Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | protein kinase, DNA-activated, catalytic polypeptide | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Echinococcus granulosus | DNA dependent protein kinase catalytic subunit | Get druggable targets OG5_132688 | All targets in OG5_132688 |
Echinococcus multilocularis | DNA dependent protein kinase catalytic subunit | Get druggable targets OG5_132688 | All targets in OG5_132688 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.