Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Hepatitis C virus | Hepatitis C virus NS5B RNA-dependent RNA polymerase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | DNA-directed RNA polymerase subunit beta | 0.0841 | 0.5 | 0.5 |
Mycobacterium ulcerans | DNA-directed RNA polymerase subunit beta | 0.0841 | 0.5 | 0.5 |
Mycobacterium leprae | DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) | 0.0841 | 0.5 | 0.5 |
Mycobacterium tuberculosis | DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) | 0.0841 | 0.5 | 0.5 |
Plasmodium falciparum | DNA-directed RNA polymerase subunit beta, putative | 0.0841 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | DNA-directed RNA polymerase subunit beta/beta' | 0.0841 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.