Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | smad | 0.0025 | 0.0097 | 0.0138 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0097 | 0.0138 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.3183 | 0.6278 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0229 | 0.1501 | 0.8847 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0118 | 0.0636 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0229 | 0.1501 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0229 | 0.1501 | 0.2135 |
Schistosoma mansoni | thyroid hormone receptor | 0.0138 | 0.0877 | 0.1729 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0229 | 0.1501 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0107 | 0.0336 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0026 | 0.01 | 0.5 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0097 | 0.0304 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0078 | 0.0399 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0151 | 0.0512 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0249 | 0.0354 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0097 | 0.0304 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0151 | 0.0297 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0249 | 0.0491 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0249 | 0.0782 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0012 | 0.0038 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0226 | 0.148 | 0.4651 |
Brugia malayi | TAR-binding protein | 0.0473 | 0.3183 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0016 | 0.0033 | 0.0103 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0143 | 0.0282 |
Schistosoma mansoni | ferritin | 0.0026 | 0.01 | 0.0198 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.058 | 0.1823 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0229 | 0.1501 | 0.296 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0523 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0131 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0642 | 0.2017 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.045 | 0.1415 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0022 | 0.0069 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0128 | 0.0806 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0133 | 0.0419 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0277 | 0.0872 |
Mycobacterium leprae | Probable lipase LipE | 0.0229 | 0.1501 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0151 | 0.0474 |
Toxoplasma gondii | ABC1 family protein | 0.0229 | 0.1501 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0229 | 0.1501 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0097 | 0.0191 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0372 | 0.0734 |
Mycobacterium leprae | conserved hypothetical protein | 0.0229 | 0.1501 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.103 | 0.7029 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0131 | 0.0412 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0135 | 0.0735 |
Brugia malayi | beta-lactamase | 0.0229 | 0.1501 | 0.4715 |
Loa Loa (eye worm) | TAR-binding protein | 0.0473 | 0.3183 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0107 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Schistosoma mansoni | ran | 0.0022 | 0.0078 | 0.0154 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0151 | 0.0474 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0249 | 0.1472 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0142 | 0.0777 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0229 | 0.1501 | 0.296 |
Onchocerca volvulus | 0.0229 | 0.1501 | 0.8854 | |
Schistosoma mansoni | ferritin | 0.0026 | 0.01 | 0.0198 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0097 | 0.0138 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0249 | 0.1472 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0107 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0028 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0078 | 0.0111 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0133 | 0.2776 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0011 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0369 | 0.2467 | 0.7749 |
Onchocerca volvulus | 0.0027 | 0.0107 | 0.0626 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0229 | 0.1501 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0019 | 0.0061 |
Entamoeba histolytica | hypothetical protein | 0.0268 | 0.1772 | 1 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0078 | 0.0245 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0078 | 0.0309 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.0642 | 0.2017 |
Schistosoma mansoni | hypothetical protein | 0.0429 | 0.2879 | 0.5679 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.045 | 0.1415 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0097 | 0.0304 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0473 | 0.3183 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0151 | 0.0297 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0277 | 0.1667 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0011 | 0.0001 | 0.0001 |
Schistosoma mansoni | ran | 0.0022 | 0.0078 | 0.0154 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0229 | 0.1501 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0033 | 0.0046 |
Brugia malayi | beta-lactamase family protein | 0.0229 | 0.1501 | 0.4715 |
Brugia malayi | MH2 domain containing protein | 0.0011 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0097 | 0.0304 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.0806 | 0.159 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0107 | 0.0152 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0277 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0277 | 0.1402 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0107 | 0.0336 |
Trichomonas vaginalis | esterase, putative | 0.0229 | 0.1501 | 0.8847 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0133 | 0.0686 |
Schistosoma mansoni | lamin | 0.0027 | 0.0107 | 0.0211 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0033 | 0.0046 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.058 | 0.1145 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0249 | 0.1008 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0151 | 0.0215 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0033 | 0.0129 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0097 | 0.0304 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0038 | 0.0183 | 0.1021 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0151 | 0.0215 |
Trichomonas vaginalis | set domain proteins, putative | 0.0257 | 0.1695 | 1 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0107 | 0.0336 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0033 | 0.0129 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0078 | 0.0245 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0415 | 0.1303 |
Brugia malayi | hypothetical protein | 0.0268 | 0.1772 | 0.5568 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0107 | 0.0336 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.045 | 0.0641 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0229 | 0.1501 | 0.4715 |
Onchocerca volvulus | 0.0027 | 0.0107 | 0.0626 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.058 | 0.1145 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0011 | 0.0001 | 0.0003 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0078 | 0.0111 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0249 | 0.1008 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0133 | 0.0686 |
Loa Loa (eye worm) | beta-lactamase | 0.0229 | 0.1501 | 0.4715 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.01 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0369 | 0.2467 | 0.7749 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0151 | 0.0298 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.0642 | 0.2017 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0107 | 0.0152 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0019 | 0.0061 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0151 | 0.0215 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0151 | 0.0297 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0268 | 0.1772 | 0.2522 |
Schistosoma mansoni | ferritin | 0.0026 | 0.01 | 0.0198 |
Schistosoma mansoni | smad | 0.0011 | 0.0001 | 0.0002 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0097 | 0.0138 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0097 | 0.0138 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0094 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Giardia lamblia | GTOR | 0.0047 | 0.0249 | 0.0573 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0325 | 0.1736 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0143 | 0.0203 |
Brugia malayi | RNA binding protein | 0.0473 | 0.3183 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0746 | 0.5071 | 0.7214 |
Loa Loa (eye worm) | fli-1 protein | 0.0232 | 0.1523 | 0.4785 |
Loa Loa (eye worm) | RNA binding protein | 0.0473 | 0.3183 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0151 | 0.0298 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0038 | 0.0183 | 0.1021 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0131 | 0.0412 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0078 | 0.0309 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.0642 | 0.2017 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0229 | 0.1501 | 0.8847 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0229 | 0.1501 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0201 | 0.1131 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0082 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0104 | 0.0326 |
Schistosoma mansoni | ets-related | 0.0232 | 0.1523 | 0.3004 |
Echinococcus granulosus | tar DNA binding protein | 0.0473 | 0.3183 | 0.4529 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0094 | 0.0093 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0523 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0107 | 0.0211 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.0077 | 0.0305 |
Mycobacterium tuberculosis | Conserved protein | 0.0229 | 0.1501 | 0.1415 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0133 | 0.0389 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0746 | 0.5071 | 0.7214 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0097 | 0.0304 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0229 | 0.1501 | 0.1415 |
Brugia malayi | Fli-1 protein | 0.0232 | 0.1523 | 0.4785 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0229 | 0.1501 | 0.4715 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0151 | 0.0964 | 0.19 |
Echinococcus multilocularis | smad | 0.0025 | 0.0097 | 0.0138 |
Echinococcus granulosus | expressed protein | 0.0026 | 0.01 | 0.0143 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0415 | 0.0818 |
Schistosoma mansoni | hypothetical protein | 0.0268 | 0.1772 | 0.3495 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0019 | 0.0061 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0033 | 0.0129 |
Mycobacterium tuberculosis | Conserved protein | 0.0229 | 0.1501 | 0.1415 |
Schistosoma mansoni | smad | 0.0025 | 0.0097 | 0.0191 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.01 | 0.0198 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0097 | 0.0138 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0182 | 0.1018 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Loa Loa (eye worm) | nuclear factor I | 0.0014 | 0.0019 | 0.0061 |
Onchocerca volvulus | 0.0229 | 0.1501 | 0.8854 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0151 | 0.0474 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0229 | 0.1501 | 0.2135 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0249 | 0.1413 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0009 | 0.0028 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0128 | 0.0806 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0249 | 0.1472 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0151 | 0.0215 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0026 | 0.01 | 0.5 |
Onchocerca volvulus | 0.0257 | 0.1695 | 1 | |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0249 | 0.1472 |
Echinococcus multilocularis | expressed protein | 0.0026 | 0.01 | 0.0143 |
Entamoeba histolytica | hypothetical protein | 0.0268 | 0.1772 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0116 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0964 | 0.3027 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0082 | 0.0117 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0138 | 0.0196 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.0001 | 0.0002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0182 | 0.1018 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0525 |
Brugia malayi | beta-lactamase family protein | 0.0229 | 0.1501 | 0.4715 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0249 | 0.1413 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0229 | 0.1501 | 0.8847 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0097 | 0.0138 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0429 | 0.2879 | 0.4097 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.3183 | 0.6278 |
Onchocerca volvulus | 0.003 | 0.0131 | 0.0768 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Mycobacterium tuberculosis | Conserved protein | 0.0229 | 0.1501 | 0.1415 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0097 | 0.0191 |
Schistosoma mansoni | lamin | 0.0027 | 0.0107 | 0.0211 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0249 | 0.0354 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0277 | 0.1667 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0138 | 0.0877 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0151 | 0.0474 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.3183 | 0.6278 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0133 | 0.0389 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0229 | 0.1501 | 0.8847 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0133 | 0.0263 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0097 | 0.0304 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0011 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.045 | 0.1415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0011 | 0.0001 | 0.0001 |
Echinococcus granulosus | snurportin 1 | 0.0325 | 0.2163 | 0.3077 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0525 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0133 | 0.0419 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0229 | 0.1501 | 0.8847 |
Leishmania major | hypothetical protein, conserved | 0.0229 | 0.1501 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.3183 | 0.6278 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0151 | 0.0215 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0011 | 0.0001 | 0.0001 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.01 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1501 | 0.4715 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0249 | 0.0782 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.058 | 0.0826 |
Entamoeba histolytica | hypothetical protein | 0.0268 | 0.1772 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0151 | 0.0474 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0118 | 0.0636 |
Brugia malayi | Smad1 | 0.0025 | 0.0097 | 0.0304 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.002 | 0.0059 | 0.0177 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0151 | 0.0297 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.01 | 0.0198 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0325 | 0.2163 | 0.6795 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0151 | 0.0215 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0277 | 0.1667 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0229 | 0.1501 | 0.1415 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0097 | 0.0191 |
Mycobacterium ulcerans | beta-lactamase | 0.0229 | 0.1501 | 1 |
Echinococcus multilocularis | ferritin | 0.0026 | 0.01 | 0.0143 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.058 | 0.0826 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0078 | 0.0309 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0107 | 0.0152 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0133 | 0.019 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0523 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0001 | 0.0003 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0277 | 0.1402 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0268 | 0.1772 | 0.3495 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.045 | 0.0641 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.058 | 0.0826 |
Echinococcus granulosus | dnaJ subfamily B | 0.0429 | 0.2879 | 0.4097 |
Onchocerca volvulus | 0.0033 | 0.0151 | 0.0884 | |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0082 | 0.0162 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0012 | 0.0017 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0107 | 0.0152 |
Brugia malayi | RNA, U transporter 1 | 0.0086 | 0.052 | 0.1634 |
Echinococcus granulosus | ferritin | 0.0026 | 0.01 | 0.0143 |
Echinococcus multilocularis | tumor protein p63 | 0.103 | 0.7029 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0143 | 0.0282 |
Trichomonas vaginalis | ferritin, putative | 0.0026 | 0.01 | 0.0531 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0033 | 0.0129 |
Giardia lamblia | Deoxynucleoside kinase | 0.0455 | 0.3059 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0277 | 0.1667 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0097 | 0.0191 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.058 | 0.0826 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0016 | 0.0033 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0151 | 0.0298 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0097 | 0.0191 |
Schistosoma mansoni | ferritin | 0.0026 | 0.01 | 0.0198 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0249 | 0.1472 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0151 | 0.0298 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0016 | 0.0033 | 0.0103 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0033 | 0.0129 |
Schistosoma mansoni | tar DNA-binding protein | 0.0473 | 0.3183 | 0.6278 |
Plasmodium vivax | hypothetical protein, conserved | 0.0229 | 0.1501 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0143 | 0.0203 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0473 | 0.3183 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0229 | 0.1501 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0116 | 0.0624 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0151 | 0.0215 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0249 | 0.1413 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0038 | 0.0183 | 0.1021 |
Brugia malayi | MH2 domain containing protein | 0.0369 | 0.2467 | 0.7749 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0118 | 0.0636 |
Echinococcus multilocularis | snurportin 1 | 0.0325 | 0.2163 | 0.3077 |
Echinococcus multilocularis | tar DNA binding protein | 0.0473 | 0.3183 | 0.4529 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0182 | 0.1018 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0151 | 0.0215 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0229 | 0.1501 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0249 | 0.1472 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0182 | 0.1018 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0094 | 0.0416 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0022 | 0.0069 |
Schistosoma mansoni | thyroid hormone receptor | 0.0138 | 0.0877 | 0.1729 |
Brugia malayi | Pre-SET motif family protein | 0.0226 | 0.148 | 0.4651 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.058 | 0.1823 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0094 | 0.0492 |
Onchocerca volvulus | 0.0229 | 0.1501 | 0.8854 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0229 | 0.1501 | 0.1415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0525 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0229 | 0.1501 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0374 | 0.1175 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0094 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0277 | 0.0872 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.045 | 0.0888 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0011 | 0.0001 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 0.2163 | 0.4266 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0078 | 0.0309 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.058 | 0.1145 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0133 | 0.019 |
Echinococcus granulosus | lamin | 0.0027 | 0.0107 | 0.0152 |
Entamoeba histolytica | hypothetical protein | 0.0268 | 0.1772 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0415 | 0.1303 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0268 | 0.1772 | 0.2522 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0099 | 0.0525 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.0001 | 0.0002 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0229 | 0.1501 | 0.1415 |
Onchocerca volvulus | 0.0151 | 0.0964 | 0.5683 | |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0012 | 0.0017 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0746 | 0.5071 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0277 | 1 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.0165 | 0.0615 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0151 | 0.0474 |
Mycobacterium ulcerans | lipase LipD | 0.0229 | 0.1501 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0165 | 0.0918 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0151 | 0.0512 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0152 | 0.0478 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0182 | 0.1018 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0094 | 0.0492 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0151 | 0.0215 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.31 uM | Inhibitory concentration against herpes simplex virus type 2 thymidine kinase | ChEMBL. | 15916444 |
IC50 (binding) | = 5.7 uM | Inhibitory concentration against herpes simplex virus type 1 thymidine kinase | ChEMBL. | 15916444 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.