Detailed information for compound 332336

Basic information

Technical information
  • TDR Targets ID: 332336
  • Name: 3-[[4-[4-(3-chloroanilino)-1,3,5-triazin-2-yl ]pyridin-2-yl]amino]propan-1-ol
  • MW: 356.809 | Formula: C17H17ClN6O
  • H donors: 3 H acceptors: 5 LogP: 3.61 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCCNc1nccc(c1)c1ncnc(n1)Nc1cccc(c1)Cl
  • InChi: 1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24)
  • InChiKey: AAYPLLWGPJQWCC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[[4-[4-(3-chloroanilino)-1,3,5-triazin-2-yl]-2-pyridyl]amino]propan-1-ol
  • 3-[[4-[4-(3-chloroanilino)-1,3,5-triazin-2-yl]-2-pyridyl]amino]-1-propanol
  • 3-[[4-[4-[(3-chlorophenyl)amino]-1,3,5-triazin-2-yl]pyridin-2-yl]amino]propan-1-ol
  • 3-[[4-[4-(3-chloroanilino)-s-triazin-2-yl]-2-pyridyl]amino]propan-1-ol
  • 3-[[4-[4-[(3-chlorophenyl)amino]-1,3,5-triazin-2-yl]-2-pyridyl]amino]propan-1-ol
  • 3-[[4-[4-[(3-chlorophenyl)amino]-s-triazin-2-yl]-2-pyridyl]amino]propan-1-ol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin B1 References
Homo sapiens cyclin D3 Starlite/ChEMBL References
Homo sapiens casein kinase 2, beta polypeptide Starlite/ChEMBL References
Homo sapiens casein kinase 2, alpha prime polypeptide References
Homo sapiens casein kinase 1, gamma 2 References
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 5 Starlite/ChEMBL References
Homo sapiens v-akt murine thymoma viral oncogene homolog 2 Starlite/ChEMBL References
Homo sapiens platelet-derived growth factor receptor, beta polypeptide References
Homo sapiens cyclin A2 References
Homo sapiens cyclin A1 Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL References
Homo sapiens casein kinase 1, delta References
Homo sapiens cyclin-dependent kinase 7 References
Homo sapiens casein kinase 1, epsilon References
Homo sapiens casein kinase 2, alpha 1 polypeptide References
Homo sapiens cyclin-dependent kinase 5, regulatory subunit 1 (p35) References
Homo sapiens platelet-derived growth factor receptor, alpha polypeptide Starlite/ChEMBL References
Homo sapiens casein kinase 1, gamma 1 References
Homo sapiens cyclin-dependent kinase 6 References
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References
Homo sapiens fibroblast growth factor receptor 2 Starlite/ChEMBL References
Homo sapiens cyclin D1 Starlite/ChEMBL References
Homo sapiens cyclin B3 Starlite/ChEMBL References
Homo sapiens epidermal growth factor receptor Starlite/ChEMBL References
Homo sapiens cyclin B2 Starlite/ChEMBL References
Homo sapiens casein kinase 1, alpha 1 Starlite/ChEMBL References
Homo sapiens cyclin H Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 4 References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Candida albicans hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) cyclin domain-containing protein Get druggable targets OG5_129254 All targets in OG5_129254
Schistosoma japonicum ko:K03097 casein kinase 2, alpha polypeptide, putative Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128597 All targets in OG5_128597
Plasmodium vivax unspecified product Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis cyclin dependent kinase 6 Get druggable targets OG5_133618 All targets in OG5_133618
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Trypanosoma brucei Casein kinase II Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) Csnk2b protein Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus casein kinase ii subunit alpha Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum ko:K05085 receptor tyrosine-protein kinase erbB-4, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Theileria parva casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K02091 cyclin-dependent kinase 6, putative Get druggable targets OG5_133618 All targets in OG5_133618
Toxoplasma gondii CMGC kinase, CK2 family Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Schistosoma japonicum expressed protein Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Trypanosoma congolense casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania mexicana CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_128769 All targets in OG5_128769
Babesia bovis casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans cyclin Get druggable targets OG5_129254 All targets in OG5_129254
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Casein kinase I isoform delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128769 All targets in OG5_128769
Plasmodium knowlesi casein kinase 2, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans second casein kinase I-like orf Get druggable targets OG5_128520 All targets in OG5_128520
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi Csnk2b protein Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium yoelii Protein kinase domain Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii casein kinase ii regulatory subunit protein Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans Casein kinase II, regulatory (beta-prime) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Giardia lamblia Kinase, CK1 Casein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Onchocerca volvulus Casein kinase II subunit beta homolog Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum IPR002155,Thiolase,domain-containing Get druggable targets OG5_134175 All targets in OG5_134175
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Leishmania major protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma congolense casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131242 All targets in OG5_131242
Echinococcus granulosus cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Theileria parva casein kinase II, alpha chain Get druggable targets OG5_126901 All targets in OG5_126901
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CK2 protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Toxoplasma gondii ck2 beta subunit Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Plasmodium berghei casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium knowlesi casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium knowlesi casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania braziliensis protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans likely B-type cyclin similar to S. cerevisiae CLB4 (YLR210W) and CLB3 (YDL155W) involved in G1/S transition Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131242 All targets in OG5_131242
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus cyclin dependent kinase 6 Get druggable targets OG5_133618 All targets in OG5_133618
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 7 Get druggable targets OG5_129224 All targets in OG5_129224
Echinococcus granulosus casein kinase ii subunit beta Get druggable targets OG5_126846 All targets in OG5_126846
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium yoelii casein kinase ii beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis casein kinase ii subunit alpha Get druggable targets OG5_126901 All targets in OG5_126901
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans similar to headcase protein Get druggable targets OG5_128520 All targets in OG5_128520
Leishmania donovani casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum cyclin domain protein, possible cyclin H Get druggable targets OG5_129254 All targets in OG5_129254
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus G1:S specific cyclin D1 Get druggable targets OG5_131242 All targets in OG5_131242
Echinococcus granulosus melanoma receptor tyrosine protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Plasmodium vivax casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium knowlesi casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_128520 All targets in OG5_128520
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126901 All targets in OG5_126901
Entamoeba histolytica casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni cyclin-dependent kinase 5 activator Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K10151 cyclin D2, putative Get druggable targets OG5_131242 All targets in OG5_131242
Trypanosoma cruzi CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania mexicana casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum Fibroblast growth factor receptor precursor, putative Get druggable targets OG5_128769 All targets in OG5_128769
Trypanosoma congolense mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania infantum CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum IPR000494,EGF receptor, L domain,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis cyclin H, putative Get druggable targets OG5_129254 All targets in OG5_129254
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Brugia malayi Casein kinase II, alpha chain Get druggable targets OG5_126901 All targets in OG5_126901
Theileria parva casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) TK/EGFR protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium falciparum casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) TK protein kinase Get druggable targets OG5_128769 All targets in OG5_128769
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_128520 All targets in OG5_128520
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-4 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Brugia malayi cyclin-dependent kinase 7 homolog Get druggable targets OG5_129224 All targets in OG5_129224
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Trypanosoma cruzi Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Candida albicans casein kinase I-like orf Get druggable targets OG5_128520 All targets in OG5_128520
Schistosoma japonicum expressed protein Get druggable targets OG5_129224 All targets in OG5_129224
Schistosoma japonicum ko:K03115 casein kinase 2, beta polypeptide, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei gambiense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei gambiense casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_129254 All targets in OG5_129254
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania infantum protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Casein kinase II alpha' subunit Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Cryptosporidium parvum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis cyclin A, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Theileria parva casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 Get druggable targets OG5_133447 All targets in OG5_133447
Trypanosoma congolense Cyclin, N-terminal domain/Cyclin, C-terminal domain containing protein, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis fibroblast growth factor receptor 4 Get druggable targets OG5_128769 All targets in OG5_128769
Echinococcus multilocularis cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_129254 All targets in OG5_129254
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Neospora caninum YOR039Wp-like protein, related Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Schistosoma japonicum Cyclin-dependent kinase 5 activator 2 precursor, putative Get druggable targets OG5_133447 All targets in OG5_133447
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A Get druggable targets OG5_128769 All targets in OG5_128769
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Onchocerca volvulus Casein kinase II subunit beta homolog Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Neospora caninum casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis casein kinase I gamma Get druggable targets OG5_128520 All targets in OG5_128520
Babesia bovis casein kinase II beta 4 subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Loa Loa (eye worm) cyclin domain-containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K03115 casein kinase 2, beta polypeptide, putative Get druggable targets OG5_126846 All targets in OG5_126846
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans similar to headcase protein Get druggable targets OG5_128520 All targets in OG5_128520
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium berghei casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum ko:K08958 casein kinase 1, gamma, putative Get druggable targets OG5_128520 All targets in OG5_128520
Trypanosoma cruzi Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum casein kinase II, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum Tyrosine-protein kinase transforming protein erbB, putative Get druggable targets OG5_128597 All targets in OG5_128597
Cryptosporidium hominis mitotic cyclin-CYC2 Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus multilocularis casein kinase ii subunit beta Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum hypothetical protein Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans Serine-threonine kinase, subunit of RNA Pol TFIIK. Get druggable targets OG5_129224 All targets in OG5_129224
Candida albicans Casein kinase II, regulatory (beta) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis G1:S specific cyclin D1 Get druggable targets OG5_131242 All targets in OG5_131242
Plasmodium yoelii casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus granulosus fibroblast growth factor receptor 4 Get druggable targets OG5_128769 All targets in OG5_128769
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis protein kinase domain Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium vivax casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Plasmodium yoelii protein kinase Ck2-beta Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans second casein kinase I-like orf Get druggable targets OG5_128520 All targets in OG5_128520
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_134175 All targets in OG5_134175
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Babesia bovis casein kinase II, alpha chain (CK II) Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Leishmania donovani cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum putative casein kinase II regulatory subunit; besthit Pf 23508244 Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania braziliensis casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi casein kinase 1, delta Get druggable targets OG5_126780 All targets in OG5_126780
Giardia lamblia Kinase, CMGC CK2 Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) protein kinase domain-containing protein Get druggable targets OG5_128520 All targets in OG5_128520
Trypanosoma brucei gambiense cyclin 6,mitotic cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Giardia lamblia G2/mitotic-specific cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania infantum casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum IPR000719,Protein kinase;IPR011009,Protein kinase-like,domain-containing Get druggable targets OG5_128520 All targets in OG5_128520
Schistosoma japonicum ko:K08959 casein kinase 1, delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans cyclin Get druggable targets OG5_129254 All targets in OG5_129254
Leishmania mexicana protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus cyclin dependent kinase 7 Get druggable targets OG5_129224 All targets in OG5_129224
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Entamoeba histolytica hypothetical protein Get druggable targets OG5_129254 All targets in OG5_129254
Schistosoma japonicum IPR006212,Furin-like repeat;IPR009030,Growth factor, receptor,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus cyclin dependent kinase 5 activator 1 Get druggable targets OG5_133447 All targets in OG5_133447
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis Get druggable targets OG5_128597 All targets in OG5_128597
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02218 casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica casein kinase, putative Get druggable targets OG5_126901 All targets in OG5_126901
Giardia lamblia Casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium berghei casein kinase 2, alpha subunit Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Cryptosporidium hominis protein kinase Ck2-beta Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Onchocerca volvulus Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans Casein kinase II, regulatory (beta) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans Casein kinase II alpha' subunit Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni cyclin d Get druggable targets OG5_131242 All targets in OG5_131242
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium falciparum casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Serine-threonine kinase, subunit of RNA Pol TFIIK. Get druggable targets OG5_129224 All targets in OG5_129224
Cryptosporidium parvum putative protein kinase CK2 regulatory subunit CK2B1 Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) casein kinase Get druggable targets OG5_128520 All targets in OG5_128520
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-2 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Babesia bovis protein kinase CK2 regulatory subunit CK2B1 Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum IPR002048,Calcium-binding EF-hand;IPR001245,Tyrosine protein kinase;IPR000719,Protein kinase;IPR011009,Protein kinase-like,domai Get druggable targets OG5_128769 All targets in OG5_128769
Candida albicans hypothetical protein Get druggable targets OG5_128520 All targets in OG5_128520
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium falciparum casein kinase 1 Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Candida albicans likely protein kinase similar to S. cerevisiae CKA1 (YIL035C) alpha subunit of protein kinase 2, aka casein kinase II Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium vivax casein kinase 2, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni casein kinase II beta subunit Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium falciparum casein kinase 2, alpha subunit Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans Casein kinase II, regulatory (beta-prime) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_133618 All targets in OG5_133618
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Cryptosporidium hominis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_131242 All targets in OG5_131242
Leishmania infantum casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi Furin-like cysteine rich region family protein Get druggable targets OG5_128597 All targets in OG5_128597
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum AFL091Wp, related Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus casein kinase I gamma Get druggable targets OG5_128520 All targets in OG5_128520
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Leishmania braziliensis cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus basic fibroblast growth factor receptor 1 A Get druggable targets OG5_128769 All targets in OG5_128769
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium vivax casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 5 260 aa 307 aa 28.3 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 7 346 aa 311 aa 32.5 %
Plasmodium falciparum cyclin cyclin H 270 aa 253 aa 22.1 %
Trypanosoma cruzi casein kinase II, alpha chain, putative casein kinase 2, alpha prime polypeptide 350 aa 319 aa 50.2 %
Trypanosoma cruzi casein kinase II, alpha chain, putative casein kinase 2, alpha 1 polypeptide 391 aa 316 aa 51.3 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 6 326 aa 314 aa 31.2 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 4 303 aa 312 aa 29.8 %
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative cyclin D3 211 aa 192 aa 25.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Brugia malayi Protein kinase domain containing protein casein kinase 1, alpha 1 365 aa 307 aa 24.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax casein kinase 1, putative 0.0144 0.4194 0.8214
Echinococcus multilocularis 0.0056 0.1111 0.1111
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0172 0.0205
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Loa Loa (eye worm) TK protein kinase 0.018 0.5489 0.5489
Plasmodium falciparum protein kinase 5 0.011 0.3027 0.583
Trypanosoma brucei mitotic cyclin 6 0.0262 0.8359 1
Echinococcus granulosus cyclin k 0.004 0.0562 0.0562
Giardia lamblia Hypothetical protein 0.015 0.4413 0.494
Loa Loa (eye worm) AGC/AKT protein kinase 0.0057 0.1158 0.1158
Schistosoma mansoni serine/threonine protein kinase 0.011 0.3027 0.3027
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.011 0.3027 0.583
Trypanosoma cruzi CYC2-like cyclin, putative 0.0262 0.8359 1
Entamoeba histolytica protein kinase, putative 0.0057 0.1158 0.1386
Trichomonas vaginalis cyclins, putative 0.004 0.0562 0.0672
Schistosoma mansoni g1/s-specific cyclin C 0.0122 0.3428 0.3428
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0169 0.5069 0.5069
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Trypanosoma cruzi cyclin 9, putative 0.004 0.0562 0.0477
Entamoeba histolytica casein kinase, putative 0.0144 0.4194 0.5018
Loa Loa (eye worm) cyclin domain-containing protein 0.0284 0.9128 0.9128
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.3027 0.3488
Echinococcus granulosus cyclin dependent kinase 6 0.0209 0.6481 0.6481
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0144 0.4194 0.4914
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0033 0.0313 0.0313
Trichomonas vaginalis cyclin H, putative 0.0077 0.184 0.2202
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0708 0.0846
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Loa Loa (eye worm) hypothetical protein 0.0045 0.0738 0.0738
Echinococcus granulosus casein kinase ii subunit alpha 0.0169 0.5069 0.5069
Echinococcus granulosus aldo keto reductase 0.01 0.2664 0.2664
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0172 0.0205
Echinococcus granulosus hypothetical protein 0.01 0.2664 0.2664
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0063 0.1366 0.1366
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0068 0.1549 0.1682
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.01 0.2664 0.3187
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Trypanosoma cruzi casein kinase, putative 0.0144 0.4194 0.4914
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.004 0.0567 0.0808
Trichomonas vaginalis CK1 family protein kinase 0.0144 0.4194 0.5018
Echinococcus granulosus mitogen activated protein kinase 0.0068 0.1549 0.1549
Echinococcus multilocularis roundabout 2 0.0045 0.0738 0.0738
Brugia malayi cyclin-dependent kinase 7 homolog 0.01 0.2653 0.2907
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Brugia malayi CXXC zinc finger family protein 0.0028 0.0142 0.0156
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0068 0.1549 0.2812
Trypanosoma brucei casein kinase I, isoform 2 0.0144 0.4194 0.4914
Echinococcus granulosus casein kinase i 0.0144 0.4194 0.4194
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Loa Loa (eye worm) TK/EGFR protein kinase 0.0186 0.5666 0.5666
Loa Loa (eye worm) hypothetical protein 0.01 0.2664 0.2664
Entamoeba histolytica cyclin, domain containing protein 0.004 0.0562 0.0672
Entamoeba histolytica cyclin, putative 0.015 0.4413 0.528
Entamoeba histolytica aldose reductase, putative 0.01 0.2664 0.3187
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0169 0.5069 1
Loa Loa (eye worm) CYL-1 protein 0.004 0.0562 0.0562
Loa Loa (eye worm) Csnk2b protein 0.0044 0.0708 0.0708
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.01 0.2664 0.2918
Entamoeba histolytica hypothetical protein 0.0077 0.184 0.2202
Echinococcus granulosus serine threonine protein kinase nrc 0.004 0.0567 0.0567
Echinococcus multilocularis cyclin dependent kinase 0.011 0.3027 0.3027
Trypanosoma cruzi casein kinase, putative 0.0144 0.4194 0.4914
Entamoeba histolytica cyclin C, putative 0.004 0.0562 0.0672
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.011 0.3027 0.3488
Toxoplasma gondii casein kinase I 0.0144 0.4194 0.8214
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.01 0.2664 0.2918
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Schistosoma mansoni tyrosine kinase 0.0063 0.1366 0.1366
Loa Loa (eye worm) oxidoreductase 0.01 0.2664 0.2664
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.01 0.2664 1
Trichomonas vaginalis cyclin B, putative 0.0262 0.8359 1
Brugia malayi hypothetical protein 0.004 0.0562 0.0616
Brugia malayi Cyclin, N-terminal domain containing protein 0.0222 0.6956 0.762
Trypanosoma cruzi mitotic cyclin, putative 0.004 0.0562 0.0477
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0068 0.1549 0.1682
Schistosoma mansoni tyrosine kinase 0.0096 0.2515 0.2515
Toxoplasma gondii cyclin dependent kinase binding protein 0.004 0.0562 0.0797
Echinococcus multilocularis rac serine:threonine kinase 0.004 0.0567 0.0567
Schistosoma mansoni aldo-keto reductase 0.01 0.2664 0.2664
Echinococcus granulosus cyclin b3 0.015 0.4413 0.4413
Trichomonas vaginalis cyclin A, putative 0.0262 0.8359 1
Schistosoma mansoni Cyclin fold protein 0.004 0.0562 0.0562
Echinococcus multilocularis casein kinase I alpha 0.0144 0.4194 0.4194
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Echinococcus multilocularis cyclin dependent kinase 7 0.01 0.2653 0.2653
Brugia malayi Cyclin, N-terminal domain containing protein 0.0198 0.6113 0.6698
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Echinococcus multilocularis aldo keto reductase 0.01 0.2664 0.2664
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0203 0.6276 0.6276
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Trypanosoma cruzi aldo/keto reductase, putative 0.01 0.2664 0.3044
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.1549 0.1853
Entamoeba histolytica cell division protein kinase 2, putative 0.011 0.3027 0.3621
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.004 0.0567 0.0567
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0144 0.4194 0.4194
Schistosoma mansoni cyclins 0.015 0.4413 0.4413
Entamoeba histolytica protein kinase, putative 0.0057 0.1158 0.1386
Schistosoma mansoni potassium channel beta 0.0029 0.0172 0.0172
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0284 0.9128 0.9128
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0144 0.4194 0.4194
Trichomonas vaginalis CK1 family protein kinase 0.0144 0.4194 0.5018
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0063 0.1366 0.1366
Echinococcus granulosus nervana 2 0.0033 0.0313 0.0313
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.1549 0.1549
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.004 0.0562 0.0797
Loa Loa (eye worm) oxidoreductase 0.01 0.2664 0.2664
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.004 0.0567 0.0567
Echinococcus granulosus roundabout 2 0.0045 0.0738 0.0738
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0144 0.4194 0.4194
Echinococcus multilocularis mitogen activated protein kinase 3 0.0068 0.1549 0.1549
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0029 0.0172 0.0172
Echinococcus multilocularis nervana 2 0.0033 0.0313 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0562 0.0672
Schistosoma mansoni protein kinase 0.0169 0.5069 0.5069
Schistosoma mansoni serine/threonine-protein kinase 0.004 0.0567 0.0567
Onchocerca volvulus 0.004 0.0562 0.051
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.1549 0.1853
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0068 0.1549 0.1682
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Echinococcus multilocularis casein kinase I delta 0.0144 0.4194 0.4194
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.011 0.3027 0.3488
Trypanosoma cruzi aldo-keto reductase 0.01 0.2664 0.3044
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.004 0.0562 0.0562
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0044 0.0708 0.1095
Trypanosoma brucei cdc2-related kinase 3 0.011 0.3027 0.3488
Trypanosoma cruzi cyclin 6, putative 0.0262 0.8359 1
Giardia lamblia Kinase, CK1 Casein kinase 0.0144 0.4194 0.4659
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.01 0.2664 0.3044
Echinococcus granulosus cyclins 0.015 0.4413 0.4413
Trichomonas vaginalis cyclin D, putative 0.015 0.4413 0.528
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0068 0.1549 0.1682
Toxoplasma gondii hypothetical protein 0.004 0.0562 0.0797
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Echinococcus granulosus cyclin A3 4 0.004 0.0562 0.0562
Mycobacterium tuberculosis Probable oxidoreductase 0.01 0.2664 1
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Schistosoma mansoni tyrosine kinase 0.0096 0.2515 0.2515
Giardia lamblia G2/mitotic-specific cyclin B 0.0262 0.8359 1
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.4194 0.4194
Loa Loa (eye worm) hypothetical protein 0.0148 0.4347 0.4347
Schistosoma mansoni cyclin d 0.0222 0.6956 0.6956
Entamoeba histolytica casein kinase 1, putative 0.0144 0.4194 0.5018
Loa Loa (eye worm) hypothetical protein 0.0262 0.8359 0.8359
Echinococcus granulosus cyclins 0.015 0.4413 0.4413
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0165 0.4952 0.4952
Schistosoma mansoni tyrosine kinase 0.0063 0.1366 0.1366
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0562 0.0562
Echinococcus granulosus cyclin G2 0.004 0.0562 0.0562
Trichomonas vaginalis CMGC family protein kinase 0.011 0.3027 0.3621
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Brugia malayi Csnk2b protein 0.0044 0.0708 0.0775
Schistosoma mansoni protein kinase 0.0144 0.4194 0.4194
Giardia lamblia Kinase, CMGC CDK 0.011 0.3027 0.3162
Echinococcus granulosus cyclin 0.0122 0.3428 0.3428
Trichomonas vaginalis CMGC family protein kinase 0.011 0.3027 0.3621
Trichomonas vaginalis cyclin B, putative 0.004 0.0562 0.0672
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.1549 0.1853
Echinococcus granulosus cyclin t1 0.004 0.0562 0.0562
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.011 0.3027 0.3027
Schistosoma mansoni nephrin 0.0038 0.0481 0.0481
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0172 0.0205
Echinococcus multilocularis aldo keto reductase 0.01 0.2664 0.2664
Giardia lamblia Kinase, CMGC CK2 0.0169 0.5069 0.5781
Loa Loa (eye worm) oxidoreductase 0.01 0.2664 0.2664
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0562 0.0672
Echinococcus granulosus serine/threonine protein kinase 0.004 0.0567 0.0567
Schistosoma mansoni cpg binding protein 0.003 0.0199 0.0199
Echinococcus granulosus cyclin dependent kinase 5 0.011 0.3027 0.3027
Schistosoma mansoni tyrosine kinase 0.0096 0.2515 0.2515
Leishmania major aldo-keto reductase-like protein 0.01 0.2664 0.3044
Onchocerca volvulus 0.01 0.2664 0.3069
Schistosoma mansoni cpg binding protein 0.0028 0.0142 0.0142
Giardia lamblia Kinase, AGC PKA 0.004 0.0567 0.0007
Plasmodium falciparum casein kinase 1 0.0144 0.4194 0.8214
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.004 0.0562 0.0562
Echinococcus multilocularis cyclin y 0.004 0.0562 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0562 0.0672
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0708 0.0846
Trichomonas vaginalis cyclin B, putative 0.0262 0.8359 1
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.3027 0.3488
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Echinococcus multilocularis casein kinase ii subunit beta 0.0044 0.0708 0.0708
Echinococcus granulosus cyclin B 0.0262 0.8359 0.8359
Trichomonas vaginalis conserved hypothetical protein 0.015 0.4413 0.528
Echinococcus granulosus casein kinase I delta 0.0144 0.4194 0.4194
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0562 0.0562
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.004 0.0567 0.0808
Echinococcus granulosus cyclin y 0.004 0.0562 0.0562
Echinococcus multilocularis insulin receptor 0.0063 0.1366 0.1366
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.5489 0.6014
Echinococcus multilocularis Cyclin L1 0.004 0.0562 0.0562
Echinococcus granulosus Glutaredoxin protein 5 0.0033 0.0313 0.0313
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0562 0.0562
Trichomonas vaginalis cyclin B, putative 0.0262 0.8359 1
Plasmodium vivax cyclin 4, putative 0.004 0.0562 0.0797
Echinococcus granulosus voltage gated potassium channel subunit 0.0029 0.0172 0.0172
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0708 0.0846
Brugia malayi Cyclin C 0.0122 0.3428 0.3756
Schistosoma mansoni tyrosine kinase 0.0029 0.0176 0.0176
Echinococcus multilocularis nervana 2 0.0033 0.0313 0.0313
Trichomonas vaginalis CK1 family protein kinase 0.0144 0.4194 0.5018
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0044 0.0708 0.0655
Trichomonas vaginalis aldo/keto reductase, putative 0.01 0.2664 0.3187
Giardia lamblia Kinase, CMGC CDK 0.011 0.3027 0.3162
Schistosoma mansoni tyrosine kinase 0.0186 0.5666 0.5666
Echinococcus granulosus twitchin 0.0045 0.0735 0.0735
Brugia malayi Protein kinase domain containing protein 0.0057 0.1158 0.1269
Brugia malayi NADH-dependent xylose reductase 0.0029 0.0172 0.0188
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.003 0.0201 0.0201
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0122 0.3428 0.3428
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Entamoeba histolytica protein kinase, putative 0.0057 0.1158 0.1386
Toxoplasma gondii CMGC kinase, CK2 family 0.0169 0.5069 1
Entamoeba histolytica hypothetical protein 0.004 0.0562 0.0672
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0262 0.8359 1
Toxoplasma gondii aldose reductase, putative 0.01 0.2664 0.5089
Schistosoma mansoni hypothetical protein 0.004 0.0562 0.0562
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0562 0.0616
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0284 0.9128 0.9128
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0029 0.0172 0.0188
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0033 0.0313 0.0313
Echinococcus granulosus cpg binding protein 0.003 0.0199 0.0199
Plasmodium vivax casein kinase II beta chain, putative 0.0044 0.0708 0.1095
Onchocerca volvulus 0.0262 0.8359 1
Onchocerca volvulus 0.01 0.2664 0.3069
Loa Loa (eye worm) hypothetical protein 0.004 0.0562 0.0562
Echinococcus multilocularis epidermal growth factor receptor 0.0186 0.5666 0.5666
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Echinococcus multilocularis cyclin 0.0122 0.3428 0.3428
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0562 0.0616
Trypanosoma brucei aldo-keto reductase, putative 0.01 0.2664 0.3044
Schistosoma mansoni cyclin l 0.004 0.0562 0.0562
Brugia malayi cyclin fold protein 1 variant b 0.004 0.0562 0.0616
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.3027 0.3027
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.011 0.3027 0.3027
Echinococcus multilocularis casein kinase I delta 0.0144 0.4194 0.4194
Trichomonas vaginalis cyclin A, putative 0.004 0.0562 0.0672
Echinococcus multilocularis cyclin k 0.004 0.0562 0.0562
Brugia malayi Protein kinase domain containing protein 0.0063 0.1366 0.1496
Trichomonas vaginalis cyclin B3, putative 0.004 0.0562 0.0672
Trichomonas vaginalis cyclin B3, putative 0.015 0.4413 0.528
Plasmodium falciparum cyclin 1 0.004 0.0562 0.0797
Loa Loa (eye worm) oxidoreductase 0.01 0.2664 0.2664
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.004 0.0562 0.0797
Loa Loa (eye worm) casein kinase 0.0144 0.422 0.422
Echinococcus multilocularis cyclin dependent kinase 6 0.0209 0.6481 0.6481
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.01 0.2653 0.2653
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Echinococcus granulosus G1:S specific cyclin D1 0.0222 0.6956 0.6956
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Echinococcus multilocularis aldehyde reductase 0.0071 0.1647 0.1647
Echinococcus multilocularis casein kinase I gamma 0.0152 0.4474 0.4474
Echinococcus multilocularis cyclin G2 0.004 0.0562 0.0562
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.1549 0.1853
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.1025 0.1744
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0172 0.0205
Trichomonas vaginalis aldo/keto reductase, putative 0.01 0.2664 0.3187
Onchocerca volvulus 0.01 0.2664 0.3069
Trypanosoma brucei mitotic cyclin 0.004 0.0562 0.0477
Leishmania major casein kinase, putative 0.0144 0.4194 0.4914
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0142 0.0142
Trichomonas vaginalis cyclins, putative 0.0262 0.8359 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0262 0.8359 0.9158
Loa Loa (eye worm) hypothetical protein 0.0103 0.2773 0.2773
Brugia malayi p70 ribosomal S6 kinase beta 0.0057 0.1158 0.1269
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.004 0.0562 0.0797
Echinococcus granulosus neuroglian 0.0038 0.0481 0.0481
Plasmodium falciparum cyclin 0.015 0.4413 0.8661
Trypanosoma brucei cyclin 9 0.004 0.0562 0.0477
Echinococcus multilocularis casein kinase I alpha 0.0144 0.4194 0.4194
Trichomonas vaginalis aldo/keto reductase, putative 0.01 0.2664 0.3187
Brugia malayi Casein kinase II, alpha chain 0.0169 0.5069 0.5554
Echinococcus multilocularis cyclin t1 0.004 0.0562 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.6481 0.6481
Trypanosoma cruzi cyclin, putative 0.0262 0.8359 1
Loa Loa (eye worm) cyclin C 0.0122 0.3428 0.3428
Echinococcus multilocularis aldo keto reductase 0.01 0.2664 0.2664
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0562 0.0562
Toxoplasma gondii AGC kinase 0.0057 0.1158 0.2015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.1249 0.1249
Echinococcus multilocularis cpg binding protein 0.003 0.0199 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.4474 0.4474
Echinococcus multilocularis Glutaredoxin protein 5 0.0033 0.0313 0.0313
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Giardia lamblia Casein kinase II beta chain 0.0044 0.0708 0.0187
Trichomonas vaginalis cyclin D, putative 0.004 0.0562 0.0672
Schistosoma mansoni tyrosine kinase 0.0102 0.2742 0.2742
Entamoeba histolytica casein kinase, putative 0.0169 0.5069 0.6064
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0201
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.3027 0.3488
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Brugia malayi casein kinase I 0.0144 0.4194 0.4595
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0068 0.1549 0.1549
Toxoplasma gondii cyclin 4, putative 0.004 0.0562 0.0797
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0562 0.0477
Entamoeba histolytica aldose reductase, putative 0.01 0.2664 0.3187
Echinococcus granulosus cyclin dependent kinase 0.011 0.3027 0.3027
Loa Loa (eye worm) hypothetical protein 0.0222 0.6956 0.6956
Mycobacterium leprae Conserved hypothetical protein 0.0071 0.1647 0.5922
Trichomonas vaginalis cyclin B3, putative 0.004 0.0562 0.0672
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Loa Loa (eye worm) hypothetical protein 0.0045 0.0738 0.0738
Echinococcus multilocularis G1:S specific cyclin D1 0.0222 0.6956 0.6956
Trichomonas vaginalis cyclin D, putative 0.015 0.4413 0.528
Loa Loa (eye worm) TK/INSR protein kinase 0.0063 0.1366 0.1366
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0309 1 1
Schistosoma mansoni tyrosine kinase 0.0102 0.2742 0.2742
Trichomonas vaginalis cyclin B, putative 0.015 0.4413 0.528
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0562 0.0616
Plasmodium falciparum casein kinase II beta chain 0.0044 0.0708 0.1095
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0562 0.0562
Onchocerca volvulus 0.0029 0.0172 0.0035
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0172 0.0205
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Schistosoma mansoni serine/threonine-protein kinase 0.004 0.0567 0.0567
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.004 0.0562 0.0797
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0044 0.0708 0.0655
Trypanosoma cruzi cyclin, putative 0.0262 0.8359 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0057 0.1158 0.1158
Schistosoma mansoni tyrosine kinase 0.0165 0.4952 0.4952
Onchocerca volvulus Tyrosine kinase homolog 0.0188 0.5768 0.6847
Trypanosoma brucei Casein kinase II 0.0169 0.5069 0.5982
Echinococcus granulosus casein kinase ii subunit beta 0.0044 0.0708 0.0708
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0567 0.0679
Giardia lamblia Aldose reductase 0.01 0.2664 0.2696
Echinococcus multilocularis voltage gated potassium channel subunit 0.0029 0.0172 0.0172
Leishmania major mitotic cyclin, putative 0.004 0.0562 0.0477
Echinococcus granulosus aldehyde reductase 0.0071 0.1647 0.1647
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0203 0.0203
Leishmania major casein kinase II, putative 0.0169 0.5069 0.5982
Echinococcus granulosus aldo keto reductase 0.01 0.2664 0.2664
Entamoeba histolytica cyclin, domain containing protein 0.004 0.0562 0.0672
Trichomonas vaginalis cyclins, putative 0.0262 0.8359 1
Brugia malayi hypothetical protein 0.0148 0.4347 0.4762
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0172 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.011 0.3027 0.3027
Leishmania major mitotic cyclin, putative 0.004 0.0562 0.0477
Trichomonas vaginalis cyclins, putative 0.0262 0.8359 1
Plasmodium vivax unspecified product 0.0169 0.5069 1
Plasmodium falciparum casein kinase II beta chain 0.0044 0.0708 0.1095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Schistosoma mansoni cyclin k 0.004 0.0562 0.0562
Schistosoma mansoni pol-related 0.01 0.2664 0.2664
Toxoplasma gondii hypothetical protein 0.011 0.3007 0.5789
Onchocerca volvulus 0.01 0.2664 0.3069
Brugia malayi cell division control protein 2 homolog 0.011 0.3027 0.3316
Echinococcus granulosus cyclin G2 0.004 0.0562 0.0562
Echinococcus granulosus cyclins 0.015 0.4413 0.4413
Onchocerca volvulus 0.01 0.2664 0.3069
Echinococcus granulosus cyclins 0.004 0.0562 0.0562
Loa Loa (eye worm) protein kinase domain-containing protein 0.0152 0.4474 0.4474
Echinococcus granulosus casein kinase I alpha 0.0144 0.4194 0.4194
Mycobacterium ulcerans oxidoreductase 0.01 0.2664 1
Entamoeba histolytica cyclin family protein 0.015 0.4413 0.528
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.01 0.2664 0.3044
Loa Loa (eye worm) hypothetical protein 0.0182 0.5549 0.5549
Echinococcus granulosus cyclin dependent kinase 1 0.011 0.3027 0.3027
Echinococcus granulosus casein kinase I delta 0.0144 0.4194 0.4194
Schistosoma mansoni cell adhesion molecule 0.003 0.0201 0.0201
Onchocerca volvulus 0.0167 0.5004 0.5917
Echinococcus granulosus nervana 2 0.0033 0.0313 0.0313
Schistosoma mansoni aldo-keto reductase 0.01 0.2664 0.2664
Echinococcus multilocularis cyclin y 0.004 0.0562 0.0562
Entamoeba histolytica cyclin, putative 0.0262 0.8359 1
Trypanosoma brucei cdc2-related kinase 1 0.011 0.3027 0.3488
Echinococcus multilocularis casein kinase ii subunit alpha 0.0169 0.5069 0.5069
Brugia malayi Cyclin, N-terminal domain containing protein 0.0284 0.9128 1
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.3027 0.3488
Echinococcus granulosus epidermal growth factor receptor 0.0186 0.5666 0.5666
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.004 0.0562 0.0797
Schistosoma mansoni cyclin B 0.0262 0.8359 0.8359
Trypanosoma cruzi casein kinase, putative 0.0144 0.4194 0.4914
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0562 0.0672
Onchocerca volvulus 0.0136 0.394 0.4623
Trypanosoma cruzi casein kinase II, putative 0.0169 0.5069 0.5982
Leishmania major cyclin 0.0262 0.8359 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.0562 0.0562
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0136 0.394 0.4603
Trypanosoma brucei cyclin 3 0.004 0.0562 0.0477
Trichomonas vaginalis cyclins, putative 0.015 0.4413 0.528
Onchocerca volvulus Cyclin L homolog 0.004 0.0562 0.051
Echinococcus granulosus casein kinase I alpha 0.0144 0.4194 0.4194
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Echinococcus granulosus fibroblast growth factor receptor 4 0.0165 0.4952 0.4952
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0165 0.4952 0.4952
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Leishmania major cyclin 9, putative 0.004 0.0562 0.0477
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0567 0.0679
Echinococcus multilocularis cyclin B3 1 0.015 0.4413 0.4413
Trypanosoma cruzi rac serine-threonine kinase, putative 0.004 0.0567 0.0484
Loa Loa (eye worm) hypothetical protein 0.0112 0.3101 0.3101
Plasmodium vivax hypothetical protein, conserved 0.004 0.0562 0.0797
Entamoeba histolytica protein kinase 2, putative 0.004 0.0567 0.0679
Brugia malayi MAP kinase sur-1 0.0068 0.1549 0.1697
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0309 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.3027 0.3027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Entamoeba histolytica cell division protein kinase 2, putative 0.011 0.3027 0.3621
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0029 0.0172 0.0172
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0044 0.0708 0.0688
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Trichomonas vaginalis cyclin B, putative 0.0262 0.8359 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0562 0.0616
Echinococcus multilocularis cyclin dependent kinase 5 0.011 0.3027 0.3027
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Trichomonas vaginalis CMGC family protein kinase 0.011 0.3027 0.3621
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0562 0.0616
Trichomonas vaginalis cyclin B, putative 0.004 0.0562 0.0672
Toxoplasma gondii ck2 beta subunit 0.0044 0.0708 0.1095
Brugia malayi Cyclin, N-terminal domain containing protein 0.0262 0.8359 0.9158
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.01 0.2664 0.3187
Brugia malayi casein kinase 1, delta 0.0144 0.4194 0.4595
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0044 0.0708 0.0655
Schistosoma mansoni casein kinase II beta subunit 0.0044 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Echinococcus granulosus cyclins 0.015 0.4413 0.4413
Onchocerca volvulus Protein CNPPD1 homolog 0.004 0.0562 0.051
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.01 0.2664 0.2918
Trypanosoma brucei rac serine-threonine kinase, putative 0.0057 0.1158 0.1205
Loa Loa (eye worm) hypothetical protein 0.0148 0.4347 0.4347
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Loa Loa (eye worm) hypothetical protein 0.0262 0.8359 0.8359
Onchocerca volvulus Cyclin L homolog 0.004 0.0562 0.051
Trypanosoma cruzi rac serine-threonine kinase, putative 0.004 0.0567 0.0484
Echinococcus granulosus cyclin dependent kinase 7 0.01 0.2653 0.2653
Giardia lamblia Kinase, CMGC MAPK 0.0068 0.1549 0.1266
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Loa Loa (eye worm) hypothetical protein 0.0309 1 1
Brugia malayi Protein kinase domain containing protein 0.011 0.3027 0.3316
Echinococcus granulosus cyclins 0.015 0.4413 0.4413
Trypanosoma cruzi Protein kinase B 0.004 0.0567 0.0484
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0068 0.1549 0.1682
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.1549 0.1682
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.3027 0.3027
Schistosoma mansoni serine/threonine protein kinase 0.01 0.2653 0.2653
Trypanosoma cruzi casein kinase, putative 0.0144 0.4194 0.4914
Entamoeba histolytica aldose reductase, putative 0.01 0.2664 0.3187
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.01 0.2664 0.2918
Echinococcus granulosus epidermal growth factor receptor 0.0102 0.2742 0.2742
Brugia malayi Furin-like cysteine rich region family protein 0.0186 0.5666 0.6208
Echinococcus multilocularis casein kinase I alpha 0.0144 0.4194 0.4194
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0122 0.3428 0.3428
Onchocerca volvulus 0.01 0.2664 0.3069
Echinococcus multilocularis aldo keto reductase 0.01 0.2664 0.2664
Echinococcus granulosus cyclin y 0.004 0.0562 0.0562
Schistosoma mansoni cyclin B3 0.0284 0.9128 0.9128
Echinococcus multilocularis epidermal growth factor receptor 0.0102 0.2742 0.2742
Echinococcus multilocularis cyclin A3 4 0.004 0.0562 0.0562
Echinococcus granulosus cyclin B3 1 0.015 0.4413 0.4413
Trypanosoma brucei prostaglandin f synthase 0.01 0.2664 0.3044
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.004 0.0562 0.0477
Trypanosoma cruzi mitotic cyclin, putative 0.004 0.0562 0.0477
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0044 0.0708 0.0688
Trichomonas vaginalis cyclins, putative 0.0262 0.8359 1
Entamoeba histolytica cyclin family protein 0.015 0.4413 0.528
Brugia malayi hypothetical protein 0.004 0.0562 0.0616
Trypanosoma cruzi casein kinase, putative 0.0144 0.4194 0.4914
Giardia lamblia Aldose reductase 0.01 0.2664 0.2696
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Echinococcus multilocularis cyclin b3 0.015 0.4413 0.4413
Loa Loa (eye worm) cyclin domain-containing protein 0.0198 0.6113 0.6113
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0102 0.2742 0.2742
Trichomonas vaginalis cyclins, putative 0.004 0.0562 0.0672
Trichomonas vaginalis AGC family protein kinase 0.0057 0.1158 0.1386
Echinococcus multilocularis cyclin B 0.0262 0.8359 0.8359
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.01 0.2653 0.2653
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.3027 0.3027
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0029 0.0172 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0165 0.4952 0.4952
Echinococcus granulosus insulin receptor 0.0063 0.1366 0.1366
Echinococcus multilocularis casein kinase i 0.0144 0.4194 0.4194
Schistosoma mansoni cyclin G 0.004 0.0562 0.0562
Echinococcus multilocularis cyclin G2 0.004 0.0562 0.0562
Loa Loa (eye worm) oxidoreductase 0.01 0.2664 0.2664
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Echinococcus granulosus casein kinase I gamma 0.0152 0.4474 0.4474
Echinococcus multilocularis mitogen activated protein kinase 0.0068 0.1549 0.1549
Trichomonas vaginalis aldo-keto reductase, putative 0.01 0.2664 0.3187
Trichomonas vaginalis cyclins, putative 0.0153 0.4507 0.5392
Giardia lamblia Cyclin A 0.015 0.4413 0.494
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.01 0.2664 0.2664
Brugia malayi Immunoglobulin I-set domain containing protein 0.0203 0.6276 0.6876
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0044 0.0708 0.0655
Plasmodium falciparum casein kinase 2, alpha subunit 0.0169 0.5069 1
Schistosoma mansoni cpg binding protein 0.003 0.0199 0.0199
Echinococcus granulosus Cyclin L1 0.004 0.0562 0.0562
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.01 0.2664 0.3187
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0708 0.0846
Echinococcus granulosus mitogen activated protein kinase 3 0.0068 0.1549 0.1549
Echinococcus granulosus casein kinase I alpha 0.0144 0.4194 0.4194
Schistosoma mansoni cyclin G2 0.004 0.0562 0.0562
Trypanosoma brucei protein kinase, putative 0.0068 0.1549 0.1682
Echinococcus granulosus aldo keto reductase family 1 member B4 0.01 0.2664 0.2664
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.1549 0.1682
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.5069 0.6064
Plasmodium vivax cyclin homologue, putative 0.004 0.0562 0.0797
Plasmodium vivax casein kinase II beta chain, putative 0.0044 0.0708 0.1095
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.5069 0.6064
Onchocerca volvulus 0.0144 0.4194 0.4932
Brugia malayi Protein kinase domain containing protein 0.0152 0.4474 0.4902
Plasmodium vivax protein kinase Crk2 0.011 0.3027 0.583
Echinococcus multilocularis cyclins 0.015 0.4413 0.4413
Echinococcus granulosus aldo keto reductase 0.01 0.2664 0.2664
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.004 0.0562 0.0562
Echinococcus multilocularis neuroglian 0.0038 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.004 0.0562 0.0562
Leishmania major prostaglandin f synthase, putative 0.01 0.2664 0.3044

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0 uM Inhibition of Insulin receptor ChEMBL. 15999992
IC50 (binding) = 0.003 uM Inhibition of CDK5/p35 ChEMBL. 15999992
IC50 (binding) = 0.003 uM Inhibition of CDK5/p35 ChEMBL. 15999992
IC50 (binding) = 0.007 uM Inhibitory concentration of compound against CDK2/cyclin A ChEMBL. 15999992
IC50 (binding) = 0.007 uM Inhibitory concentration of compound against CDK2/cyclin A ChEMBL. 15999992
IC50 (binding) = 0.02 uM Inhibition of Glycogen synthase kinase-3 beta ChEMBL. 15999992
IC50 (binding) = 0.021 uM Inhibition of cyclin dependent kinase CDK1 ChEMBL. 15999992
IC50 (binding) = 0.021 uM Inhibition of CDK1/cyclin B ChEMBL. 15999992
IC50 (binding) = 0.021 uM Inhibition of cyclin dependent kinase CDK1 ChEMBL. 15999992
IC50 (binding) = 0.021 uM Inhibition of CDK1/cyclin B ChEMBL. 15999992
IC50 (functional) = 0.023 uM Inhibitory concentration of compound against growth of HCT-116 cells ChEMBL. 15999992
IC50 (functional) = 0.023 uM Inhibitory concentration of compound against growth of HCT-116 cells ChEMBL. 15999992
IC50 (functional) = 0.028 uM Inhibitory concentration of compound against growth of A-375 cells ChEMBL. 15999992
IC50 (functional) = 0.028 uM Inhibitory concentration of compound against growth of A-375 cells ChEMBL. 15999992
IC50 (functional) = 0.031 uM Inhibitory concentration of compound against growth of U-937 cells ChEMBL. 15999992
IC50 (functional) = 0.031 uM Inhibitory concentration of compound against growth of U-937 cells ChEMBL. 15999992
IC50 (functional) = 0.033 uM Inhibitory concentration of compound against growth of HeLa cells ChEMBL. 15999992
IC50 (functional) = 0.033 uM Inhibitory concentration of compound against growth of HeLa cells ChEMBL. 15999992
IC50 (binding) = 0.126 uM Inhibition of CDK7/cyclin H ChEMBL. 15999992
IC50 (binding) = 0.126 uM Inhibition of CDK7/cyclin H ChEMBL. 15999992
IC50 (functional) = 0.228 uM Inhibitory concentration of compound against growth of MES SA cells (low p glycoprotein) ChEMBL. 15999992
IC50 (functional) = 0.235 uM Inhibitory concentration of compound against growth of MES SA/Dx 5 cells (high p glycoprotein) ChEMBL. 15999992
IC50 (binding) = 0.308 uM Inhibition of CDK4/cyclin D1 ChEMBL. 15999992
IC50 (binding) = 0.308 uM Inhibition of CDK4/cyclin D1 ChEMBL. 15999992
IC50 (binding) = 0.356 uM Inhibition of CDK6/cyclin D3 ChEMBL. 15999992
IC50 (binding) = 0.356 uM Inhibition of CDK6/cyclin D3 ChEMBL. 15999992
IC50 (binding) = 3.05 uM Inhibition of Casein kinase I ChEMBL. 15999992
IC50 (binding) = 3.05 uM Inhibition of Casein kinase I ChEMBL. 15999992
IC50 (binding) = 3.5 uM Inhibition of vascular endothelial growth factor receptor 2 ChEMBL. 15999992
IC50 (binding) = 3.5 uM Inhibition of vascular endothelial growth factor receptor 2 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Casein kinase II ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Epidermal growth factor receptor 1 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Fibroblast growth factor receptor 2 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of ERK 2 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Platelet derived growth factor receptor ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Cyclin-dependent kinase 1-cyclin B ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of PKB beta ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Protein kinase C gamma ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of [Ca2+]/Calmodulin dependent kinase ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Casein kinase II ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Epidermal growth factor receptor 1 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Fibroblast growth factor receptor 2 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of ERK 2 ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Platelet derived growth factor receptor ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of Cyclin-dependent kinase 1-cyclin B ChEMBL. 15999992
IC50 (binding) > 10 uM Inhibition of PKB beta ChEMBL. 15999992

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15999992

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.