Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.1088 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0154 | 0.0049 | 0.0062 |
Schistosoma mansoni | serine/threonine kinase | 0.0212 | 0.066 | 0.066 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0523 | 0.3978 | 0.3978 |
Brugia malayi | Protein kinase domain containing protein | 0.0212 | 0.066 | 0.0847 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0212 | 0.066 | 0.0882 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0265 | 0.0354 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0212 | 0.066 | 1 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0154 | 0.0049 | 0.0062 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0212 | 0.066 | 0.0882 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0523 | 0.3978 | 0.3978 |
Schistosoma mansoni | unc-13 (munc13) | 0.0174 | 0.0265 | 0.0265 |
Entamoeba histolytica | protein kinase, putative | 0.0212 | 0.066 | 1 |
Onchocerca volvulus | 0.0174 | 0.0265 | 0.0627 | |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0212 | 0.066 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0758 | 0.6478 | 0.8659 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0154 | 0.0049 | 0.0065 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0212 | 0.066 | 0.066 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0212 | 0.066 | 0.066 |
Echinococcus granulosus | protein kinase C gamma type | 0.0939 | 0.8407 | 0.8407 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0212 | 0.066 | 0.0882 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0702 | 0.5889 | 0.5889 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0154 | 0.0049 | 0.0065 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Schistosoma mansoni | unc-13 (munc13) | 0.0174 | 0.0265 | 0.0265 |
Brugia malayi | C1-like domain containing protein | 0.0154 | 0.0049 | 0.0062 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0154 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0212 | 0.066 | 0.0882 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0212 | 0.066 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0212 | 0.066 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0349 | 0.212 | 0.212 |
Echinococcus granulosus | NDR protein kinase | 0.0212 | 0.066 | 0.066 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0212 | 0.066 | 0.0882 |
Brugia malayi | Protein kinase domain containing protein | 0.0212 | 0.066 | 0.0847 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0212 | 0.066 | 0.066 |
Toxoplasma gondii | AGC kinase | 0.0212 | 0.066 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0212 | 0.066 | 0.066 |
Brugia malayi | protein kinase C3,putative | 0.0154 | 0.0049 | 0.0062 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0732 | 0.6202 | 0.8289 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.1088 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0174 | 0.0265 | 0.0265 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0165 | 0.0163 | 0.0163 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0523 | 0.3978 | 0.5317 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0212 | 0.066 | 0.0882 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0702 | 0.5889 | 0.5889 |
Onchocerca volvulus | 0.0546 | 0.4225 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.066 | 0.066 |
Brugia malayi | Hr1 repeat family protein | 0.0212 | 0.066 | 0.0847 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0165 | 0.0163 | 0.0163 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0165 | 0.0163 | 0.0163 |
Entamoeba histolytica | protein kinase, putative | 0.0212 | 0.066 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0212 | 0.066 | 0.066 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0702 | 0.5889 | 0.5889 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0212 | 0.066 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0546 | 0.4225 | 0.5647 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0939 | 0.8407 | 0.8407 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0174 | 0.0265 | 0.0265 |
Echinococcus multilocularis | protein kinase c iota type | 0.0361 | 0.2253 | 0.2253 |
Echinococcus granulosus | protein kinase c iota type | 0.0361 | 0.2253 | 0.2253 |
Loa Loa (eye worm) | hypothetical protein | 0.0546 | 0.4225 | 0.5647 |
Schistosoma mansoni | protein kinase C mu | 0.0154 | 0.0049 | 0.0049 |
Schistosoma mansoni | protein kinase C | 0.0174 | 0.0265 | 0.0265 |
Trichomonas vaginalis | AGC family protein kinase | 0.0212 | 0.066 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0154 | 0.0049 | 0.0049 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0212 | 0.066 | 0.066 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0212 | 0.066 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0546 | 0.4225 | 0.5647 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0212 | 0.066 | 0.0847 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1088 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0696 | 0.5818 | 0.7776 |
Brugia malayi | Protein kinase c protein 2 | 0.0881 | 0.7795 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0154 | 0.0049 | 0.0049 |
Brugia malayi | Protein kinase domain containing protein | 0.0212 | 0.066 | 0.0847 |
Echinococcus granulosus | unc 13 munc13 | 0.0174 | 0.0265 | 0.0265 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0154 | 0.0049 | 0.0049 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.066 | 0.066 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.066 | 0.066 |
Brugia malayi | protein kinase C II. | 0.0523 | 0.3978 | 0.5103 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.066 | 0.066 |
Schistosoma mansoni | atypical protein kinase C | 0.0361 | 0.2253 | 0.2253 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0174 | 0.0265 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0852 | 0.7482 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0523 | 0.3978 | 0.3978 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.5889 | 0.7871 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0212 | 0.066 | 0.0882 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 | Antagonist activity against protein Kinase C | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.