Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0141 | 0.1852 | 0.2997 |
Brugia malayi | polk-prov protein | 0.0006 | 0.0033 | 0.0033 |
Echinococcus granulosus | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Brugia malayi | MH1 domain containing protein | 0.0005 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0746 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0589 | 0.0589 |
Echinococcus granulosus | smad | 0.0008 | 0.0063 | 0.0063 |
Brugia malayi | Sugar transporter family protein | 0.0455 | 0.6086 | 0.6086 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0716 | 0.9598 | 0.9598 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.017 | 0.0227 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0455 | 0.6086 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0351 | 0.0351 |
Brugia malayi | Protein kinase domain containing protein | 0.0093 | 0.1197 | 0.1197 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0093 | 0.1197 | 0.3097 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0746 | 1 | 0.5 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0716 | 0.9598 | 0.9598 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.1619 | 0.1619 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0093 | 0.1197 | 0.3097 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Onchocerca volvulus | 0.003 | 0.0351 | 0.432 | |
Echinococcus granulosus | Sugar transporter ERD6 protein | 0.0064 | 0.0812 | 0.0812 |
Schistosoma mansoni | glucose transport protein | 0.0455 | 0.6086 | 0.6086 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0063 | 0.0063 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0285 | 0.3792 | 0.6211 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0351 | 0.0351 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0135 | 0.0272 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0072 | 0.0072 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0141 | 0.1852 | 0.484 |
Echinococcus multilocularis | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Schistosoma mansoni | hypothetical protein | 0.0455 | 0.6086 | 0.6086 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma cruzi | glucose transporter, putative | 0.0064 | 0.0812 | 0.2072 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Plasmodium vivax | sugar transporter, putative | 0.0064 | 0.0812 | 0.1287 |
Trypanosoma brucei | glucose transporter 1E | 0.0141 | 0.1852 | 0.484 |
Echinococcus granulosus | dual specificity | 0.0093 | 0.1197 | 0.1197 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | nuclear factor I | 0.0005 | 0.0012 | 0.0012 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0063 | 0.0063 |
Mycobacterium ulcerans | fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT | 0.0064 | 0.0812 | 0.0782 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0103 | 0.1332 | 0.2425 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0374 | 0.0374 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0063 | 0.0063 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0746 | 1 | 1 |
Schistosoma mansoni | dihydrofolate reductase | 0.0746 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0093 | 0.1197 | 0.1197 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0086 | 0.1104 | 0.1928 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.017 | 0.0365 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0812 | 0.1277 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0064 | 0.0812 | 0.1287 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0716 | 0.9598 | 0.9598 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0093 | 0.1197 | 0.213 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0374 | 0.0374 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0063 | 0.0063 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0006 | 0.0033 | 0.0033 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0285 | 0.3792 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0219 | 0.0219 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Plasmodium falciparum | major facilitator superfamily domain-containing protein, putative | 0.0064 | 0.0812 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Plasmodium vivax | hexose transporter | 0.0455 | 0.6086 | 1 |
Trypanosoma brucei | glucose transporter 2A | 0.0141 | 0.1852 | 0.484 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0589 | 0.0589 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus granulosus | synaptic vesicle 2 protein | 0.0064 | 0.0812 | 0.0812 |
Entamoeba histolytica | protein kinase, putative | 0.0093 | 0.1197 | 0.213 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0219 | 0.0296 |
Trichomonas vaginalis | sugar transporter, putative | 0.0141 | 0.1852 | 0.2997 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0093 | 0.1197 | 0.3097 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Wolbachia endosymbiont of Brugia malayi | major facilitator superfamily permease | 0.0064 | 0.0812 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Mycobacterium ulcerans | sugar-transport integral membrane protein SugI | 0.0064 | 0.0812 | 0.0782 |
Echinococcus granulosus | dihydrofolate reductase | 0.0746 | 1 | 1 |
Toxoplasma gondii | sugar transporter ST3 | 0.0064 | 0.0812 | 0.1287 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0063 | 0.0063 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0064 | 0.0812 | 0.0812 |
Entamoeba histolytica | protein kinase, putative | 0.0093 | 0.1197 | 0.213 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0135 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.1197 | 0.1197 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0063 | 0.0063 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0219 | 0.0495 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Giardia lamblia | Hexose transporter | 0.0064 | 0.0812 | 0.1631 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0063 | 0.0063 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0049 | 0.0049 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0285 | 0.3792 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0073 | 0.0073 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0219 | 0.0495 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma cruzi | hexose transporter, putative | 0.0064 | 0.0812 | 0.2072 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0063 | 0.0063 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus granulosus | General substrate transporter | 0.0391 | 0.5223 | 0.5223 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0063 | 0.0063 |
Brugia malayi | Smad1 | 0.0008 | 0.0063 | 0.0063 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | sugar transporter | 0.0064 | 0.0812 | 0.0812 |
Mycobacterium tuberculosis | Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) | 0.0064 | 0.0812 | 0.0653 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0135 | 0.0272 |
Echinococcus multilocularis | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0285 | 0.3792 | 0.6211 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0219 | 0.0219 |
Brugia malayi | major facilitator superfamily protein | 0.0064 | 0.0812 | 0.0812 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0219 | 0.0495 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0746 | 1 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0219 | 0.0219 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Brugia malayi | MH1 domain containing protein | 0.0005 | 0.0012 | 0.0012 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Echinococcus multilocularis | Sugar transporter ERD6 protein | 0.0064 | 0.0812 | 0.0812 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0219 | 0.0219 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0219 | 0.0219 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.071 | 0.1119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0141 | 0.1852 | 0.2997 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0219 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1191 | 0.1191 |
Schistosoma mansoni | glucose transport protein | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0219 | 0.0495 |
Schistosoma mansoni | sugar transporter | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0219 | 0.0219 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0049 | 0.0049 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0219 | 0.0187 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Echinococcus multilocularis | dual specificity | 0.0093 | 0.1197 | 0.1197 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1191 | 0.1191 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0219 | 0.0219 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.017 | 0.017 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0219 | 0.0219 |
Brugia malayi | Sugar transporter family protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0063 | 0.0063 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0219 | 0.0495 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0285 | 0.3792 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0219 | 0.0219 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0219 | 0.039 |
Echinococcus granulosus | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0219 | 0.0219 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0589 | 0.0589 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0361 | 0.481 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Brugia malayi | Sugar transporter family protein | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.1619 | 0.1619 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma cruzi | hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0093 | 0.1197 | 0.3097 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Plasmodium falciparum | hexose transporter | 0.0455 | 0.6086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0374 | 0.0374 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0589 | 0.0589 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma cruzi | hexose transporter, putative | 0.0077 | 0.0989 | 0.2544 |
Mycobacterium tuberculosis | Probable conserved integral membrane transport protein | 0.0064 | 0.0812 | 0.0653 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | sugar transporter, putative | 0.0141 | 0.1852 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Echinococcus multilocularis | synaptic vesicle 2 protein | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0589 | 0.0589 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0219 | 0.0495 |
Leishmania major | myo-inositol/proton symporter (MIT) | 0.0064 | 0.0812 | 0.2072 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Trichomonas vaginalis | glucose transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Trichomonas vaginalis | sugar transport protein, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0589 | 0.0589 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0746 | 1 | 0.5 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0746 | 1 | 1 |
Loa Loa (eye worm) | sugar transporter | 0.0064 | 0.0812 | 0.0812 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0012 | 0.0012 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0063 | 0.0063 |
Leishmania major | glucose transporter, lmgt1 | 0.0141 | 0.1852 | 0.484 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Entamoeba histolytica | hypothetical protein | 0.0103 | 0.1332 | 0.2425 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0351 | 0.0351 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0812 | 0.1277 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0219 | 0.005 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0219 | 0.0495 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0455 | 0.6086 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0049 | 0.0049 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0219 | 0.0296 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Onchocerca volvulus | Putative transporter | 0.0064 | 0.0812 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.017 | 0.0227 |
Schistosoma mansoni | sugar transporter | 0.0064 | 0.0812 | 0.0812 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | smad | 0.0008 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0063 | 0.0063 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Toxoplasma gondii | sugar transporter ST1 | 0.0064 | 0.0812 | 0.1287 |
Schistosoma mansoni | glucose transporter | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Toxoplasma gondii | sugar transporter ST2 | 0.0064 | 0.0812 | 0.1287 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0063 | 0.0063 |
Schistosoma mansoni | smad | 0.0008 | 0.0063 | 0.0063 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Leishmania major | glucose transporter, lmgt2 | 0.0141 | 0.1852 | 0.484 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0589 | 0.0589 |
Mycobacterium ulcerans | integral membrane transport protein | 0.0064 | 0.0812 | 0.0782 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0063 | 0.0063 |
Trichomonas vaginalis | myo-inositol transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | glucose transport protein | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.017 | 0.0365 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0049 | 0.0049 |
Echinococcus granulosus | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Trichomonas vaginalis | sugar transporter, putative | 0.0141 | 0.1852 | 0.2997 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Giardia lamblia | Sugar-proton symporter | 0.0064 | 0.0812 | 0.1631 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0589 | 0.0589 |
Trichomonas vaginalis | glucose transporter, putative | 0.0141 | 0.1852 | 0.2997 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0049 | 0.0049 |
Leishmania major | glucose transporter, lmgt3 | 0.0141 | 0.1852 | 0.484 |
Trypanosoma cruzi | hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Leishmania major | hypothetical protein, conserved | 0.0064 | 0.0812 | 0.2072 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0086 | 0.1104 | 0.1928 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.017 | 0.017 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0455 | 0.6086 | 0.6086 |
Trypanosoma cruzi | sugar transporter, putative | 0.0064 | 0.0812 | 0.2072 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0374 | 0.0374 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Giardia lamblia | DNA repair protein RAD52 | 0.0361 | 0.481 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0589 | 0.0589 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0219 | 0.0495 |
Trichomonas vaginalis | glucose transporter, putative | 0.0141 | 0.1852 | 0.2997 |
Loa Loa (eye worm) | major facilitator superfamily transporter | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0135 | 0.0272 |
Loa Loa (eye worm) | sugar transporter | 0.0455 | 0.6086 | 0.6086 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.017 | 0.0227 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0812 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0033 | 0.0033 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Echinococcus multilocularis | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Mycobacterium ulcerans | sugar transporter | 0.0064 | 0.0812 | 0.0782 |
Echinococcus multilocularis | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.017 | 0.0227 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Brugia malayi | major facilitator superfamily protein | 0.0064 | 0.0812 | 0.0812 |
Trypanosoma brucei | sugar transporter, putative | 0.0064 | 0.0812 | 0.2072 |
Loa Loa (eye worm) | major facilitator superfamily transporter | 0.0064 | 0.0812 | 0.0812 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0063 | 0.0063 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.017 | 0.0365 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1104 | 0.1104 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.017 | 0.0365 |
Echinococcus multilocularis | General substrate transporter | 0.0391 | 0.5223 | 0.5223 |
Trypanosoma cruzi | hexose transporter | 0.0141 | 0.1852 | 0.484 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.017 | 0.0365 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0135 | 0.0272 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0219 | 0.0187 |
Echinococcus granulosus | solute carrier family 22 | 0.0064 | 0.0812 | 0.0812 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0064 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.1619 | 0.1619 |
Trypanosoma cruzi | hexose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0285 | 0.3792 | 0.6211 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0219 | 0.005 |
Trypanosoma brucei | glucose transporter, putative | 0.0141 | 0.1852 | 0.484 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0064 | 0.0812 | 0.1277 |
Brugia malayi | Dihydrofolate reductase | 0.0746 | 1 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Schistosoma mansoni | nuclear transcription factor X-box binding 1 (nfx1) | 0.0064 | 0.0812 | 0.0812 |
Entamoeba histolytica | hypothetical protein | 0.0093 | 0.1197 | 0.213 |
Schistosoma mansoni | sugar transporter | 0.0064 | 0.0812 | 0.0812 |
Trichomonas vaginalis | sugar transporter, putative | 0.0064 | 0.0812 | 0.1277 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0801 | 0.0801 |
Trypanosoma brucei | myo-inositol/proton symporter (MIT) | 0.0064 | 0.0812 | 0.2072 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0219 | 0.0219 |
Onchocerca volvulus | 0.0064 | 0.0812 | 1 | |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0812 | 0.0812 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 6.25 ug ml-1 | Minimum inhibitory concentration against methicillin-resistant Staphylococcus aureus | ChEMBL. | 11755337 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.