Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | squalene epoxidase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0293 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0293 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0293 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0293 | 1 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0293 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0293 | 1 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0293 | 1 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0293 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0293 | 1 | 1 |
Plasmodium vivax | apical sushi protein, putative | 0.0158 | 0 | 0.5 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Echinococcus granulosus | mitogen activated protein kinase | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0293 | 1 | 0.5 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.1305 | 0.1305 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0293 | 1 | 1 |
Plasmodium falciparum | apical sushi protein | 0.0158 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0293 | 1 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Trypanosoma brucei | protein kinase, putative | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0293 | 1 | 1 |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Onchocerca volvulus | 0.0158 | 0 | 0.5 | |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0293 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.