Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutamate receptor NMDA | 0.0128 | 0.6523 | 0.6523 |
Schistosoma mansoni | glutamate receptor kainate | 0.0074 | 0.2219 | 0.2219 |
Loa Loa (eye worm) | integrin beta-2 | 0.0149 | 0.8145 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0115 | 0.5513 | 0.674 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0108 | 0.4944 | 0.4944 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0101 | 0.4346 | 0.4856 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0078 | 0.2559 | 0.2826 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0127 | 0.6428 | 0.6428 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0127 | 0.6428 | 1 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0127 | 0.6428 | 0.7874 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0101 | 0.4346 | 0.4856 |
Echinococcus granulosus | glutamate receptor 2 | 0.0103 | 0.454 | 0.5076 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | WGR domain containing protein | 0.0059 | 0.1099 | 0.1273 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Echinococcus granulosus | glutamate receptor 2 | 0.0136 | 0.7145 | 0.8036 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | LGC-31 protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0047 | 0.0121 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0059 | 0.1099 | 0.133 |
Loa Loa (eye worm) | ACC-1 protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0066 | 0.1632 | 0.1773 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0075 | 0.231 | 0.2543 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0101 | 0.4346 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1099 | 0.1273 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0066 | 0.1632 | 0.1773 |
Schistosoma mansoni | nAChR subunit | 0.0046 | 0.0071 | 0.0071 |
Onchocerca volvulus | 0.0049 | 0.0281 | 0.0491 | |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0127 | 0.6428 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | glutamate receptor kainate | 0.0074 | 0.2219 | 0.2219 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0054 | 0.0686 | 0.0686 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0115 | 0.5513 | 0.6182 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0115 | 0.5513 | 0.674 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0101 | 0.4346 | 0.4856 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0127 | 0.6428 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0054 | 0.0686 | 0.0761 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0101 | 0.4346 | 0.4856 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0101 | 0.4346 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0101 | 0.4346 | 0.4856 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0101 | 0.4346 | 0.4856 |
Chlamydia trachomatis | glutamine binding protein | 0.0047 | 0.0121 | 0.5 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0128 | 0.6523 | 0.7329 |
Loa Loa (eye worm) | ACC-1 protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0075 | 0.231 | 0.2543 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1632 | 0.1934 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0149 | 0.8145 | 1 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0136 | 0.7145 | 0.8036 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0136 | 0.7145 | 0.8036 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0128 | 0.6523 | 0.7329 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0051 | 0.0391 | 0.0363 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.005 | 0.0322 | 0.0285 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0054 | 0.0686 | 0.0686 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0101 | 0.4346 | 0.4346 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0127 | 0.6428 | 0.5 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.0067 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0054 | 0.0686 | 0.0761 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.005 | 0.0322 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0074 | 0.2219 | 0.2219 |
Onchocerca volvulus | 0.0049 | 0.0281 | 0.0491 | |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0059 | 0.1099 | 0.133 |
Echinococcus multilocularis | nAChR subunit | 0.0101 | 0.4346 | 0.4856 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0046 | 0.0071 | 0.0071 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0115 | 0.5513 | 0.674 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0099 | 0.4191 | 0.468 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0127 | 0.6428 | 1 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0059 | 0.1099 | 0.1167 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0101 | 0.4346 | 0.4346 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0127 | 0.6428 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0103 | 0.454 | 0.5076 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Leishmania major | dihydroorotate dehydrogenase | 0.0127 | 0.6428 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0074 | 0.2219 | 0.2661 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Cation transporter family protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | nAChR subunit | 0.0054 | 0.0686 | 0.0698 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0127 | 0.6428 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0101 | 0.4346 | 0.5295 |
Onchocerca volvulus | 0.0054 | 0.0686 | 0.1438 | |
Onchocerca volvulus | 0.0054 | 0.0686 | 0.1438 | |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0054 | 0.0686 | 0.0761 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0158 | 0.8874 | 1 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0047 | 0.0121 | 0.5 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0101 | 0.4346 | 0.4856 |
Onchocerca volvulus | Putative nachr subunit | 0.0101 | 0.4346 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.005 | 0.0322 | 0.0285 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0059 | 0.1099 | 0.1167 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0046 | 0.0071 | 0.0071 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0101 | 0.4346 | 0.4856 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.008 | 0.2726 | 0.3016 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0127 | 0.6428 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0057 | 0.0903 | 0.103 |
Echinococcus granulosus | nAChR subunit | 0.0101 | 0.4346 | 0.4856 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Echinococcus multilocularis | integrin beta 2 | 0.011 | 0.5103 | 0.5716 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0051 | 0.0466 | 0.0466 |
Brugia malayi | WGR domain containing protein | 0.0108 | 0.4944 | 0.6035 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.2906 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0127 | 0.6428 | 0.5 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0099 | 0.4191 | 0.468 |
Brugia malayi | Cation transporter family protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0074 | 0.2219 | 0.2219 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0051 | 0.0391 | 0.0391 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0101 | 0.4346 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0108 | 0.4944 | 1 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0101 | 0.4346 | 0.5295 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0127 | 0.6428 | 1 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.005 | 0.0322 | 0.0311 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0101 | 0.4346 | 0.4856 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.005 | 0.0322 | 0.0285 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0101 | 0.4346 | 0.4346 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0101 | 0.4346 | 0.4856 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0101 | 0.4346 | 0.4346 |
Echinococcus granulosus | integrin beta 2 | 0.011 | 0.5103 | 0.5716 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0094 | 0.3852 | 0.4294 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0101 | 0.4346 | 0.4346 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0046 | 0.0071 | 0.0071 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0046 | 0.0071 | 0.0071 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0101 | 0.4346 | 0.4346 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0059 | 0.1099 | 0.133 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0136 | 0.7145 | 0.8036 |
Loa Loa (eye worm) | glutamate receptor | 0.0057 | 0.0903 | 0.103 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0101 | 0.4346 | 0.4856 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0047 | 0.0121 | 0.5 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0054 | 0.0686 | 0.0686 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.005 | 0.0322 | 0.5 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0108 | 0.4944 | 0.5535 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0051 | 0.0391 | 0.0363 |
Entamoeba histolytica | hypothetical protein | 0.0054 | 0.0686 | 0.0786 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0074 | 0.2219 | 0.2219 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0054 | 0.0686 | 0.0761 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0101 | 0.4346 | 0.5295 |
Echinococcus granulosus | nAChR subunit | 0.0054 | 0.0686 | 0.0698 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0101 | 0.4346 | 0.4856 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Schistosoma mansoni | glutamate receptor kainate | 0.0074 | 0.2219 | 0.2219 |
Brugia malayi | Cation transporter family protein | 0.0101 | 0.4346 | 0.5295 |
Schistosoma mansoni | integrin beta subunit | 0.0088 | 0.332 | 0.332 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0046 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0101 | 0.4346 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0686 | 0.0761 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0158 | 0.8874 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0101 | 0.4346 | 0.4346 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0101 | 0.4346 | 0.5295 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0108 | 0.4944 | 0.5535 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0078 | 0.2559 | 0.2826 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4346 | 0.5295 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0127 | 0.6428 | 0.7874 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0059 | 0.1099 | 0.1099 |
Onchocerca volvulus | 0.0101 | 0.4346 | 1 | |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0054 | 0.0686 | 0.0761 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0127 | 0.6428 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.