Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Plasmodium vivax | vivapain-2 | 0.0169 | 0.9924 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0169 | 0.9924 | 0.9895 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Plasmodium vivax | vivapain-2 | 0.0169 | 0.9924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.5023 | 0.5061 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0169 | 0.9924 | 0.9924 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0169 | 0.9924 | 0.9895 |
Echinococcus granulosus | cathepsin l1 | 0.0169 | 0.9924 | 0.9895 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0113 | 0.5023 | 0.5061 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0169 | 0.9924 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0113 | 0.5023 | 0.3148 |
Plasmodium vivax | vivapain-1 | 0.0087 | 0.2736 | 0.2757 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.5023 | 0.5061 |
Loa Loa (eye worm) | fibroinase | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0169 | 0.9924 | 0.9924 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0169 | 0.9924 | 0.9895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0087 | 0.2736 | 0.2736 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0087 | 0.2736 | 0.2757 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.5023 | 0.5061 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0087 | 0.2736 | 0.2757 |
Toxoplasma gondii | cathepsin CPL | 0.0169 | 0.9924 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0169 | 0.9924 | 0.9895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0169 | 0.9924 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Plasmodium vivax | unspecified product | 0.0087 | 0.2736 | 0.2757 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.9924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0113 | 0.5023 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0169 | 0.9924 | 0.9895 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0087 | 0.2736 | 0.2736 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0113 | 0.5023 | 0.5023 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Plasmodium vivax | vivapain-3 | 0.0087 | 0.2736 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.9924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0169 | 0.9924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0169 | 0.9924 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0169 | 0.9924 | 0.9895 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0113 | 0.5023 | 0.5061 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0087 | 0.2736 | 0.2757 |
Loa Loa (eye worm) | ctsf protein | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0113 | 0.5023 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0087 | 0.2736 | 0.2757 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0087 | 0.2736 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | 0.0169 | 0.9924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0113 | 0.5023 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.9924 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0113 | 0.5023 | 0.5061 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0169 | 0.9924 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0113 | 0.5023 | 0.5061 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0169 | 0.9924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0169 | 0.9924 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0169 | 0.9924 | 0.9895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0169 | 0.9924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0087 | 0.2736 | 0.2736 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0087 | 0.2736 | 0.2757 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0113 | 0.5023 | 0.5061 |
Loa Loa (eye worm) | cysteine protease | 0.0169 | 0.9924 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0169 | 0.9924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0169 | 0.9924 | 0.5 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0169 | 0.9924 | 0.9895 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0087 | 0.2736 | 0.2757 |
Echinococcus multilocularis | geminin | 0.017 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0169 | 0.9924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.9924 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 | 16392829 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.