 0.0129
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus multilocularis neurogenic locus notch protein 4 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0133 0.045 0.045
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.0642 0.0642
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0382 0.1442 0.1628
Onchocerca volvulus 0.0181 0.0642 0.0642
Plasmodium vivax hypothetical protein, conserved 0.0122 0.0404 0.4969
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.0642 0.0642
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.0645
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0131 0.0129
Trypanosoma brucei telomerase reverse transcriptase 0.0087 0.0265 0.0291
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0046 0.055
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0156 0.0542 0.0539
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0068 0.0189 0.0189
Loa Loa (eye worm) pyruvate kinase 0.0224 0.0812 0.0812
Echinococcus granulosus protein jagged 1 0.0086 0.026 0.026
Leishmania major adenosine kinase-like protein 0.0156 0.0542 0.0605
Chlamydia trachomatis pyruvate kinase 0.0224 0.0812 1
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0284 0.0282
Echinococcus multilocularis musashi 0.0054 0.0135 0.0135
Brugia malayi Cadherin domain containing protein 0.0086 0.026 0.026
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0131 0.0131
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0284 0.0312
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Plasmodium vivax amine transporter, putative 0.0182 0.0645 0.7943
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0284 0.0282
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0047 0.0105 0.0109
Schistosoma mansoni sodium/chloride dependent transporter 0.1073 0.4201 0.7792
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Echinococcus granulosus 7TM GPCR rhodopsin 0.0181 0.0642 0.0642
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0047 0.0105 0.0195
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0002 0.0002
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0154 0.0259
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0219 0.0792 0.9756
Onchocerca volvulus 0.0182 0.0645 0.0645
Schistosoma mansoni peroxidasin 0.0265 0.0975 0.1808
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Schistosoma mansoni aryl hydrocarbon receptor 0.0101 0.0322 0.0598
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0133 0.045 0.045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Echinococcus granulosus fibropellin Ia 0.0086 0.026 0.026
Onchocerca volvulus Neuropeptide F receptor homolog 0.0181 0.0642 0.0642
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.018 0.0635 0.0635
Trichomonas vaginalis conserved hypothetical protein 0.0335 0.1255 0.1252
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.001 0.0007
Echinococcus granulosus neural cadherin 0.0086 0.026 0.026
Schistosoma mansoni septate junction protein 0.0086 0.026 0.0481
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0077 0.0077
Onchocerca volvulus 0.0076 0.0223 0.0223
Leishmania major hypothetical protein, conserved 0.0138 0.0468 0.0521
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0181 0.0642 0.0642
Trypanosoma brucei adenosine kinase, putative 0.1371 0.5391 0.6117
Loa Loa (eye worm) STAT protein 0.0139 0.0471 0.0471
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0416 0.5116
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi Melatonin receptor type 1A 0.0181 0.0642 0.0642
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Brugia malayi hypothetical protein 0.034 0.1275 0.1275
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.2526 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0145 0.0145
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0115 0.1391
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.001
Echinococcus granulosus muscleblind protein 0.0145 0.0499 0.0499
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0046 0.0046
Giardia lamblia Ribokinase 0.0156 0.0542 0.0441
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0002 0.0002
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0284 0.0312
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0058 0.0693
Schistosoma mansoni biogenic amine receptor 0.0181 0.0642 0.1191
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.1172
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0237 0.2913
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0237 0.2913
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0058 0.0056
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0262 0.0262
Toxoplasma gondii thioredoxin reductase 0.0049 0.0115 0.0185
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0133 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0086 0.0262 0.0262
Brugia malayi Calcium binding EGF domain containing protein 0.0086 0.026 0.026
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0058 0.0056
Echinococcus granulosus ribokinase 0.0156 0.0542 0.0542
Plasmodium falciparum telomerase reverse transcriptase 0.0087 0.0265 0.3267
Brugia malayi phosphofructokinase 0.0219 0.0792 0.0792
Giardia lamblia Telomerase catalytic subunit 0.0087 0.0265 0.0162
Echinococcus multilocularis neuropeptide receptor 0.0181 0.0642 0.0642
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0026 0.0019
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0094 0.0094
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0015 0.0188
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0468 0.0521
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0105 0.0103
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0169 0.0591 0.1096
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Entamoeba histolytica hypothetical protein 0.0024 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0105
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0047 0.0105 0.0195
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0181 0.0642 0.0642
Schistosoma mansoni notch 0.0086 0.026 0.0481
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0071 0.0131
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0077 0.0075
Echinococcus multilocularis G protein coupled receptor 139 0.0181 0.0642 0.0642
Schistosoma mansoni alpha-1 adrenergic receptor 0.0181 0.0642 0.1191
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0181 0.0642 0.1191
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0131 0.0138
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0058 0.0693
Onchocerca volvulus Pyruvate kinase homolog 0.0224 0.0812 0.0812
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Brugia malayi Pyruvate kinase, M2 isozyme 0.0224 0.0812 0.0812
Entamoeba histolytica pyruvate kinase, putative 0.0156 0.0542 0.0539
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0147 0.0147
Echinococcus granulosus serotonin transporter 0.1073 0.4201 0.4201
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0046 0.0046
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0219 0.0792 0.9754
Plasmodium vivax hypothetical protein, conserved 0.0182 0.0645 0.7943
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0316 0.0586
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0154 0.19
Plasmodium falciparum transporter, putative 0.0182 0.0645 0.7943
Schistosoma mansoni hypothetical protein 0.0086 0.026 0.0481
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0023 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0182 0.0645 0.0645
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0047 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0181 0.0642 0.1191
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.0642 0.0642
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0382 0.1442 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0131 0.0129
Schistosoma mansoni lamin 0.0054 0.0135 0.025
Schistosoma mansoni cell polarity protein 0.0086 0.026 0.0481
Loa Loa (eye worm) hypothetical protein 0.0087 0.0264 0.0264
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0042 0.0042
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0047 0.0105 0.0105
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0319 0.119 0.119
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0284 0.0312
Onchocerca volvulus 0.0035 0.0058 0.0058
Echinococcus granulosus 7tm_1 domain containing protein 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0131 0.0138
Echinococcus granulosus slit 2 protein 0.0086 0.026 0.026
Echinococcus multilocularis expressed protein 0.0411 0.156 0.156
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0115 0.0115
Onchocerca volvulus 0.0076 0.0223 0.0223
Brugia malayi Animal haem peroxidase family protein 0.0265 0.0975 0.0975
Loa Loa (eye worm) animal heme peroxidase 0.0265 0.0975 0.0975
Echinococcus multilocularis allatostatin A receptor 0.0181 0.0642 0.0642
Echinococcus granulosus geminin 0.052 0.1993 0.1993
Onchocerca volvulus 0.0086 0.026 0.026
Onchocerca volvulus 0.0181 0.0642 0.0642
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0181 0.0642 0.0642
Toxoplasma gondii kinase, pfkB family protein 0.0156 0.0542 0.0979
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0237 0.0237
Echinococcus granulosus alpha 1A adrenergic receptor 0.0181 0.0642 0.0642
Echinococcus granulosus expressed conserved protein 0.0096 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0133 0.045 0.045
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0224 0.0812 0.9997
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.0642 0.0642
Echinococcus multilocularis somatostatin receptor 0.0181 0.0642 0.0642
Schistosoma mansoni growth hormone secretagogue receptor 0.0181 0.0642 0.1191
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Echinococcus multilocularis orexin receptor type 2 0.0181 0.0642 0.0642
Trypanosoma brucei purine nucleoside transporter 0.0439 0.1669 0.1886
Toxoplasma gondii EGF family domain-containing protein 0.0086 0.026 0.0454
Schistosoma mansoni survival motor neuron protein 0.005 0.0119 0.022
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0169 0.0591 0.0591
Giardia lamblia Pyruvate kinase 0.0224 0.0812 0.0714
Echinococcus granulosus hypothetical protein 0.0181 0.0642 0.0642
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0181 0.0642 0.0642
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0154 0.1745
Echinococcus granulosus pyruvate kinase 0.0224 0.0812 0.0812
Schistosoma mansoni hypothetical protein 0.0035 0.006 0.0111
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0382 0.1442 0.144
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0052 0.0125 0.0125
Schistosoma mansoni adenosine kinase 0.1371 0.5391 1
Loa Loa (eye worm) hypothetical protein 0.1371 0.5391 0.5391
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0047 0.0105 0.0105
Trypanosoma cruzi ribokinase, putative 0.0156 0.0542 0.0605
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0077 0.0077
Entamoeba histolytica phosphofructokinase, putative 0.0219 0.0792 0.079
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0105 0.0109
Schistosoma mansoni hypothetical protein 0.052 0.1993 0.3697
Onchocerca volvulus 0.0247 0.0903 0.0903
Echinococcus granulosus peroxidasin 0.0265 0.0975 0.0975
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0642 0.0642
Trichomonas vaginalis phosphofructokinase, putative 0.0219 0.0792 0.079
Leishmania major adenosine kinase, putative 0.1371 0.5391 0.6117
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0105 0.0109
Echinococcus granulosus sodium and chloride dependent glycine 0.0182 0.0645 0.0645
Brugia malayi Animal haem peroxidase family protein 0.0265 0.0975 0.0975
Echinococcus granulosus pyruvate kinase 0.0115 0.0377 0.0377
Trichomonas vaginalis set domain proteins, putative 0.0247 0.0902 0.09
Echinococcus multilocularis sex peptide receptor 0.0181 0.0642 0.0642
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0416 0.5114
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Echinococcus granulosus lamin dm0 0.0054 0.0135 0.0135
Schistosoma mansoni hypothetical protein 0.0181 0.0642 0.1191
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0156 0.0542 0.6661
Schistosoma mansoni biogenic amine (5HT) receptor 0.0181 0.0642 0.1191
Onchocerca volvulus 0.1073 0.4201 0.4201
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Trypanosoma cruzi adenosine kinase, putative 0.0156 0.0542 0.0605
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0087 0.0265 0.0291
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0002 0.0002
Echinococcus multilocularis slit 2 protein 0.0086 0.026 0.026
Echinococcus granulosus g protein coupled receptor 0.0181 0.0642 0.0642
Leishmania major cytochrome p450-like protein 0.0032 0.0046 0.0042
Loa Loa (eye worm) hypothetical protein 0.0156 0.0542 0.0542
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0154 0.19
Echinococcus multilocularis neurogenic locus protein delta 0.0086 0.026 0.026
Schistosoma mansoni adenosine kinase 0.1371 0.5391 1
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0076 0.0223 0.0223
Schistosoma mansoni alpha-glucosidase 0.0155 0.0535 0.0992
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0131 0.0131
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.0642 0.0642
Trypanosoma cruzi nucleoside transporter-like, putative 0.0439 0.1669 0.1886
Trypanosoma cruzi nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0382 0.1442 0.1442
Mycobacterium ulcerans fructokinase, PfkB 0.0156 0.0542 0.6663
Echinococcus multilocularis neuropeptide FF receptor 2 0.0181 0.0642 0.0642
Echinococcus granulosus lamin 0.0054 0.0135 0.0135
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0284 0.0284
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0002 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0125 0.0125
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0105 0.0168
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2227 0.8808 1
Schistosoma mansoni hypothetical protein 0.0042 0.0087 0.0162
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.0327 0.0327
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.0645
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0642 0.0642
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0131 0.0138
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0181 0.0642 0.0642
Trypanosoma cruzi nucleobase transporter, putative 0.0439 0.1669 0.1886
Brugia malayi hypothetical protein 0.0181 0.0642 0.0642
Brugia malayi PXA domain containing protein 0.0021 0.0002 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.0642 0.0642
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0366 0.4497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Brugia malayi Pre-SET motif family protein 0.0031 0.0042 0.0042
Echinococcus granulosus g-protein coupled receptor 0.0181 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0076 0.0223 0.0223
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.009 0.0087
Loa Loa (eye worm) hypothetical protein 0.0265 0.0975 0.0975
Trypanosoma cruzi nucleobase transporter, putative 0.0439 0.1669 0.1886
Leishmania major trypanothione reductase 0.0049 0.0115 0.0119
Onchocerca volvulus 0.0054 0.0135 0.0135
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0366 0.4497
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0002
Plasmodium falciparum phosphodiesterase delta, putative 0.0047 0.0105 0.1298
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0219 0.0792 0.1857
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.1172
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Loa Loa (eye worm) beta-lactamase 0.0035 0.0058 0.0058
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0181 0.0642 0.1191
Onchocerca volvulus 0.0031 0.0042 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0642 0.1191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.0058
Brugia malayi beta-lactamase 0.0035 0.0058 0.0058
Trypanosoma cruzi adenosine kinase, putative 0.1371 0.5391 0.6117
Plasmodium falciparum pyruvate kinase 2 0.0115 0.0377 0.4642
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0156 0.0542 0.0542
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0439 0.1669 0.1667
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0182 0.0645 0.1197
Trypanosoma cruzi pyruvate kinase 2, putative 0.0224 0.0812 0.0912
Brugia malayi Tachykinin-like peptides receptor 99D 0.0181 0.0642 0.0642
Echinococcus multilocularis tumor protein p63 0.0681 0.2636 0.2636
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0439 0.1669 0.1667
Brugia malayi Animal haem peroxidase family protein 0.0265 0.0975 0.0975
Loa Loa (eye worm) hypothetical protein 0.0086 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0042 0.0087 0.0162
Onchocerca volvulus 0.0181 0.0642 0.0642
Onchocerca volvulus 0.0265 0.0975 0.0975
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0058 0.0693
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0047 0.0105 0.1298
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0023
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0182 0.0645 0.1172
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0133 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0182 0.0645 0.0645
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0181 0.0642 0.0642
Schistosoma mansoni amine GPCR 0.0181 0.0642 0.1191
Echinococcus multilocularis protein jagged 1 0.0086 0.026 0.026
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0077 0.0075
Trypanosoma cruzi nucleoside transporter 1, putative 0.0439 0.1669 0.1886
Brugia malayi neuropeptide F receptor 0.0181 0.0642 0.0642
Brugia malayi EGF-like domain containing protein 0.0086 0.026 0.026
Loa Loa (eye worm) TYRA-2 protein 0.0181 0.0642 0.0642
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0058 0.0058
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.0642 0.0642
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0002 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0642 0.1191
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0154 0.0152
Echinococcus multilocularis pyruvate kinase 0.0115 0.0377 0.0377
Leishmania major protein kinase, putative 0.0027 0.0026 0.0019
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0002 0.0002
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0015 0.0165
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0812 1
Brugia malayi Ribokinase 0.0156 0.0542 0.0542
Echinococcus granulosus somatostatin receptor 0.0181 0.0642 0.0642
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0382 0.1442 0.1628
Echinococcus multilocularis sodium and chloride dependent glycine 0.0182 0.0645 0.0645
Echinococcus multilocularis geminin 0.052 0.1993 0.1993

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 500 nM TNF-alpha release is determined to know human (JN.24 cloned)Vgamma2Vdelta2 T cell stimulation ChEMBL. 15357974
EC50 (functional) = 1200 nM Proliferation of human (JN.24 cloned)Vgamma2Vdelta2 T cell ChEMBL. 15357974

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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