Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Androgen Receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3551 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Brugia malayi | amidase | 0.0549 | 0.1385 | 0.1385 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.06 | 0.1532 | 1 |
Trypanosoma cruzi | amidase, putative | 0.0066 | 0 | 0.5 |
Trypanosoma cruzi | amidase, putative | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.3551 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.06 | 0.1532 | 0.1532 |
Brugia malayi | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Leishmania major | hypothetical protein, conserved | 0.0066 | 0 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.06 | 0.1532 | 0.1532 |
Brugia malayi | Carboxylesterase family protein | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.3551 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.06 | 0.1532 | 0.1532 |
Schistosoma mansoni | amidase | 0.0549 | 0.1385 | 0.1385 |
Echinococcus granulosus | acetylcholinesterase | 0.3551 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3551 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.3551 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.06 | 0.1532 | 0.1532 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0066 | 0 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.06 | 0.1532 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.06 | 0.1532 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0549 | 0.1385 | 0.1385 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | carboxylesterase | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.0549 | 0.1385 | 0.1385 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0066 | 0 | 0.5 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0066 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.06 | 0.1532 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.06 | 0.1532 | 0.1532 |
Onchocerca volvulus | 0.06 | 0.1532 | 0.5 | |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0549 | 0.1385 | 0.1385 |
Schistosoma mansoni | gliotactin | 0.06 | 0.1532 | 0.1532 |
Trypanosoma brucei | fatty-acid amide hydrolase, putative | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0549 | 0.1385 | 0.1385 |
Brugia malayi | Carboxylesterase family protein | 0.3551 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3551 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.06 | 0.1532 | 0.1532 |
Onchocerca volvulus | 0.06 | 0.1532 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.06 | 0.1532 | 0.1532 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0066 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.06 | 0.1532 | 0.1532 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Schistosoma mansoni | acetylcholinesterase | 0.06 | 0.1532 | 0.1532 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.06 | 0.1532 | 0.1532 |
Echinococcus multilocularis | acetylcholinesterase | 0.3551 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.06 | 0.1532 | 0.1532 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.06 | 0.1532 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.06 | 0.1532 | 0.5 |
Echinococcus granulosus | neuroligin | 0.06 | 0.1532 | 0.1532 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0066 | 0 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.06 | 0.1532 | 0.1532 |
Echinococcus granulosus | carboxylesterase 5A | 0.3551 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.3551 | 1 | 1 |
Onchocerca volvulus | 0.06 | 0.1532 | 0.5 | |
Onchocerca volvulus | 0.06 | 0.1532 | 0.5 | |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0549 | 0.1385 | 0.1385 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3551 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | carboxylesterase | 0.06 | 0.1532 | 0.1532 |
Loa Loa (eye worm) | hypothetical protein | 0.06 | 0.1532 | 0.1532 |
Onchocerca volvulus | 0.06 | 0.1532 | 0.5 | |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0549 | 0.1385 | 0.1385 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.