Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0536 | 0.5596 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0536 | 0.5596 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0536 | 0.5596 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0536 | 0.5596 | 0.5099 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0536 | 0.5596 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Trypanosoma brucei | phospholipase A1, putative | 0.0704 | 1 | 0.5 |
Onchocerca volvulus | 0.0704 | 1 | 1 | |
Mycobacterium ulcerans | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0536 | 0.5596 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0536 | 0.5596 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Onchocerca volvulus | 0.0704 | 1 | 1 | |
Plasmodium falciparum | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0536 | 0.5596 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0536 | 0.5596 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0536 | 0.5596 | 0.5 |
Onchocerca volvulus | 0.0704 | 1 | 1 | |
Loa Loa (eye worm) | platelet-activating factor acetylhydrolase | 0.0704 | 1 | 1 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0704 | 1 | 1 |
Leishmania major | phospholipase A1, putative | 0.0704 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0536 | 0.5596 | 0.5 |
Trypanosoma cruzi | phospholipase A1, putative | 0.0704 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0536 | 0.5596 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | Percent inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase at 1.1 uM | ChEMBL. | 15501060 |
Inhibition (binding) | = 0 % | Percent inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase at 1.1 uM | ChEMBL. | 15501060 |
Inhibition (binding) | = 13 % | Percent inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase at 1.1 uM | ChEMBL. | 15501060 |
Inhibition (binding) | = 13 % | Percent inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferase at 1.1 uM | ChEMBL. | 15501060 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.