Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0157 | 0.3217 | 0.3117 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0174 | 0.4075 | 0.3987 |
Echinococcus multilocularis | insulin receptor | 0.0094 | 0.0145 | 0.0145 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0174 | 0.4075 | 0.3987 |
Schistosoma mansoni | tyrosine kinase | 0.0157 | 0.3217 | 0.3117 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0174 | 0.4075 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0094 | 0.0145 | 0.0145 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0174 | 0.4075 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0159 | 0.3299 | 0.32 |
Schistosoma mansoni | tyrosine kinase | 0.0295 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0174 | 0.4075 | 0.5 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0174 | 0.4075 | 0.4075 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0295 | 1 | 1 |
Leishmania major | 0.0174 | 0.4075 | 0.5 | |
Echinococcus granulosus | epidermal growth factor receptor | 0.0159 | 0.3299 | 0.32 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0174 | 0.4075 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0159 | 0.3299 | 0.32 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0174 | 0.4075 | 0.3987 |
Schistosoma mansoni | tyrosine kinase | 0.0157 | 0.3217 | 0.3117 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0174 | 0.4075 | 0.3987 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0295 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0159 | 0.3299 | 0.3299 |
Schistosoma mansoni | tyrosine kinase | 0.0159 | 0.3299 | 0.32 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0295 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 480.5 mg l-1 | Eliciting activity of the compound on Tc(taxuyunnanine C) production in cell cultures of Taxus chinensis | ChEMBL. | 15324902 |
Activity (functional) | = 38.22 mg/g DW | Eliciting activity of the compound on Tc(taxuyunnanine C) content in cell cultures of Taxus chinensis | ChEMBL. | 15324902 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.