Detailed information for compound 325799

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 441.565 | Formula: C28H31N3O2
  • H donors: 2 H acceptors: 1 LogP: 4.55 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNC(=O)c1ccc(cc1)/C(=C\1/CC2CCC(C1)N2Cc1ccoc1)/c1cccc(c1)N
  • InChi: 1S/C28H31N3O2/c1-2-30-28(32)21-8-6-20(7-9-21)27(22-4-3-5-24(29)14-22)23-15-25-10-11-26(16-23)31(25)17-19-12-13-33-18-19/h3-9,12-14,18,25-26H,2,10-11,15-17,29H2,1H3,(H,30,32)
  • InChiKey: CRUVNMBAKCMMJA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus opioid receptor, mu 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable monooxygenase 0.0028 0.0006 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0005 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0006 0.0005
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0029 0.0006 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0002 0.0002
Echinococcus multilocularis transfer RNA-Lys 0.0269 0.0123 0.0123
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0226 0.0102 0.0101
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0106 0.0044 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0002 0.0033
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0004 0.0004
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0007 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.012 0.4166
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0029 0.0006 0.0006
Brugia malayi steroid hormone receptor 0.0178 0.0079 0.0079
Schistosoma mansoni multidrug resistance protein 0.0028 0.0006 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0005 0.0125
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0089 0.0036 0.0036
Echinococcus granulosus BC026374 protein S09 family 0.0028 0.0006 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0006 0.0009
Leishmania major acetoin dehydrogenase e3 component-like protein 0.005 0.0017 0.0021
Echinococcus granulosus phd:f box containing protein 0.0045 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0012 0.0385
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0151 0.0065 0.0065
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0029 0.0006 0.0159
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0011 0.0353
Chlamydia trachomatis DNA topoisomerase I 0.0323 0.0149 1
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0063 0.0023 0.1413
Brugia malayi hypothetical protein 0.0094 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0178 0.0079 0.0079
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0027 0.0006 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0018 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0178 0.0079 0.0079
Schistosoma mansoni paired box protein pax-6 0.0019 0.0002 0.0001
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0151 0.0065 0.2151
Onchocerca volvulus Glucosylceramidase homolog 0.0195 0.0087 0.1795
Toxoplasma gondii thioredoxin reductase 0.0144 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0347 0.0161 0.016
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0077 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0014 0.0434
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) DIX domain-containing protein 0.0019 0.0002 0.0002
Echinococcus multilocularis ecdysone induced protein 78C 0.0178 0.0079 0.0079
Loa Loa (eye worm) MBCTL1 0.0057 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0075 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0027 0.0006 0.0159
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.6864 0.3316 0.4454
Onchocerca volvulus 0.003 0.0007 0.0131
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0012 0.0012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0118 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0178 0.0079 0.0079
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0005 0.01
Onchocerca volvulus 0.0027 0.0005 0.01
Plasmodium falciparum DNA repair protein REV1, putative 0.0024 0.0004 0.0002
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0029 0.0006 0.0008
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0027 0.0006 0.0006
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0011 0.0315
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0028 0.0006 0.0007
Loa Loa (eye worm) globin family protein 0.0028 0.0006 0.0006
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0005 0.0005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0019 0.0002 0.0002
Plasmodium vivax DNA repair protein REV1, putative 0.0024 0.0004 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.0178 0.0079 0.0079
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0276 0.0126 0.4174
Brugia malayi hypothetical protein 0.0022 0.0003 0.0003
Leishmania major p-glycoprotein e 0.0028 0.0006 0.0007
Trypanosoma brucei unspecified product 0.0053 0.0018 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0219
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0029 0.0006 0.0009
Echinococcus multilocularis cysteine protease 0.0019 0.0002 0.0002
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0096 0.0039 0.0039
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0008 0.0008
Onchocerca volvulus 0.0027 0.0005 0.01
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0004 0.0063
Echinococcus multilocularis rho GTPase activating protein 20 0.0284 0.013 0.013
Echinococcus multilocularis cysteine protease 0.0019 0.0002 0.0002
Schistosoma mansoni paired box protein pax-1-related 0.0019 0.0002 0.0001
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0029 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0005 0.0005
Echinococcus granulosus fmrfamide receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0011 0.0011
Brugia malayi Hemopexin family protein 0.003 0.0007 0.0007
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0014 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0002 0.0001
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0029 0.0006 0.0307
Trypanosoma cruzi DNA polymerase eta, putative 0.0132 0.0056 0.0075
Mycobacterium ulcerans flavoprotein disulfide reductase 0.005 0.0017 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Schistosoma mansoni DNA polymerase eta 0.0132 0.0056 0.0056
Echinococcus multilocularis kelch ECH associated protein 1 0.01 0.0041 0.0041
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0111 0.0046 0.0061
Plasmodium falciparum DNA gyrase subunit B 0.0063 0.0023 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0005 0.0005
Leishmania major short chain dehydrogenase-like protein 0.0029 0.0006 0.0008
Entamoeba histolytica multidrug resistance protein, putative 0.0028 0.0006 0.0137
Schistosoma mansoni chromobox protein 0.0067 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0002 0.0001
Onchocerca volvulus 0.0028 0.0006 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Echinococcus granulosus dna polymerase kappa 0.0106 0.0044 0.0044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0005 0.0005
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0029 0.0006 0.0006
Schistosoma mansoni flap endonuclease-1 0.0027 0.0005 0.0005
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0365 0.0169 0.5928
Loa Loa (eye worm) hypothetical protein 0.0165 0.0072 0.0072
Brugia malayi Cytochrome P450 family protein 0.0065 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0006 0.0171
Loa Loa (eye worm) RNA binding protein 0.0071 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Schistosoma mansoni caspase-7 (C14 family) 0.0186 0.0082 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Brugia malayi jmjC domain containing protein 0.0045 0.0014 0.0014
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0004 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0148 0.0064 0.0064
Brugia malayi Nuclear hormone receptor-like 1 0.0178 0.0079 0.0079
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0029 0.0006 0.0006
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0037 0.001 0.0332
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0002 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0259 0.0118 0.4092
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0604 0.0285 1
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0118 0.0049 0.0065
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0124 0.0053 0.1698
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0006 0.0159
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0311 0.0143 0.4934
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0029 0.0006 0.0193
Loa Loa (eye worm) globin family protein 0.0028 0.0006 0.0006
Echinococcus granulosus carboxylesterase 5A 0.0165 0.0072 0.0072
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0006 0.0009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Echinococcus granulosus multidrug resistance associated protein 1 0.0028 0.0006 0.0006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0089 0.0036 0.0036
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0118 0.0049 0.0065
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0007 0.0155
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0017 0.0021
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0124 0.0053 0.0069
Plasmodium vivax steroid dehydrogenase, putative 0.0029 0.0006 0.0005
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0001
Schistosoma mansoni Smad4 0.002 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0178 0.0079 0.0079
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0072 0.0027 0.0027
Echinococcus granulosus paired box protein pax 6 0.0019 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0009 0.0262
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0025 0.0024
Leishmania major DNA polymerase eta, putative 0.0132 0.0056 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0005 0.0005
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0027 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0094 0.0038 0.0038
Echinococcus multilocularis thyroid hormone receptor alpha 0.0178 0.0079 0.0079
Trypanosoma brucei membrane transporter protein, putative 0.0139 0.006 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0012 0.0385
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0025 0.0809
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0005 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Mycobacterium ulcerans carboxylesterase, LipT 0.0028 0.0006 0.0138
Giardia lamblia Reductase, putative 0.0029 0.0006 0.0151
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0003 0.0003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0016 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.1778 0.0853 0.0853
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0011 0.0011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.003 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Schistosoma mansoni thyroid hormone receptor 0.0178 0.0079 0.0078
Trichomonas vaginalis maltase-glucoamylase, putative 0.0019 0.0002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Mycobacterium ulcerans DNA polymerase IV 0.0106 0.0044 0.1484
Brugia malayi PHD-finger family protein 0.0019 0.0002 0.0002
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0074 0.0028 0.0028
Onchocerca volvulus 0.0019 0.0002 0.0028
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0124 0.0053 0.1724
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0005 0.0005
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0081 0.0032 0.103
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0118 0.0049 0.0065
Echinococcus multilocularis retinol dehydrogenase 11 0.0029 0.0006 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0178 0.0079 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.005 0.0017 0.0015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.0028 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0012 0.0012
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0005 0.0005
Brugia malayi Carboxylesterase family protein 0.0028 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0006 0.0126
Echinococcus granulosus steroid dehydrogenase 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0104 0.0043 0.1365
Onchocerca volvulus 0.0027 0.0005 0.01
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0003 0.0003
Echinococcus multilocularis caspase 8 0.0096 0.0039 0.0039
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0151 0.0065 0.0065
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Schistosoma mansoni nuclear receptor 0.0084 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0017 0.0022
Brugia malayi ORL1-like opioid receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis DNA polymerase eta, putative 0.0106 0.0044 0.1439
Onchocerca volvulus 0.0027 0.0005 0.01
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0005 0.0005
Echinococcus granulosus cathepsin l1 0.0019 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0263 0.012 0.012
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0111 0.0046 0.1505
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0003 0.0004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0112 0.0047 0.0061
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0005 0.0005
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.0075 0.0075
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0028 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0005 0.0005
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0031 0.0008 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Loa Loa (eye worm) jmjC domain-containing protein 0.0171 0.0075 0.0075
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0347 0.0161 0.0161
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0052 0.0018 0.056
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0084 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0028 0.0037
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0005 0.01
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0118 0.0049 0.0049
Brugia malayi Protein kinase domain containing protein 0.0018 0.0001 0.0001
Toxoplasma gondii aldehyde dehydrogenase 0.0263 0.012 0.0118
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0112 0.0047 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0178 0.0079 0.0079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0017 0.0995
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0008 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.1207 0.0577 0.0577
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0029 0.0006 0.0008
Leishmania major adenylate cyclase-like protein 0.0028 0.0006 0.0007
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0106 0.0044 0.0058
Echinococcus granulosus ATP binding cassette sub family G 0.0022 0.0003 0.0003
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0019 0.0002 0.0028
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0028 0.0006 0.0006
Schistosoma mansoni gliotactin 0.0028 0.0006 0.0005
Brugia malayi nuclear receptor NHR-88 0.0084 0.0033 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.006 0.0079
Echinococcus multilocularis zinc finger protein 0.0019 0.0002 0.0002
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0014 0.0014
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Trichomonas vaginalis alpha-glucosidase, putative 0.0052 0.0018 0.056
Trypanosoma brucei DNA polymerase eta, putative 0.0132 0.0056 0.0076
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0006 0.0009
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0124 0.0053 0.3446
Entamoeba histolytica short chain dehydrogenase family protein 0.0029 0.0006 0.0159
Onchocerca volvulus 0.0027 0.0005 0.01
Echinococcus granulosus survival motor neuron protein 1 0.1778 0.0853 0.0853
Leishmania major DNA topoisomerase 1A 0.0276 0.0126 0.0168
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0014 0.0018
Leishmania major cathepsin L-like protease 0.0074 0.0028 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0178 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0079 0.0031 0.003
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0029 0.0006 0.0159
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0012 0.0017
Brugia malayi chromobox protein homolog 3 0.0038 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Onchocerca volvulus 0.0028 0.0006 0.0113
Onchocerca volvulus Cell death protein 3 homolog 0.0186 0.0082 0.1701
Schistosoma mansoni tsg101-related 0.0061 0.0022 0.0022
Brugia malayi hypothetical protein 0.0028 0.0006 0.0006
Echinococcus multilocularis acetylcholinesterase 0.0165 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0178 0.0079 0.0079
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0027 0.0037
Plasmodium vivax SET domain protein, putative 0.0068 0.0025 0.0024
Mycobacterium tuberculosis Probable reductase 0.0328 0.0151 0.5302
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0017 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Onchocerca volvulus Protein cycle homolog 0.0037 0.001 0.0207
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0003 0.0076
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0004 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0007 0.0007
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0112 0.0047 0.0061
Brugia malayi Heterochromatin protein 1 0.0067 0.0025 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0012 0.0376
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Schistosoma mansoni hypothetical protein 0.0062 0.0022 0.0022
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0084 0.0033 0.0033
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus multilocularis lysine specific demethylase 5A 0.0168 0.0074 0.0074
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.0043 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis set domain proteins, putative 0.0533 0.0251 0.8327
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0002 0.0027
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0226 0.0102 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0005 0.0005
Plasmodium vivax importin-beta 2, putative 0.0032 0.0008 0.0006
Brugia malayi hypothetical protein 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Onchocerca volvulus 0.0019 0.0002 0.0027
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Leishmania major hypothetical protein, conserved 0.0045 0.0014 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0006 0.0005
Schistosoma mansoni paired box protein pax-6 0.0019 0.0002 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Brugia malayi Dopamine receptor 0.0027 0.0005 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Echinococcus granulosus hypothetical protein 0.0029 0.0006 0.0006
Onchocerca volvulus 0.0019 0.0002 0.0027
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Possible oxidoreductase 0.0029 0.0006 0.0193
Brugia malayi ImpB/MucB/SamB family protein 0.0132 0.0056 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0027 0.0006 0.0159
Schistosoma mansoni bromodomain containing protein 0.0019 0.0002 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0003 0.0003
Echinococcus granulosus ferritin 0.0037 0.001 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0042 0.1372
Echinococcus granulosus apoptotic protease activating factor 1 0.009 0.0036 0.0036
Toxoplasma gondii DNA topoisomerase I, putative 2.0665 1 1
Echinococcus multilocularis neuroligin 0.0028 0.0006 0.0006
Echinococcus granulosus sex peptide receptor 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0027 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.0011
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0106 0.0044 0.0058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0178 0.0079 0.0079
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0004 0.0004
Schistosoma mansoni inositol monophosphatase 0.0124 0.0053 0.0052
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0029 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0006 0.0159
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Entamoeba histolytica hypothetical protein 0.0347 0.0161 0.5313
Schistosoma mansoni thyroid hormone receptor 0.0178 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0132 0.0056 0.0056
Trypanosoma brucei p-glycoprotein 0.0028 0.0006 0.0008
Onchocerca volvulus 0.0027 0.0005 0.01
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0005 0.0005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0084 0.0033 0.0033
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0004 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0178 0.0079 0.0078
Echinococcus granulosus thyroid hormone receptor alpha 0.0084 0.0033 0.0033
Echinococcus granulosus ecdysone induced protein 78C 0.0178 0.0079 0.0079
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0012 0.0242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0029 0.0006 0.0126
Brugia malayi hypothetical protein 0.007 0.0026 0.0026
Chlamydia trachomatis DNA gyrase subunit B 0.0063 0.0023 0.0465
Echinococcus multilocularis steroid dehydrogenase 0.0029 0.0006 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.0138 0.0059 0.008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0178 0.0079 0.0079
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0003 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.012 0.4166
Trichomonas vaginalis guanylate cyclase, putative 0.0111 0.0046 0.1505
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0259 0.0118 0.0157
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0027 0.0006 0.0125
Schistosoma mansoni hypothetical protein 0.009 0.0036 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.017
Schistosoma mansoni alpha-glucosidase 0.0138 0.0059 0.0059
Trypanosoma cruzi ABC transporter, putative 0.0022 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0057 0.002 0.002
Brugia malayi hypothetical protein 0.0028 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0045
Brugia malayi AKH receptor 0.0027 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0309 0.0142 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0027 0.0006 0.0159
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0005 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Onchocerca volvulus 0.0027 0.0005 0.01
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0027 0.0006 0.0159
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0005 0.0005
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0005 0.0005
Brugia malayi RE15519p 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Mycobacterium ulcerans putative regulatory protein 0.0269 0.0123 0.4274
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0011 0.0213
Loa Loa (eye worm) DNA topoisomerase I 2.0665 1 1
Brugia malayi acetyltransferase, GNAT family protein 0.0641 0.0303 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0178 0.0079 0.0079
Echinococcus granulosus serotonin receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0004 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0027 0.0027
Onchocerca volvulus 0.0178 0.0079 0.162
Echinococcus multilocularis phd:f box containing protein 0.0045 0.0014 0.0014
Giardia lamblia NADH oxidase lateral transfer candidate 0.005 0.0017 0.0488
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0002 0.0002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0188 0.0084 0.0084
Plasmodium falciparum topoisomerase I 2.0665 1 1
Schistosoma mansoni jumonji domain containing protein 0.021 0.0094 0.0094
Schistosoma mansoni multidrug resistance protein 0.0139 0.006 0.0059
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0028 0.0006 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0002 0.0034
Brugia malayi nuclear hormone receptor family member odr-7 0.0084 0.0033 0.0033
Echinococcus multilocularis mothers against decapentaplegic 2 0.002 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0027 0.0006 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0033 0.0045
Schistosoma mansoni dishevelled 0.0019 0.0002 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0002 0.0001
Schistosoma mansoni myosin xvIII 0.0027 0.0005 0.0005
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0015 0.0015
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0005
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0144 0.0062 0.0062
Trypanosoma cruzi hypothetical protein 0.0021 0.0003 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Schistosoma mansoni nuclear receptor nhr-48 0.0084 0.0033 0.0033
Schistosoma mansoni caspase-7 (C14 family) 0.0255 0.0116 0.0115
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0111 0.0046 0.0061
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis geminin 0.1455 0.0697 0.0697
Treponema pallidum bacterioferrin (TpF1) 0.0037 0.001 0.0283
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0118 0.0049 0.0049
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0003 0.0003
Trypanosoma brucei metacaspase 0.0096 0.0039 0.0052
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0084 0.0033 0.0033
Echinococcus granulosus caspase 8 0.0096 0.0039 0.0039
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0007 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0017 0.0017
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0002 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.002 0.002
Onchocerca volvulus 0.0029 0.0006 0.0126
Trypanosoma brucei metacaspase MCA3 0.0096 0.0039 0.0052
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0255 0.0116 0.0116
Echinococcus granulosus kelch ECH associated protein 1 0.01 0.0041 0.0041
Leishmania major cytochrome p450-like protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) thioredoxin reductase 0.0144 0.0062 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0027 0.0006 0.0159
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0005 0.0005
Giardia lamblia Kinase, PLK 0.0206 0.0092 0.3021
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0029 0.0006 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0033 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0027 0.0006 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0001 0.0001
Echinococcus granulosus importin subunit beta 1 0.0032 0.0008 0.0008
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0037 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0043 0.0013 0.0013
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.6864 0.3316 0.4453
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0033 0.0033
Onchocerca volvulus 0.0086 0.0034 0.0695
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0029 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0006 0.0126
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0178 0.0079 0.0078
Onchocerca volvulus 0.0027 0.0005 0.01
Trichomonas vaginalis steroid dehydrogenase, putative 0.0029 0.0006 0.0189
Loa Loa (eye worm) multidrug resistance-associated protein 0.0022 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0027 0.0005 0.0005
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0008 0.0008
Leishmania major GTP-binding protein, putative 0.0024 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0004 0.0004
Echinococcus multilocularis musashi 0.0086 0.0034 0.0034
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0006 0.0159
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0006 0.0159
Brugia malayi serine/threonine-protein kinase plk-2 0.0206 0.0092 0.0092
Entamoeba histolytica hypothetical protein 0.0029 0.0006 0.0159
Leishmania major glycosyl hydrolase-like protein 0.0019 0.0002 0.0001
Schistosoma mansoni ran 0.0024 0.0004 0.0003
Echinococcus granulosus intermediate filament protein 0.0086 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.017
Toxoplasma gondii cytochrome p450 superfamily protein 0.0027 0.0006 0.0004
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.0006 0.0163
Plasmodium vivax glutathione reductase, putative 0.0144 0.0062 0.006
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0007 0.0006
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0002 0.0002
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0028 0.0006 0.0008
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Schistosoma mansoni retinoic acid receptor RXR 0.0178 0.0079 0.0078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0178 0.0079 0.162
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0029 0.0006 0.0057
Echinococcus multilocularis aryl hydrocarbon receptor 0.0148 0.0064 0.0064
Loa Loa (eye worm) MH1 domain-containing protein 0.0044 0.0014 0.0014
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0002 0.0002
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0004 0.0004
Trypanosoma brucei glycosyl hydrolase-like protein 0.0019 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0094 0.0038 0.0038
Brugia malayi nuclear hormone receptor 0.0178 0.0079 0.0079
Onchocerca volvulus 0.0028 0.0006 0.0113
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Echinococcus granulosus Pleckstrin G protein interacting region 0.0019 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0024 0.0024
Echinococcus granulosus muscleblind protein 0.0658 0.0311 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi RNA binding protein 0.0071 0.0027 0.0027
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Schistosoma mansoni single-minded 0.038 0.0176 0.0176
Trypanosoma brucei ABC transporter, putative 0.0022 0.0003 0.0004
Plasmodium vivax ataxin-2 like protein, putative 0.0138 0.0059 0.0058
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0178 0.0079 0.0078
Loa Loa (eye worm) DR-78 0.0084 0.0033 0.0033
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0005 0.0005
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0005 0.0005
Brugia malayi MH1 domain containing protein 0.0024 0.0004 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.001 0.001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0637 0.0301 1
Trypanosoma cruzi metacaspase 5, putative 0.0096 0.0039 0.0051
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.002 0.002
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Echinococcus granulosus DNA topoisomerase 1 2.0665 1 1
Brugia malayi Muscleblind-like protein 0.0658 0.0311 0.0311
Leishmania major hypothetical protein, conserved 0.0029 0.0006 0.0008
Echinococcus granulosus ATP binding cassette sub family G 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Leishmania major DNA polymerase kappa, putative 0.0024 0.0004 0.0004
Schistosoma mansoni smad 0.0044 0.0014 0.0013
Echinococcus granulosus acetylcholinesterase 0.0165 0.0072 0.0072
Echinococcus granulosus retinol dehydrogenase 11 0.0029 0.0006 0.0006
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0029 0.0006 0.0006
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0063 0.0023 0.0694
Echinococcus multilocularis steroid dehydrogenase 0.0029 0.0006 0.0006
Trypanosoma brucei multidrug resistance protein E 0.0028 0.0006 0.0008
Brugia malayi polk-prov protein 0.0053 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.1455 0.0697 0.0697
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0226 0.0102 0.0101
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0124 0.0053 0.0071
Echinococcus multilocularis expressed conserved protein 0.0097 0.0039 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0017 0.0556
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.003 0.0007 0.0005
Loa Loa (eye worm) nuclear factor I 0.0024 0.0004 0.0004
Onchocerca volvulus 0.003 0.0007 0.0135
Echinococcus multilocularis apoptotic protease activating factor 1 0.009 0.0036 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.0025 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0074 0.0028 0.0028
Toxoplasma gondii oxidoreductase, putative 0.0029 0.0006 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0044 0.0014 0.0014
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0029 0.0006 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0178 0.0079 0.0079
Echinococcus granulosus paired box protein pax 6 0.0019 0.0002 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0018 0.0001 0.001
Leishmania major short chain dehydrogenase, putative 0.0029 0.0006 0.0008
Schistosoma mansoni tsg101-related 0.0061 0.0022 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0001 0.0003
Brugia malayi neuropeptide F receptor 0.0027 0.0005 0.0005
Echinococcus granulosus chromobox protein 1 0.0067 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0193 0.0086 0.0086
Brugia malayi nuclear receptor NHR-67 0.0084 0.0033 0.0033
Echinococcus multilocularis para nitrobenzyl esterase 0.0028 0.0006 0.0006
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0298 0.0137 0.0137
Brugia malayi jmjC domain containing protein 0.0045 0.0014 0.0014
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0111 0.0046 0.0061
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.0006 0.0161
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Leishmania major short chain dehydrogenase/reductase, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0006 0.0005
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0004 0.0002
Brugia malayi Carboxylesterase family protein 0.0165 0.0072 0.0072
Schistosoma mansoni cpg binding protein 0.0065 0.0024 0.0024
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0006 0.0006
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.002 0.002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0005 0.0005
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.0075 0.0075
Brugia malayi PHD-finger family protein 0.003 0.0007 0.0007
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0017 0.0016
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0063 0.0023 0.0462
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0178 0.0079 0.0079
Entamoeba histolytica ABC transporter, putative 0.0022 0.0003 0.0036
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0002 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0188 0.0084 0.0082
Loa Loa (eye worm) fibroinase 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Plasmodium falciparum glutathione reductase 0.0144 0.0062 0.006
Giardia lamblia GTOR 0.0052 0.0017 0.0519
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.001
Echinococcus multilocularis ATP binding cassette sub family G 0.0022 0.0003 0.0003
Giardia lamblia Fructose-bisphosphate aldolase 0.0637 0.0301 1
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0007 0.0006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0006 0.0006
Trichomonas vaginalis mercuric reductase, putative 0.005 0.0017 0.0525
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0003 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0017 0.0022
Schistosoma mansoni globin X 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0347 0.0161 0.016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0017 0.0017
Schistosoma mansoni opsin-like receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0014
Echinococcus granulosus dna polymerase eta 0.0132 0.0056 0.0056
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Brugia malayi orphan nuclear receptor NR2E1 0.0084 0.0033 0.0033
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0006 0.0005
Trypanosoma brucei DNA topoisomerase IB, large subunit 1.5391 0.7446 1
Entamoeba histolytica hypothetical protein 0.0028 0.0006 0.0137
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0008 0.0006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0002 0.0003
Echinococcus granulosus caspase 0.0255 0.0116 0.0116
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0012 0.0376
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Possible oxidoreductase 0.0029 0.0006 0.0193
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0658 0.0311 0.0311
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.009 0.009
Plasmodium vivax DNA topoisomerase II, putative 0.0063 0.0023 0.0021
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0658 0.0311 0.0311
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0045 0.0014 0.0014
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.002 0.002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0178 0.0079 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.0263 0.012 0.0119
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0259 0.0118 0.4092
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Loa Loa (eye worm) hypothetical protein 0.0405 0.0188 0.0188
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.0075 0.0075
Mycobacterium ulcerans hydrolase 0.0026 0.0005 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.0178 0.0079 0.0079
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0323 0.0149 1
Leishmania major DNA damage repair protein, putative 0.0024 0.0004 0.0004
Echinococcus multilocularis snurportin 1 0.0344 0.0159 0.0159
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0365 0.0169 0.5871
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0178 0.0079 0.162
Echinococcus multilocularis chromobox protein 1 0.0067 0.0025 0.0025
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0001 0.0001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0052 0.0018 0.056
Trichomonas vaginalis alpha-glucosidase, putative 0.0052 0.0018 0.056
Toxoplasma gondii DNA topoisomerase family protein 0.0276 0.0126 0.0124
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0005 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0019 0.0002 0.0002
Brugia malayi hypothetical protein 0.1274 0.0609 0.0609
Echinococcus granulosus lamin dm0 0.0086 0.0034 0.0034
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0011 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Echinococcus multilocularis protein dispatched 1 0.0051 0.0017 0.0017
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0063 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0226 0.0102 0.0102
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0029 0.0006 0.0159
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0017 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0027 0.0006 0.0159
Onchocerca volvulus 0.0027 0.0005 0.01
Brugia malayi sulfakinin receptor protein 0.0027 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0027 0.0005 0.0005
Brugia malayi isocitrate dehydrogenase 0.0118 0.0049 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0033 0.0033
Echinococcus multilocularis lamin dm0 0.0086 0.0034 0.0034
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0028 0.0006 0.0004
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0181 0.008 0.2613
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0096 0.0039 0.0039
Echinococcus multilocularis inositol monophosphatase 1 0.0124 0.0053 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0138 0.0059 0.0079
Loa Loa (eye worm) hypothetical protein 0.0094 0.0038 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0011 0.0015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Toxoplasma gondii melibiase subfamily protein 0.0226 0.0102 0.01
Schistosoma mansoni alpha glucosidase 0.0052 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0002 0.0031
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0011 0.0011
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0263 0.012 0.012
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0006 0.0006
Brugia malayi ecdysteroid receptor 0.0178 0.0079 0.0079
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0029 0.0006 0.0005
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0007 0.0008
Entamoeba histolytica short chain dehydrogenase family protein 0.0029 0.0006 0.0159
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0006 0.0159
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0006 0.0159
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0027 0.0027
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0027 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Echinococcus multilocularis kelch ECH associated protein 1 0.01 0.0041 0.0041
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Onchocerca volvulus 0.0071 0.0027 0.0549
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.006 0.0079
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0006 0.0006
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0111 0.0046 0.2223
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0052 0.0018 0.0531
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0178 0.0079 0.0078
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0005 0.0136
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.005 0.0017 0.0017
Brugia malayi Niemann-Pick C1 protein precursor 0.0104 0.0043 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0002 0.0033
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0007 0.0193
Brugia malayi bZIP transcription factor family protein 0.0089 0.0036 0.0036
Echinococcus granulosus mothers against decapentaplegic 5 0.0044 0.0014 0.0014
Brugia malayi Dehydrogenases, short chain protein 2 0.0029 0.0006 0.0006
Echinococcus granulosus retinol dehydrogenase 11 0.0029 0.0006 0.0006
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0188 0.0084 0.0082
Plasmodium vivax DNA gyrase subunit B, putative 0.0063 0.0023 0.0021
Giardia lamblia ABC transporter 0.0021 0.0003 0.002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.001 0.001
Schistosoma mansoni BC026374 protein (S09 family) 0.0028 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0052 0.0018 0.0018
Brugia malayi Retinol dehydrogenase 12 0.0029 0.0006 0.0006
Echinococcus multilocularis multidrug resistance associated protein 1 0.0028 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0018 0.0024
Treponema pallidum NADH oxidase 0.005 0.0017 0.0488
Onchocerca volvulus Alhambra homolog 0.003 0.0007 0.0138
Treponema pallidum fructose-bisphosphate aldolase 0.0637 0.0301 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0045
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0132 0.0056 0.1951
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0022 0.0029
Schistosoma mansoni alpha-glucosidase 0.0138 0.0059 0.0059
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.005 0.0017 0.0015
Schistosoma mansoni apoferritin-2 0.0037 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Trypanosoma brucei DNA topoisomerase IA, putative 0.0276 0.0126 0.0169
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0004 0.0004
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0144 0.0062 0.0062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0033 0.0033
Giardia lamblia DNA damage repair protein 0.0024 0.0004 0.0069
Loa Loa (eye worm) transcription factor SMAD2 0.0647 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0017 0.0017
Echinococcus granulosus Niemann Pick C1 protein 0.0104 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Brugia malayi MH1 domain containing protein 0.0044 0.0014 0.0014
Trichomonas vaginalis ferritin, putative 0.0037 0.001 0.0321
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0029 0.0006 0.0057
Schistosoma mansoni DNA topoisomerase type I 2.0665 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Entamoeba histolytica deoxycytidyl transferase, putative 0.0077 0.003 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0004 0.0003
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0027 0.0005 0.01
Echinococcus multilocularis multidrug resistance associated protein 7 0.0028 0.0006 0.0006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3575 0.1724 0.1724
Leishmania major cytochrome p450-like protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0017 0.0017
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Schistosoma mansoni lamin 0.0086 0.0034 0.0034
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0188 0.0084 0.2762
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Schistosoma mansoni protein phosphatase 2C 0.0045 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0029 0.0006 0.0008
Loa Loa (eye worm) acetylcholinesterase 1 0.0165 0.0072 0.0072
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0016 0.0016
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0019 0.0002 0.0023
Brugia malayi PXA domain containing protein 0.0022 0.0003 0.0003
Brugia malayi ecdysone receptor 0.0084 0.0033 0.0033
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.005 0.0017 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0178 0.0079 0.0079
Onchocerca volvulus Mothers against decapentaplegic homolog 0.002 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0104 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis spcc417.12 protein, putative 0.0028 0.0006 0.0169
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Echinococcus multilocularis lysine specific demethylase 6a 0.0045 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0383 0.0178 0.0178
Brugia malayi Gooseberry protein 0.0019 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0044 0.0014 0.0014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0033 0.0676
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0027 0.0006 0.0159
Entamoeba histolytica DNA topoisomerase III, putative 0.0144 0.0062 0.2016
Brugia malayi DIX domain containing protein 0.0019 0.0002 0.0002
Trichomonas vaginalis ran, putative 0.0024 0.0004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0165 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0019 0.0002 0.0002
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0024 0.0004 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0111 0.0046 0.1593
Leishmania major dehydrogenase-like protein 0.0029 0.0006 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0025 0.0809
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0027 0.0006 0.0159
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0008 0.0011
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0178 0.0079 0.0079
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0226 0.0102 0.0101
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0276 0.0126 0.0168
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0188 0.0084 0.2762
Trypanosoma cruzi DNA polymerase kappa, putative 0.0106 0.0044 0.0058
Mycobacterium tuberculosis Probable dehydrogenase 0.0029 0.0006 0.0193
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0028 0.0006 0.0007
Brugia malayi PAS domain containing protein 0.038 0.0176 0.0176
Schistosoma mansoni dishevelled 0.0019 0.0002 0.0001
Echinococcus multilocularis caspase 3 0.0158 0.0069 0.0069
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0118 0.0049 0.0049
Brugia malayi Cytochrome P450 family protein 0.0065 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Brugia malayi dehydrogenases, short chain protein 2 0.0029 0.0006 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0019 0.0002 0.0033
Leishmania major 3-keto-dihydrosphingosine reductase 0.0029 0.0006 0.0008
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0063 0.0023 0.0029
Trichomonas vaginalis DNA topoisomerase II, putative 0.0063 0.0023 0.073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0065 0.0024 0.0024
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0139 0.006 0.006
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0077 0.003 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0042 0.1372
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Mycobacterium ulcerans carveol-like dehydrogenase 0.0029 0.0006 0.0159
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0033 0.0033
Trypanosoma cruzi DNA topoisomerase III, putative 0.0144 0.0062 0.0082
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.0006 0.013
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0007 0.0007
Echinococcus multilocularis carboxylesterase 5A 0.0165 0.0072 0.0072
Brugia malayi hypothetical protein 0.0084 0.0033 0.0033
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0005 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0001 0.0019
Echinococcus multilocularis dna polymerase eta 0.0132 0.0056 0.0056
Brugia malayi Serotonin receptor 0.0027 0.0005 0.0005
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0037 0.001 0.0198
Brugia malayi Isocitrate dehydrogenase 0.0118 0.0049 0.0049
Echinococcus granulosus thioredoxin glutathione reductase 0.0145 0.0062 0.0062
Giardia lamblia ABC transporter, putative 0.0028 0.0006 0.0129
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0029 0.0006 0.0193
Loa Loa (eye worm) matrixin family protein 0.0051 0.0017 0.0017
Mycobacterium leprae Possible regulatory protein 0.0111 0.0046 0.1466
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0003 0.003
Onchocerca volvulus 0.0029 0.0006 0.0126
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0017 0.0017
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0004 0.0002
Loa Loa (eye worm) acetyltransferase 0.0641 0.0303 0.0303
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0029 0.0006 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0002 0.0002
Trypanosoma brucei chrX additional, unordered contigs 0.0024 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0005 0.0005
Treponema pallidum DNA topoisomerase I (topA) 0.0323 0.0149 0.491
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0079 0.0031 0.004
Brugia malayi dehydrogenases, short chain protein 9 0.0029 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0027 0.0006 0.0125
Schistosoma mansoni Smad4 0.002 0.0002 0.0002
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0118 0.0049 0.1702
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.002 0.002
Onchocerca volvulus 0.0027 0.0005 0.01
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0124 0.0053 0.0051
Onchocerca volvulus 0.0027 0.0005 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0052 0.0018 0.056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.005 0.0017 0.0516
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0012 0.0012
Brugia malayi Dopamine receptor protein 1 0.0027 0.0005 0.0005
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0044 0.0014 0.0013
Echinococcus multilocularis ATP binding cassette sub family G 0.0022 0.0003 0.0003
Plasmodium falciparum glutathione reductase 0.005 0.0017 0.0015
Plasmodium vivax topoisomerase I, putative 2.0665 1 1
Echinococcus granulosus cytochrome P450 2K1 0.0027 0.0006 0.0006
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0017 0.0022
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0005 0.0005
Trypanosoma cruzi metacaspase, putative 0.0096 0.0039 0.0051
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0027 0.0006 0.0125
Leishmania major hypothetical protein, conserved 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0057 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0178 0.0079 0.0079
Onchocerca volvulus Huntingtin homolog 0.0405 0.0188 0.3899
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0029 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Onchocerca volvulus 0.0029 0.0006 0.0126
Brugia malayi Pre-SET motif family protein 0.0068 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0219
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0044 0.0014 0.0014
Echinococcus multilocularis BC026374 protein (S09 family) 0.0028 0.0006 0.0006
Onchocerca volvulus 0.0028 0.0006 0.0113
Brugia malayi conserved hypotetical protein 0.0084 0.0033 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0005 0.0005
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0029 0.0006 0.0008
Echinococcus granulosus chromobox protein 1 0.0067 0.0025 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0006 0.0159
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0005 0.0005
Echinococcus granulosus caspase 2 0.0186 0.0082 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0237 0.0107 0.0144
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0027 0.0006 0.0125
Echinococcus granulosus paired box protein pax 1 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.1207 0.0577 0.0577
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0063 0.0023 0.0764
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0124 0.0053 0.0069
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0188 0.0084 0.0082
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0027 0.0006 0.0159
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0006 0.0006
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0344 0.0159 0.0159
Brugia malayi Globin family protein 0.0028 0.0006 0.0006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0094 0.0038 0.0038
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0144 0.0062 0.2154
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0144 0.0062 0.0062
Onchocerca volvulus Serine\/threonine kinase homolog 0.0206 0.0092 0.1904
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0178 0.0079 0.0079
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0259 0.0118 0.0117
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.0171
Brugia malayi Cytochrome P450 family protein 0.0049 0.0016 0.0016
Echinococcus granulosus tumor protein p63 0.0389 0.0181 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0005
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0029 0.0006 0.0193
Trypanosoma brucei DNA topoisomerase ii 0.0063 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.005 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0178 0.0079 0.0079
Schistosoma mansoni cpg binding protein 0.0065 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0092 0.0092
Onchocerca volvulus 0.0027 0.0005 0.01
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.0092 0.3042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Brugia malayi hypothetical protein 0.0347 0.0161 0.0161
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Echinococcus granulosus flap endonuclease 1 0.0029 0.0007 0.0007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.005 0.0017 0.0021
Leishmania major hypothetical protein, conserved 0.0138 0.0059 0.0079
Mycobacterium tuberculosis Probable oxidoreductase 0.0365 0.0169 0.5928
Echinococcus granulosus inositol monophosphatase 1 0.0124 0.0053 0.0053
Onchocerca volvulus 0.0027 0.0005 0.01
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0037 0.001 0.001
Echinococcus multilocularis DNA topoisomerase 1 2.0665 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0124 0.0053 0.0069
Brugia malayi Smad1 0.0044 0.0014 0.0014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0019 0.0002 0.0033
Schistosoma mansoni ABC transporter 0.0018 0.0001 0.0001
Brugia malayi G-protein coupled receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0032 0.0008 0.0007
Trypanosoma brucei cytochrome P450, putative 0.0065 0.0024 0.0032
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0276 0.0126 0.4327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.028
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0263 0.012 0.016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0111 0.0046 0.1476
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0363 0.0168 0.0168
Schistosoma mansoni bromodomain containing protein 0.0019 0.0002 0.0001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0005 0.0005
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0226 0.0102 0.0102
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0003 0.0003
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0029 0.0006 0.0009
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Brugia malayi N-terminal motif family protein 0.0383 0.0178 0.0178
Mycobacterium tuberculosis Carboxylesterase LipT 0.0028 0.0006 0.0171
Trypanosoma brucei metacaspase MCA2 0.0096 0.0039 0.0052
Schistosoma mansoni biogenic amine receptor 0.0027 0.0005 0.0005
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0045 0.0014 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0027 0.0006 0.0159
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0005 0.0005
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0013 0.0013
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.005 0.0017 0.0015
Leishmania major pentamidine resistance protein 1 0.0028 0.0006 0.0007
Onchocerca volvulus Globin homolog 0.0028 0.0006 0.0117
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0311 0.0143 0.5004
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0002 0.0002
Mycobacterium ulcerans bacterioferritin BfrA 0.0037 0.001 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0008 0.0008
Schistosoma mansoni inositol monophosphatase 0.0124 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.004 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0018 0.0023
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0004 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0144 0.0062 0.0082
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0029 0.0006 0.0008
Schistosoma mansoni ferritin 0.0037 0.001 0.001
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0006 0.0171
Onchocerca volvulus 0.0029 0.0006 0.0126
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0006 0.0159
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Schistosoma mansoni hypothetical protein 0.0033 0.0008 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0096 0.0039 0.0039
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0178 0.0079 0.0078
Trypanosoma cruzi metacaspase, putative 0.0096 0.0039 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0005 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0178 0.0079 0.0079
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0029 0.0006 0.0008
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0027 0.0855
Brugia malayi hypothetical protein 0.0028 0.0006 0.0006
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0079 0.0031 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0007 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0037 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0017 0.0017
Brugia malayi paired box protein 0.0019 0.0002 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0011 0.0014
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0298 0.0137 0.0137
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0017 0.0017
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0037 0.001 0.001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0118 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0063 0.0023 0.0462
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi hypoxia-induced factor 1 0.1126 0.0538 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0005 0.0005
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.023 0.0104 0.0104
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0085 0.0033 0.0044
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.023 0.0104 0.0104
Entamoeba histolytica hypothetical protein 0.0347 0.0161 0.5313
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0004 0.0005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.0039 0.0038
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0641 0.0303 0.0303
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0011 0.0011
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0004 0.0005
Leishmania major DNA topoisomerase III, putative 0.033 0.0152 0.0204
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0017 0.0017
Brugia malayi MH2 domain containing protein 0.0647 0.0306 0.0306
Schistosoma mansoni ankyrin 23/unc44 0.0017 0 0.0000000018242
Schistosoma mansoni cpg binding protein 0.0062 0.0022 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0005 0.0005
Brugia malayi MH2 domain containing protein 0.002 0.0002 0.0002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0006 0.0005
Brugia malayi nuclear receptor RXR 0.0094 0.0038 0.0038
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Onchocerca volvulus 0.009 0.0036 0.0734
Schistosoma mansoni smad1 5 8 and 0.0044 0.0014 0.0013
Echinococcus granulosus single minded 2 0.0269 0.0123 0.0123
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.003 0.003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.003 0.1017
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0005 0.0005
Brugia malayi CXXC zinc finger family protein 0.0062 0.0022 0.0022
Plasmodium falciparum metacaspase 1 0.0096 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0084 0.0033 0.0033
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0002 0.0027
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0029 0.0006 0.0006
Trypanosoma brucei DNA topoisomerase III, putative 0.0284 0.013 0.0174
Giardia lamblia PHD finger protein 15 0.003 0.0007 0.017
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0034 0.0034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis oxidoreductase 0.0029 0.0006 0.0006
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0057
Entamoeba histolytica hypothetical protein 0.0026 0.0005 0.011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) matrixin family protein 0.0047 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0084 0.0033 0.0033
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0004 0.0002
Leishmania major ABC-thiol transporter 0.0028 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0053 0.0018 0.0018
Brugia malayi ABC transporter family protein 0.0018 0.0001 0.0001
Brugia malayi Carboxylesterase family protein 0.0028 0.0006 0.0006
Echinococcus granulosus dnaJ subfamily B 0.0883 0.042 0.042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0033 0.0033
Entamoeba histolytica acetyltransferase, GNAT family 0.0173 0.0076 0.2485
Schistosoma mansoni hypothetical protein 0.1455 0.0697 0.0697
Trypanosoma brucei DNA polymerase IV, putative 0.0106 0.0044 0.0059
Plasmodium vivax thioredoxin reductase, putative 0.0144 0.0062 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0178 0.0079 0.0079
Mycobacterium ulcerans oxidoreductase 0.0029 0.0006 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0027 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0007 0.0009
Schistosoma mansoni neuroligin 3 (S09 family) 0.0028 0.0006 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0011 0.033
Brugia malayi MH2 domain containing protein 0.0044 0.0014 0.0014
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0027 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0044 0.0014 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0005 0.0005
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0017 0.0017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Brugia malayi ABC transporter transmembrane region family protein 0.0028 0.0006 0.0006
Brugia malayi cytochrome P450 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0637 0.0301 1
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0063 0.0023 0.0023
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0028 0.0006 0.0006
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0005 0.0005
Giardia lamblia DINP protein human, muc B family 0.0085 0.0033 0.1051
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0004 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.0178 0.0079 0.162
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0028 0.0006 0.0006
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0005 0.0005
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Brugia malayi Thioredoxin reductase 0.0144 0.0062 0.0062
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0029 0.0006 0.0159
Echinococcus granulosus Niemann Pick C1 protein 0.0148 0.0064 0.0064
Brugia malayi hypothetical protein 0.009 0.0036 0.0036
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0181 0.008 0.2613
Schistosoma mansoni chromobox protein 0.0067 0.0025 0.0025
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0027 0.0006 0.0125
Plasmodium falciparum ABC transporter G family member 2 0.0022 0.0003 0.0001
Giardia lamblia DNA topoisomerase III 0.0276 0.0126 0.4152
Echinococcus granulosus lysine specific demethylase 5A 0.0171 0.0075 0.0075
Plasmodium falciparum DNA topoisomerase 3, putative 0.0276 0.0126 0.0124
Schistosoma mansoni ferritin light chain 0.0037 0.001 0.001
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0013 0.0013
Onchocerca volvulus 0.0363 0.0168 0.3476
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0045 0.0014 0.0013
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0005 0.0005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0084 0.0033 0.0033
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0017 0.0016
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0012 0.0385
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Onchocerca volvulus 0.0029 0.0006 0.0126
Brugia malayi Matrixin family protein 0.0051 0.0017 0.0017
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0004 0.0004
Plasmodium falciparum thioredoxin reductase 0.0144 0.0062 0.006
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0045
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0002 0.0008
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0178 0.0079 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypoxia-induced factor 1 0.1126 0.0538 0.0538
Echinococcus granulosus snurportin 1 0.0344 0.0159 0.0159
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.019 0.0085 0.0083
Brugia malayi jmjC domain containing protein 0.0045 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.1274 0.0609 0.0609
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0027 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0017 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0033 0.0033
Schistosoma mansoni RAR-like nuclear receptor 0.0178 0.0079 0.0078
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0029 0.0006 0.0193
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Echinococcus multilocularis protein patched 0.0044 0.0014 0.0014
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0027 0.0005 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0004 0.0005
Onchocerca volvulus Retinal homeobox protein Rx homolog 0.0019 0.0002 0.0028
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0018 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Mycobacterium leprae putative cytochrome p450 0.0027 0.0006 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Schistosoma mansoni smad1 5 8 and 0.0044 0.0014 0.0013
Loa Loa (eye worm) dehydrogenase 0.0029 0.0006 0.0006
Schistosoma mansoni histamine h1 receptor 0.0027 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0226 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0094 0.0038 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0017 0.0017
Leishmania major hypothetical protein, conserved 0.0139 0.006 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0011 0.0353
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.009 0.009
Plasmodium falciparum thioredoxin reductase 0.005 0.0017 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0012 0.0385
Brugia malayi G protein-coupled receptor 0.0027 0.0005 0.0005
Echinococcus granulosus Smad4 0.0044 0.0014 0.0014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0005 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0022 0.0029
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0111 0.0046 0.1505
Mycobacterium ulcerans hypothetical protein 0.0027 0.0006 0.013
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0118 0.0049 0.0066
Echinococcus multilocularis 0.0027 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0006 0.0126
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1778 0.0853 0.0853
Onchocerca volvulus 0.0028 0.0006 0.0117
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0003
Trypanosoma brucei membrane transporter protein, putative 0.0139 0.006 0.008
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0086 0.0034 0.0034
Brugia malayi hypothetical protein 0.0074 0.0028 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0096 0.0039 0.0037
Brugia malayi multidrug resistance related protein 1 0.0028 0.0006 0.0006
Leishmania major cytochrome p450-like protein 0.0065 0.0024 0.0031
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0178 0.0079 0.0079
Schistosoma mansoni carbonyl reductase 0.0029 0.0006 0.0006
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0001
Loa Loa (eye worm) TOPoisomerase family member 0.0063 0.0023 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.002 0.002
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.002 0.0002 0.0002
Schistosoma mansoni ferritin 0.0037 0.001 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0027 0.0036
Loa Loa (eye worm) hypothetical protein 0.0186 0.0082 0.0082
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0005 0.0005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0033 0.0676
Leishmania major DNA topoisomerase IB, large subunit 1.5391 0.7446 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0138 0.0059 0.0058
Echinococcus granulosus caspase 3 0.0158 0.0069 0.0069
Onchocerca volvulus 0.0029 0.0006 0.0126
Schistosoma mansoni biogenic amine receptor 0.0027 0.0005 0.0005
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0017 0.0023
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0017 0.0017
Schistosoma mansoni terminal deoxycytidyl transferase 0.0077 0.003 0.0029
Brugia malayi Cytochrome P450 family protein 0.0027 0.0006 0.0006
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0641 0.0303 0.0302
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0028 0.0037
Echinococcus granulosus WW domain containing oxidoreductase 0.0029 0.0006 0.0006
Loa Loa (eye worm) paired box protein 0.0019 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0065 0.0024 0.0777
Schistosoma mansoni intermediate filament proteins 0.0086 0.0034 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0276 0.0126 0.0168
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.0028 0.0006 0.0006
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni microtubule-associated protein tau 0.1503 0.072 0.072
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis Kelch repeat type 1 0.01 0.0041 0.0041
Loa Loa (eye worm) glutathione reductase 0.0144 0.0062 0.0062
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0027 0.0006 0.0125
Trichomonas vaginalis adenylate cyclase, putative 0.0111 0.0046 0.1505
Schistosoma mansoni jumonji domain containing protein 0.0045 0.0014 0.0014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) pax transcription factor protein 2 0.1012 0.0483 0.0483
Trypanosoma brucei trypanothione reductase 0.0144 0.0062 0.0083
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0005 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0027 0.0006 0.013
Loa Loa (eye worm) hypothetical protein 0.0181 0.008 0.008
Trichomonas vaginalis guanylate cyclase, putative 0.0111 0.0046 0.1505
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0005 0.0005
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0005
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0029 0.0006 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0259 0.0118 0.4112
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0063 0.0023 0.0023
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0027 0.0005 0.01
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0178 0.0079 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0118 0.0049 0.0048
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0084 0.0033 0.0033
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0006 0.013
Onchocerca volvulus 0.0144 0.0062 0.1277
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0003 0.0003
Brugia malayi CHE-14 protein 0.0044 0.0014 0.0014
Onchocerca volvulus 0.0086 0.0034 0.0695
Schistosoma mansoni apoferritin-2 0.0037 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0004 0.0004
Schistosoma mansoni retinal dehydrogenase 0.0029 0.0006 0.0006
Brugia malayi RNA, U transporter 1 0.0092 0.0037 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0003 0.0003
Schistosoma mansoni lamin 0.0086 0.0034 0.0034
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0028 0.0006 0.0007
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0028 0.0037
Schistosoma mansoni phd/f-box containing protein 0.0045 0.0014 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.012 0.4166
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0003 0.0003
Echinococcus multilocularis conserved hypothetical protein 0.0795 0.0377 0.0377
Schistosoma mansoni opsin-like receptor 0.0027 0.0005 0.0005
Brugia malayi bHLH-PAS transcription factor 0.0269 0.0123 0.0123
Schistosoma mansoni DNA topoisomerase II 0.0063 0.0023 0.0022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0033 0.0033
Entamoeba histolytica hypothetical protein 0.0347 0.0161 0.5313
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0044 0.0014 0.0014
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0029 0.0006 0.0126
Loa Loa (eye worm) hypothetical protein 0.0054 0.0019 0.0019
Trypanosoma cruzi polo-like protein kinase, putative 0.0206 0.0092 0.0123
Trypanosoma cruzi short chain dehydrogenase, putative 0.0029 0.0006 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0124 0.0053 0.1724
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0027 0.0006 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.0039 0.0038
Schistosoma mansoni ran 0.0024 0.0004 0.0003
Brugia malayi vab-3 gene. 0.0019 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0193 0.0086 0.0086
Toxoplasma gondii DNA topoisomerase 2, putative 0.0063 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.017
Trypanosoma brucei unspecified product 0.0053 0.0018 0.0025
Trypanosoma cruzi membrane transporter protein, putative 0.0139 0.006 0.0079
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0033 0.0033
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0005 0.0005
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0033 0.0033
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.005 0.0017 0.0516
Brugia malayi mothers against decapentaplegic homolog 3 0.002 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.017 0.0075 0.0074
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.0039 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0012 0.0012
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0002 0.0033
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0039
Echinococcus multilocularis dnaJ subfamily B 0.0883 0.042 0.042
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0012 0.0012
Schistosoma mansoni jun-related protein 0.0072 0.0027 0.0027
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0206 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.0171
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Trypanosoma brucei Metacaspase-4 0.0096 0.0039 0.0052
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0017 0.0016
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0043 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi mbt repeat family protein 0.005 0.0017 0.0017
Echinococcus granulosus para nitrobenzyl esterase 0.0028 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0027 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Schistosoma mansoni dep domain containing protein 0.0019 0.0002 0.0001
Plasmodium falciparum DNA topoisomerase 2 0.0063 0.0023 0.0021
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0005 0.0005
Echinococcus multilocularis nuclear receptor nhr 48 0.0084 0.0033 0.0033
Mycobacterium tuberculosis Probable dehydrogenase 0.0328 0.0151 0.5302
Loa Loa (eye worm) hypothetical protein 0.0104 0.0043 0.0043
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0048 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0027 0.0006 0.0125
Brugia malayi hypothetical protein 0.0138 0.0059 0.0059
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0604 0.0285 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0017 0.0337
Echinococcus multilocularis acetylcholinesterase 0.0165 0.0072 0.0072
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Entamoeba histolytica Ran family GTPase 0.0024 0.0004 0.0071
Giardia lamblia MRP-like ABC transporter 0.0028 0.0006 0.0129
Schistosoma mansoni kinase 0.0105 0.0043 0.0043
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0005 0.0005
Echinococcus granulosus tar DNA binding protein 0.0071 0.0027 0.0027
Trypanosoma cruzi metacaspase, putative 0.0096 0.0039 0.0051
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Schistosoma mansoni zinc finger protein 0.0019 0.0002 0.0001
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.006 0.0079
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0027 0.0006 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0214
Onchocerca volvulus 0.0019 0.0002 0.0027
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Mycobacterium ulcerans DNA gyrase subunit B 0.0063 0.0023 0.0733
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0012 0.0012
Echinococcus granulosus ATP binding cassette sub family G 0.0022 0.0003 0.0003
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0405 0.0188 0.0188
Brugia malayi mbt repeat family protein 0.005 0.0017 0.0017
Echinococcus multilocularis thioredoxin glutathione reductase 0.0145 0.0062 0.0062
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0027 0.0006 0.0125
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0028 0.0006 0.0006
Mycobacterium leprae Probable oxidoreductase 0.0029 0.0006 0.0057
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0311 0.0143 0.4987
Brugia malayi hypothetical protein 0.0405 0.0188 0.0188
Brugia malayi Serotonin receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0259 0.0118 0.0118
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0094 0.0038 0.0038
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0029 0.0006 0.0126
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.005 0.0017 0.0548
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0017 0.0017
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0003 0.003
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0003 0.0003
Brugia malayi intermediate filament protein 0.0086 0.0034 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0006 0.0006
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0005 0.01
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0383 0.0178 0.3677
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0027 0.0036
Schistosoma mansoni neuropeptide receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis sucrase-isomaltase, putative 0.0052 0.0018 0.056
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Trypanosoma brucei polo-like protein kinase 0.0206 0.0092 0.0124
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0029 0.0006 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.0171
Echinococcus granulosus orexin receptor type 2 0.0027 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.023 0.0104 0.0104
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0027 0.0006 0.0159
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0052 0.0018 0.056
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0029 0.0006 0.0006
Trypanosoma cruzi cytochrome P450, putative 0.0065 0.0024 0.0031
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Leishmania major metacaspase, putative 0.0096 0.0039 0.0051
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 1.5391 0.7446 1
Echinococcus granulosus g protein coupled receptor 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0028 0.0006 0.0117
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0027 0.0006 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0027 0.0006 0.0007
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0259 0.0118 0.0118
Echinococcus multilocularis serotonin receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis smad 0.0044 0.0014 0.0014
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.005 0.0017 0.0016
Brugia malayi Importin beta-1 subunit 0.0032 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0046 0.1505
Trypanosoma brucei oxidoreductase-like protein 0.0029 0.0006 0.0009
Brugia malayi paired box pox-meso protein 0.0019 0.0002 0.0002
Entamoeba histolytica ABC transporter, putative 0.0028 0.0006 0.0137
Mycobacterium tuberculosis Conserved protein 0.0027 0.0006 0.0163
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Giardia lamblia Hypothetical protein 0.0029 0.0006 0.0151
Echinococcus multilocularis retinol dehydrogenase 13 0.0029 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Onchocerca volvulus 0.0084 0.0033 0.0676
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0003 0.0003
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0127 0.0054 0.0054
Echinococcus granulosus neuropeptide receptor 0.0027 0.0005 0.0005
Schistosoma mansoni survival motor neuron protein 0.0363 0.0168 0.0168
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.005 0.0017 0.0022
Echinococcus granulosus hypothetical protein 0.0029 0.0006 0.0006
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0027 0.0006 0.0125
Onchocerca volvulus 0.0028 0.0006 0.0117
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0263 0.012 0.4186
Leishmania major cathepsin L-like protease 0.0074 0.0028 0.0037
Onchocerca volvulus 0.0019 0.0002 0.0027
Onchocerca volvulus 0.0269 0.0123 0.2539
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0027 0.0006 0.0125
Echinococcus multilocularis 0.0443 0.0207 0.0207
Giardia lamblia DNA topoisomerase II 0.0063 0.0023 0.0694
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Leishmania major protein kinase, putative 0.012 0.0051 0.0067
Echinococcus multilocularis cpg binding protein 0.0065 0.0024 0.0024
Schistosoma mansoni DNA topoisomerase type I 1.5391 0.7446 0.7446
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0111 0.0046 0.0046
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Echinococcus granulosus cpg binding protein 0.0065 0.0024 0.0024
Brugia malayi Pre-SET motif family protein 0.0468 0.0219 0.0219
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.023 0.0104 0.0104
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0029 0.0006 0.0008
Leishmania major DNA topoisomerase type IB small subunit 0.6864 0.3316 0.4453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0029 0.0006 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0237 0.0107 0.0143
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi DNA topoisomerase III 0.0284 0.013 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0178 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0027 0.0006 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0152
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0003 0.0003
Brugia malayi Cell death protein 3 precursor 0.0186 0.0082 0.0082
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0005 0.0005
Trypanosoma cruzi metacaspase 5, putative 0.0096 0.0039 0.0051
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0178 0.0079 0.0079
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0029 0.0006 0.0009
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0328 0.0151 0.5237
Schistosoma mansoni hypothetical protein 0.0344 0.0159 0.0158
Onchocerca volvulus 0.0062 0.0022 0.0456
Schistosoma mansoni multidrug resistance protein 0.0028 0.0006 0.0005
Brugia malayi Carboxylesterase family protein 0.0165 0.0072 0.0072
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0017 0.0017
Trichomonas vaginalis inositol monophosphatase, putative 0.0124 0.0053 0.1724
Schistosoma mansoni phosphatidylserine receptor 0.0045 0.0014 0.0014
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0003 0.0003
Loa Loa (eye worm) ctsf protein 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0533 0.0251 0.5188
Leishmania major pteridine reductase 1 0.0029 0.0006 0.0008
Echinococcus multilocularis ATP binding cassette sub family G 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0046 0.1505
Loa Loa (eye worm) hypothetical protein 0.0041 0.0012 0.0012
Schistosoma mansoni patched 1 0.0044 0.0014 0.0013
Onchocerca volvulus 0.0021 0.0003 0.0046
Echinococcus granulosus neuropeptide receptor 0.0027 0.0005 0.0005
Brugia malayi Pax transcription factor protein 2 0.1012 0.0483 0.0483
Onchocerca volvulus 0.0019 0.0002 0.0027
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0085 0.0033 0.114
Leishmania major importin beta-1 subunit, putative 0.0026 0.0005 0.0006
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0029 0.0006 0.0006
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0063 0.0023 0.0029
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0094 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0165 0.0072 0.0072
Schistosoma mansoni amine GPCR 0.0027 0.0005 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0033 0.0033
Toxoplasma gondii NADPH-glutathione reductase 0.005 0.0017 0.0015
Schistosoma mansoni hypothetical protein 0.0043 0.0013 0.0013
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0328 0.0151 0.5302
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0037 0.001 0.0577
Giardia lamblia Short-chain dehydrogenase, putative 0.0029 0.0006 0.0151
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0118 0.0049 0.0049
Mycobacterium leprae Conserved hypothetical protein 0.0027 0.0006 0.0023
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0019 0.0002 0.0001
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Toxoplasma gondii isocitrate dehydrogenase 0.0118 0.0049 0.0048
Trypanosoma cruzi DNA topoisomerase III, putative 0.0284 0.013 0.0173
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Leishmania major trypanothione reductase 0.0144 0.0062 0.0082
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0016 0.0016
Onchocerca volvulus Sepiapterin reductase homolog 0.0029 0.0006 0.0126
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0029 0.0006 0.0189
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0005 0.0005
Echinococcus multilocularis expressed protein 0.0037 0.001 0.001
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0029 0.0006 0.0159
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0029 0.0006 0.0126
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0178 0.0079 0.0079
Leishmania major hypothetical protein, conserved 0.0029 0.0006 0.0008
Leishmania major hypothetical protein, conserved 0.0024 0.0004 0.0004
Echinococcus multilocularis lamin 0.0086 0.0034 0.0034
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0014 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0647 0.0306 0.0306
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0029 0.0006 0.0193
Brugia malayi Dehydrogenases, short chain protein 30 0.0029 0.0006 0.0006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0178 0.0079 0.0079
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0029 0.0006 0.0151
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0037 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0016 0.0016
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0052 0.0018 0.0016
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0007 0.0007
Entamoeba histolytica DNA topoisomerase III, putative 0.0276 0.0126 0.4156
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0027 0.0006 0.0125
Loa Loa (eye worm) nuclear receptor NHR-67 0.0084 0.0033 0.0033
Plasmodium falciparum phd finger protein, putative 0.003 0.0007 0.0005
Echinococcus multilocularis expressed protein 0.043 0.0201 0.0201
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0013 0.0013
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.0006 0.013
Plasmodium falciparum histone acetyltransferase GCN5 0.0173 0.0076 0.0074
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0005 0.0005
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0005 0.0005
Schistosoma mansoni ferritin 0.0037 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0011 0.033
Brugia malayi Bromodomain containing protein 0.0046 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0171 0.0075 0.0075
Schistosoma mansoni opsin-like receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0034 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0005 0.0152
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.0106 0.0044 0.1484
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0178 0.0079 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Brugia malayi nuclear receptor NHR-88 0.0178 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Echinococcus multilocularis tumor protein p63 0.0389 0.0181 0.0181
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0017 0.0017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0025 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Echinococcus granulosus lamin 0.0086 0.0034 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Echinococcus granulosus expressed conserved protein 0.0097 0.0039 0.0039
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0089 0.0036 0.0036
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Brugia malayi nuclear receptor RXR 0.0084 0.0033 0.0033
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0029 0.0006 0.0193
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0005 0.0005
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0002 0.0002
Echinococcus granulosus aryl hydrocarbon receptor 0.0148 0.0064 0.0064
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0027 0.0006 0.0125
Schistosoma mansoni hypothetical protein 0.0043 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0178 0.0079 0.0079
Giardia lamblia DNA topoisomerase III 0.0144 0.0062 0.2009
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0092 0.3048
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0029 0.0006 0.0189
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0034 0.0034
Schistosoma mansoni cytochrome P450 0.0027 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0094 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0046 0.1505
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0011 0.0014
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0024 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0178 0.0079 0.0079
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0077 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis multidrug resistance associated protein 4 0.0021 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Mycobacterium ulcerans short-chain type oxidoreductase 0.0029 0.0006 0.0159
Plasmodium falciparum flap endonuclease 1 0.0029 0.0007 0.0005
Toxoplasma gondii oxidoreductase, putative 0.0029 0.0006 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0003 0.0003
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0063 0.0023 0.0021
Loa Loa (eye worm) dehydrogenase 0.0029 0.0006 0.0006
Echinococcus multilocularis chromobox protein 1 0.0067 0.0025 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Brugia malayi Melibiase family protein 0.0151 0.0065 0.0065
Trypanosoma cruzi metacaspase, putative 0.0096 0.0039 0.0051
Schistosoma mansoni myoglobin 1 0.0028 0.0006 0.0006
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0005 0.0005
Plasmodium vivax DNA topoisomerase 3, putative 0.0276 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Brugia malayi tailless protein 0.0084 0.0033 0.0033
Toxoplasma gondii LsmAD domain-containing protein 0.0138 0.0059 0.0058
Schistosoma mansoni carbonyl reductase 0.0029 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0029 0.0006 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0025 0.0025
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0029 0.0006 0.0008
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Trypanosoma cruzi short chain dehydrogenase, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis somatostatin receptor 0.0027 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.0027 0.0005 0.0005
Brugia malayi hypothetical protein 0.0028 0.0006 0.0006
Echinococcus granulosus peregrin 0.0046 0.0015 0.0015
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0011 0.0011
Brugia malayi hypothetical protein 0.0094 0.0038 0.0038
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0037 0.001 0.0332
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0014 0.0014
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0029 0.0006 0.0193
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0298 0.0137 0.4525
Brugia malayi Inositol-1 0.0124 0.0053 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0057 0.002 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0004 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0178 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0076
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0029 0.0006 0.0008
Trypanosoma brucei glucosidase, putative 0.0052 0.0018 0.0024
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0005 0.0141
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Loa Loa (eye worm) carboxylesterase 0.0028 0.0006 0.0006
Echinococcus granulosus JmjC domain containing protein 4 0.0045 0.0014 0.0014
Loa Loa (eye worm) Smad1 0.0044 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0138 0.0059 0.0059
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0019 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0012 0.0012
Echinococcus granulosus jun protein 0.0089 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0347 0.0161 0.5313
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0006 0.0171
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0027 0.0027
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0094 0.0038 0.0037
Loa Loa (eye worm) isocitrate dehydrogenase 0.0118 0.0049 0.0049
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0029 0.0006 0.0193
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0057
Trypanosoma cruzi multidrug resistance protein E, putative 0.0028 0.0006 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0087 0.2873
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0006 0.0006
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0029 0.0006 0.0057
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0002 0.0033
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0005 0.0005
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0022 0.0003 0.0002
Plasmodium falciparum JmjC domain-containing protein, putative 0.0045 0.0014 0.0012
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0011 0.0011
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.005 0.0017 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0138 0.0059 0.0058
Leishmania major hypothetical protein, conserved 0.0237 0.0107 0.0143
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0111 0.0046 0.1505
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0206 0.0092 0.0123
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0002 0.0027
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.002 0.002
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0027 0.0027
Schistosoma mansoni tsg101-related 0.005 0.0017 0.0016
Brugia malayi putative neuropeptide receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0029 0.0006 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0118 0.0049 0.0049
Brugia malayi Probable DNA topoisomerase II 0.0063 0.0023 0.0023
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.0039 0.1274
Schistosoma mansoni hypothetical protein 0.0027 0.0005 0.0005
Toxoplasma gondii carbonyl reductase 1, putative 0.0029 0.0006 0.0005
Mycobacterium ulcerans hypothetical protein 0.0024 0.0004 0.0073
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0206 0.0092 0.0092
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0062 0.0022 0.0022
Plasmodium vivax JmjC domain containing protein 0.0045 0.0014 0.0012
Onchocerca volvulus 0.0019 0.0002 0.0028
Schistosoma mansoni smad1 5 8 and 0.0044 0.0014 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0002 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0012 0.0385
Onchocerca volvulus 0.0028 0.0006 0.0113
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0106 0.0044 0.1439
Trypanosoma cruzi DNA topoisomerase III, putative 0.0284 0.013 0.0173
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Echinococcus granulosus TGF beta signal transducer SmadC 0.0044 0.0014 0.0014
Leishmania major alpha glucosidase II subunit, putative 0.0052 0.0018 0.0023
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0017 0.0017
Echinococcus multilocularis sex peptide receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0027 0.0005 0.0005
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0029 0.0006 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0178 0.0079 0.0079
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0029 0.0006 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 0.0118 0.0049 0.0049
Brugia malayi Flap endonuclease-1 0.0029 0.0007 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.004 0.0054
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0276 0.0126 0.4174
Brugia malayi oxidoreductase 0.0029 0.0006 0.0006
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.005 0.0017 0.05
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0027 0.0006 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0178 0.0079 0.0079
Toxoplasma gondii histone lysine methyltransferase SET1 0.0136 0.0058 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0052 0.0018 0.056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0214
Brugia malayi Glycosyl hydrolases family 31 protein 0.0052 0.0018 0.0018
Echinococcus granulosus expressed protein 0.043 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0002 0.0033
Echinococcus granulosus lysine specific demethylase 6a 0.0045 0.0014 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0022 0.0022
Loa Loa (eye worm) cysteine protease 0.0019 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0005 0.0005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0237 0.0107 0.0143
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 0.0027 0.0006 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0011 0.0011
Brugia malayi Matrixin family protein 0.0021 0.0003 0.0003
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0012 0.0012
Onchocerca volvulus 0.0084 0.0033 0.0676
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0007 0.0007
Trichomonas vaginalis glutathione reductase, putative 0.005 0.0017 0.0525
Loa Loa (eye worm) carboxylesterase 0.0165 0.0072 0.0072
Onchocerca volvulus 0.1012 0.0483 1
Brugia malayi larval opioid receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis Smad4 0.0044 0.0014 0.0014
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0005 0.0005
Mycobacterium ulcerans bacterioferritin BfrB 0.0037 0.001 0.0299
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0012 0.0012
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0006 0.0009
Schistosoma mansoni coup transcription factor 0.0178 0.0079 0.0078
Leishmania major hypothetical protein, conserved 0.0029 0.0006 0.0008
Echinococcus multilocularis retinol dehydrogenase 11 0.0029 0.0006 0.0006
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0006 0.0137
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0027 0.0006 0.0159
Onchocerca volvulus 0.0019 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0014 0.0437
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0002 0.0002
Mycobacterium ulcerans dehydrogenase 0.0029 0.0006 0.0159
Mycobacterium ulcerans dehydrogenase/reductase 0.0029 0.0006 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0284 0.013 0.013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0178 0.0079 0.0079
Schistosoma mansoni ferritin light chain 0.0037 0.001 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0023 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0347 0.0161 0.0161
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0008 0.0008
Echinococcus multilocularis peregrin 0.0046 0.0015 0.0015
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0005 0.0005
Brugia malayi GRF zinc finger family protein 0.007 0.0026 0.0026
Trypanosoma brucei DNA topoisomerase III, putative 0.0144 0.0062 0.0083
Leishmania major protein kinase, putative 0.0112 0.0047 0.0061
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0005 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0005 0.0005
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0003 0.0002
Loa Loa (eye worm) oxidoreductase 0.0029 0.0006 0.0006
Trypanosoma brucei metacaspase 5, putative 0.0096 0.0039 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis jumonji domain containing 1A 0.0045 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0111 0.0046 0.0046
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0029 0.0006 0.0008
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0022 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni DNA polymerase IV / kappa 0.0024 0.0004 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0005 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0028 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.0092 0.3042
Loa Loa (eye worm) inositol-1 0.0124 0.0053 0.0053
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0006 0.0008
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0011 0.0011
Trypanosoma cruzi cytochrome P450, putative 0.0065 0.0024 0.0031
Echinococcus granulosus neuroligin 0.0028 0.0006 0.0006
Onchocerca volvulus 0.005 0.0017 0.0337
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0178 0.0079 0.0079
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0045 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Schistosoma mansoni importin beta-1 0.0032 0.0008 0.0008
Schistosoma mansoni multidrug resistance protein 0.0028 0.0006 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Echinococcus multilocularis caspase 0.0255 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0014
Echinococcus granulosus jumonji domain containing 1A 0.0045 0.0014 0.0014
Brugia malayi hypothetical protein 0.0029 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Brugia malayi Melatonin receptor type 1A 0.0027 0.0005 0.0005
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0007 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Echinococcus granulosus mothers against decapentaplegic 2 0.002 0.0002 0.0002
Echinococcus granulosus mothers against decapentaplegic 6 0.002 0.0002 0.0002
Onchocerca volvulus 0.0029 0.0006 0.0126
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0029 0.0006 0.0005
Onchocerca volvulus 0.0079 0.0031 0.0631
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0006 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0005 0.0005
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0028 0.0006 0.0007
Brugia malayi Dopamine receptor protein 2 0.0027 0.0005 0.0005
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0022 0.0003 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0263 0.012 0.0119
Echinococcus granulosus acetylcholinesterase 0.0165 0.0072 0.0072
Echinococcus granulosus allatostatin A receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0038 0.0038
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0014 0.0014
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0255 0.0116 0.0116
Brugia malayi TAR-binding protein 0.0071 0.0027 0.0027
Schistosoma mansoni acetylcholinesterase 0.0028 0.0006 0.0005
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0017 0.0526
Leishmania major DNA topoisomerase III, putative 0.0144 0.0062 0.0082
Schistosoma mansoni paired box protein pax-6 0.0019 0.0002 0.0001
Trypanosoma brucei unspecified product 0.0099 0.004 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0017 0.0021
Trypanosoma brucei membrane transporter protein, putative 0.0139 0.006 0.008
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0002 0.0002
Plasmodium vivax metacaspase 1, putative 0.0096 0.0039 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Echinococcus multilocularis caspase 2 0.0186 0.0082 0.0082
Loa Loa (eye worm) DNA topoisomerase III 0.0284 0.013 0.013
Echinococcus granulosus hypothetical protein 0.0822 0.039 0.039
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0027 0.0006 0.0159
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.0007
Loa Loa (eye worm) ABC transporter 0.0018 0.0001 0.0001
Brugia malayi hypothetical protein 0.0037 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Echinococcus granulosus multidrug resistance associated protein 7 0.0028 0.0006 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0106 0.0044 0.0059
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0259 0.0118 0.0118
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0007 0.0163
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0118 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Brugia malayi hypothetical protein 0.0027 0.0005 0.0005
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0028 0.0006 0.0169
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0048 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0005 0.0005
Schistosoma mansoni Smad4 0.0044 0.0014 0.0013
Toxoplasma gondii SWI2/SNF2-containing protein 0.0047 0.0015 0.0014
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0029 0.0006 0.0193
Schistosoma mansoni smad 0.002 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.01 0.0041 0.0041
Brugia malayi DNA topoisomerase III beta-1 0.0144 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0011 0.0342
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.005 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0027 0.0005 0.0005
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0005 0.0005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0052 0.0018 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.005 0.0017 0.0022
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0604 0.0285 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.009 0.0036 0.0036
Schistosoma mansoni amine GPCR 0.0027 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0045 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Plasmodium falciparum metacaspase-like protein 0.0096 0.0039 0.0037
Schistosoma mansoni DNA topoisomerase type I 1.5391 0.7446 0.7446
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0006 0.0137
Brugia malayi MH1 domain containing protein 0.0024 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0039 0.1274
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0151 0.0065 0.0065
Brugia malayi Bromodomain containing protein 0.0019 0.0002 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0173 0.0076 0.2479
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0027 0.0036
Schistosoma mansoni adenoreceptor 0.0027 0.0005 0.0005
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0006 0.0159
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0077 0.003 0.003
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0005
Schistosoma mansoni multidrug resistance protein 0.0028 0.0006 0.0005
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0148 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0883 0.042 0.0419
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Echinococcus granulosus paired box gene 3/7 (eyeless, eyegone, twin of eyeless) 0.0019 0.0002 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0005 0.0005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0052 0.0018 0.0531
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0094 0.0038 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0017 0.0017
Schistosoma mansoni caspase-3 (C14 family) 0.0255 0.0116 0.0115
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0027 0.0006 0.0125
Loa Loa (eye worm) hypothetical protein 0.0087 0.0034 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0011 0.0322
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.0011
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0328 0.0151 0.5302
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0007 0.0008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0052 0.0018 0.056
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0006 0.0159
Toxoplasma gondii Alpha-galactosidase 0.0032 0.0008 0.0006
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0 0.0000068207
Brugia malayi glutathione reductase 0.0144 0.0062 0.0062
Toxoplasma gondii isocitrate dehydrogenase 0.0118 0.0049 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni carbonyl reductase 0.0029 0.0006 0.0006
Echinococcus multilocularis JmjC domain containing protein 4 0.0045 0.0014 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0015 0.0015
Trypanosoma cruzi DNA polymerase eta, putative 0.0079 0.0031 0.004
Plasmodium falciparum steroid dehydrogenase, putative 0.0029 0.0006 0.0005
Echinococcus granulosus microtubule associated protein 2 0.1503 0.072 0.072
Brugia malayi hypothetical protein 0.0029 0.0006 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0003 0.0003
Echinococcus multilocularis serotonin receptor 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0011 0.0353
Giardia lamblia Multidrug resistance-associated protein 1 0.0028 0.0006 0.0129
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0006 0.0159
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0024 0.0004 0.0004
Plasmodium vivax ABC transporter G family member 2, putative 0.0022 0.0003 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0011 0.0014
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.002 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0018 0.0024
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0027 0.0027
Trypanosoma brucei MATE efflux family protein, putative 0.0139 0.006 0.008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Loa Loa (eye worm) hypothetical protein 0.0094 0.0038 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0008 0.0011
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0063 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0084 0.0033 0.0033
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0002 0.0002
Echinococcus multilocularis muscleblind protein 1 0.0658 0.0311 0.0311
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0006 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Schistosoma mansoni neuropeptide receptor 0.0027 0.0005 0.0005
Entamoeba histolytica DNA topoisomerase II, putative 0.0063 0.0023 0.0701
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.001
Echinococcus granulosus multidrug resistance associated protein 4 0.0021 0.0003 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0019 0.0002 0.0002
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0006 0.0009
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0063 0.0023 0.0462
Brugia malayi hypothetical protein 0.1778 0.0853 0.0853
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.006 0.0079
Echinococcus granulosus kelch ECH associated protein 1 like 0.01 0.0041 0.0041
Trypanosoma cruzi polo-like protein kinase, putative 0.0206 0.0092 0.0123
Schistosoma mansoni aryl hydrocarbon receptor 0.038 0.0176 0.0176
Brugia malayi neuropeptide F receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0005 0.0005
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0006 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0014 0.0014
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0006 0.0137
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0025 0.0025
Leishmania major oxidoreductase-like protein 0.0029 0.0006 0.0008
Echinococcus multilocularis dna polymerase kappa 0.0106 0.0044 0.0044
Mycobacterium ulcerans oxidoreductase 0.0029 0.0006 0.0159
Brugia malayi hypothetical protein 0.0084 0.0033 0.0033
Giardia lamblia Multidrug resistance-associated protein 1 0.0027 0.0006 0.0122
Onchocerca volvulus Matrilysin homolog 0.0047 0.0015 0.0305
Echinococcus granulosus smad 0.0044 0.0014 0.0014
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.0007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor 0.0084 0.0033 0.0033
Schistosoma mansoni prokaryotic DNA topoisomerase 0.033 0.0152 0.0152
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0027 0.0006 0.0159
Leishmania major short chain dehydrogenase, putative 0.0029 0.0006 0.0008
Leishmania major cathepsin L-like protease 0.0074 0.0028 0.0037
Brugia malayi hypothetical protein 0.0037 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0028 0.0038
Echinococcus granulosus expressed protein 0.0037 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0144 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.001
Schistosoma mansoni amine GPCR 0.0027 0.0005 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0623 0.0294 0.0294
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0001 0.0001
Mycobacterium ulcerans monooxygenase 0.0028 0.0006 0.0144
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0006 0.0137
Onchocerca volvulus 0.0148 0.0064 0.1317
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0048 0.0016 0.0016
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0005 0.0005
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0029 0.0006 0.0009
Echinococcus granulosus kelch ECH associated protein 1 like 0.01 0.0041 0.0041
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0015 0.0305
Leishmania major hypothetical protein, conserved 0.0139 0.006 0.0079
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0025 0.0032
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0111 0.0046 0.1505
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0171 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0087 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.006 0.0079
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0365 0.0169 0.5928
Brugia malayi Globin family protein 0.0028 0.0006 0.0006
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0028 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Chlamydia trachomatis DNA gyrase subunit B 0.0063 0.0023 0.0465
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0017 0.0995
Onchocerca volvulus Huntingtin homolog 0.0405 0.0188 0.3899
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0077 0.003 0.003
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0033 0.0033
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0027 0.0006 0.0005
Brugia malayi MH2 domain containing protein 0.0044 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0074 0.0028 0.0028
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0124 0.0053 0.1787
Echinococcus multilocularis paired box protein pax 1 0.0019 0.0002 0.0002
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0084 0.0033 0.0033
Loa Loa (eye worm) MH1 domain-containing protein 0.002 0.0002 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.1503 0.072 0.072
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0111 0.0046 0.0046
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0029 0.0006 0.0193
Onchocerca volvulus 0.007 0.0026 0.0536
Trichomonas vaginalis hypothetical protein 0.0036 0.001 0.0299
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0005 0.0005
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0029 0.0006 0.0159
Echinococcus granulosus FTZ F1 alpha 0.0178 0.0079 0.0079
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0171 0.0075 0.0075
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0328 0.0151 0.5302
Echinococcus granulosus g protein coupled receptor 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0112 0.0047 0.0061
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Echinococcus multilocularis conserved hypothetical protein 0.0029 0.0006 0.0006
Leishmania major mitochondrial DNA topoisomerase II 0.0063 0.0023 0.0029
Leishmania major DNA polymerase kappa, putative 0.0085 0.0033 0.0044
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0006 0.0193
Trypanosoma brucei ATP-binding cassette protein, putative 0.0022 0.0003 0.0004
Echinococcus granulosus oxidoreductase 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0178 0.0079 0.0079
Echinococcus granulosus zinc finger protein 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0017 0.0556
Leishmania major short chain dehydrogenase/reductase, putative 0.0029 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Schistosoma mansoni ferritin 0.0037 0.001 0.001
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0005 0.0141
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0328 0.0151 0.5302
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0003
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0027 0.0027
Mycobacterium ulcerans DNA topoisomerase I 0.0276 0.0126 0.4385
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0028 0.0006 0.0008
Echinococcus multilocularis ferritin 0.0037 0.001 0.001
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0075 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.0019 0.0002 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0468 0.0219 0.0219
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0029 0.0006 0.0189
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0006 0.0006
Echinococcus granulosus geminin 0.1455 0.0697 0.0697
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0012 0.0012
Echinococcus multilocularis mothers against decapentaplegic 6 0.002 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0017 0.0556
Schistosoma mansoni zinc finger protein 0.0084 0.0033 0.0033
Giardia lamblia Multidrug resistance-associated protein 1 0.0028 0.0006 0.0129
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0005 0.0006
Echinococcus multilocularis muscleblind protein 0.0658 0.0311 0.0311
Echinococcus granulosus g protein coupled receptor 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.0028 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0006 0.0126
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0003 0.0003
Onchocerca volvulus 0.0028 0.0006 0.0117
Plasmodium falciparum importin beta, putative 0.0032 0.0008 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0111 0.0046 0.1505
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0006 0.0159
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0027 0.0006 0.0125
Brugia malayi Cathepsin L-like precursor 0.0019 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0005 0.0125
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0022 0.0003 0.0003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0062 0.0022 0.0022
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.005 0.0017 0.0017
Entamoeba histolytica serine/threonine protein kinase, putative 0.0206 0.0092 0.3026
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Onchocerca volvulus 0.0028 0.0006 0.0117
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0006 0.0189
Brugia malayi nuclear hormone receptor 0.0084 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0178 0.0079 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0106 0.0044 0.0059
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0027 0.0027
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0206 0.0092 0.0092
Trypanosoma cruzi PAB1-binding protein , putative 0.0138 0.0059 0.0079
Brugia malayi hypothetical protein 0.0028 0.0006 0.0006
Brugia malayi GnHR receptor homolog 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0019 0.0002 0.0027
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0017 0.0526
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0012 0.0012
Loa Loa (eye worm) vab-3 0.0019 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0637 0.0301 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0052 0.0018 0.0018
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0139 0.006 0.006
Onchocerca volvulus Matrilysin homolog 0.0021 0.0003 0.0046
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0006 0.0193
Echinococcus multilocularis jun protein 0.0089 0.0036 0.0036
Loa Loa (eye worm) CYP4Cod1 0.0065 0.0024 0.0024
Onchocerca volvulus 0.0029 0.0006 0.0126
Schistosoma mansoni hypothetical protein 0.0363 0.0168 0.0168
Onchocerca volvulus 0.0019 0.0002 0.0023
Brugia malayi Globin family protein 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0084 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0017 0.0021
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0027 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0005 0.0005

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2 nM Binding affinity against delta opioid receptor in mouse hot plate test ChEMBL. 15482911
Ki (binding) = 2.6 nM Binding affinity against mu opioid receptor in mouse hot plate test ChEMBL. 15482911
Ki (binding) = 2.6 nM Binding affinity against mu opioid receptor in mouse hot plate test ChEMBL. 15482911
Ratio (binding) = 1.3 Ratio of binding affinity against mu to that of delta opioid receptor ChEMBL. 15482911
Ratio (binding) = 1.3 Ratio of binding affinity against mu to that of delta opioid receptor ChEMBL. 15482911

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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