Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0081 | 0.0074 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0081 | 0.0081 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.003 | 0.0081 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0006 | 0.0006 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0338 | 0.1715 | 0.1705 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1715 | 0.1715 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0338 | 0.1715 | 0.1705 |
Plasmodium vivax | DNA mismatch repair protein MLH, putative | 0.0033 | 0.0099 | 0.0083 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0338 | 0.1715 | 0.1715 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0054 | 0.021 | 0.021 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0338 | 0.1715 | 0.1705 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0241 | 0.0229 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.0229 | 0.0222 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Echinococcus multilocularis | endoplasmin | 0.1596 | 0.8384 | 0.8384 |
Onchocerca volvulus | 0.0063 | 0.0256 | 0.0321 | |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0008 | 0.0002 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.005 | 0.0189 | 0.0177 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0081 | 0.0081 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0338 | 0.1715 | 0.1701 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.0338 | 0.1715 | 0.1705 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Schistosoma mansoni | Microrchidia 2a | 0.0033 | 0.0099 | 0.0093 |
Schistosoma mansoni | lamin | 0.003 | 0.0082 | 0.0076 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0167 | 0.081 | 0.081 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0081 | 0.0074 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0071 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0687 | 0.3564 | 0.356 |
Schistosoma mansoni | microrchidia 2a | 0.0033 | 0.0099 | 0.0093 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0216 | 0.021 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0081 | 0.0081 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4773 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0338 | 0.1715 | 0.1715 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0548 | 0.0548 |
Leishmania major | DNA topoisomerase ii | 0.0338 | 0.1715 | 0.1705 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Treponema pallidum | chemotaxis histidine kinase (cheA) | 0.0338 | 0.1715 | 0.195 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0016 | 0.0004 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0082 | 0.0076 |
Mycobacterium tuberculosis | Conserved protein | 0.0338 | 0.1715 | 0.203 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0115 | 0.0532 | 0.0526 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | heat shock protein 90 | 0.1563 | 0.8208 | 0.8208 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0338 | 0.1715 | 0.203 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0376 | 0.1919 | 0.1913 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0167 | 0.081 | 0.081 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0338 | 0.1715 | 0.1701 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0082 | 0.0082 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.1596 | 0.8384 | 0.8382 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Onchocerca volvulus | 0.0054 | 0.0208 | 0.0233 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0071 | 0.0059 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0016 | 0.0016 |
Brugia malayi | hypothetical protein | 0.0263 | 0.132 | 0.1314 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0021 | 0.0036 | 0.003 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0919 | 0.4792 | 0.5664 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0449 | 0.2301 | 0.2731 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.008 | 0.0068 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0338 | 0.1715 | 0.1701 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0021 | 0.0036 | 0.0036 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0016 | 0.0004 |
Onchocerca volvulus | 0.003 | 0.0081 | 0.0002 | |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0338 | 0.1715 | 0.181 |
Mycobacterium leprae | Probable two component sensor kinase MprB | 0.0338 | 0.1715 | 0.1967 |
Trichomonas vaginalis | heat shock protein, putative | 0.0816 | 0.4248 | 0.4241 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0338 | 0.1715 | 0.1705 |
Schistosoma mansoni | regulator of G protein signaling | 0.0021 | 0.0036 | 0.003 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0338 | 0.1715 | 0.1715 |
Trichomonas vaginalis | heat shock protein, putative | 0.1901 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0081 | 0.0074 |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0338 | 0.1715 | 0.203 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0338 | 0.1715 | 0.1705 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | endoplasmin, putative | 0.1154 | 0.604 | 0.6035 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0338 | 0.1715 | 0.203 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0082 | 0.0082 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0016 | 0.0004 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0036 | 0.003 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.1563 | 0.8208 | 0.8206 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0081 | 0.0074 |
Echinococcus granulosus | endoplasmin | 0.1596 | 0.8384 | 0.8384 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.005 | 0.0189 | 0.0177 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0021 | 0.0036 | 0.0036 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0449 | 0.2301 | 0.253 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.1901 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0081 | 0.0074 |
Leishmania major | mismatch repair protein, putative | 0.0033 | 0.0099 | 0.0087 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0338 | 0.1715 | 0.1705 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0438 | 0.2242 | 0.2242 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0338 | 0.1715 | 0.1705 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.0338 | 0.1715 | 0.1705 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0017 | 0.0012 | 0.0012 |
Brugia malayi | heat shock protein 90 | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0189 | 0.0177 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0338 | 0.1715 | 0.1701 |
Brugia malayi | DNA mismatch repair protein MutL containing protein | 0.0033 | 0.0099 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.132 | 0.132 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0006 | 0.0006 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0338 | 0.1715 | 0.1701 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0036 | 0.003 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0167 | 0.081 | 0.0804 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0082 | 0.0076 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1705 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0919 | 0.4792 | 0.474 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0338 | 0.1715 | 0.195 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0338 | 0.1715 | 0.1705 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0081 | 0.0074 |
Echinococcus multilocularis | 0.0051 | 0.0196 | 0.0196 | |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0338 | 0.1715 | 0.195 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1705 |
Toxoplasma gondii | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0338 | 0.1715 | 0.1715 |
Brugia malayi | PAS domain containing protein | 0.0115 | 0.0532 | 0.0526 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0021 | 0.0036 | 0.003 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.1596 | 0.8384 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0189 | 0.0177 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0263 | 0.132 | 0.132 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.1596 | 0.8384 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0079 | 0.0079 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0338 | 0.1715 | 0.181 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0071 | 0.0065 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0338 | 0.1715 | 0.1705 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0071 | 0.0055 |
Giardia lamblia | Pms1-like protein | 0.0338 | 0.1715 | 0.1632 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.0256 | 0.024 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.1061 | 0.5548 | 0.5548 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0081 | 0.0074 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0081 | 0.0074 |
Echinococcus granulosus | axis inhibition protein axin | 0.0021 | 0.0036 | 0.0036 |
Toxoplasma gondii | heat shock protein HSP90 | 0.1901 | 1 | 1 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0021 | 0.0033 | 0.0021 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0008 | 0.0008 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0021 | 0.0036 | 0.0036 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0101 | 0.0089 |
Trypanosoma cruzi | mismatch repair protein MLH1, putative | 0.0033 | 0.0099 | 0.0087 |
Schistosoma mansoni | heat shock protein | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0216 | 0.0216 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0063 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0081 | 0.0081 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0189 | 0.0177 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1684 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0338 | 0.1715 | 0.203 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0081 | 0.0074 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0021 | 0.0036 | 0.0036 |
Trypanosoma cruzi | heat shock protein, putative | 0.1061 | 0.5548 | 0.5542 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0081 | 0.0074 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0849 | 0.4424 | 0.4404 |
Plasmodium vivax | heat shock protein 90, putative | 0.1061 | 0.5548 | 0.5541 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0017 | 0.0012 | 0.0006 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.003 | 0.0081 | 0.0069 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0338 | 0.1715 | 0.1705 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0099 | 0.0093 |
Brugia malayi | Probable DNA topoisomerase II | 0.0338 | 0.1715 | 0.1709 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0256 | 0.025 |
Loa Loa (eye worm) | heat shock protein 90 | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | RGS-3 protein | 0.0021 | 0.0036 | 0.0036 |
Brugia malayi | DNA mismatch repair protein MutL containing protein | 0.0033 | 0.0099 | 0.0093 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0338 | 0.1715 | 0.203 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0402 | 0.0396 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0016 | 0.0016 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0017 | 0.0012 | 0.0006 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0189 | 0.0177 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0123 | 0.0117 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0338 | 0.1715 | 0.181 |
Schistosoma mansoni | axis inhibition protein axin | 0.0021 | 0.0036 | 0.003 |
Trypanosoma brucei | mismatch repair protein PMS1, putative | 0.0033 | 0.0099 | 0.0087 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0082 | 0.007 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1705 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0338 | 0.1715 | 0.1705 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Plasmodium vivax | DNA mismatch repair protein PMS1, putative | 0.0033 | 0.0099 | 0.0083 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0021 | 0.0036 | 0.0036 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.015 | 0.0138 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.005 | 0.0189 | 0.0153 |
Mycobacterium ulcerans | heat shock protein 90 | 0.1596 | 0.8384 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Brugia malayi | Pre-SET motif family protein | 0.0438 | 0.2242 | 0.2237 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0021 | 0.0036 | 0.003 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.1061 | 0.5548 | 0.5548 |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0391 | 0.0385 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | heat shock protein 90 | 0.1901 | 1 | 1 |
Trypanosoma brucei | heat shock protein 84, putative | 0.1061 | 0.5548 | 0.5542 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0021 | 0.0036 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0021 | 0.0036 | 0.0036 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0054 | 0.021 | 0.0204 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0167 | 0.081 | 0.081 |
Trichomonas vaginalis | mismatch repair protein Pms1 (mutL homolog) | 0.0033 | 0.0099 | 0.0087 |
Echinococcus granulosus | lamin | 0.003 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0006 | 0.0006 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0095 | 0.0083 |
Echinococcus multilocularis | MORC family CW type zinc finger protein 2B | 0.0033 | 0.0099 | 0.0099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0054 | 0.021 | 0.021 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.005 | 0.0189 | 0.0177 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0081 | 0.0074 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0021 | 0.0036 | 0.003 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0021 | 0.0036 | 0.003 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0241 | 0.0241 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0099 | 0.0093 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.1061 | 0.5548 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0241 | 0.0269 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.003 | 0.0081 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0081 | 0.0074 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0256 | 0.0256 |
Mycobacterium leprae | Probable two-component sensor kinase | 0.0338 | 0.1715 | 0.1967 |
Brugia malayi | bHLH-PAS transcription factor | 0.0085 | 0.0374 | 0.0368 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0263 | 0.132 | 0.132 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.008 | 0.0068 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.003 | 0.0081 | 0.0069 |
Plasmodium falciparum | heat shock protein 90, putative | 0.1028 | 0.5372 | 0.5365 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0021 | 0.0036 | 0.003 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0338 | 0.1715 | 0.1701 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0769 | 0.3998 | 0.3998 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0338 | 0.1715 | 0.181 |
Schistosoma mansoni | DNA topoisomerase II | 0.0338 | 0.1715 | 0.1709 |
Echinococcus multilocularis | insulin receptor | 0.0054 | 0.021 | 0.021 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0338 | 0.1715 | 0.181 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.004 | 0.0134 | 0.0122 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0338 | 0.1715 | 0.181 |
Giardia lamblia | GTOR | 0.005 | 0.0189 | 0.009 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.003 | 0.0081 | 0.0081 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0081 | 0.0074 |
Schistosoma mansoni | regulator of G protein signaling | 0.0021 | 0.0036 | 0.003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0134 | 0.0122 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0016 | 0.0016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.005 | 0.0189 | 0.0189 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0134 | 0.0122 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0338 | 0.1715 | 0.1709 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0385 | 0.1966 | 0.1966 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Entamoeba histolytica | DNA mismatch repair protein PMS1, putative | 0.0033 | 0.0099 | 0.0063 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.1901 | 1 | 1 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0021 | 0.0036 | 0.0036 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0081 | 0.0081 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0849 | 0.4424 | 0.4415 |
Brugia malayi | Hsp90 protein | 0.1061 | 0.5548 | 0.5545 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0134 | 0.0122 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0338 | 0.1715 | 0.2989 |
Loa Loa (eye worm) | heat shock protein 75 | 0.1061 | 0.5548 | 0.5548 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0338 | 0.1715 | 0.181 |
Schistosoma mansoni | endoplasmin | 0.1901 | 1 | 1 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0338 | 0.1715 | 0.2989 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0019 | 0.0012 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Probable two component sensor kinase | 0.0338 | 0.1715 | 0.203 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Mycobacterium tuberculosis | Possible two component sensor kinase | 0.0338 | 0.1715 | 0.203 |
Leishmania major | protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Schistosoma mansoni | axis inhibition protein axin | 0.0021 | 0.0036 | 0.003 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0081 | 0.0081 |
Mycobacterium ulcerans | putative regultory protein | 0.0338 | 0.1715 | 0.181 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.005 | 0.0189 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1715 | 0.1715 |
Trichomonas vaginalis | mismatch repair protein Mlh1B (mutL homolog) | 0.0033 | 0.0099 | 0.0087 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0021 | 0.0036 | 0.0036 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0081 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0036 | 0.003 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0338 | 0.1715 | 0.181 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0376 | 0.1919 | 0.1913 |
Echinococcus multilocularis | geminin | 0.0376 | 0.1919 | 0.1919 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0006 | 0.0006 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0063 | 0.0256 | 0.0256 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0449 | 0.2301 | 0.2674 |
Treponema pallidum | heat shock protein 90 | 0.1596 | 0.8384 | 1 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0338 | 0.1715 | 0.1701 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0017 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0099 | 0.0099 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0024 | 0.0049 | 0.0037 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1705 |
Trichomonas vaginalis | heat shock protein, putative | 0.1154 | 0.604 | 0.6035 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0402 | 0.0396 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0016 | 0.0009 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0016 | 0.0016 |
Schistosoma mansoni | DNA mismatch repair protein MLH1 | 0.0033 | 0.0099 | 0.0093 |
Plasmodium falciparum | DNA mismatch repair protein PMS1, putative | 0.0033 | 0.0099 | 0.0083 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0338 | 0.1715 | 0.1709 |
Brugia malayi | hypoxia-induced factor 1 | 0.0356 | 0.1808 | 0.1803 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0241 | 0.0226 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0338 | 0.1715 | 0.203 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0021 | 0.0036 | 0.0036 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.0256 | 0.024 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0081 | 0.0074 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0548 | 0.0542 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0036 | 0.003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0081 | 0.0069 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0021 | 0.0036 | 0.0024 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0338 | 0.1715 | 0.1701 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0081 | 0.0074 |
Plasmodium vivax | endoplasmin, putative | 0.1901 | 1 | 1 |
Echinococcus multilocularis | DNA mismatch repair protein Mlh1 | 0.0033 | 0.0099 | 0.0099 |
Mycobacterium tuberculosis | Two component sensor kinase [second part] | 0.0338 | 0.1715 | 0.203 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0338 | 0.1715 | 0.203 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0081 | 0.0074 |
Trichomonas vaginalis | heat shock protein, putative | 0.1596 | 0.8384 | 0.8382 |
Toxoplasma gondii | heat shock protein 75, putative | 0.1061 | 0.5548 | 0.5541 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0016 | 0.0009 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.1596 | 0.8384 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Plasmodium vivax | hypothetical protein, conserved | 0.0338 | 0.1715 | 0.1701 |
Echinococcus granulosus | expressed protein | 0.0416 | 0.2127 | 0.2127 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.001 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.003 | 0.0081 | 0.0081 |
Onchocerca volvulus | 0.0085 | 0.0374 | 0.0537 | |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1701 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0006 | 0.0006 |
Schistosoma mansoni | regulator of G protein signaling | 0.0021 | 0.0036 | 0.003 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0071 | 0.0059 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0006 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0016 | 0.0009 |
Onchocerca volvulus | 0.003 | 0.0082 | 0.0003 | |
Brugia malayi | Protein kinase domain containing protein | 0.0054 | 0.021 | 0.0204 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0081 | 0.0074 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0216 | 0.021 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | single minded 2 | 0.0085 | 0.0374 | 0.0374 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0036 | 0.003 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.003 | 0.0081 | 0.0081 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0071 | 0.0055 |
Schistosoma mansoni | regulator of G protein signaling | 0.0021 | 0.0036 | 0.003 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0021 | 0.0036 | 0.0036 |
Brugia malayi | PXA domain containing protein | 0.0021 | 0.0036 | 0.003 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0391 | 0.0385 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0082 | 0.007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0081 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Echinococcus multilocularis | musashi | 0.003 | 0.0082 | 0.0082 |
Trichomonas vaginalis | heat shock protein, putative | 0.1563 | 0.8208 | 0.8206 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.005 | 0.0189 | 0.0182 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.004 | 0.0134 | 0.0122 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0338 | 0.1715 | 0.1709 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.0256 | 0.0256 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0338 | 0.1715 | 0.1705 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0021 | 0.0036 | 0.003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0189 | 0.0177 |
Schistosoma mansoni | lamin | 0.003 | 0.0082 | 0.0076 |
Brugia malayi | PXA domain containing protein | 0.0021 | 0.0036 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0338 | 0.1715 | 0.195 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.003 | 0.0081 | 0.0069 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0338 | 0.1715 | 0.181 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0338 | 0.1715 | 0.203 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0006 | 0.0006 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.005 | 0.0189 | 0.0189 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.004 | 0.0134 | 0.0122 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Onchocerca volvulus | 0.003 | 0.0082 | 0.0003 | |
Schistosoma mansoni | single-minded | 0.0115 | 0.0532 | 0.0526 |
Echinococcus multilocularis | heat shock protein | 0.1901 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.0256 | 0.025 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0017 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0021 | 0.0036 | 0.0036 |
Giardia lamblia | Grp94/Hsp90 | 0.1596 | 0.8384 | 0.8368 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0338 | 0.1715 | 0.9108 |
Echinococcus multilocularis | expressed protein | 0.0416 | 0.2127 | 0.2127 |
Echinococcus granulosus | axis inhibition protein axin | 0.0021 | 0.0036 | 0.0036 |
Echinococcus granulosus | DNA mismatch repair protein Mlh1 | 0.0033 | 0.0099 | 0.0099 |
Schistosoma mansoni | tyrosine kinase | 0.0088 | 0.0391 | 0.0385 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0081 | 0.0074 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4773 |
Toxoplasma gondii | DNA mismatch repair protein, C-terminal domain-containing protein | 0.0033 | 0.0099 | 0.0083 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.003 | 0.0081 | 0.0069 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0849 | 0.4424 | 0.4415 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0021 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0081 | 0.0081 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0037 | 0.0121 | 0.0105 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0338 | 0.1715 | 0.1715 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0016 | 0.0016 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.1901 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0241 | 0.0235 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.005 | 0.0189 | 0.0177 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.0016 |
Toxoplasma gondii | corepressor complex CRC230 | 0.0033 | 0.0099 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0016 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0801 | 0.417 | 0.417 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0338 | 0.1715 | 0.203 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0071 | 0.0059 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0548 | 0.0548 |
Echinococcus granulosus | insulin receptor | 0.0054 | 0.021 | 0.021 |
Plasmodium falciparum | DNA mismatch repair protein MLH | 0.0033 | 0.0099 | 0.0083 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0121 | 0.0109 |
Entamoeba histolytica | DNA mismatch repair protein MLH1, putative | 0.0033 | 0.0099 | 0.0063 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0071 | 0.0055 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0769 | 0.3998 | 0.3998 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1715 | 0.1715 |
Echinococcus multilocularis | lamin | 0.003 | 0.0082 | 0.0082 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0016 | 0.0009 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0338 | 0.1715 | 0.1705 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0338 | 0.1715 | 0.203 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0082 | 0.0082 |
Echinococcus granulosus | heat shock protein 90 | 0.1563 | 0.8208 | 0.8208 |
Schistosoma mansoni | tyrosine kinase | 0.0167 | 0.081 | 0.0804 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0081 | 0.0069 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.009 | 0.0402 | 0.0402 |
Leishmania major | protein kinase, putative | 0.003 | 0.0081 | 0.0069 |
Trypanosoma cruzi | mismatch repair protein MLH1, putative | 0.0033 | 0.0099 | 0.0087 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.001 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0241 | 0.0235 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0081 | 0.0081 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0081 | 0.0081 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0256 | 0.025 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.003 | 0.0081 | 0.0069 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0016 | 0.0009 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.0256 | 0.025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Trichomonas vaginalis | mismatch repair protein Mlh2 (mutL homolog) | 0.0033 | 0.0099 | 0.0087 |
Schistosoma mansoni | regulator of G protein signaling | 0.0021 | 0.0036 | 0.003 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0021 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0081 | 0.0081 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0081 | 0.0074 |
Mycobacterium leprae | TWO COMPONENT SENSOR HISTIDINE KINASE PRRB | 0.0338 | 0.1715 | 0.1967 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Plasmodium falciparum | endoplasmin, putative | 0.1154 | 0.604 | 0.6033 |
Onchocerca volvulus | 0.0498 | 0.2562 | 0.454 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0134 | 0.0122 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.003 | 0.0081 | 0.0069 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0338 | 0.1715 | 0.181 |
Wolbachia endosymbiont of Brugia malayi | membrane associated signal transduction histidine kinase | 0.0338 | 0.1715 | 0.195 |
Mycobacterium ulcerans | putative regulatory protein | 0.0085 | 0.0374 | 0.0163 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0021 | 0.0036 | 0.003 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.1085 | 0.5675 | 0.567 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0081 | 0.0074 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.009 | 0.0402 | 0.0402 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0134 | 0.0122 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0338 | 0.1715 | 0.9108 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.1563 | 0.8208 | 0.8191 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0021 | 0.0036 | 0.0036 |
Schistosoma mansoni | heat shock protein | 0.1061 | 0.5548 | 0.5545 |
Plasmodium falciparum | heat shock protein 90 | 0.1901 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.009 | 0.0402 | 0.0402 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0021 | 0.0036 | 0.0036 |
Entamoeba histolytica | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.005 | 0.0189 | 0.0189 |
Echinococcus granulosus | heat shock protein | 0.1901 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0081 | 0.0081 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0081 | 0.0074 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0376 | 0.1919 | 0.1919 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.1563 | 0.8208 | 0.8208 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.003 | 0.0081 | 0.0069 |
Schistosoma mansoni | endoplasmin | 0.1901 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0081 | 0.0074 |
Trypanosoma brucei | heat shock protein 90, putative | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.0385 | 0.1966 | 0.1961 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0081 | 0.0074 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0919 | 0.4792 | 0.4785 |
Trichomonas vaginalis | set domain proteins, putative | 0.0498 | 0.2562 | 0.2553 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.005 | 0.0189 | 0.0153 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0016 | 0.0016 |
Plasmodium vivax | heat shock protein, putative | 0.0849 | 0.4424 | 0.4415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0066 | 0.0054 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0338 | 0.1715 | 0.2989 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0082 | 0.0082 |
Echinococcus granulosus | heat shock protein 90 | 0.1901 | 1 | 1 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0338 | 0.1715 | 0.1715 |
Schistosoma mansoni | survival motor neuron protein | 0.0054 | 0.0208 | 0.0202 |
Toxoplasma gondii | DNA mismatch repair protein, C-terminal domain-containing protein | 0.0033 | 0.0099 | 0.0083 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0021 | 0.0036 | 0.003 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0054 | 0.021 | 0.021 |
Trypanosoma brucei | heat shock protein, putative | 0.1901 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0006 | 0.0006 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0085 | 0.0374 | 0.0374 |
Schistosoma mansoni | DNA mismatch repair protein PMS2 | 0.0033 | 0.0099 | 0.0093 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0081 | 0.0074 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0081 | 0.0074 |
Schistosoma mansoni | tyrosine kinase | 0.0054 | 0.021 | 0.0204 |
Trichomonas vaginalis | heat shock protein, putative | 0.1596 | 0.8384 | 0.8382 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0082 | 0.007 |
Leishmania major | heat shock protein 83-1 | 0.1901 | 1 | 1 |
Brugia malayi | kinase, mitochondrial precursor | 0.0338 | 0.1715 | 0.1709 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0081 | 0.0074 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0338 | 0.1715 | 0.1705 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0081 | 0.0081 |
Schistosoma mansoni | heat shock protein | 0.1901 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0208 | 0.0202 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0338 | 0.1715 | 0.181 |
Echinococcus granulosus | MORC family CW type zinc finger protein 2B | 0.0033 | 0.0099 | 0.0099 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0368 | 0.1873 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0338 | 0.1715 | 0.1705 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0081 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.0338 | 0.1715 | 0.1705 |
Plasmodium vivax | heat shock protein 86, putative | 0.1901 | 1 | 1 |
Mycobacterium leprae | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 | 0.0338 | 0.1715 | 0.1967 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0082 | 0.0076 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0071 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0123 | 0.0117 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.003 | 0.0081 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0016 | 0.0009 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0338 | 0.1715 | 0.1705 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0256 | 0.025 |
Leishmania major | mismatch repair protein PMS1, putative,mismatch repair protein | 0.0033 | 0.0099 | 0.0087 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0021 | 0.0036 | 0.0036 |
Trichomonas vaginalis | mismatch repair protein Mlh3 (mutL homolog) | 0.0033 | 0.0099 | 0.0087 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0016 | 0.001 |
Trypanosoma brucei | mismatch repair protein MLH1 | 0.0033 | 0.0099 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0216 | 0.0216 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.003 | 0.0081 | 0.0069 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0081 | 0.0074 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0081 | 0.0081 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0036 | 0.0024 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0356 | 0.1808 | 0.1808 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.0016 | 0.0004 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0081 | 0.0081 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0081 | 0.0081 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0769 | 0.3998 | 0.3995 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0081 | 0.0074 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0081 | 0.0081 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0054 | 0.0208 | 0.0202 |
Trypanosoma cruzi | mismatch repair protein PMS1, putative | 0.0033 | 0.0099 | 0.0087 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.1563 | 0.8208 | 0.8206 |
Leishmania major | heat shock protein, putative | 0.1061 | 0.5548 | 0.5542 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 20 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 40 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 80 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 160 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 20 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 40 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 80 mg/kg | ChEMBL. | 15582413 |
Survival time (functional) | > 60 day | In vivo antimalarial activity of compound against Plasmodium berghei in mice expressed as mean survival time at 160 mg/kg | ChEMBL. | 15582413 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.