Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0054 | 1 | 1 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0054 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0039 | 0.5433 | 1 |
Brugia malayi | Cation transporter family protein | 0.0036 | 0.4697 | 0.4697 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0036 | 0.4697 | 0.4697 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0039 | 0.5433 | 0.5433 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0039 | 0.5433 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.4697 | 0.4697 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0054 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0034 | 0.4048 | 0.4048 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0054 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | glutamate receptor 2 | 0.0034 | 0.4048 | 0.4048 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.3953 | 0.3953 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | glutamate receptor kainate | 0.0054 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | nuclear hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | FTZ F1 alpha | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | glutamate receptor kainate | 0.0054 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0054 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | glutamate receptor kainate | 0.0054 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0039 | 0.5433 | 0.5433 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0039 | 0.5433 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0054 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0054 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.4697 | 0.4697 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0036 | 0.4697 | 0.4697 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | coup transcription factor | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | steroid hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | glutamate receptor 2 | 0.0054 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0039 | 0.5433 | 0.5433 |
Onchocerca volvulus | 0.0039 | 0.5433 | 1 | |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0054 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0054 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0054 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | nuclear receptor NHR-88 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | ecdysteroid receptor | 0.0039 | 0.5433 | 0.5433 |
Schistosoma mansoni | thyroid hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0039 | 0.5433 | 0.5433 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0054 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0054 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0039 | 0.5433 | 0.5433 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0039 | 0.5433 | 0.5433 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0054 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.