Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | adenosine kinase | 0.0551 | 1 | 0.5 |
Leishmania major | adenosine kinase, putative | 0.0551 | 1 | 0.5 |
Echinococcus multilocularis | adenosine kinase | 0.0551 | 1 | 0.5 |
Schistosoma mansoni | adenosine kinase | 0.0551 | 1 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0551 | 1 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0551 | 1 | 0.5 |
Trypanosoma brucei | adenosine kinase, putative | 0.0551 | 1 | 0.5 |
Onchocerca volvulus | 0.0488 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0551 | 1 | 0.5 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0551 | 1 | 0.5 |
Echinococcus granulosus | adenosine kinase | 0.0551 | 1 | 0.5 |
Trypanosoma brucei | adenosine kinase, putative | 0.0551 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 24 % | Inhibition of Plasmodium falciparum CQ-resistant strain FcB1 growth at 1 uM | ChEMBL. | 16263280 |
Inhibition (functional) | = 24 % | Inhibition of Plasmodium falciparum CQ-resistant strain FcB1 growth at 1 uM | ChEMBL. | 16263280 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.