Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.1289 | 0.4186 | 0.4157 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0072 | 0.0059 |
Echinococcus multilocularis | serotonin receptor | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0072 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.1289 | 0.4186 | 1 |
Mycobacterium ulcerans | secreted Mpt51/Mpb51 antigen protein FbpD | 0.0039 | 0.0072 | 0.0059 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0034 | 0.0054 | 0.013 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | larval opioid receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | amine GPCR | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | G-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | esterase D | 0.0039 | 0.0072 | 0.0172 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.1289 | 0.4186 | 0.4157 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.1289 | 0.4186 | 0.4157 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | RE15519p | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | somatostatin receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.1289 | 0.4186 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0146 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0137 | 0.0327 |
Schistosoma mansoni | adenoreceptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | neuropeptide receptor | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0072 | 0.0059 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0146 | 0.0097 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Brugia malayi | putative neuropeptide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.1289 | 0.4186 | 1 |
Mycobacterium leprae | SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) | 0.0924 | 0.2985 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | myosin xvIII | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0034 | 0.0054 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0034 | 0.0054 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.1289 | 0.4186 | 0.4157 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | neuropeptide F receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Brugia malayi | GnHR receptor homolog | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0059 | 0.0137 | 0.021 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.1289 | 0.4186 | 1 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0048 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Entamoeba histolytica | endo-1,4-beta-xylanase, putative | 0.0039 | 0.0072 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0146 | 0.0233 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0146 | 0.0097 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0146 | 0.0349 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Echinococcus granulosus | serotonin receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.1289 | 0.4186 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.1289 | 0.4186 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0034 | 0.0054 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | sex peptide receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0146 | 0.0097 |
Echinococcus multilocularis | neuropeptide receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0146 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Plasmodium falciparum | plasmepsin VI | 0.0059 | 0.0137 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0146 | 0.0349 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | neuropeptide Y receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0174 | 0.0515 | 0.0468 |
Plasmodium falciparum | plasmepsin II | 0.0059 | 0.0137 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0059 | 0.0137 | 0.0087 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.1289 | 0.4186 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | neuropeptide s receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0556 | 0.1771 | 0.173 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | neuropeptide F receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | serotonin receptor | 0.1289 | 0.4186 | 1 |
Plasmodium vivax | plasmepsin IV, putative | 0.0059 | 0.0137 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0059 | 0.0137 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0034 | 0.0054 | 0.013 |
Brugia malayi | Dopamine receptor | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | amine GPCR | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Plasmodium falciparum | plasmepsin IV | 0.0059 | 0.0137 | 0.5 |
Echinococcus granulosus | g-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0059 | 0.0137 | 0.5 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0059 | 0.0137 | 0.021 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.1289 | 0.4186 | 1 |
Brugia malayi | Serotonin receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Echinococcus multilocularis | fmrfamide receptor | 0.1289 | 0.4186 | 1 |
Plasmodium falciparum | plasmepsin I | 0.0059 | 0.0137 | 0.5 |
Mycobacterium ulcerans | secreted antigen 85-A FbpA | 0.0039 | 0.0072 | 0.0059 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Brugia malayi | Esterase D | 0.0039 | 0.0072 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0146 | 0.0233 |
Schistosoma mansoni | biogenic amine receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0146 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0146 | 0.0349 |
Echinococcus multilocularis | sex peptide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.1289 | 0.4186 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0034 | 0.0054 | 0.5 |
Brugia malayi | AKH receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.1289 | 0.4186 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.005 | 0.0119 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0146 | 0.0097 |
Echinococcus granulosus | neuropeptides capa receptor | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0059 | 0.0137 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.1289 | 0.4186 | 1 |
Brugia malayi | G-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.1289 | 0.4186 | 0.4157 |
Brugia malayi | Cytochrome P450 family protein | 0.0034 | 0.0054 | 0.013 |
Brugia malayi | G protein-coupled receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.005 | 0.0119 |
Echinococcus granulosus | S formylglutathione hydrolase | 0.0039 | 0.0072 | 0.0053 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1289 | 0.4186 | 0.4157 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.005 | 0.0119 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | 0.1289 | 0.4186 | 1 | |
Mycobacterium ulcerans | secreted antigen 85-C FbpC | 0.0924 | 0.2985 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0072 | 0.0059 |
Schistosoma mansoni | opsin-like receptor | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0174 | 0.0515 | 0.0468 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.1289 | 0.4186 | 0.4157 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Brugia malayi | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.1289 | 0.4186 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.1289 | 0.4186 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.1289 | 0.4186 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | amine GPCR | 0.1289 | 0.4186 | 0.4157 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | Serotonin receptor | 0.1289 | 0.4186 | 1 |
Mycobacterium tuberculosis | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) | 0.0924 | 0.2985 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.1289 | 0.4186 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0146 | 0.0349 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.1289 | 0.4186 | 0.4157 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0059 | 0.0137 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | S formylglutathione hydrolase | 0.0039 | 0.0072 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | amine GPCR | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | g-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.1289 | 0.4186 | 1 |
Mycobacterium ulcerans | secreted antigen 85-B FbpB | 0.0039 | 0.0072 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.005 | 0.0119 |
Echinococcus granulosus | neuropeptides capa receptor | 0.1289 | 0.4186 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0034 | 0.0054 | 0.013 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.1289 | 0.4186 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.1289 | 0.4186 | 0.4157 |
Echinococcus granulosus | allatostatin A receptor | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.1289 | 0.4186 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.1289 | 0.4186 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.1289 | 0.4186 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0034 | 0.0054 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.005 | 0.0119 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0059 | 0.0137 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.1289 | 0.4186 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.1289 | 0.4186 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 4.95 uM | Protease inhibitory activity of the compound against HIV-1 r13363 mutant strain was determined | ChEMBL. | 15771440 |
EC50 (functional) | = 5.75 uM | Protease inhibitory activity of the compound against HIV-1 GSS004421 mutant strain was determined | ChEMBL. | 15771440 |
EC50 (functional) | = 6.01 uM | Protease inhibitory activity of the compound against HIV-1 r13034 mutant strain was determined | ChEMBL. | 15771440 |
EC50 (functional) | = 6.43 uM | Protease inhibitory activity of the compound against HIV-1 r13025 mutant strain was determined | ChEMBL. | 15771440 |
EC50 (functional) | = 7.36 uM | Protease inhibitory activity of the compound against wild type HIV-1 IIIB was determined | ChEMBL. | 15771440 |
IC50 (functional) | = 150 nM | Inhibitory concentration for antiviral inhibition against HIV-1 in MT-4 cell culture | ChEMBL. | 15975788 |
IC50 (functional) | = 440 nM | Inhibitory concentration against multi-PI resistant EP13 in MT-4 cell lines(fold range = 3) | ChEMBL. | 15975788 |
IC50 (functional) | > 1000 nM | Inhibitory concentration against multi-PI resistant D545701 in MT-4 cell lines(fold range > 7) | ChEMBL. | 15975788 |
Ki (binding) | = 0.04 nM | Inhibition constant against HIV-1 protease | ChEMBL. | 15975788 |
pCC50 (functional) | < 4.49 uM | Toxicity value of the compound against wild type HIV-1 IIIB was determined | ChEMBL. | 15771440 |
Potency (functional) | 26.8325 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.