Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0396 | 0.1415 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0057 | 0.1694 | 0.1756 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0087 | 0.2776 | 0.2386 |
Brugia malayi | G-protein coupled receptor | 0.0057 | 0.1694 | 0.1488 |
Brugia malayi | ORL1-like opioid receptor | 0.0057 | 0.1694 | 0.1488 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0269 | 0.9447 | 1 |
Leishmania major | AMP deaminase, putative,adenosine monophosphate deaminase-like protein | 0.0088 | 0.28 | 0.2689 |
Toxoplasma gondii | AMP deaminase | 0.0088 | 0.28 | 0.2964 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0022 | 0.0396 | 0.0377 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0687 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.6235 | 0.6235 |
Brugia malayi | Serotonin receptor | 0.0057 | 0.1694 | 0.1488 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0047 | 0.1326 | 0.1404 |
Echinococcus multilocularis | neuropeptide receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0148 | 0.5017 | 0.529 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0047 | 0.1326 | 0.1365 |
Brugia malayi | larval opioid receptor | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0148 | 0.5017 | 0.4894 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0656 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0269 | 0.9447 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0057 | 0.1694 | 0.1756 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.06 | 0.0635 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1694 | 0.1793 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.06 | 0.0269 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0355 | 0.0333 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0396 | 0.0159 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0269 | 0.9447 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0269 | 0.9447 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0022 | 0.0396 | 0.0377 |
Brugia malayi | neuropeptide F receptor | 0.0057 | 0.1694 | 0.1488 |
Entamoeba histolytica | AMP deaminase, putative | 0.0088 | 0.28 | 0.2964 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0148 | 0.5017 | 0.529 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | serotonin receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0057 | 0.1694 | 0.1756 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0355 | 0.0355 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0161 | 0.5497 | 0.5819 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.5152 | 0.5434 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.06 | 0.0635 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.00000000033317 | 0.00000000033317 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2663 |
Echinococcus granulosus | g-protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0022 | 0.0396 | 0.0499 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma brucei | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0088 | 0.28 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | RE15519p | 0.0057 | 0.1694 | 0.1488 |
Entamoeba histolytica | recQ family helicase, putative | 0.0022 | 0.0396 | 0.0419 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0057 | 0.1678 | 0.1455 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.0355 | 0.0376 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0148 | 0.5017 | 0.5311 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1694 | 0.1793 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0668 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.5749 | 0.5749 |
Schistosoma mansoni | DNA helicase recq1 | 0.0022 | 0.0396 | 0.0419 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0057 | 0.1694 | 0.1488 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.2776 | 0.2939 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Brugia malayi | hypothetical protein | 0.0028 | 0.06 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.5152 | 0.5152 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2908 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Schistosoma mansoni | adenosine deaminase-related | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | orexin receptor type 2 | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0022 | 0.0396 | 0.0377 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0087 | 0.2776 | 0.2939 |
Brugia malayi | putative neuropeptide receptor | 0.0057 | 0.1694 | 0.1488 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0259 | 0.0259 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0057 | 0.1694 | 0.1756 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0057 | 0.1678 | 0.1132 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0396 | 0.0419 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0057 | 0.1694 | 0.1694 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.06 | 0.0269 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0088 | 0.28 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0057 | 0.1694 | 0.1756 |
Leishmania major | adenine aminohydrolase | 0.0269 | 0.9447 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | G-protein coupled receptor | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | bloom syndrome protein | 0.0022 | 0.0396 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.2776 | 0.2776 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1694 | 0.1793 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0088 | 0.28 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.1181 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | acetyltransferase | 0.0161 | 0.5497 | 0.5497 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0161 | 0.5497 | 0.5386 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0042 | 0.0044 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.6235 | 0.6235 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0047 | 0.1326 | 0.1068 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | hypothetical protein | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | AMP deaminase 2 | 0.0088 | 0.28 | 0.2932 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Onchocerca volvulus | AMP deaminase 2 homolog | 0.0088 | 0.28 | 0.1426 |
Entamoeba histolytica | AMP deaminase, putative | 0.0088 | 0.28 | 0.2964 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0057 | 0.1694 | 0.1488 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0057 | 0.1694 | 0.1756 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2939 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2663 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Brugia malayi | Melatonin receptor type 1A | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | serotonin receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma brucei | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0057 | 0.1694 | 0.1756 |
Treponema pallidum | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.6235 | 0.6235 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.6497 | 0.6877 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0396 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1694 | 0.1793 |
Leishmania major | adenosine monophosphate deaminase, putative,AMP deaminase, putative | 0.0088 | 0.28 | 0.2689 |
Plasmodium vivax | adenosine deaminase, putative | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0148 | 0.5017 | 0.5311 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0269 | 0.9447 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0396 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | neuropeptide receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Brugia malayi | Dopamine receptor protein 2 | 0.0057 | 0.1694 | 0.1488 |
Echinococcus granulosus | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0284 | 1 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | histamine h1 receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.06 | 0.06 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0355 | 0.0376 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0396 | 0.0159 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0355 | 0.1268 |
Plasmodium falciparum | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Onchocerca volvulus | 0.0168 | 0.5749 | 0.523 | |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0047 | 0.1326 | 0.1404 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0057 | 0.1678 | 0.174 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1694 | 0.1793 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.06 | 0.0269 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Leishmania major | AMP deaminase, putative | 0.0088 | 0.28 | 0.2689 |
Schistosoma mansoni | DNA helicase recq5 | 0.0022 | 0.0396 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.6235 | 0.6235 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0022 | 0.0396 | 0.0045 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | Dopamine receptor protein 1 | 0.0057 | 0.1694 | 0.1488 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | sex peptide receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0161 | 0.5497 | 0.5801 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | fmrfamide receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | geminin | 0.0188 | 0.6497 | 0.6863 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | neuropeptide receptor | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0355 | 0.1268 |
Echinococcus granulosus | neuropeptide s receptor | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.5152 | 0.5032 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1694 | 0.1793 |
Leishmania major | hypothetical protein, conserved | 0.0088 | 0.28 | 0.2689 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1694 | 0.1793 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0687 | 0.0727 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0022 | 0.0396 | 0.0396 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.6497 | 0.6877 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0396 | 0.0045 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | fmrfamide receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0355 | 0.0376 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Brugia malayi | Serotonin receptor | 0.0057 | 0.1694 | 0.1488 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0355 | 0.0116 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0396 | 0.0045 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0355 | 0.0376 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0148 | 0.5017 | 0.5311 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | adenosine monophosphate deaminase | 0.0088 | 0.28 | 0.2622 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0687 | 0.0727 |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.9447 | 0.9447 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.06 | 0.1002 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.06 | 0.2142 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.06 | 0.2142 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0022 | 0.0396 | 0.0159 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1694 | 0.1756 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.2776 | 0.2939 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0269 | 0.9447 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | AMP deaminase | 0.0088 | 0.28 | 0.28 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0057 | 0.1694 | 0.1488 |
Schistosoma mansoni | AMP deaminase | 0.0088 | 0.28 | 0.2964 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0057 | 0.1694 | 0.1756 |
Onchocerca volvulus | 0.0088 | 0.28 | 0.1426 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0396 | 0.0045 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0656 | 0.0656 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2663 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus granulosus | serotonin receptor | 0.0057 | 0.1694 | 0.1756 |
Mycobacterium ulcerans | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0047 | 0.1326 | 0.1404 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.2908 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0057 | 0.1678 | 0.1455 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0057 | 0.1694 | 0.1793 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0396 | 0.0169 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Trypanosoma brucei | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0087 | 0.2776 | 0.2939 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0029 | 0.0656 | 0.2343 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0029 | 0.0656 | 0.0331 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0148 | 0.5017 | 0.529 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0057 | 0.1694 | 0.1488 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0088 | 0.28 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0148 | 0.5017 | 0.529 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0269 | 0.9447 | 1 |
Brugia malayi | Dopamine receptor | 0.0057 | 0.1694 | 0.1488 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0355 | 0.0333 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0022 | 0.0396 | 0.0396 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.5152 | 0.5434 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0057 | 0.1694 | 0.1793 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0057 | 0.1694 | 0.1756 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0088 | 0.28 | 1 |
Plasmodium vivax | adenosine/AMP deaminase, putative | 0.0088 | 0.28 | 0.2964 |
Leishmania major | cytochrome p450-like protein | 0.0029 | 0.0656 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.1181 | 0.0909 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0022 | 0.0396 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.5152 | 0.5152 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0269 | 0.9447 | 0.9433 |
Echinococcus multilocularis | neuropeptide receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | adenosine deaminase | 0.0269 | 0.9447 | 1 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0269 | 0.9447 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | G protein-coupled receptor | 0.0057 | 0.1694 | 0.1488 |
Echinococcus multilocularis | AMP deaminase 2 | 0.0088 | 0.28 | 0.2932 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | AKH receptor | 0.0057 | 0.1694 | 0.1488 |
Brugia malayi | GnHR receptor homolog | 0.0057 | 0.1694 | 0.1488 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0047 | 0.1326 | 0.1068 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0057 | 0.1694 | 0.1793 |
Brugia malayi | hypothetical protein | 0.0168 | 0.5749 | 0.5644 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0029 | 0.0656 | 0.2343 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0057 | 0.1694 | 0.1793 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0656 | 0.0425 |
Echinococcus multilocularis | geminin | 0.0188 | 0.6497 | 0.6863 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0355 | 0.0376 |
Brugia malayi | Probable ClpP-like protease | 0.0087 | 0.2776 | 0.2598 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0656 | 0.0656 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.28 | 0.28 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1694 | 0.1756 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0687 | 0.0365 |
Echinococcus granulosus | allatostatin A receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0355 | 0.0376 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | bloom syndrome protein | 0.0022 | 0.0396 | 0.0377 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1694 | 0.1488 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0148 | 0.5017 | 0.5017 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0043 | 0.1181 | 0.125 |
Trypanosoma brucei | cytochrome P450, putative | 0.0029 | 0.0656 | 0.1231 |
Brugia malayi | neuropeptide F receptor | 0.0057 | 0.1694 | 0.1488 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0157 | 0.5332 | 0.5624 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0057 | 0.1694 | 0.1793 |
Schistosoma mansoni | myosin xvIII | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.5152 | 0.5434 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1694 | 0.1756 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0057 | 0.1694 | 0.1488 |
Echinococcus granulosus | sex peptide receptor | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1694 | 0.1756 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1694 | 0.1793 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0022 | 0.0396 | 0.0045 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0668 | 0.0668 |
Echinococcus multilocularis | allatostatin A receptor | 0.0057 | 0.1694 | 0.1756 |
Plasmodium falciparum | AMP deaminase, putative | 0.0088 | 0.28 | 0.2689 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0022 | 0.0396 | 0.0045 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0057 | 0.1678 | 0.174 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0057 | 0.1694 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1694 | 0.1694 |
Echinococcus granulosus | somatostatin receptor | 0.0057 | 0.1694 | 0.1756 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0057 | 0.1694 | 0.1793 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.2776 | 0.5 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0057 | 0.1694 | 0.1756 |
Leishmania major | AMP deaminase, putative,amp deaminase-like protein | 0.0088 | 0.28 | 0.2689 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0057 | 0.1694 | 0.1756 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0029 | 0.0656 | 0.0656 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1694 | 0.1793 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 68 uM | Inhibitory concentration required against human cytomegalovirus (HCMV) expressed in HFF cells was determined by plaque reduction assay | ChEMBL. | 15509176 |
IC50 (functional) | = 90 uM | Inhibitory concentration required against herpes simplex virus type-1 (HSV-1) expressed in BSC-1 cells was determined by ELISA assay | ChEMBL. | 15509176 |
IC50 (functional) | > 100 uM | Cytotoxicity produced in stationary HFF cells was determined by microscopic inspection of uninfected cells | ChEMBL. | 15509176 |
IC50 (functional) | > 100 uM | Cytotoxicity of the compound against KB cells was determined by crystal violet staining and spectrophotometric quantitation of dye eluted from stained cells | ChEMBL. | 15509176 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.