Detailed information for compound 330764

Basic information

Technical information
  • TDR Targets ID: 330764
  • Name: (2S)-N-[(2S)-1-[[(2S)-1-(2-chloro-4-nitroanil ino)-1-oxo-3-phenylpropan-2-yl]amino]-3-hydro xy-1-oxobutan-2-yl]-4-methyl-2-[[(2S)-3-methy l-2-(propanoylamino)butanoyl]amino]pentanamid e
  • MW: 689.199 | Formula: C33H45ClN6O8
  • H donors: 6 H acceptors: 8 LogP: 4.27 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)Nc1ccc(cc1Cl)[N+](=O)[O-])Cc1ccccc1)C(O)C)CC(C)C)C(C)C
  • InChi: 1S/C33H45ClN6O8/c1-7-27(42)38-28(19(4)5)32(45)36-25(15-18(2)3)31(44)39-29(20(6)41)33(46)37-26(16-21-11-9-8-10-12-21)30(43)35-24-14-13-22(40(47)48)17-23(24)34/h8-14,17-20,25-26,28-29,41H,7,15-16H2,1-6H3,(H,35,43)(H,36,45)(H,37,46)(H,38,42)(H,39,44)/t20?,25-,26-,28-,29-/m0/s1
  • InChiKey: DHJAWPMDJISKEQ-HNLCQUMASA-N  

Network

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Synonyms

  • (2S)-N-[(1S)-1-[[(1S)-1-benzyl-2-(2-chloro-4-nitro-anilino)-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]-4-methyl-2-[[(2S)-3-methyl-2-(propanoylamino)butanoyl]amino]pentanamide
  • (2S)-N-[(1S)-1-[[[(1S)-1-benzyl-2-(2-chloro-4-nitroanilino)-2-oxoethyl]amino]-oxomethyl]-2-hydroxypropyl]-4-methyl-2-[[(2S)-3-methyl-1-oxo-2-(1-oxopropylamino)butyl]amino]pentanamide
  • (2S)-N-[(2S)-1-[[(2S)-1-[(2-chloro-4-nitro-phenyl)amino]-1-oxo-3-phenyl-propan-2-yl]amino]-3-hydroxy-1-oxo-butan-2-yl]-4-methyl-2-[[(2S)-3-methyl-2-(propanoylamino)butanoyl]amino]pentanamide
  • (2S)-N-[(1S)-1-[[(1S)-1-benzyl-2-(2-chloro-4-nitro-anilino)-2-keto-ethyl]carbamoyl]-2-hydroxy-propyl]-4-methyl-2-[[(2S)-3-methyl-2-propionamido-butanoyl]amino]valeramide
  • (2S)-N-[(2S)-1-[[(2S)-1-[(2-chloro-4-nitrophenyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-4-methyl-2-[[(2S)-3-methyl-2-(propanoylamino)butanoyl]amino]pentanamide
  • (2S)-N-[(1S)-1-[[(1S)-2-[(2-chloro-4-nitro-phenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]carbamoyl]-2-hydroxy-propyl]-4-methyl-2-[[(2S)-3-methyl-2-(propanoylamino)butanoyl]amino]pentanamide
  • (2S)-N-[(1S)-1-[[[(1S)-2-[(2-chloro-4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-oxomethyl]-2-hydroxypropyl]-4-methyl-2-[[(2S)-3-methyl-1-oxo-2-(1-oxopropylamino)butyl]amino]pentanamide
  • (2S)-N-[(1S)-1-[[(1S)-1-(benzyl)-2-[(2-chloro-4-nitro-phenyl)amino]-2-keto-ethyl]carbamoyl]-2-hydroxy-propyl]-4-methyl-2-[[(2S)-3-methyl-2-propionamido-butanoyl]amino]valeramide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii histone deacetylase HDAC5 0.0417 0.0866 0.0866
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0107 0.0499
Plasmodium falciparum DNA repair protein REV1, putative 0.0027 0.0029 0.0029
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0271 0.1261
Loa Loa (eye worm) hypothetical protein 0.0106 0.0199 0.0926
Schistosoma mansoni protein kinase subunit beta 0.011 0.0206 0.0684
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.0047 0.0217
Loa Loa (eye worm) AUR protein kinase 0.0167 0.033 0.1538
Brugia malayi TAR-binding protein 0.0064 0.0107 0.0497
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0014 0.0045
Toxoplasma gondii zinc finger cdgsh type protein 0.0014 0.0001 0.0001
Brugia malayi steroid hormone receptor 0.0051 0.008 0.0372
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0021 0.0016 0.0016
Mycobacterium ulcerans glutaminase 0.0282 0.0576 0.0565
Schistosoma mansoni zinc finger protein 0.0024 0.0022 0.0073
Trypanosoma brucei GMP reductase 0.002 0.0014 0.0065
Schistosoma mansoni roundabout 0.0022 0.0018 0.0059
Schistosoma mansoni hypothetical protein 0.0686 0.1446 0.4789
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0018 0.0009 0.0086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0108 0.0356
Mycobacterium ulcerans hypothetical protein 0.002 0.0014 0.0002
Entamoeba histolytica protein kinase, putative 0.0187 0.0372 0.2102
Giardia lamblia Hypothetical protein 0.002 0.0014 0.0012
Leishmania major histone deacetylase, putative 0.082 0.1733 0.8075
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0102 0.0189 0.0361
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0567 0.1189 0.3935
Plasmodium vivax histone deacetylase, putative 0.1012 0.2146 0.2146
Trypanosoma cruzi GMP reductase 0.002 0.0014 0.0065
Entamoeba histolytica hypothetical protein 0.0073 0.0127 0.0685
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0022 0.0103
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0047 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0107 0.0355
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0047 0.0215
Toxoplasma gondii IMP dehydrogenas 0.002 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0052 0.0245
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.005 0.0078 0.0362
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0012 0.0055
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0047 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.008 0.0372
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0605 0.2819
Echinococcus granulosus histone deacetylase 0.1012 0.2146 0.7106
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0047 0.0218
Entamoeba histolytica recQ family helicase, putative 0.002 0.0014 0.0028
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0211 0.1171
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.005 0.0078 0.013
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0059 0.0058
Onchocerca volvulus 0.0149 0.029 0.2856
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0045 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0132
Treponema pallidum DNA ligase (lig) 0.005 0.0078 0.0991
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.082 0.1733 1
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0544 0.114 0.2301
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.002 0.0014 0.0004
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0026 0.0026
Brugia malayi CXXC zinc finger family protein 0.0057 0.0094 0.0434
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0072 0.0337
Loa Loa (eye worm) hypothetical protein 0.0253 0.0515 0.2399
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0271 0.0895
Echinococcus granulosus tar DNA binding protein 0.0064 0.0107 0.0353
Loa Loa (eye worm) Smad1 0.0025 0.0023 0.0108
Echinococcus granulosus microtubule associated protein 2 0.1418 0.302 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0142 0.047
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0052 0.0231
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0023
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0048 0.0158
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0498 0.2835
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.008 0.0091
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.008 0.0266
Entamoeba histolytica deoxycytidyl transferase, putative 0.0089 0.0161 0.0877
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0142 0.0162
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0029 0.0136
Echinococcus multilocularis titin 0.0016 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0187 0.0372 0.1229
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.002 0.0014 0.0015
Leishmania major serine/threonine-protein kinase, putative 0.0021 0.0016 0.0075
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0234 0.0474 0.2206
Schistosoma mansoni hypothetical protein 0.008 0.0142 0.0472
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Schistosoma mansoni importin beta-1 0.003 0.0034 0.0111
Mycobacterium ulcerans DNA polymerase IV 0.0142 0.0275 0.0264
Schistosoma mansoni ap endonuclease 0.0019 0.0012 0.0039
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.01 0.0114
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0226 0.0457 0.2586
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0014 0.0063
Schistosoma mansoni topbp1 0.005 0.0078 0.0257
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0016 0.0038
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0021 0.0016 0.0016
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0018 0.0009 0.0043
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.005 0.0078 0.0359
Trypanosoma brucei histone deacetylase, putative 0.1012 0.2146 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0047 0.0218
Echinococcus multilocularis histone deacetylase 8 0.0417 0.0866 0.099
Plasmodium falciparum NIMA related kinase 2 0.0021 0.0016 0.0016
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.026 0.0528 0.2462
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0035 0.0021
Loa Loa (eye worm) histone deacetylase 0.1012 0.2146 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.008 0.0264
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0235 0.0777
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0605 0.2819
Brugia malayi Niemann-Pick C1 protein precursor 0.0202 0.0405 0.1886
Giardia lamblia Kinase, NEK 0.0021 0.0016 0.0025
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0005 0.0014
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0007 0.0007
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0021 0.0016 0.0075
Trypanosoma brucei DNA polymerase IV, putative 0.0142 0.0275 0.1282
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0128
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.002 0.0014 0.0004
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0047 0.0218
Schistosoma mansoni hypothetical protein 0.008 0.0142 0.0472
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0339 0.07 0.326
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0119
Schistosoma mansoni protein kinase 0.0167 0.033 0.1093
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0072 0.024
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0028 0.0092
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0017 0.0078
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.008 0.0264
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.002 0.0014 0.0004
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0168 0.0331 0.0378
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0235 0.0475 0.1572
Leishmania major hypothetical protein, conserved 0.0016 0.0005 0.0023
Brugia malayi hypothetical protein 0.0027 0.0028 0.0129
Echinococcus granulosus importin subunit beta 1 0.003 0.0034 0.011
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0014 0.0045
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0011 0.0034
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.005 0.0078 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0073 0.0242
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0072 0.0337
Echinococcus multilocularis protein patched 0.0087 0.0157 0.0179
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.008 0.0785
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0017 0.0078
Schistosoma mansoni histone deacetylase 1 2 3 0.0417 0.0866 0.2868
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0231 0.1075
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0021 0.0016 0.0052
Trichomonas vaginalis ran, putative 0.0022 0.0017 0.0044
Plasmodium vivax SET domain protein, putative 0.0032 0.0039 0.0038
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0059 0.0274
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0012 0.0015
Echinococcus multilocularis BRCA1 associated protein 0.0018 0.0009 0.001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0065 0.0321
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0041 0.0059 0.0058
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0026 0.0025
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0016 0.0074
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0027 0.0126
Brugia malayi Protein kinase domain containing protein 0.0187 0.0372 0.173
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0041 0.0059 0.0047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0182
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.23 0.4916 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0362 0.0749 0.349
Brugia malayi serine/threonine-protein kinase 6 0.0167 0.033 0.1536
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0253 0.0515 0.2399
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.002 0.0014 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.008 0.0374
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.024
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0014 0.0013
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.002 0.0014 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.1012 0.2146 1
Brugia malayi Pax transcription activation domain interacting protein 0.005 0.0078 0.0359
Onchocerca volvulus 0.0245 0.0498 0.4901
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0018 0.0059
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0167 0.033 0.1862
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0018 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0005 0.0016
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0029 0.0136
Echinococcus granulosus histone deacetylase 6 0.1012 0.2146 0.7106
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.008 0.0372
Schistosoma mansoni alkaline phosphatase 0.0168 0.0331 0.1095
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0073 0.0073
Brugia malayi serine/threonine protein kinase 6 0.0167 0.033 0.1536
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0142 0.047
Schistosoma mansoni hypothetical protein 0.0084 0.015 0.0497
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0048 0.022
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0022 0.01
Brugia malayi histone deacetylase 11 0.0417 0.0866 0.4035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Leishmania major hypothetical protein, conserved 0.0018 0.0009 0.0043
Plasmodium falciparum histone deacetylase, putative 0.1012 0.2146 0.2146
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0023 0.0077
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0089 0.0161 0.0748
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0005 0.0005
Toxoplasma gondii CBS family protein 0.002 0.0014 0.0014
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0047 0.0071
Brugia malayi SWIRM domain containing protein 0.0041 0.0059 0.0271
Schistosoma mansoni DNA polymerase IV / kappa 0.0027 0.0029 0.0097
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0605 0.2819
Brugia malayi tailless protein 0.0024 0.0022 0.01
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0016 0.0018
Schistosoma mansoni chromosome transmission fidelity factor 0.005 0.0078 0.0257
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0073 0.0356
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0107 0.0122
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.011 0.0206 0.0962
Schistosoma mansoni septate junction protein 0.0022 0.0018 0.0059
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0014 0.0014
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0022 0.0073
Trypanosoma cruzi histone deacetylase, putative 0.0417 0.0866 0.4036
Loa Loa (eye worm) hypothetical protein 0.0149 0.029 0.1353
Trichomonas vaginalis rotamase, putative 0.0066 0.0113 0.0601
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Schistosoma mansoni vesicular amine transporter 0.0036 0.0048 0.0158
Loa Loa (eye worm) hypothetical protein 0.0431 0.0896 0.4175
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.0018 0.002
Entamoeba histolytica hypothetical protein 0.0073 0.0127 0.0685
Loa Loa (eye worm) oxidoreductase 0.0036 0.0047 0.0218
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0047 0.0218
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0231 0.022
Brugia malayi Peroxidasin 0.0022 0.0018 0.0081
Loa Loa (eye worm) glutaminase 0.0282 0.0576 0.2685
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.008 0.0372
Loa Loa (eye worm) hypothetical protein 0.0156 0.0305 0.1422
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0016 0.0071
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0127 0.0421
Toxoplasma gondii NEK kinase 0.0021 0.0016 0.0016
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0016 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Trypanosoma brucei histone deacetylase 4 0.1012 0.2146 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0157 0.0731
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0065 0.0109 0.0581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0343 0.1594
Echinococcus multilocularis lachesin 0.0022 0.0018 0.002
Trypanosoma cruzi histone deacetylase, putative 0.1012 0.2146 1
Trypanosoma brucei unspecified product 0.0061 0.0101 0.0473
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0022 0.0025
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0107 0.0499
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0079 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0079 0.0368
Echinococcus granulosus BRCA1 associated protein 0.0018 0.0009 0.0029
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0018 0.0009 0.0043
Trypanosoma brucei aurora B kinase 0.0167 0.033 0.1538
Giardia lamblia Aurora kinase 0.0167 0.033 0.185
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0187 0.0372 0.1732
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0089 0.0161 0.053
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0036 0.0047 0.0035
Schistosoma mansoni brca1-associated protein (brap2) 0.0018 0.0009 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0026 0.0025
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0023
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0035 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.0016 0.004
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0124 0.0236 0.0782
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.002 0.0014 0.0015
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.002 0.0014 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Brugia malayi ancient conserved domain protein 4 0.002 0.0014 0.0062
Echinococcus multilocularis histone deacetylase 6 0.1012 0.2146 0.2455
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.013 0.0605
Trichomonas vaginalis AGC family protein kinase 0.0167 0.033 0.1862
Plasmodium falciparum protein kinase 5 0.0048 0.0072 0.0072
Schistosoma mansoni histone deacetylase hda2 0.103 0.2185 0.7236
Echinococcus multilocularis dna polymerase kappa 0.0142 0.0275 0.0314
Echinococcus multilocularis histone deacetylase 3 0.082 0.1733 0.1982
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.002 0.0014 0.0065
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0016 0.0074
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0005 0.0016
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0005 0.0016
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0089 0.0161 0.0183
Entamoeba histolytica Ran family GTPase 0.0022 0.0017 0.0044
Trichomonas vaginalis replication factor C large subunit, putative 0.005 0.0078 0.0397
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0039 0.0039
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0052 0.024
Trichomonas vaginalis DNA polymerase eta, putative 0.0142 0.0275 0.1542
Brugia malayi hypothetical protein 0.0024 0.0022 0.01
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.008 0.0266
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0079 0.0078
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Plasmodium falciparum serine/threonine protein kinase, putative 0.0167 0.033 0.033
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0154 0.0714
Entamoeba histolytica protein kinase, putative 0.0187 0.0372 0.2102
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0036 0.0047 0.0035
Echinococcus multilocularis snurportin 1 0.0315 0.0648 0.0741
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0016 0.0053
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0059 0.0277
Giardia lamblia Replication factor C, subunit 1 0.005 0.0078 0.0383
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0059 0.0097 0.0319
Giardia lamblia DNA damage repair protein 0.0027 0.0029 0.0101
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0291 0.1356
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0211 0.0699
Echinococcus granulosus sterol regulatory element binding protein 0.0087 0.0157 0.0518
Loa Loa (eye worm) hypothetical protein 0.0058 0.0096 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0144 0.067
Echinococcus granulosus expressed conserved protein 0.019 0.0379 0.1253
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Echinococcus multilocularis neuroglian 0.0022 0.0018 0.002
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0521 0.109 0.5078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0016 0.0038
Echinococcus granulosus FTZ F1 alpha 0.0051 0.008 0.0264
Echinococcus granulosus replication factor c subunit 1 0.005 0.0078 0.0255
Echinococcus granulosus histone deacetylase 6 0.103 0.2185 0.7236
Echinococcus granulosus nibrin 0.005 0.0078 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.008 0.0372
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0014 0.0065
Schistosoma mansoni hypothetical protein 0.0085 0.0154 0.0509
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0021 0.0016 0.0074
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.002 0.0014 0.0002
Brugia malayi Smad1 0.0025 0.0023 0.0105
Schistosoma mansoni topbp1 0.005 0.0078 0.0257
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0065 0.0064
Brugia malayi amine oxidase, flavin-containing family protein 0.0041 0.0059 0.0271
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Leishmania major importin beta-1 subunit, putative 0.0024 0.0022 0.0101
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0072 0.0366
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0059 0.0058
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0072 0.0082
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0022 0.01
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0077
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0016 0.0015
Echinococcus multilocularis sterol regulatory element binding protein 0.0087 0.0157 0.0179
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.077
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.002 0.0013 0.0013
Onchocerca volvulus 0.0016 0.0005 0.0043
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.008 0.0264
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0052 0.0245
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0079 0.0403
Schistosoma mansoni cellular tumor antigen P53 0.0149 0.029 0.0962
Toxoplasma gondii histone deacetylase HDAC3 0.082 0.1733 0.1733
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0047 0.0218
Echinococcus granulosus lachesin 0.0022 0.0018 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Brugia malayi ImpB/MucB/SamB family protein 0.0089 0.0161 0.0746
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0014 0.0046
Wolbachia endosymbiont of Brugia malayi hemolysin 0.002 0.0014 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0079 0.0403
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.0016 0.004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Schistosoma mansoni cell adhesion molecule 0.0022 0.0018 0.0059
Brugia malayi hypothetical protein 0.0036 0.0048 0.022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0047 0.0215
Schistosoma mansoni chloride channel protein 0.002 0.0014 0.0046
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0072 0.0072
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0035 0.0021
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0079 0.0261
Echinococcus granulosus histone deacetylase 8 0.0417 0.0866 0.2867
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.002 0.0014 0.0015
Echinococcus granulosus roundabout 2 0.0022 0.0018 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0157 0.0856
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0057 0.0261
Toxoplasma gondii CBS domain-containing protein 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0157
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0072 0.0238
Echinococcus multilocularis neuroglian 0.0048 0.0073 0.0083
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0047 0.0071
Toxoplasma gondii histone deacetylase HDAC4 0.0417 0.0866 0.0866
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0079 0.0367
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0014 0.0001 0.0001
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0035 0.0136
Echinococcus granulosus histone deacetylase 7 0.1012 0.2146 0.7106
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0231 0.022
Plasmodium vivax JmjC domain containing protein 0.0016 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.008 0.0372
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.005 0.0078 0.0397
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0022 0.0025
Plasmodium falciparum NIMA related kinase 4 0.0021 0.0016 0.0016
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0014 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0012 0.0013
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0016 0.0038
Brugia malayi CLC chloride channel protein 0.002 0.0014 0.0062
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0187 0.0372 0.1732
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0168 0.0331 0.0378
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0231 0.1075
Echinococcus granulosus bloom syndrome protein 0.002 0.0014 0.0045
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0014 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0108 0.0501
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0167 0.033 0.033
Brugia malayi Flap endonuclease-1 0.0027 0.0027 0.0125
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0047 0.0047
Echinococcus granulosus protein kinase shaggy 0.0051 0.0079 0.0259
Schistosoma mansoni alkaline phosphatase 0.0168 0.0331 0.1095
Schistosoma mansoni tyrosine kinase 0.0027 0.0028 0.0093
Trypanosoma cruzi protein kinase, putative 0.0017 0.0007 0.0033
Echinococcus multilocularis aurora kinase A 0.0167 0.033 0.0377
Schistosoma mansoni hypothetical protein 0.0073 0.0127 0.0421
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0023 0.0075
Loa Loa (eye worm) hypothetical protein 0.0121 0.0231 0.1077
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Trypanosoma cruzi FHA domain containing protein, putative 0.005 0.0078 0.0362
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0072 0.0238
Schistosoma mansoni ran 0.0022 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0036 0.0047 0.0218
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.008 0.0372
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0241 0.0489 0.0972
Onchocerca volvulus 0.01 0.0185 0.1815
Echinococcus multilocularis roundabout 2 0.0022 0.0018 0.002
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0072 0.0238
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0003 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0022 0.01
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0036 0.0047 0.0035
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0059 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Onchocerca volvulus 0.005 0.0078 0.076
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0017 0.0078
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.008 0.0091
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0039 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0052 0.0058
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0018 0.0059
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0073 0.0356
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0378 0.0784 1
Echinococcus multilocularis histone deacetylase 6 0.1012 0.2146 0.2455
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0048 0.0054
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0029 0.0136
Loa Loa (eye worm) hypothetical protein 0.01 0.0185 0.0861
Brugia malayi 6-phosphofructokinase 0.0112 0.0211 0.0981
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0016 0.0051
Toxoplasma gondii chorismate synthase, putative 0.4663 1 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0231 0.022
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Brugia malayi glutaminase DH11.1 0.0282 0.0576 0.2683
Loa Loa (eye worm) hypothetical protein 0.0085 0.0154 0.0716
Brugia malayi cell division control protein 2 homolog 0.0048 0.0072 0.0335
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.005 0.0078 0.0362
Echinococcus multilocularis Smad4 0.0025 0.0023 0.0026
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.011 0.0206 0.0962
Loa Loa (eye worm) hypothetical protein 0.0202 0.0405 0.1888
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0072 0.0337
Mycobacterium ulcerans hypothetical protein 0.002 0.0014 0.0002
Echinococcus granulosus peroxidasin 0.0022 0.0018 0.0058
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0154 0.0175
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0012 0.0055
Mycobacterium ulcerans dehydrogenase 0.0041 0.0059 0.0047
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.011 0.0206 0.0962
Onchocerca volvulus 0.0024 0.0022 0.0212
Trypanosoma brucei NIMA-related protein kinase 0.0021 0.0016 0.0075
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.026 0.0528 0.0604
Schistosoma mansoni 3-dehydroquinate synthase 0.0241 0.0489 0.1618
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0026 0.0119
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0022 0.0071
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0072 0.0352
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0018 0.0009 0.0043
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0269 0.0524
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0282 0.0934
Brugia malayi hypothetical protein 0.0156 0.0305 0.142
Trypanosoma cruzi aurora B kinase, putative 0.0167 0.033 0.1538
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0017 0.0078
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0022 0.01
Loa Loa (eye worm) hypothetical protein 0.0046 0.007 0.0326
Entamoeba histolytica protein kinase domain containing protein 0.0167 0.033 0.1862
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0047 0.0217
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0167 0.033 0.0377
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0029 0.0136
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0048 0.0158
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0269 0.0519
Loa Loa (eye worm) hypothetical protein 0.0173 0.0343 0.1596
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0012 0.015
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0078 0.0397
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0016 0.0051
Schistosoma mansoni hypothetical protein 0.0173 0.0343 0.1134
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.008 0.0372
Echinococcus multilocularis roundabout 2 0.0022 0.0018 0.002
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.0581 0.3308
Brugia malayi MH2 domain containing protein 0.0362 0.0749 0.3488
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0035 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0071
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.002 0.0014 0.0044
Leishmania major hypothetical protein, conserved 0.011 0.0206 0.0962
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0052 0.0238
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.008 0.0091
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0047 0.0218
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.008 0.0264
Schistosoma mansoni histone deacetylase 4 5 0.1012 0.2146 0.7107
Plasmodium falciparum protoporphyrinogen oxidase 0.0041 0.0059 0.0058
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0047 0.0218
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0036 0.0047 0.0035
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0014 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0047 0.0215
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.002 0.0014 0.0004
Loa Loa (eye worm) hypothetical protein 0.082 0.1733 0.8075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.008 0.0372
Schistosoma mansoni cpg binding protein 0.0061 0.0101 0.0334
Onchocerca volvulus 0.0051 0.008 0.0785
Leishmania major hypothetical protein, conserved 0.0018 0.0009 0.0043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0011 0.0012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0089 0.0161 0.0303
Brugia malayi hypothetical protein 0.0026 0.0026 0.0117
Onchocerca volvulus 0.0121 0.0231 0.2272
Onchocerca volvulus 0.0036 0.0047 0.0455
Trypanosoma brucei histone deacetylase 3 0.1012 0.2146 1
Echinococcus multilocularis geminin 0.0686 0.1446 0.1654
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0154 0.0175
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0022 0.0071
Echinococcus multilocularis microtubule associated protein 2 0.1418 0.302 0.3454
Echinococcus granulosus titin 0.0016 0.0005 0.0014
Echinococcus multilocularis twitchin 0.0016 0.0005 0.0005
Brugia malayi Pre-SET motif family protein 0.0216 0.0434 0.2021
Leishmania major chloride channel protein, putative 0.002 0.0014 0.0065
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0127 0.0145
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0065 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Brugia malayi Histone deacetylase 1 0.082 0.1733 0.8074
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Onchocerca volvulus 0.047 0.098 0.9649
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0012 0.0011
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0017 0.0017
Brugia malayi Histone deacetylase family protein 0.1012 0.2146 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0605 0.2819
Echinococcus granulosus Immunoglobulin 0.0036 0.0048 0.0157
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0012 0.0055
Echinococcus granulosus H:Cl exchange transporter 7 0.002 0.0014 0.0044
Schistosoma mansoni histone deacetylase 0.082 0.1733 0.5738
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0047 0.0153
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0072 0.0337
Echinococcus multilocularis hemicentin 1 0.0022 0.0018 0.002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.008 0.0372
Schistosoma mansoni thyroid hormone receptor 0.0051 0.008 0.0266
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0231 0.1287
Loa Loa (eye worm) hypothetical protein 0.0307 0.063 0.2937
Brugia malayi Voltage gated chloride channel family protein 0.002 0.0014 0.0062
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.01 0.0331
Brugia malayi intracellular kinase 0.0051 0.0079 0.0364
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0021 0.0016 0.0075
Loa Loa (eye worm) hypothetical protein 0.0182 0.0362 0.1689
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0071
Loa Loa (eye worm) chloride channel 3 0.002 0.0014 0.0065
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0012 0.0038
Schistosoma mansoni hypothetical protein 0.0084 0.015 0.0497
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0017 0.0029
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.002 0.0013 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0078 0.0397
Plasmodium vivax histone deacetylase, putative 0.0417 0.0866 0.0866
Mycobacterium ulcerans hypothetical protein 0.0121 0.0231 0.022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.008 0.0372
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0211 0.0984
Plasmodium vivax protein kinase Crk2 0.0048 0.0072 0.0072
Echinococcus granulosus geminin 0.0686 0.1446 0.4788
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0072 0.0337
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0047 0.0218
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0047 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.008 0.0374
Brugia malayi ecdysone receptor 0.0024 0.0022 0.01
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0039 0.0127
Brugia malayi jmjC domain containing protein 0.0061 0.01 0.0466
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0271 0.0897
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0241 0.0489 0.0972
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0073 0.0341
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Plasmodium vivax importin-beta 2, putative 0.003 0.0034 0.0033
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0052 0.024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0107 0.0355
Onchocerca volvulus 0.0041 0.0059 0.0573
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0012 0.0011
Brugia malayi MH1 domain containing protein 0.0025 0.0023 0.0105
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0021 0.0016 0.0075
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0003 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0144 0.067
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0047 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0132
Mycobacterium ulcerans transcriptional regulator 0.002 0.0014 0.0002
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0016 0.0018
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0086 0.0399
Schistosoma mansoni hypothetical protein 0.0087 0.0157 0.0521
Leishmania major hypothetical protein, conserved 0.002 0.0014 0.0065
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.082 0.1733 1
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0059 0.0097 0.011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0028 0.0094
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0005 0.0016
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0023 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.008 0.0372
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0036 0.005
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.005 0.0078 0.0853
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0073 0.0341
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0073 0.037
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0211 0.0984
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Echinococcus granulosus H:Cl exchange transporter 3 0.002 0.0014 0.0044
Mycobacterium tuberculosis Conserved protein 0.002 0.0014 0.0004
Onchocerca volvulus 0.0431 0.0896 0.8822
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0241 0.0489 0.0477
Echinococcus multilocularis muscleblind protein 1 0.0307 0.063 0.072
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0072 0.0352
Leishmania major protein kinase, putative 0.0167 0.033 0.1538
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0052 0.0058
Brugia malayi hypothetical protein 0.0073 0.0127 0.0591
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0078 0.0397
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0079 0.0367
Trypanosoma cruzi histone deacetylase, putative 0.0417 0.0866 0.4036
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0022 0.0073
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0021 0.0016 0.0016
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Brugia malayi CHE-14 protein 0.0087 0.0157 0.0728
Onchocerca volvulus 0.002 0.0014 0.0132
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.026 0.0528 0.175
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0474 0.1569
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0029 0.0136
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0142 0.0664
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0155 0.0291
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0107 0.0355
Brugia malayi Pre-SET motif family protein 0.0032 0.0039 0.0179
Brugia malayi MH1 domain containing protein 0.0025 0.0023 0.0105
Echinococcus granulosus GPCR family 2 0.008 0.0142 0.047
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.002 0.0014 0.0028
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0027 0.0105
Brugia malayi 6-phosphofructokinase 0.0112 0.0211 0.0982
Echinococcus granulosus twitchin 0.0052 0.0083 0.0272
Plasmodium vivax histone deacetylase 1, putative 0.082 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.0431 0.0896 0.4175
Onchocerca volvulus 0.0036 0.0047 0.0455
Brugia malayi nuclear receptor NHR-67 0.0024 0.0022 0.01
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0035 0.015
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0054 0.0086 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0107 0.0355
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0021 0.0016 0.0052
Chlamydia trachomatis protoporphyrinogen oxidase 0.0041 0.0059 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0231 0.022
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0211 0.0984
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0187 0.0372 0.1732
Leishmania major DNA damage repair protein, putative 0.0027 0.0029 0.0136
Echinococcus granulosus flap endonuclease 1 0.0027 0.0027 0.0089
Entamoeba histolytica protein kinase, putative 0.0167 0.033 0.1862
Schistosoma mansoni cpg binding protein 0.0061 0.0101 0.0334
Onchocerca volvulus Histone deacetylase 10 homolog 0.0417 0.0866 0.8528
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0211 0.1171
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0013 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Echinococcus granulosus contactin 0.0022 0.0018 0.0058
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0211 0.0406
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0073 0.0242
Echinococcus multilocularis Protein lozenge 0.0054 0.0086 0.0098
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0012 0.0052
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0231 0.1287
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0231 0.0447
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0065
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0022 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Mycobacterium ulcerans hypothetical protein 0.0027 0.0029 0.0017
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0206 0.0413 0.0472
Brugia malayi MH2 domain containing protein 0.0025 0.0023 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0039 0.0129
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Echinococcus multilocularis peroxidasin 0.0022 0.0018 0.002
Schistosoma mansoni smad 0.0025 0.0023 0.0077
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0027 0.0027
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Echinococcus multilocularis protoporphyrinogen oxidase 0.0041 0.0059 0.0067
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0036 0.0047 0.0035
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0041 0.0059 0.0194
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.002 0.0014 0.0002
Entamoeba histolytica hypothetical protein 0.005 0.0078 0.0397
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0079 0.0089
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0271 0.1261
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0091 0.0165 0.0313
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0073 0.0341
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0078 0.0362
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.077
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0211 0.1171
Schistosoma mansoni DNA helicase recq5 0.002 0.0014 0.0046
Entamoeba histolytica protein kinase , putative 0.0167 0.033 0.1862
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0079 0.0367
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0072 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0155 0.0291
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0023
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0091 0.0165 0.0154
Toxoplasma gondii histone deacetylase HDAC2 0.082 0.1733 0.1733
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0234 0.0474 0.1568
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.002 0.0014 0.0044
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0022 0.0071
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0128
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0226 0.0457 0.1511
Echinococcus granulosus dnaJ subfamily B 0.0419 0.0871 0.2883
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0235 0.0475 0.0543
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0018 0.0009 0.0043
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0127 0.042
Plasmodium falciparum replication factor C subunit 1, putative 0.005 0.0078 0.0077
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0052 0.024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0052 0.024
Brugia malayi ancient conserved domain protein 2 0.002 0.0014 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.002 0.0014 0.0015
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0048 0.022
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.005 0.0078 0.0397
Brugia malayi hypothetical protein 0.0431 0.0896 0.4174
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Trichomonas vaginalis rotamase, putative 0.0065 0.0109 0.0581
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0022 0.0025
Echinococcus granulosus intestinal type alkaline phosphatase 0.0168 0.0331 0.1093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0005 0.0023
Brugia malayi CBS domain containing protein 0.002 0.0014 0.0062
Leishmania major CBS domain protein, conserved 0.002 0.0014 0.0065
Plasmodium falciparum flap endonuclease 1 0.0027 0.0027 0.0027
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0073 0.0341
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.01 0.0185 0.0859
Echinococcus multilocularis replication factor c subunit 1 0.005 0.0078 0.0088
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0065 0.0065
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.008 0.0266
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0005 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0022 0.01
Loa Loa (eye worm) hypothetical protein 0.0081 0.0144 0.067
Brugia malayi MH2 domain containing protein 0.0025 0.0023 0.0105
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0079 0.0403
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0005 0.0016
Leishmania major DNA polymerase kappa, putative 0.0102 0.0189 0.088
Echinococcus granulosus muscleblind protein 0.0307 0.063 0.2086
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0234 0.0474 0.2208
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Schistosoma mansoni coup transcription factor 0.0051 0.008 0.0266
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0073 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0107 0.0355
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0017 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0016 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Echinococcus multilocularis dna polymerase eta 0.0115 0.0217 0.0248
Onchocerca volvulus 0.0156 0.0305 0.3001
Loa Loa (eye worm) hypothetical protein 0.008 0.0142 0.0664
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0132
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0142 0.0662
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0155 0.0291
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0211 0.0241
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0005 0.0014
Schistosoma mansoni DNA helicase recq1 0.002 0.0014 0.0046
Echinococcus granulosus Niemann Pick C1 protein 0.0202 0.0405 0.134
Mycobacterium ulcerans cystathionine beta-synthase 0.002 0.0014 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.0648 0.302
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0034 0.0157
Loa Loa (eye worm) IMP dehydrogenase 1 0.002 0.0014 0.0065
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0026 0.0025
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0022 0.0103
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0211 0.0984
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0047 0.0067
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0378 0.0784 0.0771
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0065 0.0109 0.051
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0046 0.007 0.023
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0014 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0231 0.1287
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0231 0.1075
Chlamydia trachomatis DNA ligase 0.005 0.0078 0.0064
Trypanosoma brucei unspecified product 0.0061 0.0101 0.0473
Echinococcus multilocularis expressed conserved protein 0.019 0.0379 0.0433
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0107 0.0497
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0035 0.0035
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0014 0.0065
Mycobacterium ulcerans chorismate synthase 0.4663 1 1
Trichomonas vaginalis STE family protein kinase 0.0021 0.0016 0.004
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0041 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.0096 0.0446
Schistosoma mansoni amine oxidase 0.0041 0.0059 0.0194
Schistosoma mansoni hypothetical protein 0.0315 0.0648 0.2146
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0034 0.0034
Plasmodium falciparum histone deacetylase 1 0.082 0.1733 0.1733
Echinococcus granulosus Niemann Pick C1 protein 0.0289 0.0592 0.1959
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0018 0.002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0211 0.2694
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0226 0.0457 0.0522
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0047 0.0218
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0079 0.0089
Schistosoma mansoni hypothetical protein 0.0249 0.0505 0.1674
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0059 0.0096
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0047 0.0071
Mycobacterium ulcerans acetyl-CoA synthetase 0.0036 0.0047 0.0035
Schistosoma mansoni nuclear receptor 0.0024 0.0022 0.0073
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0168 0.0331 0.1093
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0072 0.0337
Echinococcus granulosus Smad4 0.0025 0.0023 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0073 0.0242
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0072 0.0124 0.058
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.0071
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0014 0.0014
Schistosoma mansoni brca1-associated protein (brap2) 0.0018 0.0009 0.0031
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0241 0.0489 0.0968
Schistosoma mansoni hypothetical protein 0.008 0.0142 0.0472
Schistosoma mansoni histone deacetylase hda2 0.0417 0.0866 0.2868
Echinococcus multilocularis Niemann Pick C1 protein 0.0202 0.0405 0.0463
Brugia malayi RNA binding protein 0.0064 0.0107 0.0497
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0142 0.0162
Schistosoma mansoni titin 0.0022 0.0018 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Brugia malayi serine/threonine kinase 12 0.0167 0.033 0.1536
Echinococcus granulosus expressed protein 0.0066 0.0113 0.0372
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0016 0.0015
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0014 0.0065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.008 0.0091
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0014 0.0046
Brugia malayi hypothetical protein 0.0124 0.0237 0.1104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0132
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0047 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0022 0.0071
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0016 0.0074
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0026 0.0119
Onchocerca volvulus 0.0036 0.0047 0.0455
Echinococcus granulosus dna polymerase kappa 0.0142 0.0275 0.0909
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0059 0.0058
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0065 0.0109 0.051
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Loa Loa (eye worm) hypothetical protein 0.0044 0.0064 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0072 0.0366
Brugia malayi topoisomerase 0.005 0.0078 0.0359
Echinococcus granulosus aurora kinase A 0.0167 0.033 0.1092
Schistosoma mansoni microtubule-associated protein tau 0.1418 0.302 1
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0211 0.1171
Plasmodium falciparum acyl-CoA synthetase 0.0091 0.0165 0.0165
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0234 0.0474 0.0542
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0047 0.0155
Echinococcus multilocularis importin subunit beta 1 0.003 0.0034 0.0038
Brugia malayi nuclear receptor RXR 0.0024 0.0022 0.01
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0066 0.0113 0.0523
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0271 0.126
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.005 0.0078 0.0397
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.008 0.0266
Echinococcus multilocularis GPCR, family 2 0.008 0.0142 0.0162
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.008 0.0142 0.0472
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0029 0.0136
Loa Loa (eye worm) hypothetical protein 0.0124 0.0237 0.1106
Schistosoma mansoni patched 1 0.0087 0.0157 0.0519
Schistosoma mansoni hypothetical protein 0.0686 0.1446 0.4789
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0253 0.0515 0.2397
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0168 0.0331 0.1093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Schistosoma mansoni ran 0.0022 0.0017 0.0056
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0022 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.0016 0.004
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.0047 0.0218
Schistosoma mansoni titin 0.0016 0.0005 0.0016
Loa Loa (eye worm) histone deacetylase 7A 0.1012 0.2146 1
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0211 0.0699
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.008 0.0091
Entamoeba histolytica hypothetical protein 0.0073 0.0127 0.0685
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.002 0.0014 0.0028
Echinococcus multilocularis nibrin 0.005 0.0078 0.0088
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0231 0.0447
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0039 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Schistosoma mansoni hypothetical protein 0.0084 0.015 0.0497
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0041 0.0059 0.0058
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0027 0.0091
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0041 0.0059 0.0194
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0034 0.011
Trypanosoma brucei DNA polymerase IV, putative 0.0142 0.0275 0.1282
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Leishmania major protein kinase, putative 0.0021 0.0016 0.0075
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.008 0.0372
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.002 0.0014 0.0065
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.005 0.0078 0.0397
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0231 0.1077
Echinococcus multilocularis hemicentin 1 0.0022 0.0018 0.002
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0072 0.0337
Plasmodium falciparum importin beta, putative 0.003 0.0034 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.013 0.0605
Giardia lamblia Hypothetical protein 0.0021 0.0016 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Echinococcus multilocularis Immunoglobulin 0.0036 0.0048 0.0054
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0065 0.0321
Brugia malayi phosphofructokinase 0.0112 0.0211 0.0981
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0059 0.0277
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0072 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Echinococcus multilocularis expressed protein 0.0066 0.0113 0.0128
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0073 0.0341
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0205 0.0412 0.1364
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.011 0.0206 0.096
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0047 0.0071
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0018 0.0009 0.0043
Mycobacterium tuberculosis Conserved protein 0.002 0.0014 0.0004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0005 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.008 0.0374
Trypanosoma cruzi histone deacetylase 1, putative 0.082 0.1733 0.8075
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.008 0.0266
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0072 0.0082
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.011 0.0206 0.096
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0078 0.0397
Echinococcus multilocularis Immunoglobulin 0.0036 0.0048 0.0054
Echinococcus multilocularis smad 0.0025 0.0023 0.0026
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0079 0.0259
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4078 0.8742 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0023
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0023
Schistosoma mansoni nephrin 0.0048 0.0073 0.0243
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.008 0.0266
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0065 0.0212
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0016 0.0071
Loa Loa (eye worm) chloride channel protein 7 0.002 0.0014 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0245
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0249 0.0505 0.1674
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.002 0.0014 0.0065
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0089 0.0161 0.0532
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0018 0.0009 0.0043
Brugia malayi ImpB/MucB/SamB family protein 0.0115 0.0217 0.1009
Trichomonas vaginalis AGC family protein kinase 0.0167 0.033 0.1862
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0021 0.0016 0.0075
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0022 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0072 0.0337
Loa Loa (eye worm) AUR protein kinase 0.0167 0.033 0.1538
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0073 0.0341
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0154 0.0507
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0017 0.0076
Loa Loa (eye worm) TK protein kinase 0.0017 0.0006 0.0027
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.002 0.0014 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.008 0.0785
Leishmania major histone deacetylase, putative 0.082 0.1733 0.8075
Leishmania major histone deacetylase, putative 0.1012 0.2146 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.002 0.0014 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0231 0.022
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0231 0.022
Leishmania major DNA polymerase kappa, putative 0.0027 0.0029 0.0136
Echinococcus granulosus smad 0.0025 0.0023 0.0075
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0072 0.0238
Entamoeba histolytica serine/threonine protein kinase, putative 0.0021 0.0016 0.004
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.008 0.0266
Echinococcus multilocularis histone deacetylase 1 0.082 0.1733 0.1982
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0023 0.0026
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.008 0.0374
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.0871 0.0996
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0211 0.1171
Brugia malayi nuclear hormone receptor 0.0051 0.008 0.0372
Loa Loa (eye worm) hypothetical protein 0.0144 0.0279 0.1301
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0022 0.0101
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0073 0.0073
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0022 0.0103
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.002 0.0014 0.0044
Echinococcus granulosus roundabout 2 0.0058 0.0096 0.0315
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.002 0.0014 0.0012
Schistosoma mansoni glutaminase 0.0282 0.0576 0.1908
Loa Loa (eye worm) hypothetical protein 0.0121 0.0231 0.1077
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0168 0.0331 0.0378
Loa Loa (eye worm) hypothetical protein 0.0044 0.0064 0.0298
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.002 0.0013 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0014 0.0014
Echinococcus multilocularis histone deacetylase 7 0.1012 0.2146 0.2455
Brugia malayi Calcitonin receptor-like protein seb-1 0.0253 0.0515 0.2397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Brugia malayi BRCA1-associated protein 2 containing protein 0.0018 0.0009 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.008 0.0091
Echinococcus multilocularis dual specificity 0.0187 0.0372 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0072 0.0366
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.008 0.0372
Schistosoma mansoni chloride channel protein 0.002 0.0014 0.0046
Schistosoma mansoni ap endonuclease 0.0019 0.0012 0.0039
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0047 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0305 0.0597
Schistosoma mansoni hypothetical protein 0.0085 0.0154 0.0509
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.077
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1229 0.1218
Leishmania major histone deacetylase, putative 0.1012 0.2146 1
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0619 0.1302 0.129
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0052 0.0058
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0005 0.0016
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.008 0.0374
Brugia malayi histone deacetylase 1 (HD1) 0.082 0.1733 0.8074
Schistosoma mansoni chloride channel protein 0.002 0.0014 0.0046
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0022 0.0071
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0027 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0113 0.0601
Schistosoma mansoni rotamase 0.0066 0.0113 0.0374
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0014 0.0015
Mycobacterium ulcerans hypothetical protein 0.0156 0.0305 0.0293
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0017 0.0054
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0271 0.1261
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0167 0.033 0.1862
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0006 0.0027
Trichomonas vaginalis glutaminase, putative 0.0282 0.0576 0.3289
Trichomonas vaginalis AGC family protein kinase 0.0167 0.033 0.1862
Leishmania major GTP-binding protein, putative 0.0022 0.0017 0.0078
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0041 0.0059 0.0058
Leishmania major chloride channel protein, putative 0.002 0.0014 0.0065
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0211 0.0402
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.008 0.0374
Brugia malayi hypothetical protein 0.0027 0.0028 0.0129
Loa Loa (eye worm) DR-78 0.0024 0.0022 0.0103
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0022 0.0073
Plasmodium vivax chorismate synthase 0.4663 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0028 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0014 0.0028
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.011 0.0206 0.0962
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0029 0.0029
Brugia malayi chloride channel protein 7 0.002 0.0014 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.013 0.0605
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0073 0.0073
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0187 0.0372 0.1732
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0016 0.0038
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.026 0.0528 0.1748
Leishmania major UDP-galactopyranose mutase 0.0041 0.0059 0.0274
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.008 0.0266
Echinococcus granulosus cpg binding protein 0.0061 0.0101 0.0332
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0035 0.0035
Brugia malayi hypothetical protein 0.0041 0.0059 0.0271
Toxoplasma gondii peptidylprolyl isomerase 0.0065 0.0109 0.0109
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0029 0.0136
Schistosoma mansoni hypothetical protein 0.0084 0.015 0.0497
Plasmodium vivax DNA repair protein REV1, putative 0.0027 0.0029 0.0029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.008 0.0264
Plasmodium falciparum histone deacetylase 2 0.1012 0.2146 0.2146
Echinococcus multilocularis bloom syndrome protein 0.002 0.0014 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.008 0.0264
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0047 0.0071
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.005 0.0078 0.0397
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0066 0.0113 0.0526
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.0047 0.0035
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0047 0.0217
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0023 0.0108
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.077
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0132
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.002 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0267 0.0545 0.2541
Schistosoma mansoni nuclear hormone receptor 0.0051 0.008 0.0266
Trypanosoma cruzi DNA polymerase eta, putative 0.0115 0.0217 0.1011
Giardia lamblia Histone deacetylase 0.082 0.1733 1
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.005 0.0078 0.0066
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0039 0.0044
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0028 0.0132
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0059 0.0193
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0094 0.0437
Echinococcus granulosus defective proboscis extension response 0.0036 0.0048 0.0157
Echinococcus multilocularis alkaline phosphatase 0.0168 0.0331 0.0378
Echinococcus granulosus alkaline phosphatase 0.0168 0.0331 0.1093
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.23 0.4916 1
Plasmodium falciparum protein MAM3, putative 0.002 0.0014 0.0013
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0047 0.0218
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0291 0.0965
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0073 0.0338
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0016 0.0024
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0041 0.0059 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Loa Loa (eye worm) loechrig isoform VII 0.0226 0.0457 0.2129
Leishmania major guanosine monophosphate reductase 0.002 0.0014 0.0065
Echinococcus multilocularis protein dispatched 1 0.0099 0.0183 0.0209
Schistosoma mansoni jumonji domain containing protein 0.0061 0.01 0.0333
Treponema pallidum Mg2+ transport protein (mgtE) 0.002 0.0014 0.0178
Echinococcus multilocularis tumor protein p63 0.1017 0.2158 0.2469
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0065
Brugia malayi Prion-like- 0.0022 0.0018 0.0081
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0211 0.1171
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0014 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0271 0.0897
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0091 0.0165 0.0151
Loa Loa (eye worm) hypothetical protein 0.0595 0.125 0.5825
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0108 0.0356
Leishmania major inosine-5-monophosphate dehydrogenase 0.002 0.0014 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0047 0.0215
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0028 0.0094
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0057 0.0275
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0079 0.0389
Echinococcus granulosus Protein patched homolog 1 0.0087 0.0157 0.0518
Echinococcus granulosus snurportin 1 0.0315 0.0648 0.2145
Loa Loa (eye worm) histone deacetylase 3 0.082 0.1733 0.8075
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0619 0.1302 0.1292
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0079 0.0403
Echinococcus multilocularis 0.0041 0.0059 0.0067
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0047 0.0071
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0022 0.0212
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0087 0.0157 0.0731
Onchocerca volvulus Tyrosine kinase homolog 0.0486 0.1016 1
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0072 0.024
Schistosoma mansoni histone deacetylase 4 5 0.1012 0.2146 0.7107
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0014 0.0065
Echinococcus granulosus titin 0.0016 0.0005 0.0014
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0154 0.0509
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0006 0.0006
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0022 0.0071
Loa Loa (eye worm) RecQ helicase 0.002 0.0014 0.0065
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0202 0.0405 0.2297
Loa Loa (eye worm) hypothetical protein 0.0124 0.0237 0.1106
Giardia lamblia DINP protein human, muc B family 0.0102 0.0189 0.1029
Brugia malayi hypothetical protein 0.005 0.0078 0.0359
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0021 0.0016 0.0052
Schistosoma mansoni nephrin 0.0022 0.0018 0.0059
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0014 0.0015
Toxoplasma gondii exonuclease III APE 0.0019 0.0012 0.0012
Schistosoma mansoni histone deacetylase 0.082 0.1733 0.5738
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0211 0.0697
Trypanosoma brucei histone deacetylase 1 0.082 0.1733 0.8075
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0047 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0154 0.0507
Brugia malayi Importin beta-1 subunit 0.003 0.0034 0.0154
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.002 0.0014 0.0004
Brugia malayi Histone deacetylase family protein 0.1012 0.2146 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0018 0.0084
Trichomonas vaginalis histone deacetylase, putative 0.082 0.1733 1
Brugia malayi RNA, U transporter 1 0.0084 0.0151 0.07
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0065 0.0109 0.051
Leishmania major hypothetical protein, unknown function 0.0014 0.0001 0.0002
Echinococcus granulosus neuroglian 0.0022 0.0018 0.0058
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0052 0.0169
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.002 0.0014 0.0062
Loa Loa (eye worm) glutaminase 2 0.0282 0.0576 0.2685
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0021 0.0016 0.0016
Brugia malayi histone deacetylase 3 (HD3) 0.082 0.1733 0.8074
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.008 0.0091
Echinococcus multilocularis Niemann Pick C1 protein 0.0289 0.0592 0.0677
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0073 0.037
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Plasmodium vivax acyl-CoA synthetase, putative 0.0091 0.0165 0.0165
Mycobacterium tuberculosis Possible oxidoreductase 0.0041 0.0059 0.0096
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0059 0.0277
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0374
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0018 0.0009 0.0009
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.0581 0.7416
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.002 0.0014 0.0014
Echinococcus granulosus dna polymerase eta 0.0115 0.0217 0.0717
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.0016 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0011 0.005
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0078 0.0397
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0231 0.0443
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0154 0.0716
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.008 0.0374
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0036 0.0047 0.0035
Brugia malayi Latrophilin receptor protein 2 0.008 0.0142 0.0662
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.008 0.0374
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Brugia malayi protein unc-22 0.0016 0.0005 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0142 0.0275 0.1542
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.077
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0005 0.0014
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0018 0.0172
Schistosoma mansoni DNA polymerase eta 0.0115 0.0217 0.0719
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0013 0.0063
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0341
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Trypanosoma cruzi histone deacetylase 1, putative 0.082 0.1733 0.8075
Brugia malayi Muscleblind-like protein 0.0307 0.063 0.2935
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Toxoplasma gondii CBS domain-containing protein 0.002 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0057 0.0094 0.031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0047 0.0071
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0023
Brugia malayi jmjC domain containing protein 0.0064 0.0108 0.0499
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0073 0.0341
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.0047 0.0067
Brugia malayi nuclear receptor NHR-88 0.0051 0.008 0.0372
Loa Loa (eye worm) histone deacetylase 1 0.082 0.1733 0.8075
Schistosoma mansoni protein kinase subunit beta 0.0059 0.0097 0.0321
Schistosoma mansoni flap endonuclease-1 0.0024 0.0022 0.0073
Loa Loa (eye worm) RNA binding protein 0.0064 0.0107 0.0499
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0047 0.0215
Treponema pallidum hemolysin (tlyC) 0.002 0.0014 0.0178
Schistosoma mansoni cell adhesion molecule 0.0022 0.0018 0.0059
Onchocerca volvulus 0.0024 0.0022 0.0212
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0018 0.0058
Trypanosoma brucei protein kinase, putative 0.0051 0.0079 0.0367
Echinococcus granulosus phd:f box containing protein 0.0016 0.0005 0.0014
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.002 0.0014 0.0012
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0035 0.015
Leishmania major hypothetical protein, conserved 0.0026 0.0026 0.0119
Onchocerca volvulus 0.0036 0.0047 0.0455
Loa Loa (eye worm) hypothetical protein 0.0115 0.0217 0.1011
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0027 0.0128
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0016 0.0074
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0059 0.0274
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0036 0.0047 0.0035
Echinococcus granulosus H:Cl exchange transporter 4 0.002 0.0014 0.0044
Brugia malayi hypothetical protein 0.0017 0.0006 0.0025
Schistosoma mansoni smad1 5 8 and 0.0025 0.0023 0.0077
Echinococcus granulosus AMPK beta subunit 0.011 0.0206 0.0682
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0027 0.0128
Toxoplasma gondii histone deacetylase HDAC1 0.1012 0.2146 0.2146
Chlamydia trachomatis dehyroquinate synthase 0.0241 0.0489 0.0475
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0023 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.033 0.1093
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.001 0.0045
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0047 0.0047
Trypanosoma cruzi NIMA-related kinase, putative 0.0021 0.0016 0.0075
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0231 0.1077
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0079 0.0389
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.008 0.0091
Brugia malayi DKFZp564C0469 protein 0.005 0.0078 0.0359
Onchocerca volvulus Alicorn homolog 0.0096 0.0177 0.1734
Trypanosoma cruzi GMP reductase 0.002 0.0014 0.0065
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0167 0.033 0.1862
Trypanosoma brucei DNA polymerase IV, putative 0.0129 0.0247 0.1149
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0211 0.02
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0034 0.0157
Loa Loa (eye worm) hypothetical protein 0.0613 0.1289 0.6007
Entamoeba histolytica protein kinase, putative 0.0167 0.033 0.1862
Onchocerca volvulus 0.0032 0.0039 0.0379
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0215 0.0215
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0021 0.0016 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0059 0.0277
Brugia malayi nuclear hormone receptor 0.0024 0.0022 0.01
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0017 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0189 0.088
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0035 0.0449
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Schistosoma mansoni hypothetical protein 0.0085 0.0154 0.0509
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0073 0.0083
Echinococcus multilocularis cpg binding protein 0.0061 0.0101 0.0115
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0023
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0012 0.0055
Loa Loa (eye worm) hypothetical protein 0.0182 0.0362 0.1689
Leishmania major DNA polymerase eta, putative 0.0115 0.0217 0.1011
Trypanosoma cruzi histone deacetylase, putative 0.1012 0.2146 1
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.0018 0.0058
Entamoeba histolytica histone deacetylase, putative 0.082 0.1733 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0027 0.0027
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0027 0.0031
Leishmania major DNA polymerase eta, putative 0.0054 0.0086 0.0399
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0167 0.033 0.1862
Loa Loa (eye worm) hypothetical protein 0.005 0.0078 0.0362
Schistosoma mansoni DNA ligase IV 0.005 0.0078 0.0257
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0014 0.0063
Loa Loa (eye worm) transcription factor SMAD2 0.0362 0.0749 0.349
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0021 0.0016 0.0075
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0016 0.0074
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0013 0.0063
Mycobacterium tuberculosis Conserved protein 0.002 0.0014 0.0004
Echinococcus granulosus histone deacetylase 6 0.1012 0.2146 0.7106
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0072 0.0337
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0014 0.0065
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0378 0.0784 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.008 0.0091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0271 0.0897
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0022 0.0212
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0079 0.0367
Brugia malayi nuclear receptor RXR 0.0027 0.0028 0.0129
Brugia malayi ecdysteroid receptor 0.0051 0.008 0.0372
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0271 0.1262
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0274
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0026 0.0119
Toxoplasma gondii hypothetical protein 0.0048 0.0073 0.0073
Schistosoma mansoni septate junction protein 0.0022 0.0018 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Trypanosoma brucei unspecified product 0.0129 0.0247 0.1149
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0211 0.0984
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0014 0.0065
Schistosoma mansoni amine oxidase 0.0041 0.0059 0.0194
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0102 0.0189 0.088
Echinococcus multilocularis roundabout 2 0.0058 0.0096 0.0109
Echinococcus multilocularis histone deacetylase 0.1012 0.2146 0.2455
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0018 0.0084
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0014 0.0065
Schistosoma mansoni terminal deoxycytidyl transferase 0.0089 0.0161 0.0532
Brugia malayi hypothetical protein 0.0024 0.0022 0.01
Loa Loa (eye worm) histone deacetylase 11 0.0417 0.0866 0.4036
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0022 0.0073
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0016 0.0071
Trypanosoma brucei chrX additional, unordered contigs 0.0027 0.0029 0.0136
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0014 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Onchocerca volvulus 0.0051 0.0079 0.077
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0211 0.0984
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0023
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0023 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0521 0.109 0.5077
Echinococcus granulosus neuroglian 0.0048 0.0073 0.0242
Loa Loa (eye worm) hypothetical protein 0.0307 0.063 0.2937
Loa Loa (eye worm) runx1 0.0054 0.0086 0.0402
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0012 0.0055
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0018 0.0084
Plasmodium vivax replication factor C subunit 1, putative 0.005 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0417 0.0866 0.4036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Echinococcus granulosus tumor protein p63 0.1017 0.2158 0.7147
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0378 0.0784 0.0773
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0072 0.0337
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0271 0.0895
Brugia malayi Protein kinase domain containing protein 0.0048 0.0072 0.0335
Schistosoma mansoni cell adhesion molecule 0.0022 0.0018 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0022 0.0025
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.0047 0.0046
Plasmodium falciparum chorismate synthase 0.4663 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.008 0.0372
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0016 0.0038
Onchocerca volvulus 0.0057 0.0094 0.0918
Echinococcus granulosus histone deacetylase 3 0.082 0.1733 0.5738
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0022 0.01
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.008 0.0785
Brugia malayi hypothetical protein 0.005 0.0078 0.0359
Mycobacterium ulcerans hypothetical protein 0.002 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0223
Trypanosoma brucei histone deacetylase 2 0.0417 0.0866 0.4036
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0005 0.0004
Entamoeba histolytica protein kinase, putative 0.0051 0.0079 0.0403
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0372 0.1231
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0619 0.1302 0.2628
Entamoeba histolytica hypothetical protein 0.0073 0.0127 0.0685
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0007 0.0021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0052 0.0245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0231 0.0443
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0211 0.1171
Schistosoma mansoni Smad4 0.0025 0.0023 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.008 0.0372
Schistosoma mansoni nuclear receptor 0.0024 0.0022 0.0073
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0052 0.0171
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0005 0.0023
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0079 0.0078
Echinococcus multilocularis AMPK beta subunit 0.011 0.0206 0.0236
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0295
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0028 0.0032
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0072 0.0366
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0005 0.0005
Plasmodium vivax histone deacetylase 2, putative 0.1012 0.2146 0.2146
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Echinococcus granulosus histone deacetylase 1 0.082 0.1733 0.5738
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0065 0.0109 0.051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.008 0.0372
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0271 0.0309
Schistosoma mansoni thyroid hormone receptor 0.0051 0.008 0.0266
Schistosoma mansoni protein kinase subunit gamma 0.0226 0.0457 0.1513
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0072 0.0366
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0269 0.0257
Brugia malayi nuclear receptor NHR-88 0.0024 0.0022 0.01
Brugia malayi hypothetical protein 0.0044 0.0064 0.0296
Toxoplasma gondii aurora kinase 0.0167 0.033 0.033
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1229 0.1218
Toxoplasma gondii NEK kinase 0.0021 0.0016 0.0016
Brugia malayi polk-prov protein 0.0081 0.0144 0.0667
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0103
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0028 0.0129
Mycobacterium ulcerans monoamine oxidase 0.0041 0.0059 0.0047
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0035 0.0035
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0065 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0039 0.0129
Entamoeba histolytica hypothetical protein 0.0187 0.0372 0.2102
Echinococcus granulosus roundabout 2 0.0022 0.0018 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0078 0.0362
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0231 0.022
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0047 0.0035
Echinococcus granulosus hemicentin 1 0.0022 0.0018 0.0058
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0419 0.0871 0.2884
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0012 0.0037
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0041 0.0059 0.0067
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.008 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0073 0.0242
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0014 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0187 0.0372 0.2102
Loa Loa (eye worm) hypothetical protein 0.0121 0.0231 0.1077
Trypanosoma brucei DNA polymerase eta, putative 0.0115 0.0217 0.1011
Toxoplasma gondii histone lysine-specific demethylase 0.0041 0.0059 0.0059
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0014 0.0065
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0012 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0271 0.0309
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0047 0.0215
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0065
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0012 0.0015
Echinococcus multilocularis muscleblind protein 0.0307 0.063 0.072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0016 0.0038
Brugia malayi conserved hypotetical protein 0.0024 0.0022 0.01
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0052 0.0171
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0072 0.0337
Toxoplasma gondii NEK kinase 0.0021 0.0016 0.0016
Schistosoma mansoni lozenge 0.0054 0.0086 0.0286
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0052 0.0169
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0005 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0039 0.0129
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0014 0.0046
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0108 0.0354
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.008 0.0266
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.082 0.1733 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0275 0.1282
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0434 0.2023
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0018 0.002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.01 0.0114
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0291 0.0333
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0187 0.0372 0.1732
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.011 0.0206 0.1131
Schistosoma mansoni cell adhesion molecule 0.0046 0.007 0.0232
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0016 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0155 0.0291
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0167 0.033 0.1092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0581 0.3317
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0018 0.0081
Echinococcus multilocularis histone deacetylase 6 0.103 0.2185 0.2499
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.0142 0.0275 0.0264
Schistosoma mansoni neuroglian 0.0022 0.0018 0.0059
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.0018 0.002
Brugia malayi loechrig isoform VII 0.0226 0.0457 0.2127
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0619 0.1302 0.1302
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0035 0.015
Toxoplasma gondii ATPase, AAA family protein 0.005 0.0078 0.0078
Loa Loa (eye worm) acetyltransferase 0.0149 0.0291 0.1358
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0029 0.0136
Mycobacterium ulcerans oxidoreductase 0.0041 0.0059 0.0047
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0012 0.0013
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0052 0.0169
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0084
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0016 0.0074
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0016 0.0074
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.0047 0.0046
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.008 0.0264
Loa Loa (eye worm) AUR protein kinase 0.0167 0.033 0.1538
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0231 0.1077
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0154 0.0509

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 7 uM Concentration required to inhibit SARS-CoV 3CL protease catalyzed cleavage of fluorogenic peptide Dabcyl-KTSAVLQSGFRKME-Edans by 50% ChEMBL. 15974598

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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