Detailed information for compound 343192

Basic information

Technical information
  • TDR Targets ID: 343192
  • Name: phenyl(phosphonato)methanol
  • MW: 186.102 | Formula: C7H7O4P--
  • H donors: 1 H acceptors: 4 LogP: -0.82 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(P(=O)([O-])[O-])c1ccccc1
  • InChi: 1S/C7H9O4P/c8-7(12(9,10)11)6-4-2-1-3-5-6/h1-5,7-8H,(H2,9,10,11)/p-2
  • InChiKey: YLVXPXINUWURSG-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

  • phenyl-phosphonatomethanol
  • phenyl-phosphonato-methanol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0211 0.196 0.1944
Schistosoma mansoni neuropeptide receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0393 0.0386
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0151 0.0151
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0022 0.0086 0.0079
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0181 0.0181
Onchocerca volvulus 0.0319 0.3026 0.7121
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0056 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0063 0.0486 0.0486
Echinococcus multilocularis neurogenic locus protein delta 0.0022 0.0086 0.0079
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0591 0.0585
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0359 0.034
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi heat shock protein 90 0.0032 0.0181 0.0181
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.1666 0.1666
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0058 0.0437 0.0428
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Brugia malayi sulfakinin receptor protein 0.0023 0.0089 0.0089
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0022 0.0086 0.0086
Schistosoma mansoni loxhd1 0.002 0.0059 0.0052
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0601 0.0601
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0211 0.1963 0.1947
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0121 0.1066 0.1066
Onchocerca volvulus 0.0267 0.251 0.5906
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0448 0.4315 0.4304
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.041 0.0403
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0567 0.0561
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.1666 0.1661
Brugia malayi Cadherin domain containing protein 0.0022 0.0086 0.0086
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0089 0.0082
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0086 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0211 0.1963 0.1868
Onchocerca volvulus 0.0023 0.0089 0.0209
Mycobacterium ulcerans lipase LipD 0.0071 0.0567 0.0456
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0442 0.0442
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.019 0.1752 0.1735
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0089 0.0089
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0601 0.0594
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0337 0.0337
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0337 0.0331
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0431 0.0318
Loa Loa (eye worm) doublecortin family protein 0.002 0.0059 0.0059
Leishmania major hypothetical protein, conserved 0.005 0.0359 0.0359
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0089 0.0089
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0152 0.1368 0.1368
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0089 0.0089
Brugia malayi Trypsin-like protease protein 5 0.0056 0.0423 0.0423
Echinococcus multilocularis Mastin 0.0056 0.0423 0.0417
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0089 0.0082
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0132 0.0125
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0567 0.0456
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0296 0.0289
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0181 0.0181
Schistosoma mansoni myosin xvIII 0.0023 0.0089 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Echinococcus granulosus slit 2 protein 0.0022 0.0086 0.0079
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0089 0.0082
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.6685 0.6682
Onchocerca volvulus Putative cubilin 0.0022 0.0086 0.0202
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0089 0.0082
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0229 0.0229
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0601 1
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0172 0.1568 0.1563
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0442 0.4249 0.4245
Echinococcus multilocularis notch 0.0022 0.0086 0.0079
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0567 0.0456
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0152 0.0152
Schistosoma mansoni gabp alpha 0.0073 0.0591 0.0585
Brugia malayi hypothetical protein 0.002 0.0059 0.0059
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0086 0.0086
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0121 0.1066 0.106
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0151 0.0142
Schistosoma mansoni polycystin 1-related 0.002 0.0059 0.0052
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Echinococcus multilocularis tissue type plasminogen activator 0.0211 0.196 0.1955
Brugia malayi Dopamine receptor 0.0023 0.0089 0.0089
Onchocerca volvulus 0.0023 0.0089 0.0209
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0181 0.1858
Brugia malayi Protein kinase domain containing protein 0.0211 0.196 0.196
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Plasmodium falciparum thioredoxin reductase 0.0083 0.0692 0.0673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0601 0.0601
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0368 0.0368
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0117 0.0117
Echinococcus multilocularis somatostatin receptor 0.0023 0.0089 0.0082
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.002 0.0011
Brugia malayi Bromodomain containing protein 0.0043 0.0291 0.0291
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.1021 1 1
Brugia malayi Dopamine receptor protein 2 0.0023 0.0089 0.0089
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi neuropeptide F receptor 0.0023 0.0089 0.0089
Onchocerca volvulus 0.0071 0.0567 0.1335
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0442 0.0442
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1042 0.1042
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.013 0.1153 0.1049
Onchocerca volvulus 0.0442 0.4249 1
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0089 0.0082
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0601 0.0601
Echinococcus multilocularis muscleblind protein 1 0.0146 0.1309 0.1303
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi Melatonin receptor type 1A 0.0023 0.0089 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0229 0.0229
Trichomonas vaginalis adenosylhomocysteinase, putative 0.1021 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.1666 0.1661
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Schistosoma mansoni lipoxygenase 0.0055 0.041 0.0403
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0546 0.0539
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0264 0.0258
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0359 0.035
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0059 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.019 0.1752 0.1735
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0601 0.0601
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0089 0.0082
Brugia malayi Doublecortin family protein 0.002 0.0059 0.0059
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0089 0.0089
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0442 0.0442
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0203 0.0196
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0296 0.0296
Schistosoma mansoni hypothetical protein 0.0512 0.4947 0.4944
Brugia malayi GnHR receptor homolog 0.0023 0.0089 0.0089
Entamoeba histolytica hypothetical protein 0.0178 0.1627 0.1627
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.151 0.151
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Toxoplasma gondii ABC1 family protein 0.0071 0.0567 0.0559
Echinococcus multilocularis neurogenic locus notch protein 4 0.0022 0.0086 0.0079
Brugia malayi G protein-coupled receptor 0.0023 0.0089 0.0089
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0089 0.0082
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0567 0.0567
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0442 1
Schistosoma mansoni alpha-glucosidase 0.0143 0.1281 0.1275
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0058 0.0437 0.0437
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0089 0.0082
Trypanosoma brucei trypanothione reductase 0.0083 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0058 0.0437 0.0431
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0567 0.0567
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0431 0.0318
Onchocerca volvulus 0.0022 0.0086 0.0202
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0151 0.0034
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0359 0.0359
Plasmodium falciparum adenosylhomocysteinase 0.1021 1 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0172 0.1568 0.1568
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0601 0.0594
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0567 0.0561
Brugia malayi hypothetical protein 0.0056 0.0423 0.0423
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Schistosoma mansoni adenosylhomocysteinase 0.0632 0.6136 0.6134
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0368 0.0368
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0567 0.0567
Echinococcus multilocularis cpg binding protein 0.0033 0.019 0.0183
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Brugia malayi Bromodomain containing protein 0.0086 0.0716 0.0716
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0567 0.0549
Echinococcus granulosus protein jagged 2 0.0022 0.0086 0.0079
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0567 0.0549
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0103 0.0891 0.0885
Echinococcus multilocularis geminin 0.0512 0.4947 0.4944
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0203 0.0196
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0151 0.0151
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0089 0.0082
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0172 0.1568 0.1563
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.004 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0059 0.0059
Trypanosoma brucei glucosidase, putative 0.0037 0.0229 0.0229
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0117 0.0117
Entamoeba histolytica hypothetical protein 0.0178 0.1627 0.1627
Leishmania major hypothetical protein, conserved 0.0211 0.196 0.196
Brugia malayi MAP kinase sur-1 0.0051 0.0368 0.0368
Onchocerca volvulus 0.0056 0.0423 0.0996
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0146 0.1309 0.1309
Echinococcus multilocularis heat shock protein 90 0.0025 0.0117 0.011
Brugia malayi Cadherin domain containing protein 0.0022 0.0086 0.0086
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0337 0.0337
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0591 0.0585
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Onchocerca volvulus 0.0023 0.0089 0.0209
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Loa Loa (eye worm) TK/ROR protein kinase 0.0211 0.196 0.196
Onchocerca volvulus 0.0071 0.0567 0.1335
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0319 0.3026 0.3012
Loa Loa (eye worm) hypothetical protein 0.0211 0.196 0.196
Mycobacterium tuberculosis Hypothetical protein 0.0152 0.1368 0.1351
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0089 0.0082
Onchocerca volvulus 0.0023 0.0089 0.0209
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0368 0.0368
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0061 0.0061
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0181 0.0181
Onchocerca volvulus 0.0096 0.0816 0.1921
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0058 0.0437 0.0437
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0007 0.0007
Echinococcus multilocularis neurogenic locus protein delta 0.0022 0.0086 0.0079
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.1021 1 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0891 0.0885
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0891 0.0885
Onchocerca volvulus 0.0022 0.0086 0.0202
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium tuberculosis Probable dehydrogenase 0.019 0.1752 0.1735
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0368 0.0368
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Schistosoma mansoni alpha glucosidase 0.0037 0.0229 0.0223
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0089 0.0082
Echinococcus granulosus adenosylhomocysteinase 0.1021 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0089 0.0082
Brugia malayi Kringle domain containing protein 0.0211 0.196 0.196
Brugia malayi MH2 domain containing protein 0.0119 0.1042 0.1042
Echinococcus granulosus somatostatin receptor 0.0023 0.0089 0.0082
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0181 0.0181
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.1066 0.096
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0807 0.7879 0.7877
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Echinococcus granulosus dnaJ subfamily B 0.0413 0.3964 0.396
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.0692 0.0673
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.196 0.196
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0089 0.0089
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.1021 1 1
Brugia malayi glutathione reductase 0.0083 0.0692 0.0692
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Trichomonas vaginalis adenosylhomocysteinase, putative 0.1021 1 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0046 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.1666 0.1661
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0089 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1042 0.1042
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0229 0.0229
Schistosoma mansoni bromodomain containing protein 0.0073 0.0585 0.0579
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0117 0.0097
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.1666 0.1661
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0144
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0601 0.0594
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.151 0.1504
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0089 0.0082
Onchocerca volvulus 0.0211 0.196 0.4613
Echinococcus multilocularis GPCR, family 2 0.0048 0.0337 0.0331
Mycobacterium ulcerans O-succinylbenzoate synthase 0.0066 0.0515 0.0403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0089 0.0082
Brugia malayi prolyl oligopeptidase family protein 0.0172 0.1568 0.1568
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0264 0.0258
Schistosoma mansoni heat shock protein 0.0032 0.0181 0.0175
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0442 0.0442
Schistosoma mansoni hypothetical protein 0.0211 0.196 0.1955
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.1368 0.1368
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0891 0.0885
Onchocerca volvulus 0.0385 0.369 0.8684
Schistosoma mansoni neuropeptide receptor 0.0023 0.0089 0.0082
Trichomonas vaginalis endoplasmin, putative 0.002 0.0059 0.0059
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0368 0.0368
Echinococcus granulosus neurogenic locus notch protein 0.0022 0.0086 0.0079
Echinococcus multilocularis enteropeptidase 0.0056 0.0423 0.0417
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2189 0.2189
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0089 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0151 0.0131
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0075 0.0075
Schistosoma mansoni adenosylhomocysteinase 0.1021 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Echinococcus granulosus RUN 0.002 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi hypothetical protein 0.005 0.0359 0.0359
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0229 0.0229
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0601 0.0594
Schistosoma mansoni opsin-like receptor 0.0023 0.0089 0.0082
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0448 0.0439
Brugia malayi Thioredoxin reductase 0.0083 0.0692 0.0692
Echinococcus granulosus neuropeptide receptor 0.0023 0.0089 0.0082
Onchocerca volvulus 0.0023 0.0089 0.0209
Echinococcus granulosus neurogenic locus notch protein 0.0022 0.0086 0.0079
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.0043 0.0291 0.0291
Schistosoma mansoni biogenic amine receptor 0.0023 0.0089 0.0082
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0089 0.0082
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Onchocerca volvulus 0.002 0.0059 0.0138
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0151 0.0142
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0089 0.0089
Brugia malayi Muscle positioning protein 4 0.0022 0.0086 0.0086
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0368 0.5473
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0089 0.0082
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0056 0.0423 0.0417
Onchocerca volvulus 0.0023 0.0089 0.0209
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0151 0.0151
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0089 0.0082
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0442 0.0442
Echinococcus granulosus endoplasmin 0.0025 0.0117 0.011
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0368 0.0361
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0089 0.0082
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0181 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Mycobacterium tuberculosis Conserved protein 0.0071 0.0567 0.0549
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0359 0.0359
Echinococcus multilocularis serotonin receptor 0.0023 0.0089 0.0082
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.002 0.0059 0.0052
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0184 0.0178
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.151 0.1504
Schistosoma mansoni adenoreceptor 0.0023 0.0089 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Echinococcus multilocularis neuropeptide receptor A26 0.0945 0.9247 0.9246
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0442 0.0423
Loa Loa (eye worm) hypothetical protein 0.005 0.0356 0.0356
Schistosoma mansoni rab6-interacting 0.002 0.0059 0.0052
Loa Loa (eye worm) fli-1 protein 0.0222 0.2072 0.2072
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0329 0.0322
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0048 0.0337 0.0337
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0181 0.0181
Schistosoma mansoni zinc finger protein 0.0024 0.0098 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0368 0.0368
Echinococcus granulosus heat shock protein 0.0032 0.0181 0.0175
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0229 0.0229
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0181 0.0181
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.019 0.1752 0.1735
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0601 0.0594
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.1021 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0089 0.0082
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0151 0.0151
Echinococcus multilocularis serotonin receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0393 0.0386
Brugia malayi Pre-SET motif family protein 0.0234 0.2189 0.2189
Loa Loa (eye worm) hypothetical protein 0.0442 0.4249 0.4249
Echinococcus granulosus tissue type plasminogen activator 0.0211 0.196 0.1955
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0089 0.0082
Echinococcus granulosus Mastin 0.0056 0.0423 0.0417
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.1021 1 1
Echinococcus multilocularis glycoprotein Antigen 5 0.0056 0.0423 0.0417
Echinococcus multilocularis protein jagged 2 0.0022 0.0086 0.0079
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0089 0.0082
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.0696 0.069
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0448 0.4315 0.4315
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0117 0.0117
Schistosoma mansoni laminin gamma-3 chain 0.0022 0.0086 0.0079
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0567 0.0549
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Schistosoma mansoni cpg binding protein 0.0033 0.019 0.0183
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0368 0.0368
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0089 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0059 0.0039
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0172 0.1568 0.3691
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Echinococcus granulosus g protein coupled receptor 0.0023 0.0089 0.0082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0453 0.4358 0.4347
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Echinococcus granulosus transmembrane protease serine 3 0.0056 0.0423 0.0417
Echinococcus multilocularis transmembrane protease serine 3 0.0056 0.0423 0.0417
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0442 0.6921
Plasmodium vivax endoplasmin, putative 0.0032 0.0181 0.0162
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.019 0.1752 0.1735
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Mycobacterium tuberculosis Probable oxidoreductase 0.0211 0.1963 0.1947
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Echinococcus multilocularis slit 2 protein 0.0022 0.0086 0.0079
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.002 0.002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0203 0.0194
Echinococcus granulosus enteropeptidase 0.0056 0.0423 0.0417
Echinococcus granulosus sex peptide receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0059 0.0052
Schistosoma mansoni ap endonuclease 0.0058 0.0442 0.0436
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) dihydrofolate reductase 0.013 0.1153 0.1153
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0172 0.1568 0.1563
Loa Loa (eye worm) hypothetical protein 0.0079 0.0652 0.0652
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Echinococcus multilocularis neural cadherin 0.0022 0.0086 0.0079
Echinococcus multilocularis thymidylate synthase 0.0319 0.3026 0.3021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0151 0.0151
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0601 0.0601
Plasmodium falciparum thioredoxin reductase 0.0029 0.0151 0.0131
Echinococcus granulosus notch 0.0022 0.0086 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0229 0.0229
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0567 0.0561
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0393 0.0386
Onchocerca volvulus 0.0023 0.0089 0.0209
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0296 0.0289
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0056 0.0423 0.0417
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0054 0.0047
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0601 0.0594
Entamoeba histolytica adenosylhomocysteinase, putative 0.1021 1 1
Echinococcus multilocularis adenosylhomocysteinase 0.1021 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0151
Echinococcus granulosus dihydrofolate reductase 0.013 0.1153 0.1147
Schistosoma mansoni amine GPCR 0.0023 0.0089 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0229 0.0229
Schistosoma mansoni rab6-interacting 0.002 0.0059 0.0052
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Onchocerca volvulus 0.002 0.0059 0.0138
Toxoplasma gondii melibiase subfamily protein 0.0103 0.0891 0.0882
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.004
Loa Loa (eye worm) adenosylhomocysteinase 0.1021 1 1
Brugia malayi Serotonin receptor 0.0023 0.0089 0.0089
Echinococcus multilocularis protein jagged 1 0.0022 0.0086 0.0079
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0448 0.4315 0.4315
Treponema pallidum NADH oxidase 0.0029 0.0151 0.1045
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0368 0.0361
Echinococcus granulosus delta-like protein 1 0.0022 0.0086 0.0079
Schistosoma mansoni ets-related 0.0222 0.2072 0.2067
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0567 0.0561
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Echinococcus granulosus fibropellin Ia 0.0022 0.0086 0.0079
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.1066 0.096
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0337 0.0331
Echinococcus granulosus zinc finger protein 0.0024 0.0098 0.0092
Echinococcus granulosus voltage gated potassium channel 0.0018 0.004 0.0033
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Brugia malayi hypothetical protein 0.0178 0.1627 0.1627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0089 0.0082
Brugia malayi Endoplasmin precursor 0.0032 0.0181 0.0181
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0089 0.0082
Brugia malayi Trypsin family protein 0.0056 0.0423 0.0423
Brugia malayi beta-lactamase family protein 0.0071 0.0567 0.0567
Onchocerca volvulus 0.0023 0.0089 0.0209
Brugia malayi isocitrate dehydrogenase 0.0016 0.002 0.002
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0089 0.0082
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0089 0.0082
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0359 0.034
Trichomonas vaginalis esterase, putative 0.0071 0.0567 0.0567
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0211 0.1963 0.1947
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0442 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.002 0.0013
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0056 0.0423 0.0417
Schistosoma mansoni hypothetical protein 0.0023 0.0089 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Mycobacterium ulcerans hypothetical protein 0.0071 0.0567 0.0456
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Echinococcus granulosus g protein coupled receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Echinococcus granulosus heat shock protein 90 0.0032 0.0181 0.0175
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.0423
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0151 0.0131
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0089 0.0082
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0181 0.0181
Schistosoma mansoni dihydrofolate reductase 0.013 0.1153 0.1147
Loa Loa (eye worm) hypothetical protein 0.0103 0.0886 0.0886
Schistosoma mansoni hypothetical protein 0.0103 0.0886 0.088
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0201 0.0201
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0229 0.0229
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Schistosoma mansoni cpg binding protein 0.0033 0.019 0.0183
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0114 0.0991 0.0991
Schistosoma mansoni neuropeptide receptor 0.0023 0.0089 0.0082
Schistosoma mansoni hypothetical protein 0.0023 0.0089 0.0082
Trypanosoma brucei protein kinase, putative 0.0051 0.0368 0.0368
Brugia malayi follicle stimulating hormone receptor 0.0476 0.4587 0.4587
Onchocerca volvulus 0.0056 0.0423 0.0996
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0567 0.0567
Brugia malayi dihydrofolate reductase family protein 0.013 0.1153 0.1153
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0448 0.4315 0.4315
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Onchocerca volvulus 0.0023 0.0089 0.0209
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0329 0.0322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.1666 0.1661
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0089 0.0082
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0181 0.0181
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0048 0.0337 0.0331
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0059 0.0052
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0117 0.0117
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0181 0.0162
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.002 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0393 0.0386
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0181 0.0181
Leishmania major S-adenosylhomocysteine hydrolase 0.1021 1 1
Echinococcus granulosus fmrfamide receptor 0.0023 0.0089 0.0082
Brugia malayi RE15519p 0.0023 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0413 0.3964 0.396
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0229 0.0229
Schistosoma mansoni amine GPCR 0.0023 0.0089 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0089 0.0082
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0442 0.0423
Schistosoma mansoni adenosylhomocysteinase 0.0632 0.6136 0.6134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0368 0.0359
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.002 0.0013
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0089 0.0089
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0059 0.0052
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0089 0.0082
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.002 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Echinococcus multilocularis neurogenic locus notch protein 0.0022 0.0086 0.0079
Echinococcus granulosus glycoprotein Antigen 5 0.0056 0.0423 0.0417
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0549 0.0542
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0114 0.0991 0.0985
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0144
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.002 0.002
Loa Loa (eye worm) trypsin family protein 0.0056 0.0423 0.0423
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0089 0.0082
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0117 0.0603
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.3964 0.396
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0368 0.0368
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0567 0.0567
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0089 0.0082
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0089 0.0082
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.1021 1 1
Schistosoma mansoni cell polarity protein 0.0022 0.0086 0.0079
Schistosoma mansoni histamine h1 receptor 0.0023 0.0089 0.0082
Schistosoma mansoni hypothetical protein 0.0048 0.0337 0.0331
Mycobacterium ulcerans thymidylate synthase 0.0319 0.3026 0.2944
Onchocerca volvulus Neurogenic locus notch homolog 0.0022 0.0086 0.0202
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0368 0.0368
Echinococcus multilocularis heat shock protein 0.0032 0.0181 0.0175
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Echinococcus multilocularis neuropeptide s receptor 0.0945 0.9247 0.9246
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0181 0.0172
Onchocerca volvulus 0.0034 0.0203 0.0477
Brugia malayi thymidylate synthase 0.0319 0.3026 0.3026
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0151 0.1045
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Brugia malayi putative neuropeptide receptor 0.0023 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0023 0.0089 0.0082
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0089 0.0082
Schistosoma mansoni amine GPCR 0.0023 0.0089 0.0082
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0089 0.0089
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0089 0.0089
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.0696 0.069
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.041 0.0403
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0567 0.0549
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Chlamydia trachomatis dihydrofolate reductase 0.013 0.1153 1
Schistosoma mansoni notch 0.0022 0.0086 0.0079
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0086 0.0086
Schistosoma mansoni endoplasmin 0.0032 0.0181 0.0175
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0151 0.0131
Echinococcus multilocularis sodium channel protein 0.0114 0.0991 0.0985
Echinococcus granulosus neurogenic locus protein delta 0.0022 0.0086 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0368 0.0361
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Plasmodium falciparum glutathione reductase 0.0029 0.0151 0.0131
Echinococcus granulosus neuropeptide receptor A26 0.0945 0.9247 0.9246
Loa Loa (eye worm) glutathione reductase 0.0083 0.0692 0.0692
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni biogenic amine receptor 0.0023 0.0089 0.0082
Schistosoma mansoni lipoxygenase 0.002 0.0059 0.0052
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0368 0.0361
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0359 0.034
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0117 0.0117
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0229 0.022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0151 0.1359 0.1359
Brugia malayi CXXC zinc finger family protein 0.0029 0.0152 0.0152
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0089 0.0082
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Brugia malayi Isocitrate dehydrogenase 0.0016 0.002 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0151
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0089 0.0089
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0442 0.0423
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0601 0.0594
Echinococcus granulosus g protein coupled receptor 0.0023 0.0089 0.0082
Toxoplasma gondii EGF family domain-containing protein 0.0022 0.0086 0.0077
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0089 0.0082
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0229 0.0229
Onchocerca volvulus 0.0023 0.0089 0.0209
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0229 0.0229
Brugia malayi Muscleblind-like protein 0.0146 0.1309 0.1309
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0178 0.1627 0.1622
Brugia malayi larval opioid receptor 0.0023 0.0089 0.0089
Echinococcus granulosus neuropeptide s receptor 0.0945 0.9247 0.9246
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0059 0.0052
Schistosoma mansoni opsin-like receptor 0.0023 0.0089 0.0082
Onchocerca volvulus 0.0056 0.0423 0.0996
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0017 0.0034 0.0028
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.0692 0.0673
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0229 0.0229
Echinococcus multilocularis protein jagged 1 0.0022 0.0086 0.0079
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0442 0.0442
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0181 0.0181
Trypanosoma cruzi ISWI complex protein 0.0017 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0058 0.0437 0.0437
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0891 0.0885
Trypanosoma brucei heat shock protein, putative 0.0032 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0229 0.0229
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0059 0.0039
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0229 0.0229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0089 0.0082
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis RUN 0.002 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Trichomonas vaginalis set domain proteins, putative 0.0267 0.251 0.251
Brugia malayi prolyl oligopeptidase family protein 0.0058 0.0437 0.0437
Loa Loa (eye worm) endoplasmin 0.0032 0.0181 0.0181
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0089 0.0082
Brugia malayi hypothetical protein 0.0032 0.0184 0.0184
Onchocerca volvulus 0.0023 0.0089 0.0209
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.0549 0.0549
Plasmodium falciparum cysteine repeat modular protein 1 0.0211 0.196 0.1944
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0567 0.0456
Entamoeba histolytica hypothetical protein 0.0178 0.1627 0.1627
Echinococcus granulosus geminin 0.0512 0.4947 0.4944
Brugia malayi hypothetical protein 0.0152 0.1368 0.1368
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0476 0.4587 0.4587
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0023 0.0094 0.0087
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.151 0.151
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.1359 0.1359
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni adenosylhomocysteinase 0.0632 0.6136 0.6134
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Schistosoma mansoni ap endonuclease 0.0058 0.0442 0.0436
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0054 0.0047
Loa Loa (eye worm) hypothetical protein 0.0069 0.0549 0.0549
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0103 0.0891 0.0885
Echinococcus granulosus sodium channel protein 0.0114 0.0991 0.0985
Echinococcus granulosus neural cadherin 0.0022 0.0086 0.0079
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.0692 0.0692
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.1359 0.1359
Onchocerca volvulus 0.0056 0.0423 0.0996
Brugia malayi Fli-1 protein 0.0222 0.2072 0.2072
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0103 0.0891 0.0885
Loa Loa (eye worm) hypothetical protein 0.0039 0.0248 0.0248
Onchocerca volvulus 0.0022 0.0086 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0089 0.0082
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0089 0.0089
Giardia lamblia Grp94/Hsp90 0.0025 0.0117 0.0603
Schistosoma mansoni adenosylhomocysteinase 0.0632 0.6136 0.6134
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.0692 0.0692
Echinococcus granulosus allatostatin A receptor 0.0023 0.0089 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0368 0.0368
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0089 0.0089
Echinococcus granulosus GPCR family 2 0.0048 0.0337 0.0331
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Mycobacterium tuberculosis Conserved protein 0.0071 0.0567 0.0549
Echinococcus granulosus protein jagged 2 0.0022 0.0086 0.0079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0601 0.0601
Onchocerca volvulus Slit protein homolog 0.0022 0.0086 0.0202
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.013 0.1153 0.1136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0567 0.0549
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0368 0.0361
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0442 0.0436
Brugia malayi notch-like transmembrane receptor 0.0022 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0431 0.0431
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0302 0.0302
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0058 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0229 0.0229
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0431 0.0425
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium tuberculosis Probable reductase 0.019 0.1752 0.1735
Entamoeba histolytica hypothetical protein 0.0178 0.1627 0.1627
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Echinococcus granulosus protein jagged 1 0.0022 0.0086 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium ulcerans beta-lactamase 0.0071 0.0567 0.0456
Echinococcus multilocularis dihydrofolate reductase 0.013 0.1153 0.1147
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.1666 0.1666
Brugia malayi Trypsin family protein 0.0056 0.0423 0.0423
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0089 0.0082
Schistosoma mansoni alpha-glucosidase 0.0143 0.1281 0.1275
Brugia malayi AKH receptor 0.0023 0.0089 0.0089
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni cpg binding protein 0.0029 0.0152 0.0145
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.0423
Echinococcus multilocularis endoplasmin 0.0025 0.0117 0.011
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0007 0.0007
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0337 0.0331
Schistosoma mansoni zinc finger protein 0.0017 0.0034 0.0028
Loa Loa (eye worm) beta-lactamase 0.0071 0.0567 0.0567
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0022 0.0086 0.0202
Schistosoma mansoni opsin-like receptor 0.0023 0.0089 0.0082
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.004 0.0033
Echinococcus granulosus neurogenic locus notch protein 4 0.0022 0.0086 0.0079
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0086
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0337 0.0331
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0319 0.3026 0.3021
Onchocerca volvulus 0.0022 0.0086 0.0202
Plasmodium falciparum endoplasmin, putative 0.002 0.0059 0.0039
Schistosoma mansoni endoplasmin 0.0032 0.0181 0.0175
Echinococcus granulosus cpg binding protein 0.0033 0.019 0.0183
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.002 0.0013
Echinococcus multilocularis heat shock protein 90 0.0032 0.0181 0.0175
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0567 0.0567
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0567 0.0567
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0056 0.0423 0.0417
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0567 0.0549
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0089 0.0082
Brugia malayi Trypsin family protein 0.0442 0.4249 0.4249
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.004 0.0033
Toxoplasma gondii kringle domain-containing protein 0.0211 0.196 0.1953
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.1666 0.1661
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0054 0.0047
Leishmania major hypothetical protein, conserved 0.0017 0.0034 0.0034
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0089 0.0082
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0442 0.4249 0.4245
Echinococcus multilocularis fibropellin Ia 0.0022 0.0086 0.0079
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0089 0.0082
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0089 0.0209
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0549 0.0542
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0567 0.0549
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.004 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0203 0.0196
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0431 0.0412
Schistosoma mansoni heat shock protein 0.0032 0.0181 0.0175
Schistosoma mansoni hypothetical protein 0.0056 0.0423 0.0417
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.1066 0.106
Toxoplasma gondii aldehyde dehydrogenase 0.0121 0.1066 0.1057
Schistosoma mansoni hypothetical protein 0.0056 0.0423 0.0417
Toxoplasma gondii adenosylhomocysteinase, putative 0.1021 1 1
Brugia malayi PHD-finger family protein 0.003 0.0158 0.0158
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.019 0.1752 0.1654
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0089 0.0082
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.013 0.1153 0.1049
Onchocerca volvulus 0.0022 0.0086 0.0202
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0048 0.0337 0.0331
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0442 0.0442
Plasmodium falciparum glutathione reductase 0.0083 0.0692 0.0673
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0181 0.0181
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.6685 0.6682
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0567 0.0567
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0368 0.0368
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Onchocerca volvulus 0.0023 0.0089 0.0209
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0074 0.0601 0.0601
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.1066 0.106
Brugia malayi Melibiase family protein 0.0069 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0071 0.0567 0.0567
Schistosoma mansoni biogenic amine receptor 0.0023 0.0089 0.0082
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0054 0.0047
Schistosoma mansoni hypothetical protein 0.0048 0.0337 0.0331
Loa Loa (eye worm) hypothetical protein 0.0146 0.1309 0.1309
Trypanosoma brucei ISWI complex protein 0.0017 0.0034 0.0034
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.1021 1 1
Schistosoma mansoni hypothetical protein 0.0178 0.1627 0.1622
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0144
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0442 0.0442
Brugia malayi ORL1-like opioid receptor 0.0023 0.0089 0.0089
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0229 0.0223
Plasmodium falciparum heat shock protein 90 0.0032 0.0181 0.0162
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0058 0.0437 0.0431
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Brugia malayi GCC2 and GCC3 family protein 0.0022 0.0086 0.0086
Brugia malayi Trypsin family protein 0.0056 0.0423 0.0423
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0089 0.0082
Brugia malayi Pre-SET motif family protein 0.0034 0.0203 0.0203
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0448 0.4315 0.4304
Schistosoma mansoni hypothetical protein 0.0023 0.0089 0.0082
Echinococcus multilocularis fat cadherin tumor suppressor 0.0022 0.0086 0.0079
Onchocerca volvulus 0.0056 0.0423 0.0996
Plasmodium vivax SET domain protein, putative 0.0034 0.0203 0.0183
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0151 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0089 0.0082
Schistosoma mansoni slit 0.0022 0.0086 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0089 0.0082
Echinococcus granulosus thymidylate synthase 0.0319 0.3026 0.3021
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0051 0.0051
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0591 0.0591
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0089 0.0209
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0059 0.0052
Echinococcus multilocularis neurogenic locus notch protein 0.0022 0.0086 0.0079
Brugia malayi Dihydrofolate reductase 0.013 0.1153 0.1153
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0601 0.0594
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Schistosoma mansoni amine GPCR 0.0023 0.0089 0.0082
Leishmania major trypanothione reductase 0.0083 0.0692 0.0692
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0359 0.0359
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0086 0.0079
Echinococcus granulosus Dipeptidyl peptidase 9 0.0058 0.0437 0.0431
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.002 0.002
Onchocerca volvulus 0.0023 0.0089 0.0209
Mycobacterium leprae Probable lipase LipE 0.0071 0.0567 0.0456
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0132 0.0125
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0132 0.0125
Echinococcus granulosus hypothetical protein 0.0023 0.0089 0.0082
Echinococcus granulosus serotonin receptor 0.0023 0.0089 0.0082
Echinococcus granulosus neuropeptide receptor 0.0023 0.0089 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.1066 0.096
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.002 0.0013
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0431 0.0425
Onchocerca volvulus 0.0071 0.0567 0.1335
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0151 0.0151
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0089 0.0082
Echinococcus granulosus protein jagged 1 0.0022 0.0086 0.0079
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0178 0.1627 0.1622
Loa Loa (eye worm) hypothetical protein 0.005 0.0359 0.0359
Echinococcus multilocularis zinc finger protein 0.0024 0.0098 0.0092
Leishmania major hypothetical protein, conserved 0.0071 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0442 0.4249 0.4249
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0089 0.0089
Echinococcus multilocularis sex peptide receptor 0.0023 0.0089 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0567 0.0567
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.151 0.1504
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0089 0.0082
Brugia malayi Serotonin receptor 0.0023 0.0089 0.0089
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0089 0.0082
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0058 0.0437 0.0437
Onchocerca volvulus 0.0023 0.0089 0.0209
Brugia malayi beta-lactamase family protein 0.0071 0.0567 0.0567
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.1666 0.1661
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0442 0.0329
Onchocerca volvulus 0.0023 0.0089 0.0209
Trichomonas vaginalis heat shock protein, putative 0.002 0.0059 0.0059
Brugia malayi Delta serrate ligand family protein 0.0022 0.0086 0.0086
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0423 0.0417
Loa Loa (eye worm) hypothetical protein 0.002 0.0059 0.0059
Brugia malayi EGF-like domain containing protein 0.0022 0.0086 0.0086
Schistosoma mansoni amine GPCR 0.0023 0.0089 0.0082
Brugia malayi beta-lactamase 0.0071 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.0423
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0431 0.0425
Onchocerca volvulus 0.0029 0.0152 0.0357
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0089 0.0082
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.002 0.002
Loa Loa (eye worm) notch protein 0.0022 0.0086 0.0086
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0007 0.0007
Brugia malayi neuropeptide F receptor 0.0023 0.0089 0.0089
Echinococcus granulosus muscleblind protein 0.0146 0.1309 0.1303
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0296 0.0296
Echinococcus multilocularis muscleblind protein 0.0146 0.1309 0.1303
Brugia malayi Ets-domain containing protein 0.0073 0.0591 0.0591
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0368 0.0368
Onchocerca volvulus 0.0023 0.0089 0.0209
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0151 0.0151
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0442 0.0436
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0181 0.0172
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0601 0.0601
Brugia malayi hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0121 0.1066 0.106
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0448 0.4315 0.431
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.1021 1 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.1359 0.1359
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0089 0.0082
Schistosoma mansoni septate junction protein 0.0022 0.0086 0.0079
Leishmania major heat shock protein 83-1 0.0032 0.0181 0.0181
Echinococcus granulosus heat shock protein 90 0.0025 0.0117 0.011
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0089 0.0082
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0567 0.0549
Loa Loa (eye worm) thymidylate synthase 0.0319 0.3026 0.3026
Brugia malayi hypothetical protein 0.002 0.0059 0.0059
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.002 0.002
Brugia malayi G-protein coupled receptor 0.0023 0.0089 0.0089
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0546 0.0539
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0151 0.0151
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0487 0.048
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0151 0.0131
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0151 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0089 0.0082
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0151 0.1263
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Toxoplasma gondii exonuclease III APE 0.0058 0.0442 0.0433
Mycobacterium ulcerans hypothetical protein 0.0056 0.0423 0.031
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0319 0.3026 0.2944
Echinococcus granulosus orexin receptor type 2 0.0023 0.0089 0.0082
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0089 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.0423
Schistosoma mansoni transcription factor LCR-F1 0.0178 0.1627 0.1622
Brugia malayi hypothetical protein 0.0044 0.0302 0.0302
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0601 0.0601
Echinococcus granulosus microtubule associated protein 2 0.0687 0.6685 0.6682
Trypanosoma cruzi ISWI complex protein 0.0017 0.0034 0.0034
Onchocerca volvulus 0.0023 0.0089 0.0209
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0321 0.3046 0.3046
Schistosoma mansoni neuropeptide receptor 0.0023 0.0089 0.0082
Schistosoma mansoni hypothetical protein 0.0022 0.0086 0.0079
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0151 0.1045
Brugia malayi Ets-domain containing protein 0.0073 0.0591 0.0591
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0151 0.0131
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.0423
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0089 0.0082
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0121 0.1066 0.1048
Mycobacterium tuberculosis Conserved protein 0.0071 0.0567 0.0549
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0229 0.0223
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0886 0.0886
Brugia malayi Cyclic-nucleotide gated cation channel 0.0014 0.0007 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0423 0.0417
Schistosoma mansoni hypothetical protein 0.0512 0.4947 0.4944
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0089 0.0082
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0089 0.0082
Brugia malayi G-protein coupled receptor 0.0023 0.0089 0.0089
Loa Loa (eye worm) Notch2 0.0022 0.0086 0.0086
Toxoplasma gondii thioredoxin reductase 0.0083 0.0692 0.0683
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0089 0.0082
Brugia malayi Dopamine receptor protein 1 0.0023 0.0089 0.0089
Plasmodium vivax glutathione reductase, putative 0.0083 0.0692 0.0673

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.0047 mM Inhibitory activity against Mandelate racemase at pH 7.5 at 25 degree C ChEMBL. 16039120

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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