Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0059 | 0.0044 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0593 | 0.0578 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Entamoeba histolytica | thymidine kinase, putative | 0.0245 | 0.5071 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1794 | 0.1781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.1341 | 0.2644 |
Echinococcus granulosus | sex peptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptide Y receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.001 | 0.0042 | 0.0027 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0245 | 0.5071 | 0.6497 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0071 | 0.1347 | 0.2657 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.007 | 0.1341 | 0.1449 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0245 | 0.5071 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.1341 | 0.2644 |
Echinococcus multilocularis | serotonin receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | thymidine kinase | 0.0314 | 0.6546 | 0.6541 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptides capa receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0632 | 0.0617 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0999 | 0.1068 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0593 | 0.0578 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0206 | 0.019 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0042 | 0.0027 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0362 | 0.7573 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.9003 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0362 | 0.7573 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.7573 | 0.8404 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0245 | 0.5071 | 0.6497 |
Echinococcus multilocularis | somatostatin receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.001 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0999 | 0.1068 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0206 | 0.019 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0071 | 0.1347 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptide Y receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | thymidine kinase | 0.0314 | 0.6546 | 0.6541 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Giardia lamblia | CDC8 | 0.0071 | 0.1347 | 0.0017 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0206 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0632 | 0.0658 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | thymidylate kinase | 0.0071 | 0.1347 | 0.1334 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.1794 | 0.1955 |
Echinococcus granulosus | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | fmrfamide receptor | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.007 | 0.1341 | 0.1725 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | allatostatin A receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0552 | 0.0537 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.1341 | 0.2644 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0999 | 0.127 |
Plasmodium vivax | thymidylate kinase, putative | 0.0071 | 0.1347 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0593 | 0.0578 |
Loa Loa (eye worm) | thymidylate kinase | 0.0071 | 0.1347 | 0.1457 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0245 | 0.5071 | 1 |
Echinococcus granulosus | serotonin receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1794 | 0.1781 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1794 | 0.1781 |
Brugia malayi | thymidylate kinase | 0.0071 | 0.1347 | 0.1733 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0552 | 0.0677 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.9003 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1794 | 0.1781 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0206 | 0.0182 |
Echinococcus granulosus | thymidine kinase | 0.0314 | 0.6546 | 0.6541 |
Echinococcus multilocularis | thymidine kinase | 0.0314 | 0.6546 | 0.6541 |
Echinococcus multilocularis | fmrfamide receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | transfer RNA-Ile | 0.0314 | 0.6546 | 0.6541 |
Schistosoma mansoni | thymidine kinase | 0.0314 | 0.6546 | 0.6541 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0056 | 0.0019 |
Echinococcus granulosus | hypothetical protein | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.1341 | 0.2644 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.001 | 0.0042 | 0.0027 |
Mycobacterium ulcerans | thymidylate kinase | 0.0071 | 0.1347 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0071 | 0.1347 | 0.1284 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1347 | 0.1334 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.1352 | 0.1338 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | thymidylate kinase | 0.0071 | 0.1347 | 0.1334 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0362 | 0.7573 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0206 | 0.019 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0206 | 0.019 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0206 | 0.019 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0059 | 0.0019 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | serotonin receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0206 | 0.0182 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Chlamydia trachomatis | thymidylate kinase | 0.0071 | 0.1347 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0071 | 0.1347 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0552 | 0.0569 |
Schistosoma mansoni | adenoreceptor | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0999 | 0.127 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.001 | 0.0042 | 0.0027 |
Trypanosoma brucei | thymidine kinase | 0.0245 | 0.5071 | 0.5981 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.1341 | 0.2644 |
Leishmania major | thymidine kinase, putative | 0.0245 | 0.5071 | 0.6497 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.007 | 0.1341 | 0.1327 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0071 | 0.1347 | 0.5 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.001 | 0.0042 | 0.0027 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0071 | 0.1347 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0206 | 0.019 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0206 | 0.019 |
Echinococcus granulosus | g-protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1794 | 0.1781 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | allatostatin A receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0206 | 0.019 |
Echinococcus multilocularis | sex peptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | fmrfamide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0071 | 0.1347 | 0.1284 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | myosin xvIII | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0362 | 0.7573 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | histamine h1 receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0071 | 0.1347 | 0.2657 |
Echinococcus granulosus | neuropeptide s receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0245 | 0.5071 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | neuropeptide s receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.1794 | 0.2326 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1794 | 0.1781 |
Echinococcus multilocularis | orexin receptor type 2 | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | thymidylate kinase | 0.0071 | 0.1347 | 0.1334 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Plasmodium falciparum | thymidylate kinase | 0.0071 | 0.1347 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | g-protein coupled receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0206 | 0.019 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0059 | 0.0044 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.0314 | 0.6546 | 0.6541 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0206 | 0.0217 |
Giardia lamblia | Thymidine kinase | 0.0245 | 0.5071 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | neuropeptides capa receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1794 | 0.1781 |
Toxoplasma gondii | thymidylate kinase | 0.0071 | 0.1347 | 1 |
Leishmania major | thymidylate kinase-like protein | 0.0071 | 0.1347 | 0.1284 |
Echinococcus multilocularis | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0071 | 0.1347 | 0.5 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0071 | 0.1347 | 0.0017 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.3792 | 0.4184 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0632 | 0.0783 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0593 | 0.0578 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | thymidylate kinase | 0.0071 | 0.1347 | 0.1334 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.007 | 0.1341 | 0.1327 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0042 | 0.0027 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0206 | 0.0217 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0475 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0042 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.001 | 0.0042 | 0.0027 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.001 | 0.0042 | 0.0027 |
Onchocerca volvulus | 0.0033 | 0.0552 | 0.3905 | |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.007 | 0.1341 | 0.1327 |
Echinococcus granulosus | orexin receptor type 2 | 0.001 | 0.0042 | 0.0027 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED 50 (functional) | = 0.08 uM | In Vitro evaluation of the compound for the antiproliferative activity by observing the growth inhibition of L1210 lymphoid leukemia cells in culture at 72 hour | ChEMBL. | 7452687 |
ILS (functional) | = 6 % | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 100 mg/kg/day x 5 was determined as percentage increase in the life span as compared with control tumor bearers | ChEMBL. | 7452687 |
ILS (functional) | = 28 % | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 25 mg/kg/day x 5 was determined as percentage increase in the life span as compared with control tumor bearers | ChEMBL. | 7452687 |
ILS (functional) | = 50 % | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 50 mg/kg/day x 5 was determined as percentage increase in the life span as compared with control tumor bearers | ChEMBL. | 7452687 |
Survival time (functional) | = 7 day | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 25 mg/kg/day x 5 was determined as Survival time in days; Range is 7-15 days | ChEMBL. | 7452687 |
Survival time (functional) | = 8 day | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 100 mg/kg/day x 5 was determined as Survival time in days; Range is 8-13 days | ChEMBL. | 7452687 |
Survival time (functional) | = 10 day | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 50 mg/kg/day x 5 was determined as Survival time in days; Range is 10-17 days | ChEMBL. | 7452687 |
Survivors (functional) | = 0 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 25 mg/kg/day x 5 was determined and number of animals survived on 30 th day were reported; 0/8 | ChEMBL. | 7452687 |
Survivors (functional) | = 0 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 50 mg/kg/day x 5 was determined and number of animals survived on 30 th day were reported; 0/8 | ChEMBL. | 7452687 |
Survivors (functional) | = 0 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 100 mg/kg/day x 5 was determined and number of animals survived on 30 th day were reported; 0/8 | ChEMBL. | 7452687 |
T/C (functional) | = 9.5 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose of 100 mg/kg/day x 5 was determined as mean survival of treated group compared to untreated; 9.5/9 | ChEMBL. | 7452687 |
T/C (functional) | = 11.5 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose of 25 mg/kg/day x 5 was determined as mean survival of treated group compared to untreated; 11.5/9 | ChEMBL. | 7452687 |
T/C (functional) | = 13.5 | Antitumor activity in the mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose of 50 mg/kg/day x 5 was determined as mean survival of treated group compared to untreated; 13.5/9 | ChEMBL. | 7452687 |
Weight change (functional) | = -2.02 g mouse-1 | Antitumor activity in mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 100 mg/kg/day x 5 was determined as weight change (g/mouse) on 8th day | ChEMBL. | 7452687 |
Weight change (functional) | = -1.25 g mouse-1 | Antitumor activity in mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 25 mg/kg/day x 5 was determined as weight change (g/mouse) on 8th day | ChEMBL. | 7452687 |
Weight change (functional) | = -1.05 g mouse-1 | Antitumor activity in mice with intraperitoneal implanted L1210 lymphoid leukemia at the dose 50 mg/kg/day x 5 was determined as weight change (g/mouse) on 8th day | ChEMBL. | 7452687 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.