Detailed information for compound 324533

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 599.692 | Formula: C30H35F2N5O4S
  • H donors: 3 H acceptors: 4 LogP: 2.64 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(Nc1cccc(c1)NS(=O)(=O)C)CN1CCN([C@H](C1)Cc1ccccc1)C(=O)C[C@@H](Cc1ccc(c(c1)F)F)N
  • InChi: 1S/C30H35F2N5O4S/c1-42(40,41)35-25-9-5-8-24(18-25)34-29(38)20-36-12-13-37(26(19-36)15-21-6-3-2-4-7-21)30(39)17-23(33)14-22-10-11-27(31)28(32)16-22/h2-11,16,18,23,26,35H,12-15,17,19-20,33H2,1H3,(H,34,38)/t23-,26+/m1/s1
  • InChiKey: PUKARVRQDSPFPB-BVAGGSTKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dipeptidyl-peptidase 7 Starlite/ChEMBL References
Homo sapiens dipeptidyl-peptidase 4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog Get druggable targets OG5_128614 All targets in OG5_128614
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma japonicum ko:K01276 dipeptidyl-peptidase II [EC3.4.14.2], putative Get druggable targets OG5_139351 All targets in OG5_139351
Echinococcus granulosus dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614
Brugia malayi prolyl oligopeptidase family protein Get druggable targets OG5_128614 All targets in OG5_128614
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma japonicum ko:K01278 dipeptidyl-peptidase 4, putative Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma mansoni family S28 unassigned peptidase (S28 family) Get druggable targets OG5_139351 All targets in OG5_139351
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase Get druggable targets OG5_139351 All targets in OG5_139351
Echinococcus granulosus Lysosomal Pro X carboxypeptidase Get druggable targets OG5_139351 All targets in OG5_139351
Loa Loa (eye worm) prolyl oligopeptidase Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) Get druggable targets OG5_128614 All targets in OG5_128614
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi serine carboxypeptidase S28, putative dipeptidyl-peptidase 7 492 aa 471 aa 25.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus acylamino acid releasing enzyme 0.0017 0.008 0.0079
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.008 0.0506
Loa Loa (eye worm) flap endonuclease-1 0.0082 0.0848 0.1666
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0315 0.0915
Mycobacterium tuberculosis Conserved protein 0.0036 0.0315 0.0915
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0315 0.0915
Treponema pallidum NADH oxidase 0.0032 0.0265 0.5
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0353 0.321
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0089 0.0626
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0265 0.2416
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0146 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1098 1
Brugia malayi C1-like domain containing protein 0.001 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0356 0.0698
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.1469 0.1468
Echinococcus granulosus transcription factor btf3 0.0034 0.0283 0.0283
Brugia malayi prolyl oligopeptidase family protein 0.0209 0.2359 0.4635
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0353 0.1057
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1098 0.2157
Echinococcus multilocularis expressed protein 0.0032 0.0266 0.0265
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0265 0.0265
Schistosoma mansoni hypothetical protein 0.0037 0.0322 0.0321
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Entamoeba histolytica exonuclease, putative 0.0017 0.008 0.0505
Echinococcus multilocularis protein dispatched 1 0.0047 0.0435 0.0434
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0451 0.4419
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.008 0.0506
Echinococcus multilocularis N chimaerin 0.001 0.0002 0.0001
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0451 0.1438
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0265 0.2416
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0159 0.3999
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1098 0.1098
Schistosoma mansoni hypothetical protein 0.0039 0.0349 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0159 0.031
Giardia lamblia Kinase, PLK 0.0103 0.1098 1
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.007 0.0716 0.652
Loa Loa (eye worm) hypothetical protein 0.0054 0.0525 0.103
Schistosoma mansoni transcription factor LCR-F1 0.011 0.118 0.1179
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0156
Leishmania major hypothetical protein, conserved 0.0019 0.0104 0.095
Echinococcus multilocularis transcription factor btf3 0.0034 0.0283 0.0283
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0353 0.321
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0159 0.031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1469 0.1468
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0315 0.0315
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0025 0.0174 0.1063
Brugia malayi beta-NAC-like protein 0.0034 0.0283 0.0556
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0078 0.0811 0.0811
Plasmodium vivax exonuclease I, putative 0.0017 0.008 0.0529
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0017 0.008 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1098 0.1098
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2855 0.2854
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Plasmodium vivax ERCC1 nucleotide excision repair protein, putative 0.0053 0.0512 0.5052
Trypanosoma brucei unspecified product 0.0027 0.0207 0.1886
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0356 0.0355
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1098 1
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0257 0.1567
Schistosoma mansoni exonuclease 0.0017 0.008 0.0079
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.008 0.0079
Giardia lamblia DINP protein human, muc B family 0.004 0.0353 0.3023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0456 0.5282 0.5282
Schistosoma mansoni hypothetical protein 0.0017 0.0087 0.0086
Trichomonas vaginalis excision repair cross-complementing 1 ercc1, putative 0.0053 0.0512 0.4617
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0649 0.5907
Schistosoma mansoni rac gtpase activating protein 0.0072 0.0736 0.0735
Echinococcus granulosus muscleblind protein 0.0144 0.1591 0.159
Mycobacterium leprae Probable lipase LipE 0.0036 0.0315 0.0907
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Plasmodium vivax DNA repair protein RAD2, putative 0.0017 0.008 0.0529
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.007 0.0716 0.652
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0017 0.008 0.1569
Schistosoma mansoni kinase 0.0052 0.0501 0.05
Leishmania major oligopeptidase b 0.0017 0.008 0.0729
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0265 0.7301
Entamoeba histolytica hypothetical protein 0.011 0.118 0.7507
Onchocerca volvulus DNA ligase 3 homolog 0.0019 0.0104 0.0204
Brugia malayi hypothetical protein 0.0019 0.0113 0.0222
Echinococcus granulosus cpg binding protein 0.0059 0.0583 0.0582
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Brugia malayi hypothetical protein 0.0036 0.031 0.0608
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.008 0.065
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0034 0.0226
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0236 0.2675 1
Echinococcus multilocularis prolyl endopeptidase 0.0017 0.008 0.0079
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0451 0.0451
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Entamoeba histolytica DNA excision repair protein, putative 0.0053 0.0512 0.3254
Loa Loa (eye worm) hypothetical protein 0.0144 0.1591 0.3126
Trypanosoma cruzi trypanothione reductase, putative 0.0093 0.0984 0.8965
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0353 0.3153
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.008 0.0728
Echinococcus multilocularis thioredoxin glutathione reductase 0.0093 0.0984 0.0984
Trypanosoma brucei unspecified product 0.0027 0.0207 0.1886
Trypanosoma cruzi oligopeptidase b 0.0017 0.008 0.0729
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0082 0.0848 0.7724
Entamoeba histolytica hypothetical protein 0.011 0.118 0.7507
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0257 0.2337
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0283 0.2519
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0353 0.321
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0451 0.0451
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0265 0.2353
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0236 0.2675 1
Giardia lamblia Serine peptidase, putative 0.0025 0.0174 0.1354
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0025 0.0174 0.1104
Schistosoma mansoni DNA polymerase eta 0.0064 0.0644 0.0643
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0002 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0729
Plasmodium vivax glutathione reductase, putative 0.0093 0.0984 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0064 0.0644 0.1264
Loa Loa (eye worm) hypothetical protein 0.0025 0.0174 0.0341
Mycobacterium tuberculosis Probable dehydrogenase 0.0212 0.2394 0.8921
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0029 0.0268
Echinococcus granulosus dna polymerase kappa 0.004 0.0353 0.0352
Echinococcus granulosus protein kinase c epsilon type 0.001 0.0005 0.0004
Schistosoma mansoni cpg binding protein 0.0059 0.0583 0.0582
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.032 0.1957
Loa Loa (eye worm) hypothetical protein 0.0041 0.0367 0.072
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0039 0.0349 0.0349
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0078 0.0811 0.7387
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0257 0.1629
Schistosoma mansoni hypothetical protein 0.0855 1 1
Toxoplasma gondii thioredoxin reductase 0.0093 0.0984 0.6011
Schistosoma mansoni excision repair cross-complementing 1 ercc1 0.0053 0.0512 0.0511
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0367 0.0366
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0315 0.0619
Leishmania major DNA repair protein, putative 0.0019 0.0104 0.095
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0315 0.8852
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0367 0.0366
Brugia malayi protein kinase C3,putative 0.001 0.0005 0.0008
Loa Loa (eye worm) prolyl oligopeptidase 0.0017 0.008 0.0156
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0025 0.0174 0.1104
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0212 0.2394 0.8921
Plasmodium falciparum thioredoxin reductase 0.0093 0.0984 1
Schistosoma mansoni hypothetical protein 0.0017 0.0087 0.0086
Brugia malayi Thioredoxin reductase 0.0093 0.0984 0.1934
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0017 0.008 0.0079
Schistosoma mansoni hypothetical protein 0.0039 0.0349 0.0349
Schistosoma mansoni patched 1 0.0041 0.0367 0.0366
Schistosoma mansoni hypothetical protein 0.0017 0.0087 0.0086
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0315 0.2813
Plasmodium vivax hypothetical protein, conserved 0.0017 0.008 0.0531
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1098 0.1098
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0029 0.0268
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0265 0.2416
Echinococcus granulosus exonuclease 1 0.0017 0.008 0.0079
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0068 0.0686 0.0685
Loa Loa (eye worm) hypothetical protein 0.0025 0.0174 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0005 0.0004
Brugia malayi Serine carboxypeptidase S28 family protein 0.0025 0.0174 0.0341
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2855 0.2854
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0159 0.0311
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.007 0.0716 0.652
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0025 0.0174 0.1585
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Onchocerca volvulus 0.044 0.5088 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.118 0.1179
Echinococcus granulosus tankyrase 0.0011 0.0009 0.0008
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.007 0.0716 0.4372
Schistosoma mansoni cpg binding protein 0.0056 0.0545 0.0544
Brugia malayi RNA recognition motif domain containing protein 0.0251 0.2855 0.561
Loa Loa (eye worm) tnks protein 0.0011 0.0009 0.0017
Brugia malayi WGR domain containing protein 0.0143 0.1572 0.3088
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0526 0.0526
Brugia malayi hypothetical protein 0.011 0.118 0.2318
Schistosoma mansoni hypothetical protein 0.0796 0.9296 0.9296
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0265 0.0265
Schistosoma mansoni rab6-interacting 0.0019 0.0113 0.0113
Leishmania major DNA polymerase eta, putative 0.0064 0.0644 0.5861
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0353 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0265 0.0265
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.008 0.0506
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0644 0.5861
Echinococcus multilocularis geminin 0.0855 1 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0315 0.2813
Loa Loa (eye worm) hypothetical protein 0.0023 0.0159 0.031
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0649 0.1274
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.0156 0.1417
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0164 0.0321
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0257 0.2337
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0451 0.2756
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0113 0.0113
Entamoeba histolytica DNA-repair protein, putative 0.0017 0.008 0.0505
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1098 0.2157
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0356 0.0698
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0134 0.1469 0.2886
Toxoplasma gondii histone lysine methyltransferase SET1 0.0106 0.1136 0.6936
Brugia malayi Flap endonuclease-1 0.0082 0.0848 0.1666
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Toxoplasma gondii prolyl endopeptidase 0.0017 0.008 0.0489
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Echinococcus multilocularis DNA excision repair protein ERCC 1 0.0053 0.0512 0.0511
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0266 0.2355
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0156
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0056
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0353 0.321
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0545 0.107
Entamoeba histolytica zinc finger protein, putative 0.0011 0.0009 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.1419 0.2787
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0089 0.185
Plasmodium falciparum DNA repair endonuclease, putative 0.0033 0.0276 0.2582
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0265 0.162
Loa Loa (eye worm) hypothetical protein 0.044 0.5088 1
Brugia malayi Doublecortin family protein 0.0019 0.0113 0.0222
Brugia malayi Helix-hairpin-helix motif family protein 0.003 0.024 0.0471
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.118 0.1179
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0353 0.224
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0159 0.3999
Trichomonas vaginalis flap endonuclease-1, putative 0.0082 0.0848 0.7705
Entamoeba histolytica hypothetical protein 0.0022 0.0146 0.0926
Trypanosoma brucei DNA polymerase eta, putative 0.0064 0.0644 0.5861
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0143 0.1572 1
Toxoplasma gondii hypothetical protein 0.0017 0.008 0.0489
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.1009 0.1008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0087 0.0169
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0485 0.437
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.008 0.0156
Echinococcus multilocularis expressed conserved protein 0.0089 0.0941 0.094
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0451 0.2756
Echinococcus multilocularis acylamino acid releasing enzyme 0.0017 0.008 0.0079
Trichomonas vaginalis helicase, putative 0.0013 0.0034 0.0226
Loa Loa (eye worm) glutathione reductase 0.0093 0.0984 0.1934
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.001 0.0005 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0048 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0353 0.0692
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1469 0.1468
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0283 0.266
Brugia malayi Muscleblind-like protein 0.0144 0.1591 0.3126
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.008 0.065
Echinococcus multilocularis flap endonuclease GEN 1 0.0017 0.008 0.0079
Brugia malayi TAR-binding protein 0.0251 0.2855 0.561
Schistosoma mansoni transcription factor btf3 0.0034 0.0283 0.0283
Schistosoma mansoni hypothetical protein 0.011 0.118 0.1179
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0174
Plasmodium falciparum thioredoxin reductase 0.0032 0.0265 0.247
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0087 0.0169
Schistosoma mansoni polycystin 1-related 0.0019 0.0113 0.0113
Onchocerca volvulus 0.0019 0.0113 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0283 0.2519
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Brugia malayi Tnks protein 0.0011 0.0009 0.0017
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0265 1
Schistosoma mansoni hypothetical protein 0.0855 1 1
Onchocerca volvulus 0.0025 0.0174 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Echinococcus granulosus DNA excision repair protein ERCC 1 0.0053 0.0512 0.0511
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0113 0.0113
Brugia malayi glutathione reductase 0.0093 0.0984 0.1934
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0048 0.0047
Loa Loa (eye worm) TAR-binding protein 0.0251 0.2855 0.561
Schistosoma mansoni lipoxygenase 0.0054 0.0526 0.0526
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0119 0.1286 0.1285
Toxoplasma gondii ERCC4 domain-containing protein 0.0038 0.033 0.2016
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0265 0.2416
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0002 0.0001
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0019 0.0104 0.095
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0113 0.0222
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0265 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0005 0.0004
Brugia malayi beta-lactamase 0.0036 0.0315 0.0619
Onchocerca volvulus Tankyrase homolog 0.0011 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0174
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0266 0.0521
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0029 0.0179
Schistosoma mansoni hypothetical protein 0.0019 0.0113 0.0113
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0451 0.4111
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0265 0.247
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0327 0.0326
Trypanosoma brucei oligopeptidase b 0.0017 0.008 0.0729
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0072 0.0736 0.1445
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.001 0.0005 0.0004
Plasmodium falciparum glutathione reductase 0.0093 0.0984 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0525 0.103
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0174 0.1514
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0367 0.3283
Entamoeba histolytica hypothetical protein 0.0034 0.0283 0.18
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.1469 0.1468
Loa Loa (eye worm) hypothetical protein 0.0019 0.0104 0.0204
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.008 0.065
Toxoplasma gondii DNA repair protein rad10 subfamily protein 0.0053 0.0512 0.3126
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0017 0.008 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0113 0.0113
Entamoeba histolytica hypothetical protein 0.011 0.118 0.7507
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0315 0.2872
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0159 0.3999
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0025 0.0174 0.1585
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0315 0.0915
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0029 0.0268
Echinococcus multilocularis dna repair endonuclease xpf 0.0038 0.033 0.033
Leishmania major trypanothione reductase 0.0093 0.0984 0.8965
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0169
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0029 0.0268
Plasmodium falciparum glutathione reductase 0.0032 0.0265 0.247
Brugia malayi beta-lactamase family protein 0.0036 0.0315 0.0619
Loa Loa (eye worm) hypothetical protein 0.0037 0.0322 0.0632
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0212 0.2394 0.892
Onchocerca volvulus 0.0036 0.0315 0.0619
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0315 0.2995
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0159 0.0303
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0209 0.2359 0.2358
Loa Loa (eye worm) hypothetical protein 0.0062 0.0619 0.1216
Plasmodium falciparum peptidase, putative 0.0017 0.008 0.0531
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0451 0.0451
Trichomonas vaginalis esterase, putative 0.0036 0.0315 0.2813
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0025 0.0174 0.0173
Giardia lamblia Alanyl dipeptidyl peptidase 0.0017 0.008 0.0474
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0159 0.0303
Leishmania major DNA polymerase kappa, putative 0.0012 0.0029 0.0268
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0356 0.0698
Plasmodium falciparum DNA repair protein RAD2, putative 0.0017 0.008 0.0529
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0356 0.3416
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0113 0.0113
Onchocerca volvulus 0.0036 0.0315 0.0619
Plasmodium falciparum exonuclease I, putative 0.0017 0.008 0.0529
Schistosoma mansoni unc-13 (munc13) 0.0016 0.007 0.0069
Leishmania major hypothetical protein, conserved 0.0036 0.0315 0.2872
Echinococcus granulosus WGR domain containing protein 0.0044 0.0408 0.0408
Echinococcus multilocularis Protein kinase C, brain isozyme 0.001 0.0005 0.0004
Plasmodium vivax DNA repair endonuclease, putative 0.0038 0.033 0.315
Echinococcus granulosus protein kinase c iota type 0.001 0.0005 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0315 0.2872
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0017 0.008 0.0079
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1098 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0265 0.2207
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0017 0.008 0.0489
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0353 0.321
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0209 0.2359 0.4635
Onchocerca volvulus Prolyl endopeptidase homolog 0.0017 0.008 0.0156
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0265 0.2416
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.001 0.0005 0.0004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0649 0.5907
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2855 0.2854
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0017 0.008 0.0079
Echinococcus granulosus prolyl endopeptidase 0.0017 0.008 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Loa Loa (eye worm) hypothetical protein 0.0095 0.1009 0.1982
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0156
Mycobacterium ulcerans hypothetical protein 0.0023 0.0159 0.3999
Brugia malayi MH2 domain containing protein 0.013 0.1419 0.2787
Giardia lamblia hypothetical protein 0.0017 0.008 0.0473
Echinococcus multilocularis protein patched 0.0041 0.0367 0.0366
Echinococcus granulosus Dipeptidyl peptidase 9 0.007 0.0716 0.0715
Plasmodium falciparum ERCC1 nucleotide excision repair protein, putative 0.0053 0.0512 0.5052
Brugia malayi hypothetical protein 0.044 0.5088 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0251 0.2855 0.561
Trypanosoma brucei DNA repair protein, putative 0.0019 0.0104 0.095
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0265 0.2353
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0315 0.8852
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0054
Schistosoma mansoni flap endonuclease-1 0.0074 0.0756 0.0755
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.008 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0207 0.1886
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2641 0.987
Schistosoma mansoni atypical protein kinase C 0.001 0.0005 0.0004
Trichomonas vaginalis rotamase, putative 0.0032 0.0257 0.2273
Echinococcus multilocularis muscleblind protein 1 0.0144 0.1591 0.159
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0034 0.0226
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0356 0.0698
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0029 0.0268
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.008 0.0079
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.008 0.065
Echinococcus granulosus RUN 0.0019 0.0113 0.0113
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0017 0.008 0.0652
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0159 0.3999
Leishmania major DNA damage repair protein, putative 0.0012 0.0029 0.0268
Giardia lamblia Exonuclease 1 0.0017 0.008 0.0473
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0283 0.2581
Loa Loa (eye worm) hypothetical protein 0.0019 0.0113 0.0222
Echinococcus multilocularis dnaJ subfamily B 0.0796 0.9296 0.9296
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0283 0.2581
Loa Loa (eye worm) prolyl oligopeptidase 0.0209 0.2359 0.4635
Echinococcus granulosus poly adp ribose polymerase 2 0.0078 0.0811 0.0811
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0353 0.0352
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0212 0.2394 0.8921
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0174
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.1009 0.6418
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0159 0.3999
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0315 0.0619
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0257 0.2337
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0164 0.0321
Loa Loa (eye worm) CAMK/PKD protein kinase 0.001 0.0005 0.0008
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0353 0.321
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0257 0.2337
Echinococcus granulosus dna polymerase eta 0.0064 0.0644 0.0643
Echinococcus multilocularis tankyrase 0.0011 0.0009 0.0008
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.008 0.0488
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0159 0.3999
Loa Loa (eye worm) hypothetical protein 0.0078 0.0811 0.1593
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0728
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0649 0.0648
Loa Loa (eye worm) histone methyltransferase 0.0017 0.0088 0.0172
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0033 0.0271 0.0271
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0025 0.0174 0.0173
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0649 0.5907
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0174 0.1514
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0174 0.0341
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0283 0.266
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0367 0.0366
Echinococcus granulosus Rac GTPase activating protein 1 0.0072 0.0736 0.0735
Giardia lamblia Alanyl dipeptidyl peptidase 0.0017 0.008 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.008 0.0652
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0048 0.0047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0087 0.0169
Toxoplasma gondii diacylglycerol kinase, putative 0.001 0.0001 0.0004
Giardia lamblia Rho GAP, putative 0.0062 0.0619 0.5519
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0649 0.1274
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0265 1
Trypanosoma cruzi prolyl endopeptidase 0.0017 0.008 0.0729
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0159 0.3999
Schistosoma mansoni rab6-interacting 0.0019 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0023 0.0159 0.031
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0025 0.0174 0.0173
Trypanosoma brucei DNA repair protein, putative 0.0023 0.0156 0.1417
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0143 0.1572 0.1571
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0017 0.008 0.0729
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0019 0.0104 0.095
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0265 0.2416
Brugia malayi Serine protease Z688.6 precursor 0.0025 0.0174 0.0341
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2855 0.2854
Brugia malayi hypothetical protein 0.0036 0.031 0.0608
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0353 0.0352
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0029 0.0268
Loa Loa (eye worm) hypothetical protein 0.0023 0.0159 0.031
Trichomonas vaginalis rotamase, putative 0.0032 0.0266 0.2355
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0265 0.2416
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.1469 0.1468
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0456 0.5282 0.5282
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0649 0.0648
Onchocerca volvulus 0.0019 0.0113 0.0222
Trypanosoma cruzi DNA repair protein, putative 0.0019 0.0104 0.095
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0048 0.0047
Onchocerca volvulus 0.0036 0.0315 0.0619
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0356 0.3416
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.001 0.0005 0.0008
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0143 0.1572 0.1571
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0029 0.0268
Trypanosoma brucei prolyl oligopeptidase, putative 0.0017 0.008 0.0729
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0356 0.2172
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0207 0.1886
Echinococcus granulosus Protein kinase C brain isozyme 0.001 0.0005 0.0004
Schistosoma mansoni DNA repair endonuclease xp-f / mei-9 / rad1 0.0038 0.033 0.033
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0649 0.5907
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0146 0.0145
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0025 0.0174 0.1585
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0113 0.088
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0159 0.1444
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0048 0.0047
Brugia malayi Protein kinase c protein 2 0.001 0.0005 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0134 0.1469 0.2886
Schistosoma mansoni hypothetical protein 0.0039 0.0349 0.0349
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0327 0.0326
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0159 0.1005
Schistosoma mansoni cpg binding protein 0.0059 0.0583 0.0582
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0025 0.0174 0.1514
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0082 0.0848 0.7724
Plasmodium vivax thioredoxin reductase, putative 0.0093 0.0984 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0159 0.031
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0283 0.0556
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0353 0.321
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0087 0.0086
Echinococcus granulosus flap endonuclease GEN 1 0.0017 0.008 0.0079
Brugia malayi RNA binding protein 0.0251 0.2855 0.561
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0156
Giardia lamblia Flap structure-specific endonuclease 0.0082 0.0848 0.7662
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0029 0.0268
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.0156 0.1417
Brugia malayi protein kinase C II. 0.001 0.0005 0.0008
Brugia malayi hypothetical protein 0.0019 0.0113 0.0222
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0526 0.0526
Loa Loa (eye worm) RNA binding protein 0.0251 0.2855 0.561
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0174
Brugia malayi XPG I-region family protein 0.0017 0.008 0.0156
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0265 0.2416
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0089 0.0043
Giardia lamblia Thymus-specific serine protease precursor 0.0025 0.0174 0.1354
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.0475 0.0933
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0315 0.0915
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1098 0.6986
Trypanosoma brucei trypanothione reductase 0.0093 0.0984 0.8965
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0266 0.0521
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Entamoeba histolytica exonuclease, putative 0.0017 0.008 0.0505
Schistosoma mansoni protein kinase C mu 0.001 0.0005 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0353 0.321
Brugia malayi RhoGAP domain containing protein 0.0072 0.0736 0.1445
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0265 0.7301
Echinococcus granulosus expressed protein 0.0032 0.0266 0.0265
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0451 0.0451
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0017 0.008 0.0506
Trypanosoma brucei prolyl endopeptidase 0.0017 0.008 0.0729
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0236 0.2675 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0525 0.103
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.032 0.2918
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0265 0.052
Trypanosoma cruzi oligopeptidase b 0.0017 0.008 0.0729
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0315 0.0907
Brugia malayi hypothetical protein 0.0054 0.052 0.1021
Echinococcus multilocularis protein kinase c epsilon type 0.001 0.0005 0.0004
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0078 0.0811 0.0811
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0451 0.0451
Onchocerca volvulus 0.0056 0.0545 0.107
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0644 0.1264
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0649 0.4125
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0207 0.1886
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Entamoeba histolytica Flap nuclease, putative 0.0082 0.0848 0.5395
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0283 0.2581
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.1419 0.2787
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0054
Echinococcus multilocularis dna polymerase eta 0.0064 0.0644 0.0643
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0408 0.0408
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0093 0.0984 0.3491
Mycobacterium tuberculosis Probable reductase 0.0212 0.2394 0.8921
Echinococcus multilocularis flap endonuclease 1 0.0082 0.0848 0.0848
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0212 0.2394 0.8921
Mycobacterium tuberculosis Conserved protein 0.0036 0.0315 0.0915
Schistosoma mansoni hypothetical protein 0.004 0.0356 0.0355
Loa Loa (eye worm) hypothetical protein 0.0109 0.1169 0.2296
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0315 0.2813
Leishmania major DNA polymerase kappa, putative 0.004 0.0353 0.321
Echinococcus granulosus thioredoxin glutathione reductase 0.0093 0.0984 0.0984
Trichomonas vaginalis exonuclease%2C+putative 0.0017 0.008 0.065
Trypanosoma brucei DNA repair protein RAD2, putative 0.0017 0.008 0.0728
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0082 0.0848 0.7724
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.001 0.0005 0.0008
Mycobacterium tuberculosis Probable oxidoreductase 0.0236 0.2675 1
Loa Loa (eye worm) ERCC4 domain-containing protein 0.0038 0.033 0.0648
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0315 0.2813
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.007 0.0716 0.652
Brugia malayi prolyl oligopeptidase family protein 0.007 0.0716 0.1406
Loa Loa (eye worm) beta-lactamase 0.0036 0.0315 0.0619
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0456 0.5282 0.5282
Schistosoma mansoni loxhd1 0.0019 0.0113 0.0113
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.008 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1098 1
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0025 0.0174 0.1514
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0315 0.0915
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0159 0.1444
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0005 0.0004
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0265 0.247
Brugia malayi RhoGAP domain containing protein 0.0062 0.0619 0.1216
Leishmania major DNA polymerase eta, putative 0.0037 0.032 0.2918
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0078 0.0811 0.7387
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0315 0.0315
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0451 0.0451
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0148 0.1638 1
Entamoeba histolytica hypothetical protein 0.011 0.118 0.7507
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1098 0.2157
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0451 0.0886
Brugia malayi CHE-14 protein 0.0041 0.0367 0.072
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Loa Loa (eye worm) hypothetical protein 0.0144 0.1591 0.3126
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0017 0.008 0.0729
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0265 0.247
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0159 0.1005
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0025 0.0174 0.1104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0113 0.0222
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0265 0.162
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.1492 0.1491
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0283 0.18
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0728
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1026 0.1026
Mycobacterium tuberculosis Conserved protein 0.0036 0.0315 0.0915
Trypanosoma brucei poly(adp-ribose) polymerase 0.0078 0.0811 0.7387
Schistosoma mansoni hypothetical protein 0.0017 0.0087 0.0086
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0265 0.2416
Echinococcus multilocularis dna polymerase kappa 0.004 0.0353 0.0352
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Entamoeba histolytica hypothetical protein, conserved 0.0017 0.008 0.0506
Loa Loa (eye worm) helix-hairpin-helix domain-containing protein family protein 0.0053 0.0512 0.1005
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0159 0.0311
Brugia malayi WGR domain containing protein 0.0078 0.0811 0.1593
Echinococcus multilocularis cpg binding protein 0.0059 0.0583 0.0582
Leishmania major hypothetical protein, conserved 0.0017 0.008 0.0728
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Schistosoma mansoni rotamase 0.0032 0.0266 0.0265
Brugia malayi RhoGAP domain containing protein 0.001 0.0002 0.0002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0367 0.072
Echinococcus granulosus N chimaerin 0.001 0.0002 0.0001
Trichomonas vaginalis nuclease Rad1 0.0038 0.033 0.2949
Leishmania major basic transcription factor 3a, putative 0.0034 0.0283 0.2581
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0451 0.4111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.1469 0.1468
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0017 0.008 0.0729
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.1009 0.1008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0087 0.0086
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0088 0.0088
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0353 0.0352
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0025 0.0174 0.1514
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0025 0.0174 0.1514
Echinococcus multilocularis exonuclease 1 0.0017 0.008 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0265 0.247
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0082 0.0848 0.5179
Echinococcus granulosus tar DNA binding protein 0.0251 0.2855 0.2854
Toxoplasma gondii ABC1 family protein 0.0036 0.0315 0.1926
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.008 0.0728
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0209 0.2359 0.2358
Loa Loa (eye worm) hypothetical protein 0.0025 0.0174 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0034 0.0226
Echinococcus granulosus dna repair endonuclease xpf 0.0038 0.033 0.033
Trypanosoma brucei exonuclease, putative 0.0017 0.008 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0005 0.0004
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0283 0.1731
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0315 0.0315
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0159 0.1005
Echinococcus multilocularis tar DNA binding protein 0.0251 0.2855 0.2854
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0451 0.4111
Brugia malayi beta-lactamase family protein 0.0036 0.0315 0.0619
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0353 0.0352
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0353 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.007 0.0716 0.652
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0485 0.437
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0451 0.0886
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0283 0.2519
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0315 0.0915
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0315 0.0915
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0017 0.008 0.0729
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0017 0.008 0.0652
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.008 0.0156
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Echinococcus granulosus flap endonuclease 1 0.0082 0.0848 0.0848
Plasmodium vivax flap endonuclease 1, putative 0.0082 0.0848 0.8574
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0322 0.0632
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0029 0.0268
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0451 0.4111
Trypanosoma brucei polo-like protein kinase 0.0103 0.1098 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0315 0.2813
Echinococcus granulosus GPCR family 2 0.0017 0.0087 0.0086
Brugia malayi isocitrate dehydrogenase 0.0048 0.0451 0.0886
Echinococcus multilocularis muscleblind protein 0.0144 0.1591 0.159
Loa Loa (eye worm) thioredoxin reductase 0.0093 0.0984 0.1934
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0265 0.0722
Echinococcus granulosus expressed conserved protein 0.0089 0.0941 0.094
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0451 0.0451
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0029 0.0268
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0029 0.0268
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0087 0.0086
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.007 0.0716 0.0715
Mycobacterium ulcerans hypothetical protein 0.0036 0.0315 0.8852
Mycobacterium tuberculosis Probable peptidase 0.0017 0.008 0.0008
Loa Loa (eye worm) RhoGAP domain-containing protein 0.001 0.0002 0.0002
Echinococcus multilocularis GPCR, family 2 0.0017 0.0087 0.0086
Echinococcus multilocularis RUN 0.0019 0.0113 0.0113
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0353 0.0692
Mycobacterium ulcerans lipase LipD 0.0036 0.0315 0.8852
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0353 0.3153
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0649 0.0648
Brugia malayi Serine protease Z688.6 precursor 0.0025 0.0174 0.0341
Brugia malayi CXXC zinc finger family protein 0.0056 0.0545 0.107
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0056 0.0549 0.1078
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0089 0.0626
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0212 0.2394 0.8921
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0086 0.0167
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0265 0.2416
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2855 0.2854
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0525 0.103
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0113 0.0113
Mycobacterium ulcerans beta-lactamase 0.0036 0.0315 0.8852
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.1009 0.1982
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.008 0.0079
Echinococcus multilocularis Rac GTPase activating protein 1 0.0072 0.0736 0.0735
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Echinococcus granulosus poly ADP ribose polymerase 1 0.0143 0.1572 0.1571
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0113 0.088
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0451 0.4419
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0017 0.008 0.0729
Loa Loa (eye worm) hypothetical protein 0.0036 0.0315 0.0619
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0034 0.0226
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0017 0.008 0.0729
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0353 0.321
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.008 0.0156
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0174
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0353 0.1057
Schistosoma mansoni lipoxygenase 0.0019 0.0113 0.0113
Loa Loa (eye worm) XPG I-region family protein 0.0017 0.008 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0315 0.2872
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.1492 0.1491
Schistosoma mansoni tankyrase 0.0011 0.0009 0.0008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0029 0.0179
Echinococcus multilocularis protein kinase c iota type 0.001 0.0005 0.0004
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.008 0.0488
Brugia malayi ERCC4 domain containing protein 0.0038 0.033 0.0648
Onchocerca volvulus 0.0023 0.0159 0.031
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0209 0.2359 0.2358
Loa Loa (eye worm) hypothetical protein 0.0054 0.052 0.1021
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0017 0.008 0.0506
Echinococcus multilocularis Dipeptidyl peptidase 9 0.007 0.0716 0.0715
Echinococcus granulosus dnaJ subfamily B 0.0796 0.9296 0.9296
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0451 0.4111
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0265 0.7301
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0017 0.008 0.0079
Entamoeba histolytica DNA repair endonuclease, putative 0.0038 0.033 0.2098
Brugia malayi polk-prov protein 0.0012 0.0029 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.1469 0.1468
Trypanosoma brucei unspecified product 0.004 0.0353 0.321
Plasmodium falciparum flap endonuclease 1 0.0082 0.0848 0.8574
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0159 0.1444
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.008 0.0729

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 280 nM Inhibitory concentration against quiescent cell proline peptidase ChEMBL. 15324904
IC50 (binding) = 280 nM Inhibitory concentration against quiescent cell proline peptidase ChEMBL. 15324904
IC50 (binding) = 1100 nM Inhibitory concentration against Dipeptidyl-peptidase IV ChEMBL. 15324904
IC50 (binding) = 1100 nM Inhibitory concentration against Dipeptidyl-peptidase IV ChEMBL. 15324904

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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