TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 372.811 | Formula: C14H18ClF3NO3S-
H donors: 1 H acceptors: 2 LogP: 4.66 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCCN[C@@H]1CCc2c(C1)cccc2OS(=O)(=O)C(F)(F)F.[Cl-]
InChi: 1S/C14H18F3NO3S.ClH/c1-2-8-18-11-6-7-12-10(9-11)4-3-5-13(12)21-22(19,20)14(15,16)17;/h3-5,11,18H,2,6-9H2,1H3;1H/p-1/t11-;/m1./s1
InChiKey: MGUKPLVYJHFUFY-RFVHGSKJSA-M

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide Y receptor	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide receptor A26	0.003	0.0012	0.0012
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.003	0.0012	0.0012
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	G protein coupled receptor 139	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide s receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Schistosoma mansoni	hypothetical protein	0.0072	0.0255	0.0243
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Echinococcus multilocularis	neuropeptide receptor A26	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Mycobacterium tuberculosis	Hypothetical protein	0.0447	0.2448	0.2423
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Brugia malayi	Dihydrofolate reductase	0.1741	1	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.003	0.0012	0.0012
Onchocerca volvulus		0.094	0.5325	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Loa Loa (eye worm)	hypothetical protein	0.0033	0.003	0.003
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptides capa receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.003	0.0012	0.0012
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Echinococcus multilocularis	G-protein coupled receptor, putative	0.003	0.0012	0.0012
Echinococcus multilocularis	neuropeptides capa receptor	0.003	0.0012	0.0012
Brugia malayi	Thrombospondin type 1 domain containing protein	0.0072	0.0255	0.0243
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	0.094	0.5325	0.5319
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	7tm_1 domain containing protein	0.003	0.0012	0.0012
Echinococcus granulosus	g protein coupled receptor	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Onchocerca volvulus		0.0072	0.0255	0.0457
Echinococcus multilocularis	neuropeptide Y receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.1673	0.9607	1
Echinococcus granulosus	sex peptide receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.0012	0.0012
Mycobacterium ulcerans	dihydrofolate reductase DfrA	0.1741	1	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.0012	0.0012
Echinococcus granulosus	G protein coupled receptor 139	0.003	0.0012	0.0012
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0033	0.003	0.0019
Loa Loa (eye worm)	melatonin receptor type 1A	0.003	0.0012	0.0012
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0033	0.003	0.0019
Echinococcus granulosus	tachykinin peptides receptor 99D	0.003	0.0012	0.0012
Brugia malayi	thymidylate synthase	0.094	0.5325	0.5319
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Brugia malayi	hypothetical protein	0.0447	0.2448	0.2439
Echinococcus granulosus	fmrfamide receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	dro:myosuppressin receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Mycobacterium leprae	PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT	0.0151	0.0721	0.0691
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.1673	0.9607	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.003	0.0012	0.0012
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0033	0.003	0.0019
Echinococcus granulosus	serotonin receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	neuropeptide F receptor	0.003	0.0012	0.0012
Echinococcus granulosus	g-protein coupled receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.003	0.0012	0.0012
Chlamydia trachomatis	dihydrofolate reductase	0.1741	1	0.5
Echinococcus granulosus	biogenic amine 5HT receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Onchocerca volvulus		0.0033	0.003	0.0035
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	thymidylate synthase	0.094	0.5325	0.5325
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	fmrfamide receptor	0.003	0.0012	0.0012
Echinococcus granulosus	biogenic amine 5HT receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Wolbachia endosymbiont of Brugia malayi	phosphoribosylamine--glycine ligase	0.0151	0.0721	1
Echinococcus granulosus	dro:myosuppressin receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide receptor	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptide Y receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	dihydrofolate reductase	0.1741	1	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.003	0.003
Mycobacterium ulcerans	thymidylate synthase	0.094	0.5325	0.531
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.1673	0.9607	0.5
Loa Loa (eye worm)	thrombospondin type 1 domain-containing protein	0.0072	0.0255	0.0255
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	g protein coupled receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	neuropeptide F receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	peptide allatostatin:somatostatin	0.003	0.0012	0.0012
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	sex peptide receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	dihydrofolate reductase	0.1741	1	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.003	0.0012	0.0012
Echinococcus granulosus	somatostatin receptor	0.003	0.0012	0.0012
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.003	0.0012	0.0012
Mycobacterium ulcerans	phosphoribosylamine--glycine ligase	0.0151	0.0721	0.0691
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.1673	0.9607	0.5
Mycobacterium leprae	DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE)	0.1741	1	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus multilocularis	neuropeptides capa receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Onchocerca volvulus		0.0033	0.003	0.0035
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	orexin receptor type 2	0.003	0.0012	0.0012
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus multilocularis	fmrfamide receptor	0.003	0.0012	0.0012
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.003	0.0012	0.0012
Echinococcus multilocularis	somatostatin receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	g protein coupled receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Brugia malayi	Type I phosphodiesterase / nucleotide pyrophosphatase family protein	0.0033	0.003	0.0019
Echinococcus multilocularis	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	G-protein coupled receptor	0.003	0.0012	0.0012
Echinococcus granulosus	orexin receptor type 2	0.003	0.0012	0.0012
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus granulosus	allatostatin A receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	TYRA-2 protein	0.003	0.0012	0.0012
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0033	0.003	0.003
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	g protein coupled receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.003	0.0012	0.0012
Echinococcus multilocularis	serotonin receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.003	0.0012	0.0012
Echinococcus granulosus	g protein coupled receptor	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.003	0.0012	0.0012
Echinococcus multilocularis	neuropeptide receptor	0.003	0.0012	0.0012
Mycobacterium tuberculosis	Probable thymidylate synthase ThyA (ts) (TSASE)	0.094	0.5325	0.531
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	g-protein coupled receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Loa Loa (eye worm)	G-protein coupled receptor	0.003	0.0012	0.0012
Echinococcus granulosus	7TM GPCR rhodopsin	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	alpha 1A adrenergic receptor	0.003	0.0012	0.0012
Echinococcus granulosus	tm gpcr rhodopsin	0.003	0.0012	0.0012
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.1673	0.9607	0.5
Echinococcus multilocularis	neuropeptide FF receptor 2	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.0012	0.0012
Schistosoma mansoni	dihydrofolate reductase	0.1741	1	1
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.003	0.0012	0.0012
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus granulosus	g protein coupled receptor	0.003	0.0012	0.0012
Echinococcus granulosus	neuropeptides capa receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus granulosus	thymidylate synthase	0.094	0.5325	0.5325
Echinococcus granulosus	dihydrofolate reductase	0.1741	1	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0033	0.003	0.003
Echinococcus multilocularis	allatostatin A receptor	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Mycobacterium tuberculosis	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	0.1741	1	1
Mycobacterium leprae	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)	0.094	0.5325	0.531
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.003	0.0012	0.0012
Echinococcus multilocularis	serotonin receptor	0.003	0.0012	0.0012
Echinococcus multilocularis	neuropeptide receptor	0.003	0.0012	0.0012
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.1673	0.9607	0.5
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.003	0.0012	0.0012
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0033	0.003	0.0019
Echinococcus multilocularis	neuropeptide s receptor	0.003	0.0012	0.0012
Onchocerca volvulus		0.0033	0.0032	0.0038
Loa Loa (eye worm)	hypothetical protein	0.003	0.0012	0.0012
Trichomonas vaginalis	conserved hypothetical protein	0.0447	0.2448	0.5
Loa Loa (eye worm)	thymidylate synthase	0.094	0.5325	0.5325

Activities

Activity type	Activity value	Assay description	Source	Reference
Control (functional)	= 78 %	Half-minimal decrease in the accumulation of DOPA (3,4-dihydroxyphenylalanine) in non pretreated rat limbic brainat dose 25 microM/kg	ChEMBL.	7731017
Control (functional)	= 83 %	Half-minimal decrease in the accumulation of 5-HTP (5-Hydroxytryptophan) in non pretreated rat striatal brain at dose 25 microM/kg	ChEMBL.	7731017
Control (functional)	= 98 %	Half-minimal decrease in the accumulation of DOPA (3,4-dihydroxyphenylalanine) in non pretreated rat striatal brain at dose 25 microM/kg	ChEMBL.	7731017
Control (functional)	= 101 %	In vitro binding affinity towards 5-hydroxytryptamine 1D receptor beta by using [3H]-5-HT as radioligand	ChEMBL.	7731017
Control (functional)	= 130 %	post-synaptic activity was determined by locomotor activity (LMA) in Non pretreated rats	ChEMBL.	7731017
Ki (binding)	= 120 nM	In vitro binding affinity towards Dopamine receptor D3 by using [3H]-spiperone as radioligand	ChEMBL.	7731017
Ki (binding)	> 1000 nM	In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligand	ChEMBL.	7731017
Ki (binding)	> 1500 nM	In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]-5-HT as radioligand	ChEMBL.	7731017
Ki (binding)	> 1500 nM	In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]-5-HT as radioligand	ChEMBL.	7731017
Ki (binding)	> 3800 nM	In vitro binding affinity towards Dopamine receptor D2 by using [3H]-U-86,170 as radioligand	ChEMBL.	7731017
No. of rats with 5-HT syndrome (functional)	= 0	behavioral syndrome(flat body posture and forepaw treading) at 25 mg/Kg	ChEMBL.	7731017

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 136615

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 35118