Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Mus musculus | opioid receptor, mu 1 | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 280 nM | Binding affinity against delta opioid receptor in mouse hot plate test | ChEMBL. | 15482911 |
Ki (binding) | = 480 nM | Binding affinity against mu opioid receptor in mouse hot plate test | ChEMBL. | 15482911 |
Ki (binding) | = 480 nM | Binding affinity against mu opioid receptor in mouse hot plate test | ChEMBL. | 15482911 |
Ratio (binding) | = 1.7 | Ratio of binding affinity against mu to that of delta opioid receptor | ChEMBL. | 15482911 |
Ratio (binding) | = 1.7 | Ratio of binding affinity against mu to that of delta opioid receptor | ChEMBL. | 15482911 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.