Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0991 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0991 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0991 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0991 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0991 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0991 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0991 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0991 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0991 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | Percentage inhibition of [3H]CGS 21680 binding to adenosine A2A receptor in bovine striatal membranes at 20 uM | ChEMBL. | 16335918 |
Inhibition (binding) | = 0 % | Percentage inhibition of [3H]CGS 21680 binding to adenosine A2A receptor in bovine striatal membranes at 20 uM | ChEMBL. | 16335918 |
Inhibition (binding) | = 18 % | Percentage inhibition of [3H]CHA binding to adenosine A1 receptor in bovine cerebral cortical membranes at 20 uM | ChEMBL. | 16335918 |
Inhibition (binding) | = 18 % | Percentage inhibition of [3H]CHA binding to adenosine A1 receptor in bovine cerebral cortical membranes at 20 uM | ChEMBL. | 16335918 |
Inhibition (binding) | = 19 % | Percentage inhibition of [125I]AB-MECA binding to human adenosine A3 receptor expressed in CHO cells at 1 uM | ChEMBL. | 16335918 |
Inhibition (binding) | = 19 % | Percentage inhibition of [125I]AB-MECA binding to human adenosine A3 receptor expressed in CHO cells at 1 uM | ChEMBL. | 16335918 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.