Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | thyroid hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.0308 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0036 | 0.0032 | 0.0032 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | thyroid hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0008 | 0 | 0.0064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0041 | 0.0038 | 0.0038 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0012 | 0.0005 | 0.0074 |
Onchocerca volvulus | 0.001 | 0.0003 | 0.0022 | |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0182 | 0.02 | 0.02 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0012 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | intermediate filament protein | 0.001 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0041 | 0.0038 | 0.003 |
Plasmodium vivax | SET domain protein, putative | 0.0014 | 0.0007 | 0.0013 |
Brugia malayi | mbt repeat family protein | 0.0036 | 0.0032 | 0.0032 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0037 | 0.0033 | 0.006 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0013 | 0.0006 | 0.0006 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0071 | 0.0073 | 0.0131 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0008 | 0 | 0.0064 |
Echinococcus granulosus | tar DNA binding protein | 0.0032 | 0.0028 | 0.0028 |
Echinococcus multilocularis | musashi | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0013 | 0.0006 | 0.0006 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0071 | 0.0073 | 0.053 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0046 | 0.0044 | 0.0079 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Brugia malayi | steroid hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0156 | 0.017 | 0.017 |
Trichomonas vaginalis | set domain proteins, putative | 0.0109 | 0.0116 | 0.18 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | intermediate filament protein | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0046 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0008 | 0.0000065488 | 0.0000065488 |
Schistosoma mansoni | tar DNA-binding protein | 0.0032 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | calpain A | 0.0027 | 0.0022 | 0.0022 |
Echinococcus granulosus | dihydrofolate reductase | 0.8741 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0027 | 0.0022 | 0.0022 |
Echinococcus multilocularis | snurportin 1 | 0.0156 | 0.017 | 0.017 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0021 | 0.0038 |
Trypanosoma brucei | oligopeptidase b | 0.0041 | 0.0038 | 0.0069 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0036 | 0.0032 | 0.0032 |
Schistosoma mansoni | lamin | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0048 | 0.0046 | 0.0046 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0013 | 0.0006 | 0.0006 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0046 | 0.0044 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0013 | 0.0006 | 0.0006 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0048 | 0.0046 | 0.0046 |
Brugia malayi | RNA, U transporter 1 | 0.0042 | 0.0039 | 0.0039 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0048 | 0.0046 | 0.0046 |
Schistosoma mansoni | importin beta-1 | 0.0015 | 0.0008 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0004 | 0.0007 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1203 | 0.1369 | 0.1369 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Onchocerca volvulus | 0.1203 | 0.1369 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0069 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Brugia malayi | nuclear hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0033 | 0.006 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0046 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | RNA binding protein | 0.0032 | 0.0028 | 0.0028 |
Toxoplasma gondii | kringle domain-containing protein | 0.0011 | 0.0004 | 0.0006 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0037 | 0.0033 | 0.006 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0015 | 0.0008 | 0.0008 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0012 | 0.0005 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0048 | 0.0046 | 0.0046 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0145 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0013 | 0.0006 | 0.0006 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0021 | 0.0329 |
Echinococcus granulosus | importin subunit beta 1 | 0.0015 | 0.0008 | 0.0008 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0036 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0026 | 0.0021 | 0.0021 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0182 | 0.02 | 0.02 |
Brugia malayi | calpain family protein 1 | 0.0026 | 0.0021 | 0.0021 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma cruzi | oligopeptidase b | 0.0041 | 0.0038 | 0.0069 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.8741 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0032 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0137 | 0.0148 | 0.0267 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0071 | 0.0073 | 0.0073 |
Brugia malayi | mbt repeat family protein | 0.0036 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0156 | 0.017 | 0.017 |
Echinococcus multilocularis | tar DNA binding protein | 0.0032 | 0.0028 | 0.0028 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0008 | 0.0008 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0021 | 0.0038 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0026 | 0.0021 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.4849 | 0.5543 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0021 | 0.0021 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0013 | 0.0006 | 0.0006 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0573 | 0.0647 | 0.0611 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0041 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0015 | 0.0009 | 0.0009 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0145 | 0.0157 | 0.0157 |
Brugia malayi | Bromodomain containing protein | 0.0056 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0073 | 0.0073 |
Echinococcus multilocularis | DNA dependent protein kinase catalytic subunit | 0.0111 | 0.0118 | 0.0118 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0026 | 0.0021 | 0.0021 |
Brugia malayi | ecdysteroid receptor | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0013 | 0.0006 | 0.0006 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0015 | 0.0008 | 0.0014 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0182 | 0.02 | 0.1461 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0041 | 0.0038 | 0.0069 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0096 | 0.0101 | 0.0101 |
Echinococcus granulosus | thymidylate synthase | 0.1203 | 0.1369 | 0.1369 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4849 | 0.5543 | 1 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0008 | 0 | 0.0001 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.4849 | 0.5543 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4849 | 0.5543 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.8741 | 1 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0008 | 0.0000065488 | 0.0000065488 |
Brugia malayi | hypothetical protein | 0.0573 | 0.0647 | 0.0647 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0048 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0052 | 0.0052 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0015 | 0.0008 | 0.0014 |
Schistosoma mansoni | dihydrofolate reductase | 0.8741 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0008 | 0.0000065488 | 0.0000065488 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0004 | 0.0004 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0041 | 0.0038 | 0.0069 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0137 | 0.0148 | 0.0148 |
Echinococcus granulosus | FTZ F1 alpha | 0.0178 | 0.0195 | 0.0195 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0012 | 0.0005 | 0.0074 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0018 | 0.0012 | 0.0012 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0026 | 0.0021 | 0.0021 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0008 | 0.0000065488 | 0.0000065488 |
Brugia malayi | Pre-SET motif family protein | 0.0096 | 0.0101 | 0.0101 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Echinococcus granulosus | geminin | 0.0276 | 0.0308 | 0.0308 |
Treponema pallidum | methylated-DNA-protein-cysteine S-methyltransferase (dat) | 0.0037 | 0.0033 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0036 | 0.0032 | 0.0032 |
Echinococcus multilocularis | thymidylate synthase | 0.1203 | 0.1369 | 0.1369 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.007 | 0.007 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0026 | 0.0021 | 0.4879 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0045 | 0.0043 | 0.0004 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0014 | 0.0007 | 0.0013 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0036 | 0.0032 | 0.0032 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0011 | 0.0004 | 0.0007 |
Echinococcus multilocularis | lamin | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0017 | 0.0011 | 0.0011 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0008 | 0.0000065488 | 0.0031 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0015 | 0.0008 | 0.0015 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0013 | 0.0006 | 0.0045 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0182 | 0.02 | 0.02 |
Loa Loa (eye worm) | thymidylate synthase | 0.1203 | 0.1369 | 0.1369 |
Trypanosoma cruzi | ISWI complex protein | 0.0011 | 0.0004 | 0.0008 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0046 | 0.0046 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0014 | 0.0007 | 0.0007 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0071 | 0.0073 | 0.0131 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0008 | 0.0000065488 | 0.0000065488 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0046 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0008 | 0.0000065488 | 0.0000065488 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Trypanosoma brucei | prolyl endopeptidase | 0.0071 | 0.0073 | 0.0131 |
Brugia malayi | Pre-SET motif family protein | 0.0014 | 0.0007 | 0.0007 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.4849 | 0.5543 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0036 | 0.0032 | 0.0032 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0045 | 0.0043 | 0.0043 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0071 | 0.0073 | 0.0073 |
Plasmodium falciparum | importin beta, putative | 0.0015 | 0.0008 | 0.0008 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.004 | 0.0037 | 0.0037 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0024 | 0.0024 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0005 | 0.2271 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.1203 | 0.1369 | 0.1336 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0008 | 0.0000065488 | 0.0031 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0014 | 0.0007 | 0.0007 |
Brugia malayi | Dihydrofolate reductase | 0.8741 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.8741 | 1 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0012 | 0.0005 | 0.0009 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0027 | 0.0022 | 0.0022 |
Trypanosoma brucei | ISWI complex protein | 0.0011 | 0.0004 | 0.0008 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0026 | 0.0021 | 0.0329 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0032 | 0.0028 | 0.0028 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0143 | 0.0155 | 0.0155 |
Onchocerca volvulus | 0.0014 | 0.0007 | 0.005 | |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.0021 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0219 | 0.0242 | 0.0242 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0017 | 0.0011 | 0.0011 |
Brugia malayi | intermediate filament protein | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0026 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0011 | 0.0004 | 0.0004 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0036 | 0.0032 | 0.0235 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0013 | 0.0006 | 0.0006 |
Mycobacterium ulcerans | thymidylate synthase | 0.1203 | 0.1369 | 0.1362 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0137 | 0.0148 | 0.0267 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Trichomonas vaginalis | importin beta-1, putative | 0.0012 | 0.0005 | 0.0074 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0137 | 0.0148 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0012 | 0.0012 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0697 | 0.0789 | 0.0789 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0046 | 0.0046 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0026 | 0.0021 | 0.0329 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0027 | 0.0022 | 0.0022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0 | 0.0001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.4849 | 0.5543 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0015 | 0.0008 | 0.0014 |
Brugia malayi | calpain family protein 1 | 0.0026 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0013 | 0.0006 | 0.0006 |
Onchocerca volvulus | 0.001 | 0.0003 | 0.0022 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0036 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0038 | 0.0038 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0026 | 0.0021 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0048 | 0.0046 | 0.0046 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.004 | 0.0037 | 0.0037 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0137 | 0.0148 | 0.0267 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0026 | 0.0021 | 0.0021 |
Brugia malayi | Protein kinase domain containing protein | 0.0011 | 0.0004 | 0.0004 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0573 | 0.0647 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.004 | 0.0037 | 0.0037 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0046 | 0.0044 | 0.0044 |
Echinococcus granulosus | snurportin 1 | 0.0156 | 0.017 | 0.017 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0012 | 0.0005 | 0.0009 |
Echinococcus granulosus | calpain A | 0.0027 | 0.0022 | 0.0022 |
Leishmania major | hypothetical protein, conserved | 0.0011 | 0.0004 | 0.0007 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0013 | 0.0006 | 0.0045 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0026 | 0.0021 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0026 | 0.0026 |
Onchocerca volvulus | 0.0018 | 0.0012 | 0.0086 | |
Echinococcus multilocularis | muscleblind protein 1 | 0.0048 | 0.0046 | 0.0046 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Mycobacterium tuberculosis | Methylated-DNA--protein-cysteine methyltransferase Ogt (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltra | 0.0112 | 0.012 | 0.0082 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0046 | 0.0044 | 0.0044 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0008 | 0.0000065488 | 0.0000065488 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0044 | 0.0044 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0026 | 0.0021 | 0.0021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0008 | 0.0000065488 | 0.0000065488 |
Brugia malayi | TAR-binding protein | 0.0032 | 0.0028 | 0.0028 |
Giardia lamblia | Serine peptidase, putative | 0.0008 | 0 | 0.0016 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | zinc finger protein | 0.0015 | 0.0008 | 0.0008 |
Trypanosoma cruzi | oligopeptidase b | 0.0041 | 0.0038 | 0.0069 |
Echinococcus multilocularis | muscleblind protein | 0.0048 | 0.0046 | 0.0046 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0026 | 0.0021 | 0.0021 |
Onchocerca volvulus | 0.0109 | 0.0116 | 0.085 | |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0008 | 0 | 0.0001 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0094 | 0.0099 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0028 | 0.0028 |
Leishmania major | oligopeptidase b | 0.0041 | 0.0038 | 0.0069 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0071 | 0.0073 | 0.0073 |
Chlamydia trachomatis | dihydrofolate reductase | 0.8741 | 1 | 1 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.004 | 0.0037 | 0.0037 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0145 | 0.0157 | 0.0157 |
Brugia malayi | Importin beta-1 subunit | 0.0015 | 0.0008 | 0.0008 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0182 | 0.02 | 0.02 |
Onchocerca volvulus | 0.0036 | 0.0032 | 0.0235 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | geminin | 0.0276 | 0.0308 | 0.0308 |
Schistosoma mansoni | bromodomain containing protein | 0.0048 | 0.0046 | 0.0046 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0041 | 0.0038 | 0.0038 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Plasmodium falciparum | peptidase, putative | 0.0026 | 0.0021 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0021 | 0.0021 |
Echinococcus multilocularis | zinc finger protein | 0.0015 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0046 | 0.0046 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0013 | 0.0006 | 0.0006 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0008 | 0 | 0.0001 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0137 | 0.0148 | 0.0267 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0027 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0021 | 0.0021 |
Schistosoma mansoni | tar DNA-binding protein | 0.0032 | 0.0028 | 0.0028 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0027 | 0.0022 | 0.0022 |
Giardia lamblia | Thymus-specific serine protease precursor | 0.0008 | 0 | 0.0016 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0026 | 0.0021 | 0.0021 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0041 | 0.0038 | 0.0069 |
Schistosoma mansoni | tar DNA-binding protein | 0.0032 | 0.0028 | 0.0028 |
Onchocerca volvulus | 0.0011 | 0.0004 | 0.0025 | |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0037 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | muscleblind protein | 0.0048 | 0.0046 | 0.0046 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0036 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0012 | 0.0012 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0018 | 0.0012 | 0.0012 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0027 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | TAR-binding protein | 0.0032 | 0.0028 | 0.0028 |
Echinococcus multilocularis | lamin dm0 | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0143 | 0.0155 | 0.0155 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0137 | 0.0148 | 0.0148 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0071 | 0.0073 | 0.0073 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0024 | 0.0024 |
Brugia malayi | thymidylate synthase | 0.1203 | 0.1369 | 0.1369 |
Toxoplasma gondii | prolyl endopeptidase | 0.0071 | 0.0073 | 0.0131 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0036 | 0.0032 | 0.0032 |
Brugia malayi | RNA binding protein | 0.0032 | 0.0028 | 0.0028 |
Schistosoma mansoni | zinc finger protein | 0.0011 | 0.0004 | 0.0004 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0573 | 0.0647 | 0.1167 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0026 | 0.0021 | 0.0021 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0036 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0009 | 0.0009 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.0008 | 0 | 0.0001 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0041 | 0.0038 | 0.0038 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0041 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0036 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.0308 | 0.0308 |
Mycobacterium ulcerans | methylated-DNA--protein-cysteine methyltransferase Ogt | 0.0112 | 0.012 | 0.0111 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0013 | 0.0006 | 0.0045 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0008 | 0.0000065488 | 0.0000065488 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0013 | 0.0006 | 0.0006 |
Brugia malayi | nuclear receptor NHR-88 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0182 | 0.02 | 0.02 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0008 | 0 | 0.0064 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0137 | 0.0148 | 0.0148 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0036 | 0.0032 | 0.0032 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0137 | 0.0148 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0013 | 0.0006 | 0.0006 |
Schistosoma mansoni | tar DNA-binding protein | 0.0032 | 0.0028 | 0.0028 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0026 | 0.0021 | 0.4879 |
Trypanosoma brucei | Alpha/beta hydrolase domain-containing protein | 0.0026 | 0.0021 | 0.0038 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0006 | 0.0006 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0026 | 0.0021 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | lamin | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | lamin dm0 | 0.001 | 0.0003 | 0.0003 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0026 | 0.0021 | 1 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0011 | 0.0004 | 0.0004 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.1203 | 0.1369 | 0.1336 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0013 | 0.0006 | 0.0006 |
Trichomonas vaginalis | methylated-DNA--protein-cysteine methyltransferase, putative | 0.0037 | 0.0033 | 0.0516 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0036 | 0.0032 | 0.0032 |
Echinococcus granulosus | DNA dependent protein kinase catalytic subunit | 0.0111 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | MBCTL1 | 0.0041 | 0.0038 | 0.0038 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0014 | 0.0007 | 0.0007 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0041 | 0.0038 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0041 | 0.0038 | 0.0069 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0008 | 0.0000065488 | 0.0000065488 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0026 | 0.0021 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Kringle domain containing protein | 0.0011 | 0.0004 | 0.0004 |
Trypanosoma cruzi | ISWI complex protein | 0.0011 | 0.0004 | 0.0008 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0036 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0032 | 0.0028 | 0.0028 |
Onchocerca volvulus | 0.0013 | 0.0006 | 0.0045 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | prolyl endopeptidase | 0.0071 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0013 | 0.0006 | 0.0006 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0015 | 0.0008 | 0.0014 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0021 | 0.0038 |
Mycobacterium leprae | PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA | 0.0112 | 0.012 | 0.0082 |
Schistosoma mansoni | coup transcription factor | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0048 | 0.0046 | 0.0046 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0013 | 0.0006 | 0.0006 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0013 | 0.0006 | 0.0006 |
Leishmania major | hypothetical protein, conserved | 0.0011 | 0.0004 | 0.0008 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0041 | 0.0038 | 0.0069 |
Echinococcus granulosus | lamin | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0045 | 0.0043 | 0.0043 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0026 | 0.0021 | 0.0038 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.8741 | 1 | 1 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.8741 | 1 | 1 |
Brugia malayi | PHD-finger family protein | 0.0019 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0004 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.045 uM | Inhibitory concentration of the compound against wild type human immunodeficiency virus | ChEMBL. | 15837308 |
IC50 (functional) | = 0.91 uM | Inhibitory concentration of the compound against resistant (A17) human immunodeficiency virus | ChEMBL. | 15837308 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.