Detailed information for compound 333500

Basic information

Technical information
  • TDR Targets ID: 333500
  • Name: 1,2,8-trihydroxy-3-methylanthracene-9,10-dion e
  • MW: 270.237 | Formula: C15H10O5
  • H donors: 3 H acceptors: 5 LogP: 2.72 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cccc2c1C(=O)c1c(C2=O)cc(c(c1O)O)C
  • InChi: 1S/C15H10O5/c1-6-5-8-11(15(20)12(6)17)14(19)10-7(13(8)18)3-2-4-9(10)16/h2-5,16-17,20H,1H3
  • InChiKey: CQNVSNFEXPKHGW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1,2,8-trihydroxy-3-methyl-anthracene-9,10-dione
  • 1,2,8-trihydroxy-3-methyl-9,10-anthraquinone
  • 2-hydroxychrysophanol
  • 58322-78-4
  • C10379
  • Norobtusifolin
  • CHEBI:7635
  • 9,10-Anthracenedione, 1,2,8-trihydroxy-3-methyl-
  • LMPK02000040

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi RNase H family protein 0.0067 0.037 0.1398
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0002 0.0006
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0222 0.0865
Schistosoma mansoni hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0037 0.0166 0.0166
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0067 0.0371 0.1779
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0222 0.1064
Onchocerca volvulus 0.0032 0.0134 0.1279
Schistosoma mansoni hypothetical protein 0.007 0.0396 0.0396
Loa Loa (eye worm) TWK-28 protein 0.0067 0.0371 0.0371
Plasmodium falciparum glutathione reductase 0.0026 0.0092 0.0873
Trypanosoma brucei glucosidase, putative 0.0027 0.0098 0.038
Onchocerca volvulus 0.0067 0.0371 0.3702
Brugia malayi G-protein alpha subunit 0.0017 0.0034 0.0129
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0034 0.0129
Schistosoma mansoni GTP-binding protein alpha subunit 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0098 0.0761
Onchocerca volvulus Huntingtin homolog 0.015 0.0938 0.9483
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0017 0.0034 0.0034
Echinococcus granulosus potassium channel subfamily K 8 0.0067 0.0371 0.0371
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0059 0.0316 0.3122
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.004 0.0189 0.0713
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Brugia malayi hypothetical protein 0.0067 0.0371 0.1404
Onchocerca volvulus 0.0032 0.0134 0.1279
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0153 0.0394
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Leishmania major mitochondrial DNA polymerase beta 0.032 0.2087 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0493 0.0493
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0008 0.0008
Echinococcus multilocularis muscleblind protein 1 0.0155 0.097 0.097
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0102 0.0613 0.0613
Brugia malayi beta-lactamase family protein 0.0085 0.0493 0.1865
Trypanosoma brucei calcium-activated potassium channel, putative 0.0067 0.0371 0.1446
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.003 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi Sodium:solute symporter family protein 0.0028 0.011 0.0417
Onchocerca volvulus 0.0054 0.0287 0.2839
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Echinococcus multilocularis chromobox protein 1 0.0052 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0112 0.0679 0.0679
Schistosoma mansoni thymidylate kinase 0.007 0.0396 0.0396
Schistosoma mansoni inositol transporter 0.0028 0.011 0.011
Trypanosoma brucei RNA helicase, putative 0.039 0.2568 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Brugia malayi Serotonin receptor 0.0032 0.0134 0.0506
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0134 0.0134
Wolbachia endosymbiont of Brugia malayi dUTPase 0.0074 0.0421 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0134 0.0134
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0128 0.05
Echinococcus granulosus sodium:glucose cotransporter 2 0.0028 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0008 0.0008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0008 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0095 0.0095
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0052 0.027 0.027
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0268 0.2088
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0134 0.0134
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0008 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0134 0.0134
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0371 0.289
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) heterochromatin protein 1 0.0052 0.0268 0.0268
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0015 0.0072
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0067 0.0371 0.1404
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0134 0.0134
Entamoeba histolytica hypothetical protein 0.0074 0.0421 1
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0067 0.0371 0.0371
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0059 0.0316 0.085
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) MH2 domain-containing protein 0.0079 0.0455 0.0455
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0074 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0034 0.0265
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0198 0.1467
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0085 0.0493 0.0493
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0098 0.0761
Brugia malayi ORL1-like opioid receptor 0.0032 0.0134 0.0506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0031 0.0117
Schistosoma mansoni neuropeptide receptor 0.0032 0.0134 0.0134
Leishmania major phosphatidylinositol kinase related protein, putative 0.0012 0 0.0001
Schistosoma mansoni GTP-binding protein alpha subunit 0.0017 0.0034 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0134 0.0134
Onchocerca volvulus 0.0085 0.0493 0.4946
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0008 0.0008
Echinococcus granulosus sodium:myo inositol cotransporter 0.0028 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0504 0.3337 0.3337
Loa Loa (eye worm) uncoordinated protein 58 0.0067 0.0371 0.0371
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0095 0.0095
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Schistosoma mansoni hypothetical protein 0.0032 0.0134 0.0134
Plasmodium falciparum potassium channel 0.0067 0.0371 0.3715
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0065 0.0361 0.3578
Mycobacterium ulcerans ion transport protein 0.0067 0.0371 0.2827
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0017 0.0034 0.0034
Entamoeba histolytica G protein alpha subunit, putative 0.0017 0.0034 0.0807
Echinococcus multilocularis ribonuclease H1 0.0067 0.037 0.037
Mycobacterium ulcerans thymidylate synthase 0.0158 0.0989 0.7677
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0022 0.0068 0.0068
Leishmania major hypothetical protein, conserved 0.0022 0.0067 0.0323
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0028 0.011 0.011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0212 0.0212
Mycobacterium tuberculosis Probable lipase LipD 0.0085 0.0493 0.1343
Brugia malayi RNase H family protein 0.0067 0.037 0.1398
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0129 0.1002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.106 0.2923
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0085 0.0493 0.3785
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0134 0.0506
Brugia malayi Pre-SET motif family protein 0.0019 0.0045 0.0169
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0198 0.0198
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0134 0.0134
Schistosoma mansoni intermediate filament proteins 0.0054 0.0287 0.0287
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0017 0.0034 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0402 0.2644 0.2644
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0134 0.1279
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0134 0.0134
Trichomonas vaginalis ran, putative 0.0013 0.0006 0.0049
Trypanosoma cruzi ribonuclease H1, putative 0.0067 0.037 0.1771
Echinococcus granulosus neutral alpha glucosidase AB 0.0027 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0008 0.0032
Echinococcus granulosus tar DNA binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0212 0.0212
Echinococcus granulosus thymidylate synthase 0.0158 0.0989 0.0989
Brugia malayi prolyl oligopeptidase family protein 0.0023 0.007 0.0266
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0014 0.0015 0.0378
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0134 0.0134
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0034 0.0034
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0153 0.3387
Onchocerca volvulus 0.0032 0.0134 0.1279
Loa Loa (eye worm) transcription factor SMAD2 0.0079 0.0455 0.0455
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0067 0.0371 0.1404
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0427 0.3322
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0098 0.0468
Brugia malayi thymidylate synthase 0.0158 0.0989 0.3739
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0134 0.0134
Schistosoma mansoni ferritin light chain 0.0035 0.0153 0.0153
Onchocerca volvulus 0.0017 0.0034 0.0261
Trypanosoma cruzi ISWI complex protein 0.0022 0.0067 0.0323
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus granulosus neuropeptide receptor 0.0032 0.0134 0.0134
Onchocerca volvulus 0.0032 0.0134 0.1279
Onchocerca volvulus 0.0067 0.0371 0.3702
Echinococcus granulosus GTP binding nuclear protein Ran 0.0013 0.0006 0.0006
Trypanosoma cruzi thymidylate kinase, putative 0.007 0.0396 0.1895
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0172 0.1084 0.1084
Schistosoma mansoni apoferritin-2 0.0035 0.0153 0.0153
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0371 0.289
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0114
Schistosoma mansoni bromodomain containing protein 0.0093 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0688 0.459 0.459
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Brugia malayi AKH receptor 0.0032 0.0134 0.0506
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0134 0.0506
Toxoplasma gondii thioredoxin reductase 0.0026 0.0092 0.0931
Leishmania major ion transport protein-like protein 0.0067 0.0371 0.1779
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Onchocerca volvulus 0.0032 0.0134 0.1279
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0011 0.0054
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0134 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0028 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0153 0.1109
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0067 0.0374 0.0374
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0017 0.0034 0.0265
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0017 0.0034 0.0034
Loa Loa (eye worm) MBCTL1 0.004 0.0189 0.0189
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0326 0.3297
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0008 0.0008
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0014 0.0015 0.0072
Echinococcus granulosus histone acetyltransferase MYST2 0.004 0.0189 0.0189
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0129 0.1002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0008 0.0008
Echinococcus multilocularis lamin dm0 0.0054 0.0287 0.0287
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.004 0.0189 0.0189
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0134 0.0134
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0134 0.0134
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 0.0989
Schistosoma mansoni hypothetical protein 0.0504 0.3337 0.3337
Echinococcus multilocularis chromobox protein 1 0.0052 0.0268 0.0268
Trichomonas vaginalis glutaminase, putative 0.0201 0.1284 1
Schistosoma mansoni calcium-activated potassium channel 0.0067 0.0371 0.0371
Trypanosoma brucei ribonuclease H1 0.0067 0.037 0.144
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0371 0.289
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0008 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.0015 0.0015
Echinococcus multilocularis snurportin 1 0.0332 0.2174 0.2174
Trichomonas vaginalis thymidylate kinase, putative 0.007 0.0396 0.3079
Loa Loa (eye worm) hypothetical protein 0.1485 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 0.4737
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0027 0.0098 0.0988
Entamoeba histolytica hypothetical protein 0.0049 0.0246 0.5843
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0034 0.0034
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Loa Loa (eye worm) hypothetical protein 0.004 0.0189 0.0189
Leishmania major hypothetical protein, conserved 0.0028 0.0105 0.0502
Mycobacterium ulcerans transmembrane cation transporter 0.0067 0.0371 0.2827
Toxoplasma gondii LsmAD domain-containing protein 0.0068 0.0375 0.3797
Brugia malayi Importin beta-1 subunit 0.0031 0.0128 0.0485
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0054 0.0287 0.0287
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0134 0.0134
Loa Loa (eye worm) TAR-binding protein 0.0044 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0098 0.2319
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0008 0.0008
Echinococcus multilocularis high affinity choline transporter 1 0.0258 0.167 0.167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Onchocerca volvulus 0.0145 0.09 0.9095
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0153 0.1109
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0031 0.0031
Onchocerca volvulus 0.0023 0.0071 0.0641
Schistosoma mansoni ferritin 0.0035 0.0153 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0008 0.0032
Mycobacterium tuberculosis Probable lipase LipE 0.0085 0.0493 0.1343
Loa Loa (eye worm) TWK-7 protein 0.0067 0.0371 0.0371
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0134 0.0134
Trichomonas vaginalis esterase, putative 0.0085 0.0493 0.384
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0067 0.0371 0.1404
Onchocerca volvulus 0.0032 0.0134 0.1279
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0371 0.1779
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Schistosoma mansoni ferritin 0.0035 0.0153 0.0153
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0067 0.0371 0.1404
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0493 0.4957
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0085 0.0085
Schistosoma mansoni glutaminase 0.0201 0.1284 0.1284
Trypanosoma cruzi PAB1-binding protein , putative 0.0068 0.0375 0.1798
Trypanosoma brucei ingi protein (ORF1) 0.0076 0.043 0.1673
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0134 0.0134
Echinococcus granulosus intermediate filament protein 0.0054 0.0287 0.0287
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0008 0.0008
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0017 0.0034 0.0034
Loa Loa (eye worm) prolyl oligopeptidase 0.0067 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis expressed protein 0.0035 0.0153 0.0153
Leishmania major alpha glucosidase II subunit, putative 0.0027 0.0098 0.0468
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0041 0.0198 0.0198
Onchocerca volvulus 0.0067 0.0371 0.3702
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0128 0.0128
Loa Loa (eye worm) mbt repeat family protein 0.0035 0.0155 0.0155
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0212 0.0212
Echinococcus granulosus thymidylate kinase 0.007 0.0396 0.0396
Brugia malayi Bromodomain containing protein 0.011 0.0666 0.252
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0074 0.0421 1
Brugia malayi GnHR receptor homolog 0.0032 0.0134 0.0506
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0289 0.1384
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0017 0.0036 0.0036
Mycobacterium ulcerans lipase LipD 0.0085 0.0493 0.3785
Echinococcus multilocularis thymidylate synthase 0.0158 0.0989 0.0989
Echinococcus multilocularis histone acetyltransferase MYST2 0.004 0.0189 0.0189
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.0015 0.0355
Echinococcus multilocularis solute carrier family 5 0.0028 0.011 0.011
Echinococcus multilocularis calcium activated potassium channel variant 0.0067 0.0371 0.0371
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0037 0.0166 0.0166
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0074 0.0421 0.0421
Schistosoma mansoni ap endonuclease 0.0014 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0067 0.037 0.8729
Onchocerca volvulus Putative thymidylate kinase 0.007 0.0396 0.3949
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0067 0.0371 0.1779
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.012 0.0732 0.0732
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0074 0.0421 1
Brugia malayi G-protein coupled receptor 0.0032 0.0134 0.0506
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0134 0.0134
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0134 0.0134
Leishmania major potassium channel subunit-like protein 0.0067 0.0371 0.1779
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0008 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0088 0.0688
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.004 0.0189 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0493 0.2363
Echinococcus granulosus zinc finger protein 0.003 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0134 0.0134
Schistosoma mansoni amine GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.043 0.1673
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0015
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0067 0.0371 0.0371
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0074 0.0421 0.3281
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0056 0.0438
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0017 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0067 0.0371 0.1779
Brugia malayi CHD4 protein 0.0013 0.0005 0.0017
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0134 0.0134
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0031 0.0149
Entamoeba histolytica Ran family GTPase 0.0013 0.0006 0.0149
Echinococcus multilocularis serotonin receptor 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0217 0.1387 0.1387
Loa Loa (eye worm) hypothetical protein 0.015 0.0938 0.0938
Mycobacterium leprae conserved hypothetical protein 0.0085 0.0493 0.493
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0128 0.05
Mycobacterium tuberculosis Probable hydrolase 0.0085 0.0493 0.1343
Onchocerca volvulus Huntingtin homolog 0.015 0.0938 0.9483
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0074 0.0421 1
Echinococcus granulosus geminin 0.0504 0.3337 0.3337
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0098 0.0761
Giardia lamblia Hypothetical protein 0.0067 0.0371 0.9387
Loa Loa (eye worm) hypothetical protein 0.015 0.0938 0.0938
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0098 0.2319
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0028 0.011 0.011
Echinococcus multilocularis musashi 0.0054 0.0287 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0056 0.0438
Onchocerca volvulus 0.0062 0.0337 0.3351
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0023 0.007 0.0337
Brugia malayi ecdysteroid receptor 0.0013 0.0008 0.0032
Brugia malayi sulfakinin receptor protein 0.0032 0.0134 0.0506
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0074 0.0421 0.4225
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0158 0.0989 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0098 0.0761
Mycobacterium ulcerans hypothetical protein 0.0168 0.106 0.8238
Mycobacterium ulcerans beta-lactamase 0.0085 0.0493 0.3785
Schistosoma mansoni coup transcription factor 0.0013 0.0008 0.0008
Onchocerca volvulus 0.0017 0.0034 0.0261
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.0015 0.001
Onchocerca volvulus 0.003 0.0118 0.1119
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0023 0.007 0.0274
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Echinococcus multilocularis geminin 0.0504 0.3337 0.3337
Leishmania major calcium/potassium channel (CAKC), putative 0.0067 0.0371 0.1779
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni lamin 0.0054 0.0287 0.0287
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0098 0.0761
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Brugia malayi TAR-binding protein 0.0044 0.0214 0.081
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0944 0.4523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0031 0.0242
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus multilocularis twik family of potassium channels 0.0067 0.0371 0.0371
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0017 0.0034 0.0129
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni alpha-glucosidase 0.0103 0.0618 0.0618
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 0.4737
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Schistosoma mansoni biogenic amine receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) thymidylate synthase 0.0158 0.0989 0.0989
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0017 0.0034 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0402 0.2644 0.2644
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Plasmodium falciparum thioredoxin reductase 0.0026 0.0092 0.0873
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Schistosoma mansoni chromobox protein 0.0052 0.0268 0.0268
Trypanosoma brucei mitochondrial DNA polymerase beta 0.032 0.2087 0.8127
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0134 0.0134
Echinococcus granulosus SAM and MBT domain containing protein 0.0035 0.0155 0.0155
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0134 0.0134
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 0.385
Brugia malayi beta-lactamase 0.0085 0.0493 0.1865
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0067 0.0374 0.0374
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0134 0.0134
Echinococcus multilocularis small conductance calcium activated potassium 0.1485 1 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0044 0.0214 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0008 0.0032
Schistosoma mansoni myosin xvIII 0.0032 0.0134 0.0134
Schistosoma mansoni calcium-activated potassium channel 0.1306 0.8783 0.8783
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0008 0.0008
Onchocerca volvulus 0.0028 0.011 0.1038
Mycobacterium ulcerans hypothetical protein 0.0085 0.0493 0.3785
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0134 0.0134
Schistosoma mansoni thymidylate kinase 0.007 0.0396 0.0396
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0008 0.0008
Toxoplasma gondii exonuclease III APE 0.0014 0.0015 0.0151
Echinococcus granulosus expressed protein 0.0017 0.0034 0.0034
Schistosoma mansoni chromobox protein 0.0052 0.0268 0.0268
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0141 0.0877 0.0877
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0008 0.0008
Loa Loa (eye worm) glutaminase 0.0201 0.1284 0.1284
Onchocerca volvulus 0.0032 0.0134 0.1279
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0017 0.0034 0.0129
Schistosoma mansoni biogenic amine receptor 0.0032 0.0134 0.0134
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0037 0.0166 0.0629
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0134 0.0134
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0013 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0102 0.0102
Onchocerca volvulus 0.0158 0.0989 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0402 0.2644 0.2644
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0027 0.0098 0.0098
Echinococcus granulosus lamin dm0 0.0054 0.0287 0.0287
Wolbachia endosymbiont of Brugia malayi deoxycytidine triphosphate deaminase 0.0026 0.0092 0.1896
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Schistosoma mansoni microtubule-associated protein tau 0.0411 0.271 0.271
Onchocerca volvulus 0.0032 0.0134 0.1279
Echinococcus multilocularis thymidylate kinase 0.007 0.0396 0.0396
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0023 0.007 0.0712
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0017 0.0034 0.0265
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0023 0.007 0.0337
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0017 0.0034 0.0034
Mycobacterium leprae Probable lipase LipE 0.0085 0.0493 0.493
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0008 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0098 0.0761
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus granulosus g protein coupled receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0134 0.0134
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0114 0.1075
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0017 0.0034 0.0129
Schistosoma mansoni sex comb on midleg homolog 0.0035 0.0155 0.0155
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0041 0.0198 0.052
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0067 0.0371 0.1404
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0008 0.0032
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0011 0.0054
Plasmodium falciparum importin beta, putative 0.0031 0.0128 0.1242
Toxoplasma gondii hypothetical protein 0.0052 0.0267 0.27
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0034 0.0265
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0017 0.0034 0.0034
Brugia malayi RE15519p 0.0032 0.0134 0.0506
Echinococcus granulosus tumor protein p63 0.0423 0.2787 0.2787
Leishmania major hypothetical protein, conserved 0.0067 0.0371 0.1779
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0067 0.0371 0.1404
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0008 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0022 0.0068 0.0068
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0134 0.0134
Schistosoma mansoni ferritin 0.0035 0.0153 0.0153
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.1485 1 1
Echinococcus granulosus orexin receptor type 2 0.0032 0.0134 0.0134
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0088 0.0688
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Schistosoma mansoni adenoreceptor 0.0032 0.0134 0.0134
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0022 0.0068 0.0068
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0158 0.0989 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0294 0.0294
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0141 0.0877 0.0877
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0127 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0089
Echinococcus granulosus serotonin receptor 0.0032 0.0134 0.0134
Echinococcus granulosus chromobox protein 1 0.0052 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0023 0.0071 0.0071
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0134 0.0134
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0059 0.0316 0.085
Onchocerca volvulus 0.0032 0.0134 0.1279
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Schistosoma mansoni ran 0.0013 0.0006 0.0006
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0062 0.0337 0.0337
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0134 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni opsin-like receptor 0.0032 0.0134 0.0134
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0015 0.0088
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0134 0.0506
Entamoeba histolytica hypothetical protein 0.0022 0.0068 0.1625
Brugia malayi Melatonin receptor type 1A 0.0032 0.0134 0.0506
Plasmodium vivax glutathione reductase, putative 0.0026 0.0092 0.0873
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0134 0.0506
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Leishmania major trypanothione reductase 0.0026 0.0092 0.0441
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0067 0.0374 0.0374
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0017 0.0034 0.0034
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0067 0.0371 0.1404
Brugia malayi G protein-coupled receptor 0.0032 0.0134 0.0506
Loa Loa (eye worm) G protein alpha subunit 3 0.0017 0.0034 0.0034
Onchocerca volvulus 0.0032 0.0134 0.1279
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0008 0.0032
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.015 0.015
Schistosoma mansoni hypothetical protein 0.039 0.2568 0.2568
Echinococcus granulosus somatostatin receptor 0.0032 0.0134 0.0134
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.003 0.0123 0.0123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0198 0.0198
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0015 0.0088
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0134 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0493 0.384
Echinococcus granulosus polycomb protein SCMH1 0.0035 0.0155 0.0155
Brugia malayi thymidylate kinase 0.007 0.0396 0.1496
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0008 0.0008
Plasmodium vivax potassium channel, putative 0.0067 0.0371 0.3715
Trypanosoma cruzi ribonuclease H1, putative 0.0067 0.037 0.1771
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni apoferritin-2 0.0035 0.0153 0.0153
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0015 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.0085 0.0493 0.192
Brugia malayi hypothetical protein 0.0017 0.0034 0.0129
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.0015 0.0015
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0017 0.0034 0.0034
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0067 0.0371 0.1446
Plasmodium vivax importin-beta 2, putative 0.0031 0.0128 0.1242
Brugia malayi mbt repeat family protein 0.0035 0.0155 0.0588
Onchocerca volvulus 0.0054 0.0287 0.2839
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0134 0.0134
Brugia malayi Bromodomain containing protein 0.0055 0.0294 0.1111
Entamoeba histolytica acyl-coA synthetase, putative 0.0014 0.0011 0.027
Schistosoma mansoni calcium-activated potassium channel 0.1485 1 1
Echinococcus granulosus fmrfamide receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis potassium channel subfamily K 8 0.0067 0.0371 0.0371
Echinococcus granulosus high affinity choline transporter 1 0.0258 0.167 0.167
Onchocerca volvulus 0.0069 0.0388 0.3875
Echinococcus granulosus ferritin 0.0035 0.0153 0.0153
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0074 0.0421 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0134 0.0134
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0034 0.0265
Echinococcus granulosus microtubule associated protein 2 0.0411 0.271 0.271
Mycobacterium ulcerans deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0026 0.0092 0.0633
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0074 0.0421 0.4262
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.0944 0.3676
Brugia malayi Muscleblind-like protein 0.0155 0.097 0.3668
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0258 0.167 0.167
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 1
Onchocerca volvulus 0.0032 0.0134 0.1279
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0067 0.0371 0.1404
Schistosoma mansoni importin beta-1 0.0031 0.0128 0.0128
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.007 0.0396 0.1071
Echinococcus granulosus Dipeptidyl peptidase 9 0.0023 0.007 0.007
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0067 0.0371 0.0371
Entamoeba histolytica deoxycytidine triphosphate deaminase, putative 0.0026 0.0092 0.2184
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0067 0.0371 0.1779
Leishmania major hypothetical protein, conserved 0.0085 0.0493 0.2363
Entamoeba histolytica hypothetical protein 0.0022 0.0068 0.1625
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0017 0.0034 0.0034
Echinococcus granulosus chromobox protein 1 0.0052 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0067 0.0371 0.1404
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni lamin 0.0054 0.0287 0.0287
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0076 0.043 0.1673
Trypanosoma brucei thymidylate kinase, putative 0.007 0.0396 0.154
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0019 0.0045 0.0451
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0198 0.1467
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0134 0.0134
Echinococcus multilocularis polycomb protein SCMH1 0.0035 0.0155 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0008 0.0032
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0013 0.0006 0.0159
Echinococcus granulosus calcium activated potassium channel variant 0.0067 0.0371 0.0371
Schistosoma mansoni biogenic amine receptor 0.0032 0.0134 0.0134
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0067 0.0371 0.8811
Brugia malayi mbt repeat family protein 0.0035 0.0155 0.0588
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0098 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0371 0.1779
Echinococcus granulosus twik family of potassium channels 0.0067 0.0371 0.0371
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0008 0.0008
Echinococcus granulosus lamin 0.0054 0.0287 0.0287
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0008 0.0008
Mycobacterium ulcerans glutaminase 0.0201 0.1284 1
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0091 0.0091
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0134 0.0134
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0013 0.0006 0.0024
Echinococcus granulosus hypothetical protein 0.0032 0.0134 0.0134
Plasmodium vivax potassium channel, putative 0.0067 0.0371 0.3715
Brugia malayi follicle stimulating hormone receptor 0.0172 0.1084 0.4101
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0287 0.1084
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.2087 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0493 0.384
Echinococcus granulosus beta LACTamase domain containing family member 0.0085 0.0493 0.0493
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0025 0.0085 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0098 0.0761
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0008 0.0032
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.003 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Plasmodium vivax SET domain protein, putative 0.0019 0.0045 0.039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0134 0.0134
Brugia malayi MH2 domain containing protein 0.0079 0.0455 0.172
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0059 0.0318 0.0318
Mycobacterium tuberculosis Probable reductase 0.0059 0.0316 0.085
Echinococcus multilocularis potassium channel subfamily K 0.0067 0.0371 0.0371
Mycobacterium tuberculosis Probable dehydrogenase 0.0059 0.0316 0.085
Echinococcus granulosus allatostatin A receptor 0.0032 0.0134 0.0134
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0008 0.0008
Schistosoma mansoni alpha-glucosidase 0.0103 0.0618 0.0618
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0134 0.0134
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0023 0.007 0.0274
Trypanosoma cruzi ion transport protein, putative 0.0067 0.0371 0.1779
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0017 0.0034 0.0129
Mycobacterium ulcerans thymidylate kinase 0.007 0.0396 0.3017
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0017 0.0034 0.0129
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0017 0.0034 0.0129
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0008 0.0008
Brugia malayi Calcitonin receptor-like protein seb-1 0.0037 0.0166 0.0629
Echinococcus multilocularis somatostatin receptor 0.0032 0.0134 0.0134
Brugia malayi hypothetical protein 0.0075 0.0427 0.1614
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0075 0.0427 0.2044
Echinococcus multilocularis sex peptide receptor 0.0032 0.0134 0.0134
Echinococcus granulosus snurportin 1 0.0332 0.2174 0.2174
Trypanosoma brucei ISWI complex protein 0.0022 0.0067 0.0262
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0134 0.0134
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0085 0.0493 0.1865
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0287 0.0287
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi thymidylate kinase 0.007 0.0396 0.9364
Brugia malayi steroid hormone receptor 0.0013 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0067 0.0371 0.1404
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trichomonas vaginalis ribonuclease H1, putative 0.0067 0.037 0.2878
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0134 0.0506
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0115 0.0435
Schistosoma mansoni high-affinity choline transporter 0.0258 0.167 0.167
Brugia malayi chromobox protein homolog 3 0.0029 0.0114 0.043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.002 0.0155
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0402 0.2644 1
Schistosoma mansoni opsin-like receptor 0.0032 0.0134 0.0134
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0034 0.0265
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0023 0.007 0.007
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0067 0.0371 0.1404
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0011 0.0043
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0013 0.0006 0.0006
Loa Loa (eye worm) thymidylate kinase 0.007 0.0396 0.0396
Schistosoma mansoni hypothetical protein 0.0032 0.0134 0.0134
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0098 0.0761
Onchocerca volvulus 0.0027 0.0102 0.0956
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0085 0.0493 0.1343
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0017 0.0034 0.0034
Chlamydia trachomatis thymidylate kinase 0.007 0.0396 0.9215
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0134 0.0134
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.003 0.012 0.012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0045 0.0045
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0134 0.0134
Echinococcus multilocularis thioredoxin glutathione reductase 0.0026 0.0094 0.0094
Echinococcus multilocularis tar DNA binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni ap endonuclease 0.0014 0.0015 0.0015
Echinococcus multilocularis serotonin receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0287 0.0287
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.015 0.015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0222 0.1064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0128 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Treponema pallidum ribonuclease H (rnhA) 0.0067 0.037 0.8729
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0031 0.0314
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0067 0.0371 0.1404
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0134 0.0134
Trypanosoma brucei PAB1-binding protein , putative 0.0068 0.0375 0.1462
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0134 0.0134
Brugia malayi prolyl oligopeptidase family protein 0.0067 0.0374 0.1413
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0134 0.0134
Schistosoma mansoni sodium/solute symporter 0.0028 0.011 0.011
Onchocerca volvulus 0.0085 0.0493 0.4946
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0017 0.0034 0.0034
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0031 0.0031
Toxoplasma gondii aldehyde dehydrogenase 0.0041 0.0198 0.2003
Echinococcus granulosus dnaJ subfamily B 0.0208 0.1331 0.1331
Echinococcus granulosus thioredoxin glutathione reductase 0.0026 0.0094 0.0094
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0031 0.0031
Onchocerca volvulus 0.0032 0.0134 0.1279
Toxoplasma gondii ion channel protein 0.0067 0.0371 0.3755
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.0015 0.0072
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0008 0.0008
Brugia malayi glutathione reductase 0.0026 0.0092 0.0348
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0944 0.4523
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0026 0.0092 0.0225
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0134 0.0134
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0011 0.027
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0017 0.0034 0.0034
Loa Loa (eye worm) beta-lactamase 0.0085 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0222 0.1064
Brugia malayi neuropeptide F receptor 0.0032 0.0134 0.0506
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0134 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0493 0.2363
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0008 0.0008
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0158 0.0989 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Mycobacterium ulcerans deoxycytidine triphosphate deaminase 0.0026 0.0092 0.0633
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0085 0.0493 0.0493
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0134 0.0134
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Entamoeba histolytica hypothetical protein 0.0017 0.0031 0.0737
Brugia malayi Glycosyl hydrolases family 31 protein 0.012 0.0732 0.2768
Brugia malayi Heterochromatin protein 1 0.0052 0.0268 0.1014
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Echinococcus granulosus dUTP pyrophosphatase 0.0074 0.0421 0.0421
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0011
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0158 0.0989 0.2724
Treponema pallidum thymidylate kinase (tmk) 0.007 0.0396 0.9364
Leishmania major thymidylate kinase-like protein 0.007 0.0396 0.1895
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Entamoeba histolytica hypothetical protein 0.0026 0.0092 0.2184
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0011 0.0043
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0088 0.0688
Trichomonas vaginalis thymidylate kinase, putative 0.007 0.0396 0.3079
Echinococcus multilocularis lysosomal alpha glucosidase 0.012 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0198 0.1467
Echinococcus granulosus expressed protein 0.0035 0.0153 0.0153
Mycobacterium tuberculosis Conserved protein 0.0085 0.0493 0.1343
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0035 0.0155 0.15
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0005 0.0005
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0134 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0886
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0067 0.0371 0.0371
Toxoplasma gondii ribonuclease HI protein 0.0067 0.037 0.374
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0034 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.2087 1
Schistosoma mansoni ran 0.0013 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni phosphoglucomutase 0.0067 0.037 0.037
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis lysosomal alpha glucosidase 0.012 0.0732 0.0732
Brugia malayi Serotonin receptor 0.0032 0.0134 0.0506
Echinococcus multilocularis ferritin 0.0035 0.0153 0.0153
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0153 0.0394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0095 0.0095
Brugia malayi Pre-SET motif family protein 0.0127 0.0781 0.2955
Brugia malayi hypothetical protein 0.0067 0.0371 0.1404
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Brugia malayi Dopamine receptor 0.0032 0.0134 0.0506
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0134 0.0134
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0017 0.0034 0.0034
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.0015 0.0057
Echinococcus granulosus twik family of potassium channels 0.0067 0.0371 0.0371
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0008 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0015 0.0116
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Schistosoma mansoni amine GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni cpg binding protein 0.0034 0.0148 0.0148
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0008 0.0032
Schistosoma mansoni zinc finger protein 0.003 0.0121 0.0121
Trichomonas vaginalis sucrase-isomaltase, putative 0.0027 0.0098 0.0761
Schistosoma mansoni phosphoglucomutase 0.0067 0.037 0.037
Mycobacterium tuberculosis Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) 0.0026 0.0092 0.0225
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0088 0.0423
Echinococcus granulosus neuropeptide receptor 0.0032 0.0134 0.0134
Toxoplasma gondii thymidylate kinase 0.007 0.0396 0.4
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0088 0.0516 0.0516
Schistosoma mansoni cpg binding protein 0.0034 0.0148 0.0148
Entamoeba histolytica acyl-CoA synthetase, putative 0.0014 0.0011 0.027
Schistosoma mansoni opsin-like receptor 0.0032 0.0134 0.0134
Entamoeba histolytica Thymidylate kinase, putative 0.007 0.0396 0.9386
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0134 0.0134
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0019 0.0045 0.0045
Brugia malayi intermediate filament protein 0.0054 0.0287 0.1084
Trypanosoma cruzi thymidylate kinase, putative 0.007 0.0396 0.1895
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0493 0.384
Brugia malayi Dopamine receptor protein 2 0.0032 0.0134 0.0506
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0022 0.0068 0.1625
Plasmodium falciparum ataxin-2 like protein, putative 0.0068 0.0375 0.3757
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0134 0.0134
Schistosoma mansoni amine GPCR 0.0032 0.0134 0.0134
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0134 0.0134
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0085 0.0085
Schistosoma mansoni neuropeptide receptor 0.0032 0.0134 0.0134
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0017 0.0034 0.0265
Mycobacterium leprae PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE) 0.0026 0.0092 0.0825
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0074 0.0421 1
Plasmodium falciparum thymidylate kinase 0.007 0.0396 0.3962
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0402 0.2644 0.2644
Onchocerca volvulus 0.0067 0.0371 0.3702
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0008 0.0032
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0134 0.1279
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0013 0.0006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0059 0.0316 0.085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trypanosoma cruzi ion transport protein, putative 0.0067 0.0371 0.1779
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0402 0.2644 0.2644
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0212 0.0212
Trypanosoma brucei thymidylate kinase, putative 0.007 0.0396 0.154
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0008 0.0008
Brugia malayi Dopamine receptor protein 1 0.0032 0.0134 0.0506
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0028 0.011 0.1114
Onchocerca volvulus 0.0032 0.0134 0.1279
Echinococcus multilocularis lamin 0.0054 0.0287 0.0287
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0035 0.0153 0.3387
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0008 0.0032
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0035 0.0155 0.0155
Loa Loa (eye worm) thioredoxin reductase 0.0026 0.0092 0.0092
Trypanosoma cruzi ISWI complex protein 0.0022 0.0067 0.0323
Brugia malayi hypothetical protein 0.0017 0.0034 0.0129
Brugia malayi nuclear hormone receptor 0.0013 0.0008 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0134 0.0134
Brugia malayi larval opioid receptor 0.0032 0.0134 0.0506
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0493 0.384
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0134 0.0134
Brugia malayi hypothetical protein 0.015 0.0938 0.3548
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0074 0.0421 0.4225
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0134 0.0134
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0006 0.003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0088 0.0516 0.0516
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0067 0.0371 0.1404
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0134 0.0134
Loa Loa (eye worm) dUTP diphosphatase 0.0074 0.0421 0.0421
Onchocerca volvulus 0.0017 0.0034 0.0261
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.002 0.0155
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.0015 0.0072
Leishmania major ribonuclease H1, putative 0.0067 0.037 0.1771
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0008 0.0032
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0134 0.0134
Onchocerca volvulus 0.0067 0.0371 0.3702
Plasmodium vivax thymidylate kinase, putative 0.007 0.0396 0.3962
Brugia malayi beta-lactamase family protein 0.0085 0.0493 0.1865
Entamoeba histolytica hypothetical protein 0.0022 0.0068 0.1625
Brugia malayi RNase H family protein 0.0067 0.037 0.1398
Giardia lamblia Ribonuclease H 0.0067 0.037 0.9348
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi RNA recognition motif domain containing protein 0.0044 0.0214 0.081
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Toxoplasma gondii ion channel protein 0.0067 0.0371 0.3755
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Onchocerca volvulus 0.0032 0.0134 0.1279
Loa Loa (eye worm) hypothetical protein 0.0155 0.097 0.097
Loa Loa (eye worm) hypothetical protein 0.0155 0.097 0.097
Echinococcus granulosus methyl CpG binding domain protein 2 0.0025 0.0085 0.0085
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0098 0.037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0402 0.2644 0.2644
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0017 0.0034 0.0034
Trypanosoma brucei unspecified product 0.0076 0.043 0.1673
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.015 0.015
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0067 0.0371 0.1003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi putative neuropeptide receptor 0.0032 0.0134 0.0506
Echinococcus multilocularis cpg binding protein 0.0034 0.0148 0.0148
Brugia malayi dUTP diphosphatase 0.0074 0.0421 0.1594
Loa Loa (eye worm) RNA binding protein 0.0044 0.0214 0.0214
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0134 0.0134
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.0015 0.0015
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0013 0.0006 0.0025
Onchocerca volvulus 0.0014 0.0011 0.003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0008 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0134 0.0134
Brugia malayi Thioredoxin reductase 0.0026 0.0092 0.0348
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0028 0.0105 0.0502
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0134 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0023 0.007 0.007
Onchocerca volvulus 0.0035 0.0155 0.15
Mycobacterium ulcerans esterase/lipase LipP 0.0085 0.0493 0.3785
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0067 0.0374 0.3726
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0214 0.0214
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1415 0.9526 0.9526
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0067 0.0371 0.1404
Leishmania major importin beta-1 subunit, putative 0.0025 0.0088 0.0423
Brugia malayi PHD-finger family protein 0.0038 0.0173 0.0656
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0134 0.0506
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0008 0.0032
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0022 0.0068 0.0068
Echinococcus granulosus sex peptide receptor 0.0032 0.0134 0.0134
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, putative 0.0026 0.0092 0.2184
Schistosoma mansoni neuropeptide receptor 0.0032 0.0134 0.0134
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0128 0.1298
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0008 0.0032
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0371 0.289
Echinococcus granulosus ribonuclease H1 0.0067 0.037 0.037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0063 0.0348 0.0348
Trichomonas vaginalis ferritin, putative 0.0035 0.0153 0.1188
Echinococcus multilocularis twik family of potassium channels 0.0067 0.0371 0.0371
Treponema pallidum deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) 0.0074 0.0421 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0402 0.2644 0.2644
Loa Loa (eye worm) hypothetical protein 0.0044 0.0212 0.0212
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0085 0.0493 0.1343
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi hypothetical protein 0.0044 0.0213 0.0805
Schistosoma mansoni histamine h1 receptor 0.0032 0.0134 0.0134
Entamoeba histolytica hypothetical protein 0.0049 0.0246 0.5843
Onchocerca volvulus 0.0032 0.0134 0.1279
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0493 0.384
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0017 0.0034 0.0034
Trypanosoma brucei trypanothione reductase 0.0026 0.0092 0.0358
Loa Loa (eye worm) hypothetical protein 0.0068 0.0375 0.0375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0008 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0014 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0153 0.1445
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0134 0.0134
Plasmodium falciparum potassium channel 0.0067 0.0371 0.3715
Schistosoma mansoni alpha glucosidase 0.0027 0.0098 0.0098
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0115 0.0115
Schistosoma mansoni ferritin 0.0035 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.007 0.0396 0.3931
Mycobacterium tuberculosis Probable oxidoreductase 0.0065 0.0361 0.0975
Trypanosoma brucei ingi protein (ORF1) 0.0076 0.043 0.1673
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0041 0.0198 0.0198
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0134 0.0134
Onchocerca volvulus 0.0032 0.0134 0.1279
Onchocerca volvulus Ribonuclease H1 homolog 0.0067 0.037 0.3686
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0067 0.0371 0.1404
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0006 0.003
Schistosoma mansoni hypothetical protein 0.0332 0.2174 0.2174
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0008 0.0008
Brugia malayi RNA binding protein 0.0044 0.0214 0.081
Onchocerca volvulus 0.0032 0.0134 0.1279
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0067 0.0371 0.0371
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0022 0.0067 0.0067
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0134 0.0134
Mycobacterium tuberculosis Probable esterase LipL 0.0085 0.0493 0.1343
Echinococcus granulosus g protein coupled receptor 0.0032 0.0134 0.0134
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Echinococcus multilocularis SAM and MBT domain containing protein 0.0035 0.0155 0.0155
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0134 0.0134
Brugia malayi CXXC zinc finger family protein 0.003 0.0118 0.0447
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0155
Echinococcus granulosus cpg binding protein 0.0034 0.0148 0.0148
Brugia malayi neuropeptide F receptor 0.0032 0.0134 0.0506
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0005 0.0005
Brugia malayi RNA, U transporter 1 0.0089 0.0518 0.196
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0067 0.0371 0.0371
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0008 0.0008
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0067 0.0371 0.0371
Onchocerca volvulus 0.0067 0.0371 0.3702
Mycobacterium tuberculosis Conserved protein 0.0085 0.0493 0.1343
Echinococcus multilocularis microtubule associated protein 2 0.0411 0.271 0.271
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0067 0.0371 0.1404
Echinococcus multilocularis tumor protein p63 0.0423 0.2787 0.2787
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis dnaJ subfamily B 0.0208 0.1331 0.1331
Schistosoma mansoni inositol transporter 0.0028 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0134 0.0134
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0052 0.027 0.027
Echinococcus granulosus potassium channel subfamily K 8 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0067 0.0371 0.0371
Plasmodium vivax ataxin-2 like protein, putative 0.0068 0.0375 0.3757
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0074 0.0421 1
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Echinococcus granulosus muscleblind protein 0.0155 0.097 0.097
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0268 0.2088
Onchocerca volvulus 0.0067 0.0371 0.3702
Loa Loa (eye worm) glutaminase 2 0.0201 0.1284 0.1284
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0017 0.0034 0.0034
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0059 0.0316 0.085
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0134 0.0134
Onchocerca volvulus 0.0067 0.0371 0.3702
Loa Loa (eye worm) PHD-finger family protein 0.003 0.012 0.012
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0134 0.0506
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0028 0.0105 0.0502
Schistosoma mansoni zinc finger protein 0.0022 0.0067 0.0067
Echinococcus granulosus importin subunit beta 1 0.0031 0.0128 0.0128
Mycobacterium tuberculosis Conserved protein 0.0085 0.0493 0.1343
Leishmania major GTP-binding protein, putative 0.0013 0.0006 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0493 0.0493
Trypanosoma cruzi PAB1-binding protein , putative 0.0068 0.0375 0.1798
Schistosoma mansoni ferritin light chain 0.0035 0.0153 0.0153
Schistosoma mansoni sex comb on midleg homolog 0.0035 0.0155 0.0155
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0332 0.2174 0.2174
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0208 0.1331 0.1331
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0023 0.007 0.0337
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0065 0.0361 0.0975
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0008 0.0008
Echinococcus granulosus solute carrier family 5 0.0028 0.011 0.011
Echinococcus multilocularis potassium channel subfamily K 8 0.0067 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Schistosoma mansoni phosphoglucomutase 0.0067 0.037 0.037
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0134 0.0134
Brugia malayi G-protein coupled receptor 0.0032 0.0134 0.0506
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Brugia malayi latrophilin 2 splice variant baaae 0.0025 0.0087 0.033
Schistosoma mansoni amine GPCR 0.0032 0.0134 0.0134
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0034 0.0129
Giardia lamblia CDC8 0.007 0.0396 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0134 0.0134
Plasmodium falciparum ataxin-2 like protein, putative 0.0068 0.0375 0.3757
Echinococcus granulosus sodium:glucose cotransporter 0.0028 0.011 0.011
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0618 0.411 0.411
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0886
Brugia malayi hypothetical protein 0.0068 0.0375 0.142
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.0015 0.0058
Echinococcus granulosus g protein coupled receptor 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0371 0.0371
Leishmania major hypothetical protein, conserved 0.0068 0.0375 0.1798
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0028 0.011 0.011
Loa Loa (eye worm) glutathione reductase 0.0026 0.0092 0.0092
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0031 0.0121
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.0015 0.0028
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0134 0.0134
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0034 0.0129
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0402 0.2644 0.2644
Schistosoma mansoni twik family of potassium channels-related 0.0067 0.0371 0.0371
Entamoeba histolytica hypothetical protein 0.0025 0.0088 0.2096
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0017 0.0034 0.0265
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0118 0.0118
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0067 0.0371 0.1404
Schistosoma mansoni cpg binding protein 0.003 0.0118 0.0118
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0348 0.0348
Echinococcus multilocularis beta LACTamase domain containing family member 0.0085 0.0493 0.0493
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.002 0.0155
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0065 0.0361 0.0975
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0134 0.0134
Echinococcus multilocularis muscleblind protein 0.0155 0.097 0.097
Echinococcus multilocularis dUTP pyrophosphatase 0.0074 0.0421 0.0421
Echinococcus multilocularis expressed protein 0.0017 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0134 0.0134
Brugia malayi glutaminase DH11.1 0.0201 0.1284 0.4858
Brugia malayi hypothetical protein 0.0022 0.0068 0.0259
Echinococcus multilocularis neutral alpha glucosidase AB 0.0027 0.0098 0.0098
Echinococcus granulosus potassium channel subfamily K 0.0067 0.0371 0.0371
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0067 0.0371 0.1779
Schistosoma mansoni calcium-activated potassium channel 0.0067 0.0371 0.0371
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0129 0.1227
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0008 0.0008
Toxoplasma gondii ABC1 family protein 0.0085 0.0493 0.4989
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Schistosoma mansoni amine GPCR 0.0032 0.0134 0.0134
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0085 0.0493 0.1343
Brugia malayi GH02984p 0.0258 0.167 0.6315
Schistosoma mansoni cellular tumor antigen P53 0.0062 0.0337 0.0337
Echinococcus granulosus lysosomal alpha glucosidase 0.012 0.0732 0.0732
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0092 0.0441
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0542 0.3599 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0005
Brugia malayi nuclear receptor NHR-88 0.0013 0.0008 0.0032
Trichomonas vaginalis set domain proteins, putative 0.0145 0.09 0.7007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0041 0.0198 0.0949
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.0032 0.0134 0.0134
Plasmodium vivax thioredoxin reductase, putative 0.0026 0.0092 0.0873
Echinococcus multilocularis zinc finger protein 0.003 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0032 0.0134 0.0134
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0371 0.289
Onchocerca volvulus 0.0085 0.0493 0.4946
Schistosoma mansoni myelin transcription factor 1 myt1 0.004 0.0189 0.0189
Mycobacterium tuberculosis Hypothetical protein 0.0075 0.0427 0.1158
Brugia malayi hypothetical protein 0.0032 0.0134 0.0506
Entamoeba histolytica hypothetical protein 0.0074 0.0421 1

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 2.8 ug ml-1 Cytotoxicity against human HT-29 cells ChEMBL. 2778455
ED50 (functional) = 3.1 ug ml-1 Cytotoxicity against human A549 cells ChEMBL. 2778455
Mortality (functional) 0 Compound causing 100% mortality of Brugia malayi female adult worms at 3.125 ppm concentration; no mortality ChEMBL. 15828820
Mortality (functional) = 3 % Antifilarial activity of the compound against Microfilaria at 5 ppm in the first 5 days (100% mortality) ChEMBL. 15828820
Mortality (functional) = 5 % Antifilarial activity of the compound against Brugia malayi (female) at 5 ppm in the first 5 days (100% mortality) ChEMBL. 15828820
Mortality (functional) = 5 % Antifilarial activity of the compound against Brugia malayi (male) at 5 ppm in the first 5 days (100% mortality) ChEMBL. 15828820
Mortality (functional) = 5 % Antifilarial activity of the compound against Brugia malayi (female) at 5 ppm in the first 5 days (100% mortality) ChEMBL. 15828820
Mortality (functional) = 5 % Antifilarial activity of the compound against Brugia malayi (male) at 5 ppm in the first 5 days (100% mortality) ChEMBL. 15828820
Mortality (functional) = 2 day Compound causing 100% mortality of Brugia malayi female adult worms at 50 ppm concentration ChEMBL. 15828820
Mortality (functional) = 2 day Compound causing 100% mortality of Brugia malayi female adult worms at 50 ppm concentration ChEMBL. 15828820
Mortality (functional) = 3 day Compound causing 100% mortality of Brugia malayi female adult worms at 25 ppm concentration ChEMBL. 15828820
Mortality (functional) = 3 day Compound causing 100% mortality of Brugia malayi female adult worms at 25 ppm concentration ChEMBL. 15828820
Mortality (functional) = 4 day Compound causing 100% mortality of Brugia malayi female adult worms at 12.5 ppm concentration ChEMBL. 15828820
Mortality (functional) = 4 day Compound causing 100% mortality of Brugia malayi female adult worms at 12.5 ppm concentration ChEMBL. 15828820
Mortality (functional) = 5 day Compound causing 100% mortality of Brugia malayi female adult worms at 6.25 ppm concentration ChEMBL. 15828820
Mortality (functional) = 5 day Compound causing 100% mortality of Brugia malayi female adult worms at 6.25 ppm concentration ChEMBL. 15828820

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.