Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | histone deacetylase, putative | 0.029 | 0.3677 | 0.363 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0095 | 0.0959 | 0.0892 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0742 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.029 | 0.3677 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0321 | 0.4107 | 0.4107 |
Giardia lamblia | Cathepsin B precursor | 0.0095 | 0.0959 | 0.2402 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0032 | 0.0074 | 0.0053 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0362 | 0.4686 | 0.4633 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0158 | 0.1833 | 0.1833 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0034 | 0.0013 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0149 | 0.1706 | 0.1706 |
Trypanosoma brucei | histone deacetylase 2 | 0.0158 | 0.1833 | 0.175 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.021 | 0.2562 | 0.2552 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.029 | 0.3677 | 0.363 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0169 | 0.1988 | 0.1977 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0149 | 0.1706 | 0.1695 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0901 | 0.0882 |
Echinococcus granulosus | histone deacetylase 6 | 0.0362 | 0.4686 | 0.4675 |
Leishmania major | pyruvate kinase | 0.0034 | 0.01 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0756 | 0.0743 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0079 | 0.073 | 0.073 |
Schistosoma mansoni | tyrosine kinase | 0.0032 | 0.0074 | 0.0053 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0039 | 0.0167 | 0.0154 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0021 | 0.0007 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0158 | 0.1833 | 0.1772 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0326 | 0.4182 | 0.4174 |
Loa Loa (eye worm) | histone deacetylase | 0.0362 | 0.4686 | 0.4679 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0062 | 0.0486 | 0.0466 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0063 | 0.0503 | 0.0503 |
Brugia malayi | histone deacetylase 11 | 0.0326 | 0.4182 | 0.417 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0081 | 0.0756 | 0.0737 |
Leishmania major | pyruvate kinase | 0.0034 | 0.01 | 0.0027 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.01 | 0.0087 |
Echinococcus granulosus | calpain A | 0.024 | 0.298 | 0.2965 |
Brugia malayi | gamma-secretase subunit aph-1 | 0.0237 | 0.2944 | 0.2929 |
Trypanosoma brucei | calpain-like protein, putative | 0.0087 | 0.0835 | 0.0743 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0034 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.2115 | 0.2098 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0317 | 0.4058 | 0.4058 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0362 | 0.4686 | 0.4679 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1988 | 0.1977 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.1974 | 0.1963 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2139 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0081 | 0.0756 | 0.0756 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.024 | 0.298 | 0.298 |
Giardia lamblia | Histone deacetylase | 0.029 | 0.3677 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0116 | 0.0043 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0081 | 0.0756 | 0.0756 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0368 | 0.477 | 0.4759 |
Loa Loa (eye worm) | glutamate receptor | 0.0069 | 0.0596 | 0.0583 |
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.0237 | 0.2944 | 0.2929 |
Echinococcus granulosus | gamma secretase subunit aph 1 | 0.0237 | 0.2944 | 0.2929 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0116 | 0.0102 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD+) | 0.009 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0087 | 0.0835 | 0.0816 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0421 | 0.0408 |
Entamoeba histolytica | tartrate dehydrogenase, putative | 0.009 | 0.0885 | 0.2251 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.009 | 0.0885 | 0.0866 |
Schistosoma mansoni | glutamate receptor kainate | 0.0149 | 0.1706 | 0.1689 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0116 | 0.0198 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0116 | 0.0198 |
Mycobacterium tuberculosis | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) | 0.009 | 0.0885 | 0.0793 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0116 | 0.0043 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | 0.009 | 0.0885 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Onchocerca volvulus | 0.0035 | 0.0116 | 0.0523 | |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0095 | 0.0959 | 0.0868 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0266 | 0.3347 | 0.3333 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0116 | 0.0016 |
Loa Loa (eye worm) | calpain family protein 1 | 0.023 | 0.2834 | 0.2825 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0901 | 0.0882 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0756 | 0.0737 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0289 | 0.3669 | 0.3656 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.073 | 0.0717 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0116 | 0.0116 |
Echinococcus multilocularis | calpain 5 | 0.0087 | 0.0835 | 0.0835 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0116 | 0.0198 |
Echinococcus multilocularis | tyrosine kinase | 0.0032 | 0.0074 | 0.0074 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0742 | 1 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0742 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0126 | 0.1385 | 0.1385 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1833 | 0.1821 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0116 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Schistosoma mansoni | Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial | 0.009 | 0.0885 | 0.0866 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0048 | 0.0301 | 0.028 |
Entamoeba histolytica | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Trypanosoma cruzi | kinesin, putative | 0.0061 | 0.0471 | 0.0401 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0081 | 0.0756 | 0.0737 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0116 | 0.0016 |
Echinococcus granulosus | calpain A | 0.0087 | 0.0835 | 0.0816 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0289 | 0.3669 | 0.3656 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | 0.009 | 0.0885 | 0.0866 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0034 | 0.002 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0363 | 0.4696 | 0.4685 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.01 | 0.0438 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0321 | 0.4107 | 0.4095 |
Echinococcus granulosus | histone deacetylase 7 | 0.0362 | 0.4686 | 0.4675 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0116 | 0.0095 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0901 | 0.0901 |
Schistosoma mansoni | integrin beta subunit | 0.0209 | 0.2541 | 0.2526 |
Leishmania major | histone deacetylase, putative | 0.029 | 0.3677 | 0.363 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2139 |
Echinococcus granulosus | glutamate receptor NMDA | 0.024 | 0.2984 | 0.297 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0317 | 0.4058 | 0.4046 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.01 | 0.0079 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.01 | 0.0087 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0901 | 0.0888 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0116 | 0.0198 |
Schistosoma mansoni | calpain (C02 family) | 0.0087 | 0.0835 | 0.0816 |
Leishmania major | isocitrate dehydrogenase, putative | 0.009 | 0.0885 | 0.0817 |
Echinococcus multilocularis | caspase 2 | 0.0062 | 0.0486 | 0.0486 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0087 | 0.0835 | 0.0835 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus granulosus | geminin | 0.0178 | 0.2115 | 0.2098 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0362 | 0.4686 | 0.4686 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0149 | 0.1706 | 0.1689 |
Leishmania major | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4647 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.01 | 0.01 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.01 | 0.0438 |
Brugia malayi | hypothetical protein | 0.0057 | 0.0421 | 0.0401 |
Echinococcus multilocularis | geminin | 0.0178 | 0.2115 | 0.2115 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0055 | 0.0395 | 0.0375 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0368 | 0.477 | 0.477 |
Echinococcus granulosus | isocitrate dehydrogenase NAD | 0.009 | 0.0885 | 0.0866 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0116 | 0.0016 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0116 | 0.0043 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0069 | 0.0596 | 0.0577 |
Brugia malayi | Isocitrate dehydrogenase subunit gamma, mitochondrial precursor | 0.009 | 0.0885 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0095 | 0.0959 | 0.2402 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0047 | 0.028 | 0.026 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0116 | 0.0198 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0289 | 0.3669 | 0.3656 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.01 | 0.0079 |
Onchocerca volvulus | 0.0032 | 0.0074 | 0.0292 | |
Echinococcus granulosus | nmda type glutamate receptor | 0.0272 | 0.3433 | 0.342 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0317 | 0.4058 | 0.4046 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Loa Loa (eye worm) | cathepsin B | 0.0095 | 0.0959 | 0.0947 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0081 | 0.0756 | 0.0737 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0493 | 0.0473 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0181 | 0.2156 | 0.2156 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0039 | 0.0167 | 0.0154 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4647 |
Trypanosoma brucei | antigen, putative | 0.0087 | 0.0835 | 0.0743 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0116 | 0.0095 |
Leishmania major | kinesin, putative | 0.0061 | 0.0471 | 0.0401 |
Trypanosoma brucei | histone deacetylase 4 | 0.0362 | 0.4686 | 0.4633 |
Echinococcus multilocularis | cathepsin b | 0.0289 | 0.3669 | 0.3669 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0032 | 0.0074 | 0.0053 |
Schistosoma mansoni | histone deacetylase | 0.029 | 0.3677 | 0.3663 |
Giardia lamblia | Cathepsin B precursor | 0.0095 | 0.0959 | 0.2402 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0057 | 0.0057 |
Echinococcus granulosus | histone deacetylase 3 | 0.029 | 0.3677 | 0.3663 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.01 | 0.0087 |
Plasmodium falciparum | histone deacetylase 2 | 0.0362 | 0.4686 | 0.4633 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.2479 | 0.2468 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.2115 | 0.2098 |
Echinococcus granulosus | histone deacetylase 6 | 0.0362 | 0.4686 | 0.4675 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0092 | 0.0918 | 0.085 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.2762 | 0.2689 |
Brugia malayi | Isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0181 | 0.2156 | 0.2139 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD) subunit | 0.009 | 0.0885 | 0.0885 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0289 | 0.3669 | 0.3656 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.01 | 0.0087 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0087 | 0.0835 | 0.0816 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.024 | 0.2984 | 0.2984 |
Onchocerca volvulus | 0.0035 | 0.0116 | 0.0523 | |
Echinococcus multilocularis | hypothetical protein | 0.0087 | 0.0835 | 0.0835 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0032 | 0.0074 | 0.0074 |
Echinococcus multilocularis | cathepsin b | 0.0289 | 0.3669 | 0.3669 |
Echinococcus granulosus | glutamate receptor 2 | 0.0126 | 0.1385 | 0.1367 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0032 | 0.0074 | 0.0053 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.009 | 0.0885 | 0.0866 |
Trypanosoma brucei | Aph-1 protein, putative | 0.0092 | 0.0918 | 0.0826 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0149 | 0.1706 | 0.1689 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0486 | 0.0473 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0092 | 0.0918 | 0.085 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0116 | 0.0095 |
Onchocerca volvulus | 0.0029 | 0.0034 | 0.0073 | |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.024 | 0.298 | 0.2965 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0149 | 0.1706 | 0.1689 |
Schistosoma mansoni | protein kinase | 0.0032 | 0.0074 | 0.0053 |
Mycobacterium leprae | PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) | 0.009 | 0.0885 | 1 |
Brugia malayi | calpain 5 | 0.0061 | 0.0471 | 0.0451 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0039 | 0.0167 | 0.0147 |
Echinococcus granulosus | isocitrate dehydrogenase NAD subunit | 0.009 | 0.0885 | 0.0866 |
Echinococcus multilocularis | calpain A | 0.024 | 0.298 | 0.298 |
Plasmodium falciparum | histone deacetylase 1 | 0.029 | 0.3677 | 0.3613 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.0061 | 0.0471 | 0.1104 |
Brugia malayi | Histone deacetylase family protein | 0.0362 | 0.4686 | 0.4675 |
Loa Loa (eye worm) | calpain 5 | 0.0061 | 0.0471 | 0.0458 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.01 | 0.0438 |
Plasmodium vivax | histone deacetylase, putative | 0.0326 | 0.4182 | 0.4123 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0885 | 0.0872 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0087 | 0.0835 | 0.0767 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.04 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.3669 | 0.366 |
Trypanosoma brucei | calpain-like protein, putative | 0.0087 | 0.0835 | 0.0743 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0362 | 0.4686 | 0.4675 |
Loa Loa (eye worm) | hypothetical protein | 0.029 | 0.3677 | 0.3668 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.029 | 0.3677 | 0.3668 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0362 | 0.4686 | 0.4633 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.024 | 0.298 | 0.2965 |
Plasmodium vivax | calpain, putative | 0.0087 | 0.0835 | 0.0743 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0116 | 0.0198 |
Brugia malayi | Histone deacetylase family protein | 0.0362 | 0.4686 | 0.4675 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0395 | 0.0375 |
Echinococcus granulosus | histone deacetylase 1 | 0.029 | 0.3677 | 0.3663 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0062 | 0.0486 | 0.0466 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0901 | 0.0882 |
Brugia malayi | Kelch motif family protein | 0.0057 | 0.0421 | 0.0401 |
Wolbachia endosymbiont of Brugia malayi | isocitrate dehydrogenase | 0.009 | 0.0885 | 0.5 |
Loa Loa (eye worm) | isocitrate dehydrogenase gamma subunit | 0.009 | 0.0885 | 0.0872 |
Echinococcus granulosus | calpain | 0.0087 | 0.0835 | 0.0816 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.029 | 0.3677 | 0.3613 |
Schistosoma mansoni | glutamate receptor kainate | 0.0149 | 0.1706 | 0.1689 |
Leishmania major | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4647 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0158 | 0.1833 | 0.1816 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0055 | 0.0395 | 0.0395 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0062 | 0.0486 | 0.2567 |
Schistosoma mansoni | isocitrate dehydrogenase | 0.009 | 0.0885 | 0.0866 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0116 | 0.0095 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.0055 | 0.0395 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0116 | 0.0095 |
Echinococcus multilocularis | histone deacetylase | 0.0362 | 0.4686 | 0.4686 |
Echinococcus multilocularis | gamma secretase subunit aph 1 | 0.0237 | 0.2944 | 0.2944 |
Trypanosoma brucei | histone deacetylase 3 | 0.0362 | 0.4686 | 0.4633 |
Chlamydia trachomatis | pyruvate kinase | 0.0034 | 0.01 | 0.5 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0116 | 0.0016 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0116 | 0.0042 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0021 | 0.0021 |
Trypanosoma brucei | calpain-like protein, putative | 0.0087 | 0.0835 | 0.0743 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.01 | 0.0079 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0742 | 1 | 1 |
Trypanosoma brucei | kinesin, putative | 0.0061 | 0.0471 | 0.0375 |
Brugia malayi | hypothetical protein | 0.0062 | 0.0486 | 0.0466 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0742 | 1 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.023 | 0.2834 | 0.2819 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.029 | 0.3677 | 0.3663 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0742 | 1 | 1 |
Brugia malayi | calpain 7 | 0.0087 | 0.0835 | 0.0816 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.029 | 0.3677 | 0.363 |
Plasmodium vivax | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4633 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0032 | 0.0074 | 0.006 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0032 | 0.0074 | 0.0053 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0116 | 0.0042 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0116 | 0.0016 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0021 | 0.0007 |
Echinococcus granulosus | histone deacetylase 6 | 0.0368 | 0.477 | 0.4759 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4647 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0034 | 0.01 | 0.0079 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.008 | 0.0748 | 0.0748 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0116 | 0.0043 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0116 | 0.0043 |
Echinococcus granulosus | calpain 7 C02 family | 0.0087 | 0.0835 | 0.0816 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0362 | 0.4686 | 0.4675 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.01 | 0.0027 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2156 |
Loa Loa (eye worm) | integrin beta-2 | 0.0363 | 0.4696 | 0.4689 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0149 | 0.1706 | 0.1689 |
Loa Loa (eye worm) | calpain | 0.0087 | 0.0835 | 0.0823 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0032 | 0.0074 | 0.006 |
Brugia malayi | Histone deacetylase 1 | 0.029 | 0.3677 | 0.3663 |
Onchocerca volvulus | 0.0081 | 0.0756 | 0.4058 | |
Echinococcus multilocularis | integrin beta 2 | 0.0266 | 0.3338 | 0.3338 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0158 | 0.1833 | 0.1772 |
Onchocerca volvulus | 0.0032 | 0.0074 | 0.0292 | |
Mycobacterium ulcerans | 3-isopropylmalate dehydrogenase | 0.009 | 0.0885 | 1 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0032 | 0.0074 | 0.006 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.029 | 0.3677 | 0.3613 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0421 | 0.5515 | 0.5506 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0032 | 0.0074 | 0.006 |
Toxoplasma gondii | cathepsin B | 0.0095 | 0.0959 | 0.0868 |
Onchocerca volvulus | 0.0035 | 0.0116 | 0.0523 | |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.247 | 0.246 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0074 | 0.0053 |
Echinococcus granulosus | tyrosine kinase | 0.0032 | 0.0074 | 0.0053 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Schistosoma mansoni | calpain C (C02 family) | 0.0087 | 0.0835 | 0.0816 |
Echinococcus granulosus | integrin beta 2 | 0.0266 | 0.3338 | 0.3324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0901 | 0.0882 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0901 | 0.0901 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0116 | 0.0016 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Echinococcus granulosus | calpain 5 | 0.0087 | 0.0835 | 0.0816 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0116 | 0.0043 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.029 | 0.3677 | 0.3613 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.029 | 0.3677 | 0.3663 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0756 | 0.0743 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0021 | 0.0021 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0742 | 1 | 1 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0057 | 0.0421 | 0.0408 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0169 | 0.1988 | 0.1988 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0081 | 0.0756 | 0.0737 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0095 | 0.0959 | 0.094 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0032 | 0.0074 | 0.0074 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0289 | 0.3669 | 0.3656 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.01 | 0.0079 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0087 | 0.0835 | 0.0816 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0034 | 0.01 | 0.0079 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0057 | 0.0037 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0116 | 0.0102 |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.0237 | 0.2944 | 0.2934 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0116 | 0.0016 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0116 | 0.0095 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0116 | 0.0198 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0362 | 0.4686 | 0.4686 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0158 | 0.1833 | 0.175 |
Echinococcus granulosus | glutamate receptor 2 | 0.0181 | 0.2156 | 0.2139 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0055 | 0.0395 | 0.0395 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0032 | 0.0074 | 0.0053 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2139 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0167 | 0.0154 |
Trypanosoma brucei | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4633 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0055 | 0.0395 | 0.0375 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0901 | 0.0882 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.0055 | 0.0395 | 0.0395 |
Brugia malayi | Cell death protein 3 precursor | 0.0062 | 0.0486 | 0.0466 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0116 | 0.0016 |
Brugia malayi | calpain family protein 1 | 0.023 | 0.2834 | 0.2819 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0032 | 0.0074 | 0.0292 |
Echinococcus granulosus | histone deacetylase 8 | 0.0158 | 0.1833 | 0.1816 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0057 | 0.0037 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0116 | 0.0095 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0272 | 0.3433 | 0.3433 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.01 | 0.01 |
Schistosoma mansoni | histone deacetylase | 0.029 | 0.3677 | 0.3663 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.029 | 0.3677 | 0.3668 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0486 | 0.0473 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0057 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0095 | 0.0959 | 0.0892 |
Brugia malayi | calpain family protein 1 | 0.023 | 0.2834 | 0.2819 |
Schistosoma mansoni | unc-13 (munc13) | 0.009 | 0.0885 | 0.0866 |
Plasmodium falciparum | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4633 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0037 | 0.0147 | 0.0126 |
Onchocerca volvulus | 0.0143 | 0.1624 | 0.8846 | |
Giardia lamblia | Cathepsin B precursor | 0.0095 | 0.0959 | 0.2402 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0021 | 0.0021 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.029 | 0.3677 | 1 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0055 | 0.0395 | 0.0375 |
Schistosoma mansoni | tyrosine kinase | 0.0032 | 0.0074 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.1624 | 0.1612 |
Trichomonas vaginalis | histone deacetylase, putative | 0.029 | 0.3677 | 1 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0048 | 0.0301 | 0.028 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0116 | 0.0016 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0081 | 0.0756 | 0.0737 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0362 | 0.4686 | 0.4647 |
Echinococcus granulosus | cathepsin b | 0.0289 | 0.3669 | 0.3656 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.01 | 0.0027 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0081 | 0.0756 | 0.0737 |
Schistosoma mansoni | glutamate receptor kainate | 0.0149 | 0.1706 | 0.1689 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0742 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0767 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0079 | 0.073 | 0.071 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0742 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0116 | 0.0102 |
Onchocerca volvulus | Deterin homolog | 0.0081 | 0.0756 | 0.4058 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0116 | 0.0016 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.029 | 0.3677 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0021 | 0.0007 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0158 | 0.1833 | 0.1816 |
Entamoeba histolytica | protein kinase, putative | 0.0061 | 0.0471 | 0.1104 |
Echinococcus multilocularis | histone deacetylase 3 | 0.029 | 0.3677 | 0.3677 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.024 | 0.298 | 0.2965 |
Trypanosoma brucei | histone deacetylase 1 | 0.029 | 0.3677 | 0.3613 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0063 | 0.0503 | 0.0483 |
Trypanosoma cruzi | kinesin, putative | 0.0061 | 0.0471 | 0.0401 |
Echinococcus granulosus | cathepsin b | 0.0289 | 0.3669 | 0.3656 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0116 | 0.0016 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0289 | 0.3669 | 0.3622 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0362 | 0.4686 | 0.4686 |
Echinococcus multilocularis | NMDA receptor | 0.0055 | 0.0395 | 0.0395 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0158 | 0.1833 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0901 | 0.0882 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0486 | 0.0466 |
Trichomonas vaginalis | isocitrate dehydrogenase, putative | 0.009 | 0.0885 | 0.2194 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Echinococcus granulosus | caspase 2 | 0.0062 | 0.0486 | 0.0466 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0149 | 0.1706 | 0.1689 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0326 | 0.4182 | 0.4123 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0063 | 0.0503 | 0.0483 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0742 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.2834 | 0.2825 |
Trypanosoma brucei | calpain-like protein, putative | 0.0087 | 0.0835 | 0.0743 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0116 | 0.0042 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0149 | 0.1706 | 0.1695 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0266 | 0.3347 | 0.3347 |
Onchocerca volvulus | 0.0062 | 0.0486 | 0.2567 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2156 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0074 | 0.006 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0181 | 0.2156 | 0.2156 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0116 | 0.0016 |
Echinococcus multilocularis | calpain | 0.0087 | 0.0835 | 0.0835 |
Echinococcus granulosus | histone deacetylase | 0.0362 | 0.4686 | 0.4675 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0062 | 0.0486 | 0.0486 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0181 | 0.2156 | 0.2156 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0087 | 0.0835 | 0.0743 |
Echinococcus multilocularis | histone deacetylase 1 | 0.029 | 0.3677 | 0.3677 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 69 uM | Inhibition of Hepatitis C virus NS3 serine protease | ChEMBL. | 15501035 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.