Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | nuclear receptor RXR | 0.0019 | 0.0025 | 0.0025 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1789 | 1 | 1 |
Onchocerca volvulus | 0.0017 | 0.0014 | 0.0055 | |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | thymidylate synthase | 0.0466 | 0.2543 | 0.2543 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0511 | 0.0511 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0019 | 0.0028 | 0.0028 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0344 | 0.1859 | 0.1859 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1789 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0656 | 0.3613 | 0.3598 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.074 | 0.074 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.1789 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.074 | 0.074 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0036 | 0.012 | 0.012 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.1789 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0103 | 0.05 | 0.05 |
Brugia malayi | dihydrofolate reductase family protein | 0.019 | 0.0989 | 0.0989 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0094 | 0.0094 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.1789 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0017 | 0.0014 | 0.0014 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1789 | 1 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0085 | 0.0062 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0085 | 0.0062 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0097 | 0.0097 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0036 | 0.012 | 0.0472 |
Echinococcus multilocularis | dihydrofolate reductase | 0.019 | 0.0989 | 0.0989 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0069 | 0.0069 |
Onchocerca volvulus | 0.0466 | 0.2543 | 1 | |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0069 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0123 | 0.0611 | 0.0611 |
Schistosoma mansoni | hypothetical protein | 0.0573 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.074 | 0.074 |
Echinococcus granulosus | dihydrofolate reductase | 0.019 | 0.0989 | 0.0989 |
Schistosoma mansoni | coup transcription factor | 0.0036 | 0.012 | 0.012 |
Brugia malayi | MH2 domain containing protein | 0.039 | 0.212 | 0.212 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0069 | 0.0069 |
Onchocerca volvulus | 0.0017 | 0.0014 | 0.0055 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0097 | 0.0097 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0185 | 0.0185 |
Echinococcus multilocularis | thymidylate synthase | 0.0466 | 0.2543 | 0.2543 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.0178 | 0.0178 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0156 | 0.08 | 0.08 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.1789 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1789 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0036 | 0.012 | 0.012 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.1789 | 1 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | tar DNA binding protein | 0.013 | 0.0654 | 0.0654 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0186 | 0.0965 | 0.0965 |
Brugia malayi | conserved hypotetical protein | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0144 | 0.0144 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | nuclear hormone receptor | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1107 | 0.6158 | 0.6158 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | acetyltransferase | 0.0156 | 0.08 | 0.08 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | RNA recognition motif domain containing protein | 0.013 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0144 | 0.0144 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0085 | 0.0085 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0185 | 0.0185 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1789 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.014 | 0.071 | 0.0689 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0118 | 0.0118 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.074 | 0.074 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0105 | 0.0105 |
Schistosoma mansoni | nuclear receptor | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1107 | 0.6158 | 0.6158 |
Echinococcus granulosus | thymidylate synthase | 0.0466 | 0.2543 | 0.2543 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0023 | 0.0023 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.074 | 0.074 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Onchocerca volvulus | 0.0047 | 0.0185 | 0.0726 | |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.0654 | 0.0654 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0118 | 0.0118 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Chlamydia trachomatis | dihydrofolate reductase | 0.019 | 0.0989 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0036 | 0.012 | 0.012 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.0178 | 0.0156 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0062 | 0.0267 | 0.0267 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0656 | 0.3613 | 0.3598 |
Brugia malayi | nuclear receptor NHR-88 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | geminin | 0.0573 | 0.3148 | 0.3148 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0144 | 0.0144 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0069 | 0.0069 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0466 | 0.2543 | 0.1724 |
Onchocerca volvulus | 0.0036 | 0.012 | 0.0472 | |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0071 | 0.0317 | 0.0317 |
Echinococcus granulosus | adenosylhomocysteinase | 0.1789 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0097 | 0.0097 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.074 | 0.074 |
Schistosoma mansoni | dihydrofolate reductase | 0.019 | 0.0989 | 0.0989 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus granulosus | tar DNA binding protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | nuclear hormone receptor | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0105 | 0.0105 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0466 | 0.2543 | 0.2543 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0152 | 0.0775 | 0.0775 |
Schistosoma mansoni | smad | 0.0027 | 0.0069 | 0.0069 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0017 | 0.0014 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0156 | 0.08 | 0.08 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | nuclear factor I | 0.0015 | 0.0002 | 0.0002 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0221 | 0.0221 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0185 | 0.0185 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0515 | 0.282 | 0.282 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0069 | 0.0069 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0105 | 0.0511 | 0.0511 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0023 | 0.0023 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0002 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.0178 | 0.0156 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0103 | 0.05 | 0.05 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0069 | 0.0069 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Smad1 | 0.0027 | 0.0069 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0573 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0221 | 0.0221 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0071 | 0.0317 | 0.0317 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.1789 | 1 | 1 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0097 | 0.038 |
Trichomonas vaginalis | set domain proteins, putative | 0.0256 | 0.1363 | 0.1363 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0097 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0185 | 0.0185 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0515 | 0.282 | 0.282 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.074 | 0.074 |
Brugia malayi | nuclear receptor NHR-88 | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.039 | 0.212 | 0.212 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0221 | 0.0221 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0097 | 0.0074 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0221 | 0.0221 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0155 | 0.0155 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.074 | 0.074 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0023 | 0.0023 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0105 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.1789 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0105 | 0.0105 |
Brugia malayi | steroid hormone receptor | 0.0036 | 0.012 | 0.012 |
Plasmodium falciparum | adenosylhomocysteinase | 0.1789 | 1 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.0178 | 0.0178 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0105 | 0.0082 |
Loa Loa (eye worm) | TAR-binding protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0014 | 0.0014 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0085 | 0.0062 |
Brugia malayi | RNA binding protein | 0.013 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0097 | 0.0097 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.014 | 0.071 | 0.071 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.074 | 0.074 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0095 | 0.0095 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0185 | 0.0185 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0105 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0286 | 0.1532 | 0.1532 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0097 | 0.0074 |
Brugia malayi | thymidylate synthase | 0.0466 | 0.2543 | 0.2543 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0097 | 0.0074 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.0178 | 0.0156 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0344 | 0.1859 | 0.1859 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | DR-78 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0105 | 0.0105 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0185 | 0.0185 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0562 | 0.3084 | 0.3084 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0222 | 0.1168 | 0.1147 |
Brugia malayi | ecdysone receptor | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0185 | 0.0185 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0123 | 0.0611 | 0.0611 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0103 | 0.05 | 0.05 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0017 | 0.0014 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0185 | 0.0185 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0656 | 0.3613 | 0.3613 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0144 | 0.0144 |
Onchocerca volvulus | 0.0256 | 0.1363 | 0.5358 | |
Schistosoma mansoni | adenosylhomocysteinase | 0.1107 | 0.6158 | 0.6158 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0156 | 0.08 | 0.08 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.004 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.019 | 0.0989 | 0.0989 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.039 | 0.212 | 0.212 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0036 | 0.012 | 0.0472 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0185 | 0.0185 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.014 | 0.071 | 0.071 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0071 | 0.0317 | 0.0295 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0036 | 0.012 | 0.012 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0185 | 0.0185 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.1789 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.1789 | 1 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0002 | 0.0002 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0023 | 0.0023 |
Schistosoma mansoni | nuclear hormone receptor | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.071 | 0.0406 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | jumonji domain containing protein | 0.0082 | 0.038 | 0.038 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | TAR-binding protein | 0.013 | 0.0654 | 0.0654 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0036 | 0.012 | 0.012 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0097 | 0.6157 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.019 | 0.0989 | 0.0969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0222 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0023 | 0.0023 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.0178 | 0.0178 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0155 | 0.0155 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | survival motor neuron protein | 0.0105 | 0.0511 | 0.0511 |
Onchocerca volvulus | 0.0033 | 0.0105 | 0.0411 | |
Onchocerca volvulus | 0.0105 | 0.0511 | 0.2009 | |
Schistosoma mansoni | adenosylhomocysteinase | 0.1107 | 0.6158 | 0.6158 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | hypothetical protein | 0.0222 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0123 | 0.0611 | 0.0611 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0105 | 0.0105 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0221 | 0.0221 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0185 | 0.0726 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0036 | 0.012 | 0.012 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0026 | 0.0026 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0044 | 0.0166 | 0.0166 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0021 | 0.0038 | 0.0038 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0085 | 0.0085 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0036 | 0.012 | 0.012 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0042 | 0.0157 | 0.0134 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0222 | 0.1168 | 0.1168 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.0654 | 0.0654 |
Brugia malayi | nuclear receptor RXR | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.014 | 0.071 | 0.071 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0025 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.0134 | 0.0134 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0105 | 0.0105 |
Brugia malayi | nuclear receptor NHR-67 | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.0654 | 0.0654 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0466 | 0.2543 | 0.2526 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0085 | 0.0085 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | thyroid hormone receptor | 0.0036 | 0.012 | 0.012 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0656 | 0.3613 | 0.3613 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.0285 | 0.0285 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0069 | 0.0069 |
Onchocerca volvulus | 0.0031 | 0.0095 | 0.0373 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0105 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0097 | 0.0097 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0036 | 0.012 | 0.012 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0017 | 0.0014 | 0.0055 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.1789 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0017 | 0.0014 | 0.0055 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0225 | 0.1188 | 0.1188 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0123 | 0.0611 | 0.0611 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.028 | 0.0258 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0071 | 0.0317 | 0.0317 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.014 | 0.071 | 0.071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0344 | 0.1859 | 0.1859 |
Brugia malayi | Pre-SET motif family protein | 0.0225 | 0.1188 | 0.1188 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0017 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.071 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.012 | 0.012 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0656 | 0.3613 | 0.3613 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0036 | 0.012 | 0.012 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0656 | 0.3613 | 0.3598 |
Echinococcus granulosus | smad | 0.0027 | 0.0069 | 0.0069 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0221 | 0.0221 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0085 | 0.0085 |
Schistosoma mansoni | nuclear hormone receptor | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0344 | 0.1859 | 0.1859 |
Schistosoma mansoni | nuclear receptor | 0.0017 | 0.0014 | 0.0014 |
Schistosoma mansoni | thyroid hormone receptor | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0155 | 0.0155 |
Brugia malayi | hypothetical protein | 0.0515 | 0.282 | 0.282 |
Brugia malayi | ecdysteroid receptor | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0221 | 0.0221 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0123 | 0.0611 | 0.0611 |
Echinococcus granulosus | jumonji domain containing protein | 0.0044 | 0.0166 | 0.0166 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0036 | 0.012 | 0.012 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0097 | 0.0097 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0042 | 0.0157 | 0.0157 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0036 | 0.012 | 0.0472 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0036 | 0.012 | 0.012 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.014 | 0.071 | 0.0406 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0036 | 0.012 | 0.012 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0344 | 0.1859 | 0.1859 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0085 | 0.0085 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0085 | 0.0085 |
Echinococcus granulosus | geminin | 0.0573 | 0.3148 | 0.3148 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.014 | 0.071 | 0.071 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0123 | 0.0611 | 0.0611 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0036 | 0.012 | 0.012 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0085 | 0.0062 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0069 | 0.0069 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.1789 | 1 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0071 | 0.0317 | 0.0317 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0186 | 0.0965 | 0.0965 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0515 | 0.282 | 0.282 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0185 | 0.0185 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0071 | 0.0317 | 0.0317 |
Mycobacterium ulcerans | thymidylate synthase | 0.0466 | 0.2543 | 0.2299 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0036 | 0.012 | 0.012 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Dihydrofolate reductase | 0.019 | 0.0989 | 0.0989 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.019 | 0.0989 | 0.0694 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0042 | 0.0157 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.014 | 0.071 | 0.0689 |
Brugia malayi | nuclear hormone receptor | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | smad | 0.0027 | 0.0069 | 0.0069 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0036 | 0.012 | 0.012 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0123 | 0.0611 | 0.0611 |
Brugia malayi | tailless protein | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | RNA binding protein | 0.013 | 0.0654 | 0.0654 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0036 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0223 | 0.0223 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.03 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus hyicus strain ATCC 9622 | ChEMBL. | 9873483 |
MIC (functional) | = 0.125 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus aureus strain ATCC 6538 | ChEMBL. | 9873483 |
MIC (functional) | = 0.25 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus aureus strain ATCC 25923 | ChEMBL. | 9873483 |
MIC (functional) | = 0.25 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus aureus strain ATCC 29213 | ChEMBL. | 9873483 |
MIC (functional) | = 0.25 ug ml-1 | In vitro inhibitory activityin iso sensitest agar against Staphylococcus hyicus strain ATCC 9621 | ChEMBL. | 9873483 |
MIC (functional) | = 0.7 ug ml-1 | Minimum inhibitory concentration of the compound required to inhibit Staphylococcus aureus ATCC29213 cell growth | ChEMBL. | No reference |
MIC (functional) | = 1 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus intermedius strain ATCC 9503 | ChEMBL. | 9873483 |
MIC (functional) | = 2 ug ml-1 | In vitro inhibitory activity in iso sensitest agar against Staphylococcus intermedius strain ATCC 29663 | ChEMBL. | 9873483 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.