Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.5502 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.5502 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.5502 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.5502 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.5502 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3488 | 0.3049 | 0.3049 |
Trypanosoma brucei | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3488 | 0.3049 | 0.3049 |
Entamoeba histolytica | adenosine deaminase, putative | 0.5502 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.5502 | 1 | 1 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.2605 | 0 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.5502 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.2605 | 0 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.5502 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.5502 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.5502 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.5502 | 1 | 1 |
Mycobacterium ulcerans | adenosine deaminase | 0.5502 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.2605 | 0 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.2605 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3488 | 0.3049 | 0.3049 |
Plasmodium falciparum | adenosine deaminase | 0.5502 | 1 | 1 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.5502 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.5502 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.5502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3488 | 0.3049 | 0.3049 |
Echinococcus multilocularis | adenosine deaminase | 0.5502 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.5502 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 100 uM | Antifungal activity against Penicillium chrysogenum IFO 4626 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Saccharomyces cerevisiae X2180 1A | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Saccharomyces cerevisiae IFO 0203 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Schizosaccharomyces pombe IFO 0342 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Schizosaccharomyces pombe L972 h- | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Schizosaccharomyces pombe SA21 h+ | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Candida albicans IFO 1061 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Rhodotorula mucilaginosa IFO 0001 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antifungal activity against Aspergillus niger ATCC 6275 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antifungal activity against Mucor mucedo IFO 7684 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antifungal activity against Rhizopus oryzae IFO 4766 | ChEMBL. | 16403624 |
MIC (functional) | = 400 uM | Antibacterial activity against Escherichia coli IFO 2545 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antibacterial activity against Bacillus subtilis IFO 3007 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antibacterial activity against Micrococcus luteus IFO 3333 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Saccharomyces cerevisiae X2180 1A | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Saccharomyces cerevisiae IFO 0203 | ChEMBL. | 16403624 |
MIC (functional) | > 400 uM | Antimicrobial activity against Candida albicans IFO 1061 | ChEMBL. | 16403624 |
MIC (functional) | = 400 uM | Antibacterial activity against Escherichia coli IFO 2545 | ChEMBL. | 16403624 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.