Detailed information for compound 348708

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 686.751 | Formula: C36H40F2N8O4
  • H donors: 1 H acceptors: 4 LogP: 4.5 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: C[C@@H]([C@H](n1ncn(c1=O)c1ccc(cc1)N1CCN(CC1)c1ccc(cc1)OC[C@@H]1CO[C@@](C1)(Cn1cncn1)c1ccc(cc1F)F)C)O
  • InChi: 1S/C36H40F2N8O4/c1-25(26(2)47)46-35(48)45(24-41-46)31-6-4-29(5-7-31)42-13-15-43(16-14-42)30-8-10-32(11-9-30)49-19-27-18-36(50-20-27,21-44-23-39-22-40-44)33-12-3-28(37)17-34(33)38/h3-12,17,22-27,47H,13-16,18-21H2,1-2H3/t25-,26+,27-,36+/m1/s1
  • InChiKey: DWAARNRPFQTVRT-YEHIXWHBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable peptidase 0.0067 0.0111 0.011
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0114 0.0223 0.0212
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0189 0.0401 0.09
Onchocerca volvulus 0.0061 0.0098 0.0259
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0114 0.0223 0.0222
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable two component sensor kinase 0.0114 0.0223 0.0222
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0022 0.002
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0811 0.1881 0.4213
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0029 0.0064
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.0307 0.0689
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Trichomonas vaginalis receptor histidine kinase, putative 0.0114 0.0223 0.0478
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Giardia lamblia Alanyl dipeptidyl peptidase 0.0028 0.0019 0.002
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0074 0.0127 0.0286
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0052 0.0117
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Schistosoma mansoni cpg binding protein 0.0122 0.0242 0.0544
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0241 0.0541
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0023 0.0053
Toxoplasma gondii hypothetical protein 0.005 0.0071 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Trypanosoma brucei DNA topoisomerase IA, putative 0.0212 0.0456 0.0729
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0811 0.1881 0.4213
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.006 0.0095 0.0212
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0074 0.0127 0.0192
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0098 0.0219
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0056
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0025 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0023 0.0052
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Onchocerca volvulus 0.0024 0.001 0.0026
Echinococcus multilocularis Squalene phytoene synthase 0.0189 0.0401 0.09
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0145 0.0297 0.0666
Echinococcus multilocularis 0.0043 0.0055 0.0123
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0044 0.0055
Brugia malayi MH2 domain containing protein 0.0121 0.0241 0.0541
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0055 0.0055
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0056 0.0124
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0103 0.0196 0.0441
Chlamydia trachomatis endonuclease IV 0.0077 0.0135 0.0111
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0024 0.001 0.0023
Schistosoma mansoni DNA topoisomerase II 0.1892 0.4451 1
Leishmania major tagatose-6-phosphate kinase-like protein 0.0162 0.0338 0.0537
Leishmania major squalene synthase, putative 0.0605 0.1392 0.2262
Trypanosoma brucei hypothetical protein, conserved 0.021 0.0453 0.0724
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0031 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0024 0.001 0.0023
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0023 0.0052
Toxoplasma gondii hypothetical protein 0.0601 0.1381 0.1372
Trypanosoma cruzi adenosine kinase, putative 0.1424 0.3338 0.545
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0098 0.0219
Schistosoma mansoni aldehyde dehydrogenase 0.0256 0.056 0.1259
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0063 0.0053
Mycobacterium ulcerans carveol-like dehydrogenase 0.0024 0.001 0.001
Wolbachia endosymbiont of Brugia malayi recombinase A 0.011 0.0213 0.0203
Brugia malayi DNA topoisomerase III 0.0212 0.0456 0.1023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.0102
Echinococcus granulosus flap endonuclease 1 0.0026 0.0015 0.0033
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Onchocerca volvulus 0.0036 0.0037 0.0098
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.018 0.038 0.0853
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Entamoeba histolytica ribokinase, putative 0.0162 0.0338 0.0738
Trichomonas vaginalis adenosine deaminase, putative 0.009 0.0167 0.0353
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Echinococcus granulosus cpg binding protein 0.0122 0.0242 0.0543
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0114 0.0223 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0056 0.0075
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0329 0.0738
Giardia lamblia Rab geranylgeranyltransferase 0.0811 0.1881 0.4486
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0055 0.0055
Schistosoma mansoni endoplasmin 0.0114 0.0223 0.05
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi Serotonin receptor 0.0061 0.0098 0.0219
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0271 0.061
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Echinococcus granulosus heat shock protein 0.0114 0.0223 0.0499
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0098 0.0219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0023 0.0052
Schistosoma mansoni acetylcholine receptor subunit beta 0.0028 0.0018 0.0041
Brugia malayi Ets-domain containing protein 0.0074 0.0128 0.0286
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0044 0.0098
Toxoplasma gondii hypothetical protein 0.0028 0.0019 0.0008
Loa Loa (eye worm) GABA receptor subunit 0.0032 0.0029 0.0065
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0201 0.043 0.043
Loa Loa (eye worm) jmjC domain-containing protein 0.0108 0.0209 0.0469
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0031 0.0034
Trypanosoma brucei ribokinase, putative 0.0162 0.0338 0.0537
Schistosoma mansoni jumonji/arid domain-containing protein 0.0411 0.093 0.2089
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0028 0.0018 0.004
Schistosoma mansoni adenosine kinase 0.1424 0.3338 0.7499
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0114 0.0223 0.0222
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0098 0.0219
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0067 0.0111 0.011
Loa Loa (eye worm) twinkle helicase 0.0112 0.0219 0.0492
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0201 0.043 0.043
Entamoeba histolytica adenosine deaminase, putative 0.009 0.0167 0.0353
Brugia malayi Muscleblind-like protein 0.0305 0.0678 0.1522
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0146 0.03 0.0674
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0114 0.0223 0.0478
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0114 0.0223 0.0222
Schistosoma mansoni myosin xvIII 0.0061 0.0098 0.022
Loa Loa (eye worm) hypothetical protein 0.1093 0.2552 0.5732
Plasmodium vivax adenosine/AMP deaminase, putative 0.0029 0.0022 0.0012
Toxoplasma gondii hypothetical protein 0.021 0.0453 0.0443
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0114 0.0223 0.0347
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0108 0.0209 0.0199
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Trypanosoma brucei developmentally regulated phosphoprotein 0.0114 0.0223 0.0347
Echinococcus multilocularis serotonin receptor 0.0061 0.0098 0.0219
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.021 0.0453 0.1016
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0055 0.0055
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Echinococcus multilocularis expressed protein 0.038 0.0855 0.192
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Loa Loa (eye worm) TOPoisomerase family member 0.1892 0.4451 1
Giardia lamblia DNA topoisomerase II 0.1779 0.4181 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0209 0.0469
Echinococcus multilocularis glycine receptor subunit beta 0.006 0.0095 0.0212
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0055 0.0055
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.0095 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Brugia malayi Adenosine kinase-like 0.1424 0.3338 0.7499
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0212 0.0456 0.1003
Loa Loa (eye worm) heat shock protein 90 0.0114 0.0223 0.0499
Toxoplasma gondii histone lysine methyltransferase SET1 0.0226 0.0489 0.0479
Echinococcus granulosus glycine receptor subunit beta 0.006 0.0095 0.0212
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Plasmodium vivax DNA topoisomerase II, putative 0.1892 0.4451 0.4445
Schistosoma mansoni nAChR subunit 0.0028 0.0018 0.0041
Brugia malayi hypothetical protein 0.0162 0.0337 0.0756
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.001 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.056 0.056
Plasmodium falciparum glutathione reductase 0.0031 0.0025 0.0022
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0074 0.0127 0.0192
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Mycobacterium tuberculosis Possible two component sensor kinase 0.0114 0.0223 0.0222
Giardia lamblia DNA topoisomerase III 0.0212 0.0456 0.1068
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0024 0.001 0.0024
Plasmodium falciparum thioredoxin reductase 0.0088 0.0162 0.0159
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0023 0.0052
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0098 0.0219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) RNA binding protein 0.0134 0.0271 0.0609
Schistosoma mansoni jumonji domain containing protein 0.0108 0.0209 0.0469
Leishmania major adenosine kinase, putative 0.1424 0.3338 0.545
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0271 0.061
Loa Loa (eye worm) jmjC domain-containing protein 0.0108 0.0209 0.0469
Leishmania major developmentally regulated phosphoprotein-like protein 0.0114 0.0223 0.0347
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0028 0.0019 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0055 0.0055
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0023 0.0052
Brugia malayi larval opioid receptor 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Echinococcus granulosus g protein coupled receptor 0.0061 0.0098 0.0219
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0118 0.0233 0.0522
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0051 0.0115
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0098 0.0219
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.018 0.017
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.1892 0.4451 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.034 0.034
Echinococcus multilocularis expressed conserved protein 0.0095 0.0178 0.0399
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0032 0.0029 0.0066
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Onchocerca volvulus 0.0061 0.0098 0.0259
Echinococcus granulosus lysine specific demethylase 5A 0.0411 0.093 0.2088
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0811 0.1881 0.4213
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0811 0.1881 0.4227
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0023 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.018 0.0406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0023 0.0052
Plasmodium falciparum basic transcription factor 3b, putative 0.0111 0.0216 0.0212
Brugia malayi prolyl oligopeptidase family protein 0.0028 0.0019 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0098 0.0219
Brugia malayi hypothetical protein 0.0026 0.0013 0.0029
Brugia malayi G-protein coupled receptor 0.0061 0.0098 0.0219
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0031 0.0025 0.0015
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0223 0.0484 0.0483
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0051 0.0115
Onchocerca volvulus Neuropeptide F receptor homolog 0.0061 0.0098 0.0259
Chlamydia trachomatis DNA gyrase subunit B 0.2537 0.5985 0.5975
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.006 0.0095 0.0212
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.0068 0.0152
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus multilocularis peptidase Clp (S14 family) 0.0101 0.0193 0.0433
Onchocerca volvulus 0.0024 0.001 0.0026
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.0102
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0031 0.0025 0.0056
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.018 0.038 0.0853
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0136 0.0277 0.0276
Loa Loa (eye worm) hypothetical protein 0.0061 0.0097 0.0218
Mycobacterium leprae Probable two-component sensor kinase 0.0114 0.0223 0.0552
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0038
Leishmania major DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Echinococcus granulosus oxidoreductase 0.0024 0.001 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Echinococcus granulosus thioredoxin glutathione reductase 0.0089 0.0163 0.0366
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0098 0.0219
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0061 0.0098 0.022
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0098 0.0219
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0015 0.0011
Echinococcus multilocularis jumonji domain containing 1A 0.0108 0.0209 0.0469
Brugia malayi G protein-coupled receptor 0.0061 0.0098 0.0219
Trypanosoma cruzi polo-like protein kinase, putative 0.0193 0.0411 0.0656
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0013 0.0005
Leishmania major basic transcription factor 3a, putative 0.0111 0.0216 0.0336
Toxoplasma gondii hypothetical protein 0.0053 0.0079 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0044 0.0075
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0031 0.0034
Schistosoma mansoni adenosine deaminase-related 0.009 0.0167 0.0376
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0013 0.0003
Schistosoma mansoni pyruvate dehydrogenase 0.0114 0.0223 0.05
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Onchocerca volvulus 0.006 0.0095 0.0251
Trichomonas vaginalis glutathione reductase, putative 0.0031 0.0025 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0092 0.0206
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0031 0.0034
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0098 0.022
Brugia malayi jmjC domain containing protein 0.0108 0.0209 0.0469
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.006 0.0095 0.0212
Schistosoma mansoni acetylcholine receptor-related 0.0028 0.0018 0.0041
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0114 0.0223 0.0222
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0024 0.001 0.0023
Echinococcus granulosus carbonyl reductase 1 0.0024 0.001 0.0023
Schistosoma mansoni neuropeptide receptor 0.0061 0.0098 0.022
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0055 0.0055
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0055 0.0055
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0114 0.0223 0.0222
Brugia malayi Cytochrome P450 family protein 0.0122 0.0241 0.0542
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0296 0.0664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Toxoplasma gondii exonuclease III APE 0.0042 0.0051 0.0041
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0201 0.043 0.043
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus granulosus ribokinase 0.0162 0.0338 0.0759
Loa Loa (eye worm) TAR-binding protein 0.0134 0.0271 0.0609
Mycobacterium ulcerans putative regultory protein 0.0114 0.0223 0.0222
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0098 0.0219
Brugia malayi hypothetical protein 0.0028 0.0018 0.004
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0193 0.0432
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.021 0.0453 0.0724
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.1644 0.3861 0.3855
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.018 0.038 0.0853
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0201 0.043 0.1068
Trypanosoma cruzi oligopeptidase b 0.0067 0.0111 0.0164
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trypanosoma cruzi DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Schistosoma mansoni opsin-like receptor 0.0061 0.0098 0.022
Leishmania major hypothetical protein, conserved 0.0189 0.0401 0.064
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.001 0.0026
Mycobacterium tuberculosis Conserved protein 0.0038 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Trypanosoma cruzi phytoene synthase, putative 0.0189 0.0401 0.064
Loa Loa (eye worm) hypothetical protein 0.0058 0.0089 0.02
Onchocerca volvulus 0.0061 0.0098 0.0259
Loa Loa (eye worm) hypothetical protein 0.0305 0.0678 0.1522
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0098 0.0219
Entamoeba histolytica heat shock protein 90, putative 0.0114 0.0223 0.0478
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0063 0.0119
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0136 0.0277 0.0621
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0098 0.022
Loa Loa (eye worm) endoplasmin 0.0114 0.0223 0.0499
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.006 0.0095 0.0212
Mycobacterium tuberculosis Conserved protein 0.0038 0.0044 0.0043
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.01 0.0225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0052 0.0117
Mycobacterium ulcerans glutaminase 0.0269 0.0592 0.0591
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0023 0.0052
Brugia malayi Death domain containing protein 0.0118 0.0233 0.0522
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0023 0.0052
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Onchocerca volvulus 0.0061 0.0098 0.0259
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0098 0.022
Brugia malayi jmjC domain containing protein 0.0467 0.1062 0.2385
Onchocerca volvulus Sepiapterin reductase homolog 0.0024 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Loa Loa (eye worm) fli-1 protein 0.0224 0.0484 0.1087
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.056 0.056
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0028 0.0018 0.004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0023 0.0052
Plasmodium vivax basic transcription factor 3b, putative 0.0111 0.0216 0.0206
Schistosoma mansoni adenosine kinase 0.1424 0.3338 0.7499
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Giardia lamblia Heat shock protein HSP 90-alpha 0.0114 0.0223 0.0509
Echinococcus multilocularis phd:f box containing protein 0.0108 0.0209 0.0469
Giardia lamblia Pms1-like protein 0.0114 0.0223 0.0509
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0023 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0023 0.0052
Onchocerca volvulus 0.0032 0.0029 0.0076
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0013 0.0003
Plasmodium vivax DNA gyrase subunit A, putative 0.4226 1 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0136
Onchocerca volvulus 0.0028 0.0018 0.0047
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0067 0.0151
Echinococcus granulosus lysine specific demethylase 6a 0.0108 0.0209 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0051 0.0048
Brugia malayi Flap endonuclease-1 0.0026 0.0015 0.0033
Mycobacterium ulcerans lipase LipD 0.0038 0.0044 0.0043
Onchocerca volvulus 0.0061 0.0098 0.0259
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.009 0.0167 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.017 0.0383
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0037 0.0083
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0114 0.0223 0.0222
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Trypanosoma cruzi Vacuolar proton pyrophosphatase 1, putative 0.0405 0.0916 0.1483
Entamoeba histolytica adenosine deaminase, putative 0.009 0.0167 0.0353
Onchocerca volvulus 0.0115 0.0227 0.0602
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0023 0.0053
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0467 0.1062 0.2385
Brugia malayi beta-NAC-like protein 0.0111 0.0216 0.0484
Plasmodium vivax thioredoxin reductase, putative 0.0088 0.0162 0.0152
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0023 0.0053
Mycobacterium ulcerans phytoene synthase, CrtB 0.0189 0.0401 0.04
Onchocerca volvulus 0.0061 0.0098 0.0259
Onchocerca volvulus Netrin receptor homolog 0.0118 0.0233 0.0618
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi dehydrogenases, short chain protein 2 0.0024 0.001 0.0023
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0051 0.0051
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0193 0.0432
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0061 0.0098 0.022
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.021 0.0453 0.0996
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.021 0.0453 0.1016
Echinococcus granulosus phd:f box containing protein 0.0108 0.0209 0.0469
Brugia malayi neuropeptide F receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis sex peptide receptor 0.0061 0.0098 0.0219
Brugia malayi ecdysteroid receptor 0.003 0.0023 0.0052
Onchocerca volvulus 0.0061 0.0098 0.0259
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0098 0.022
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.006 0.0095 0.0212
Brugia malayi G-protein coupled receptor 0.0061 0.0098 0.0219
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.018 0.038 0.0853
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.006 0.0095 0.0212
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0118 0.0233 0.0522
Trypanosoma cruzi DNA topoisomerase II, putative 0.1681 0.3948 0.6449
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.006 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0025 0.0024
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0023 0.0053
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0162 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0023 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0411 0.0924
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.001 0.001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0245 0.0536 0.0535
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.001 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0023 0.0052
Echinococcus granulosus allatostatin A receptor 0.0061 0.0098 0.0219
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0015 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0055 0.0055
Entamoeba histolytica prolyl oligopeptidase family protein 0.0028 0.0019 0.0019
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0024 0.001 0.001
Echinococcus granulosus adenosine deaminase 0.009 0.0167 0.0375
Trypanosoma cruzi oligopeptidase b 0.0067 0.0111 0.0164
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Trypanosoma cruzi prolyl endopeptidase 0.0146 0.03 0.0474
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0098 0.0219
Leishmania major hypothetical protein, conserved 0.0108 0.0209 0.0325
Mycobacterium ulcerans recombinase A 0.011 0.0213 0.0213
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0031 0.0046
Loa Loa (eye worm) glutaminase 2 0.0269 0.0592 0.1329
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0098 0.0219
Onchocerca volvulus 0.0024 0.001 0.0026
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0024 0.001 0.001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.001 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0023 0.0052
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0024 0.001 0.0024
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.009 0.0167 0.0414
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0114 0.0223 0.0222
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0063 0.0141
Onchocerca volvulus 0.0024 0.001 0.0026
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0098 0.022
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0098 0.0219
Leishmania major adenine aminohydrolase 0.009 0.0167 0.0257
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0024 0.0054
Toxoplasma gondii DNA topoisomerase 2, putative 0.1892 0.4451 0.4445
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0088 0.0162 0.0161
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0024 0.001 0.0023
Trypanosoma cruzi heat shock protein 90, putative 0.0114 0.0223 0.0347
Brugia malayi hypoxia-induced factor 1 0.0149 0.0307 0.0689
Schistosoma mansoni carbonyl reductase 0.0024 0.001 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0154 0.032 0.0309
Echinococcus multilocularis muscleblind protein 0.0305 0.0678 0.1522
Echinococcus multilocularis somatostatin receptor 0.0061 0.0098 0.0219
Plasmodium falciparum DNA gyrase subunit B 0.2537 0.5985 0.5983
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0051 0.0092
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0032 0.0029 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.017 0.0382
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0301 0.0476
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0029 0.0065
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0098 0.0219
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.4226 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0114 0.0223 0.0222
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus peregrin 0.0034 0.0033 0.0074
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Mycobacterium tuberculosis Probable oxidoreductase 0.0223 0.0484 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0118 0.0233 0.0522
Echinococcus multilocularis neuropeptide receptor A26 0.0563 0.1292 0.2902
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0051 0.0041
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0023 0.0052
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0056 0.0124
Echinococcus multilocularis dnaJ subfamily B 0.1641 0.3855 0.866
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0051 0.0067
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0067 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0029
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0135 0.0125
Trypanosoma cruzi DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Echinococcus granulosus fmrfamide receptor 0.0061 0.0098 0.0219
Brugia malayi prolyl oligopeptidase family protein 0.0146 0.03 0.0673
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0223 0.0484 0.12
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0019 0.0008
Entamoeba histolytica hypothetical protein 0.0032 0.0029 0.0042
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0114 0.0223 0.0499
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0024 0.001 0.001
Onchocerca volvulus 0.006 0.0095 0.0251
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0162 0.0338 0.0759
Toxoplasma gondii DNA topoisomerase family protein 0.0212 0.0456 0.0446
Brugia malayi serine/threonine-protein kinase plk-2 0.0193 0.0411 0.0923
Onchocerca volvulus Adenosine deaminase homolog 0.009 0.0167 0.0444
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0056 0.0125
Plasmodium vivax JmjC domain containing protein 0.0108 0.0209 0.0199
Chlamydia trachomatis recombinase RecA 0.011 0.0213 0.0189
Giardia lamblia PHD finger protein 15 0.003 0.0024 0.0033
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0256 0.056 0.1258
Echinococcus granulosus g protein coupled receptor 0.0061 0.0098 0.0219
Plasmodium falciparum DNA topoisomerase 2 0.1892 0.4451 0.4449
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.006 0.0095 0.0212
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0013 0.0005
Echinococcus multilocularis geminin 0.053 0.1212 0.2722
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0098 0.0219
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0212 0.0456 0.1023
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0098 0.0219
Mycobacterium ulcerans oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0122 0.0241 0.0542
Schistosoma mansoni phosphatidylserine receptor 0.0108 0.0209 0.0469
Brugia malayi PHD-finger family protein 0.003 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium ulcerans short-chain type oxidoreductase 0.0024 0.001 0.001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0025 0.0015
Echinococcus multilocularis lysine specific demethylase 5A 0.0404 0.0914 0.2053
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0056 0.0125
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0024 0.001 0.0023
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0201 0.043 0.043
Trichomonas vaginalis heat shock protein, putative 0.0114 0.0223 0.0478
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0098 0.022
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 2, putative 0.0405 0.0916 0.1483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0128 0.0286
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0098 0.022
Loa Loa (eye worm) ACC-1 protein 0.006 0.0095 0.0212
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0015 0.0011
Loa Loa (eye worm) AMP deaminase 0.0029 0.0022 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.0453 0.0724
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0114 0.0223 0.0222
Toxoplasma gondii ABC1 family protein 0.0038 0.0044 0.0033
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0098 0.0219
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0023 0.0061
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0193 0.0411 0.0656
Brugia malayi hypothetical protein 0.0043 0.0056 0.0125
Brugia malayi Ets-domain containing protein 0.0074 0.0128 0.0286
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0811 0.1881 0.4226
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0028 0.0018 0.004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0024 0.0054
Onchocerca volvulus 0.0061 0.0098 0.0259
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Onchocerca volvulus 0.0028 0.0018 0.0047
Echinococcus granulosus carbonyl reductase 1 0.0024 0.001 0.0023
Loa Loa (eye worm) acetyltransferase 0.0158 0.0329 0.0738
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0146 0.03 0.0673
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0056 0.0124
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0092 0.0206
Mycobacterium tuberculosis Probable reductase 0.0201 0.043 0.043
Onchocerca volvulus Huntingtin homolog 0.0134 0.027 0.0719
Giardia lamblia Kinase, PLK 0.0193 0.0411 0.0961
Brugia malayi dehydrogenases, short chain protein 9 0.0024 0.001 0.0023
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0054 0.005
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0114 0.0223 0.0552
Loa Loa (eye worm) hypothetical protein 0.0915 0.2128 0.4781
Onchocerca volvulus 0.0059 0.0092 0.0243
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0162 0.0338 0.0338
Echinococcus granulosus geminin 0.053 0.1212 0.2722
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.0095 0.0213
Brugia malayi jmjC domain containing protein 0.0411 0.093 0.2088
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0023 0.0053
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0108 0.0209 0.0469
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0056 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0216 0.0462
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.001 0.0023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0015 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.017 0.0383
Schistosoma mansoni Replicative DNA helicase 0.0393 0.0887 0.1992
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0114 0.0223 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.002 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0037 0.0037
Onchocerca volvulus 0.0743 0.172 0.4582
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0024 0.001 0.0023
Leishmania major DNA topoisomerase 1A 0.0212 0.0456 0.0729
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0193 0.0411 0.0923
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.2593 0.6116 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0295
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0055 0.0055
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.006 0.0095 0.0212
Plasmodium vivax hypothetical protein, conserved 0.003 0.0024 0.0014
Brugia malayi excitatory GABA receptor EXP-1A 0.006 0.0095 0.0212
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Loa Loa (eye worm) DNA topoisomerase III 0.0212 0.0456 0.1023
Giardia lamblia Ribokinase 0.0162 0.0338 0.0786
Schistosoma mansoni hypothetical protein 0.003 0.0024 0.0054
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0024 0.001 0.001
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0248 0.0542 0.1217
Brugia malayi Adenosine/AMP deaminase family protein 0.009 0.0167 0.0375
Loa Loa (eye worm) hypothetical protein 0.0732 0.1693 0.3803
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0128 0.0286
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Schistosoma mansoni hypothetical protein 0.0043 0.0055 0.0124
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0029 0.0022 0.002
Onchocerca volvulus 0.0061 0.0098 0.0259
Brugia malayi hypothetical protein 0.0028 0.0018 0.004
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0006 0.0012
Onchocerca volvulus 0.0096 0.018 0.0479
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0189 0.0401 0.1067
Schistosoma mansoni amine GPCR 0.0061 0.0098 0.022
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.011 0.0213 0.0529
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0031 0.0025 0.0024
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0166 0.0373
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Trypanosoma cruzi heat shock protein 90, putative 0.0114 0.0223 0.0347
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0056 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0044 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0023 0.0052
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0108 0.0209 0.0199
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.001 0.0007
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0023 0.0052
Trypanosoma cruzi adenosine kinase, putative 0.1424 0.3338 0.545
Schistosoma mansoni nAChR subunit 0.0028 0.0018 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0411 0.093 0.2088
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.001 0.0023
Trypanosoma brucei cytochrome P450, putative 0.0054 0.008 0.0114
Loa Loa (eye worm) hypothetical protein 0.009 0.0167 0.0375
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0023 0.0052
Toxoplasma gondii kinase, pfkB family protein 0.0162 0.0338 0.0328
Loa Loa (eye worm) hypothetical protein 0.0162 0.0338 0.0759
Schistosoma mansoni hypothetical protein 0.0103 0.0199 0.0446
Echinococcus multilocularis adenosine deaminase 0.009 0.0167 0.0375
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0056 0.0124
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.021 0.0453 0.1016
Loa Loa (eye worm) hypothetical protein 0.0108 0.0209 0.0469
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Schistosoma mansoni opsin-like receptor 0.0061 0.0098 0.022
Brugia malayi beta-lactamase family protein 0.0038 0.0044 0.0098
Trypanosoma brucei prolyl oligopeptidase, putative 0.0067 0.0111 0.0164
Schistosoma mansoni tumor necrosis factor receptor related 0.018 0.038 0.0853
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Onchocerca volvulus 0.0024 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0136 0.0277 0.0276
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0061 0.0098 0.0259
Schistosoma mansoni netrin receptor unc5 0.0118 0.0233 0.0522
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0074 0.0127 0.0192
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable dehydrogenase 0.0201 0.043 0.043
Brugia malayi RNA recognition motif domain containing protein 0.0134 0.0271 0.0609
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0126 0.0252 0.0228
Trypanosoma brucei heat shock protein 90, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Schistosoma mansoni ap endonuclease 0.0042 0.0051 0.0115
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0114 0.0223 0.0212
Schistosoma mansoni hypothetical protein 0.0189 0.0401 0.0901
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0055 0.0055
Echinococcus granulosus hypothetical protein 0.0024 0.001 0.0023
Echinococcus granulosus Squalene phytoene synthase 0.0189 0.0401 0.09
Leishmania major ribokinase, putative 0.0162 0.0338 0.0537
Brugia malayi ORL1-like opioid receptor 0.0061 0.0098 0.0219
Echinococcus granulosus expressed protein 0.0034 0.0033 0.0073
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0212 0.0456 0.1003
Onchocerca volvulus 0.0162 0.0338 0.09
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi putative neuropeptide receptor 0.0061 0.0098 0.0219
Trypanosoma brucei trypanothione reductase 0.0088 0.0162 0.0248
Echinococcus granulosus g protein coupled receptor 0.0061 0.0098 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0028 0.0019 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Echinococcus multilocularis adenosine kinase 0.1424 0.3338 0.7499
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0689 0.1111
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.001 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0295
Toxoplasma gondii heat shock protein HSP90 0.0114 0.0223 0.0212
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0055 0.0055
Loa Loa (eye worm) RecQ helicase 0.0024 0.0011 0.0023
Mycobacterium leprae Probable lipase LipE 0.0038 0.0044 0.0107
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0212 0.0456 0.1024
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.018 0.0406
Trypanosoma cruzi heat shock protein 85, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) prolyl oligopeptidase 0.0191 0.0408 0.0915
Entamoeba histolytica DNA topoisomerase III, putative 0.0212 0.0456 0.1003
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.006 0.0095 0.0212
Schistosoma mansoni heat shock protein 0.0114 0.0223 0.05
Echinococcus multilocularis glycine receptor subunit beta 0.006 0.0095 0.0212
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0055 0.0055
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0098 0.0219
Echinococcus multilocularis retinol dehydrogenase 13 0.0024 0.001 0.0023
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0101 0.0193 0.0478
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0044 0.0043
Trypanosoma cruzi adenosine kinase, putative 0.0162 0.0338 0.0537
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0028 0.0019 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0055 0.0055
Trypanosoma cruzi heat shock protein 85, putative 0.0114 0.0223 0.0347
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.0024
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0055 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.017 0.0383
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0013 0.0005
Echinococcus granulosus heat shock protein 90 0.0114 0.0223 0.0499
Schistosoma mansoni amine GPCR 0.0061 0.0098 0.022
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0044 0.0098
Trypanosoma brucei heat shock protein 90, putative 0.0114 0.0223 0.0347
Trypanosoma cruzi adenosine kinase, putative 0.0162 0.0338 0.0537
Onchocerca volvulus 0.0024 0.001 0.0026
Loa Loa (eye worm) CYP4Cod1 0.0054 0.008 0.018
Brugia malayi Ribokinase 0.0162 0.0338 0.0759
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0223 0.0484 0.0483
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi Cytochrome P450 family protein 0.0054 0.008 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Echinococcus multilocularis nAChR subunit 0.006 0.0095 0.0212
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.001 0.001
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0393 0.0887 0.2202
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0044 0.0075
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0135 0.0303
Treponema pallidum adenosine deaminase 0.009 0.0167 0.0142
Echinococcus multilocularis JmjC domain containing protein 4 0.0108 0.0209 0.0469
Onchocerca volvulus 0.006 0.0095 0.0251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Brugia malayi Thioredoxin reductase 0.0088 0.0162 0.0363
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.006 0.0095 0.0212
Echinococcus granulosus bloom syndrome protein 0.0024 0.0011 0.0023
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0056 0.0075
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0191 0.0408 0.0915
Entamoeba histolytica DNA topoisomerase II, putative 0.1892 0.4451 1
Trypanosoma brucei DNA topoisomerase ii 0.2593 0.6116 1
Schistosoma mansoni lamin 0.0059 0.0092 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0033 0.005
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0024 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0043 0.0056 0.0125
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0022 0.002
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0114 0.0223 0.0222
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0023 0.0053
Echinococcus granulosus transcription factor btf3 0.0111 0.0216 0.0484
Trypanosoma cruzi heat shock protein 85, putative 0.0114 0.0223 0.0347
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.001 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0023 0.0052
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0044 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0098 0.0219
Trypanosoma cruzi ribokinase, putative 0.0162 0.0338 0.0537
Echinococcus granulosus tar DNA binding protein 0.0134 0.0271 0.0609
Plasmodium vivax DNA topoisomerase 3, putative 0.0212 0.0456 0.0446
Plasmodium falciparum glutathione reductase 0.0088 0.0162 0.0159
Echinococcus granulosus JmjC domain containing protein 4 0.0108 0.0209 0.0469
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0271 0.061
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0054 0.0104
Echinococcus multilocularis peregrin 0.0034 0.0033 0.0074
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0098 0.0219
Plasmodium falciparum V-type H(+)-translocating pyrophosphatase, putative 0.0405 0.0916 0.0912
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0023 0.0053
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0098 0.022
Brugia malayi Serotonin receptor 0.0061 0.0098 0.0219
Schistosoma mansoni ribokinase 0.0162 0.0338 0.076
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Onchocerca volvulus 0.0061 0.0098 0.0259
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0114 0.0223 0.0222
Echinococcus multilocularis oxidoreductase 0.0024 0.001 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0271 0.061
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Brugia malayi glutaminase DH11.1 0.0269 0.0592 0.1329
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0098 0.0219
Echinococcus granulosus jumonji domain containing 1A 0.0108 0.0209 0.0469
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0054 0.008 0.008
Toxoplasma gondii kinase, pfkB family protein 0.1424 0.3338 0.3331
Brugia malayi hypothetical protein 0.0046 0.0061 0.0136
Schistosoma mansoni intermediate filament proteins 0.0059 0.0092 0.0207
Mycobacterium tuberculosis Conserved protein 0.0114 0.0223 0.0222
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0013 0.001
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.0689 0.1111
Mycobacterium ulcerans two component regulator - sensor kinase 0.0114 0.0223 0.0222
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0114 0.0223 0.0222
Schistosoma mansoni hypothetical protein 0.053 0.1212 0.2722
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0757 0.1753 0.2854
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Brugia malayi nuclear hormone receptor 0.003 0.0023 0.0052
Mycobacterium leprae putative cytochrome p450 0.0043 0.0055 0.0135
Echinococcus granulosus hypothetical protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0023 0.0061
Brugia malayi hypothetical protein 0.0024 0.001 0.0023
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0027 0.006
Onchocerca volvulus 0.0024 0.001 0.0026
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0811 0.1881 0.4226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Trypanosoma brucei adenosine kinase, putative 0.1424 0.3338 0.545
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0811 0.1881 0.1878
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0029 0.0065
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0023 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0296 0.0664
Schistosoma mansoni neuropeptide receptor 0.0061 0.0098 0.022
Mycobacterium tuberculosis Adenosine kinase 0.0162 0.0338 0.0338
Trypanosoma brucei oligopeptidase b 0.0067 0.0111 0.0164
Loa Loa (eye worm) hypothetical protein 0.0077 0.0135 0.0303
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Trichomonas vaginalis glutaminase, putative 0.0269 0.0592 0.131
Echinococcus granulosus neuropeptide receptor 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0055 0.0055
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0162 0.0248
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.006 0.0095 0.0213
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0031 0.0025 0.0024
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0312 0.0695 0.156
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0193 0.041
Leishmania major cytochrome p450-like protein 0.0043 0.0055 0.0073
Loa Loa (eye worm) jmjC domain-containing protein 0.0108 0.0209 0.0469
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.017 0.0382
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0028 0.0019 0.0019
Brugia malayi Endoplasmin precursor 0.0114 0.0223 0.0499
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0114 0.0225 0.0504
Plasmodium falciparum peptidase, putative 0.0028 0.0019 0.0015
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0079 0.0054
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0467 0.1062 0.2385
Onchocerca volvulus AMP deaminase 2 homolog 0.0029 0.0022 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.1093 0.2552 0.5732
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.0095 0.0213
Echinococcus multilocularis heat shock protein 0.0114 0.0223 0.0499
Leishmania major hypothetical protein, conserved 0.0038 0.0044 0.0055
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0154 0.032 0.0309
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.001 0.001
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.1599 0.3753 1
Plasmodium falciparum adenosine deaminase 0.009 0.0167 0.0164
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Plasmodium falciparum V-type K+-independent H+-translocating inorganic pyrophosphatase 0.0405 0.0916 0.0912
Leishmania major vacuolar-type proton translocating pyrophosphatase 1, putative 0.0405 0.0916 0.1483
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0146 0.03 0.0474
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0118 0.0233 0.0522
Echinococcus granulosus acylamino acid releasing enzyme 0.0028 0.0019 0.0042
Entamoeba histolytica AMP deaminase, putative 0.0029 0.0022 0.0027
Brugia malayi hypothetical protein 0.0024 0.001 0.0023
Onchocerca volvulus Alhambra homolog 0.003 0.0024 0.0063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0154 0.032 0.0793
Schistosoma mansoni coup transcription factor 0.003 0.0023 0.0053
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0212 0.0456 0.1023
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0135 0.0132
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0029 0.0022 0.002
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.018 0.0406
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0019 0.0014
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0034 0.0033 0.0037
Trichomonas vaginalis ribokinase, putative 0.0162 0.0338 0.0738
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.006 0.0095 0.0212
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0028 0.0019 0.0043
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0108 0.0209 0.0325
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0098 0.022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0098 0.022
Leishmania major tagatose-6-phosphate kinase-like protein 0.0162 0.0338 0.0537
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0811 0.1881 0.4213
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.021 0.0453 0.0724
Echinococcus granulosus adenosine kinase 0.1424 0.3338 0.7499
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.006 0.0095 0.0212
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0114 0.0223 0.0198
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0023 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0023 0.0052
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0018 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0563 0.1292 0.2902
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0029 0.0064
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0029 0.0022 0.002
Onchocerca volvulus 0.0061 0.0098 0.0259
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0055 0.0055
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0098 0.0219
Schistosoma mansoni ap endonuclease 0.0042 0.0051 0.0115
Schistosoma mansoni carbonyl reductase 0.0024 0.001 0.0023
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0189 0.0401 0.04
Brugia malayi Pre-SET motif family protein 0.0653 0.1506 0.3383
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0024 0.001 0.0023
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0098 0.022
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0044 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus multilocularis tar DNA binding protein 0.0134 0.0271 0.0609
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0098 0.0219
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.021 0.0453 0.0996
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Leishmania major putative PfkB family sugar kinase 0.0162 0.0338 0.0537
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.0095 0.0212
Echinococcus multilocularis musashi 0.0059 0.0092 0.0206
Mycobacterium ulcerans DNA topoisomerase I 0.0212 0.0456 0.0455
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0055
Entamoeba histolytica hypothetical protein 0.0111 0.0216 0.0462
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0098 0.0219
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.001 0.0023
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0055 0.0045
Onchocerca volvulus Serine\/threonine kinase homolog 0.0193 0.0411 0.1094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Schistosoma mansoni adenoreceptor 0.0061 0.0098 0.022
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0015 0.0033
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0098 0.0219
Onchocerca volvulus 0.0061 0.0098 0.0259
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Brugia malayi Cation transporter family protein 0.006 0.0095 0.0212
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.021 0.0453 0.0724
Brugia malayi nuclear receptor NHR-88 0.003 0.0023 0.0052
Echinococcus multilocularis lamin 0.0059 0.0092 0.0206
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0051 0.0041
Onchocerca volvulus 0.0061 0.0098 0.0259
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0018 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0023 0.0052
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0053 0.0079 0.0195
Echinococcus granulosus glycine receptor subunit beta 0.006 0.0095 0.0212
Echinococcus granulosus somatostatin receptor 0.0061 0.0098 0.0219
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0757 0.1753 0.1753
Toxoplasma gondii AMP deaminase 0.0029 0.0022 0.0012
Brugia malayi Melatonin receptor type 1A 0.0061 0.0098 0.0219
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.002 0.0044
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.021 0.0453 0.1016
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0051 0.0115
Mycobacterium ulcerans adenosine deaminase 0.009 0.0167 0.0167
Chlamydia trachomatis DNA gyrase subunit A 0.0655 0.1509 0.1488
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Schistosoma mansoni amine GPCR 0.0061 0.0098 0.022
Echinococcus granulosus single minded 2 0.0036 0.0037 0.0083
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0098 0.0219
Onchocerca volvulus DNA topoisomerase 2 homolog 0.1599 0.3753 1
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.2537 0.5985 0.5985
Leishmania major trypanothione reductase 0.0088 0.0162 0.0248
Echinococcus multilocularis protein dispatched 1 0.0049 0.007 0.0157
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0031 0.0025 0.0022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0051 0.0067
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Giardia lamblia Alanyl dipeptidyl peptidase 0.0028 0.0019 0.002
Echinococcus granulosus death domain containing protein 0.0118 0.0233 0.0522
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.001 0.0023
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0074 0.0127 0.0117
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.006 0.0095 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0162 0.0338 0.0738
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.1892 0.4451 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0193 0.0411 0.0656
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0029 0.0022 0.002
Schistosoma mansoni neurotransmitter gated ion channel 0.0032 0.0029 0.0066
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0316
Entamoeba histolytica prolyl oligopeptidase family protein 0.0028 0.0019 0.0019
Onchocerca volvulus 0.1262 0.2952 0.7866
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0162 0.0338 0.0738
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0098 0.0219
Leishmania major cytochrome p450-like protein 0.0054 0.008 0.0114
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0098 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0145 0.0297 0.0666
Brugia malayi Cation transporter family protein 0.006 0.0095 0.0212
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Plasmodium vivax DNA gyrase subunit B, putative 0.2537 0.5985 0.5981
Echinococcus granulosus carbonyl reductase 1 0.0024 0.001 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0079 0.0112
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0301 0.0476
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0256 0.056 0.056
Echinococcus multilocularis acylamino acid releasing enzyme 0.0028 0.0019 0.0042
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0114 0.0223 0.0499
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0098 0.0219
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.021 0.0453 0.0724
Schistosoma mansoni retinal dehydrogenase 0.0024 0.001 0.0023
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0212 0.0456 0.0729
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0025 0.0024
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0031 0.0025 0.0015
Trichomonas vaginalis helicase, putative 0.0026 0.0015 0.0009
Schistosoma mansoni adenosine deaminase 0.009 0.0167 0.0376
Trichomonas vaginalis set domain proteins, putative 0.0743 0.172 0.3849
Brugia malayi hypothetical protein 0.0162 0.0338 0.0759
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0013 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Onchocerca volvulus 0.0032 0.0029 0.0076
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0044 0.0043
Trypanosoma brucei ribokinase, putative 0.0162 0.0338 0.0537
Echinococcus granulosus lamin dm0 0.0059 0.0092 0.0206
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0042 0.0052 0.0117
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0024 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0098 0.022
Echinococcus granulosus lamin 0.0059 0.0092 0.0206
Loa Loa (eye worm) glutathione reductase 0.0088 0.0162 0.0363
Loa Loa (eye worm) dehydrogenase 0.0024 0.001 0.0023
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0055 0.0055
Brugia malayi kinase, mitochondrial precursor 0.0114 0.0223 0.0499
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0056 0.0125
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0022 0.002
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0024 0.001 0.0023
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0015 0.0005
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.009 0.0167 0.0167
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0023 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0055 0.0073
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0063 0.0119
Echinococcus granulosus carbonyl reductase 1 0.0024 0.001 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0162 0.0337 0.0756
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.0095 0.0212
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.006 0.0095 0.0212
Onchocerca volvulus 0.0061 0.0098 0.0259
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0757 0.1753 0.2854
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0098 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Entamoeba histolytica DNA topoisomerase III, putative 0.0212 0.0456 0.1003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0319
Onchocerca volvulus 0.0024 0.001 0.0026
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Trichomonas vaginalis ribokinase, putative 0.0162 0.0338 0.0738
Trypanosoma brucei polo-like protein kinase 0.0193 0.0411 0.0656
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0108 0.0209 0.0325
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0098 0.0219
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.021 0.0453 0.0449
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Mycobacterium ulcerans beta-lactamase 0.0038 0.0044 0.0043
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0845 0.1962 0.4873
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0309
Echinococcus multilocularis transcription factor btf3 0.0111 0.0216 0.0484
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0051 0.0026
Entamoeba histolytica serine/threonine protein kinase, putative 0.0193 0.0411 0.0902
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0757 0.1753 0.2854
Plasmodium falciparum steroid dehydrogenase, putative 0.0024 0.001 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0055 0.0123
Loa Loa (eye worm) hypothetical protein 0.0134 0.027 0.0607
Brugia malayi hypothetical protein 0.0028 0.0018 0.004
Mycobacterium ulcerans endonuclease IV 0.0077 0.0135 0.0135
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0092 0.0206
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0051 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0098 0.0219
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0022 0.002
Echinococcus multilocularis cpg binding protein 0.0122 0.0242 0.0543
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0044 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Schistosoma mansoni phd/f-box containing protein 0.0108 0.0209 0.0469
Brugia malayi RE15519p 0.0061 0.0098 0.0219
Chlamydia trachomatis DNA gyrase subunit B 0.1837 0.432 0.4305
Mycobacterium leprae Probable oxidoreductase 0.0024 0.001 0.0024
Trypanosoma brucei DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Schistosoma mansoni glutaminase 0.0269 0.0592 0.133
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.006 0.0095 0.0212
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0024 0.001 0.001
Schistosoma mansoni protein phosphatase 2C 0.0108 0.0209 0.0469
Plasmodium falciparum DNA gyrase subunit A 0.4226 1 1
Schistosoma mansoni opsin-like receptor 0.0061 0.0098 0.022
Entamoeba histolytica heat shock protein 90, putative 0.0114 0.0223 0.0478
Echinococcus granulosus protein prenyltransferase alpha subunit 0.021 0.0453 0.1016
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.018 0.0405
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.021 0.0453 0.0724
Plasmodium falciparum phd finger protein, putative 0.003 0.0024 0.0021
Giardia lamblia Rab geranylgeranyltransferase 0.021 0.0453 0.106
Loa Loa (eye worm) hypothetical protein 0.0145 0.0297 0.0666
Trypanosoma cruzi Heat shock protein 83, putative 0.0114 0.0223 0.0347
Plasmodium falciparum flap endonuclease 1 0.0026 0.0015 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0088 0.0162 0.0363
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0098 0.0219
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0033 0.0073
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0052 0.0117
Loa Loa (eye worm) hypothetical protein 0.0118 0.0233 0.0522
Brugia malayi TAR-binding protein 0.0134 0.0271 0.0609
Schistosoma mansoni peptidase Clp (S14 family) 0.0154 0.032 0.0718
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0024 0.001 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0044 0.0098
Loa Loa (eye worm) CXXC zinc finger family protein 0.0115 0.0227 0.0508
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.2537 0.5985 0.5981
Treponema pallidum replicative DNA helicase (dnaB) 0.0393 0.0887 0.0864
Leishmania major AMP deaminase, putative 0.0029 0.0022 0.002
Giardia lamblia DNA topoisomerase III 0.0212 0.0456 0.1068
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Schistosoma mansoni rotamase 0.0034 0.0033 0.0074
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0045 0.0101
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.002 0.0044
Plasmodium falciparum heat shock protein 90 0.0114 0.0223 0.0219
Toxoplasma gondii heat shock protein 90, putative 0.0114 0.0223 0.0212
Entamoeba histolytica kinase, PfkB family 0.0162 0.0338 0.0738
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Trypanosoma brucei DNA topoisomerase II beta, putative 0.1681 0.3948 0.6449
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0114 0.0223 0.0499
Loa Loa (eye worm) hypothetical protein 0.0059 0.0092 0.0206
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0114 0.0223 0.0212
Echinococcus granulosus AMP deaminase 2 0.0029 0.0022 0.005
Mycobacterium ulcerans hypothetical protein 0.0163 0.034 0.034
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0001 0.0001
Loa Loa (eye worm) beta-lactamase 0.0038 0.0044 0.0098
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0024 0.001 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Chlamydia trachomatis DNA topoisomerase I 0.0212 0.0456 0.0432
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0191 0.0408 0.0915
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0055 0.0135
Schistosoma mansoni flap endonuclease-1 0.0024 0.0009 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Schistosoma mansoni hypothetical protein 0.0042 0.0052 0.0117
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.001 0.0023
Toxoplasma gondii NAC domain-containing protein 0.0111 0.0216 0.0206
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0114 0.0223 0.0552
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Onchocerca volvulus 0.0061 0.0098 0.0259
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Trichomonas vaginalis rotamase, putative 0.0034 0.0033 0.005
Trichomonas vaginalis esterase, putative 0.0038 0.0044 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.018 0.0381
Schistosoma mansoni serine/threonine protein kinase 0.002 0 0.0001
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0067 0.0111 0.0164
Echinococcus multilocularis conserved hypothetical protein 0.0024 0.001 0.0023
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0154 0.032 0.0717
Toxoplasma gondii endonuclease IV APN 0.0077 0.0135 0.0125
Schistosoma mansoni single-minded 0.0048 0.0067 0.0151
Onchocerca volvulus 0.0024 0.001 0.0026
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0067 0.0111 0.0274
Echinococcus granulosus steroid dehydrogenase 0.0024 0.001 0.0023
Brugia malayi CXXC zinc finger family protein 0.0115 0.0227 0.0508
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0098 0.0219
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 1 0.0405 0.0916 0.1483
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Loa Loa (eye worm) LGC-31 protein 0.006 0.0095 0.0212
Plasmodium vivax heat shock protein 86, putative 0.0114 0.0223 0.0212
Toxoplasma gondii thioredoxin reductase 0.0088 0.0162 0.0152
Echinococcus multilocularis nAChR subunit 0.0032 0.0029 0.0065
Brugia malayi Cation transporter family protein 0.006 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0055 0.0055
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.018 0.0405
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0023 0.0052
Trichomonas vaginalis rotamase, putative 0.0033 0.0031 0.0046
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0044 0.0075
Leishmania major hypothetical protein, conserved 0.0029 0.0022 0.002
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0022 0.002
Trypanosoma brucei DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Leishmania major mitochondrial DNA topoisomerase II 0.2593 0.6116 1
Brugia malayi Dopamine receptor protein 2 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0114 0.0223 0.0222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Echinococcus granulosus sex peptide receptor 0.0061 0.0098 0.0219
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0118 0.0233 0.0522
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Schistosoma mansoni ankyrin 23/unc44 0.0118 0.0233 0.0522
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Brugia malayi hypothetical protein 0.0028 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Plasmodium vivax vacuolar-type H+ pumping pyrophosphatase, putative 0.0405 0.0916 0.0906
Schistosoma mansoni endoplasmin 0.0114 0.0223 0.05
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0024 0.0014
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.006 0.0095 0.0212
Leishmania major adenosine kinase-like protein 0.0162 0.0338 0.0537
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.4226 1 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Brugia malayi CHE-14 protein 0.0043 0.0056 0.0124
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.006 0.0095 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0056 0.0102
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) acetylcholine receptor protein 0.0028 0.0018 0.004
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0055 0.0055
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0055 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0023 0.0052
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable dehydrogenase 0.0024 0.001 0.001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0098 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.0453 0.0724
Mycobacterium ulcerans dehydrogenase/reductase 0.0024 0.001 0.001
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3446 0.8146 0.8146
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Schistosoma mansoni cpg binding protein 0.0122 0.0242 0.0544
Schistosoma mansoni hypothetical protein 0.1641 0.3855 0.866
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.006 0.0095 0.0212
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.0024
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0024 0.001 0.0007
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0118 0.0233 0.0522
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.2537 0.5985 0.5975
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0063 0.0053
Brugia malayi heat shock protein 90 0.0114 0.0223 0.0499
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0212 0.0456 0.1024
Trypanosoma cruzi vacuolar-type proton translocating pyrophosphatase 1 0.0405 0.0916 0.1483
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Toxoplasma gondii prolyl endopeptidase 0.0146 0.03 0.029
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0212 0.0456 0.0446
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0055 0.0055
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0067 0.0111 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0055
Onchocerca volvulus Ribokinase homolog 0.0162 0.0338 0.09
Plasmodium vivax SET domain protein, putative 0.0096 0.018 0.017
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.017 0.0382
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0098 0.0219
Schistosoma mansoni hypothetical protein 0.0061 0.0098 0.022
Trypanosoma cruzi squalene synthase, putative 0.0605 0.1392 0.2262
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0191 0.0408 0.0916
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0097 0.0218
Plasmodium falciparum AMP deaminase, putative 0.0029 0.0022 0.0019
Trypanosoma brucei squalene synthase, putative 0.0605 0.1392 0.2262
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0023 0.0052
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0023 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.002 0 0.0001
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.006 0.0095 0.0212
Plasmodium vivax V-type H(+)-translocating pyrophosphatase, putative 0.0405 0.0916 0.0906
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0027 0.006
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.0102
Schistosoma mansoni neuropeptide receptor 0.0061 0.0098 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0411 0.0902
Loa Loa (eye worm) hypothetical protein 0.0061 0.0097 0.0218
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0063 0.0102 0.0229
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.4226 1 1
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.1681 0.3948 0.6449
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0044 0.0043
Toxoplasma gondii NADPH-glutathione reductase 0.0031 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Onchocerca volvulus 0.0024 0.001 0.0026
Brugia malayi Cytochrome P450 family protein 0.0054 0.008 0.018
Chlamydia trachomatis replicative DNA helicase 0.0393 0.0887 0.0864
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0135 0.0135
Leishmania major hypothetical protein, conserved 0.0114 0.0223 0.0347
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0098 0.0219
Brugia malayi beta-lactamase family protein 0.0038 0.0044 0.0098
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus intermediate filament protein 0.0059 0.0092 0.0206
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.0095 0.0212
Brugia malayi DNA topoisomerase III beta-1 0.0212 0.0456 0.1023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.006 0.0095 0.0213
Trypanosoma brucei adenosine kinase, putative 0.1424 0.3338 0.545
Echinococcus granulosus WW domain containing oxidoreductase 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Loa Loa (eye worm) prolyl oligopeptidase 0.0028 0.0019 0.0042
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0031 0.0025 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.017 0.0382
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0098 0.0219
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0114 0.0223 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Trypanosoma cruzi DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0098 0.022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0018 0.004
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0044 0.0098
Echinococcus granulosus Ankyrin 0.0118 0.0233 0.0522
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0023 0.0052
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0098 0.0219
Echinococcus granulosus peptidase Clp S14 family 0.0101 0.0193 0.0433
Schistosoma mansoni histamine h1 receptor 0.0061 0.0098 0.022
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0015 0.0011
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0212 0.0456 0.0729
Entamoeba histolytica fructokinase, putative 0.0162 0.0338 0.0738
Loa Loa (eye worm) hypothetical protein 0.0732 0.1693 0.3803
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0757 0.1753 0.2854
Onchocerca volvulus 0.0061 0.0098 0.0259
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus granulosus Dipeptidyl peptidase 9 0.0074 0.0127 0.0285
Echinococcus granulosus prolyl endopeptidase 0.0146 0.03 0.0673
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.0219 0.0491
Plasmodium falciparum JmjC domain-containing protein, putative 0.0108 0.0209 0.0206
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0031 0.0021
Mycobacterium ulcerans oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0114 0.0223 0.0478
Onchocerca volvulus Prolyl endopeptidase homolog 0.0146 0.03 0.0798
Loa Loa (eye worm) hypothetical protein 0.0811 0.1881 0.4226
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0301 0.0476
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0098 0.0219
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Onchocerca volvulus 0.006 0.0095 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0216 0.0462
Mycobacterium leprae Probable adenosine kinase adk 0.0162 0.0338 0.0839
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0193 0.0432
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0241 0.0541
Brugia malayi Dopamine receptor 0.0061 0.0098 0.0219
Trichomonas vaginalis receptor histidine kinase, putative 0.0114 0.0223 0.0478
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.0318 0.0714
Echinococcus granulosus DNA topoisomerase 2 alpha 0.1892 0.4451 1
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0033 0.0037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Mycobacterium ulcerans dehydrogenase 0.0024 0.001 0.001
Brugia malayi beta-lactamase 0.0038 0.0044 0.0098
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0067 0.0111 0.0164
Brugia malayi jmjC domain containing protein 0.0108 0.0209 0.0469
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0022 0.002
Trypanosoma cruzi AMP deaminase 2, putative 0.0029 0.0022 0.002
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0098 0.0219
Trypanosoma cruzi transcription factor btf3, putative 0.0111 0.0216 0.0336
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0055 0.0055
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0055 0.0055
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0098 0.0219
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Schistosoma mansoni patched 1 0.0043 0.0056 0.0125
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.001 0.001
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0098 0.0219
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0136 0.0277 0.0436
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0134 0.0271 0.0609
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0098 0.022
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Loa Loa (eye worm) ICD-1 protein 0.0111 0.0216 0.0484
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0054
Schistosoma mansoni thyroid hormone receptor 0.003 0.0023 0.0053
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0098 0.022
Echinococcus granulosus nAChR subunit 0.006 0.0095 0.0212
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0098 0.0219
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.006 0.0095 0.0212
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0023 0.0052
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0212 0.0456 0.1131
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.001 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0023 0.0052
Onchocerca volvulus 0.0024 0.001 0.0026
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0101 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0019 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0256 0.056 0.056
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.006 0.0095 0.0212
Brugia malayi Cytochrome P450 family protein 0.0043 0.0055 0.0123
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0056
Echinococcus granulosus nAChR subunit 0.0032 0.0029 0.0065
Onchocerca volvulus Huntingtin homolog 0.0134 0.027 0.0719
Schistosoma mansoni transcription factor btf3 0.0111 0.0216 0.0485
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0055 0.0055
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0051 0.0115
Brugia malayi Pre-SET motif family protein 0.0096 0.018 0.0405
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0033 0.0037
Brugia malayi Dehydrogenases, short chain protein 2 0.0024 0.001 0.0023
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0653 0.1506 0.3383
Leishmania major adenosine kinase-like protein 0.0162 0.0338 0.0537
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0063 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0019 0.0042
Brugia malayi glutathione reductase 0.0088 0.0162 0.0363
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0678 0.1522
Brugia malayi Probable ClpP-like protease 0.0154 0.032 0.0717
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.018 0.0406
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0136 0.0277 0.0621
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0045 0.0101
Loa Loa (eye worm) hypothetical protein 0.0101 0.0193 0.0432
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0154 0.032 0.0717
Trypanosoma cruzi DNA topoisomerase II, putative 0.1681 0.3948 0.6449
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0055 0.0055
Onchocerca volvulus Putative pyridoxal kinase 0.0162 0.0338 0.09
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.006 0.0095 0.0212
Brugia malayi Dopamine receptor protein 1 0.0915 0.2128 0.4781
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0029 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0055 0.0055
Brugia malayi GnHR receptor homolog 0.0061 0.0098 0.0219
Onchocerca volvulus 0.0059 0.0092 0.0243
Onchocerca volvulus 0.0024 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0098 0.022
Schistosoma mansoni carbonyl reductase 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0114 0.0223 0.0499
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0114 0.0223 0.0478
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0028 0.0019 0.0014
Echinococcus granulosus neuropeptide receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis protein patched 0.0043 0.0056 0.0124
Schistosoma mansoni hypothetical protein 0.0061 0.0098 0.022
Schistosoma mansoni nuclear hormone receptor 0.003 0.0023 0.0053
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0024 0.0014
Onchocerca volvulus 0.006 0.0095 0.0251
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0098 0.0219
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0015 0.0005
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0136 0.0277 0.0621
Mycobacterium ulcerans DNA gyrase subunit A 0.4226 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Schistosoma mansoni lamin 0.0059 0.0092 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0216 0.0462
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0051 0.0067
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0114 0.0223 0.0219
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0098 0.0219
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0025 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0689 0.1111
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0023 0.0061
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0098 0.022
Echinococcus multilocularis ribokinase 0.0162 0.0338 0.0759
Schistosoma mansoni cytochrome P450 0.0043 0.0055 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.4226 1 1
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.006 0.0095 0.0212
Leishmania major protein farnesyltransferase alpha subunit, putative 0.021 0.0453 0.0724
Loa Loa (eye worm) hypothetical protein 0.0028 0.0019 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Trypanosoma cruzi squalene synthase, putative 0.0605 0.1392 0.2262
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0032 0.0029 0.0065
Loa Loa (eye worm) hypothetical protein 0.0123 0.0245 0.0549
Brugia malayi hypothetical protein 0.0134 0.027 0.0607
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.006 0.0095 0.0212
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0025 0.0024
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0074 0.0127 0.0285
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0329 0.0738
Schistosoma mansoni AMP deaminase 0.0029 0.0022 0.005
Echinococcus granulosus expressed conserved protein 0.0095 0.0178 0.0399
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0271 0.061
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0811 0.1881 0.4226
Onchocerca volvulus 0.0028 0.0018 0.0047
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3163 0.7472 0.7472
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0023 0.0053
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0114 0.0225 0.0504
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0162 0.0338 0.0759
Brugia malayi steroid hormone receptor 0.003 0.0023 0.0052
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0018 0.004
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0031 0.0025 0.0024
Trichomonas vaginalis ribokinase, putative 0.0162 0.0338 0.0738
Echinococcus multilocularis netrin receptor unc 5 0.0118 0.0233 0.0522
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0757 0.1753 0.1753
Echinococcus granulosus neuropeptide receptor A26 0.0563 0.1292 0.2902
Brugia malayi prolyl oligopeptidase family protein 0.0191 0.0408 0.0915
Loa Loa (eye worm) hypothetical protein 0.0096 0.018 0.0405
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.008 0.018
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0044
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0329 0.0738
Onchocerca volvulus 0.003 0.0023 0.0061
Brugia malayi Dehydrogenases, short chain protein 30 0.0024 0.001 0.0023
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0114 0.0223 0.0222
Mycobacterium ulcerans fructokinase, PfkB 0.0162 0.0338 0.0338
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0023 0.0052
Onchocerca volvulus 0.0024 0.001 0.0026
Echinococcus multilocularis Ankyrin 0.0118 0.0233 0.0522
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0097 0.0218
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Echinococcus granulosus hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi prolyl oligopeptidase family protein 0.0074 0.0127 0.0285
Echinococcus granulosus FTZ F1 alpha 0.003 0.0023 0.0052
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0811 0.1881 0.4226
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0023 0.0052
Onchocerca volvulus 0.0029 0.0022 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0023 0.0052
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0098 0.0219
Onchocerca volvulus 0.0038 0.0044 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0029 0.0022 0.002
Plasmodium falciparum DNA topoisomerase 3, putative 0.0212 0.0456 0.0452
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0393 0.0887 0.0877
Brugia malayi oxidoreductase 0.0024 0.001 0.0023
Leishmania major DNA topoisomerase ii 0.1681 0.3948 0.6449
Plasmodium falciparum thioredoxin reductase 0.0031 0.0025 0.0022
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0051 0.0051
Brugia malayi Uncoordinated protein 44 0.0118 0.0233 0.0522
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0031 0.0025 0.0015
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0114 0.0223 0.0222
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0074 0.0127 0.0192
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0028 0.0018 0.004
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0098 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0601 0.1381 0.3087
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0029 0.0064
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0305 0.0678 0.1522
Onchocerca volvulus 0.0038 0.0044 0.0115
Loa Loa (eye worm) ACC-1 protein 0.006 0.0095 0.0212
Plasmodium vivax endoplasmin, putative 0.0114 0.0223 0.0212
Plasmodium vivax glutathione reductase, putative 0.0088 0.0162 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Brugia malayi hypothetical protein 0.0028 0.0018 0.004
Trichomonas vaginalis adenosine deaminase, putative 0.009 0.0167 0.0353
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0029 0.0064
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0031 0.0025 0.0022
Toxoplasma gondii V-type H(+)-translocating pyrophosphatase VP1 0.0405 0.0916 0.0906
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.001 0.001
Plasmodium falciparum endoplasmin, putative 0.0114 0.0223 0.0219
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0098 0.0219
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0028 0.0018 0.004
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0028 0.0019 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0114 0.0223 0.0478
Trypanosoma cruzi transcription factor btf3, putative 0.0111 0.0216 0.0336
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0023 0.0052
Mycobacterium ulcerans two component sensor kinase MprB 0.0114 0.0223 0.0222
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0015 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0114 0.0223 0.0222
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0256 0.056 0.0901
Echinococcus granulosus muscleblind protein 0.0305 0.0678 0.1522
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0015 0.0009
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0055 0.0055
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Echinococcus multilocularis lamin dm0 0.0059 0.0092 0.0206
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0054 0.0098
Loa Loa (eye worm) dehydrogenase 0.0024 0.001 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.0095 0.0212
Schistosoma mansoni heat shock protein 0.0114 0.0223 0.05
Loa Loa (eye worm) cytochrome P450 0.0043 0.0055 0.0123
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.008 0.0114
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Schistosoma mansoni biogenic amine receptor 0.0061 0.0098 0.022
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Trypanosoma brucei transcription factor BTF3, putative 0.0111 0.0216 0.0336
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0024 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.0061 0.0098 0.022
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0114 0.0223 0.0212
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0023 0.0052
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0067 0.0111 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.018 0.0381
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.008 0.0114
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0098 0.0219
Schistosoma mansoni thyroid hormone receptor 0.003 0.0023 0.0053
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.008 0.018
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.017 0.0382
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Onchocerca volvulus DNA topoisomerase 2 homolog 0.1599 0.3753 1
Brugia malayi adenosine monophosphate deaminase 0.0029 0.0022 0.005
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0154 0.032 0.0309
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0098 0.022
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0118 0.0234 0.0233
Giardia lamblia NADH oxidase lateral transfer candidate 0.0031 0.0025 0.0035
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.021 0.0453 0.0724
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0028 0.0018 0.004
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0191 0.0408 0.1084
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0098 0.0219
Schistosoma mansoni neuropeptide receptor 0.0061 0.0098 0.022
Echinococcus multilocularis AMP deaminase 2 0.0029 0.0022 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0089 0.0163 0.0366
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0098 0.0219
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0212 0.0456 0.1023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0053 0.0079 0.0069
Echinococcus multilocularis rho GTPase activating protein 20 0.0212 0.0456 0.1023
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0028 0.0018 0.004
Onchocerca volvulus 0.0038 0.0044 0.0115
Brugia malayi neuropeptide F receptor 0.0061 0.0098 0.0219
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0044 0.0107
Leishmania major mitochondrial DNA polymerase beta 0.031 0.0689 0.1111
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0079 0.0075
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0037 0.0083
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0028 0.0018 0.004
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0018 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.017 0.0382
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.021 0.0453 0.0443
Loa Loa (eye worm) hypothetical protein 0.0134 0.027 0.0607
Loa Loa (eye worm) hypothetical protein 0.1424 0.3338 0.7499
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0146 0.03 0.0674
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0023 0.0052
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Onchocerca volvulus Putative nachr subunit 0.006 0.0095 0.0251
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0098 0.0219
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0212 0.0456 0.1023
Brugia malayi Fli-1 protein 0.0224 0.0484 0.1087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0098 0.0219
Trypanosoma brucei Heat shock protein 83, putative 0.0114 0.0223 0.0347
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0212 0.0456 0.0446
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Onchocerca volvulus 0.006 0.0095 0.0251
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.006 0.0095 0.0212
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0135 0.0335
Schistosoma mansoni steroid dehydrogenase 0.0024 0.001 0.0023
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0162 0.0338 0.0759
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0033 0.0073
Brugia malayi PAS domain containing protein 0.0048 0.0067 0.015
Brugia malayi DNA topoisomerase II, alpha isozyme 0.1892 0.4451 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.006 0.0095 0.0212
Plasmodium vivax adenosine deaminase, putative 0.009 0.0167 0.0157
Brugia malayi hypothetical protein 0.0061 0.0098 0.0219
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0128 0.0286
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0055 0.0055
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0114 0.0223 0.0222
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0136 0.0277 0.0276
Brugia malayi AKH receptor 0.0061 0.0098 0.0219
Echinococcus granulosus orexin receptor type 2 0.0061 0.0098 0.0219
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0024 0.001 0.0023
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0154 0.032 0.0717
Onchocerca volvulus 0.021 0.0453 0.1205
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0044 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0031 0.0034
Trichomonas vaginalis mercuric reductase, putative 0.0031 0.0025 0.0033
Brugia malayi Retinol dehydrogenase 12 0.0024 0.001 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Brugia malayi sulfakinin receptor protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.021 0.0453 0.1016
Echinococcus granulosus netrin receptor unc 5 0.0118 0.0233 0.0522
Brugia malayi jmjC domain containing protein 0.0108 0.0209 0.0469
Echinococcus multilocularis G protein coupled receptor 139 0.0061 0.0098 0.0219
Schistosoma mansoni short chain dehydrogenase 0.0024 0.001 0.0023
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0045 0.0101
Mycobacterium leprae Probable two component sensor kinase MprB 0.0114 0.0223 0.0552
Trichomonas vaginalis sensor histidine kinase, putative 0.0114 0.0223 0.0478
Brugia malayi jmjC domain containing protein 0.0108 0.0209 0.0469
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0101 0.0193 0.0193
Leishmania major cytochrome p450-like protein 0.0043 0.0055 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0023 0.0052
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0028 0.0018 0.004
Schistosoma mansoni amine GPCR 0.0061 0.0098 0.022
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Schistosoma mansoni nAChR subunit 0.006 0.0095 0.0213
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0024 0.0054
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0044 0.0098
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0098 0.0219
Schistosoma mansoni gabp alpha 0.0074 0.0128 0.0287
Schistosoma mansoni ets-related 0.0224 0.0484 0.1087
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0029 0.0066
Leishmania major DNA topoisomerase III, putative 0.0212 0.0456 0.0729
Treponema pallidum recombinase A 0.011 0.0213 0.0189
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0031 0.0025 0.0024
Mycobacterium leprae Conserved hypothetical protein 0.1159 0.2707 0.6725
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0256 0.056 0.1258
Loa Loa (eye worm) hypothetical protein 0.0043 0.0056 0.0124
Brugia malayi follicle stimulating hormone receptor 0.0312 0.0695 0.156
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0393 0.0887 0.0886
Loa Loa (eye worm) hypothetical protein 0.0053 0.0079 0.0176
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0028 0.0019 0.0043
Mycobacterium ulcerans hypothetical protein 0.0038 0.0044 0.0043
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0055 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0044 0.0075
Onchocerca volvulus 0.0061 0.0098 0.0259
Schistosoma mansoni aldehyde dehydrogenase 0.0256 0.056 0.1259
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0154 0.032 0.0319
Echinococcus multilocularis expressed protein 0.0034 0.0033 0.0073
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0024 0.001 0.0023
Trichomonas vaginalis heat shock protein, putative 0.0114 0.0223 0.0478
Brugia malayi cytochrome P450 0.0043 0.0055 0.0123
Echinococcus multilocularis serotonin receptor 0.0061 0.0098 0.0219
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0055 0.0055
Schistosoma mansoni biogenic amine receptor 0.0061 0.0098 0.022
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0098 0.0219
Echinococcus granulosus dnaJ subfamily B 0.1641 0.3855 0.866
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0024 0.001 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0019 0.0014
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0212
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0074 0.0127 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.006 0.0095 0.0213
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0022 0.002
Schistosoma mansoni hypothetical protein 0.053 0.1212 0.2722
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0024 0.001 0.0023
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0024 0.001 0.001
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0024 0.001 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0044 0.0075
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0031 0.0025 0.0024
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0065
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0024 0.001 0.001
Brugia malayi Protein kinase domain containing protein 0.0118 0.0234 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0044 0.0098
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.021 0.0453 0.1017
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.001 0.001
Treponema pallidum DNA topoisomerase I (topA) 0.0212 0.0456 0.0432
Echinococcus multilocularis lysine specific demethylase 6a 0.0108 0.0209 0.0469
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0044 0.0098
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.0102
Brugia malayi prolyl oligopeptidase family protein 0.0028 0.0019 0.0042
Schistosoma mansoni amine GPCR 0.0061 0.0098 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Brugia malayi Bromodomain containing protein 0.0034 0.0033 0.0074
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0024 0.001 0.0024
Trichomonas vaginalis endoplasmin, putative 0.0114 0.0223 0.0478
Loa Loa (eye worm) hypothetical protein 0.015 0.0309 0.0693
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0098 0.0219
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0055 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0025 0.0024
Schistosoma mansoni cpg binding protein 0.0115 0.0227 0.0509
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.1713 0.4025 1
Loa Loa (eye worm) glutaminase 0.0269 0.0592 0.1329
Leishmania major oligopeptidase b 0.0067 0.0111 0.0164
Trypanosoma brucei heat shock protein, putative 0.0114 0.0223 0.0347
Entamoeba histolytica transcription factor BTF3, putative 0.0111 0.0216 0.0462
Schistosoma mansoni hypothetical protein 0.0042 0.0052 0.0117
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0018 0.004
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0193 0.0411 0.0923
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0136 0.0277 0.0622
Toxoplasma gondii aldehyde dehydrogenase 0.0256 0.056 0.0551
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0022 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.018 0.0405
Mycobacterium tuberculosis Ribokinase RbsK 0.0162 0.0338 0.0338
Loa Loa (eye worm) oxidoreductase 0.0024 0.001 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0411 0.093 0.2089
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0051 0.0098
Entamoeba histolytica AMP deaminase, putative 0.0029 0.0022 0.0027
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0019 0.0019
Leishmania major heat shock protein 83-1 0.0114 0.0223 0.0347
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0098 0.022
Brugia malayi intermediate filament protein 0.0059 0.0092 0.0206
Mycobacterium ulcerans DNA gyrase subunit B 0.2537 0.5985 0.5985
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.006 0.0095 0.0212
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0023 0.0052
Echinococcus granulosus neuropeptide s receptor 0.0563 0.1292 0.2902
Onchocerca volvulus 0.0212 0.0456 0.1213
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.009 0.0167 0.0157
Schistosoma mansoni hypothetical protein 0.0042 0.0052 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0061 0.0098 0.0219
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0108 0.0209 0.0325
Echinococcus granulosus serotonin receptor 0.0061 0.0098 0.0219
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Echinococcus multilocularis heat shock protein 90 0.0114 0.0223 0.0499
Trypanosoma brucei prolyl endopeptidase 0.0146 0.03 0.0474
Plasmodium vivax hypothetical protein, conserved 0.0114 0.0223 0.0212
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0193 0.0411 0.0923
Brugia malayi RNA binding protein 0.0134 0.0271 0.0609
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0811 0.1881 0.1873
Trichomonas vaginalis DNA topoisomerase II, putative 0.1892 0.4451 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0233 0.0522
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0098 0.022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.2593 0.6116 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0028 0.0019 0.0019
Brugia malayi Probable DNA topoisomerase II 0.1892 0.4451 1
Schistosoma mansoni jumonji domain containing protein 0.0446 0.1014 0.2278
Echinococcus granulosus expressed protein 0.038 0.0855 0.192
Brugia malayi GRF zinc finger family protein 0.0212 0.0456 0.1023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0044 0.0043
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0011 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0098 0.0219
Schistosoma mansoni kinase 0.0098 0.0186 0.0417
Mycobacterium tuberculosis Conserved protein 0.0038 0.0044 0.0043
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0162 0.0338 0.0738
Echinococcus multilocularis prolyl endopeptidase 0.0146 0.03 0.0673
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0098 0.0219
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0051 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.001 0.0023
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.0095 0.0212
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0098 0.0219

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.03 ug ml-1 Antifungal activity against Candida albicans ChEMBL. 16260134
MIC (functional) = 0.03 ug ml-1 Antifungal activity against Candida albicans ChEMBL. 16260134
MIC (functional) = 0.08 ug ml-1 Antifungal activity against Aspergillus species ChEMBL. 16260134

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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