Detailed information for compound 349122

Basic information

Technical information
  • TDR Targets ID: 349122
  • Name: 2-[3-[7-(trifluoromethyl)imidazo[1,2-a]pyrimi din-3-yl]phenyl]benzonitrile
  • MW: 364.323 | Formula: C20H11F3N4
  • H donors: 0 H acceptors: 3 LogP: 5.04 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccccc1c1cccc(c1)c1cnc2n1ccc(n2)C(F)(F)F
  • InChi: 1S/C20H11F3N4/c21-20(22,23)18-8-9-27-17(12-25-19(27)26-18)14-6-3-5-13(10-14)16-7-2-1-4-15(16)11-24/h1-10,12H
  • InChiKey: VYBPWFTWAKMZPZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[3-[7-(trifluoromethyl)-3-imidazo[1,2-a]pyrimidinyl]phenyl]benzonitrile
  • 2-[3-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]phenyl]benzenecarbonitrile
  • 2-[3-[7-(trifluoromethyl)imidazo[3,2-a]pyrimidin-3-yl]phenyl]benzonitrile
  • 2-[3-[7-(trifluoromethyl)-3-imidazo[3,2-a]pyrimidinyl]phenyl]benzonitrile

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 5 References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131775 All targets in OG5_131775
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor Get druggable targets OG5_129441 All targets in OG5_129441
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, beta 3 473 aa 441 aa 29.9 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, alpha 1 456 aa 451 aa 30.2 %
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, alpha 3 492 aa 437 aa 28.8 %
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, alpha 5 462 aa 447 aa 28.0 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, gamma 2 467 aa 449 aa 27.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0034 0.0034
Trypanosoma brucei caltractin, putative 0.0112 0.0323 0.0619
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0301 0.0948 0.2387
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0079 0.0215 0.0503
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0174 0.017
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0103 0.0295 0.0707
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0103 0.0295 0.0295
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0301 0.0948 0.0944
Echinococcus granulosus glycine receptor subunit beta 0.0075 0.0203 0.0203
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0035 0.0069 0.0069
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0065 0.0123
Trichomonas vaginalis calcineurin B subunit, putative 0.0106 0.0304 0.0728
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.008 0.0159
Onchocerca volvulus 0.0024 0.0034 0.0085
Onchocerca volvulus 0.003 0.0053 0.0133
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1698 0.5554 0.5552
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Onchocerca volvulus 0.0035 0.0069 0.0175
Echinococcus granulosus nAChR subunit 0.0075 0.0203 0.0203
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.008 0.0848
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0053 0.0053
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0034 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0301 0.0948 0.2387
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0668 0.0652
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0034 0.0034
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0301 0.0948 0.2363
Mycobacterium tuberculosis Conserved protein 0.0038 0.008 0.0848
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Echinococcus granulosus dna polymerase kappa 0.002 0.0022 0.0022
Giardia lamblia Cysteine protease 0.0301 0.0948 0.2498
Echinococcus granulosus glycoprotein Antigen 5 0.004 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0082
Brugia malayi AKH receptor 0.0024 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Echinococcus granulosus Ankyrin 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Schistosoma mansoni hypothetical protein 0.0064 0.0164 0.016
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0065 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0708 0.2289 0.4386
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0022 0.0074
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0037 0.0076 0.0076
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0036 0.0036
Toxoplasma gondii cathepsin CPL 0.1214 0.3958 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0301 0.0948 0.0933
Loa Loa (eye worm) hypothetical protein 0.1266 0.413 0.413
Schistosoma mansoni reticulocalbin 0.0103 0.0295 0.029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0034 0.0034
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Echinococcus granulosus tachykinin peptides receptor 99D 0.1793 0.5869 0.5869
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0075 0.0203 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0025 0.0025
Schistosoma mansoni calmodulin 0.0103 0.0295 0.029
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0065 0.0159
Onchocerca volvulus Cathepsin F homolog 0.1214 0.3958 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Schistosoma mansoni opsin-like receptor 0.0024 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Onchocerca volvulus 0.003 0.0055 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0295 0.0705
Echinococcus multilocularis cathepsin L cysteine protease 0.1214 0.3958 0.3958
Entamoeba histolytica calmodulin, putative 0.0103 0.0295 0.0707
Echinococcus granulosus neuropeptide receptor 0.0024 0.0034 0.0034
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0216 0.0668 0.1283
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.006 0.0153 0.0344
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0075 0.0203 0.0203
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0034 0.0034
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0034 0.0034
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.004 0.0086 0.0086
Brugia malayi hypothetical protein 0.004 0.0086 0.0086
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.011 0.0093
Schistosoma mansoni cpg binding protein 0.003 0.0055 0.005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.1214 0.3958 0.7607
Schistosoma mansoni centrin-related 0.0103 0.0295 0.029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0316 0.0997 0.0982
Brugia malayi G-protein coupled receptor 0.0024 0.0034 0.0034
Brugia malayi nuclear hormone receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0034 0.0034
Plasmodium vivax vivapain-2 0.1214 0.3958 1
Schistosoma mansoni inositol monophosphatase 0.0037 0.0076 0.0071
Loa Loa (eye worm) proteasome subunit beta type 1 0.006 0.0153 0.0153
Echinococcus granulosus caspase 0.0019 0.0017 0.0017
Brugia malayi cathepsin L precursor 0.0301 0.0948 0.0948
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0034 0.0085
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0076 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Echinococcus multilocularis glycoprotein Antigen 5 0.004 0.0086 0.0086
Echinococcus granulosus smad 0.0017 0.0012 0.0012
Onchocerca volvulus 0.0049 0.0118 0.0297
Plasmodium falciparum serine repeat antigen 8 0.0301 0.0948 0.2363
Brugia malayi Pre-SET motif family protein 0.0064 0.0165 0.0165
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0274 0.3447
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.008 0.0848
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0274 0.0274
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0063 0.019
Brugia malayi Blistered cuticle protein 3 0.0066 0.0172 0.0172
Echinococcus multilocularis calpain A 0.1804 0.5903 0.5903
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0459 0.0454
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Trichomonas vaginalis hypothetical protein 0.0341 0.1081 0.2699
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0045 0.0103 0.0103
Schistosoma mansoni peptidylglycine monooxygenase 0.0019 0.0016 0.0011
Toxoplasma gondii troponin c, isotype gamma, putative 0.0103 0.0295 0.0739
Onchocerca volvulus Matrilysin homolog 0.0052 0.0127 0.0321
Loa Loa (eye worm) NCL-1 protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Trichomonas vaginalis calmodulin, putative 0.0112 0.0323 0.0776
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0165 0.041
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0025 0.0025
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1801 0.5894 0.5894
Echinococcus granulosus caspase 2 0.0063 0.0161 0.0161
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0099 0.0099
Trypanosoma brucei calmodulin, putative 0.0103 0.0295 0.0566
Onchocerca volvulus 0.0024 0.0034 0.0085
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0017 0.0036
Schistosoma mansoni cathepsin F (C01 family) 0.1214 0.3958 0.3955
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.008 0.0159
Echinococcus multilocularis tissue type plasminogen activator 0.0064 0.0164 0.0164
Leishmania major protein kinase, putative 0.0103 0.0295 0.0537
Entamoeba histolytica cysteine proteinase 1, putative 0.0678 0.219 0.5515
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0165 0.016
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0091 0.0189
Entamoeba histolytica calcium-binding protein, putative 0.0103 0.0295 0.0707
Onchocerca volvulus 0.0024 0.0033 0.0082
Trypanosoma cruzi small myristoylated protein 1-1 0.0373 0.1185 0.117
Loa Loa (eye worm) RING finger protein nhl-1 0.0019 0.0016 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0025 0.0025
Brugia malayi Proteasome A-type and B-type family protein 0.0079 0.0215 0.0214
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0103 0.0295 0.0705
Loa Loa (eye worm) GABA receptor subunit 0.0041 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0674 0.2179 0.4172
Echinococcus granulosus tissue type plasminogen activator 0.0064 0.0164 0.0164
Schistosoma mansoni brat protein 0.0019 0.0016 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Leishmania major META domain containing protein 0.0216 0.0668 0.1256
Schistosoma mansoni smad 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0341 0.1081 0.1081
Trypanosoma cruzi centrin, putative 0.0112 0.0323 0.0306
Brugia malayi calpain 7 0.0773 0.2505 0.2505
Onchocerca volvulus 0.0066 0.0172 0.0434
Echinococcus granulosus calumenin 0.0106 0.0304 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0065 0.017 0.0165
Schistosoma mansoni acetylcholine receptor-related 0.0035 0.0069 0.0065
Brugia malayi beta-lactamase family protein 0.0038 0.008 0.0079
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0377 0.1197 0.1197
Echinococcus granulosus cpg binding protein 0.0032 0.006 0.006
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0075 0.0203 0.0199
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0025 0.0025
Leishmania major calcineurin B subunit, putative 0.0103 0.0295 0.0537
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0245 0.0763 1
Echinococcus multilocularis laminin 0.0014 0.0003 0.0003
Echinococcus multilocularis musashi 0.0028 0.0048 0.0048
Echinococcus multilocularis calmodulin 0.0103 0.0295 0.0295
Brugia malayi Papain family cysteine protease containing protein 0.0301 0.0948 0.0948
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0035 0.0069 0.0069
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0377 0.1197 0.1196
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0065 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Leishmania major small myristoylated protein-3, putative 0.0316 0.0997 0.1891
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1214 0.3958 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.0034 0.0034
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0042 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Echinococcus multilocularis caspase 8 0.0019 0.0017 0.0017
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.022 0.0682 0.8914
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Trichomonas vaginalis conserved hypothetical protein 0.0301 0.0948 0.2363
Loa Loa (eye worm) calmodulin-like protein 0.0103 0.0295 0.0295
Echinococcus multilocularis dna polymerase eta 0.0047 0.011 0.011
Echinococcus granulosus fmrfamide receptor 0.0024 0.0034 0.0034
Echinococcus granulosus nAChR subunit 0.0041 0.0089 0.0089
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0216 0.0668 0.1283
Onchocerca volvulus 0.0925 0.3004 0.759
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0025 0.0025
Echinococcus multilocularis smad 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Onchocerca volvulus 0.1214 0.3958 1
Echinococcus multilocularis hypothetical protein 0.0773 0.2505 0.2505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0075 0.0203 0.0203
Brugia malayi fibroinase precursor 0.0301 0.0948 0.0948
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Brugia malayi hypothetical protein 0.0035 0.0069 0.0069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0025 0.0025
Brugia malayi Kringle domain containing protein 0.0064 0.0164 0.0164
Giardia lamblia Proteasome subunit beta type 1 0.006 0.0153 0.0365
Onchocerca volvulus 0.0024 0.0034 0.0085
Leishmania major hypothetical protein, conserved 0.0064 0.0164 0.0285
Schistosoma mansoni neuronal calcium sensor 0.0103 0.0295 0.029
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.1674 0.5475 0.5467
Leishmania major prefoldin subunit, putative 0.0063 0.0163 0.0282
Onchocerca volvulus 0.0024 0.0034 0.0085
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0106 0.0304 0.0287
Brugia malayi Papain family cysteine protease containing protein 0.0678 0.219 0.219
Brugia malayi hypothetical protein 0.0017 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0708 0.2289 0.2276
Loa Loa (eye worm) calpain family protein 1 0.1266 0.413 0.413
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0075 0.0203 0.0203
Trypanosoma brucei calpain, putative 0.0615 0.1984 0.3816
Leishmania major hypothetical protein, unknown function 0.0341 0.1081 0.2053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0076 0.015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.295
Loa Loa (eye worm) hypothetical protein 0.0053 0.013 0.013
Onchocerca volvulus 0.0024 0.0034 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0065 0.0124
Brugia malayi Dopamine receptor protein 2 0.0024 0.0034 0.0034
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0034 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.1214 0.3958 1
Echinococcus granulosus tripartite motif containing protein 3 0.0019 0.0016 0.0016
Schistosoma mansoni biogenic amine receptor 0.0024 0.0034 0.0029
Echinococcus granulosus glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0025 0.0025
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Giardia lamblia Cathepsin B precursor 0.0301 0.0948 0.2498
Echinococcus granulosus cathepsin b 0.3046 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0034 0.0029
Onchocerca volvulus 0.0038 0.008 0.02
Plasmodium vivax centrin-1, putative 0.0103 0.0295 0.0734
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Brugia malayi Cathepsin L-like precursor 0.0837 0.2716 0.2716
Echinococcus multilocularis sodium channel protein 0.0037 0.0076 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0034 0.0034
Trypanosoma brucei Calpain-like protein 1.1 0.0912 0.2962 0.5697
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0034 0.0029
Brugia malayi hypothetical protein 0.0026 0.0042 0.0042
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0034 0.0034
Onchocerca volvulus Cathepsin L homolog 0.0301 0.0948 0.2395
Schistosoma mansoni amine GPCR 0.0024 0.0034 0.0029
Brugia malayi hypothetical protein 0.0035 0.0069 0.0069
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0689 0.2228 0.4267
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0075 0.0203 0.0203
Loa Loa (eye worm) matrixin family protein 0.0057 0.0143 0.0143
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0301 0.0948 0.2498
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0165 0.0165
Schistosoma mansoni cathepsin S (C01 family) 0.0301 0.0948 0.0944
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0025 0.0021
Onchocerca volvulus 0.004 0.0086 0.0217
Brugia malayi hypothetical protein 0.0044 0.0099 0.0099
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.017 0.0169
Schistosoma mansoni hypothetical protein 0.0019 0.0016 0.0011
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0022 0.0009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0153 0.0461 0.0461
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0025 0.0021
Giardia lamblia Hypothetical protein 0.0063 0.0163 0.0394
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Onchocerca volvulus Peroxidase homolog 0.0066 0.0172 0.0434
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Brugia malayi Calcium binding EGF domain containing protein 0.0014 0.0003 0.0002
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0017 0.0036
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0678 0.219 0.2186
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0301 0.0948 0.0944
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0079 0.0215 0.2311
Loa Loa (eye worm) hypothetical protein 0.0237 0.0735 0.0735
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0245 0.0763 1
Trypanosoma brucei kinesin, putative 0.0432 0.1379 0.2652
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0061
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0064 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0034 0.0034
Trypanosoma brucei calpain-like protein, putative 0.0773 0.2505 0.4818
Trichomonas vaginalis calcium binding protein, putative 0.0103 0.0295 0.0705
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0024 0.0034 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0034 0.0034
Onchocerca volvulus 0.0038 0.008 0.02
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0301 0.0948 0.2363
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0301 0.0948 0.2365
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0074
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.008 0.0075
Brugia malayi Cell death protein 3 precursor 0.0063 0.0161 0.0161
Trypanosoma brucei mitochondrial calcium uptake 1 0.0103 0.0295 0.0566
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1213 0.3956 0.3946
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0065 0.0093
Schistosoma mansoni cathepsin C 0.0301 0.0948 0.0944
Onchocerca volvulus 0.004 0.0086 0.0217
Giardia lamblia Cysteine protease 0.0301 0.0948 0.2498
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni neurotransmitter gated ion channel 0.0035 0.0069 0.0065
Loa Loa (eye worm) LGC-31 protein 0.0075 0.0203 0.0203
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0076 0.015
Mycobacterium ulcerans hydrolase 0.0029 0.005 0.1449
Brugia malayi ecdysteroid receptor 0.0021 0.0025 0.0025
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0421 0.042
Loa Loa (eye worm) animal heme peroxidase 0.0066 0.0172 0.0172
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0034 0.0034
Trypanosoma brucei prefoldin subunit, putative 0.0063 0.0163 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0558 0.1794 0.3429
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni caspase-7 (C14 family) 0.0063 0.0161 0.0157
Brugia malayi Animal haem peroxidase family protein 0.0066 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Schistosoma mansoni cpg binding protein 0.0032 0.006 0.0056
Brugia malayi Trypsin family protein 0.004 0.0086 0.0086
Leishmania major DNA polymerase kappa, putative 0.002 0.0022 0.0009
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0301 0.0948 0.2387
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0668 0.0652
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1214 0.3958 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0301 0.0948 0.2387
Leishmania major centrin, putative,caltractin, putative 0.0103 0.0295 0.0537
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3046 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.111 0.1095
Plasmodium vivax proteasome subunit beta type-1, putative 0.006 0.0153 0.0374
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0005
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0859 0.165
Loa Loa (eye worm) calpain family protein 1 0.1698 0.5554 0.5554
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Loa Loa (eye worm) transcription factor SMAD2 0.0256 0.0798 0.0798
Trichomonas vaginalis calmodulin-2, putative 0.0103 0.0295 0.0705
Echinococcus multilocularis brain tumor protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Echinococcus granulosus g protein coupled receptor 0.0024 0.0034 0.0034
Echinococcus multilocularis GPCR, family 2 0.0017 0.001 0.001
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0075 0.0203 0.0199
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0076 0.0076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0075 0.0203 0.0203
Schistosoma mansoni neurotransmitter gated ion channel 0.0035 0.0069 0.0065
Brugia malayi calcium-binding protein 0.0103 0.0295 0.0295
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0103 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Toxoplasma gondii EFHC1, putative 0.0103 0.0295 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0025 0.0025
Giardia lamblia Cathepsin L-like protease 0.0301 0.0948 0.2498
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0079 0.0215 0.0198
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Giardia lamblia Cathepsin B precursor 0.0301 0.0948 0.2498
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0065 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Schistosoma mansoni hypothetical protein 0.0017 0.001 0.0006
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0103 0.0295 0.0278
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Onchocerca volvulus 0.0024 0.0034 0.0085
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0065 0.0659
Echinococcus multilocularis geminin 0.0537 0.1724 0.1724
Echinococcus multilocularis proteasome (prosome, macropain) 0.0079 0.0215 0.0215
Schistosoma mansoni calpain-7 (C02 family) 0.0773 0.2505 0.2501
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Onchocerca volvulus 0.1214 0.3958 1
Leishmania major hypothetical protein, conserved 0.035 0.111 0.211
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0005 0.0005
Trypanosoma cruzi conserved protein 0.0567 0.1824 0.181
Plasmodium falciparum glutathione reductase 0.0033 0.0065 0.0123
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0678 0.219 0.2186
Echinococcus multilocularis tar DNA binding protein 0.0065 0.017 0.017
Echinococcus multilocularis caspase 0.0019 0.0017 0.0017
Toxoplasma gondii cathepsin CPC1 0.0301 0.0948 0.2391
Trypanosoma brucei hypothetical protein 0.0615 0.1984 0.3816
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0079 0.0215 0.0215
Onchocerca volvulus 0.1214 0.3958 1
Trypanosoma brucei calpain-like protein, putative 0.0773 0.2505 0.4818
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0076 0.0144
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0034 0.0034
Entamoeba histolytica hypothetical protein, conserved 0.0106 0.0304 0.073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Brugia malayi Matrixin family protein 0.0024 0.0033 0.0032
Echinococcus multilocularis cysteine protease 0.1214 0.3958 0.3958
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0025 0.0025
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0076 0.0076
Plasmodium falciparum serine repeat antigen 4 0.0301 0.0948 0.2363
Echinococcus granulosus lamin 0.0028 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Toxoplasma gondii hypothetical protein 0.0341 0.1081 0.2725
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) acetylcholine receptor protein 0.0035 0.0069 0.0069
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0342 0.1082 0.2081
Brugia malayi hypothetical protein 0.0066 0.0172 0.0172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0025 0.0025
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0075 0.0203 0.0203
Loa Loa (eye worm) fibroinase 0.1214 0.3958 0.3958
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0042 0.0025
Trypanosoma brucei hypothetical protein, conserved 0.0103 0.0295 0.0566
Entamoeba histolytica grainin 2 0.0112 0.0323 0.0778
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0103 0.0219
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1047 0.3409 0.6557
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Loa Loa (eye worm) hypothetical protein 0.0043 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0033
Schistosoma mansoni lamin 0.0028 0.0048 0.0044
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0065 0.0093
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0301 0.0948 0.2363
Brugia malayi calpain 5 0.0432 0.1379 0.1379
Entamoeba histolytica grainin, putative 0.0106 0.0304 0.073
Brugia malayi excitatory GABA receptor EXP-1A 0.0075 0.0203 0.0203
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0034 0.0034
Onchocerca volvulus 0.0024 0.0034 0.0085
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.002 0.0007
Plasmodium falciparum serine repeat antigen 6 0.0301 0.0948 0.2363
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0301 0.0948 0.2363
Toxoplasma gondii ABC1 family protein 0.0038 0.008 0.0194
Toxoplasma gondii microneme protein MIC17B 0.003 0.0053 0.0127
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0025 0.0063
Onchocerca volvulus Cell death protein 3 homolog 0.0063 0.0161 0.0407
Onchocerca volvulus 0.0075 0.0203 0.0513
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.1214 0.3958 0.3948
Plasmodium vivax vivapain-3 0.0678 0.219 0.5528
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0076 0.0152
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0048 0.0048
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0019 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Brugia malayi EF hand family protein 0.0106 0.0304 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0065 0.017 0.0165
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0859 0.165
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0711 0.2298 0.2298
Schistosoma mansoni calpain C (C02 family) 0.0773 0.2505 0.2501
Loa Loa (eye worm) hypothetical protein 0.0063 0.0163 0.0163
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0301 0.0948 0.0944
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.008 0.0063
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0155 0.0155
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0103 0.0254
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0075 0.0203 0.0203
Schistosoma mansoni peroxidasin 0.0066 0.0172 0.0167
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Brugia malayi follicle stimulating hormone receptor 0.0024 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0431 0.1377 0.1373
Plasmodium vivax prefoldin subunit 6, putative 0.0063 0.0163 0.04
Echinococcus granulosus enteropeptidase 0.004 0.0086 0.0086
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0022 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Brugia malayi Matrixin family protein 0.0024 0.0033 0.0032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1047 0.3409 0.6547
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0041 0.0089 0.0088
Giardia lamblia Hypothetical protein 0.0301 0.0948 0.2498
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Echinococcus granulosus brain tumor protein 0.0019 0.0016 0.0016
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.006 0.0153 0.0136
Schistosoma mansoni neuropeptide receptor 0.0024 0.0034 0.0029
Loa Loa (eye worm) animal heme peroxidase 0.0066 0.0172 0.0172
Echinococcus granulosus caspase 8 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.004 0.0086 0.0086
Onchocerca volvulus 0.0044 0.0099 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0025 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.022 0.0682 0.8914
Echinococcus multilocularis transmembrane protease serine 3 0.004 0.0086 0.0086
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0165 0.0165
Entamoeba histolytica proteasome subunit beta type 1, putative 0.006 0.0153 0.0346
Trypanosoma cruzi cysteine peptidase, putative 0.159 0.5198 0.519
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Plasmodium vivax unspecified product 0.0678 0.219 0.5528
Entamoeba histolytica cysteine proteinase, putative 0.1214 0.3958 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0093
Echinococcus granulosus g protein coupled receptor 0.0024 0.0034 0.0034
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0035 0.0069 0.0069
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.017 0.017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0558 0.1794 0.178
Brugia malayi Animal haem peroxidase family protein 0.0066 0.0172 0.0172
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0044 0.0099 0.0094
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0091 0.0187
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.1357 0.4429 0.4429
Onchocerca volvulus 0.0028 0.0048 0.0121
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0069 0.0069
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0912 0.2962 0.295
Loa Loa (eye worm) hypothetical protein 0.3046 1 1
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.1283
Schistosoma mansoni calmodulin 0.0103 0.0295 0.029
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0034 0.0034
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.005 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0301 0.0948 0.2363
Plasmodium vivax unspecified product 0.0377 0.1197 0.3015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0042 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0005 0.0004
Entamoeba histolytica hypothetical protein 0.0301 0.0948 0.2365
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0377 0.1199 0.1199
Schistosoma mansoni Mername-AA248 (C02 family) 0.0773 0.2505 0.2501
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.004 0.0086 0.0086
Brugia malayi proteasome subunit beta type 1 0.006 0.0153 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.159 0.5198 0.519
Leishmania major centrin, putative 0.0103 0.0295 0.0537
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3046 1 1
Schistosoma mansoni neuropeptide receptor 0.0024 0.0034 0.0029
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0034 0.0034
Trypanosoma cruzi cysteine protease, putative 0.0678 0.219 0.2177
Brugia malayi Animal haem peroxidase family protein 0.0066 0.0172 0.0172
Brugia malayi cathepsin Z-like cysteine proteinase 0.0301 0.0948 0.0948
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0421 0.0421
Loa Loa (eye worm) calpain 5 0.0432 0.1379 0.1379
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0082
Onchocerca volvulus 0.003 0.0053 0.0133
Onchocerca volvulus 0.0103 0.0295 0.0744
Leishmania major hypothetical protein, conserved 0.0567 0.1824 0.3488
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0075 0.0203 0.0203
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.008 0.0848
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0034 0.0034
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0065 0.2264
Echinococcus multilocularis tripartite motif containing protein 3 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0271 0.085 0.085
Giardia lamblia Hypothetical protein 0.0106 0.0304 0.0771
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0103 0.0295 0.0705
Trichomonas vaginalis calcium binding protein, putative 0.0112 0.0323 0.0776
Schistosoma mansoni neurotransmitter gated ion channel 0.0041 0.0089 0.0084
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0558 0.1794 0.178
Trypanosoma brucei centrin, putative 0.0103 0.0295 0.0566
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0192 0.0586 0.0586
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0029 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0316 0.0997 0.1916
Mycobacterium ulcerans lipase LipD 0.0038 0.008 0.2999
Leishmania major cathepsin L-like protease 0.1214 0.3958 0.7607
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Leishmania major DNA polymerase eta, putative 0.0033 0.0064 0.009
Toxoplasma gondii centrin 0.0103 0.0295 0.0739
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0012 0.0012
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Echinococcus multilocularis calpain 0.0773 0.2505 0.2505
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0012 0.0012
Trypanosoma cruzi cruzipain precursor, putative 0.1674 0.5475 0.5467
Loa Loa (eye worm) animal heme peroxidase 0.0066 0.0172 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0421 0.0416
Trichomonas vaginalis calpain, putative 0.0341 0.1081 0.2699
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni mitochondrial solute carrier 0.0103 0.0295 0.029
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.5683
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Trichomonas vaginalis centrin, putative 0.0103 0.0295 0.0705
Trypanosoma cruzi cysteine peptidase, putative 0.0678 0.219 0.2177
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0186 0.0568 0.0568
Loa Loa (eye worm) RNA binding protein 0.0065 0.017 0.017
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0035 0.0069 0.0069
Brugia malayi Matrixin family protein 0.0024 0.0033 0.0032
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0341 0.1081 0.2725
Echinococcus granulosus orexin receptor type 2 0.0024 0.0034 0.0034
Onchocerca volvulus 0.003 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0041 0.0089 0.0223
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0075 0.0203 0.0203
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0075 0.0203 0.0203
Schistosoma mansoni biogenic amine receptor 0.0024 0.0034 0.0029
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Echinococcus multilocularis lamin dm0 0.0028 0.0048 0.0048
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Schistosoma mansoni hypothetical protein 0.0019 0.0016 0.0011
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0048 0.0048
Leishmania major proteasome beta 5 subunit, putative 0.0079 0.0215 0.0381
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Trypanosoma brucei Calpain-like protein CALP1.3 0.0558 0.1794 0.3449
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0065 0.0065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Loa Loa (eye worm) AStacin protease 0.0028 0.0047 0.0047
Trypanosoma brucei centrin, putative 0.0103 0.0295 0.0566
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Plasmodium vivax unspecified product 0.0301 0.0948 0.2387
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0075 0.0203 0.0199
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0075 0.0203 0.0199
Entamoeba histolytica cysteine proteinase 2 0.0678 0.219 0.5515
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0053 0.0053
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Brugia malayi nuclear receptor NHR-88 0.0021 0.0025 0.0025
Toxoplasma gondii EF hand domain-containing protein 0.0103 0.0295 0.0739
Trichomonas vaginalis set domain proteins, putative 0.0501 0.1606 0.4031
Echinococcus granulosus peroxidasin 0.0066 0.0172 0.0172
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Echinococcus granulosus bloom syndrome protein 0.0022 0.0029 0.0029
Schistosoma mansoni myosin xvIII 0.0024 0.0034 0.0029
Loa Loa (eye worm) blistered cuticle protein 3 0.0066 0.0172 0.0172
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Schistosoma mansoni reticulocalbin 0.0106 0.0304 0.0299
Onchocerca volvulus 0.0021 0.0025 0.0063
Onchocerca volvulus 0.0075 0.0203 0.0513
Leishmania major hypothetical protein, conserved 0.0038 0.008 0.0121
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0065 0.5
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.011
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0034 0.0034
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0022 0.0012
Echinococcus granulosus laminin 0.0014 0.0003 0.0003
Brugia malayi Uncoordinated protein 44 0.0015 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.115 0.3748 0.9467
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0301 0.0948 0.2498
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0041 0.0089 0.0084
Plasmodium falciparum prefoldin subunit 6, putative 0.0063 0.0163 0.0371
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.008 0.008
Brugia malayi Trypsin family protein 0.004 0.0086 0.0086
Entamoeba histolytica cysteine proteinase, putative 0.0837 0.2716 0.685
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.006 0.0153 0.0262
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0558 0.1794 0.178
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0041 0.0089 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Loa Loa (eye worm) programmed cell death protein 6 0.0106 0.0304 0.0304
Echinococcus granulosus GPCR family 2 0.0017 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trichomonas vaginalis calpain, putative 0.0341 0.1081 0.2699
Loa Loa (eye worm) EF hand family protein 0.0103 0.0295 0.0295
Brugia malayi MH2 domain containing protein 0.0256 0.0798 0.0798
Onchocerca volvulus 0.0035 0.0069 0.0175
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0301 0.0948 0.2387
Brugia malayi Dopamine receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.005
Echinococcus multilocularis dna polymerase kappa 0.002 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0034 0.0034
Brugia malayi TAR-binding protein 0.0065 0.017 0.0169
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.022 0.0682 0.8914
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.0391 0.0391
Leishmania major cathepsin L-like protease 0.1214 0.3958 0.7607
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.006 0.0153 0.0136
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.0163 0.0146
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Plasmodium falciparum serine repeat antigen 9 0.0301 0.0948 0.2363
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0075 0.0203 0.0203
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0034 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0065 0.017 0.0165
Onchocerca volvulus 0.003 0.0053 0.0133
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi Trypsin-like protease protein 5 0.004 0.0086 0.0086
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.021 0.021
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0103 0.0295 0.0566
Plasmodium vivax calpain, putative 0.0773 0.2505 0.6324
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0025 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0034 0.0034
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0301 0.0948 0.2387
Onchocerca volvulus 0.003 0.0053 0.0133
Toxoplasma gondii kringle domain-containing protein 0.0064 0.0164 0.0409
Toxoplasma gondii prefoldin subunit 6, putative 0.0063 0.0163 0.0406
Mycobacterium ulcerans hypothetical protein 0.0038 0.008 0.2999
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0034 0.0034
Trypanosoma brucei unspecified product 0.0216 0.0668 0.1283
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0773 0.2505 0.4802
Brugia malayi hypothetical protein 0.0242 0.0754 0.0753
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0034 0.0034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0971 0.3156 0.3145
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0025 0.0025
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0103 0.0295 0.0295
Echinococcus granulosus centrin 2 0.0103 0.0295 0.0295
Brugia malayi cathepsin Z-like cysteine proteinase 0.0301 0.0948 0.0948
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Schistosoma mansoni neuropeptide receptor 0.0024 0.0034 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Onchocerca volvulus 0.003 0.0053 0.0133
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0678 0.219 0.5514
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0025 0.0063
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1047 0.3409 0.3397
Leishmania major cathepsin L-like protease 0.159 0.5198 1
Echinococcus granulosus calmodulin 0.0103 0.0295 0.0295
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.0754 0.0754
Onchocerca volvulus 0.0038 0.008 0.02
Mycobacterium ulcerans beta-lactamase 0.0038 0.008 0.2999
Plasmodium falciparum cysteine repeat modular protein 1 0.0064 0.0164 0.0374
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0301 0.0948 0.2365
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0012 0.0012
Onchocerca volvulus 0.0075 0.0203 0.0513
Giardia lamblia Cathepsin B precursor 0.0301 0.0948 0.2498
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Schistosoma mansoni inositol monophosphatase 0.0037 0.0076 0.0071
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Onchocerca volvulus 0.0035 0.0069 0.0175
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.011 0.021
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0034 0.0034
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.008 0.008
Echinococcus multilocularis calmodulin 0.0103 0.0295 0.0295
Brugia malayi G-protein coupled receptor 0.0024 0.0034 0.0034
Brugia malayi Papain family cysteine protease containing protein 0.0301 0.0948 0.0948
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0668 0.0652
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3046 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Echinococcus granulosus lamin dm0 0.0028 0.0048 0.0048
Echinococcus granulosus proteasome prosome macropain 0.0079 0.0215 0.0215
Onchocerca volvulus 0.0024 0.0034 0.0085
Onchocerca volvulus 0.0024 0.0034 0.0085
Plasmodium falciparum cysteine proteinase falcipain 3 0.1214 0.3958 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Echinococcus granulosus EF hand domain containing family member A2 0.0103 0.0295 0.0295
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0017 0.0012
Schistosoma mansoni survival motor neuron protein 0.0049 0.0118 0.0113
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0065 0.0124
Onchocerca volvulus Peroxidasin homolog 0.0066 0.0172 0.0434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1081 0.2699
Leishmania major calpain protease-like protein 0.0341 0.1081 0.2053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0082
Onchocerca volvulus 0.1214 0.3958 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Entamoeba histolytica protein kinase, putative 0.0432 0.1379 0.3458
Toxoplasma gondii microneme protein MIC4 0.003 0.0053 0.0127
Brugia malayi Latrophilin receptor protein 2 0.0017 0.001 0.001
Brugia malayi MH2 domain containing protein 0.0017 0.0012 0.0012
Echinococcus granulosus calpain A 0.0773 0.2505 0.2505
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0025 0.0025
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0773 0.2505 0.2492
Echinococcus granulosus cathepsin l1 0.0837 0.2716 0.2716
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0034 0.0029
Echinococcus granulosus proteasome prosome macropain subunit beta 0.006 0.0153 0.0153
Trichomonas vaginalis calcium binding protein, putative 0.0103 0.0295 0.0705
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0164 0.0408
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Trichomonas vaginalis esterase, putative 0.0038 0.008 0.0159
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0029 0.0029
Brugia malayi Thioredoxin reductase 0.0097 0.0274 0.0273
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0034 0.0034
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0165 0.0165
Mycobacterium tuberculosis Conserved protein 0.0038 0.008 0.0848
Leishmania major hypothetical protein, conserved 0.0103 0.0295 0.0537
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0093
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Schistosoma mansoni cathepsin s 0.0377 0.1197 0.1193
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0076 0.0114
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0034 0.0029
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0711 0.2298 0.2295
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1047 0.3409 0.3397
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Trypanosoma brucei small myristoylated protein 1-2 0.0373 0.1185 0.2278
Echinococcus multilocularis fibrillin 1 0.0014 0.0003 0.0003
Brugia malayi Cation transporter family protein 0.0075 0.0203 0.0203
Echinococcus multilocularis sex peptide receptor 0.0024 0.0034 0.0034
Echinococcus multilocularis cysteine protease 0.1214 0.3958 0.3958
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0034 0.0034
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0063 0.063
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0065 0.0065
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0539 0.1732 0.1718
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0076 0.015
Echinococcus multilocularis enteropeptidase 0.004 0.0086 0.0086
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.001 0.001
Schistosoma mansoni hypothetical protein 0.004 0.0086 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.5697
Loa Loa (eye worm) TAR-binding protein 0.0065 0.017 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.0164 0.0148
Echinococcus granulosus glycine receptor subunit beta 0.0075 0.0203 0.0203
Loa Loa (eye worm) MH2 domain-containing protein 0.0256 0.0798 0.0798
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0091 0.02
Schistosoma mansoni hypothetical protein 0.0024 0.0034 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0153 0.0461 0.0457
Loa Loa (eye worm) calpain 0.0773 0.2505 0.2505
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0014 0.0003 0.0003
Onchocerca volvulus 0.003 0.0053 0.0133
Echinococcus multilocularis EF hand domain containing family member A2 0.0106 0.0304 0.0304
Schistosoma mansoni cathepsin B (C01 family) 0.0301 0.0948 0.0944
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.008 0.0848
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0301 0.0948 0.2363
Trypanosoma cruzi cysteine proteinase, putative 0.0678 0.219 0.2177
Plasmodium falciparum proteasome subunit beta type-5 0.0079 0.0215 0.0501
Onchocerca volvulus 0.0066 0.0172 0.0434
Echinococcus granulosus transmembrane protease serine 3 0.004 0.0086 0.0086
Toxoplasma gondii microneme protein MIC17C 0.003 0.0053 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Giardia lamblia Cathepsin B precursor 0.115 0.3748 1
Schistosoma mansoni hypothetical protein 0.0036 0.0074 0.007
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0017 0.0036
Loa Loa (eye worm) ctsf protein 0.1214 0.3958 0.3958
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0022 0.004
Echinococcus multilocularis glycine receptor subunit beta 0.0075 0.0203 0.0203
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0025 0.0021
Plasmodium falciparum serine repeat antigen 2 0.0301 0.0948 0.2363
Brugia malayi hypothetical protein 0.0128 0.0376 0.0376
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0678 0.219 0.4212
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0075 0.0203 0.0203
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0103 0.0295 0.0278
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0103 0.0254
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0042 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0022 0.0005
Onchocerca volvulus 0.003 0.0053 0.0133
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0041 0.0089 0.0088
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0041 0.0089 0.0088
Schistosoma mansoni calpain (C02 family) 0.0773 0.2505 0.2501
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.013 0.0129
Plasmodium falciparum thioredoxin reductase 0.0033 0.0065 0.0123
Loa Loa (eye worm) hypothetical protein 0.0028 0.0048 0.0048
Trypanosoma cruzi major cysteine proteinase, putative 0.0677 0.2188 0.2175
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0837 0.2716 0.2716
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.008 0.0159
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0075 0.0203 0.0203
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.008 0.0848
Treponema pallidum NADH oxidase 0.0033 0.0065 0.5
Giardia lamblia Cysteine protease 0.0301 0.0948 0.2498
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.0652
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0034 0.0029
Trypanosoma brucei conserved protein 0.0225 0.0699 0.1342
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0034 0.0034
Brugia malayi hypothetical protein 0.0035 0.0069 0.0069
Entamoeba histolytica calcium binding family protein 0.0103 0.0295 0.0707
Schistosoma mansoni histamine h1 receptor 0.0024 0.0034 0.0029
Brugia malayi Cation transporter family protein 0.0075 0.0203 0.0203
Schistosoma mansoni amine GPCR 0.0024 0.0034 0.0029
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0025 0.0021
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0103 0.0248
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0034 0.0034
Brugia malayi Pre-SET motif family protein 0.044 0.1406 0.1405
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0034 0.0034
Onchocerca volvulus Matrilysin homolog 0.0024 0.0033 0.0082
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0042 0.0079
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0421 0.0416
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Leishmania major receptor-type adenylate cyclase a-like protein 0.0216 0.0668 0.1256
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0045 0.0103 0.0098
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0034 0.0034
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0029 0.005 0.0448
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Toxoplasma gondii thioredoxin reductase 0.0097 0.0274 0.0685
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0301 0.0948 0.0944
Echinococcus granulosus cathepsin L cysteine protease 0.0678 0.219 0.219
Brugia malayi beta-lactamase 0.0038 0.008 0.0079
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.1377 0.1377
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0118 0.0118
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Trichomonas vaginalis calcium binding protein, putative 0.0103 0.0295 0.0705
Onchocerca volvulus Cathepsin L homolog 0.1214 0.3958 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Brugia malayi hypothetical protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0075 0.0203 0.0203
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0008
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0711 0.2298 0.2298
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.013 0.013
Schistosoma mansoni cathepsin F (C01 family) 0.1214 0.3958 0.3955
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0053 0.0127
Trypanosoma cruzi kinesin, putative 0.0432 0.1379 0.1365
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0301 0.0948 0.0944
Onchocerca volvulus 0.0024 0.0034 0.0085
Trypanosoma brucei I/6 autoantigen 0.0103 0.0295 0.0566
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0216 0.0668 0.1256
Brugia malayi Inositol-1 0.0037 0.0076 0.0076
Echinococcus granulosus allatostatin A receptor 0.0024 0.0034 0.0034
Brugia malayi glutathione reductase 0.0097 0.0274 0.0273
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3046 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0075 0.0203 0.0203
Brugia malayi G protein-coupled receptor 0.0024 0.0034 0.0034
Trypanosoma brucei calmodulin, putative 0.0106 0.0304 0.0583
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Plasmodium falciparum serine repeat antigen 7 0.0301 0.0948 0.2363
Entamoeba histolytica prefoldin subunit 6, putative 0.0063 0.0163 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Brugia malayi Smad1 0.0017 0.0012 0.0012
Toxoplasma gondii microneme protein MIC17A 0.003 0.0053 0.0127
Onchocerca volvulus 0.004 0.0086 0.0217
Loa Loa (eye worm) cysteine protease 0.1214 0.3958 0.3958
Echinococcus granulosus programmed cell death protein 0.0112 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma cruzi cysteine proteinase, putative 0.0678 0.219 0.2177
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0034 0.0034
Leishmania major calmodulin, putative 0.0103 0.0295 0.0537
Brugia malayi Papain family cysteine protease containing protein 0.0678 0.219 0.219
Brugia malayi RNA binding protein 0.0065 0.017 0.0169
Loa Loa (eye worm) hypothetical protein 0.0064 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Echinococcus granulosus calcium uptake protein 1 0.0106 0.0304 0.0304
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0034 0.0034
Echinococcus granulosus tar DNA binding protein 0.0065 0.017 0.017
Toxoplasma gondii proteasome subunit beta type, putative 0.0079 0.0215 0.0536
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0558 0.1794 0.178
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Brugia malayi RE15519p 0.0024 0.0034 0.0034
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0022 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Schistosoma mansoni hypothetical protein 0.0537 0.1724 0.1721
Mycobacterium tuberculosis Probable reductase 0.022 0.0682 0.8914
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.115 0.3748 0.7201
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Schistosoma mansoni coup transcription factor 0.0021 0.0025 0.0021
Schistosoma mansoni intermediate filament proteins 0.0028 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Onchocerca volvulus 0.003 0.0053 0.0133
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0805 0.2609 0.5003
Trypanosoma cruzi centrin-3 0.0112 0.0323 0.0306
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi Cation transporter family protein 0.0075 0.0203 0.0203
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0075 0.0203 0.0203
Brugia malayi Protein kinase domain containing protein 0.0064 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0025 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0025 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0301 0.0948 0.0944
Echinococcus multilocularis Smad4 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Echinococcus multilocularis cathepsin b 0.3046 1 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0445 0.0445
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0042 0.01
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.003 0.0053 0.0127
Toxoplasma gondii centrin, putative 0.0103 0.0295 0.0739
Onchocerca volvulus 0.0024 0.0034 0.0085
Loa Loa (eye worm) B-box zinc finger family protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0711 0.2298 0.2298
Brugia malayi B-box zinc finger family protein 0.0019 0.0016 0.0016
Onchocerca volvulus 0.004 0.0086 0.0217
Onchocerca volvulus 0.0501 0.1606 0.4057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0025 0.0025
Echinococcus granulosus EF HAND 1 calcium binding site 0.0103 0.0295 0.0295
Echinococcus granulosus calpain 7 C02 family 0.0773 0.2505 0.2505
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0539 0.1732 0.331
Trypanosoma brucei Calpain-like protein 1.2 0.0708 0.2289 0.4403
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1793 0.5869 0.5869
Giardia lamblia Cathepsin B precursor 0.0301 0.0948 0.2498
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Brugia malayi Serotonin receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0064 0.0155
Loa Loa (eye worm) glutathione reductase 0.0097 0.0274 0.0274
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.0163 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Echinococcus granulosus Tolloid protein 1 0.0045 0.0103 0.0103
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0025 0.0025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0971 0.3156 0.3145
Toxoplasma gondii hypothetical protein 0.003 0.0053 0.0127
Giardia lamblia Encystation-specific protease 0.0301 0.0948 0.2498
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.159 0.5198 0.519
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0301 0.0948 0.0944
Loa Loa (eye worm) hypothetical protein 0.0837 0.2716 0.2716
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0086 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0044 0.0099 0.0099
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0034 0.0034
Brugia malayi programmed cell death protein 6 0.0103 0.0295 0.0295
Toxoplasma gondii microneme protein, putative 0.003 0.0053 0.0127
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1214 0.3958 0.3958
Schistosoma mansoni tar DNA-binding protein 0.0065 0.017 0.0165
Schistosoma mansoni calmodulin related calcium binding protein 0.0103 0.0295 0.029
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.0751 0.9839
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Schistosoma mansoni amine GPCR 0.0024 0.0034 0.0029
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0082
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0867 0.2812 0.5396
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0025 0.0021
Loa Loa (eye worm) animal heme peroxidase 0.0066 0.0172 0.0172
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0034 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0079 0.0215 0.021
Echinococcus granulosus dnaJ subfamily B 0.0431 0.1377 0.1377
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0034 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0034 0.0034
Echinococcus multilocularis cpg binding protein 0.0032 0.006 0.006
Trypanosoma cruzi caltractin, putative 0.0103 0.0295 0.0278
Onchocerca volvulus 0.0075 0.0203 0.0513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0678 0.219 0.5514
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0103 0.0295 0.0734
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0301 0.0948 0.0944
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0022 0.004
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0034 0.0034
Brugia malayi Fibulin-1 precursor 0.0014 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0103 0.0295 0.0295
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0421 0.0421
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0588 0.1894 0.188
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0022 0.0022
Echinococcus granulosus Mastin 0.004 0.0086 0.0086
Loa Loa (eye worm) beta-lactamase 0.0038 0.008 0.008
Leishmania major cathepsin L-like protease 0.159 0.5198 1
Echinococcus granulosus cathepsin L 0.0678 0.219 0.219
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Echinococcus multilocularis Mastin 0.004 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Onchocerca volvulus Cathepsin L homolog 0.1214 0.3958 1
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0421 0.0421
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0075 0.0203 0.0203
Plasmodium falciparum calpain 0.0341 0.1081 0.2699
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.006 0.0153 0.0153
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0076 0.2811
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0034 0.0034
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0245 0.0763 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0017 0.0012
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Echinococcus granulosus cathepsin l1 0.1214 0.3958 0.3958
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Brugia malayi calpain 5 0.0341 0.1081 0.108
Trypanosoma cruzi kinesin, putative 0.0432 0.1379 0.1365
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Echinococcus granulosus prefoldin subunit 6 0.0063 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0079 0.0215 0.0501
Trypanosoma brucei Metacaspase-4 0.0019 0.0017 0.0031
Echinococcus multilocularis prefoldin subunit 6 0.0063 0.0163 0.0163
Onchocerca volvulus 0.0024 0.0034 0.0085
Schistosoma mansoni thyroid hormone receptor 0.0153 0.0461 0.0457
Echinococcus multilocularis glycine receptor subunit beta 0.0075 0.0203 0.0203
Echinococcus granulosus neurocalcin 0.0103 0.0295 0.0295
Echinococcus multilocularis programmed cell death protein 0.0112 0.0323 0.0323
Trypanosoma brucei Calpain-like protein 2 0.0689 0.2228 0.4285
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0025 0.0025
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Trypanosoma brucei metacaspase MCA2 0.0019 0.0017 0.0031
Schistosoma mansoni calpain-2 (C02 family) 0.0341 0.1081 0.1076
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0295 0.0705
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.008 0.0848
Schistosoma mansoni hypothetical protein 0.0054 0.0134 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0022 0.0014
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0034 0.0029
Brugia malayi hypothetical protein 0.0035 0.0069 0.0069
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.008 0.2999
Onchocerca volvulus 0.1214 0.3958 1
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0163 0.0371
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0033
Trypanosoma cruzi calmodulin, putative 0.0103 0.0295 0.0278
Brugia malayi Animal haem peroxidase family protein 0.0066 0.0172 0.0172
Echinococcus multilocularis peroxidasin 0.0066 0.0172 0.0172
Trypanosoma brucei centrin-3 0.0112 0.0323 0.0619
Echinococcus multilocularis lamin 0.0028 0.0048 0.0048
Leishmania major small myristoylated protein-2 0.068 0.2196 0.4206
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0065 0.0061
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis calbindin 32 0.0106 0.0304 0.0304
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0301 0.0948 0.2387
Loa Loa (eye worm) ACC-1 protein 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0668 0.0652
Schistosoma mansoni calpain-7 (C02 family) 0.0773 0.2505 0.2501
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0459 0.0459
Brugia malayi neuropeptide F receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0103 0.0295 0.0278
Trypanosoma cruzi calmodulin, putative 0.0103 0.0295 0.0278
Schistosoma mansoni hypothetical protein 0.0019 0.0016 0.0011
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0065 0.0132
Brugia malayi Trypsin family protein 0.004 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0558 0.1794 0.3429
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0022 0.0017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.001 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0034 0.0034
Schistosoma mansoni nAChR subunit 0.0035 0.0069 0.0065
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0034 0.0029
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0034 0.0029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0708 0.2289 0.2276
Echinococcus granulosus g protein coupled receptor 0.0024 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0537 0.1724 0.1721
Echinococcus granulosus somatostatin receptor 0.0024 0.0034 0.0034
Brugia malayi intermediate filament protein 0.0028 0.0048 0.0048
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0065 0.0124
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1214 0.3958 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi GnHR receptor homolog 0.0024 0.0034 0.0034
Plasmodium falciparum serine repeat antigen 1 0.0301 0.0948 0.2363
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1047 0.3409 0.6547
Brugia malayi EF hand family protein 0.0103 0.0295 0.0295
Trypanosoma cruzi I/6 autoantigen, putative 0.0103 0.0295 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0301 0.0948 0.2363
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1801 0.5894 0.5894
Schistosoma mansoni hypothetical protein 0.004 0.0086 0.0082
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0017 0.0012
Loa Loa (eye worm) inositol-1 0.0037 0.0076 0.0076
Schistosoma mansoni biogenic amine receptor 0.0024 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.1794 0.178
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0034 0.0029
Schistosoma mansoni hypothetical protein 0.0049 0.0118 0.0113
Onchocerca volvulus 0.0024 0.0034 0.0085
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.004 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Echinococcus granulosus neuronal calcium sensor 0.0103 0.0295 0.0295
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0301 0.0948 0.0948
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0539 0.1732 0.3331
Loa Loa (eye worm) hypothetical protein 0.0242 0.0754 0.0754
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma cruzi unspecified product 0.0373 0.1185 0.117
Leishmania major calmodulin-like protein 0.0103 0.0295 0.0537
Onchocerca volvulus Dual oxidase homolog 0.0066 0.0172 0.0434
Loa Loa (eye worm) matrixin family protein 0.0052 0.0127 0.0127
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.008 0.008
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0034 0.0029
Giardia lamblia DINP protein human, muc B family 0.002 0.0022 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.5683
Onchocerca volvulus 0.0024 0.0034 0.0085
Echinococcus granulosus death domain containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.008 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0025 0.0025
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0079 0.0215 0.2656
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Onchocerca volvulus 0.0075 0.0203 0.0513
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0615 0.1984 0.3816
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Trypanosoma cruzi cruzipain precursor, putative 0.159 0.5198 0.519
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.057 0.1836 0.1822
Brugia malayi ORL1-like opioid receptor 0.0024 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Toxoplasma gondii preprocathepsin c precursor, putative 0.0301 0.0948 0.2391
Brugia malayi Cathepsin L-like precursor 0.0377 0.1197 0.1196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Schistosoma mansoni adenoreceptor 0.0024 0.0034 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0678 0.219 0.5515
Leishmania major centrin, putative 0.0103 0.0295 0.0537
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0678 0.219 0.2177
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Leishmania major calmodulin-like protein 0.0103 0.0295 0.0537
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0022 0.004
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.035 0.111 0.2134
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0316 0.0997 0.0982
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0048 0.0048
Trypanosoma brucei small myristoylated protein 1-1 0.0373 0.1185 0.2278
Schistosoma mansoni DNA polymerase eta 0.0047 0.011 0.0105
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.008 0.0848
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0025 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0615 0.1984 0.3797
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0106 0.0304 0.0299
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.1283
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0005 0.0005
Echinococcus granulosus cathepsin L 0.0301 0.0948 0.0948
Plasmodium vivax vivapain-1 0.0678 0.219 0.5528
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Onchocerca volvulus 0.0024 0.0034 0.0085
Plasmodium falciparum centrin-1 0.0103 0.0295 0.0705
Schistosoma mansoni neuropeptide receptor 0.0024 0.0034 0.0029
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.115 0.3748 0.3737
Trichomonas vaginalis myosin light chain 1, putative 0.0103 0.0295 0.0705
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0022 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0066 0.0172 0.0172
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0034 0.0034
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0034 0.0034
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0035 0.0069 0.0069
Plasmodium falciparum proteasome subunit beta type-1, putative 0.006 0.0153 0.0344
Echinococcus granulosus sex peptide receptor 0.0024 0.0034 0.0034
Brugia malayi CXXC zinc finger family protein 0.003 0.0055 0.0054
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0773 0.2505 0.2492
Echinococcus granulosus geminin 0.0537 0.1724 0.1724
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0805 0.2609 0.5003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0271 0.085 0.0849
Loa Loa (eye worm) hypothetical protein 0.0837 0.2716 0.2716
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0859 0.165
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0065 0.0153
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0301 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0867 0.2812 0.5396
Giardia lamblia Cathepsin L-like protease 0.0301 0.0948 0.2498
Loa Loa (eye worm) ACC-1 protein 0.0075 0.0203 0.0203
Onchocerca volvulus 0.0064 0.0164 0.0415
Echinococcus granulosus calpain A 0.1804 0.5903 0.5903
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Entamoeba histolytica cysteine protease, putative 0.1214 0.3958 1
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0005 0.0005
Brugia malayi cathepsin L-like precursor 0.0837 0.2716 0.2716
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0274 0.0274
Onchocerca volvulus 0.0028 0.0048 0.0121
Echinococcus granulosus calpain 0.0773 0.2505 0.2505
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0274 0.068
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1801 0.5894 0.5892
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1214 0.3958 1
Toxoplasma gondii subtilisin SUB12 0.003 0.0053 0.0127
Trypanosoma brucei antigen, putative 0.0773 0.2505 0.4818
Echinococcus granulosus cathepsin L cysteine proteinase 0.1214 0.3958 0.3958
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0075 0.0203 0.0203
Echinococcus granulosus cathepsin b 0.3046 1 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0064 0.0164 0.0164
Brugia malayi Melatonin receptor type 1A 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Brugia malayi Hypothetical RING finger protein F54G8.4 in chromosome III 0.0019 0.0016 0.0016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.001 0.001
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0034 0.0034
Giardia lamblia Hypothetical protein 0.0301 0.0948 0.2498
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0025 0.0063
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0025 0.0021
Trypanosoma brucei unspecified product 0.002 0.0022 0.004
Brugia malayi Cathepsin L-like cysteine proteinase 0.0837 0.2716 0.2716
Brugia malayi Protein kinase domain containing protein 0.0015 0.0005 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0025 0.0025
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0103 0.0295 0.0278
Echinococcus multilocularis cathepsin L cysteine protease 0.1214 0.3958 0.3958
Onchocerca volvulus 0.1214 0.3958 1
Brugia malayi Hemopexin family protein 0.0033 0.0065 0.0065
Brugia malayi Calmodulin-like protein 0.0103 0.0295 0.0295
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.044 0.1406 0.1406
Onchocerca volvulus Peroxidase homolog 0.0066 0.0172 0.0434
Trypanosoma brucei proteasome beta 6 subunit 0.006 0.0153 0.0292
Brugia malayi B-box zinc finger family protein 0.0019 0.0016 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0341 0.1081 0.1076
Onchocerca volvulus Putative nachr subunit 0.0075 0.0203 0.0513
Trypanosoma brucei trypanothione reductase 0.0097 0.0274 0.0525
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0005 0.0005
Schistosoma mansoni peptidylglycine monooxygenase 0.0377 0.1199 0.1195
Plasmodium falciparum glutathione reductase 0.0097 0.0274 0.0651
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0446 0.1425 0.1425
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1047 0.3409 0.3397
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0301 0.0948 0.0944
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0711 0.2298 0.2298
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3046 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0421 0.0416
Entamoeba histolytica cysteine proteinase, putative 0.0678 0.219 0.5515
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0075 0.0203 0.0203
Toxoplasma gondii proteasome subunit beta type 1, putative 0.006 0.0153 0.0379
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Loa Loa (eye worm) hypothetical protein 0.0377 0.1199 0.1199
Entamoeba histolytica hypothetical protein 0.0041 0.0089 0.0184
Toxoplasma gondii calcium-dependent protein kinase 0.0106 0.0304 0.0762
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0005 0.000000011593
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0076 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Onchocerca volvulus 0.0301 0.0948 0.2395
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0773 0.2505 0.2492
Loa Loa (eye worm) acetyltransferase 0.0153 0.0459 0.0459
Schistosoma mansoni ef hand domain family member A2 0.0103 0.0295 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0301 0.0948 0.2363
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0086
Echinococcus granulosus dna polymerase eta 0.0047 0.011 0.011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0044 0.0099 0.0094
Giardia lamblia Cysteine protease 0.0301 0.0948 0.2498
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0103 0.0295 0.029
Loa Loa (eye worm) cathepsin B 0.115 0.3748 0.3748
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0065 0.0123
Echinococcus granulosus cathepsin l cysteine peptidase 0.1214 0.3958 0.3958
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0301 0.0948 0.2387
Echinococcus granulosus intermediate filament protein 0.0028 0.0048 0.0048
Brugia malayi cathepsin L-like cysteine proteinase 0.0301 0.0948 0.0948
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0245 0.0763 1
Trypanosoma brucei metacaspase MCA3 0.0019 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.1698 0.5554 0.5554
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Leishmania major calpain family cysteine protease-like protein 0.0558 0.1794 0.3429
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.295
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0674 0.2179 0.2165
Plasmodium falciparum cysteine proteinase falcipain 1 0.0678 0.219 0.5514
Loa Loa (eye worm) RecQ helicase 0.0022 0.0029 0.0029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0473 0.1515 0.15
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0301 0.0948 0.2363
Schistosoma mansoni hypothetical protein 0.0103 0.0295 0.029
Onchocerca volvulus 0.004 0.0086 0.0217
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Brugia malayi MH2 domain containing protein 0.0017 0.0012 0.0012
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1801 0.5894 0.5892
Trypanosoma cruzi small myristoylated protein 1-2 0.0373 0.1185 0.117
Schistosoma mansoni rab 0.0103 0.0295 0.029
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.008 0.0079
Leishmania major cathepsin L-like protease 0.159 0.5198 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0034 0.0034
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.008 0.0159
Schistosoma mansoni Smad4 0.0017 0.0012 0.0008
Toxoplasma gondii PAN domain-containing protein 0.003 0.0053 0.0127
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0017 0.0017
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1047 0.3409 0.3397
Brugia malayi Death domain containing protein 0.0015 0.0005 0.0004
Brugia malayi B-box type zinc-finger protein ncl-1 0.0019 0.0016 0.0016
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0421 0.0421
Schistosoma mansoni acetylcholine receptor subunit beta 0.0035 0.0069 0.0065
Trichomonas vaginalis centrin, putative 0.0103 0.0295 0.0705
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0025 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0035 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0034 0.0034
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0019 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0034 0.0034
Brugia malayi larval opioid receptor 0.0024 0.0034 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0065 0.0153
Brugia malayi cathepsin F-like cysteine proteinase 0.0301 0.0948 0.0948
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0034 0.0034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0075 0.0203 0.0199
Trypanosoma cruzi centrin, putative 0.0112 0.0323 0.0306
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0065 0.2264
Echinococcus multilocularis serotonin receptor 0.0024 0.0034 0.0034
Leishmania major small myristoylated protein-1 0.0373 0.1185 0.2254
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0019 0.0016 0.0011
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0103 0.0295 0.0566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0678 0.219 0.4212
Schistosoma mansoni opsin-like receptor 0.0024 0.0034 0.0029
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0022 0.0012
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0025 0.0025
Onchocerca volvulus 0.0106 0.0304 0.0767
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0316 0.0997 0.1916
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0034 0.0029
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0053 0.0053
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Plasmodium vivax SET domain protein, putative 0.0064 0.0165 0.0405
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0301 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.0652
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0301 0.0948 0.2498
Leishmania major cathepsin L-like protease 0.1214 0.3958 0.7607
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0053 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0025 0.0025
Brugia malayi Matrixin family protein 0.0057 0.0143 0.0143
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0316 0.0997 0.0982
Echinococcus granulosus Smad4 0.0017 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0044 0.0099 0.0095
Echinococcus multilocularis Tolloid protein 1 0.0045 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.004 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0076 0.0059
Loa Loa (eye worm) trypsin family protein 0.004 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, putative 0.0558 0.1794 0.3449
Echinococcus multilocularis caspase 2 0.0063 0.0161 0.0161
Schistosoma mansoni neuronal calcium sensor 0.0103 0.0295 0.029
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.111 0.1095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0912 0.2962 0.5683
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0341 0.1081 0.2699
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1214 0.3958 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0017 0.0017
Onchocerca volvulus 0.003 0.0053 0.0133
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0075 0.0203 0.0199
Trypanosoma brucei metacaspase 0.0019 0.0017 0.0031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.022 0.0682 0.8863
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0036 0.0036
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0025 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0971 0.3156 0.6072
Echinococcus granulosus glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0053 0.0053
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.022 0.0682 0.8914
Echinococcus multilocularis calpain 7 (C02 family) 0.0773 0.2505 0.2505
Brugia malayi Cathepsin L-like precursor 0.0837 0.2716 0.2716
Onchocerca volvulus Chorion peroxidase homolog 0.0066 0.0172 0.0434
Echinococcus granulosus sodium channel protein 0.0037 0.0076 0.0076
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.013 0.0129
Mycobacterium tuberculosis Conserved protein 0.0038 0.008 0.0848
Toxoplasma gondii cathepsin B 0.115 0.3748 0.9468
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Onchocerca volvulus 0.0066 0.0172 0.0434
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.008 0.2999
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0042 0.0064
Schistosoma mansoni hypothetical protein 0.0024 0.0034 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0421 0.0421
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.1794 0.178
Brugia malayi steroid hormone receptor 0.0021 0.0025 0.0025
Toxoplasma gondii calmodulin CAM1 0.0106 0.0304 0.0762
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0035 0.0069 0.0069
Leishmania major trypanothione reductase 0.0097 0.0274 0.0495
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0103 0.0295 0.0295
Echinococcus multilocularis serotonin receptor 0.0024 0.0034 0.0034
Mycobacterium ulcerans proteasome PrcB 0.0079 0.0215 1
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Leishmania major kinesin, putative 0.0432 0.1379 0.263
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0041 0.0089 0.0088
Echinococcus granulosus hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.1214 0.3958 0.3958
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.008 0.0063
Leishmania major cysteine peptidase A (CPA) 0.1214 0.3958 0.7607
Schistosoma mansoni hypothetical protein 0.0132 0.0391 0.0386
Schistosoma mansoni opsin-like receptor 0.0024 0.0034 0.0029
Trypanosoma brucei calpain, putative 0.0341 0.1081 0.2077
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0034 0.0034
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0558 0.1794 0.3449
Brugia malayi putative neuropeptide receptor 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0301 0.0948 0.2363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0837 0.2716 0.6849
Echinococcus granulosus calpain 5 0.0773 0.2505 0.2505
Onchocerca volvulus 0.0064 0.0165 0.0416
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0065 0.0159
Trypanosoma cruzi calmodulin, putative 0.0103 0.0295 0.0278
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0034 0.0034
Trypanosoma brucei calpain-like protein, putative 0.0773 0.2505 0.4818
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0022 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Mycobacterium leprae conserved hypothetical protein 0.0038 0.008 0.0419
Echinococcus multilocularis Ankyrin 0.0015 0.0005 0.0005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Trypanosoma brucei Component of motile flagella 41 0.0103 0.0295 0.0566
Onchocerca volvulus 0.0103 0.0295 0.0744
Echinococcus multilocularis EF hand domain containing family member A2 0.0103 0.0295 0.0295
Trypanosoma brucei protein I/6 0.0103 0.0295 0.0566
Brugia malayi sulfakinin receptor protein 0.0024 0.0034 0.0034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0867 0.2812 0.5396
Echinococcus multilocularis nAChR subunit 0.0041 0.0089 0.0089
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0377 0.1197 0.1197
Echinococcus granulosus EF hand domain containing family member A2 0.0106 0.0304 0.0304
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0034 0.0034
Echinococcus granulosus calbindin 32 0.0106 0.0304 0.0304
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0075 0.0203 0.0203
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0459 0.0458
Schistosoma mansoni hypothetical protein 0.0017 0.001 0.0006
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0012 0.0008
Schistosoma mansoni cpg binding protein 0.0032 0.006 0.0056
Echinococcus multilocularis calpain family protein 1, d 0.1266 0.413 0.413
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0064 0.0164 0.0404
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1214 0.3958 0.3958
Onchocerca volvulus 0.1214 0.3958 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Mycobacterium leprae Probable lipase LipE 0.0038 0.008 0.0419
Echinococcus multilocularis nAChR subunit 0.0075 0.0203 0.0203
Schistosoma mansoni dopamine-beta-monooxygenase 0.0377 0.1199 0.1195
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0005 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.004 0.0086 0.0082
Echinococcus multilocularis neuronal calcium sensor 0.0103 0.0295 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1214 0.3958 1
Brugia malayi calpain D 0.0341 0.1081 0.108
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0034 0.0029
Brugia malayi Peroxidasin 0.0066 0.0172 0.0172
Leishmania major DNA polymerase eta, putative 0.0047 0.011 0.0179
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0034 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0678 0.219 0.5515
Brugia malayi Papain family cysteine protease containing protein 0.0301 0.0948 0.0948
Loa Loa (eye worm) calpain D 0.0341 0.1081 0.1081
Loa Loa (eye worm) hypothetical protein 0.0377 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Schistosoma mansoni neuronal calcium sensor 0.0103 0.0295 0.029
Schistosoma mansoni lamin 0.0028 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Leishmania major programmed cell death 6 protein-like protein 0.0103 0.0295 0.0537
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0069
Trypanosoma brucei calpain-like protein, putative 0.1047 0.3409 0.6557
Loa Loa (eye worm) B-box zinc finger family protein 0.0019 0.0016 0.0016
Schistosoma mansoni amine GPCR 0.0024 0.0034 0.0029
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0216 0.0668 0.1256
Trichomonas vaginalis calcium binding proteins, putative 0.0103 0.0295 0.0705
Brugia malayi Dopamine receptor protein 1 0.0024 0.0034 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0034 0.0034
Trichomonas vaginalis calpain, putative 0.0341 0.1081 0.2699
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0034 0.0034
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0086 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0333 0.1053 0.1053
Leishmania major cathepsin L-like protease 0.1214 0.3958 0.7607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0025 0.0025
Echinococcus multilocularis neurocalcin 0.0103 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Onchocerca volvulus Peroxidasin homolog 0.0066 0.0172 0.0434
Plasmodium vivax hypothetical protein, conserved 0.0106 0.0304 0.0757
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0017 0.0017
Entamoeba histolytica cysteine proteinase, putative 0.0678 0.219 0.5515
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0034 0.0034
Plasmodium vivax proteasome subunit beta type-5, putative 0.0079 0.0215 0.053
Echinococcus multilocularis somatostatin receptor 0.0024 0.0034 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0038 0.008 0.0189
Brugia malayi B-box type zinc-finger protein ncl-1 0.0019 0.0016 0.0016
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0034 0.0034
Brugia malayi beta-lactamase family protein 0.0038 0.008 0.0079
Brugia malayi Cathepsin L-like precursor 0.1214 0.3958 0.3958
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0013 0.0009
Echinococcus multilocularis cathepsin b 0.3046 1 1
Onchocerca volvulus 0.004 0.0086 0.0217
Trichomonas vaginalis calcineurin B subunit, putative 0.0103 0.0295 0.0705
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0301 0.0948 0.0948
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0859 0.165
Loa Loa (eye worm) Smad1 0.0017 0.0012 0.0012
Toxoplasma gondii cathepsin CPC2 0.0301 0.0948 0.2391
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0216 0.0668 0.0652
Echinococcus multilocularis cathepsin L 0.0301 0.0948 0.0948
Brugia malayi calpain family protein 1 0.1698 0.5554 0.5554
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0034 0.0034
Echinococcus granulosus neuropeptide receptor 0.0024 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0341 0.1081 0.2077
Schistosoma mansoni smad1 5 8 and 0.0017 0.0012 0.0008
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0099 0.0099
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0925 0.3004 0.3004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Leishmania major i/6 autoantigen-like protein 0.0103 0.0295 0.0537
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0103 0.0295 0.0707
Schistosoma mansoni hypothetical protein 0.0103 0.0295 0.029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0203 0.0203
Brugia malayi neuropeptide F receptor 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0837 0.2716 0.6849
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Echinococcus multilocularis programmed cell death protein 0.0112 0.0323 0.0323
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0034 0.0034
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.1283
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0055 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0065 0.017 0.0165
Schistosoma mansoni centrin 0.0103 0.0295 0.029
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0047
Schistosoma mansoni amine GPCR 0.0024 0.0034 0.0029
Schistosoma mansoni hypothetical protein 0.0017 0.001 0.0006
Plasmodium vivax metacaspase 1, putative 0.0019 0.0017 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0674 0.2179 0.2165
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0075 0.0203 0.0203
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0301 0.0948 0.0948
Schistosoma mansoni cathepsin F (C01 family) 0.0837 0.2716 0.2713
Onchocerca volvulus 0.0837 0.2716 0.6862
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0301 0.0948 0.2363
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0274 0.0257
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Brugia malayi hypothetical protein 0.0024 0.0034 0.0034
Plasmodium falciparum serine repeat antigen 3 0.0301 0.0948 0.2363
Schistosoma mansoni nAChR subunit 0.0035 0.0069 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0065 0.0123
Onchocerca volvulus 0.0024 0.0034 0.0085
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1214 0.3958 0.3958
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.035 0.111 0.2774
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0859 0.0843
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0075 0.0203 0.0203
Echinococcus multilocularis cathepsin L 0.0678 0.219 0.219
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0034 0.0034
Echinococcus multilocularis calcium uptake protein 1 0.0106 0.0304 0.0304
Mycobacterium tuberculosis Putative ferredoxin reductase 0.022 0.0682 0.8914
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0025 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0022 0.004
Leishmania major calmodulin, putative 0.0103 0.0295 0.0537
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0301 0.0948 0.2387
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0035 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0063 0.0163 0.0158
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0301 0.0948 0.2363
Plasmodium falciparum thioredoxin reductase 0.0097 0.0274 0.0651
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0539 0.1732 0.1718
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0076 0.0059
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0103 0.0295 0.0278
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0053 0.0127
Loa Loa (eye worm) hypothetical protein 0.0041 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0017 0.001 0.0006
Entamoeba histolytica cysteine protease, putative 0.0678 0.219 0.5515
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0029 0.003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0065 0.0123
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1214 0.3958 0.3958
Trypanosoma brucei cysteine peptidase C (CPC) 0.115 0.3748 0.721
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Echinococcus granulosus serotonin receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0558 0.1794 0.178
Brugia malayi Serotonin receptor 0.0024 0.0034 0.0034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0065 0.0048
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0558 0.1794 0.178
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0034 0.0034
Schistosoma mansoni neuronal calcium sensor 0.0103 0.0295 0.029
Leishmania major hypothetical protein, conserved 0.0106 0.0304 0.0554
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0065 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.115 0.3748 0.3745
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0203 0.0203
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0065 0.0048
Loa Loa (eye worm) hypothetical protein 0.0064 0.0165 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.159 0.5198 1
Entamoeba histolytica calpain family cysteine protease, putative 0.0341 0.1081 0.27
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0103 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.016
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0034 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Giardia lamblia Cathepsin B precursor 0.0301 0.0948 0.2498
Trichomonas vaginalis conserved hypothetical protein 0.0301 0.0948 0.2363
Giardia lamblia Cathepsin B precursor 0.115 0.3748 1
Plasmodium falciparum serine repeat antigen 5 0.0301 0.0948 0.2363
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0773 0.2505 0.2492
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0065 0.2264
Plasmodium vivax vivapain-2 0.1214 0.3958 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.001 0.001
Plasmodium vivax glutathione reductase, putative 0.0097 0.0274 0.068
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.008 0.0159
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0301 0.0948 0.2387
Entamoeba histolytica cysteine protease, putative 0.0301 0.0948 0.2365
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0075 0.0203 0.0203
Echinococcus granulosus cysteine protease 0.0678 0.219 0.219
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0074 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.016
Echinococcus multilocularis calumenin 0.0106 0.0304 0.0304
Echinococcus multilocularis calpain 5 0.0773 0.2505 0.2505
Echinococcus multilocularis brain tumor protein 0.0019 0.0016 0.0016
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0024 0.0033 0.0028
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0301 0.0948 0.2387
Brugia malayi Trypsin family protein 0.004 0.0086 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0022 0.0005
Trichomonas vaginalis calmodulin, putative 0.0106 0.0304 0.0728
Onchocerca volvulus 0.003 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.0377 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0086
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.006 0.0153 0.0148
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.021 0.021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0678 0.219 0.2186
Leishmania major hypothetical protein, conserved 0.0026 0.0042 0.0049
Giardia lamblia Cathepsin L precursor 0.0301 0.0948 0.2498
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.004 0.0086 0.0082
Onchocerca volvulus 0.0024 0.0034 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0301 0.0948 0.2363
Leishmania major phospholipase c-like protein 0.0103 0.0295 0.0537
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0034 0.0029
Brugia malayi KE2 family protein 0.0063 0.0163 0.0163
Onchocerca volvulus 0.0041 0.0089 0.0223
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0079 0.0215 0.0532
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0034 0.0034
Leishmania major small myristoylated protein 4, putative 0.0588 0.1894 0.3622
Onchocerca volvulus 0.0033 0.0065 0.0164
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0022 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0025 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0034 0.0034
Giardia lamblia Cathepsin B precursor 0.115 0.3748 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.0391 0.0391
Echinococcus multilocularis centrin 2 0.0103 0.0295 0.0295
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.008 0.0151
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0079 0.0215 0.0411
Brugia malayi calpain family protein 1 0.1698 0.5554 0.5554
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0022 0.0005
Trypanosoma cruzi I/6 autoantigen, putative 0.0103 0.0295 0.0278
Onchocerca volvulus Matrix metalloproteinase homolog 0.0052 0.0127 0.0321
Entamoeba histolytica calmodulin, putative 0.0103 0.0295 0.0707
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0034 0.0029
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0025 0.0025
Plasmodium vivax serine-repeat antigen (SERA) 0.0301 0.0948 0.2387
Brugia malayi PAN domain containing protein 0.003 0.0053 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0034 0.0029
Echinococcus granulosus glycine receptor subunit alpha 1 0.0075 0.0203 0.0203
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0539 0.1732 0.331
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0301 0.0948 0.2363
Onchocerca volvulus 0.0075 0.0203 0.0513
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0274 0.0859 0.165
Schistosoma mansoni hypothetical protein 0.0024 0.0034 0.0029
Schistosoma mansoni nAChR subunit 0.0075 0.0203 0.0199
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0025 0.0025
Mycobacterium ulcerans hypothetical protein 0.004 0.0086 0.3342
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1741 0.5695 0.5695
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0063 0.0161 0.0161
Brugia malayi cathepsin F-like cysteine proteinase 0.0377 0.1197 0.1196
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.0754 0.0754
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0301 0.0948 0.2363
Brugia malayi MH1 domain containing protein 0.0017 0.0012 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0034 0.0034
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0037 0.0076 0.0115
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0075 0.0203 0.0203
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0301 0.0948 0.2498
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0034 0.0029
Brugia malayi Matrixin family protein 0.0024 0.0033 0.0032
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0079 0.0215 0.0198
Entamoeba histolytica calpain large subunit domain III containing protein 0.0432 0.1379 0.3458
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0216 0.0668 0.1283
Trichomonas vaginalis calmodulin, putative 0.0103 0.0295 0.0705
Brugia malayi MH1 domain containing protein 0.0017 0.0012 0.0012
Schistosoma mansoni peroxidasin 0.0066 0.0172 0.0167
Brugia malayi Papain family cysteine protease containing protein 0.1214 0.3958 0.3958

Activities

Activity type Activity value Assay description Source Reference
Efficacy (functional) Efficacy against human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Efficacy (functional) 0 Efficacy against human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Efficacy (functional) = 0.1 % Efficacy against recombinant human GABA-Aalpha1 receptor plus beta3gamma2 as measured by modulation of chloride ion flux ChEMBL. 16406613
Efficacy (functional) = 0.1 % Efficacy against recombinant human GABA-Aalpha1 receptor plus beta3gamma2 as measured by modulation of chloride ion flux ChEMBL. 16406613
Efficacy (functional) = 0.19 % Efficacy against recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16406613
Efficacy (functional) = 0.19 % Efficacy against recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16406613
Efficacy (functional) = 0.53 % Efficacy against recombinant human GABA-Aalpha3 receptor plus beta3gamma2 as measured by modulation of chloride ion flux ChEMBL. 16406613
Efficacy (functional) = 0.53 % Efficacy against recombinant human GABA-Aalpha3 receptor plus beta3gamma2 as measured by modulation of chloride ion flux ChEMBL. 16406613
Efficacy (functional) = 0.59 % Efficacy against recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16406613
Efficacy (functional) = 0.59 % Efficacy against recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16406613
Efficacy (functional) = 20 % Efficacy against human recombinant GABAA alpha1 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Efficacy (functional) = 20 % Efficacy against human recombinant GABAA alpha1 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Efficacy (functional) = 69 % Efficacy against human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Efficacy (functional) = 69 % Efficacy against human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells by whole cell patch clamp method ChEMBL. 16392789
Ki (binding) Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha2 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) 0 Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha2 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.21 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.21 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.33 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.33 nM Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells ChEMBL. 16406613
Ki (binding) = 0.33 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.33 nM Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells ChEMBL. 16406613
Ki (binding) = 0.66 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.66 nM Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells ChEMBL. 16406613
Ki (binding) = 0.66 nM Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta3gamma2 expressed in L(tk-) cells ChEMBL. 16392789
Ki (binding) = 0.66 nM Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells ChEMBL. 16406613
Stabilty (ADMET) = 100 % Stability in dog liver microsomes at 1 uM ChEMBL. 16406613

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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