Detailed information for compound 331318

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.556 | Formula: C27H32F3N3O4
  • H donors: 2 H acceptors: 3 LogP: 1.33 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(F)(F)F.COCCn1cc(c2c1c(C)ccc2)C(=O)N1CCC(CC1)c1cccc(c1)CN
  • InChi: 1S/C25H31N3O2.C2HF3O2/c1-18-5-3-8-22-23(17-28(24(18)22)13-14-30-2)25(29)27-11-9-20(10-12-27)21-7-4-6-19(15-21)16-26;3-2(4,5)1(6)7/h3-8,15,17,20H,9-14,16,26H2,1-2H3;(H,6,7)
  • InChiKey: UELMZKNJKFVOKF-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tryptase alpha/beta 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Trypsin family protein tryptase alpha/beta 1 275 aa 288 aa 25.4 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis brca1-associated protein, putative 0.0019 0.0015 0.0068
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0058 0.0251
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0371 0.1187
Leishmania major GTP-binding protein, putative 0.0022 0.0023 0.009
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0112 0.0218 0.0973
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0104 0.0568
Brugia malayi CXXC zinc finger family protein 0.0058 0.0101 0.045
Trichomonas vaginalis BRCA1-associated protein, putative 0.0019 0.0015 0.0068
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0223 0.0994
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0026 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0371 0.1187
Loa Loa (eye worm) hypothetical protein 0.0606 0.1296 0.5833
Mycobacterium ulcerans acyl-CoA synthetase 0.0144 0.0287 0.0285
Schistosoma mansoni amine oxidase 0.0041 0.0064 0.0206
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.01 0.0192 0.0861
Echinococcus granulosus para nitrobenzyl esterase 0.0067 0.0121 0.0388
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Mycobacterium ulcerans acetyl-CoA synthetase 0.0042 0.0066 0.0064
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0209 0.043 0.1378
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.002 0.0077
Treponema pallidum hemolysin (tlyC) 0.0021 0.002 0.0187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0223 0.123
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0026 0.0115
Mycobacterium ulcerans monoamine oxidase 0.0041 0.0064 0.0062
Echinococcus granulosus serine:threonine kinase SAD 1 0.0049 0.0081 0.0258
Plasmodium vivax importin-beta 2, putative 0.003 0.004 0.0038
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0016 0.0018
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0054 0.0504
Brugia malayi hypothetical protein 0.0037 0.0055 0.0245
Entamoeba histolytica histone deacetylase, putative 0.0835 0.1795 1
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Trypanosoma cruzi histone deacetylase, putative 0.103 0.2222 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0032 0.003
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0056 0.0248
Loa Loa (eye worm) hypothetical protein 0.0144 0.0287 0.129
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0085 0.0378
Loa Loa (eye worm) hypothetical protein 0.0178 0.0363 0.1632
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0005 0.0012
Toxoplasma gondii NEK kinase 0.0022 0.0022 0.002
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.009 0.0392
Mycobacterium ulcerans carboxylesterase, LipT 0.0067 0.0121 0.0119
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0021 0.002 0.0035
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0042 0.015
Trypanosoma brucei histone deacetylase, putative 0.103 0.2222 1
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0023 0.0024 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Loa Loa (eye worm) patched family protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0026 0.0115
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0022 0.0087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0026 0.003
Leishmania major protein kinase, putative 0.0022 0.0022 0.0087
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0085 0.0378
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Echinococcus granulosus roundabout 2 0.006 0.0105 0.0335
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0066 0.0118 0.0117
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Leishmania major trypanothione reductase 0.0037 0.0056 0.024
Giardia lamblia Replication factor C, subunit 1 0.006 0.0104 0.0568
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.004 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0072 0.0387
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.002 0.0187
Onchocerca volvulus 0.0016 0.001 0.009
Trypanosoma cruzi histone deacetylase, putative 0.0424 0.09 0.4043
Trypanosoma cruzi histone deacetylase 1, putative 0.0835 0.1795 0.8077
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.001 0.0033
Brugia malayi hypothetical protein 0.0024 0.0026 0.0115
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0067 0.0121 0.0662
Loa Loa (eye worm) histone deacetylase 1 0.0835 0.1795 0.8078
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0048 0.0206
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.016 0.0321
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0065 0.0116 0.051
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0042 0.0066 0.0287
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0085 0.0272
Onchocerca volvulus 0.0067 0.0121 0.1144
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0027 0.0112
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.004 0.0038
Mycobacterium ulcerans dehydrogenase 0.0041 0.0064 0.0062
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0022 0.0093
Mycobacterium ulcerans hypothetical protein 0.0021 0.002 0.0017
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0032 0.003
Brugia malayi hypothetical protein 0.0067 0.0121 0.0542
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0022 0.0106
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0042 0.0066 0.0287
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0033
Echinococcus multilocularis Immunoglobulin 0.0037 0.0055 0.0062
Brugia malayi hypothetical protein 0.0017 0.0011 0.0047
Echinococcus granulosus roundabout 2 0.0023 0.0024 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0058 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Mycobacterium tuberculosis Possible oxidoreductase 0.0041 0.0064 0.0125
Mycobacterium ulcerans acyl-CoA synthetase 0.0144 0.0287 0.0285
Toxoplasma gondii CBS family protein 0.0021 0.002 0.0018
Trichomonas vaginalis STE family protein kinase 0.0022 0.0022 0.0108
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0054 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0186 0.0379 0.1704
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Plasmodium vivax histone deacetylase, putative 0.103 0.2222 0.2221
Entamoeba histolytica hypothetical protein 0.0037 0.0055 0.0224
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0223 0.0714
Loa Loa (eye worm) glutaminase 2 0.0287 0.06 0.2698
Brugia malayi topoisomerase 0.006 0.0104 0.0466
Loa Loa (eye worm) acetyltransferase 0.0152 0.0306 0.1374
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0026 0.003
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0064 0.0275
Onchocerca volvulus Alicorn homolog 0.0098 0.0188 0.1773
Onchocerca volvulus 0.0042 0.0066 0.0621
Onchocerca volvulus 0.0041 0.0064 0.0602
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0085 0.0378
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0043
Schistosoma mansoni hypothetical protein 0.0096 0.0185 0.0591
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.016 0.0321
Brugia malayi hypothetical protein 0.0024 0.0026 0.0115
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0018 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Loa Loa (eye worm) patched family protein 0.0012 0.0002 0.0003
Toxoplasma gondii histone deacetylase HDAC1 0.103 0.2222 0.2221
Brugia malayi histone deacetylase 3 (HD3) 0.0835 0.1795 0.8078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Toxoplasma gondii NEK kinase 0.0022 0.0022 0.002
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0382 0.0807 0.8819
Brugia malayi ecdysone receptor 0.0024 0.0026 0.0115
Giardia lamblia Kinase, CMGC CDK 0.0048 0.008 0.0431
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0081 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0112 0.0218 0.0973
Echinococcus granulosus replication factor c subunit 1 0.006 0.0104 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0104 0.0568
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0042
Echinococcus multilocularis histone deacetylase 8 0.0424 0.09 0.101
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Schistosoma mansoni septate junction protein 0.0023 0.0024 0.0076
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0144 0.0287 0.0285
Brugia malayi hypothetical protein 0.0027 0.0033 0.0144
Onchocerca volvulus Histone deacetylase 10 homolog 0.0424 0.09 0.8534
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0022 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0085 0.0378
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.002 0.0018
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.006 0.0104 0.0103
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0297 0.095
Toxoplasma gondii hypothetical protein 0.0096 0.0183 0.0182
Schistosoma mansoni protein kinase subunit beta 0.006 0.0105 0.0337
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0043
Toxoplasma gondii zinc finger cdgsh type protein 0.0014 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0085 0.0378
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.002 0.0084
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.001 0.0043
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.002 0.0095
Echinococcus multilocularis GPCR, family 2 0.0096 0.0185 0.0207
Echinococcus granulosus down syndrome cell adhesion 0.0012 0.0001 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.002 0.0018 0.0071
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.008 0.0348
Schistosoma mansoni chromosome transmission fidelity factor 0.006 0.0104 0.0334
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.002 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0144 0.0287 0.0285
Echinococcus multilocularis peroxidasin 0.0023 0.0024 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0083
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0033 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0085 0.0095
Loa Loa (eye worm) acetylcholinesterase 1 0.0399 0.0844 0.3797
Loa Loa (eye worm) AUR protein kinase 0.017 0.0346 0.1555
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0026 0.0115
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0084
Schistosoma mansoni protein kinase subunit beta 0.0112 0.0218 0.07
Brugia malayi hypothetical protein 0.006 0.0104 0.0466
Schistosoma mansoni flap endonuclease-1 0.0048 0.0079 0.0252
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0107 0.0208 0.0206
Schistosoma mansoni cell adhesion molecule 0.0012 0.0001 0.0003
Brugia malayi Fibronectin type III domain containing protein 0.0037 0.0055 0.0245
Loa Loa (eye worm) hypothetical protein 0.0399 0.0844 0.3797
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0625 0.1338 0.1336
Brugia malayi Protein kinase domain containing protein 0.0048 0.008 0.0356
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0083
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.002 0.0095
Brugia malayi Pax transcription activation domain interacting protein 0.006 0.0104 0.0466
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.001 0.0033
Loa Loa (eye worm) histone deacetylase 3 0.0835 0.1795 0.8078
Echinococcus granulosus dnaJ subfamily B 0.0426 0.0904 0.2895
Schistosoma mansoni phd/f-box containing protein 0.0016 0.001 0.0033
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0017
Plasmodium falciparum importin beta, putative 0.003 0.004 0.0038
Brugia malayi hypothetical protein 0.0044 0.0071 0.0317
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0005 0.0017
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0085 0.0272
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0544 0.1161 0.2357
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0022 0.0087
Echinococcus granulosus histone deacetylase 0.103 0.2222 0.7116
Loa Loa (eye worm) hypothetical protein 0.0107 0.0208 0.0934
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0045 0.0044
Onchocerca volvulus 0.0012 0.0002 0.0007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0084
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.002 0.0063
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.01 0.0192 0.0861
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.0502 0.2257
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0223 0.1001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.006 0.0105 0.0118
Loa Loa (eye worm) hypothetical protein 0.0159 0.032 0.1438
Brugia malayi protein C24B5.3 0.0012 0.0002 0.0003
Brugia malayi hypothetical protein 0.0126 0.025 0.1123
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Trypanosoma brucei histone deacetylase 1 0.0835 0.1795 0.8077
Leishmania major chloride channel protein, putative 0.0021 0.002 0.0077
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0032 0.003
Schistosoma mansoni histone deacetylase 0.0835 0.1795 0.5749
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.002 0.0077
Schistosoma mansoni 3-dehydroquinate synthase 0.0243 0.0505 0.1618
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0026 0.0085
Plasmodium vivax serine/threonine protein kinase 6, putative 0.017 0.0346 0.0345
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Echinococcus granulosus neuroligin 0.0067 0.0121 0.0388
Plasmodium falciparum serine/threonine protein kinase, putative 0.017 0.0346 0.0345
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0085 0.0798
Echinococcus granulosus titin 0.0016 0.001 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0223 0.2417
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0001 0.0003
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0235 0.0486 0.0546
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0012 0.004
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.002 0.0022
Echinococcus multilocularis aurora kinase A 0.017 0.0346 0.0388
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0371 0.1665
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0195 0.0392
Echinococcus multilocularis histone deacetylase 6 0.1049 0.2262 0.2538
Brugia malayi nuclear receptor RXR 0.0027 0.0033 0.0144
Loa Loa (eye worm) hypothetical protein 0.0399 0.0844 0.3797
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0032 0.003
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0625 0.1338 0.1336
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0058 0.0251
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0026 0.0085
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0264 0.0551 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0058 0.0311
Schistosoma mansoni lozenge 0.0055 0.0094 0.0302
Brugia malayi serine/threonine-protein kinase 6 0.017 0.0346 0.1555
Brugia malayi chloride channel protein 7 0.0021 0.002 0.0084
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0003 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0026
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.008 0.0348
Echinococcus multilocularis titin 0.0012 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0042 0.0066 0.0295
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.008 0.0431
Echinococcus granulosus peroxidasin 0.0023 0.0024 0.0076
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0026 0.003
Loa Loa (eye worm) patched family protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi tailless protein 0.0024 0.0026 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0195 0.0392
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0306 0.0343
Trypanosoma cruzi FHA domain containing protein, putative 0.006 0.0104 0.0459
Echinococcus granulosus intestinal type alkaline phosphatase 0.0171 0.0346 0.111
Brugia malayi nuclear receptor NHR-88 0.0024 0.0026 0.0115
Brugia malayi Pre-SET motif family protein 0.022 0.0453 0.2038
Echinococcus multilocularis nibrin 0.006 0.0104 0.0117
Brugia malayi hypothetical protein 0.0041 0.0064 0.0285
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0049 0.0081 0.0352
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.001 0.0034
Echinococcus multilocularis geminin 0.05 0.1065 0.1195
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Schistosoma mansoni nephrin related 0.0012 0.0001 0.0003
Entamoeba histolytica acyl-coA synthetase, putative 0.0144 0.0287 0.1531
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.002 0.0095
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0042 0.0066 0.0295
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0026 0.0115
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.002 0.0077
Echinococcus granulosus cpg binding protein 0.0061 0.0108 0.0346
Brugia malayi hypothetical protein 0.0012 0.0002 0.0003
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.008 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Loa Loa (eye worm) hypothetical protein 0.0144 0.0287 0.129
Trypanosoma cruzi leucine rich repeat protein, putative 0.0014 0.0005 0.0012
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0022 0.002
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0011 0.0036
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0085 0.0272
Loa Loa (eye worm) loechrig isoform VII 0.023 0.0477 0.2144
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0144 0.0287 0.1283
Leishmania major hypothetical protein, unknown function 0.0014 0.0005 0.0012
Onchocerca volvulus 0.0012 0.0002 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Brugia malayi ancient conserved domain protein 4 0.0021 0.002 0.0084
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0054 0.0239
Echinococcus granulosus smad 0.0016 0.001 0.0033
Plasmodium falciparum protein MAM3, putative 0.0021 0.002 0.0018
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0021 0.002 0.0212
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0042 0.0066 0.0287
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0012 0.0001 0.0001
Echinococcus granulosus lachesin 0.0023 0.0024 0.0076
Toxoplasma gondii histone deacetylase HDAC4 0.0424 0.09 0.0898
Schistosoma mansoni nuclear receptor 0.0024 0.0026 0.0085
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0067 0.0121 0.0136
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.002 0.0035
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.001 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.008 0.0431
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0085 0.0095
Giardia lamblia Kinase, CMGC CDK 0.0048 0.008 0.0431
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0835 0.1795 1
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0116 0.013
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.002 0.0063
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0041 0.0064 0.0091
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0121 0.0242
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0022 0.0069
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0012 0.0001 0.0003
Schistosoma mansoni cpg binding protein 0.0058 0.0101 0.0323
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Trichomonas vaginalis helicase, putative 0.0013 0.0003 0.0002
Schistosoma mansoni protein kinase subunit gamma 0.023 0.0477 0.1528
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.006 0.0104 0.1265
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.002 0.0063
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0625 0.1338 0.1337
Mycobacterium tuberculosis Conserved protein 0.0021 0.002 0.0035
Brugia malayi Muscleblind-like protein 0.046 0.0978 0.4398
Trichomonas vaginalis antibiotic synthetase, putative 0.0042 0.0066 0.0355
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.008 0.0366
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0027 0.0139
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0223 0.117
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0116 0.0371
Mycobacterium ulcerans hypothetical protein 0.0021 0.002 0.0017
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0242 0.0487
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.002 0.0063
Echinococcus multilocularis protein patched 0.0088 0.0167 0.0187
Onchocerca volvulus 0.015 0.0301 0.2851
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.008 0.0431
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0065 0.0116 0.051
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0048 0.0206
Echinococcus multilocularis twitchin 0.0016 0.001 0.0012
Toxoplasma gondii ck2 beta subunit 0.0036 0.0054 0.0052
Entamoeba histolytica protein kinase, putative 0.0051 0.0087 0.0403
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus granulosus insulin growth factor binding 0.0012 0.0001 0.0003
Loa Loa (eye worm) glutathione reductase 0.0037 0.0056 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0081 0.0258
Echinococcus granulosus histone deacetylase 1 0.0835 0.1795 0.5749
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.002 0.0022
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0042 0.0066 0.0064
Schistosoma mansoni histone deacetylase 4 5 0.103 0.2222 0.7116
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.016 0.0321
Echinococcus granulosus expressed protein 0.0066 0.0119 0.0381
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0049 0.0081 0.0352
Trichomonas vaginalis DNA polymerase eta, putative 0.0163 0.0331 0.1831
Trichomonas vaginalis set domain proteins, putative 0.025 0.0519 0.2882
Mycobacterium tuberculosis Conserved protein 0.0021 0.002 0.0035
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0109 0.0349
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0011 0.0047
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0087 0.0386
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0185 0.0827
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0042 0.004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0056 0.0108
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.008 0.0348
Leishmania major mitochondrial DNA polymerase beta 0.0594 0.1269 0.5708
Entamoeba histolytica hypothetical protein 0.019 0.0389 0.2101
Echinococcus multilocularis smad 0.0016 0.001 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Loa Loa (eye worm) carboxylesterase 0.0399 0.0844 0.3797
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0331 0.0328
Brugia malayi hypothetical protein 0.0026 0.0032 0.0139
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0085 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.008 0.0348
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Brugia malayi protein unc-22 0.0016 0.001 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0223 0.123
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0223 0.0449
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.009
Schistosoma mansoni terminal deoxycytidyl transferase 0.0109 0.0212 0.0681
Leishmania major DNA polymerase kappa, putative 0.0034 0.0048 0.0206
Echinococcus multilocularis tumor protein p63 0.1024 0.2207 0.2476
Echinococcus multilocularis insulin growth factor binding 0.0012 0.0001 0.0001
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.009
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0026 0.0115
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0022 0.0087
Echinococcus multilocularis 0.0041 0.0064 0.0072
Loa Loa (eye worm) hypothetical protein 0.006 0.0105 0.0467
Giardia lamblia DINP protein human, muc B family 0.0123 0.0242 0.1335
Treponema pallidum fructose-bisphosphate aldolase 0.0431 0.0915 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0048 0.0206
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0026 0.003
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0037 0.0055 0.0177
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.001 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0042
Brugia malayi histone deacetylase 11 0.0424 0.09 0.4048
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0054 0.022
Mycobacterium ulcerans transcriptional regulator 0.0021 0.002 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0087 0.0403
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1251 0.1249
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0026 0.0115
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0431 0.0915 0.5057
Echinococcus multilocularis Protein lozenge 0.0055 0.0094 0.0106
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.002 0.0077
Echinococcus multilocularis neuroligin 0.0067 0.0121 0.0136
Trichomonas vaginalis AGC family protein kinase 0.017 0.0346 0.1917
Plasmodium falciparum histone deacetylase 2 0.103 0.2222 0.2221
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0087 0.0085
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0042 0.004
Echinococcus granulosus acetylcholinesterase 0.0399 0.0844 0.2704
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Schistosoma mansoni titin 0.0023 0.0024 0.0076
Echinococcus granulosus histone deacetylase 3 0.0835 0.1795 0.5749
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0085 0.0272
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0116 0.0371
Plasmodium falciparum chorismate synthase 0.4596 1 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0078 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0042 0.0066 0.013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0167 0.0918
Echinococcus granulosus carboxylesterase 5A 0.0399 0.0844 0.2704
Schistosoma mansoni roundabout 0.0023 0.0024 0.0076
Echinococcus granulosus neuroglian 0.0049 0.0082 0.0262
Trypanosoma cruzi DNA polymerase eta, putative 0.0136 0.0271 0.1209
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.002 0.0095
Toxoplasma gondii histone kinase SNF1, putative 0.0049 0.0081 0.0079
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0243 0.0505 0.0503
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0085 0.0095
Onchocerca volvulus 0.0051 0.0087 0.0814
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0087 0.0097
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0164 0.0184
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.002 0.0018
Echinococcus multilocularis roundabout 2 0.0023 0.0024 0.0027
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0072 0.007
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.017 0.0346 0.1862
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0223 0.0415
Schistosoma mansoni protein phosphatase 2C 0.0016 0.001 0.0033
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.009 0.0486
Schistosoma mansoni DNA ligase IV 0.006 0.0104 0.0334
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0021 0.002 0.0017
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0085 0.0095
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0223 0.0714
Trypanosoma cruzi histone deacetylase 1, putative 0.0835 0.1795 0.8077
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0109 0.0349
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.002 0.0063
Mycobacterium ulcerans hypothetical protein 0.0021 0.002 0.0017
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4098 0.8912 1
Echinococcus multilocularis cpg binding protein 0.0061 0.0108 0.0121
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Onchocerca volvulus 0.0042 0.0066 0.0621
Trichomonas vaginalis rotamase, putative 0.0065 0.0116 0.0631
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0085 0.0272
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0305 0.0639 0.2873
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0026 0.0243
Brugia malayi putative serine/threonine kinase SADA gamma 0.0049 0.0081 0.036
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.002 0.0018
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.008 0.0356
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0042 0.0066 0.0095
Leishmania major DNA polymerase kappa, putative 0.0123 0.0242 0.1078
Schistosoma mansoni microtubule-associated protein tau 0.1443 0.3122 1
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0015 0.0055
Loa Loa (eye worm) patched family protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0264 0.0551 0.2475
Leishmania major hypothetical protein, conserved 0.0112 0.0218 0.0973
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.009 0.0088
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0058 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0054 0.006
Schistosoma mansoni hypothetical protein 0.0087 0.0164 0.0525
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0181 0.033
Echinococcus granulosus serine:threonine protein kinase 12 B 0.017 0.0346 0.1109
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0116 0.0517
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0064 0.0206
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0167 0.0535
Echinococcus multilocularis Niemann Pick C1 protein 0.0206 0.0423 0.0475
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Brugia malayi hypothetical protein 0.0159 0.032 0.1438
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0058 0.0311
Plasmodium falciparum acyl-CoA synthetase 0.0107 0.0208 0.0207
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0798 0.1715 0.3461
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.0656 0.133
Loa Loa (eye worm) RecQ helicase 0.0021 0.002 0.0085
Echinococcus multilocularis histone deacetylase 6 0.103 0.2222 0.2493
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Schistosoma mansoni neuroglian 0.0023 0.0024 0.0076
Loa Loa (eye worm) hypothetical protein 0.0044 0.007 0.0313
Brugia malayi Smad1 0.0016 0.001 0.0043
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Echinococcus multilocularis dna polymerase eta 0.0136 0.0271 0.0304
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0003 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0026 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0032 0.0131
Brugia malayi Patched protein homolog 1 0.0012 0.0002 0.0003
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.017 0.0346 0.0388
Brugia malayi amine oxidase, flavin-containing family protein 0.0041 0.0064 0.0285
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.008 0.0348
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.017 0.0346 0.1862
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0185 0.0591
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0164 0.0525
Trichomonas vaginalis replication factor C large subunit, putative 0.006 0.0104 0.0568
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0085 0.0378
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0306 0.1374
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0022 0.0087
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0014 0.0005 0.0004
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.017 0.0346 0.1862
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0037 0.0055 0.0177
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0081 0.0436
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0041 0.0064 0.0206
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0085 0.0272
Echinococcus multilocularis flap endonuclease 1 0.0053 0.009 0.0101
Echinococcus multilocularis tyrosine protein kinase otk 0.0023 0.0024 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0116 0.0371
Schistosoma mansoni cellular tumor antigen P53 0.015 0.0301 0.0964
Onchocerca volvulus Protein patched homolog 0.0012 0.0002 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0048 0.0206
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0072 0.007
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0042 0.0066 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.008 0.0256
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0054 0.022
Echinococcus granulosus expressed conserved protein 0.0193 0.0396 0.1269
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0085 0.0378
Schistosoma mansoni hypothetical protein 0.0087 0.0164 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.008 0.0256
Schistosoma mansoni chloride channel protein 0.0021 0.002 0.0063
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0087 0.0277
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0239 0.0495 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0438 0.0931 0.4187
Schistosoma mansoni hypothetical protein 0.0089 0.0168 0.0537
Schistosoma mansoni glutaminase 0.0287 0.06 0.1922
Schistosoma mansoni patched 1 0.0088 0.0167 0.0535
Schistosoma mansoni hypothetical protein 0.0085 0.016 0.0513
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0045 0.0145
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Schistosoma mansoni chloride channel protein 0.0021 0.002 0.0063
Entamoeba histolytica hypothetical protein 0.0037 0.0055 0.0224
Brugia malayi RE40412p 0.0014 0.0005 0.002
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0022 0.0087
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0164 0.0525
Entamoeba histolytica protein kinase domain containing protein 0.019 0.0389 0.2101
Trichomonas vaginalis AGC family protein kinase 0.017 0.0346 0.1917
Brugia malayi Peroxidasin 0.0023 0.0024 0.0103
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0331 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0104 0.0568
Schistosoma mansoni ran 0.0022 0.0023 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0045 0.0145
Entamoeba histolytica protein kinase, putative 0.017 0.0346 0.1862
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0066 0.0287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0085 0.0378
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0041 0.0064 0.0063
Loa Loa (eye worm) AUR protein kinase 0.017 0.0346 0.1555
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0037 0.0055 0.0062
Echinococcus granulosus nibrin 0.006 0.0104 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0081 0.0258
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0049 0.0081 0.0091
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.016 0.0321
Loa Loa (eye worm) hypothetical protein 0.0186 0.0379 0.1704
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.001 0.0009
Echinococcus multilocularis roundabout 2 0.006 0.0105 0.0117
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0223 0.0994
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Brugia malayi CHE-14 protein 0.0088 0.0167 0.0748
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0181 0.0363
Echinococcus granulosus Immunoglobulin 0.0037 0.0055 0.0177
Mycobacterium ulcerans hypothetical protein 0.0144 0.0287 0.0285
Leishmania major protein kinase, putative 0.017 0.0346 0.1548
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0107 0.0208 0.0206
Brugia malayi MH2 domain containing protein 0.0242 0.0502 0.2257
Entamoeba histolytica Ran family GTPase 0.0022 0.0023 0.0044
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.002 0.0085
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.002 0.0035
Echinococcus multilocularis dnaJ subfamily B 0.0426 0.0904 0.1014
Toxoplasma gondii glycogen synthase, putative 0.0014 0.0005 0.0004
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0019 0.0015 0.0133
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0033
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0064 0.0206
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Giardia lamblia Aurora kinase 0.017 0.0346 0.1917
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0066 0.0287
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0042 0.0217
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.016 0.0321
Plasmodium falciparum serine/threonine protein kinase KIN 0.0049 0.0081 0.0079
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0042 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.001 0.0043
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Leishmania major DNA polymerase eta, putative 0.0136 0.0271 0.1209
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0067 0.0121 0.0388
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0239 0.0495 0.1584
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0146 0.0293 0.1316
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0085 0.0378
Trypanosoma brucei DNA polymerase IV, putative 0.015 0.0301 0.1347
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0022 0.0087
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Schistosoma mansoni hypothetical protein 0.0085 0.016 0.0513
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0022 0.0086
Plasmodium falciparum glutathione reductase 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Mycobacterium ulcerans chorismate synthase 0.4596 1 1
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Schistosoma mansoni nephrin 0.0023 0.0024 0.0076
Loa Loa (eye worm) hypothetical protein 0.0424 0.09 0.4048
Entamoeba histolytica hypothetical protein 0.0024 0.0027 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0064 0.0063
Plasmodium falciparum histone deacetylase 1 0.0835 0.1795 0.1794
Schistosoma mansoni hypothetical protein 0.0426 0.0904 0.2895
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0104 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0066 0.013
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0305 0.0639 0.2873
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0126 0.0249 0.0797
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0243 0.0505 0.1023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0085 0.0378
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0085 0.0378
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0345 0.0727 0.3271
Echinococcus granulosus tar DNA binding protein 0.0065 0.0116 0.0371
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0144 0.0287 0.0285
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0022 0.0086
Giardia lamblia Histone deacetylase 0.0835 0.1795 1
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.019 0.0389 0.174
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0042 0.0066 0.0065
Echinococcus multilocularis expressed conserved protein 0.0193 0.0396 0.0445
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.2266 0.4918 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0041 0.0064 0.0206
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0081 0.036
Entamoeba histolytica hypothetical protein 0.0037 0.0055 0.0224
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0014 0.0005 0.0004
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0042 0.0066 0.0065
Brugia malayi serine/threonine protein kinase 6 0.017 0.0346 0.1555
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0085 0.0272
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Schistosoma mansoni hypothetical protein 0.0249 0.0517 0.1657
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0223 0.025
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0022 0.002
Schistosoma mansoni cell adhesion molecule 0.0023 0.0024 0.0076
Trichomonas vaginalis AGC family protein kinase 0.017 0.0346 0.1917
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Trypanosoma brucei histone deacetylase 4 0.103 0.2222 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0067 0.0121 0.0388
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0022 0.0106
Echinococcus multilocularis titin 0.0012 0.0001 0.0001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0033 0.0105
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0021 0.002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0126 0.025 0.1123
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0015 0.0047
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0024 0.0027
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0112 0.0218 0.098
Echinococcus granulosus titin 0.0016 0.001 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0085 0.0378
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0064 0.0341
Echinococcus multilocularis hemicentin 1 0.0023 0.0024 0.0027
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0042 0.0066 0.013
Trypanosoma brucei unspecified product 0.0075 0.0139 0.0613
Brugia malayi hypothetical protein 0.0012 0.0002 0.0003
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0594 0.1269 0.5708
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0014 0.0005 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.004 0.0128
Onchocerca volvulus 0.0012 0.0002 0.0007
Brugia malayi hypothetical protein 0.006 0.0104 0.0466
Echinococcus granulosus dna polymerase eta 0.0136 0.0271 0.0867
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0023 0.0024 0.0218
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0055 0.0245
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Leishmania major DNA damage repair protein, putative 0.0034 0.0048 0.0206
Trypanosoma brucei trypanothione reductase 0.0037 0.0056 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Plasmodium vivax chorismate synthase 0.4596 1 1
Brugia malayi 6-phosphofructokinase 0.0114 0.0223 0.1001
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Brugia malayi hypothetical protein 0.0037 0.0055 0.0242
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0018 0.0071
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0022 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0005 0.0004
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0239 0.0495 0.2224
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0085 0.0272
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0022 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0166 0.0739
Schistosoma mansoni acetylcholinesterase 0.0067 0.0121 0.0388
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0109 0.0122
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0024 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Echinococcus granulosus snurportin 1 0.0321 0.0674 0.2159
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.001 0.0033
Echinococcus granulosus GPCR family 2 0.0096 0.0185 0.0591
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0042
Brugia malayi BRCA1-associated protein 2 containing protein 0.0019 0.0015 0.0063
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0058 0.0187
Brugia malayi Thioredoxin reductase 0.0037 0.0056 0.0248
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0107 0.0469
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Toxoplasma gondii histone lysine-specific demethylase 0.0041 0.0064 0.0063
Brugia malayi RNA, U transporter 1 0.0085 0.0161 0.072
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Plasmodium vivax acetyl-CoA synthetase, putative 0.0042 0.0066 0.0065
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0042 0.0066 0.0074
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0164 0.0184
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0112 0.0218 0.098
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Leishmania major histone deacetylase, putative 0.103 0.2222 1
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.002 0.0077
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0087 0.0378
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0045 0.0072 0.007
Plasmodium falciparum replication factor C subunit 1, putative 0.006 0.0104 0.0103
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0008
Brugia malayi hypothetical protein 0.0012 0.0002 0.0003
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.019 0.0389 0.174
Brugia malayi Patched related family protein 12 0.0012 0.0002 0.0003
Trichomonas vaginalis ran, putative 0.0022 0.0023 0.0112
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Brugia malayi steroid hormone receptor 0.0051 0.0085 0.0378
Echinococcus granulosus aurora kinase A 0.017 0.0346 0.1109
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Leishmania major 4-coumarate:coa ligase-like protein 0.0144 0.0287 0.1283
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0022 0.0108
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Echinococcus multilocularis acetylcholinesterase 0.0399 0.0844 0.0947
Echinococcus granulosus tumor protein p63 0.1024 0.2207 0.7069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0024 0.0103
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Mycobacterium ulcerans hypothetical protein 0.0313 0.0656 0.0654
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0042 0.004
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0042
Schistosoma mansoni nephrin 0.0049 0.0082 0.0262
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0022 0.0087
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0008 0.0026
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0104 0.0568
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.021 0.0432 0.0485
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0087 0.0386
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.002 0.0018
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0033 0.0105
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0043
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0042 0.0066 0.0064
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0171 0.0346 0.0389
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.002
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0066 0.0119 0.0533
Trypanosoma cruzi GMP reductase 0.0021 0.002 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0022 0.0038
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0625 0.1337 0.6015
Echinococcus granulosus BRCA1 associated protein 0.0019 0.0015 0.0047
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.008 0.009
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0098
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0042 0.0066 0.0064
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0195 0.0392
Trypanosoma cruzi histone deacetylase, putative 0.103 0.2222 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.1269 0.5708
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0112 0.0218 0.1205
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0045 0.0145
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0022 0.0069
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0012 0.0014
Giardia lamblia Hypothetical protein 0.0021 0.002 0.0095
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.006 0.0104 0.0173
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0084
Brugia malayi histone deacetylase 1 (HD1) 0.0835 0.1795 0.8078
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0037 0.0055 0.0175
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0164 0.0734
Onchocerca volvulus 0.0012 0.0002 0.0007
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0164 0.0525
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0382 0.0807 1
Echinococcus granulosus bloom syndrome protein 0.0021 0.002 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0371 0.1187
Schistosoma mansoni alkaline phosphatase 0.0171 0.0346 0.111
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.001 0.0033
Leishmania major importin beta-1 subunit, putative 0.0024 0.0027 0.0112
Trypanosoma brucei aurora B kinase 0.017 0.0346 0.1548
Brugia malayi protein C24B5.3 0.0012 0.0002 0.0003
Toxoplasma gondii IMP dehydrogenas 0.0021 0.002 0.0018
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0109 0.0212 0.0681
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0024 0.0027
Onchocerca volvulus 0.0012 0.0002 0.0007
Schistosoma mansoni alkaline phosphatase 0.0171 0.0346 0.111
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0144 0.0287 0.0285
Echinococcus multilocularis phd:f box containing protein 0.0016 0.001 0.0011
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0043
Echinococcus multilocularis BRCA1 associated protein 0.0019 0.0015 0.0017
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0171 0.0346 0.111
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0185 0.0827
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0176
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0087 0.0277
Brugia malayi Pre-SET motif family protein 0.0033 0.0045 0.0201
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0085 0.0095
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0085 0.0378
Leishmania major histone deacetylase, putative 0.0835 0.1795 0.8077
Loa Loa (eye worm) hypothetical protein 0.006 0.0105 0.0467
Leishmania major hypothetical protein, conserved 0.0021 0.002 0.0077
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.002 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0144 0.0287 0.129
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0259
Trypanosoma cruzi histone deacetylase, putative 0.103 0.2222 1
Entamoeba histolytica protein kinase domain containing protein 0.017 0.0346 0.1862
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0144 0.0287 0.129
Leishmania major CBS domain protein, conserved 0.0021 0.002 0.0077
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Echinococcus granulosus protein kinase shaggy 0.0051 0.0087 0.0277
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0116 0.0519
Echinococcus multilocularis histone deacetylase 1 0.0835 0.1795 0.2014
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0023 0.0024 0.0076
Echinococcus multilocularis expressed protein 0.0066 0.0119 0.0134
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0242 0.1078
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0008 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0064 0.0125
Onchocerca volvulus 0.0478 0.1017 0.965
Schistosoma mansoni topbp1 0.006 0.0104 0.0334
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.002 0.0077
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.008 0.0348
Plasmodium vivax histone deacetylase 2, putative 0.103 0.2222 0.2221
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0033 0.0146
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0005 0.0006
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0022 0.002
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0164 0.0525
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0531 0.1131 0.5091
Brugia malayi Histone deacetylase 1 0.0835 0.1795 0.8078
Mycobacterium tuberculosis Probable reductase 0.0085 0.016 0.0321
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.006 0.0104 0.0466
Brugia malayi Carboxylesterase family protein 0.0399 0.0844 0.3797
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0022 0.0106
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0085 0.0272
Schistosoma mansoni histone deacetylase 0.0835 0.1795 0.5749
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0042 0.0066 0.0095
Loa Loa (eye worm) histone deacetylase 11 0.0424 0.09 0.4048
Brugia malayi CLC chloride channel protein 0.0021 0.002 0.0084
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0042 0.0066 0.0065
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0116 0.0372
Schistosoma mansoni jumonji domain containing protein 0.0016 0.001 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0016
Treponema pallidum P26 0.0014 0.0005 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0144 0.0287 0.0579
Loa Loa (eye worm) RNA binding protein 0.0065 0.0116 0.0517
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0121 0.0388
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0014 0.0005 0.0004
Echinococcus multilocularis transfer RNA-Phe 0.0012 0.0001 0.0001
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0023 0.0021
Toxoplasma gondii histone deacetylase HDAC5 0.0424 0.09 0.0898
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0026 0.003
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0045 0.0145
Brugia malayi latrophilin 2 splice variant baaae 0.0208 0.0429 0.1926
Toxoplasma gondii peptidylprolyl isomerase 0.0065 0.0116 0.0114
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.0067
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0026 0.0115
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0096 0.0185 0.0591
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.002 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0085 0.0272
Trypanosoma brucei DNA polymerase eta, putative 0.0136 0.0271 0.1209
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0116 0.0371
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0016 0.0051
Loa Loa (eye worm) oxidoreductase 0.0042 0.0066 0.0295
Entamoeba histolytica acyl-CoA synthetase, putative 0.0144 0.0287 0.1531
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0022 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi hypothetical protein 0.0438 0.0931 0.4187
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.009 0.0486
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0066 0.013
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Onchocerca volvulus 0.0042 0.0066 0.0621
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0798 0.1715 0.1713
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0085 0.0272
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0017 0.0074
Brugia malayi Niemann-Pick C1 protein precursor 0.0206 0.0423 0.1903
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0163 0.0331 0.1831
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Brugia malayi ecdysteroid receptor 0.0051 0.0085 0.0378
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0021 0.002 0.0212
Brugia malayi TAR-binding protein 0.0065 0.0116 0.0517
Loa Loa (eye worm) hypothetical protein 0.0208 0.0429 0.1926
Schistosoma mansoni cell adhesion molecule 0.0023 0.0024 0.0076
Brugia malayi phosphofructokinase 0.0114 0.0223 0.1001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0045 0.0145
Chlamydia trachomatis protoporphyrinogen oxidase 0.0041 0.0064 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0022 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0399 0.0844 0.2704
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0026 0.0085
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0066 0.013
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0081 0.0436
Echinococcus granulosus histone deacetylase 6 0.103 0.2222 0.7116
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0061 0.0107 0.0105
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0042 0.0066 0.0064
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0022 0.002
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.008 0.0366
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0104 0.0568
Echinococcus granulosus phd:f box containing protein 0.0016 0.001 0.0033
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0065 0.0116 0.051
Leishmania major guanosine monophosphate reductase 0.0021 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0835 0.1795 0.8078
Schistosoma mansoni gliotactin 0.0067 0.0121 0.0388
Brugia malayi CBS domain containing protein 0.0021 0.002 0.0084
Chlamydia trachomatis DNA ligase 0.006 0.0104 0.0102
Brugia malayi ancient conserved domain protein 2 0.0021 0.002 0.0084
Leishmania major acetyl-CoA synthetase, putative 0.0042 0.0066 0.0287
Toxoplasma gondii exonuclease III APE 0.002 0.0017 0.0016
Brugia malayi Histone deacetylase family protein 0.103 0.2222 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0144 0.0287 0.129
Echinococcus granulosus nephrin 0.0012 0.0001 0.0003
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0625 0.1338 0.2692
Toxoplasma gondii hypothetical protein 0.0014 0.0005 0.0004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0109 0.0212 0.0427
Onchocerca volvulus 0.0012 0.0002 0.0007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0055 0.0061
Plasmodium vivax SET domain protein, putative 0.0033 0.0045 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0096 0.0185 0.0591
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0243 0.0505 0.0991
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0084
Echinococcus multilocularis microtubule associated protein 2 0.1443 0.3122 0.3503
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Echinococcus multilocularis histone deacetylase 0.103 0.2222 0.2493
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0223 0.1001
Brugia malayi ImpB/MucB/SamB family protein 0.0136 0.0271 0.1216
Onchocerca volvulus 0.0042 0.0066 0.0621
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0058 0.0065
Brugia malayi nuclear hormone receptor 0.0051 0.0085 0.0378
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Schistosoma mansoni cell adhesion molecule 0.0012 0.0001 0.0003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0295
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0085 0.0272
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0185 0.0827
Echinococcus multilocularis carboxylesterase 5A 0.0399 0.0844 0.0947
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0017 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Brugia malayi AMP-binding enzyme family protein 0.0144 0.0287 0.129
Toxoplasma gondii chorismate synthase, putative 0.4596 1 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.002 0.0077
Echinococcus multilocularis Smad4 0.0016 0.001 0.0012
Brugia malayi conserved hypotetical protein 0.0024 0.0026 0.0115
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0223 0.0994
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.0502 0.2257
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.006 0.0104 0.0102
Brugia malayi intracellular kinase 0.0051 0.0087 0.0386
Trichomonas vaginalis AGC family protein kinase 0.017 0.0346 0.1917
Brugia malayi Importin beta-1 subunit 0.003 0.004 0.0176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Echinococcus multilocularis snurportin 1 0.0321 0.0674 0.0756
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.008 0.0348
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.002 0.0077
Schistosoma mansoni hypothetical protein 0.0096 0.0185 0.0591
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0223 0.117
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis Immunoglobulin 0.0037 0.0055 0.0062
Mycobacterium ulcerans hypothetical protein 0.0034 0.0048 0.0046
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Trichomonas vaginalis glutaminase, putative 0.0287 0.06 0.3333
Plasmodium falciparum thioredoxin reductase 0.0013 0.0003 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0087 0.0468
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.002
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0346 0.1109
Plasmodium vivax replication factor C subunit 1, putative 0.006 0.0104 0.0103
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.006 0.0104 0.0503
Echinococcus granulosus dna polymerase kappa 0.0163 0.0331 0.1059
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.002 0.0085
Echinococcus granulosus Smad4 0.0016 0.001 0.0033
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0081 0.0352
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0171 0.0346 0.0389
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0054 0.0504
Echinococcus granulosus dual specificity 0.019 0.0389 0.1245
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0026 0.0085
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0057 0.0064
Schistosoma mansoni acetyl-CoA synthetase 0.0042 0.0066 0.0212
Echinococcus granulosus alkaline phosphatase 0.0171 0.0346 0.111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0371 0.1187
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0003 0.0001
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.019 0.0389 0.174
Loa Loa (eye worm) hypothetical protein 0.015 0.0301 0.1352
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0042 0.0427
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0112
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0024 0.0076
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.002 0.0084
Echinococcus granulosus leucine rich repeat containing protein 4 0.0012 0.0001 0.0003
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0022 0.0093
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0022 0.0093
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.0453 0.2038
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0104 0.0459
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0011 0.0047
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0206 0.0423 0.2295
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0022 0.0069
Brugia malayi Carboxylesterase family protein 0.0067 0.0121 0.0542
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0056 0.024
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.019 0.0389 0.1747
Schistosoma mansoni DNA helicase recq5 0.0021 0.002 0.0063
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0056 0.0054
Echinococcus multilocularis titin 0.0012 0.0001 0.0001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0085 0.0272
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Leishmania major hypothetical protein, conserved 0.0026 0.0032 0.0131
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0042 0.0066 0.0212
Loa Loa (eye worm) hypothetical protein 0.0088 0.0167 0.0748
Echinococcus multilocularis alkaline phosphatase 0.0171 0.0346 0.0389
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0026 0.0085
Leishmania major 4-coumarate:coa ligase-like protein 0.0144 0.0287 0.1283
Giardia lamblia Casein kinase II beta chain 0.0036 0.0054 0.0286
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0027 0.0139
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.001 0.0033
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0223 0.0221
Mycobacterium ulcerans glutaminase 0.0287 0.06 0.0598
Trichomonas vaginalis rotamase, putative 0.0066 0.0119 0.065
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0048 0.0206
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Onchocerca volvulus 0.0021 0.002 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0085 0.0272
Schistosoma mansoni slit 0.0012 0.0001 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0024 0.0103
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0022 0.0024
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.001 0.0043
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0017 0.0014
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0085 0.0378
Echinococcus granulosus importin subunit beta 1 0.003 0.004 0.0128
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0049 0.0081 0.036
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0144
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0087 0.0468
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0064 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0104 0.0568
Echinococcus multilocularis protoporphyrinogen oxidase 0.0041 0.0064 0.0072
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.008 0.009
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.002 0.0018 0.0196
Giardia lamblia DNA damage repair protein 0.0034 0.0048 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0058 0.0311
Onchocerca volvulus Tyrosine kinase homolog 0.0495 0.1054 1
Onchocerca volvulus 0.025 0.0519 0.4921
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0264 0.0551 0.1763
Giardia lamblia Kinase, NEK 0.0022 0.0022 0.0108
Toxoplasma gondii histone deacetylase HDAC2 0.0835 0.1795 0.1794
Echinococcus multilocularis AMPK beta subunit 0.0112 0.0218 0.0245
Schistosoma mansoni titin 0.0016 0.001 0.0033
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.008 0.0256
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0048 0.0078 0.025
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0167 0.0187
Toxoplasma gondii CBS domain-containing protein 0.0021 0.002 0.0018
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.0587 0.2634
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0015 0.0047
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0531 0.1131 0.5091
Schistosoma mansoni hypothetical protein 0.0085 0.016 0.0513
Toxoplasma gondii ATPase, AAA family protein 0.006 0.0104 0.0103
Trypanosoma brucei GMP reductase 0.0021 0.002 0.0077
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0066 0.0287
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0087 0.0378
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0014 0.0005 0.0004
Echinococcus granulosus titin 0.0012 0.0001 0.0003
Echinococcus multilocularis hemicentin 1 0.0023 0.0024 0.0027
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0022 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Loa Loa (eye worm) hypothetical protein 0.0206 0.0423 0.1903
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0026 0.0085
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0021 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0085 0.0378
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0223 0.1001
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0049 0.0081 0.0352
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0058 0.0187
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0087 0.0085
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0104 0.0459
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0054 0.0052
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0016 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trypanosoma cruzi histone deacetylase, putative 0.0424 0.09 0.4043
Loa Loa (eye worm) chloride channel 3 0.0021 0.002 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0223 0.123
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.002 0.0022
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0116 0.0372
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0185 0.0207
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0087 0.0403
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0058 0.0251
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0109 0.0122
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0264 0.0551 0.1763
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0042 0.0066 0.0064
Echinococcus granulosus roundabout 2 0.0023 0.0024 0.0076
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0014 0.0005 0.0004
Echinococcus multilocularis importin subunit beta 1 0.003 0.004 0.0045
Leishmania major hypothetical protein, conserved 0.0019 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0073 0.0133 0.0597
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0033 0.0144
Giardia lamblia Fructose-bisphosphate aldolase 0.0431 0.0915 0.5091
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.001 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0242 0.1078
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0055 0.0175
Schistosoma mansoni neuroligin 3 (S09 family) 0.0067 0.0121 0.0388
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0371 0.0416
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0026 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0085 0.0272
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0042 0.0066 0.0289
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0022 0.002
Schistosoma mansoni smad 0.0016 0.001 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0026 0.0115
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0144 0.0287 0.0285
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0054 0.0172
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0048 0.0047
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.002 0.0018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0144 0.0287 0.0579
Trypanosoma cruzi GMP reductase 0.0021 0.002 0.0077
Mycobacterium tuberculosis Carboxylesterase LipT 0.0067 0.0121 0.0242
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0306 0.098
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0027 0.0139
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0012 0.0001 0.0003
Brugia malayi nuclear receptor NHR-88 0.0051 0.0085 0.0378
Brugia malayi SWIRM domain containing protein 0.0041 0.0064 0.0285
Brugia malayi Carboxylesterase family protein 0.0399 0.0844 0.3797
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0054 0.0172
Brugia malayi glutathione reductase 0.0037 0.0056 0.0248
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0085 0.0095
Chlamydia trachomatis dehyroquinate synthase 0.0243 0.0505 0.0503
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0054 0.0231
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0021 0.002 0.0035
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0042 0.0066 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Echinococcus granulosus flap endonuclease 1 0.0053 0.009 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0104 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.001 0.0011
Plasmodium vivax protein kinase Crk2 0.0048 0.008 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0085 0.0378
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0085 0.0378
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0112 0.0218 0.0973
Brugia malayi Patched related family protein 10 0.0012 0.0002 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0022 0.0038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0245 0.0785
Echinococcus granulosus AMPK beta subunit 0.0112 0.0218 0.07
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0371 0.1187
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.001 0.0011
Echinococcus multilocularis protein dispatched 1 0.0101 0.0194 0.0218
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.002 0.0022
Onchocerca volvulus 0.0033 0.0045 0.0423
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.001 0.0033
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0066 0.0119 0.0533
Schistosoma mansoni tyrosine kinase 0.0027 0.0034 0.0109
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0085 0.0798
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.006 0.0105 0.0337
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0088 0.0166 0.0746
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0389 0.1245
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0012 0.0001 0.0003
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.008 0.009
Onchocerca volvulus 0.0014 0.0005 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0018 0.0071
Echinococcus granulosus muscleblind protein 0.046 0.0978 0.3131
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0048 0.0206
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0033 0.0144
Brugia malayi polk-prov protein 0.0088 0.0166 0.0746
Leishmania major UDP-galactopyranose mutase 0.0041 0.0064 0.0278
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0156 0.0693
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0054 0.0231
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0196 0.0873
Schistosoma mansoni hypothetical protein 0.0321 0.0674 0.2159
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0108 0.021 0.0944
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0034
Loa Loa (eye worm) hypothetical protein 0.0272 0.0568 0.2552
Onchocerca volvulus 0.0012 0.0002 0.0007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0058 0.0245
Onchocerca volvulus 0.0067 0.0121 0.1144
Echinococcus granulosus defective proboscis extension response 0.0037 0.0055 0.0177
Schistosoma mansoni DNA polymerase eta 0.0136 0.0271 0.0867
Plasmodium vivax histone deacetylase 1, putative 0.0835 0.1795 0.1794
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0168 0.0745
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0022 0.0093
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0041 0.0064 0.0072
Echinococcus multilocularis BC026374 protein (S09 family) 0.0067 0.0121 0.0136
Plasmodium falciparum protoporphyrinogen oxidase 0.0041 0.0064 0.0063
Schistosoma mansoni hypothetical protein 0.05 0.1065 0.3412
Echinococcus multilocularis down syndrome cell adhesion 0.0012 0.0001 0.0001
Echinococcus multilocularis neuroglian 0.0049 0.0082 0.0092
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0156 0.0693
Schistosoma mansoni myosin-binding protein-related 0.0012 0.0001 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0058 0.0065
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0235 0.0486 0.1558
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0225 0.0223
Entamoeba histolytica acyl-CoA synthetase, putative 0.0144 0.0287 0.1531
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi glutaminase DH11.1 0.0287 0.06 0.2698
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0085 0.0378
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Schistosoma mansoni topbp1 0.006 0.0104 0.0334
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0041 0.0064 0.0063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0121 0.0388
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0156 0.0693
Schistosoma mansoni cell adhesion molecule 0.0048 0.0078 0.025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Schistosoma mansoni cell adhesion molecule 0.0012 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0045 0.0201
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.008 0.0256
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0185 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0017 0.003
Mycobacterium tuberculosis Conserved protein 0.0021 0.002 0.0035
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0072 0.0387
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.002 0.0077
Loa Loa (eye worm) DR-78 0.0024 0.0026 0.0115
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0042 0.0066 0.013
Brugia malayi Csnk2b protein 0.0036 0.0054 0.0239
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0107 0.0208 0.0418
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0021
Echinococcus multilocularis para nitrobenzyl esterase 0.0067 0.0121 0.0136
Loa Loa (eye worm) carboxylesterase 0.0067 0.0121 0.0542
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0835 0.1795 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.002 0.0095
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.002 0.0084
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0003 0.0001
Toxoplasma gondii thioredoxin reductase 0.0037 0.0056 0.0054
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0015 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0085 0.0378
Echinococcus granulosus titin 0.0012 0.0001 0.0003
Entamoeba histolytica recQ family helicase, putative 0.0021 0.002 0.0027
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0065 0.0116 0.051
Echinococcus multilocularis replication factor c subunit 1 0.006 0.0104 0.0117
Schistosoma mansoni amine oxidase 0.0041 0.0064 0.0206
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0015 0.0055
Onchocerca volvulus 0.0144 0.0287 0.272
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0087 0.0468
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0012 0.0001 0.0001
Loa Loa (eye worm) glutaminase 0.0287 0.06 0.2698
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Plasmodium vivax histone deacetylase, putative 0.0424 0.09 0.0898
Echinococcus multilocularis lachesin 0.0023 0.0024 0.0027
Echinococcus granulosus geminin 0.05 0.1065 0.3412
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Giardia lamblia Hypothetical protein 0.0022 0.0022 0.0106
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0017 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0054 0.0052
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0024 0.0103
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0049 0.0081 0.0079
Brugia malayi cell division control protein 2 homolog 0.0048 0.008 0.0356
Trypanosoma cruzi protein kinase, putative 0.0017 0.0012 0.0045
Entamoeba histolytica hypothetical protein 0.0037 0.0055 0.0224
Brugia malayi loechrig isoform VII 0.023 0.0477 0.2144
Brugia malayi Myosin head containing protein 0.0012 0.0002 0.0003
Entamoeba histolytica protein kinase, putative 0.019 0.0389 0.2101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0305 0.0639 0.2873
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0041 0.0064 0.0063
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.2266 0.4918 1
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.008 0.009
Treponema pallidum DNA ligase (lig) 0.006 0.0104 0.1115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0022 0.0106
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0098
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0144
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0371 0.1665
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.002 0.0085
Chlamydia trachomatis CBS domain-containing protein 0.0021 0.002 0.0017
Onchocerca volvulus 0.006 0.0104 0.0983
Brugia malayi Histone deacetylase family protein 0.103 0.2222 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0294 0.0616 0.0691
Plasmodium falciparum glutathione reductase 0.0037 0.0056 0.0054
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0116 0.0517
Echinococcus granulosus histone deacetylase 6 0.103 0.2222 0.7116
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.001 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0206 0.0423 0.1356
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0042 0.0066 0.013
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0185 0.0591
Loa Loa (eye worm) hypothetical protein 0.046 0.0978 0.4398
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0019 0.0015 0.0063
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0048 0.0206
Entamoeba histolytica protein kinase, putative 0.019 0.0389 0.2101
Schistosoma mansoni coup transcription factor 0.0051 0.0085 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0168 0.0745
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0109 0.0212 0.0953
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.002 0.0022
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0003 0.0001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0017 0.0184
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0144
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0054 0.022
Loa Loa (eye worm) histone deacetylase 0.103 0.2222 1
Toxoplasma gondii CBS domain-containing protein 0.0021 0.002 0.0018
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0042
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.002 0.0063
Schistosoma mansoni cell adhesion molecule 0.0023 0.0024 0.0076
Mycobacterium ulcerans cystathionine beta-synthase 0.0021 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0058 0.0065
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0431 0.0915 0.5091
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0181 0.0363
Loa Loa (eye worm) hypothetical protein 0.0044 0.0071 0.0317
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Entamoeba histolytica protein kinase , putative 0.017 0.0346 0.1862
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0014 0.0005 0.0012
Loa Loa (eye worm) Smad1 0.0016 0.001 0.0043
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0085 0.0272
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0017 0.0015
Schistosoma mansoni vesicular amine transporter 0.0037 0.0055 0.0177
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0017 0.0074
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0054 0.0231
Echinococcus multilocularis dual specificity 0.019 0.0389 0.0436
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.019 0.0389 0.174
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.004 0.0168
Leishmania major DNA polymerase eta, putative 0.0061 0.0107 0.0469
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0022 0.0108
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0021 0.002 0.0212
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.002 0.0063
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.001 0.0012
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.0587 0.2634
Mycobacterium ulcerans oxidoreductase 0.0041 0.0064 0.0062
Plasmodium falciparum thioredoxin reductase 0.0037 0.0056 0.0054
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0017 0.0019
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0087 0.0097
Loa Loa (eye worm) runx1 0.0055 0.0094 0.0421
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.001 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0085 0.0272
Trypanosoma brucei unspecified product 0.015 0.0301 0.1347
Schistosoma mansoni importin beta-1 0.003 0.004 0.0128
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Loa Loa (eye worm) hypothetical protein 0.0438 0.0931 0.4187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0085 0.0378
Onchocerca volvulus 0.0014 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0107 0.0208 0.0934
Schistosoma mansoni Smad4 0.0016 0.001 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0064 0.0278
Schistosoma mansoni DNA helicase recq1 0.0021 0.002 0.0063
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0021 0.002 0.0212
Brugia malayi nuclear hormone receptor 0.0024 0.0026 0.0115
Brugia malayi Prion-like- 0.0023 0.0024 0.0103
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0587 0.1256 0.4022
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0056
Echinococcus multilocularis neuroglian 0.0023 0.0024 0.0027
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0054 0.0052
Trypanosoma brucei SNF1-related protein kinases, putative 0.0049 0.0081 0.0352
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0835 0.1795 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.009 0.0088
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0245
Brugia malayi RE40412p 0.0014 0.0005 0.002
Echinococcus granulosus microtubule associated protein 2 0.1443 0.3122 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0121 0.0242
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0168 0.0745
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0085 0.0272
Loa Loa (eye worm) carboxylesterase 0.0067 0.0121 0.0542
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Brugia malayi Calcitonin receptor-like protein seb-1 0.0305 0.0639 0.2873
Entamoeba histolytica deoxycytidyl transferase, putative 0.0109 0.0212 0.1111
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0167 0.0535
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0011 0.0013
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.008 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0104 0.0568
Echinococcus granulosus Niemann Pick C1 protein 0.0294 0.0616 0.1973
Echinococcus multilocularis bloom syndrome protein 0.0021 0.002 0.0022
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0042 0.0066 0.0095
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0004 0.0002
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0116 0.0517
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.0587 0.2634
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0331 0.1479
Echinococcus multilocularis acetylcholinesterase 0.0399 0.0844 0.0947
Echinococcus multilocularis 0.0012 0.0001 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0181 0.0363
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0057 0.0182
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.002 0.0022
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.002 0.0077
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.023 0.0477 0.1528
Echinococcus granulosus twitchin 0.0054 0.0091 0.0292
Toxoplasma gondii NEK kinase 0.0022 0.0022 0.002
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0249 0.0517 0.1657
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0042
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.002 0.0077
Echinococcus granulosus BC026374 protein S09 family 0.0067 0.0121 0.0388
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0295
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0431 0.0915 0.5057
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.002 0.0085
Onchocerca volvulus 0.0024 0.0026 0.0243
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0101 0.045
Schistosoma mansoni septate junction protein 0.0023 0.0024 0.0076
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.002 0.0018 0.0017
Loa Loa (eye worm) histone deacetylase 7A 0.103 0.2222 1
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0026 0.0085
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Schistosoma mansoni histone deacetylase hda2 0.0424 0.09 0.2882
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0243 0.0505 0.1023
Echinococcus multilocularis histone deacetylase 6 0.103 0.2222 0.2493
Brugia malayi Patched related family protein 4 0.0012 0.0002 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0058 0.0259
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0321 0.0674 0.3031
Onchocerca volvulus 0.0159 0.032 0.3031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0104 0.0459
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0223 0.0714
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Toxoplasma gondii propionate-CoA ligase 0.0042 0.0066 0.0065
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0171 0.0346 0.111
Echinococcus multilocularis muscleblind protein 0.046 0.0978 0.1097
Brugia malayi Carboxylesterase family protein 0.0067 0.0121 0.0542
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0331 0.1479
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0058 0.0187
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0223 0.117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.0067
Echinococcus granulosus conserved hypothetical protein 0.0014 0.0005 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0022 0.0106
Brugia malayi jmjC domain containing protein 0.0065 0.0116 0.0519
Schistosoma mansoni hypothetical protein 0.0085 0.016 0.0513
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0048 0.0154
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0024 0.0027
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0382 0.0807 0.0805
Trypanosoma brucei unspecified product 0.0075 0.0139 0.0613
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.002 0.0063
Echinococcus granulosus titin 0.0012 0.0001 0.0003
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0798 0.1715 0.3484
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0032 0.0131
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0026 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002
Leishmania major histone deacetylase, putative 0.0835 0.1795 0.8077
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.023 0.0477 0.0535
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0021 0.002 0.0035
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0012 0.0001 0.0003
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0022 0.0093
Loa Loa (eye worm) TK protein kinase 0.0017 0.0011 0.0047
Schistosoma mansoni histone deacetylase 4 5 0.103 0.2222 0.7116
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0022 0.0087
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0164 0.0734
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0223 0.123
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0594 0.1269 0.5708
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0017 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0022 0.007
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0019 0.0015 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0156 0.0693
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0072 0.023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0045 0.0051
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0066 0.0287
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0066 0.013
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0466
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.002 0.0077
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.008 0.0356
Echinococcus granulosus histone deacetylase 8 0.0424 0.09 0.2882
Echinococcus granulosus histone deacetylase 7 0.103 0.2222 0.7116
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Brugia malayi RNA binding protein 0.0065 0.0116 0.0517
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0058 0.0101 0.0949
Schistosoma mansoni protein kinase 0.017 0.0346 0.1109
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0126 0.025 0.1123
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0022 0.0108
Brugia malayi serine/threonine kinase 12 0.017 0.0346 0.1555
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0104 0.0459
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0042 0.0066 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0085 0.0378
Toxoplasma gondii histone deacetylase HDAC3 0.0835 0.1795 0.1794
Entamoeba histolytica protein kinase, putative 0.017 0.0346 0.1862
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.002 0.0035
Schistosoma mansoni cpg binding protein 0.0061 0.0108 0.0346
Loa Loa (eye worm) hypothetical protein 0.0048 0.0078 0.0348
Brugia malayi ImpB/MucB/SamB family protein 0.0109 0.0212 0.0953
Brugia malayi DKFZp564C0469 protein 0.006 0.0104 0.0466
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0022 0.0086
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0022 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0085 0.0378
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0042 0.0066 0.013
Leishmania major acetyl-CoA synthetase, putative 0.0042 0.0066 0.0287
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0023 0.0072
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0085 0.0272
Plasmodium falciparum protein kinase 5 0.0048 0.008 0.0078
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0033 0.0037
Echinococcus granulosus hemicentin 1 0.0023 0.0024 0.0076
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0015 0.0066
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.002 0.0077
Onchocerca volvulus 0.0438 0.0931 0.8827
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0015 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0058 0.0251
Echinococcus multilocularis titin 0.0016 0.001 0.0012
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0065 0.0116 0.0567
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0002
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0022 0.002
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0017 0.002
Brugia malayi nuclear receptor NHR-67 0.0024 0.0026 0.0115
Loa Loa (eye worm) hypothetical protein 0.0107 0.0208 0.0934
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0042
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.008 0.0256
Onchocerca volvulus 0.0051 0.0085 0.0798
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0058 0.0187
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0085 0.0272
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0017 0.0067
Onchocerca volvulus 0.0067 0.0121 0.1144
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0014 0.0005 0.0004
Plasmodium falciparum histone deacetylase, putative 0.103 0.2222 0.2221
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0041 0.0064 0.0062
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0017 0.0056
Echinococcus multilocularis muscleblind protein 1 0.046 0.0978 0.1097
Loa Loa (eye worm) hypothetical protein 0.0044 0.0071 0.0317
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0042 0.004
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.009 0.04
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0042 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0008 0.0009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0144 0.0287 0.0547
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.002 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0119 0.065
Trypanosoma brucei histone deacetylase 2 0.0424 0.09 0.4043
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0066 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0081 0.0258
Entamoeba histolytica Flap nuclease, putative 0.0053 0.009 0.042
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Trichomonas vaginalis spcc417.12 protein, putative 0.0067 0.0121 0.0662
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0024 0.0103
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0136 0.0271 0.1216
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0055 0.0175
Trypanosoma cruzi aurora B kinase, putative 0.017 0.0346 0.1548
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1251 0.1249
Schistosoma mansoni zinc finger protein 0.0024 0.0026 0.0085
Echinococcus granulosus tyrosine protein kinase otk 0.0023 0.0024 0.0076
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0042 0.0217
Plasmodium vivax acyl-CoA synthetase, putative 0.0107 0.0208 0.0207
Loa Loa (eye worm) hypothetical protein 0.0067 0.0121 0.0542
Loa Loa (eye worm) hypothetical protein 0.0096 0.0185 0.0827
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0042 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0495 0.1584
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.001 0.0033
Echinococcus granulosus neuroglian 0.0023 0.0024 0.0076
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.002 0.0077
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0022 0.0086
Onchocerca volvulus 0.01 0.0192 0.1815
Schistosoma mansoni rotamase 0.0066 0.0119 0.0381
Brugia malayi Flap endonuclease-1 0.0053 0.009 0.04
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0054 0.0231
Plasmodium vivax JmjC domain containing protein 0.0016 0.001 0.0009
Schistosoma mansoni cpg binding protein 0.0061 0.0108 0.0346
Echinococcus granulosus histone deacetylase 6 0.1049 0.2262 0.7246
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.009 0.0392
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0087 0.0468
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0054 0.0286
Plasmodium falciparum flap endonuclease 1 0.0053 0.009 0.0088
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.001 0.0033
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0081 0.0352
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Entamoeba histolytica hypothetical protein 0.006 0.0104 0.0503
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0085 0.0798
Schistosoma mansoni titin 0.0012 0.0001 0.0003
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0048 0.0047
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0049 0.0081 0.037
Schistosoma mansoni ran 0.0022 0.0023 0.0072
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0054 0.0052
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0112 0.0218 0.098
Loa Loa (eye worm) hypothetical protein 0.0107 0.0208 0.0934
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.002 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus Protein patched homolog 0.0012 0.0002 0.0007
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0042 0.0066 0.0064
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0109 0.0212 0.0681
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0021 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0285
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0053 0.0104
Echinococcus granulosus contactin 0.0023 0.0024 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0005 0.0004
Leishmania major hypothetical protein, conserved 0.0019 0.0015 0.0055
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0015 0.0013
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.001 0.0034
Leishmania major chloride channel protein, putative 0.0021 0.002 0.0077
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0024 0.0027
Schistosoma mansoni nuclear receptor 0.0024 0.0026 0.0085
Echinococcus multilocularis dna polymerase kappa 0.0163 0.0331 0.0371
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0042 0.004
Echinococcus multilocularis histone deacetylase 7 0.103 0.2222 0.2493
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0042 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0022 0.0093
Echinococcus multilocularis histone deacetylase 3 0.0835 0.1795 0.2014
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0331 0.1479
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Echinococcus multilocularis roundabout 2 0.0023 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0085 0.0378
Schistosoma mansoni histone deacetylase hda2 0.1049 0.2262 0.7246
Schistosoma mansoni hemicentin 0.0012 0.0001 0.0003
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 0.0363 0.3442
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0166 0.0739
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0015 0.0013
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0048 0.0206
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0064 0.0278
Echinococcus granulosus cyclin dependent kinase 0.0048 0.008 0.0256
Loa Loa (eye worm) AUR protein kinase 0.017 0.0346 0.1555
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0085
Chlamydia trachomatis Mg++ transporter 0.0021 0.002 0.0017
Trypanosoma brucei protein kinase, putative 0.0051 0.0087 0.0378
Brugia malayi nuclear receptor RXR 0.0024 0.0026 0.0115
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0109 0.0212 0.0238
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0042
Brugia malayi jmjC domain containing protein 0.0062 0.0109 0.0487
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.008 0.0348
Brugia malayi hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0067 0.0121 0.1144
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0195 0.0392
Brugia malayi N-terminal motif family protein 0.0178 0.0363 0.1632
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0085 0.0378
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.002 0.0095
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.023 0.0477 0.2647
Trichomonas vaginalis histone deacetylase, putative 0.0835 0.1795 1
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0081 0.0436
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0072 0.007
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0022 0.0106
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0048 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.001 0.0033
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.009 0.0392
Loa Loa (eye worm) hypothetical protein 0.0023 0.0024 0.0103
Schistosoma mansoni histone deacetylase 1 2 3 0.0424 0.09 0.2882
Plasmodium vivax glutathione reductase, putative 0.0037 0.0056 0.0054
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.001 0.0034
Loa Loa (eye worm) hypothetical protein 0.046 0.0978 0.4398
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0048 0.0047
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0087 0.0164 0.0734
Toxoplasma gondii aurora kinase 0.017 0.0346 0.0345
Loa Loa (eye worm) patched family protein 0.0012 0.0002 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0032 0.0131
Brugia malayi 6-phosphofructokinase 0.0114 0.0223 0.1001
Brugia malayi Carboxylesterase family protein 0.0067 0.0121 0.0542
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0085 0.0378
Schistosoma mansoni hypothetical protein 0.0087 0.0164 0.0525
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0026 0.0085
Trichomonas vaginalis antibiotic synthetase, putative 0.0042 0.0066 0.0355
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0066 0.0295
Trypanosoma brucei AIR9-like protein 0.0014 0.0005 0.0012
Brugia malayi hypothetical protein 0.0027 0.0033 0.0144
Schistosoma mansoni hypothetical protein 0.05 0.1065 0.3412
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0026 0.003
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0171 0.0346 0.0389
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0167 0.0748
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0144 0.0287 0.0547
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0042 0.0066 0.013
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0116 0.0371
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0033 0.0144
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0382 0.0807 0.0805
Echinococcus granulosus acetylcholinesterase 0.0399 0.0844 0.2704
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.016 0.0287
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0115
Onchocerca volvulus 0.0024 0.0026 0.0243
Loa Loa (eye worm) hypothetical protein 0.0107 0.0208 0.0934
Leishmania major histone deacetylase, putative 0.103 0.2222 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0085 0.0095
Brugia malayi Patched family protein 0.0012 0.0002 0.0003
Brugia malayi Carboxylesterase family protein 0.0067 0.0121 0.0542
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0116 0.0372
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0121 0.0388
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0042 0.0039
Trypanosoma brucei histone deacetylase 3 0.103 0.2222 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0026 0.0085
Schistosoma mansoni hypothetical protein 0.0208 0.0429 0.1373
Brugia malayi Protein kinase domain containing protein 0.019 0.0389 0.1747
Schistosoma mansoni chloride channel protein 0.0021 0.002 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0371 0.0416
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0239 0.0495 0.0555
Onchocerca volvulus 0.0067 0.0121 0.1144
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.002 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0002

Activities

Activity type Activity value Assay description Source Reference
F (ADMET) ND 0 % Bioavailability in rat using combiPK assay (dose 1 mg/kg i.v.) ChEMBL. 15911249
F (ADMET) ND 0 % Bioavailability in rat using combiPK assay (dose 2 mg/kg p.o.) ChEMBL. 15911249
Ki (binding) = 32 nM In vitro inhibitory activity against tryptase ChEMBL. 15911249
Ki (binding) = 32 nM In vitro inhibitory activity against tryptase ChEMBL. 15911249

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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