Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0128 | 0.1268 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0683 | 0.0633 |
Schistosoma mansoni | amine GPCR | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0683 | 0.0756 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1732 | 0.2016 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0195 | 0.0169 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0195 | 0.2803 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1303 | 0.1501 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0557 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0052 | 0.0673 | 0.1127 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0195 | 0.2803 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0421 | 0.161 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0195 | 0.0169 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0506 | 0.1018 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | Melatonin receptor type 1A | 0.0024 | 0.0155 | 0.0121 |
Trypanosoma cruzi | ISWI complex protein | 0.0034 | 0.0348 | 0.0455 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0024 | 0.0155 | 0.0101 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | biogenic amine receptor | 0.0024 | 0.0155 | 0.0443 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.0128 | 0.0258 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0249 | 0.0234 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0024 | 0.0155 | 0.0141 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | Serotonin receptor | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0109 | 0.1732 | 0.7361 |
Brugia malayi | sulfakinin receptor protein | 0.0024 | 0.0155 | 0.0121 |
Trypanosoma cruzi | ISWI complex protein | 0.0034 | 0.0348 | 0.0455 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.0506 | 0.0454 |
Plasmodium vivax | SET domain protein, putative | 0.0067 | 0.0958 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | amine GPCR | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | putative neuropeptide receptor | 0.0024 | 0.0155 | 0.0121 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0506 | 0.078 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | muscleblind protein | 0.0171 | 0.2876 | 0.2838 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0506 | 0.1982 |
Echinococcus multilocularis | serotonin receptor | 0.0024 | 0.0155 | 0.0101 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.0128 | 0.2016 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0067 | 0.0958 | 0.0909 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0683 | 0.0633 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0683 | 0.0756 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0195 | 0.2803 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0249 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0506 | 0.078 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0195 | 0.2803 |
Echinococcus multilocularis | fmrfamide receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0024 | 0.0155 | 0.0101 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0284 | 0.4965 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1732 | 0.2016 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0195 | 0.0169 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0067 | 0.0958 | 0.3964 |
Echinococcus multilocularis | somatostatin receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | muscleblind protein | 0.0171 | 0.2876 | 0.2838 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0195 | 0.0137 |
Brugia malayi | follicle stimulating hormone receptor | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0024 | 0.0155 | 0.0443 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Brugia malayi | Dopamine receptor | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0052 | 0.0673 | 0.0744 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0423 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0128 | 0.0258 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.0506 | 0.0454 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | Bromodomain containing protein | 0.0168 | 0.2819 | 0.3322 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0195 | 0.0137 |
Brugia malayi | Serotonin receptor | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | myosin xvIII | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0038 | 0.0421 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1401 | 0.1618 |
Schistosoma mansoni | biogenic amine receptor | 0.0024 | 0.0155 | 0.0443 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0073 | 0.0024 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0683 | 0.2761 |
Trypanosoma brucei | ISWI complex protein | 0.0034 | 0.0348 | 0.0701 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0195 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | Muscleblind-like protein | 0.0171 | 0.2876 | 0.3391 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0024 | 0.0155 | 0.0101 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0249 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0024 | 0.0155 | 0.0443 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0249 | 0.0249 |
Echinococcus multilocularis | neuropeptide receptor | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | neuropeptide receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | Dopamine receptor protein 1 | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | GnHR receptor homolog | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0128 | 0.0075 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0024 | 0.0155 | 0.0101 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0195 | 0.0137 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Leishmania major | DNA polymerase eta, putative | 0.0036 | 0.0389 | 0.0538 |
Schistosoma mansoni | neuropeptide receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 0.0128 | 0.0327 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0506 | 0.1982 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0534 | 0.9574 | 1 | |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.0128 | 0.0089 |
Brugia malayi | Pre-SET motif family protein | 0.0469 | 0.8377 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0683 | 0.2761 |
Brugia malayi | G-protein coupled receptor | 0.0024 | 0.0155 | 0.0121 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0052 | 0.0673 | 0.1356 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0683 | 0.0633 |
Brugia malayi | PHD-finger family protein | 0.0056 | 0.0746 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | MH2 domain containing protein | 0.0269 | 0.4684 | 0.5563 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0569 | 0.226 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.2642 | 0.3109 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0024 | 0.0155 | 0.0101 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | fmrfamide receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.0506 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0195 | 0.2803 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0067 | 0.0958 | 0.3964 |
Echinococcus granulosus | serotonin receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | fmrfamide receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0067 | 0.0958 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0073 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | opsin-like receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | Pre-SET motif family protein | 0.0067 | 0.0958 | 0.1086 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0106 | 0.1663 | 0.1618 |
Schistosoma mansoni | neuropeptide receptor | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | opsin-like receptor | 0.0024 | 0.0155 | 0.0443 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0249 | 0.0501 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0249 | 0.0234 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0195 | 0.0169 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 0.0128 | 0.0327 |
Echinococcus multilocularis | allatostatin A receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | Trypsin family protein | 0.0109 | 0.1732 | 0.2016 |
Echinococcus multilocularis | dna polymerase eta | 0.0052 | 0.0673 | 0.0623 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0269 | 0.4684 | 0.5563 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | amine GPCR | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0269 | 0.4684 | 0.5563 |
Echinococcus granulosus | neuropeptide receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0073 | 0.0024 |
Echinococcus granulosus | zinc finger protein | 0.0044 | 0.0525 | 0.0474 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | zinc finger protein | 0.0034 | 0.0348 | 0.1292 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0506 | 0.078 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.0506 | 0.078 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0038 | 0.0421 | 0.0369 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0024 | 0.0155 | 0.0443 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.0506 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | neuropeptide F receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0106 | 0.1663 | 0.7059 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 0.0128 | 0.0075 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0065 | 0.0912 | 0.0863 |
Schistosoma mansoni | biogenic amine receptor | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0195 | 0.3814 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0284 | 0.4965 | 0.5121 |
Brugia malayi | Dopamine receptor protein 2 | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0195 | 0.0137 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0195 | 0.3814 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0036 | 0.0389 | 0.0538 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0026 | 0.0195 | 0.0182 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0081 | 0.1202 | 0.1154 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0024 | 0.0155 | 0.0101 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.0506 | 0.3626 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0249 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 0.0128 | 0.0089 |
Onchocerca volvulus | 0.0109 | 0.1732 | 0.1792 | |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0128 | 0.0075 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0024 | 0.0155 | 0.0121 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0195 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | sex peptide receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0019 | 0.006 | 0.0007 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0024 | 0.0155 | 0.0121 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0195 | 0.0137 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0109 | 0.1732 | 0.7361 |
Schistosoma mansoni | neuropeptide receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | G-protein coupled receptor | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0128 | 0.1268 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0195 | 0.2803 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0423 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | hypothetical protein | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.0506 | 0.04 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0683 | 0.2761 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.13 | 0.1497 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0195 | 0.2803 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0024 | 0.0155 | 0.0141 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0557 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0073 | 0.0024 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | RE15519p | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0051 | 0.0648 | 0.0597 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0046 | 0.0569 | 0.0619 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | neuropeptide receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0024 | 0.0155 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.148 | 0.1713 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | bromodomain containing protein | 0.004 | 0.0446 | 0.0472 |
Echinococcus granulosus | sex peptide receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0073 | 0.0024 |
Echinococcus granulosus | somatostatin receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | allatostatin A receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | AKH receptor | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | histamine h1 receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0106 | 0.1663 | 0.1618 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2876 | 0.3391 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0171 | 0.2876 | 0.2838 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0195 | 0.0169 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0134 | 0.2186 | 0.2143 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | DNA polymerase eta | 0.0052 | 0.0673 | 0.2718 |
Echinococcus multilocularis | serotonin receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0024 | 0.0155 | 0.0121 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0036 | 0.0389 | 0.1974 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | zinc finger protein | 0.0044 | 0.0525 | 0.0474 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0024 | 0.0155 | 0.0101 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.0128 | 0.2016 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 0.0128 | 0.0075 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Brugia malayi | neuropeptide F receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0024 | 0.0155 | 0.0121 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0195 | 0.2803 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2876 | 0.3391 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0348 | 0.0455 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | dna polymerase eta | 0.0052 | 0.0673 | 0.0623 |
Echinococcus granulosus | orexin receptor type 2 | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0284 | 0.4965 | 0.5121 |
Brugia malayi | larval opioid receptor | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0469 | 0.8377 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0044 | 0.0525 | 0.2068 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.0506 | 0.0543 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0024 | 0.0155 | 0.0101 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0128 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Giardia lamblia | Thymidine kinase | 0.0284 | 0.4965 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0073 | 0.0024 |
Schistosoma mansoni | amine GPCR | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0051 | 0.0648 | 0.0597 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0024 | 0.0155 | 0.0443 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0421 | 0.161 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0506 | 0.04 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0683 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0081 | 0.1202 | 0.1154 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0348 | 0.1292 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0134 | 0.2186 | 0.2143 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1663 | 0.1934 |
Brugia malayi | G protein-coupled receptor | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0024 | 0.0155 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0673 | 0.0744 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Entamoeba histolytica | thymidine kinase, putative | 0.0284 | 0.4965 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0024 | 0.0155 | 0.0101 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Onchocerca volvulus | 0.0102 | 0.16 | 0.1654 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0051 | 0.0648 | 0.2607 |
Onchocerca volvulus | 0.0024 | 0.0155 | 0.0141 | |
Schistosoma mansoni | neuropeptide receptor | 0.0024 | 0.0155 | 0.0443 |
Brugia malayi | ORL1-like opioid receptor | 0.0024 | 0.0155 | 0.0121 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0106 | 0.1663 | 0.7059 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0249 | 0.1981 |
Onchocerca volvulus | 0.0067 | 0.0958 | 0.0981 | |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0024 | 0.0155 | 0.0101 |
Trichomonas vaginalis | set domain proteins, putative | 0.0534 | 0.9574 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0024 | 0.0155 | 0.0443 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0024 | 0.0155 | 0.0101 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0024 | 0.0155 | 0.0101 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0073 | 0.053 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0024 | 0.0155 | 0.0121 |
Schistosoma mansoni | amine GPCR | 0.0024 | 0.0155 | 0.0443 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0284 | 0.4965 | 1 |
Leishmania major | thymidine kinase, putative | 0.0284 | 0.4965 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0155 | 0.0443 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0024 | 0.0155 | 0.0443 |
Trypanosoma brucei | thymidine kinase | 0.0284 | 0.4965 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0249 | 0.0249 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0052 | 0.0673 | 0.1127 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0506 | 0.04 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0024 | 0.0155 | 0.0101 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0557 | 1 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0024 | 0.0155 | 0.0101 |
Brugia malayi | Inositol-1 | 0.0043 | 0.0506 | 0.0543 |
Schistosoma mansoni | bromodomain containing protein | 0.0142 | 0.2334 | 1 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0284 | 0.4965 | 0.5121 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC100 (binding) | = 5 uM | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
IC100 (binding) | = 5 uM | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
pIC100 (binding) | = -0.69 | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.