Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0619 | 0.1218 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0778 | 0.0773 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0778 | 0.9492 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0009 | 0.0068 | 0.0061 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0013 | 0.016 | 0.1068 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0041 | 0.0792 | 0.6371 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0042 | 0.0809 | 0.1596 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0068 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1916 | 0.1911 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.016 | 0.1068 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0277 | 0.0539 |
Schistosoma mansoni | apoptosis regulator bax | 0.0091 | 0.1916 | 0.1911 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0575 | 0.1131 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.016 | 0.1068 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0042 | 0.0809 | 0.1596 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.016 | 0.0307 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.0792 | 0.5436 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0111 | 0.0105 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0778 | 0.1535 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0029 | 0.0509 | 0.0885 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0778 | 0.1364 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0303 | 0.0589 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0042 | 0.0809 | 0.1596 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0303 | 0.3689 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0039 | 0.0751 | 0.0745 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0043 | 0.082 | 0.0814 |
Treponema pallidum | ATP-dependent DNA helicase | 0.0011 | 0.01 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0451 | 0.5501 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.01 | 0.0761 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0011 | 0.01 | 0.0649 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0451 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0036 | 0.0059 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0027 | 0.0464 | 0.0807 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0619 | 0.497 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0044 | 0.0851 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0778 | 0.1535 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.328 | 0.6508 |
Giardia lamblia | DINP protein human, muc B family | 0.0043 | 0.082 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0151 | 0.0145 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0029 | 0.0509 | 0.3479 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0008 | 0.0036 | 0.044 |
Plasmodium vivax | ATP-dependent DNA helicase Q1, putative | 0.001 | 0.0091 | 0.1125 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0504 | 0.099 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0008 | 0.0036 | 0.003 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.005 | 0.0987 | 0.1717 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0778 | 0.5344 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0008 | 0.0036 | 0.0063 |
Onchocerca volvulus | 0.0032 | 0.0575 | 0.0944 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0778 | 0.1364 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0008 | 0.0036 | 0.0063 |
Brugia malayi | Bloom's syndrome protein homolog | 0.005 | 0.0987 | 0.195 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0008 | 0.0036 | 0.044 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0279 | 0.0488 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0008 | 0.0036 | 0.0063 |
Mycobacterium leprae | conserved hypothetical protein | 0.0041 | 0.0778 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0033 | 0.0614 | 0.4933 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0036 | 0.0063 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0042 | 0.0809 | 0.9508 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0523 | 0.3578 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0008 | 0.0036 | 0.0059 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0042 | 0.0809 | 0.9863 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0778 | 0.9492 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0151 | 0.0145 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0008 | 0.0036 | 0.0368 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0111 | 0.0105 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0042 | 0.0809 | 0.5555 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0043 | 0.082 | 0.5632 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0778 | 0.1364 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0029 | 0.0509 | 0.0503 |
Plasmodium falciparum | flap endonuclease 1 | 0.0029 | 0.0509 | 0.5982 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0424 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0451 | 0.0885 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0778 | 0.1364 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0504 | 0.3445 |
Schistosoma mansoni | hypothetical protein | 0.045 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0043 | 0.082 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0451 | 0.0885 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0778 | 0.1364 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0575 | 0.1131 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0071 | 0.1451 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.1239 | 1 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0042 | 0.0809 | 0.5555 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0451 | 0.3079 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0619 | 0.0613 |
Onchocerca volvulus | 0.0041 | 0.0778 | 0.1299 | |
Leishmania major | DNA polymerase kappa, putative | 0.0013 | 0.016 | 0.1068 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0036 | 0.0059 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Schistosoma mansoni | DNA helicase recq5 | 0.0021 | 0.0327 | 0.0321 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0303 | 0.3556 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0008 | 0.0036 | 0.044 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0013 | 0.016 | 0.1251 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1451 | 0.2873 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0043 | 0.082 | 0.1618 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0778 | 0.0773 |
Brugia malayi | polk-prov protein | 0.0013 | 0.016 | 0.0307 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0042 | 0.0809 | 0.5555 |
Plasmodium vivax | exosome complex exonuclease RRP6, putative | 0.0006 | 0.0006 | 0.0076 |
Mycobacterium ulcerans | hypothetical protein | 0.0006 | 0.0006 | 0.0075 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0013 | 0.016 | 0.1068 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0042 | 0.0809 | 0.0803 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0778 | 0.9492 |
Brugia malayi | Flap endonuclease-1 | 0.0029 | 0.0509 | 0.0999 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0036 | 0.0207 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.016 | 0.1068 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0619 | 0.0613 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1916 | 0.1911 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0327 | 0.0639 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Loa Loa (eye worm) | oxidoreductase | 0.0008 | 0.0036 | 0.0059 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.0792 | 0.5436 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0029 | 0.0509 | 0.6291 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0091 | 0.1916 | 0.1911 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0091 | 0.1916 | 0.3796 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0008 | 0.0036 | 0.044 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0279 | 0.0488 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.023 | 0.5037 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0027 | 0.0464 | 0.3167 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0504 | 0.6231 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0616 | 0.061 |
Trypanosoma brucei | unspecified product | 0.0043 | 0.082 | 0.5632 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0576 | 0.057 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0042 | 0.0809 | 1 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0091 | 0.1916 | 0.1911 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0303 | 0.0589 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0451 | 0.0885 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0451 | 0.5501 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0036 | 0.0207 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0008 | 0.0036 | 0.0059 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0451 | 0.5501 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Entamoeba histolytica | recQ family helicase, putative | 0.001 | 0.0091 | 0.1043 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0778 | 0.1354 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0068 | 0.14 | 0.1395 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0042 | 0.0809 | 0.5555 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0327 | 0.0639 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0043 | 0.082 | 0.1426 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0036 | 0.0063 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0011 | 0.01 | 0.0094 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0027 | 0.0464 | 0.3167 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0043 | 0.082 | 0.1437 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0008 | 0.0036 | 0.0063 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0036 | 0.0063 |
Schistosoma mansoni | DNA helicase recq1 | 0.0021 | 0.0327 | 0.0321 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0091 | 0.1916 | 0.1911 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0778 | 0.1535 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0108 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1916 | 0.3796 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1916 | 0.1911 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0068 | 0.0061 |
Trichomonas vaginalis | set domain proteins, putative | 0.0262 | 0.5749 | 1 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0042 | 0.0809 | 0.0803 |
Echinococcus multilocularis | dna polymerase eta | 0.0071 | 0.1451 | 0.1446 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0091 | 0.1916 | 0.3796 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0303 | 0.0589 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0042 | 0.0809 | 0.1407 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.026 | 0.5708 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical alanine rich protein | 0.0006 | 0.0006 | 0.0011 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0008 | 0.0036 | 0.044 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0043 | 0.082 | 0.1618 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0778 | 0.1535 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0207 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0043 | 0.082 | 0.1426 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0021 | 0.0327 | 0.0321 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0036 | 0.0063 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0778 | 0.1364 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0619 | 0.0613 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0451 | 0.5501 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0523 | 0.3578 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0778 | 0.6263 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0451 | 0.5501 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0036 | 0.0207 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0778 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0303 | 0.0589 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0029 | 0.0509 | 0.4078 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Echinococcus multilocularis | dnaJ subfamily B | 0.045 | 1 | 1 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0042 | 0.0809 | 0.1407 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0778 | 0.5344 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0504 | 0.4038 |
Echinococcus granulosus | bloom syndrome protein | 0.005 | 0.0987 | 0.0982 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0619 | 0.0613 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0778 | 0.1364 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0303 | 0.0589 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0036 | 0.0059 |
Echinococcus multilocularis | bloom syndrome protein | 0.005 | 0.0987 | 0.0982 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0778 | 0.1354 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0042 | 0.0809 | 0.1596 |
Onchocerca volvulus | 0.0026 | 0.0451 | 0.0726 | |
Toxoplasma gondii | propionate-CoA ligase | 0.0008 | 0.0036 | 0.0243 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0008 | 0.0036 | 0.0388 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0036 | 0.0063 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0778 | 0.9492 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0451 | 0.3079 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0303 | 0.374 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0207 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0504 | 0.3445 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.01 | 0.0187 |
Entamoeba histolytica | Flap nuclease, putative | 0.0029 | 0.0509 | 0.6177 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0504 | 0.3445 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0451 | 0.5467 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0451 | 0.5501 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0778 | 0.1354 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0575 | 0.0569 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0008 | 0.0036 | 0.0063 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0013 | 0.016 | 0.1068 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0029 | 0.0509 | 0.5283 |
Loa Loa (eye worm) | RecQ helicase | 0.005 | 0.0987 | 0.195 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0327 | 0.0639 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0619 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0451 | 0.0885 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0008 | 0.0036 | 0.003 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0451 | 0.5501 |
Leishmania major | DNA polymerase eta, putative | 0.0071 | 0.1451 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0619 | 0.0613 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0207 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0007 | 0.0012 | 0.0021 |
Leishmania major | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0043 | 0.082 | 0.5632 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Mycobacterium leprae | Probable lipase LipE | 0.0041 | 0.0778 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0451 | 0.5467 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0071 | 0.1451 | 0.2873 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0021 | 0.0327 | 0.0321 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0451 | 0.5762 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0111 | 0.0208 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0303 | 0.053 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0504 | 0.5924 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0091 | 0.1916 | 0.1911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0006 | 0.0011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0778 | 0.1364 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Onchocerca volvulus | 0.0041 | 0.0778 | 0.1299 | |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0027 | 0.0464 | 0.3167 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0042 | 0.0809 | 0.6511 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0008 | 0.0036 | 0.0388 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0451 | 0.5501 |
Schistosoma mansoni | DNA polymerase eta | 0.0071 | 0.1451 | 0.1446 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0778 | 0.1535 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0008 | 0.0036 | 0.0243 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0013 | 0.016 | 0.1068 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0011 | 0.01 | 0.0649 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0778 | 0.9492 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0043 | 0.082 | 0.0814 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0068 | 0.0061 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0008 | 0.0036 | 0.0388 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0008 | 0.0036 | 0.0063 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0504 | 0.5924 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0013 | 0.016 | 0.1251 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0451 | 0.5467 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0523 | 0.3578 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0021 | 0.0327 | 0.0639 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0043 | 0.082 | 0.0814 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0778 | 0.1364 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0778 | 0.0773 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0451 | 0.3079 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0036 | 0.0063 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0029 | 0.0509 | 0.0999 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0207 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0451 | 0.079 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0451 | 0.5762 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0008 | 0.0036 | 0.0063 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0504 | 0.3445 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0025 | 0.0043 |
Schistosoma mansoni | flap endonuclease-1 | 0.0026 | 0.0447 | 0.0441 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Echinococcus granulosus | dna polymerase eta | 0.0071 | 0.1451 | 0.1446 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0013 | 0.016 | 0.0154 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0036 | 0.0207 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0043 | 0.082 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0778 | 0.1354 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0778 | 0.5344 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0151 | 0.0145 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0034 | 0.0623 | 0.7706 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0279 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0451 | 0.0885 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0778 | 0.1535 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0013 | 0.016 | 0.1885 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0008 | 0.0036 | 0.044 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0008 | 0.0036 | 0.0207 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0616 | 0.061 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0523 | 0.3578 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0013 | 0.016 | 0.1068 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0021 | 0.0327 | 0.2532 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0009 | 0.0068 | 0.0061 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0043 | 0.082 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0008 | 0.0036 | 0.003 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0279 | 0.0488 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0451 | 0.079 |
Leishmania major | DNA damage repair protein, putative | 0.0013 | 0.016 | 0.1068 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0008 | 0.0036 | 0.044 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0778 | 0.9623 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0013 | 0.016 | 0.1068 |
Entamoeba histolytica | recQ family helicase, putative | 0.0027 | 0.0464 | 0.5624 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0778 | 0.1364 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0778 | 0.1535 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Onchocerca volvulus | 0.0262 | 0.5749 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.023 | 0.5037 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0021 | 0.0327 | 0.3848 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0619 | 0.1218 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0778 | 0.0773 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0778 | 0.5344 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0021 | 0.0327 | 0.0321 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0616 | 0.061 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0327 | 0.2606 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0013 | 0.016 | 0.1068 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0043 | 0.082 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0025 | 0.0043 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0029 | 0.0509 | 0.3479 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0504 | 0.099 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0043 | 0.082 | 0.5632 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0091 | 0.1916 | 0.1911 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0042 | 0.0809 | 0.0803 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0523 | 0.3578 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0029 | 0.0509 | 0.3479 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0043 | 0.082 | 0.1437 |
Echinococcus granulosus | flap endonuclease 1 | 0.0029 | 0.0509 | 0.0503 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0008 | 0.0036 | 0.044 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0021 | 0.0327 | 0.0321 |
Onchocerca volvulus | 0.0034 | 0.0619 | 0.102 | |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0071 | 0.1451 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0619 | 0.7651 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0303 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0327 | 0.2606 |
Onchocerca volvulus | 0.0041 | 0.0778 | 0.1299 | |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0778 | 0.1354 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0619 | 0.0613 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.005 | 0.0987 | 0.1717 |
Echinococcus multilocularis | dna polymerase kappa | 0.0043 | 0.082 | 0.0814 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0013 | 0.016 | 0.1983 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0025 | 0.0043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.082 | 0.5632 |
Mycobacterium ulcerans | hypothetical protein | 0.0013 | 0.016 | 0.1956 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.016 | 0.1068 |
Entamoeba histolytica | recQ family DNA helicase | 0.0011 | 0.01 | 0.1153 |
Echinococcus granulosus | dna polymerase kappa | 0.0043 | 0.082 | 0.0814 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0616 | 0.061 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0043 | 0.082 | 0.5632 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0008 | 0.0036 | 0.0243 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Decrease (functional) | = 6 % | Vasorelaxant activity determined by percentage inhibition of calcium-induced contraction on K+ depolarized guinea pig aortic strip at 5x10E-5 M | ChEMBL. | 15801835 |
Decrease (functional) | = 11 % | Negative chronotropic activity was determined as percent decrease in the artial rate in spontaneously beating guinea pig artium at 5x10E-5 M (n=6-8) | ChEMBL. | 15801835 |
Decrease (functional) | = 79 % | Negative inotropic activity of the compound was determined as decrease in the developed tension in isolated guinea pig left artium at 10E-5 M (n=4-6) | ChEMBL. | 15801835 |
EC50 (functional) | = 0.31 uM | Negative inotropic potency of the compound was determined as decrease in the developed tension in isolated guinea pig left artium | ChEMBL. | 15801835 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.