TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 432.555 | Formula: C27H32N2O3
H donors: 2 H acceptors: 1 LogP: 6.24 Rotable bonds: 12
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)NCCNC(=O)C(Oc1ccccc1c1ccccc1)CC(C)C
InChi: 1S/C27H32N2O3/c1-20(2)19-26(27(30)29-18-17-28-22-13-15-23(31-3)16-14-22)32-25-12-8-7-11-24(25)21-9-5-4-6-10-21/h4-16,20,26,28H,17-19H2,1-3H3,(H,29,30)
InChiKey: BQUFZKSFNJHBFQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	cathepsin K	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania donovani	cysteine peptidase A (CBA)	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cysteine protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium falciparum	cysteine proteinase falcipain 2b	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium berghei	berghepain-2	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cruzipain precursor, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana		Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana	cathepsin L-like protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Entamoeba histolytica	cysteine protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	cysteine protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana	cysteine peptidase A (CBA)	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium yoelii	berghepain-2	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania braziliensis	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus	Cathepsin L homolog	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium vivax	vivapain-2	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus granulosus	cathepsin l1	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana	cathepsin L-like protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cysteine peptidase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma mansoni	cathepsin F (C01 family)	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Papain family cysteine protease containing protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cysteine peptidase A (CPA)	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus granulosus	cathepsin L cysteine proteinase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania infantum	cysteine peptidase A (CPA)	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cathepsin l cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei gambiense	cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium vivax	vivapain-2	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	fibroinase	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium knowlesi	knowpain-2	Get druggable targets OG5_126607	All targets in OG5_126607
Entamoeba histolytica	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus	Cathepsin F homolog	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania braziliensis	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus	Cathepsin L homolog	Get druggable targets OG5_126607	All targets in OG5_126607
Entamoeba histolytica	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana		Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma mansoni	cathepsin F (C01 family)	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium falciparum	cysteine proteinase falcipain 2a	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium knowlesi	knowpain-3	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium falciparum	cysteine proteinase falcipain 3	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cysteine peptidase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cathepsin L cysteine protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus granulosus	cathepsin l1	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania infantum	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Onchocerca volvulus		Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana		Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Cryptosporidium parvum	cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana		Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma japonicum	ko:K01373 cathepsin F [EC3.4.22.41], putative	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania mexicana		Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania braziliensis	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania infantum	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	papain family cysteine protease containing protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei gambiense	cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Plasmodium knowlesi	knowpain-4	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei gambiense	cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine protease, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like cysteine proteinase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Toxoplasma gondii	cathepsin CPL	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cathepsin l cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus granulosus	cathepsin l cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma mansoni	cathepsin F (C01 family)	Get druggable targets OG5_126607	All targets in OG5_126607
Neospora caninum	Cathepsin L, related	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cysteine peptidase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma japonicum	expressed protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Cryptosporidium hominis	cryptopain precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania major	cathepsin L-like protease	Get druggable targets OG5_126607	All targets in OG5_126607
Leishmania braziliensis	cysteine peptidase A (CPA)	Get druggable targets OG5_126607	All targets in OG5_126607
Entamoeba histolytica	cysteine proteinase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	ctsf protein	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cathepsin L cysteine protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma cruzi	cysteine peptidase, putative	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126607	All targets in OG5_126607
Brugia malayi	Cathepsin L-like precursor	Get druggable targets OG5_126607	All targets in OG5_126607
Theileria parva	cysteine proteinase	Get druggable targets OG5_126607	All targets in OG5_126607
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	Get druggable targets OG5_126607	All targets in OG5_126607
Echinococcus multilocularis	cysteine protease	Get druggable targets OG5_126607	All targets in OG5_126607
Trypanosoma congolense	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	Get druggable targets OG5_126607	All targets in OG5_126607
Schistosoma japonicum	Cathepsin L-like proteinase precursor, putative	Get druggable targets OG5_126607	All targets in OG5_126607

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	cysteine proteinase falcipain 1	cathepsin K	329 aa	349 aa	33.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Plasmodium vivax	unspecified product	0.0014	0.0044	0.0044
Echinococcus granulosus	cathepsin L	0.0014	0.0044	0.0034
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.001	0.0012	0.0013
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.016	0.015
Entamoeba histolytica	adenosine deaminase, putative	0.1135	1	1
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	0.0022	0.0112	0.0112
Plasmodium vivax	vivapain-3	0.0014	0.0044	0.0044
Onchocerca volvulus		0.0027	0.016	0.015
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.001	0.0012	0.0013
Leishmania major	cysteine peptidase A (CPA)	0.0027	0.016	0.015
Echinococcus multilocularis	AMP deaminase 2	0.1061	0.9344	0.9343
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Trypanosoma brucei	AMP deaminase, putative	0.1061	0.9344	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Onchocerca volvulus		0.0092	0.0741	0.0731
Entamoeba histolytica	AMP deaminase, putative	0.1061	0.9344	0.9341
Echinococcus multilocularis	adenosine deaminase	0.1135	1	1
Brugia malayi	cathepsin L-like precursor	0.0018	0.0081	0.0081
Brugia malayi	Carboxylesterase family protein	0.0547	0.4776	0.4776
Echinococcus granulosus	cathepsin l1	0.0027	0.016	0.015
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0014	0.0044	0.0044
Schistosoma mansoni	acetylcholinesterase	0.0092	0.0741	0.0741
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Echinococcus granulosus	acetylcholinesterase	0.0547	0.4776	0.4771
Echinococcus granulosus	para nitrobenzyl esterase	0.0092	0.0741	0.0731
Echinococcus multilocularis	eukaryotic elongation factor 2 kinase	0.0019	0.009	0.008
Schistosoma mansoni	AMP deaminase	0.1061	0.9344	0.9344
Echinococcus granulosus	cathepsin L cysteine protease	0.0014	0.0044	0.0034
Loa Loa (eye worm)	carboxylesterase	0.0092	0.0741	0.0741
Echinococcus granulosus	adenosine deaminase	0.1135	1	1
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.016	0.0172
Leishmania major	adenosine monophosphate deaminase, putative,AMP deaminase, putative	0.1061	0.9344	0.9343
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0092	0.0741	0.0731
Plasmodium vivax	vivapain-2	0.0027	0.016	0.016
Trypanosoma cruzi	adenosine monophosphate deaminase, putative	0.1061	0.9344	1
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Brugia malayi	Papain family cysteine protease containing protein	0.0027	0.016	0.016
Treponema pallidum	adenosine deaminase	0.1135	1	0.5
Leishmania major	AMP deaminase, putative,adenosine monophosphate deaminase-like protein	0.1061	0.9344	0.9343
Trypanosoma cruzi	cysteine proteinase, putative	0.0014	0.0044	0.0047
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0092	0.0741	0.0741
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0027	0.016	0.0117
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0018	0.0081	0.0071
Loa Loa (eye worm)	carboxylesterase	0.0547	0.4776	0.4776
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Loa Loa (eye worm)	carboxylesterase	0.0092	0.0741	0.0741
Leishmania major	protein kinase, putative	0.001	0.0012	0.0002
Echinococcus granulosus	carboxylesterase 5A	0.0547	0.4776	0.4771
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	Carboxylesterase family protein	0.0092	0.0741	0.0741
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	Cathepsin L-like precursor	0.0018	0.0081	0.0081
Trypanosoma cruzi	AMP deaminase, putative	0.1061	0.9344	1
Trypanosoma cruzi	PAS-domain containing phosphoglycerate kinase, putative	0.001	0.001	0.0011
Schistosoma mansoni	BC026374 protein (S09 family)	0.0092	0.0741	0.0741
Echinococcus multilocularis	carboxylesterase 5A	0.0547	0.4776	0.4771
Echinococcus multilocularis	cysteine protease	0.0027	0.016	0.015
Onchocerca volvulus		0.0092	0.0741	0.0731
Plasmodium falciparum	adenosine deaminase	0.1135	1	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.016	0.015
Onchocerca volvulus		0.0029	0.0176	0.0166
Loa Loa (eye worm)	hypothetical protein	0.001	0.001	0.001
Onchocerca volvulus		0.0558	0.4874	0.4869
Schistosoma mansoni	hypothetical protein	0.0019	0.0093	0.0093
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0018	0.0081	0.0081
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	Carboxylesterase family protein	0.0547	0.4776	0.4776
Leishmania major	protein kinase, putative	0.001	0.0012	0.0002
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.016	0.015
Brugia malayi	Cathepsin L-like precursor	0.0018	0.0081	0.0081
Schistosoma mansoni	adenosine deaminase	0.1135	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Plasmodium vivax	vivapain-1	0.0014	0.0044	0.0044
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0027	0.016	0.016
Trypanosoma cruzi	adenosine monophosphate deaminase-like protein, putative	0.1061	0.9344	1
Trypanosoma brucei	adenosine monophosphate deaminase, putative	0.1061	0.9344	1
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Echinococcus granulosus	cathepsin l1	0.0018	0.0081	0.0071
Onchocerca volvulus		0.0027	0.016	0.015
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0092	0.0741	0.0741
Plasmodium falciparum	AMP deaminase, putative	0.1061	0.9344	0.9341
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.016	0.0172
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	hypothetical protein	0.0092	0.0741	0.0741
Trypanosoma cruzi	AMP deaminase, putative	0.1061	0.9344	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0027	0.016	0.016
Loa Loa (eye worm)	hypothetical protein	0.0019	0.009	0.009
Echinococcus multilocularis	acetylcholinesterase	0.0547	0.4776	0.4771
Entamoeba histolytica	AMP deaminase, putative	0.1061	0.9344	0.9341
Onchocerca volvulus		0.0092	0.0741	0.0731
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0027	0.016	0.015
Loa Loa (eye worm)	cysteine protease	0.0027	0.016	0.016
Brugia malayi	Papain family cysteine protease containing protein	0.0014	0.0044	0.0044
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0547	0.4776	0.4776
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Echinococcus granulosus	cysteine protease	0.0014	0.0044	0.0034
Onchocerca volvulus		0.0027	0.016	0.015
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0092	0.0741	0.0741
Echinococcus granulosus	BC026374 protein S09 family	0.0092	0.0741	0.0731
Echinococcus multilocularis	para nitrobenzyl esterase	0.0092	0.0741	0.0731
Onchocerca volvulus	Cathepsin F homolog	0.0027	0.016	0.015
Echinococcus granulosus	neuroligin	0.0092	0.0741	0.0731
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.1135	1	1
Entamoeba histolytica	cysteine protease, putative	0.0027	0.016	0.0117
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0014	0.0044	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Loa Loa (eye worm)	hypothetical protein	0.013	0.1078	0.1078
Trypanosoma cruzi	AMP deaminase, putative	0.1061	0.9344	1
Loa Loa (eye worm)	hypothetical protein	0.0503	0.4391	0.4391
Loa Loa (eye worm)	hypothetical protein	0.0577	0.5047	0.5047
Onchocerca volvulus	Adenosine deaminase homolog	0.1135	1	1
Trypanosoma cruzi	AMP deaminase 2, putative	0.0558	0.4874	0.5216
Onchocerca volvulus		0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0018	0.0081	0.0071
Brugia malayi	bHLH-PAS transcription factor	0.0029	0.0176	0.0176
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0014	0.0044	0.0034
Trypanosoma cruzi	STE group serine/threonine-protein kinase, putative	0.001	0.0012	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0081	0.0081
Entamoeba histolytica	cysteine proteinase, putative	0.0027	0.016	0.0117
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0018	0.0081	0.0087
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0027	0.016	0.015
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0027	0.016	0.016
Echinococcus multilocularis	neuroligin	0.0092	0.0741	0.0731
Leishmania major	AMP deaminase, putative	0.1061	0.9344	0.9343
Loa Loa (eye worm)	hypothetical protein	0.0547	0.4776	0.4776
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0092	0.0741	0.0741
Leishmania major	myosin heavy chain kinase a-like protein	0.0019	0.009	0.008
Trypanosoma cruzi	myosin heavy chain kinase A, putative	0.0019	0.009	0.0097
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0014	0.0044	0.0044
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Loa Loa (eye worm)	AMP deaminase	0.1061	0.9344	0.9344
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Trypanosoma cruzi	myosin heavy chain kinase A, putative	0.0019	0.009	0.0097
Trypanosoma brucei	myosin heavy chain kinase A, putative	0.0019	0.009	0.005
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Brugia malayi	PAS domain containing protein	0.0039	0.0266	0.0266
Schistosoma mansoni	single-minded	0.0039	0.0266	0.0266
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.016	0.0172
Onchocerca volvulus		0.0027	0.016	0.015
Trypanosoma cruzi	PAS-domain containing phosphoglycerate kinase, putative	0.001	0.001	0.0011
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Mycobacterium leprae	Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE)	0.1135	1	1
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0092	0.0741	0.0731
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Trypanosoma cruzi	cysteine peptidase, putative	0.0014	0.0044	0.0047
Trypanosoma cruzi	cysteine protease, putative	0.0014	0.0044	0.0047
Plasmodium vivax	adenosine/AMP deaminase, putative	0.1061	0.9344	0.9344
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.016	0.015
Loa Loa (eye worm)	hypoxia-induced factor 1	0.012	0.0988	0.0988
Onchocerca volvulus		0.0027	0.016	0.015
Trypanosoma cruzi	AMP deaminase, putative	0.1061	0.9344	1
Loa Loa (eye worm)	hypothetical protein	0.0558	0.4874	0.4874
Trypanosoma brucei	AMP deaminase, putative	0.1061	0.9344	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Onchocerca volvulus	AMP deaminase 2 homolog	0.1061	0.9344	0.9343
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Leishmania major	adenine aminohydrolase	0.1135	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.016	0.0172
Entamoeba histolytica	cysteine proteinase, putative	0.0018	0.0081	0.0037
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.016	0.015
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Loa Loa (eye worm)	hypothetical protein	0.0577	0.5047	0.5047
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Onchocerca volvulus		0.0027	0.016	0.015
Brugia malayi	hypothetical protein	0.013	0.1078	0.1078
Trypanosoma cruzi	AMP deaminase, putative	0.1061	0.9344	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Trichomonas vaginalis	adenosine deaminase, putative	0.1135	1	1
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Loa Loa (eye worm)	acetylcholinesterase 1	0.0547	0.4776	0.4776
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Echinococcus granulosus	AMP deaminase 2	0.1061	0.9344	0.9343
Leishmania major	hypothetical protein, conserved	0.0558	0.4874	0.4869
Trypanosoma brucei	AMP deaminase, putative	0.1061	0.9344	1
Loa Loa (eye worm)	hypothetical protein	0.0577	0.5047	0.5047
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0027	0.016	0.0117
Mycobacterium ulcerans	carboxylesterase, LipT	0.0092	0.0741	0.0575
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Brugia malayi	Carboxylesterase family protein	0.0092	0.0741	0.0741
Loa Loa (eye worm)	aryl Hydrocarbon receptor Associated protein family member	0.001	0.001	0.001
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0014	0.0044	0.0047
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Mycobacterium ulcerans	adenosine deaminase	0.1135	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Onchocerca volvulus		0.0092	0.0741	0.0731
Brugia malayi	Carboxylesterase family protein	0.0092	0.0741	0.0741
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.016	0.016
Loa Loa (eye worm)	hypothetical protein	0.0547	0.4776	0.4776
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0741	0.0741
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0092	0.0741	0.0731
Mycobacterium tuberculosis	Probable adenosine deaminase Add (adenosine aminohydrolase)	0.1135	1	1
Loa Loa (eye worm)	hypothetical protein	0.1135	1	1
Chlamydia trachomatis	two component regulatory system sensor histidine kinase	0.001	0.001	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Echinococcus granulosus	acetylcholinesterase	0.0547	0.4776	0.4771
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.1135	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Toxoplasma gondii	AMP deaminase	0.1061	0.9344	0.9333
Echinococcus multilocularis	cysteine protease	0.0027	0.016	0.015
Schistosoma mansoni	eukaryotic elongation factor 2 kinase (eef-2 kinase)	0.0019	0.009	0.009
Entamoeba histolytica	cysteine proteinase, putative	0.0027	0.016	0.0117
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0027	0.016	0.015
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Schistosoma mansoni	family A2 unassigned peptidase (A02 family)	0.0022	0.0112	0.0112
Brugia malayi	MHCK/EF2 kinase domain family protein	0.0019	0.009	0.009
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Schistosoma mansoni	cathepsin F (C01 family)	0.0018	0.0081	0.0081
Trichomonas vaginalis	spcc417.12 protein, putative	0.0092	0.0741	0.0731
Schistosoma mansoni	adenosine deaminase-related	0.1135	1	1
Brugia malayi	Carboxylesterase family protein	0.0092	0.0741	0.0741
Onchocerca volvulus		0.0092	0.0741	0.0731
Leishmania major	AMP deaminase, putative,amp deaminase-like protein	0.1061	0.9344	0.9343
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.016	0.016
Trypanosoma brucei	RNA helicase, putative	0.0068	0.0524	0.0516
Echinococcus multilocularis	transfer RNA-Lys	0.0029	0.0176	0.0166
Loa Loa (eye worm)	fibroinase	0.0027	0.016	0.016
Echinococcus multilocularis	acetylcholinesterase	0.0547	0.4776	0.4771
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Brugia malayi	Papain family cysteine protease containing protein	0.0014	0.0044	0.0044
Trypanosoma brucei	myosin heavy chain kinase A, putative	0.0019	0.009	0.005
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0014	0.0044	0.0044
Echinococcus granulosus	eukaryotic elongation factor 2 kinase	0.0019	0.009	0.008
Plasmodium vivax	adenosine deaminase, putative	0.1135	1	1
Entamoeba histolytica	adenosine deaminase, putative	0.1135	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.016	0.015
Brugia malayi	hypoxia-induced factor 1	0.012	0.0988	0.0988
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Schistosoma mansoni	aryl hydrocarbon receptor	0.0039	0.0266	0.0266
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Trypanosoma cruzi	cruzipain precursor, putative	0.0027	0.016	0.0172
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0027	0.016	0.0117
Schistosoma mansoni	gliotactin	0.0092	0.0741	0.0741
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0081	0.0081
Onchocerca volvulus		0.0018	0.0081	0.0071
Loa Loa (eye worm)	hypothetical protein	0.0577	0.5047	0.5047
Trichomonas vaginalis	adenosine deaminase, putative	0.1135	1	1
Brugia malayi	Cathepsin L-like precursor	0.0027	0.016	0.016
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.016	0.015
Echinococcus granulosus	single minded 2	0.0029	0.0176	0.0166
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.016	0.0125
Brugia malayi	adenosine monophosphate deaminase	0.1061	0.9344	0.9344
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.0092	0.0741	0.0731
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.016	0.015
Trypanosoma cruzi	cysteine proteinase, putative	0.0014	0.0044	0.0047
Leishmania major	cathepsin L-like protease	0.0027	0.016	0.015
Plasmodium vivax	vivapain-2	0.0027	0.016	0.016
Trypanosoma cruzi	STE group serine/threonine-protein kinase, putative	0.001	0.0012	0.0013
Loa Loa (eye worm)	ctsf protein	0.0027	0.016	0.016
Echinococcus multilocularis	cathepsin L	0.0014	0.0044	0.0034

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 1.2 uM	Inhibitory activity against recombinant human Cathepsin K	ChEMBL.	16380250
IC50 (binding)	= 1.2 uM	Inhibitory activity against recombinant human Cathepsin K	ChEMBL.	16380250

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 354517