TDR Targets

Basic information

Technical information

TDR Targets ID: 333854
Name: 2-(3,5-dibromo-4-hexoxyphenyl)acetic acid
MW: 394.099 | Formula: C14H18Br2O3
H donors: 1 H acceptors: 2 LogP: 5.07 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: CCCCCCOc1c(Br)cc(cc1Br)CC(=O)O
InChi: 1S/C14H18Br2O3/c1-2-3-4-5-6-19-14-11(15)7-10(8-12(14)16)9-13(17)18/h7-8H,2-6,9H2,1H3,(H,17,18)
InChiKey: VJKVJESSSPWLJY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-(3,5-dibromo-4-hexoxy-phenyl)acetic acid
2-(3,5-dibromo-4-hexoxy-phenyl)ethanoic acid

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	thyroid hormone receptor, beta	Starlite/ChEMBL	References
Homo sapiens	thyroid hormone receptor, alpha	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	hypothetical protein	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma japonicum	Thyroid hormone receptor alpha, putative	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma mansoni	thyroid hormone receptor	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma japonicum	Thyroid hormone receptor alpha, putative	Get druggable targets OG5_134830	All targets in OG5_134830
Brugia malayi	Nuclear hormone receptor-like 1	Get druggable targets OG5_156853	All targets in OG5_156853
Brugia malayi	Nuclear hormone receptor-like 1	Get druggable targets OG5_156853	All targets in OG5_156853
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma japonicum	expressed protein	Get druggable targets OG5_134830	All targets in OG5_134830
Echinococcus multilocularis	thyroid hormone receptor alpha	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma mansoni	thyroid hormone receptor	Get druggable targets OG5_134830	All targets in OG5_134830
Schistosoma japonicum	ko:K08362 nuclear receptor, subfamily 1, group A, member 2, putative	Get druggable targets OG5_134830	All targets in OG5_134830
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	Get druggable targets OG5_134830	All targets in OG5_134830
Brugia malayi	Nuclear hormone receptor-like 1	Get druggable targets OG5_156853	All targets in OG5_156853
Loa Loa (eye worm)	nuclear hormone receptor-like 1	Get druggable targets OG5_156853	All targets in OG5_156853
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_156853	All targets in OG5_156853

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	photoreceptor-specific nuclear receptor	thyroid hormone receptor, beta	461 aa	414 aa	24.6 %
Brugia malayi	photoreceptor-specific nuclear receptor	thyroid hormone receptor, alpha	451 aa	372 aa	25.3 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Leishmania major	prostaglandin f2-alpha synthase/D-arabinose dehydrogenase	0.0378	0.4539	1
Onchocerca volvulus		0.0378	0.4539	1
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0024	0.0107	0.0237
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0024	0.0107	0.0237
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	0.0152	0.1708	0.1708
Trypanosoma cruzi	aldo-keto reductase	0.0378	0.4539	1
Plasmodium vivax	aldehyde reductase, putative	0.0109	0.1174	1
Trypanosoma cruzi	aldo/keto reductase, putative	0.0378	0.4539	1
Schistosoma mansoni	aldo-keto reductase	0.0378	0.4539	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Mycobacterium leprae	PROBABLE OXIDOREDUCTASE	0.0378	0.4539	1
Trypanosoma brucei	aldo-keto reductase, putative	0.0378	0.4539	1
Loa Loa (eye worm)	hypothetical protein	0.0378	0.4539	1
Schistosoma mansoni	retinoic acid receptor RXR	0.0024	0.0107	0.0237
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0024	0.0107	0.0237
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0378	0.4539	1
Plasmodium falciparum	aldehyde reductase, putative	0.0109	0.1174	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Toxoplasma gondii	aldo/keto reductase family oxidoreductase	0.0109	0.1174	0.2586
Echinococcus granulosus	aldo keto reductase	0.0378	0.4539	1
Toxoplasma gondii	aldose reductase, putative	0.0378	0.4539	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase	0.0378	0.4539	0.4539
Loa Loa (eye worm)	steroid hormone receptor	0.0024	0.0107	0.0237
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0024	0.0107	0.0237
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0024	0.0107	0.0237
Schistosoma mansoni	hypothetical protein	0.0152	0.1708	0.3763
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0024	0.0107	0.0237
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0024	0.0107	0.0237
Brugia malayi	NADH-dependent xylose reductase	0.0109	0.1174	0.2586
Schistosoma mansoni	nuclear hormone receptor	0.0024	0.0107	0.0237
Echinococcus granulosus	hypothetical protein	0.0378	0.4539	1
Schistosoma mansoni	RAR-like nuclear receptor	0.0024	0.0107	0.0237
Leishmania major	aldo/keto reductase, putative,aldo/keto reductase family-like protein	0.0109	0.1174	0.2586
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0378	0.4539	1
Plasmodium falciparum	aldo-keto reductase, putative	0.0109	0.1174	1
Loa Loa (eye worm)	oxidoreductase	0.0378	0.4539	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	Nuclear hormone receptor-like 1	0.0301	0.3574	0.7875
Onchocerca volvulus		0.0378	0.4539	1
Echinococcus granulosus	FTZ F1 alpha	0.0024	0.0107	0.0237
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0301	0.3574	0.7875
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Loa Loa (eye worm)	oxidoreductase	0.0378	0.4539	1
Echinococcus multilocularis	aldehyde reductase	0.0268	0.3167	0.3167
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Schistosoma mansoni	pol-related	0.0378	0.4539	1
Brugia malayi	glutamate-cysteine ligase modifier subunit	0.0109	0.1174	0.2586
Onchocerca volvulus		0.0378	0.4539	1
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0024	0.0107	0.0237
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0024	0.0107	0.0237
Mycobacterium ulcerans	oxidoreductase	0.0378	0.4539	1
Trypanosoma brucei	aldo/keto reductase, putative	0.0109	0.1174	0.2586
Echinococcus multilocularis	muscleblind protein 1	0.015	0.168	0.168
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	0.0152	0.1708	0.3763
Toxoplasma gondii	aldo-keto reductase	0.0109	0.1174	0.2586
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0024	0.0107	0.0237
Loa Loa (eye worm)	oxidoreductase	0.0378	0.4539	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor-like 1	0.0301	0.3574	0.7875
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0024	0.0107	0.0237
Trypanosoma brucei	prostaglandin f synthase	0.0378	0.4539	1
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0378	0.4539	1
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0176	0.2014	0.2014
Echinococcus granulosus	voltage gated potassium channel subunit	0.0109	0.1174	0.2586
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0024	0.0107	0.0237
Echinococcus multilocularis	muscleblind protein	0.015	0.168	0.168
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0024	0.0107	0.0237
Loa Loa (eye worm)	glutamate-cysteine ligase modifier subunit	0.0109	0.1174	0.2586
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0024	0.0107	0.0107
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0024	0.0107	0.0237
Loa Loa (eye worm)	oxidoreductase	0.0378	0.4539	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	ecdysteroid receptor	0.0024	0.0107	0.0237
Entamoeba histolytica	aldose reductase, putative	0.0378	0.4539	1
Giardia lamblia	Aldose reductase	0.0378	0.4539	0.5
Schistosoma mansoni	aldo-keto reductase	0.0378	0.4539	1
Schistosoma mansoni	potassium channel beta	0.0109	0.1174	0.2586
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Onchocerca volvulus		0.0378	0.4539	1
Brugia malayi	Steroid receptor seven-up type 2	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.015	0.168	0.3701
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0024	0.0107	0.0237
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Brugia malayi	photoreceptor-specific nuclear receptor	0.0024	0.0107	0.0237
Echinococcus granulosus	ecdysone induced protein 78C	0.0024	0.0107	0.0237
Onchocerca volvulus		0.0378	0.4539	1
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0378	0.4539	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0378	0.4539	1
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0024	0.0107	0.0237
Trichomonas vaginalis	aldo/keto reductase, putative	0.0378	0.4539	1
Trichomonas vaginalis	aldo/keto reductase, putative	0.0378	0.4539	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0024	0.0107	0.0237
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	nuclear receptor NHR-88	0.0024	0.0107	0.0237
Plasmodium vivax	oxidoreductase, aldo/keto reductase domain containing protein	0.0109	0.1174	1
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0378	0.4539	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0024	0.0107	0.0107
Loa Loa (eye worm)	oxidoreductase	0.0378	0.4539	1
Echinococcus granulosus	aldehyde reductase	0.0268	0.3167	0.6977
Giardia lamblia	Aldose reductase	0.0378	0.4539	0.5
Onchocerca volvulus		0.0109	0.1174	0.2406
Echinococcus multilocularis	ecdysone induced protein 78C	0.0024	0.0107	0.0107
Echinococcus multilocularis	aldo keto reductase	0.0378	0.4539	0.4539
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0024	0.0107	0.0237
Leishmania major	prostaglandin f synthase, putative	0.0378	0.4539	1
Brugia malayi	steroid hormone receptor	0.0024	0.0107	0.0237
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Brugia malayi	oxidoreductase, aldo/keto reductase family protein	0.0378	0.4539	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0312	0.3719	0.8193
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0024	0.0107	0.0107
Echinococcus granulosus	aldo keto reductase	0.0378	0.4539	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.015	0.168	0.3701
Leishmania major	aldehyde reductase, putative,oxidoreductase, putative	0.0378	0.4539	1
Echinococcus granulosus	muscleblind protein	0.015	0.168	0.3701
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0024	0.0107	0.0237
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0024	0.0107	0.0107
Toxoplasma gondii	oxidoreductase, aldo/keto reductase family protein	0.0109	0.1174	0.2586
Schistosoma mansoni	thyroid hormone receptor	0.0176	0.2014	0.4437
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0024	0.0107	0.0107
Echinococcus granulosus	aldo keto reductase family 1, member B4	0.0109	0.1174	0.2586
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Schistosoma mansoni	thyroid hormone receptor	0.0176	0.2014	0.4437
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Trypanosoma cruzi	aldo/keto reductase, putative	0.0109	0.1174	0.2586
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Echinococcus multilocularis	FTZ F1 alpha	0.0024	0.0107	0.0107
Trichomonas vaginalis	aldo/keto reductase, putative	0.0378	0.4539	1
Schistosoma mansoni	coup transcription factor	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0299	0.3557	0.7837
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Mycobacterium leprae	Conserved hypothetical protein	0.0268	0.3167	0.5922
Echinococcus granulosus	aldo keto reductase family 1 member B4	0.0378	0.4539	1
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0024	0.0107	0.0107
Trichomonas vaginalis	aldo-keto reductase, putative	0.0378	0.4539	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase	0.0378	0.4539	0.4539
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0024	0.0107	0.0237
Entamoeba histolytica	aldose reductase, putative	0.0378	0.4539	1
Leishmania major	aldo-keto reductase-like protein	0.0378	0.4539	1
Echinococcus multilocularis	voltage gated potassium channel subunit	0.0109	0.1174	0.1174
Entamoeba histolytica	aldose reductase, putative	0.0378	0.4539	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase	0.0378	0.4539	0.4539
Brugia malayi	nuclear hormone receptor	0.0024	0.0107	0.0237
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0107	0.0237
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Echinococcus multilocularis	aldo keto reductase family 1, member B4	0.0378	0.4539	0.4539
Brugia malayi	Muscleblind-like protein	0.015	0.168	0.3701
Onchocerca volvulus		0.0378	0.4539	1
Mycobacterium tuberculosis	Conserved protein	0.0109	0.1174	0.2586
Echinococcus granulosus	aldo keto reductase	0.0378	0.4539	1
Trichomonas vaginalis	dihydrodiol dehydrogenase, putative	0.0378	0.4539	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0024	0.0107	0.0237
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0024	0.0107	0.0237

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 5.28	Inhibition of thyroid hormone receptor alpha (unknown origin)	ChEMBL.	17467994
IC50 (binding)	= 5.82	Inhibition of human thyroid hormone receptor beta 1	ChEMBL.	17524652
IC50 (binding)	= 5.82	Inhibition of thyroid hormone receptor beta (unknown origin)	ChEMBL.	17467994
IC50 (binding)	= 0.7 uM	Inhibitory activity of the compound against human TRAFalpha	ChEMBL.	15857115
IC50 (binding)	= 0.7 uM	Inhibitory activity of the compound against human TRAFalpha	ChEMBL.	15857115
IC50 (binding)	= 0.8 uM	Inhibitory activity of the compound against human TRAFbeta	ChEMBL.	15857115
IC50 (binding)	= 0.8 uM	Inhibitory activity of the compound against human TRAFbeta	ChEMBL.	15857115
IC50 (binding)	= 1.5 uM	Inhibitory activity against human Thyroid hormone receptor beta	ChEMBL.	15857115
IC50 (binding)	= 1.5 uM	Inhibitory activity against human Thyroid hormone receptor beta	ChEMBL.	15857115
IC50 (binding)	= 5.2 uM	Inhibitory activity against human Thyroid hormone receptor alpha	ChEMBL.	15857115
IC50 (binding)	= 5.2 uM	Inhibitory activity against human Thyroid hormone receptor alpha	ChEMBL.	15857115
Log IC50 (binding)	= 5.28	Inhibition of thyroid hormone receptor alpha (unknown origin)	ChEMBL.	17467994
Log IC50 (binding)	= 5.82	Inhibition of human thyroid hormone receptor beta 1	ChEMBL.	17524652
Log IC50 (binding)	= 5.82	Inhibition of thyroid hormone receptor beta (unknown origin)	ChEMBL.	17467994

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL192639
PubChem: 11153607

Bibliographic References

3 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 333854