Detailed information for compound 36489

Basic information

Technical information
  • TDR Targets ID: 36489
  • Name: N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl ]naphthalen-2-yl]acetamide
  • MW: 359.4 | Formula: C17H17N3O4S
  • H donors: 2 H acceptors: 4 LogP: 2.42 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1ccc2c(c1)cccc2S(=O)(=O)Nc1onc(c1C)C
  • InChi: 1S/C17H17N3O4S/c1-10-11(2)19-24-17(10)20-25(22,23)16-6-4-5-13-9-14(18-12(3)21)7-8-15(13)16/h4-9,20H,1-3H3,(H,18,21)
  • InChiKey: LLXDCSYQXGOAPS-UHFFFAOYSA-N  

Network

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Synonyms

  • N-[5-[(3,4-dimethylisoxazol-5-yl)sulfamoyl]-2-naphthyl]acetamide
  • N-[5-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]-2-naphthyl]acetamide
  • N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-2-yl]ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Endothelin receptor ET-A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 20.1 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 21.1 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium vivax vivapain-2 0.0254 0.0352 0.0303
Echinococcus granulosus protein kinase shaggy 0.0289 0.0445 0.0398
Onchocerca volvulus 0.017 0.0133 0.0554
Echinococcus multilocularis calcium dependent protein kinase 0.0153 0.0087 0.0038
Brugia malayi Protein kinase domain containing protein 0.0657 0.1409 0.1402
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Loa Loa (eye worm) thyroid receptor interactor 0.023 0.029 0.029
Brugia malayi Kinase associated domain 1 family protein 0.0229 0.0288 0.0279
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0362 0.0636 0.0588
Loa Loa (eye worm) hypothetical protein 0.0227 0.0281 0.0281
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Echinococcus multilocularis titin 0.0182 0.0163 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0275 0.0407 0.2041
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Echinococcus multilocularis serine:threonine protein kinase N2 0.0362 0.0636 0.0589
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0237 0.0308 0.0308
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0218 0.0258 0.0249
Trypanosoma brucei protein kinase, putative 0.0205 0.0224 0.0174
Trypanosoma cruzi casein kinase, putative 0.0244 0.0327 0.0319
Loa Loa (eye worm) hypothetical protein 0.0256 0.0359 0.0359
Giardia lamblia Kinase, PLK 0.0608 0.128 0.3577
Loa Loa (eye worm) cyclin domain-containing protein 0.0793 0.1765 0.1765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0352 0.061 0.0561
Plasmodium vivax hypothetical protein, conserved 0.0159 0.0105 0.0054
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0225 0.0277 0.0227
Echinococcus multilocularis 0.0271 0.0399 0.0351
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0216 0.0662
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0159 0.0105 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0264 0.038 0.1166
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0289 0.0445 0.0375
Giardia lamblia Kinase, STE STE20 0.019 0.0186 0.003
Loa Loa (eye worm) hypothetical protein 0.0717 0.1565 0.1565
Schistosoma mansoni sodium/chloride dependent transporter 0.0233 0.0299 0.029
Schistosoma mansoni hemicentin 0.0202 0.0217 0.0208
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0358 0.0625 0.0556
Loa Loa (eye worm) TK protein kinase 0.059 0.1235 0.1235
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0159 0.0105 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0365 0.112
Brugia malayi Temporarily assigned gene name protein 59 0.0251 0.0346 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.1072 0.1064
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Leishmania major casein kinase, putative 0.0244 0.0327 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0387 0.0378
Echinococcus multilocularis expressed conserved protein 0.019 0.0184 0.0135
Entamoeba histolytica hypothetical protein 0.0275 0.0407 0.2041
Echinococcus multilocularis cathepsin L cysteine protease 0.0254 0.0352 0.0304
Leishmania major protein kinase A catalytic subunit 0.0254 0.0353 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.0548 0.1123 0.1115
Giardia lamblia Kinase, CDC7 0.0202 0.0216 0.0127
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0123 0.0009 0.0009
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0497 0.0989 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0387 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.096 0.0952
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0147 0.0073 0.0022
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0159 0.0105 0.0096
Entamoeba histolytica protein kinase, putative 0.0206 0.0227 0.1006
Leishmania major NADH dehydrogenase, putative 0.0362 0.0636 0.0567
Treponema pallidum thioredoxin reductase (trxB) 0.0362 0.0636 0.1682
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0734 0.1611 0.1611
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0482 0.0473
Toxoplasma gondii cathepsin CPL 0.0254 0.0352 0.0281
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Schistosoma mansoni nck2/grb4 0.0138 0.005 0.0041
Echinococcus multilocularis tyrosine protein kinase otk 0.0399 0.0734 0.0687
Schistosoma mansoni kinase 0.017 0.0133 0.0124
Echinococcus granulosus serine:threonine protein kinase 3 0.0577 0.12 0.1157
Toxoplasma gondii AGC kinase 0.0254 0.0353 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Loa Loa (eye worm) hypothetical protein 0.1115 0.261 0.261
Schistosoma mansoni tyrosine kinase 0.039 0.071 0.0702
Plasmodium falciparum serine/threonine protein kinase KIN 0.0176 0.0148 0.0097
Trypanosoma cruzi cruzipain precursor, putative 0.0254 0.0352 0.0344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0411 0.0402
Schistosoma mansoni tyrosine kinase 0.0409 0.0759 0.0751
Echinococcus multilocularis protein kinase shaggy 0.0289 0.0445 0.0398
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0227 0.0281 0.0281
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0312 0.0506 0.0436
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0362 0.0636 0.0589
Echinococcus multilocularis nervana 2 0.0278 0.0416 0.0369
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.019 0.0184 0.0112
Echinococcus granulosus epidermal growth factor receptor 0.0781 0.1734 0.1693
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0254 0.0352 0.0304
Schistosoma mansoni roundabout 0.0399 0.0734 0.0725
Schistosoma mansoni sodium/chloride dependent transporter 0.0159 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.1115 0.261 0.261
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0327 0.0279
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0362 0.0636 0.195
Echinococcus granulosus mitogen activated protein kinase 14 0.0358 0.0625 0.0578
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0285 0.0435 0.0388
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0515 0.1036 0.0992
Echinococcus multilocularis myosin iiia 0.019 0.0186 0.0137
Echinococcus granulosus neuroglian 0.042 0.0787 0.0741
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Plasmodium falciparum thioredoxin reductase 0.3936 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.0787 0.0779
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0285 0.0435 0.0435
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0258 0.0249
Echinococcus granulosus tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0217 0.0217
Schistosoma mansoni slit 0.0398 0.0731 0.0723
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.018 0.0553
Echinococcus granulosus casein kinase I alpha 0.0244 0.0327 0.0279
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0886 0.201 0.197
Echinococcus multilocularis cathepsin b 0.0191 0.0187 0.0138
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0362 0.0636 0.0567
Loa Loa (eye worm) AGC/PKA protein kinase 0.0254 0.0353 0.0353
Trypanosoma brucei cdc2-related kinase 3 0.0267 0.0387 0.0337
Echinococcus multilocularis down syndrome cell adhesion 0.0182 0.0163 0.0114
Loa Loa (eye worm) hypothetical protein 0.0191 0.0187 0.0187
Echinococcus multilocularis 0.0217 0.0255 0.0206
Entamoeba histolytica protein kinase, putative 0.0289 0.0445 0.2259
Echinococcus granulosus twitchin 0.0972 0.2233 0.2195
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Brugia malayi Protein kinase domain containing protein 0.1075 0.2505 0.2498
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0182 0.0165 0.0116
Toxoplasma gondii hypothetical protein 0.0159 0.0105 0.0032
Echinococcus multilocularis 0.0182 0.0163 0.0114
Brugia malayi map kinase activated protein kinase protein 2 0.0886 0.201 0.2003
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0358 0.0625 0.0625
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Onchocerca volvulus 0.0182 0.0163 0.069
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0259 0.0365 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Onchocerca volvulus Netrin receptor homolog 0.0247 0.0334 0.1471
Loa Loa (eye worm) hypothetical protein 0.1052 0.2445 0.2445
Brugia malayi Protein kinase domain containing protein 0.0488 0.0966 0.0958
Loa Loa (eye worm) SRC-1 0.0344 0.0589 0.0589
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0159 0.0105 0.0056
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0362 0.0636 0.0588
Brugia malayi basement membrane proteoglycan precursor 0.0218 0.0258 0.0249
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0362 0.0636 0.0628
Echinococcus multilocularis serine threonine protein kinase 0.0454 0.0877 0.0831
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0489 0.0969 0.0969
Echinococcus multilocularis cyclin dependent kinase 9 0.017 0.0133 0.0084
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Trypanosoma brucei protein kinase, putative 0.0289 0.0445 0.0396
Onchocerca volvulus 0.0182 0.0163 0.069
Loa Loa (eye worm) hypothetical protein 0.0202 0.0217 0.0217
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0289 0.0445 0.0445
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0202 0.0217 0.0168
Echinococcus granulosus basement membrane specific heparan sulfate 0.0218 0.0258 0.0209
Brugia malayi Sushi domain 0.0734 0.1611 0.1604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Schistosoma mansoni septate junction protein 0.0398 0.0729 0.0721
Brugia malayi putative serine/threonine kinase SADA gamma 0.0176 0.0148 0.0139
Echinococcus multilocularis serine:threonine protein kinase 38 0.0362 0.0636 0.0589
Schistosoma mansoni disulfide oxidoreductase 0.0362 0.0636 0.0628
Onchocerca volvulus Peroxidasin homolog 0.0182 0.0163 0.069
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Trypanosoma cruzi polo-like protein kinase, putative 0.0608 0.128 0.1272
Onchocerca volvulus Cathepsin L homolog 0.0254 0.0352 0.1557
Brugia malayi Cyclin, N-terminal domain containing protein 0.0793 0.1765 0.1758
Toxoplasma gondii rhoptry neck protein RON9 0.0734 0.1611 0.155
Brugia malayi serine/threonine-protein kinase plk-2 0.0608 0.128 0.1272
Schistosoma mansoni cathepsin F (C01 family) 0.0254 0.0352 0.0344
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0387 0.1187
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0362 0.0636 0.0628
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0264 0.038 0.0332
Entamoeba histolytica thioredoxin reductase, putative 0.0362 0.0636 0.3353
Echinococcus multilocularis titin 0.0276 0.0411 0.0363
Trypanosoma brucei SNF1-related protein kinases, putative 0.0176 0.0148 0.0097
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0398 0.0729 0.0721
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0551 0.1131 0.1087
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0182 0.0163 0.0154
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0227 0.0281 0.0233
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Echinococcus granulosus cathepsin L 0.0139 0.0051 0.0002
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0255 0.0355 0.0307
Schistosoma mansoni tyrosine kinase 0.0676 0.1459 0.1452
Schistosoma mansoni kinase 0.0649 0.1388 0.1381
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Echinococcus granulosus neural cadherin 0.0398 0.0729 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1364 0.3261 0.3226
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0259 0.0365 0.0317
Entamoeba histolytica disulphide oxidoreductase, putative 0.0362 0.0636 0.3353
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0825 0.1848 0.1808
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0218 0.0258 0.0209
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1364 0.3261 0.3227
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0362 0.0636 0.195
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0719 0.1571 0.1571
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1364 0.3261 0.3212
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Onchocerca volvulus Serine\/threonine kinase homolog 0.0608 0.128 0.5805
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0227 0.0281 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0167 0.0126 0.0386
Trypanosoma brucei polo-like protein kinase 0.0608 0.128 0.1235
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0238 0.0311 0.0263
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1364 0.3261 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Echinococcus multilocularis c4b binding protein beta chain 0.0734 0.1611 0.157
Loa Loa (eye worm) hypothetical protein 0.0716 0.1564 0.1564
Brugia malayi Casein kinase II, alpha chain 0.0225 0.0277 0.0268
Brugia malayi phosphoinositide-dependent protein kinase I 0.0183 0.0167 0.0158
Echinococcus granulosus casein kinase I alpha 0.0244 0.0327 0.0279
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.042 0.0787 0.0741
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0168 0.0129 0.0079
Echinococcus granulosus C type lectin domian containing protein 0.0734 0.1611 0.157
Entamoeba histolytica cysteine proteinase, putative 0.0167 0.0126 0.0428
Entamoeba histolytica protein kinase domain containing protein 0.0312 0.0506 0.2607
Trichomonas vaginalis STE family protein kinase 0.0144 0.0066 0.0202
Brugia malayi Immunoglobulin I-set domain containing protein 0.059 0.1235 0.1227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Trichomonas vaginalis glutathione reductase, putative 0.1364 0.3261 1
Brugia malayi Egg laying defective protein 4 0.019 0.0184 0.0175
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.042 0.0787 0.0741
Brugia malayi Protein kinase domain containing protein 0.0719 0.1571 0.1563
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.1052 0.2445 0.2407
Echinococcus granulosus cathepsin l1 0.0254 0.0352 0.0304
Schistosoma mansoni hypothetical protein 0.0362 0.0636 0.0628
Schistosoma mansoni slit 0.0182 0.0165 0.0156
Brugia malayi Disorganized muscle protein 1 0.0182 0.0163 0.0154
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.019 0.0186 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Echinococcus multilocularis Immunoglobulin 0.0218 0.0258 0.0209
Loa Loa (eye worm) hypothetical protein 0.1052 0.2445 0.2445
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0187 0.0177 0.0177
Schistosoma mansoni serine/threonine protein kinase 0.0654 0.14 0.1392
Onchocerca volvulus 0.0254 0.0352 0.1557
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0191 0.0187 0.0178
Onchocerca volvulus 0.0731 0.1603 0.7287
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0267 0.0387 0.0387
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.018 0.0553
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0182 0.0163 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.0787 0.0779
Treponema pallidum oxidoreductase 0.0362 0.0636 0.1682
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1112 0.26 0.2564
Loa Loa (eye worm) hypothetical protein 0.0251 0.0346 0.0346
Brugia malayi Protein kinase domain containing protein 0.0342 0.0584 0.0576
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0433 0.0823 0.0823
Echinococcus granulosus tyrosine protein kinase ABL1 0.0148 0.0074 0.0025
Loa Loa (eye worm) TK/EGFR protein kinase 0.0781 0.1734 0.1734
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Echinococcus multilocularis epidermal growth factor receptor 0.0781 0.1734 0.1693
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0362 0.0636 0.0588
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0362 0.0636 0.0589
Echinococcus multilocularis notch 0.0398 0.0729 0.0683
Echinococcus multilocularis roundabout 2 0.1136 0.2664 0.2627
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0387 0.1187
Plasmodium falciparum calcium-dependent protein kinase 3 0.0227 0.0281 0.0231
Brugia malayi Muscle positioning protein 4 0.0398 0.0729 0.0721
Echinococcus granulosus titin 0.0276 0.0411 0.0363
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0255 0.0355 0.0307
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0362 0.0636 0.0567
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0275 0.0407 0.0337
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0139 0.0051 0.0043
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0358 0.0625 0.0616
Schistosoma mansoni protein kinase 0.0976 0.2244 0.2237
Onchocerca volvulus 0.0202 0.0217 0.0936
Schistosoma mansoni protein kinase 0.0433 0.0823 0.0815
Entamoeba histolytica protein kinase, putative 0.0183 0.0167 0.0663
Loa Loa (eye worm) hypothetical protein 0.0737 0.1618 0.1618
Onchocerca volvulus 0.0734 0.1611 0.7325
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0551 0.1131 0.1131
Brugia malayi Protein kinase domain containing protein 0.0139 0.0051 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0167 0.0512
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0362 0.0636 0.0589
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Echinococcus granulosus c4b binding protein beta chain 0.0734 0.1611 0.157
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1364 0.3261 0.3255
Schistosoma mansoni tyrosine kinase 0.0471 0.0922 0.0914
Plasmodium falciparum thioredoxin reductase 0.1364 0.3261 0.3226
Schistosoma mansoni protein kinase 0.0144 0.0066 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Echinococcus granulosus protein kinase C gamma type 0.0454 0.0877 0.0831
Echinococcus multilocularis twitchin 0.0255 0.0357 0.0309
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Echinococcus granulosus nervana 2 0.0278 0.0416 0.0369
Echinococcus granulosus leucine rich repeat containing protein 4 0.0182 0.0163 0.0114
Brugia malayi notch-like transmembrane receptor 0.0398 0.0729 0.0721
Schistosoma mansoni titin 0.0182 0.0163 0.0154
Schistosoma mansoni titin 0.0182 0.0163 0.0154
Echinococcus multilocularis slit 2 protein 0.0448 0.086 0.0815
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Echinococcus granulosus nephrin 0.0202 0.0217 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Onchocerca volvulus 0.0702 0.1528 0.6941
Echinococcus granulosus serine:threonine protein kinase N2 0.0654 0.14 0.1357
Onchocerca volvulus 0.0159 0.0105 0.0423
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0276 0.0411 0.0411
Brugia malayi Variant SH3 domain containing protein 0.0138 0.005 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0362 0.0636 0.0567
Echinococcus granulosus calcium activated potassium channel 0.0303 0.0482 0.0434
Loa Loa (eye worm) hypothetical protein 0.0218 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Brugia malayi STE20-like kinase MST 0.0577 0.12 0.1193
Loa Loa (eye worm) hypothetical protein 0.1038 0.2407 0.2407
Echinococcus multilocularis tyrosine protein kinase Blk 0.028 0.0421 0.0374
Echinococcus multilocularis serine:threonine protein kinase N2 0.0654 0.14 0.1357
Echinococcus granulosus protein tyrosine kinase 0.0649 0.1387 0.1345
Schistosoma mansoni serine/threonine-protein kinase 0.0369 0.0655 0.0646
Brugia malayi Protein kinase domain containing protein 0.0148 0.0074 0.0065
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0344 0.0589 0.0542
Onchocerca volvulus 0.0254 0.0352 0.1557
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0191 0.0187 0.0178
Loa Loa (eye worm) hypothetical protein 0.0415 0.0776 0.0776
Trypanosoma cruzi casein kinase, putative 0.0244 0.0327 0.0319
Brugia malayi Animal haem peroxidase family protein 0.0182 0.0163 0.0154
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0187 0.0177 0.0104
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Schistosoma mansoni peroxidasin 0.0218 0.0259 0.0251
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0163 0.0163
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0217 0.0217
Echinococcus granulosus down syndrome cell adhesion 0.0182 0.0163 0.0114
Schistosoma mansoni sodium/chloride dependent transporter 0.0159 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0321 0.0529 0.0529
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0362 0.0636 0.0589
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0352 0.061 0.0561
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Giardia lamblia Kinase, NEK 0.0306 0.0489 0.1014
Brugia malayi SRC-1 0.0344 0.0589 0.0581
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0362 0.0636 0.3353
Loa Loa (eye worm) hypothetical protein 0.0406 0.0752 0.0752
Schistosoma mansoni serine/threonine protein kinase 0.0548 0.1123 0.1115
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.0177 0.0168
Echinococcus multilocularis roundabout 2 0.042 0.0787 0.0741
Entamoeba histolytica protein kinase , putative 0.0264 0.038 0.1887
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.0051 0.0157
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0254 0.0352 0.0303
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0218 0.0258 0.0209
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0191 0.0187 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0369 0.0654 0.0607
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0451 0.087 0.0824
Brugia malayi Protein kinase domain containing protein 0.0267 0.0387 0.0378
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1052 0.2445 0.2438
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0362 0.0636 0.0589
Brugia malayi Protein kinase domain containing protein 0.1009 0.233 0.2324
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0411 0.0402
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.0592 0.0584
Echinococcus granulosus roundabout 2 0.042 0.0787 0.0741
Giardia lamblia Kinase, CMGC GSK 0.0289 0.0445 0.0871
Brugia malayi Protein kinase domain containing protein 0.0436 0.0829 0.0821
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0497 0.0989 0.0944
Echinococcus granulosus contactin 0.042 0.0787 0.0741
Echinococcus multilocularis tyrosine kinase 0.0148 0.0074 0.0025
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1364 0.3261 0.3226
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0289 0.0445 0.0437
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0209 0.0236 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0294 0.0285
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0362 0.0636 0.0636
Echinococcus granulosus c src tyrosine kinase 0.0211 0.0241 0.0193
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0886 0.201 0.197
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.0592 0.0584
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0275 0.0407 0.0358
Schistosoma mansoni septate junction protein 0.0218 0.0258 0.0249
Schistosoma mansoni adapter molecule crk 0.0138 0.005 0.0041
Trypanosoma cruzi Protein kinase B 0.0369 0.0655 0.0646
Brugia malayi Protein kinase domain containing protein 0.0369 0.0654 0.0646
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0362 0.0636 0.0589
Plasmodium vivax thioredoxin reductase, putative 0.3936 1 1
Brugia malayi Protein kinase domain containing protein 0.0479 0.0944 0.0936
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0254 0.0353 0.0303
Loa Loa (eye worm) hypothetical protein 0.0243 0.0324 0.0324
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Plasmodium vivax tyrosine kinase-like protein, putative 0.0182 0.0164 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0654 0.0646
Onchocerca volvulus 0.0254 0.0352 0.1557
Giardia lamblia Kinase, CMGC DYRK 0.0312 0.0506 0.1068
Trichomonas vaginalis STE family protein kinase 0.0193 0.0194 0.0594
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.0944 0.0936
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.0787 0.0779
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0395 0.0723 0.0723
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0123 0.0009 0.0027
Trypanosoma cruzi casein kinase, putative 0.0244 0.0327 0.0319
Trypanosoma brucei hypothetical protein, conserved 0.0362 0.0636 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.0573 0.119 0.1182
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0362 0.0636 0.3353
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0159 0.0105 0.0056
Brugia malayi serine/threonine protein kinase 6 0.0264 0.038 0.0372
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0793 0.1765 0.1757
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.0051 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Brugia malayi hypothetical protein 0.05 0.0996 0.0988
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0254 0.0353 0.0303
Echinococcus multilocularis Immunoglobulin 0.0218 0.0258 0.0209
Onchocerca volvulus 0.0398 0.0729 0.3284
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0139 0.0051 0.0043
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Schistosoma mansoni nephrin related 0.0218 0.0258 0.0249
Trypanosoma cruzi cysteine proteinase, putative 0.0139 0.0051 0.0043
Trypanosoma brucei NADH dehydrogenase 0.0362 0.0636 0.0588
Brugia malayi Calcium binding EGF domain containing protein 0.0398 0.0729 0.0721
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0264 0.038 0.0332
Schistosoma mansoni protein kinase 0.0147 0.0073 0.0064
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1364 0.3261 1
Giardia lamblia Kinase, CMGC GSK 0.0289 0.0445 0.0871
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0218 0.0258 0.0209
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1364 0.3261 0.3227
Echinococcus multilocularis dual specificity protein kinase clk2 0.0345 0.0592 0.0545
Loa Loa (eye worm) hypothetical protein 0.0737 0.1618 0.1618
Schistosoma mansoni vav2 0.0185 0.0173 0.0165
Onchocerca volvulus 0.0159 0.0105 0.0423
Schistosoma mansoni cell adhesion molecule 0.0218 0.0258 0.0249
Echinococcus multilocularis cyclin dependent kinase 19 0.1075 0.2505 0.2468
Echinococcus granulosus Immunoglobulin 0.0218 0.0258 0.0209
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0445 0.1365
Giardia lamblia Thioredoxin reductase 0.0362 0.0636 0.1489
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0254 0.0352 0.0352
Leishmania major hypothetical protein, conserved 0.0362 0.0636 0.0567
Echinococcus multilocularis roundabout 2 0.042 0.0787 0.0741
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0254 0.0353 0.0303
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0105
Onchocerca volvulus Peroxidasin homolog 0.0182 0.0165 0.0697
Onchocerca volvulus 0.0398 0.0729 0.3284
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0176 0.0148 0.0099
Echinococcus granulosus peroxidasin 0.04 0.0735 0.0689
Brugia malayi Protein kinase domain containing protein 0.0148 0.0074 0.0065
Onchocerca volvulus 0.0182 0.0163 0.069
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Brugia malayi Fes/CIP4 homology domain containing protein 0.023 0.029 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0345 0.0592 0.0544
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1364 0.3261 0.3226
Echinococcus granulosus rho-associated protein kinase 1 0.0731 0.1603 0.1561
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0188 0.018 0.013
Schistosoma mansoni protein kinase 0.0344 0.0589 0.0581
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0362 0.0636 0.0588
Onchocerca volvulus 0.0734 0.1611 0.7325
Brugia malayi SH2 domain containing protein 0.0493 0.0978 0.097
Loa Loa (eye worm) fibroinase 0.0254 0.0352 0.0352
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0362 0.0636 0.3353
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0312 0.0506 0.0497
Echinococcus multilocularis peroxidasin 0.04 0.0735 0.0689
Loa Loa (eye worm) gastrulation defective protein 1 0.1001 0.2311 0.2311
Schistosoma mansoni serine/threonine-protein kinase 0.0369 0.0655 0.0646
Echinococcus multilocularis calcium activated potassium channel 0.0303 0.0482 0.0434
Loa Loa (eye worm) hypothetical protein 0.0716 0.1564 0.1564
Plasmodium falciparum casein kinase 2, alpha subunit 0.0225 0.0277 0.0227
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0825 0.1848 0.1808
Schistosoma mansoni tyrosine kinase 0.0472 0.0925 0.0917
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0254 0.0353 0.0303
Plasmodium falciparum calcium-dependent protein kinase 1 0.0227 0.0281 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Leishmania major protein kinase, putative 0.0345 0.0592 0.0523
Echinococcus granulosus Immunoglobulin 0.0218 0.0258 0.0209
Loa Loa (eye worm) hypothetical protein 0.0218 0.0258 0.0258
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0352 0.061 0.0602
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0166 0.0122 0.0122
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0312 0.0506 0.0457
Brugia malayi casein kinase I 0.0244 0.0327 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0407 0.0399
Brugia malayi intracellular kinase 0.0289 0.0445 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.018 0.0172
Brugia malayi Cathepsin L-like precursor 0.0167 0.0126 0.0117
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Loa Loa (eye worm) TK/EPH protein kinase 0.0257 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0188 0.018 0.0108
Plasmodium falciparum serine/threonine protein kinase, putative 0.0264 0.038 0.0331
Brugia malayi GCC2 and GCC3 family protein 0.1132 0.2653 0.2647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) cysteine protease 0.0254 0.0352 0.0352
Echinococcus multilocularis nervana 2 0.0278 0.0416 0.0369
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Loa Loa (eye worm) hypothetical protein 0.0148 0.0074 0.0074
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Brugia malayi Protein kinase domain containing protein 0.0202 0.0216 0.0207
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0105
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0362 0.0636 0.0589
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0191 0.0187 0.0178
Echinococcus granulosus tyrosine protein kinase Blk 0.028 0.0421 0.0374
Trypanosoma brucei trypanothione reductase 0.3936 1 1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0486 0.096 0.0915
Echinococcus granulosus casein kinase I gamma 0.0479 0.0944 0.0898
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0697 0.1513 0.1471
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0362 0.0636 0.0589
Leishmania major protein kinase A catalytic subunit isoform 1 0.0254 0.0353 0.0282
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Entamoeba histolytica protein kinase, putative 0.064 0.1365 0.7533
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0251 0.0346 0.0298
Onchocerca volvulus Putative cubilin 0.0398 0.0729 0.3284
Giardia lamblia Kinase, AGC AKT 0.0263 0.0377 0.0649
Echinococcus granulosus neurogenic locus notch protein 0.0398 0.0729 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Mycobacterium tuberculosis Probable oxidoreductase 0.1364 0.3261 0.2803
Brugia malayi Protein kinase domain containing protein 0.0385 0.0697 0.0688
Echinococcus multilocularis mitogen activated protein kinase 14 0.0358 0.0625 0.0578
Brugia malayi RhoGAP domain containing protein 0.0168 0.0129 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0731 0.1603 0.1596
Echinococcus multilocularis fat cadherin tumor suppressor 0.0398 0.0729 0.0683
Brugia malayi SH2 domain containing protein 0.0148 0.0074 0.0065
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0749 0.165 0.1643
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0176 0.0148 0.0076
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0227 0.0281 0.0231
Brugia malayi cathepsin L-like precursor 0.0167 0.0126 0.0117
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0281 0.0233
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0362 0.0636 0.0589
Loa Loa (eye worm) hypothetical protein 0.0934 0.2134 0.2134
Schistosoma mansoni hypothetical protein 0.0229 0.0288 0.0279
Echinococcus multilocularis Immunoglobulin subtype 0.0218 0.0258 0.0209
Onchocerca volvulus 0.0144 0.0065 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.1072 0.1064
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0256 0.0359 0.0359
Plasmodium falciparum protein serine/threonine kinase-1 0.0345 0.0592 0.0544
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0147 0.0073 0.0064
Onchocerca volvulus 0.0734 0.1611 0.7325
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0716 0.1564 0.1522
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0244 0.0327 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0357 0.0348
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0362 0.0636 0.0628
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0133 0.0124
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0522 0.1054 0.101
Schistosoma mansoni vesicular amine transporter 0.0716 0.1564 0.1556
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0254 0.0352 0.0304
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Echinococcus multilocularis tyrosine protein kinase HCK 0.0206 0.0227 0.0178
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0289 0.0445 0.0437
Brugia malayi Myb-like DNA-binding domain containing protein 0.0182 0.0163 0.0154
Onchocerca volvulus 0.0321 0.0529 0.2367
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0489 0.0969 0.0961
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0254 0.0353 0.0344
Echinococcus granulosus netrin receptor unc 5 0.0283 0.0428 0.0381
Entamoeba histolytica protein kinase, putative 0.0657 0.1409 0.779
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0193 0.0192 0.0141
Echinococcus granulosus epidermal growth factor receptor 0.0544 0.1114 0.107
Plasmodium vivax amine transporter, putative 0.0159 0.0105 0.0054
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0451 0.087 0.087
Echinococcus granulosus tyrosine kinase 0.028 0.0421 0.0374
Brugia malayi Calcium binding EGF domain containing protein 0.0398 0.0729 0.0721
Echinococcus granulosus cyclin dependent kinase 1 0.0267 0.0387 0.0339
Echinococcus multilocularis Immunoglobulin 0.0716 0.1564 0.1522
Echinococcus granulosus cyclin dependent kinase 5 0.0267 0.0387 0.0339
Echinococcus granulosus dual specificity 0.0312 0.0506 0.0459
Brugia malayi Furin-like cysteine rich region family protein 0.0781 0.1734 0.1727
Entamoeba histolytica protein kinase, putative 0.0144 0.0066 0.0083
Loa Loa (eye worm) hypothetical protein 0.0167 0.0126 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Schistosoma mansoni tyrosine kinase 0.0471 0.0922 0.0914
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0259 0.0251
Echinococcus granulosus defective proboscis extension response 0.0716 0.1564 0.1522
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0289 0.0445 0.0445
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0327 0.1003
Echinococcus granulosus notch 0.0398 0.0729 0.0683
Echinococcus granulosus geminin 0.0184 0.0169 0.012
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1009 0.233 0.233
Entamoeba histolytica cell division protein kinase 2, putative 0.0284 0.0431 0.2179
Brugia malayi serine/threonine-protein kinase 6 0.0264 0.038 0.0372
Echinococcus multilocularis NCK adaptor protein 0.014 0.0055 0.0006
Leishmania major protein kinase, putative 0.0227 0.0281 0.021
Echinococcus granulosus casein kinase I alpha 0.0244 0.0327 0.0279
Loa Loa (eye worm) animal heme peroxidase 0.0182 0.0163 0.0163
Echinococcus granulosus cathepsin l cysteine peptidase 0.0254 0.0352 0.0304
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0362 0.0636 0.3353
Echinococcus granulosus cGMP dependent protein kinase 0.019 0.0184 0.0135
Schistosoma mansoni sulfide quinone reductase 0.0362 0.0636 0.0628
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0362 0.0636 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0148 0.0139
Echinococcus granulosus tyrosine kinase 0.0148 0.0074 0.0025
Echinococcus multilocularis expressed protein 0.0187 0.0177 0.0128
Loa Loa (eye worm) TK/FAK protein kinase 0.0656 0.1405 0.1405
Echinococcus granulosus serine:threonine protein kinase 0.0256 0.0359 0.0311
Echinococcus granulosus cyclin dependent kinase 9 0.0187 0.0177 0.0128
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0217 0.0217
Echinococcus granulosus Glutaredoxin protein 5 0.0278 0.0416 0.0369
Trypanosoma brucei aurora B kinase 0.0264 0.038 0.0331
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0289 0.0445 0.0375
Brugia malayi Protein kinase domain containing protein 0.0183 0.0167 0.0158
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.064 0.1365 0.1365
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Entamoeba histolytica protein kinase, putative 0.0264 0.038 0.1887
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0275 0.0407 0.0407
Plasmodium falciparum protein kinase 5 0.0267 0.0387 0.0337
Schistosoma mansoni titin 0.0399 0.0734 0.0725
Toxoplasma gondii AGC kinase 0.064 0.1365 0.1301
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0167 0.0512
Brugia malayi Protein kinase c protein 2 0.026 0.0369 0.036
Entamoeba histolytica protein kinase 2, putative 0.0352 0.061 0.3204
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Echinococcus multilocularis dual specificity 0.0312 0.0506 0.0459
Brugia malayi hypothetical protein 0.0218 0.0258 0.0249
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0096
Entamoeba histolytica cyclin C, putative 0.0804 0.1795 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0362 0.0636 0.0588
Loa Loa (eye worm) hypothetical protein 0.0254 0.0353 0.0353
Echinococcus multilocularis casein kinase ii subunit alpha 0.0225 0.0277 0.0228
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Echinococcus granulosus casein kinase ii subunit alpha 0.0225 0.0277 0.0228
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0362 0.0636 0.0589
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0399 0.0734 0.0734
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0346 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0148 0.0139
Brugia malayi hypothetical protein 0.0251 0.0346 0.0337
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0267 0.0387 0.0339
Trypanosoma brucei protein kinase, putative 0.0147 0.0073 0.0022
Onchocerca volvulus 0.0657 0.1409 0.6399
Echinococcus granulosus activin receptor type 0.0147 0.0073 0.0023
Loa Loa (eye worm) hypothetical protein 0.0321 0.0529 0.0529
Onchocerca volvulus 0.0734 0.1611 0.7325
Echinococcus multilocularis insulin receptor 0.0676 0.1459 0.1417
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Entamoeba histolytica protein kinase domain containing protein 0.0147 0.0073 0.0123
Onchocerca volvulus 0.0734 0.1611 0.7325
Echinococcus granulosus serine:threonine kinase SAD 1 0.0176 0.0148 0.0099
Echinococcus granulosus serine:threonine protein kinase TAO1 0.05 0.0996 0.0952
Brugia malayi Cyclin C 0.1583 0.3836 0.3831
Schistosoma mansoni rap gtpase-activating protein 0.0251 0.0346 0.0337
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0251 0.0346 0.0337
Onchocerca volvulus 0.0159 0.0105 0.0423
Loa Loa (eye worm) hypothetical protein 0.0251 0.0346 0.0346
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0459 0.089 0.089
Schistosoma mansoni laminin gamma-3 chain 0.0398 0.0729 0.0721
Loa Loa (eye worm) thioredoxin reductase 0.3936 1 1
Schistosoma mansoni tyrosine kinase 0.0544 0.1114 0.1106
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.128 0.1272
Echinococcus multilocularis neurogenic locus protein delta 0.0398 0.0729 0.0683
Schistosoma mansoni protein kinase 0.0244 0.0327 0.0319
Schistosoma mansoni cell adhesion molecule 0.0182 0.0163 0.0154
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Brugia malayi serine/threonine kinase 12 0.0264 0.038 0.0372
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0032
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.028 0.0421 0.0351
Echinococcus granulosus roundabout 2 0.042 0.0787 0.0741
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0227 0.0281 0.0231
Entamoeba histolytica protein kinase domain containing protein 0.0225 0.0277 0.1293
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0327 0.1003
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Brugia malayi Leucine Rich Repeat family protein 0.0182 0.0165 0.0156
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1364 0.3261 0.3226
Schistosoma mansoni hypothetical protein 0.0202 0.0217 0.0208
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Loa Loa (eye worm) hypothetical protein 0.0229 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0184 0.0175
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0281 0.0233
Trichomonas vaginalis CMGC family protein kinase 0.0345 0.0592 0.1816
Schistosoma mansoni serine/threonine protein kinase 0.0456 0.0881 0.0873
Giardia lamblia Kinase, NEK 0.0306 0.0489 0.1014
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1364 0.3261 0.3255
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Loa Loa (eye worm) hypothetical protein 0.0201 0.0214 0.0214
Echinococcus multilocularis C type lectin domian containing protein 0.0734 0.1611 0.157
Echinococcus granulosus tyrosine protein kinase otk 0.0399 0.0734 0.0687
Onchocerca volvulus 0.0202 0.0216 0.0932
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0168 0.0129 0.0079
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0267 0.0387 0.0316
Schistosoma mansoni netrin receptor unc5 0.0218 0.0258 0.0249
Plasmodium falciparum apical sushi protein 0.0734 0.1611 0.1568
Onchocerca volvulus 0.0167 0.0126 0.0519
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0362 0.0636 0.0589
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0254 0.0352 0.0303
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0344 0.0589 0.0542
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1364 0.3261 1
Schistosoma mansoni vam6/vps39 related 0.0251 0.0346 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0264 0.038 0.1166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0188 0.018 0.0172
Leishmania major protein kinase, putative 0.019 0.0186 0.0114
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0346 0.0337
Schistosoma mansoni netrin receptor unc5 0.0283 0.0428 0.042
Echinococcus multilocularis N chimaerin 0.0168 0.0129 0.0079
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0264 0.038 0.1887
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0148 0.0074 0.0129
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Toxoplasma gondii EGF family domain-containing protein 0.0398 0.0729 0.0661
Entamoeba histolytica protein kinase domain containing protein 0.0456 0.0881 0.4759
Loa Loa (eye worm) hypothetical protein 0.0251 0.0346 0.0346
Entamoeba histolytica protein kinase, putative 0.0264 0.038 0.1887
Entamoeba histolytica casein kinase, putative 0.0244 0.0327 0.1582
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Loa Loa (eye worm) TK protein kinase 0.028 0.0421 0.0421
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0551 0.1131 0.1087
Loa Loa (eye worm) hypothetical protein 0.0202 0.0217 0.0217
Brugia malayi Cadherin domain containing protein 0.0398 0.0729 0.0721
Echinococcus multilocularis hemicentin 1 0.0399 0.0734 0.0687
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0409 0.0759 0.0713
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0218 0.0258 0.0249
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0148 0.0076 0.014
Echinococcus multilocularis neurogenic locus notch protein 0.0398 0.0729 0.0683
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0159 0.0105 0.0056
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0362 0.0636 0.1489
Loa Loa (eye worm) hypothetical protein 0.0817 0.1827 0.1827
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0362 0.0636 0.0628
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Brugia malayi Thioredoxin reductase 0.3936 1 1
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0186 0.0177
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0398 0.0729 0.0721
Brugia malayi Peroxidasin 0.04 0.0735 0.0727
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Loa Loa (eye worm) hypothetical protein 0.0312 0.0505 0.0505
Echinococcus granulosus low density lipoprotein receptor ldl 0.0218 0.0258 0.0209
Echinococcus multilocularis protein kinase c iota type 0.0642 0.1371 0.1328
Echinococcus granulosus cGMP dependent protein kinase 1 0.019 0.0184 0.0135
Echinococcus multilocularis tyrosine protein kinase Srms 0.028 0.0421 0.0374
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0362 0.0636 0.0589
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0251 0.0346 0.0337
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0147 0.0073 0.0064
Loa Loa (eye worm) TK/ALK protein kinase 0.0342 0.0584 0.0584
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Echinococcus granulosus tyrosine protein kinase 0.0346 0.0594 0.0547
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Schistosoma mansoni cell adhesion molecule 0.0202 0.0217 0.0208
Echinococcus granulosus serine:threonine protein kinase N2 0.0292 0.0451 0.0404
Schistosoma mansoni protein kinase 0.0976 0.2244 0.2237
Echinococcus multilocularis casein kinase I gamma 0.0479 0.0944 0.0898
Schistosoma mansoni protein kinase 0.0497 0.0989 0.0981
Echinococcus granulosus cyclin dependent kinase 19 0.1075 0.2505 0.2468
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Brugia malayi glutamate synthase 0.0362 0.0636 0.0628
Giardia lamblia NADH oxidase lateral transfer candidate 0.1364 0.3261 1
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0344 0.0589 0.0589
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0793 0.1765 0.1765
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0176 0.0148 0.0139
Loa Loa (eye worm) hypothetical protein 0.0419 0.0786 0.0786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0362 0.0636 0.0628
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0793 0.1765 0.1724
Loa Loa (eye worm) TK protein kinase 0.0346 0.0594 0.0594
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Trypanosoma cruzi casein kinase, putative 0.0244 0.0327 0.0319
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0312 0.0506 0.0497
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0486 0.096 0.0915
Brugia malayi Doublecortin family protein 0.0339 0.0576 0.0567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0211 0.0241 0.0233
Schistosoma mansoni nephrin 0.0918 0.2093 0.2086
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0244 0.0327 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0148 0.0139
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0188 0.018 0.0108
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0368 0.0652 0.0652
Echinococcus granulosus hemicentin 1 0.0399 0.0734 0.0687
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.028 0.0421 0.0374
Loa Loa (eye worm) AGC/PKN protein kinase 0.0654 0.14 0.14
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.0886 0.201 0.2003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0218 0.0258 0.0209
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0267 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Schistosoma mansoni sulfide quinone reductase 0.0362 0.0636 0.0628
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0369 0.0654 0.0607
Loa Loa (eye worm) hypothetical protein 0.0546 0.1119 0.1119
Loa Loa (eye worm) cyclin C 0.1583 0.3836 0.3836
Echinococcus granulosus delta-like protein 1 0.0398 0.0729 0.0683
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0176 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0719 0.1571 0.1571
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0218 0.0258 0.0249
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0493 0.0978 0.0933
Loa Loa (eye worm) hypothetical protein 0.0362 0.0636 0.0636
Trichomonas vaginalis STE family protein kinase 0.0193 0.0194 0.0594
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1364 0.3261 0.3212
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Echinococcus multilocularis netrin receptor unc 5 0.0283 0.0428 0.0381
Loa Loa (eye worm) hypothetical protein 0.0218 0.0258 0.0258
Echinococcus granulosus Immunoglobulin subtype 0.0218 0.0258 0.0209
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0522 0.1055 0.1055
Trypanosoma cruzi casein kinase II, putative 0.0225 0.0277 0.0268
Echinococcus multilocularis activin receptor type 0.0147 0.0073 0.0023
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0451 0.087 0.0824
Schistosoma mansoni hypothetical protein 0.0229 0.0288 0.0279
Schistosoma mansoni cathepsin F (C01 family) 0.0167 0.0126 0.0117
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.042 0.0787 0.0787
Echinococcus multilocularis Immunoglobulin 0.0716 0.1564 0.1522
Brugia malayi protein-tyrosine kinase 0.028 0.0421 0.0413
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0183 0.0167 0.0118
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.0194 0.0145
Echinococcus granulosus insulin receptor 0.0676 0.1459 0.1417
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0218 0.0258 0.0249
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Schistosoma mansoni serine/threonine kinase 0.0505 0.101 0.1002
Onchocerca volvulus 0.0312 0.0505 0.2258
Loa Loa (eye worm) AGC/PKA protein kinase 0.0254 0.0353 0.0353
Schistosoma mansoni tyrosine kinase 0.0676 0.1459 0.1452
Loa Loa (eye worm) solute carrier family 6 member 4 0.0159 0.0105 0.0105
Loa Loa (eye worm) AGC/AKT protein kinase 0.0657 0.1409 0.1409
Brugia malayi Delta serrate ligand family protein 0.0398 0.0729 0.0721
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1052 0.2445 0.2438
Entamoeba histolytica cysteine proteinase, putative 0.0254 0.0352 0.1726
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1364 0.3261 1
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Echinococcus multilocularis protein jagged 1 0.0398 0.0729 0.0683
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1364 0.3261 0.3255
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0176 0.0148 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0793 0.1765 0.1757
Entamoeba histolytica protein kinase, putative 0.0187 0.0177 0.0718
Entamoeba histolytica protein kinase, putative 0.0275 0.0407 0.2041
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0191 0.0187 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Echinococcus granulosus thioredoxin glutathione reductase 0.3936 1 1
Schistosoma mansoni c4b-binding protein beta chain 0.0734 0.1611 0.1604
Trichomonas vaginalis CAMK family protein kinase 0.0625 0.1324 0.406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) hypothetical protein 0.0167 0.0126 0.0126
Schistosoma mansoni tyrosine kinase 0.0781 0.1734 0.1727
Trypanosoma cruzi aurora B kinase, putative 0.0264 0.038 0.0372
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0409 0.0759 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0177 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Schistosoma mansoni protein kinase C mu 0.0489 0.0969 0.0961
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0325 0.054 0.0493
Entamoeba histolytica protein kinase, putative 0.0227 0.0281 0.1318
Echinococcus granulosus ephrin type A receptor 4 A 0.0217 0.0256 0.0208
Echinococcus multilocularis tyrosine protein kinase Abl 0.0211 0.0241 0.0193
Loa Loa (eye worm) one IG domain family member 0.0182 0.0163 0.0163
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0488 0.0966 0.0966
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0138 0.005 0.005
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0176 0.0148 0.0076
Onchocerca volvulus 0.0398 0.0729 0.3284
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Echinococcus granulosus protein kinase c iota type 0.0642 0.1371 0.1328
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Chlamydia trachomatis thioredoxin reductase 0.0362 0.0636 0.1682
Brugia malayi Protein kinase domain containing protein 0.0676 0.1459 0.1452
Trichomonas vaginalis AGC family protein kinase 0.0264 0.038 0.1166
Echinococcus granulosus serine threonine protein kinase nrc 0.0352 0.061 0.0563
Trichomonas vaginalis AGC family protein kinase 0.0264 0.038 0.1166
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Schistosoma mansoni protein kinase 0.0976 0.2244 0.2237
Brugia malayi P38 map kinase family protein 2 0.0358 0.0625 0.0616
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0327 0.1003
Schistosoma mansoni growth factor receptor-bound protein 0.0138 0.005 0.0041
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0182 0.0163 0.0114
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1364 0.3261 0.3212
Entamoeba histolytica protein kinase, putative 0.0229 0.0289 0.1361
Trichomonas vaginalis AGC family protein kinase 0.0379 0.068 0.2085
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0311 0.0503 0.1542
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0096
Echinococcus granulosus cyclin dependent kinase 9 0.017 0.0133 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0254 0.0353 0.0344
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0362 0.0636 0.0589
Echinococcus multilocularis fibropellin Ia 0.0398 0.0729 0.0683
Trypanosoma brucei casein kinase I, isoform 2 0.0244 0.0327 0.0277
Loa Loa (eye worm) serotonin transporter b 0.0159 0.0105 0.0105
Plasmodium vivax protein kinase Crk2 0.0267 0.0387 0.0337
Echinococcus granulosus cathepsin L cysteine protease 0.0139 0.0051 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0167 0.0126 0.0386
Trypanosoma cruzi NADH dehydrogenase, putative 0.0362 0.0636 0.0628
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0327 0.0319
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.0194 0.0145
Loa Loa (eye worm) notch protein 0.0398 0.0729 0.0729
Schistosoma mansoni titin 0.0202 0.0217 0.0208
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0399 0.0734 0.3303
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1641 0.3987 0.3957
Echinococcus multilocularis cyclin dependent kinase 5 0.0267 0.0387 0.0339
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Trypanosoma cruzi cdc2-related kinase 3 0.0267 0.0387 0.0378
Onchocerca volvulus 0.0148 0.0074 0.0281
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0193 0.0194 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0126 0.0117
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0159 0.0105 0.0056
Echinococcus granulosus titin 0.0182 0.0163 0.0114
Echinococcus granulosus mitogen activated protein kinase 0.0188 0.018 0.0131
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0362 0.0636 0.0628
Echinococcus multilocularis neurogenic locus protein delta 0.0398 0.0729 0.0683
Brugia malayi Cathepsin L-like cysteine proteinase 0.0167 0.0126 0.0117
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0163 0.0163
Giardia lamblia Glutamate synthase 0.0362 0.0636 0.1489
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.018 0.0159 0.011
Echinococcus multilocularis protein tyrosine kinase 0.0649 0.1387 0.1345
Echinococcus granulosus roundabout 2 0.1136 0.2664 0.2627
Brugia malayi Cam kinase protein 1 0.0227 0.0281 0.0273
Onchocerca volvulus 0.0182 0.0163 0.069
Echinococcus granulosus tyrosine protein kinase Srms 0.0611 0.1289 0.1246
Trypanosoma cruzi cysteine proteinase, putative 0.0139 0.0051 0.0043
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Schistosoma mansoni protein kinase 0.0825 0.1848 0.1841
Leishmania major protein kinase, putative 0.0264 0.038 0.031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Loa Loa (eye worm) hypothetical protein 0.0432 0.082 0.082
Trypanosoma cruzi hypothetical protein, conserved 0.0362 0.0636 0.0628
Plasmodium vivax calcium-dependent protein kinase, putative 0.0227 0.0281 0.0231
Schistosoma mansoni titin 0.0276 0.0411 0.0402
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1364 0.3261 0.2803
Leishmania major protein kinase, putative 0.0345 0.0592 0.0523
Plasmodium falciparum protein kinase, putative 0.0147 0.0073 0.0022
Loa Loa (eye worm) hypothetical protein 0.0176 0.0148 0.0148
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0399 0.0734 0.0734
Toxoplasma gondii NADPH-glutathione reductase 0.1364 0.3261 0.3212
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Echinococcus multilocularis sodium and chloride dependent glycine 0.0159 0.0105 0.0056
Schistosoma mansoni protein kinase 0.0497 0.0989 0.0981
Schistosoma mansoni titin 0.0182 0.0163 0.0154
Giardia lamblia Kinase, CMGC CDK 0.0267 0.0387 0.0682
Echinococcus granulosus tyrosine protein kinase Lyn 0.0418 0.0783 0.0737
Echinococcus multilocularis dual specificity 0.0275 0.0407 0.036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0311 0.0303
Loa Loa (eye worm) hypothetical protein 0.0254 0.0352 0.0352
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0344 0.0589 0.0542
Onchocerca volvulus 0.0432 0.082 0.3701
Entamoeba histolytica cysteine proteinase, putative 0.0254 0.0352 0.1726
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.0194 0.0145
Loa Loa (eye worm) hypothetical protein 0.1132 0.2653 0.2653
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0456 0.0881 0.0836
Loa Loa (eye worm) AGC/NDR protein kinase 0.0362 0.0636 0.0636
Echinococcus granulosus cyclin dependent kinase 0.0267 0.0387 0.0339
Loa Loa (eye worm) CDC7 protein kinase 0.0202 0.0216 0.0216
Echinococcus multilocularis glutamate synthase 0.0362 0.0636 0.0589
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Schistosoma mansoni ste20-related kinase 0.0461 0.0896 0.0888
Loa Loa (eye worm) Notch2 0.0398 0.0729 0.0729
Toxoplasma gondii histone kinase SNF1, putative 0.0176 0.0148 0.0076
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0232 0.0294 0.0294
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2118 0.5238 0.5238
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.0177 0.0126
Trypanosoma cruzi cysteine peptidase, putative 0.0254 0.0352 0.0344
Brugia malayi basement membrane proteoglycan 0.0218 0.0258 0.0249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0188 0.018 0.0172
Echinococcus multilocularis protein kinase c epsilon type 0.0459 0.089 0.0844
Brugia malayi Prion-like- 0.0399 0.0734 0.0725
Brugia malayi Heparan sulfate 0.0218 0.0258 0.0249
Plasmodium vivax casein kinase 1, putative 0.0244 0.0327 0.0277
Plasmodium falciparum glycogen synthase kinase 3 0.0289 0.0445 0.0396
Echinococcus multilocularis cathepsin L cysteine protease 0.0254 0.0352 0.0304
Schistosoma mansoni protein kinase 0.0264 0.038 0.0372
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.0592 0.0584
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.018 0.0553
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0159 0.0105 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Plasmodium vivax unspecified product 0.0225 0.0277 0.0227
Onchocerca volvulus 0.0254 0.0352 0.1557
Echinococcus granulosus neurogenic locus notch protein 0.0398 0.0729 0.0683
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Schistosoma mansoni ephrin receptor 0.0217 0.0256 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.1073 0.2498 0.2491
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0344 0.0589 0.0542
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0493 0.0978 0.0933
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.05 0.0996 0.0952
Echinococcus multilocularis neurogenic locus notch protein 4 0.0398 0.0729 0.0683
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0227 0.0281 0.0233
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0362 0.0636 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0267 0.0387 0.0316
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0358 0.0625 0.0616
Echinococcus multilocularis mitogen activated protein kinase 0.0188 0.018 0.0131
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0793 0.1765 0.1724
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0138 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Loa Loa (eye worm) TK/ABL protein kinase 0.0148 0.0074 0.0074
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0218 0.0258 0.0258
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0138 0.005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0182 0.0164 0.0092
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1112 0.26 0.2564
Echinococcus multilocularis hypothetical protein 0.0229 0.0288 0.0239
Brugia malayi Prion-like- 0.0182 0.0163 0.0154
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0182 0.0165 0.0116
Plasmodium vivax serine/threonine kinase-1, putative 0.0345 0.0592 0.0544
Echinococcus multilocularis aurora kinase A 0.0264 0.038 0.0332
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Trichomonas vaginalis STE family protein kinase 0.0193 0.0194 0.0594
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.0194 0.0145
Toxoplasma gondii AGC kinase 0.0254 0.0353 0.0282
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Brugia malayi serine/threonine-protein kinase PAK 7 0.0522 0.1055 0.1047
Echinococcus multilocularis titin 0.0182 0.0163 0.0114
Loa Loa (eye worm) hypothetical protein 0.0448 0.086 0.086
Brugia malayi C1-like domain containing protein 0.0489 0.0969 0.0961
Onchocerca volvulus 0.0244 0.0327 0.1442
Echinococcus multilocularis casein kinase i 0.0244 0.0327 0.0279
Echinococcus multilocularis serine:threonine protein kinase N2 0.0292 0.0451 0.0404
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0182 0.0164 0.0113
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0254 0.0352 0.0352
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0244 0.0327 0.0327
Echinococcus granulosus tyrosine protein kinase HCK 0.0206 0.0227 0.0178
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0325 0.054 0.0493
Echinococcus granulosus Protein kinase C brain isozyme 0.0548 0.1123 0.1079
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0176 0.0148 0.0097
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1364 0.3261 1
Entamoeba histolytica protein kinase, putative 0.0312 0.0506 0.2607
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.0051 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Schistosoma mansoni septate junction protein 0.0399 0.0734 0.0725
Entamoeba histolytica protein kinase, putative 0.0275 0.0407 0.2041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Onchocerca volvulus 0.0182 0.0163 0.069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Loa Loa (eye worm) hypothetical protein 0.0268 0.0388 0.0388
Schistosoma mansoni neuroglian 0.042 0.0787 0.0779
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.087 0.0862
Schistosoma mansoni cell adhesion molecule 0.042 0.0787 0.0779
Onchocerca volvulus 0.0415 0.0776 0.3496
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0182 0.0163 0.0114
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1052 0.2445 0.2438
Echinococcus granulosus serotonin transporter 0.0159 0.0105 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0489 0.15
Onchocerca volvulus 0.0734 0.1611 0.7325
Schistosoma mansoni basigin related 0.0218 0.0258 0.0249
Brugia malayi Protein kinase domain 0.0193 0.0194 0.0185
Schistosoma mansoni g1/s-specific cyclin C 0.1583 0.3836 0.3831
Brugia malayi Protein kinase domain containing protein 0.0719 0.1571 0.1563
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.1002 0.2312 0.2306
Giardia lamblia Kinase, CMGC CLK 0.0345 0.0592 0.1348
Entamoeba histolytica protein kinase, putative 0.0362 0.0636 0.3352
Entamoeba histolytica cell division protein kinase 2, putative 0.0267 0.0387 0.1925
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.0592 0.0584
Brugia malayi Protein kinase domain containing protein 0.0316 0.0516 0.0508
Loa Loa (eye worm) hypothetical protein 0.0138 0.005 0.005
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0167 0.0167
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3212
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0168 0.0129 0.0129
Loa Loa (eye worm) TK/INSR protein kinase 0.0676 0.1459 0.1459
Giardia lamblia Aurora kinase 0.0264 0.038 0.0661
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0184 0.0175
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1709 0.4167 0.4167
Leishmania major cysteine peptidase A (CPA) 0.0254 0.0352 0.0281
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0716 0.1564 0.1556
Plasmodium falciparum cGMP-dependent protein kinase 0.019 0.0184 0.0133
Onchocerca volvulus Serine\/threonine kinase homolog 0.0369 0.0654 0.2938
Echinococcus multilocularis sodium and chloride dependent glycine 0.0159 0.0105 0.0056
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1364 0.3261 0.3226
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.0435 0.0427
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0793 0.1765 0.1724
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0339 0.0576 0.0576
Trichomonas vaginalis glutamate synthase, putative 0.0362 0.0636 0.195
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1364 0.3261 0.3226
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Onchocerca volvulus 0.0202 0.0217 0.0936
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0167 0.0126 0.0117
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0362 0.0636 0.195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Echinococcus granulosus dual specificity 0.0312 0.0506 0.0459
Entamoeba histolytica protein kinase, putative 0.0657 0.1409 0.779
Entamoeba histolytica serine/threonine protein kinase, putative 0.0176 0.0148 0.0554
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0399 0.0734 0.0687
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Giardia lamblia Kinase, CK1 Casein kinase 0.0244 0.0327 0.0488
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0159 0.0105 0.0096
Echinococcus multilocularis tyrosine protein kinase 0.0346 0.0594 0.0547
Echinococcus granulosus titin 0.0182 0.0163 0.0114
Schistosoma mansoni hypothetical protein 0.0184 0.0169 0.016
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0608 0.128 0.1236
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0218 0.0258 0.0249
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0362 0.0636 0.0567
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0362 0.0636 0.195
Giardia lamblia Kinase, AGC PKA 0.0254 0.0353 0.0572
Brugia malayi Sex muscle abnormal protein 5 0.0138 0.005 0.0041
Treponema pallidum NADH oxidase 0.1364 0.3261 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Loa Loa (eye worm) hypothetical protein 0.0159 0.0105 0.0105
Echinococcus multilocularis cGMP dependent protein kinase 1 0.019 0.0184 0.0135
Onchocerca volvulus 0.0182 0.0165 0.0697
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0227 0.0281 0.0233
Entamoeba histolytica PH domain containing protein kinase, putative 0.0369 0.0655 0.346
Giardia lamblia Kinase, CMGC CDK 0.0267 0.0387 0.0682
Trypanosoma cruzi casein kinase, delta isoform, putative 0.017 0.0133 0.0125
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0312 0.0506 0.0506
Brugia malayi protein unc-22 0.0276 0.0411 0.0402
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0345 0.0592 0.0592
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0285 0.0435 0.0427
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0186 0.0177
Trichomonas vaginalis AGC family protein kinase 0.0385 0.0697 0.2136
Echinococcus multilocularis 0.0344 0.0589 0.0543
Echinococcus multilocularis death associated protein kinase 1 0.1001 0.2311 0.2273
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0594 0.1244 0.1201
Trypanosoma cruzi cdc2-related kinase 3 0.0267 0.0387 0.0378
Loa Loa (eye worm) hypothetical protein 0.0273 0.0402 0.0402
Echinococcus granulosus CDC7 cell division cycle 7 0.0202 0.0216 0.0167
Echinococcus multilocularis geminin 0.0184 0.0169 0.012
Loa Loa (eye worm) programmed cell death 8 0.0362 0.0636 0.0636
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0749 0.165 0.165
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0432 0.1324
Echinococcus multilocularis serine:threonine protein kinase 0.0256 0.0359 0.0311
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Onchocerca volvulus 0.0148 0.0074 0.0281
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0934 0.2134 0.2095
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Trichomonas vaginalis AGC family protein kinase 0.0385 0.0697 0.2136
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0227 0.0281 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0167 0.0158
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0608 0.128 0.128
Trichomonas vaginalis apoptosis inducing factor, putative 0.0362 0.0636 0.195
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0352 0.061 0.0563
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1364 0.3261 0.3255
Entamoeba histolytica cysteine protease, putative 0.0254 0.0352 0.1726
Schistosoma mansoni tyrosine kinase 0.0471 0.0922 0.0914
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0362 0.0636 0.0567
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Onchocerca volvulus 0.0182 0.0163 0.069
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0264 0.038 0.1887
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Schistosoma mansoni cell adhesion molecule 0.0399 0.0734 0.0725
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0482 0.0473
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1364 0.3261 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0255 0.0355 0.0355
Entamoeba histolytica protein kinase, putative 0.0162 0.0111 0.034
Schistosoma mansoni glutamate synthase 0.0362 0.0636 0.0628
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0344 0.0589 0.0542
Echinococcus granulosus growth factor receptor bound protein 2 0.014 0.0055 0.0006
Onchocerca volvulus 0.0254 0.0352 0.1557
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0251 0.0346 0.0337
Echinococcus multilocularis mitogen activated protein kinase 11 0.0358 0.0625 0.0578
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.018 0.0553
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0227 0.0281 0.021
Onchocerca volvulus 0.0159 0.0105 0.0423
Trypanosoma cruzi cdc2-related kinase 1 0.0267 0.0387 0.0378
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0231 0.0223
Brugia malayi Serine/threonine-protein kinase SULU 0.05 0.0996 0.0988
Schistosoma mansoni growth factor receptor-bound protein 0.014 0.0055 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0256 0.0359 0.1102
Brugia malayi hypothetical protein 0.0159 0.0105 0.0096
Trichomonas vaginalis STE family protein kinase 0.0306 0.0489 0.15
Schistosoma mansoni cell adhesion molecule 0.0218 0.0258 0.0249
Entamoeba histolytica protein kinase, putative 0.0162 0.0111 0.034
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0238 0.0311 0.0263
Echinococcus multilocularis neuroglian 0.0898 0.204 0.2
Schistosoma mansoni tyrosine kinase 0.0316 0.0515 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0281 0.0273
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0254 0.0353 0.0344
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0793 0.1765 0.8027
Echinococcus granulosus mitogen activated protein kinase 3 0.0188 0.018 0.0131
Brugia malayi Immunoglobulin domain containing protein 0.0218 0.0258 0.0249
Onchocerca volvulus 0.0148 0.0074 0.0281
Brugia malayi cell division control protein 2 homolog 0.0267 0.0387 0.0378
Trichomonas vaginalis STE family protein kinase 0.0193 0.0194 0.0594
Onchocerca volvulus 0.0251 0.0346 0.1528
Loa Loa (eye worm) hypothetical protein 0.0522 0.1054 0.1054
Schistosoma mansoni cathepsin F (C01 family) 0.0254 0.0352 0.0344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Plasmodium vivax serine/threonine protein kinase, putative 0.0187 0.0177 0.0126
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0608 0.128 0.1236
Echinococcus granulosus slit 2 protein 0.0448 0.086 0.0815
Echinococcus multilocularis raf serine:threonine protein kinase 0.0167 0.0126 0.0077
Trypanosoma cruzi cdc2-related kinase 1 0.0267 0.0387 0.0378
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0886 0.201 0.201
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0369 0.0655 0.0646
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0289 0.0445 0.0398
Schistosoma mansoni tyrosine kinase 0.0453 0.0875 0.0867
Brugia malayi protein kinase C3,putative 0.0354 0.0616 0.0608
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.02 0.0211 0.0211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Loa Loa (eye worm) ctsf protein 0.0254 0.0352 0.0352
Echinococcus granulosus hypothetical protein 0.0271 0.0399 0.0351
Brugia malayi Immunoglobulin I-set domain containing protein 0.0283 0.0428 0.042
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0385 0.0697 0.0697
Leishmania major hypothetical protein, conserved 0.0362 0.0636 0.0567
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1075 0.2505 0.2505
Echinococcus multilocularis contactin neuroglian septate junction protein 0.042 0.0787 0.0741
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0188 0.018 0.0172
Echinococcus granulosus lachesin 0.0399 0.0734 0.0687
Loa Loa (eye worm) hypothetical protein 0.0419 0.0786 0.0786
Brugia malayi Protein kinase domain containing protein 0.0275 0.0407 0.0399
Entamoeba histolytica casein kinase, putative 0.0225 0.0277 0.1293
Loa Loa (eye worm) TK protein kinase 0.0418 0.0783 0.0783
Schistosoma mansoni septate junction protein 0.0218 0.0258 0.0249
Onchocerca volvulus Cathepsin L homolog 0.0254 0.0352 0.1557
Echinococcus granulosus dual specificity 0.0275 0.0407 0.036
Echinococcus granulosus serine:threonine protein kinase 0.0256 0.0359 0.0311
Loa Loa (eye worm) TK/FER protein kinase 0.0148 0.0074 0.0074
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0358 0.0625 0.0576
Brugia malayi Temporarily assigned gene name protein 59 0.029 0.0448 0.0439
Toxoplasma gondii CMGC kinase, CK2 family 0.0225 0.0277 0.0205
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Onchocerca volvulus Cathepsin F homolog 0.0254 0.0352 0.1557
Echinococcus multilocularis transfer RNA-Phe 0.0202 0.0217 0.0168
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0362 0.0636 0.0588
Brugia malayi hypothetical protein 0.0737 0.1618 0.161
Onchocerca volvulus 0.0148 0.0074 0.0281
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.1002 0.2312 0.2306
Echinococcus multilocularis mitogen activated protein kinase 14 0.0358 0.0625 0.0578
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1364 0.3261 0.3226
Loa Loa (eye worm) AGC/PKG protein kinase 0.019 0.0184 0.0184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0734 0.0725
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Trypanosoma cruzi cysteine peptidase, putative 0.0254 0.0352 0.0344
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0486 0.096 0.0915
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0216 0.0662
Trypanosoma cruzi cysteine protease, putative 0.0139 0.0051 0.0043
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0345 0.0592 0.0544
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0456 0.0881 0.0836
Brugia malayi MAP kinase sur-1 0.0188 0.018 0.0172
Onchocerca volvulus Tyrosine kinase homolog 0.0957 0.2195 1
Echinococcus granulosus tyrosine protein kinase shark 0.039 0.071 0.0664
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0124 0.0012 0.0012
Plasmodium vivax glutathione reductase, putative 0.3936 1 1
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Entamoeba histolytica protein kinase, putative 0.0148 0.0076 0.014
Brugia malayi pregnancy-associated plasma protein-A 0.0734 0.1611 0.1604
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0345 0.0592 0.0523
Brugia malayi p70 ribosomal S6 kinase beta 0.064 0.1365 0.1357
Echinococcus granulosus serine/threonine protein kinase 0.0369 0.0655 0.0608
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0306 0.0489 0.044
Giardia lamblia Kinase, CAMK CAMKL 0.0193 0.0192 0.005
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0168 0.0129 0.012
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0716 0.1564 0.1556
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3255
Schistosoma mansoni serine/threonine protein kinase 0.0594 0.1244 0.1237
Echinococcus granulosus tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Trypanosoma brucei rac serine-threonine kinase, putative 0.0657 0.1409 0.1365
Echinococcus multilocularis insulin growth factor binding 0.0182 0.0163 0.0114
Brugia malayi Fibronectin type III domain containing protein 0.0737 0.1618 0.161
Trypanosoma cruzi trypanothione reductase, putative 0.1364 0.3261 0.3255
Loa Loa (eye worm) hypothetical protein 0.0737 0.1618 0.1618
Plasmodium falciparum cysteine proteinase falcipain 3 0.0254 0.0352 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.0636 0.0627
Loa Loa (eye worm) hypothetical protein 0.0167 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0144 0.0065 0.0065
Echinococcus granulosus Vam6:Vps39 protein 0.0251 0.0346 0.0298
Giardia lamblia Kinase, CMGC MAPK 0.0188 0.018 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Loa Loa (eye worm) hypothetical protein 0.0312 0.0505 0.0505
Toxoplasma gondii aurora kinase 0.0264 0.038 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Echinococcus granulosus neurogenic locus protein delta 0.0398 0.0729 0.0683
Echinococcus granulosus titin 0.0276 0.0411 0.0363
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1364 0.3261 0.2803
Brugia malayi Protein kinase domain containing protein 0.0825 0.1848 0.1841
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0183 0.0167 0.0118
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0218 0.0258 0.0209
Trichomonas vaginalis mercuric reductase, putative 0.1364 0.3261 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0528 0.1072 0.1027
Echinococcus granulosus neurogenic locus notch protein 4 0.0398 0.0729 0.0683
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0251 0.0346 0.0298
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Brugia malayi Prion-like- 0.0182 0.0163 0.0154
Schistosoma mansoni atypical protein kinase C 0.0656 0.1407 0.1399
Echinococcus granulosus glutamate synthase 0.0362 0.0636 0.0589
Echinococcus granulosus fibropellin Ia 0.0398 0.0729 0.0683
Echinococcus multilocularis neuroglian 0.042 0.0787 0.0741
Echinococcus granulosus N chimaerin 0.0168 0.0129 0.0079
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Echinococcus granulosus protein kinase c epsilon type 0.0459 0.089 0.0844
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Schistosoma mansoni hypothetical protein 0.0218 0.0258 0.0249
Echinococcus granulosus casein kinase i 0.0244 0.0327 0.0279
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0362 0.0636 0.0628
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0263 0.0377 0.0368
Schistosoma mansoni nephrin 0.042 0.0787 0.0779
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Echinococcus multilocularis hemicentin 1 0.0399 0.0734 0.0687
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0362 0.0636 0.0589
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0761 0.1682 0.1682
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0544 0.1114 0.107
Echinococcus multilocularis tyrosine protein kinase Fyn 0.028 0.0421 0.0374
Onchocerca volvulus Putative titin 0.0182 0.0163 0.069
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0594 0.1244 0.1244
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0285 0.0435 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0254 0.0352 0.108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0737 0.1618 0.161
Brugia malayi Papain family cysteine protease containing protein 0.0139 0.0051 0.0043
Plasmodium falciparum calcium-dependent protein kinase 4 0.0227 0.0281 0.0231
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0218 0.0258 0.0209
Echinococcus granulosus fibroblast growth factor receptor 4 0.0409 0.0759 0.0713
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0327 0.0279
Onchocerca volvulus 0.0182 0.0163 0.069
Echinococcus multilocularis cyclin dependent kinase 9 0.0187 0.0177 0.0128
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0267 0.0387 0.0387
Echinococcus multilocularis mitogen activated protein kinase 11 0.0358 0.0625 0.0578
Loa Loa (eye worm) hypothetical protein 0.0193 0.0193 0.0193
Loa Loa (eye worm) AUR protein kinase 0.0264 0.038 0.038
Giardia lamblia Kinase, NEK 0.0306 0.0489 0.1014
Plasmodium vivax glycogen synthase kinase 3, putative 0.0289 0.0445 0.0396
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0168 0.0129 0.012
Schistosoma mansoni tyrosine kinase 0.0344 0.0589 0.0581
Echinococcus multilocularis casein kinase I delta 0.0244 0.0327 0.0279
Loa Loa (eye worm) CAMK protein kinase 0.0276 0.0411 0.0411
Entamoeba histolytica protein kinase, putative 0.0193 0.0194 0.0817
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0548 0.1123 0.1079
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Echinococcus granulosus titin 0.0182 0.0163 0.0114
Trypanosoma cruzi trypanothione reductase, putative 0.3936 1 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0168 0.0168
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0227 0.0281 0.0273
Schistosoma mansoni septate junction protein 0.0399 0.0734 0.0725
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0515 0.1036 0.0992
Loa Loa (eye worm) protein kinase domain-containing protein 0.0479 0.0944 0.0944
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0976 0.2244 0.2206
Echinococcus granulosus c-Jun N-terminal kinases 0.0594 0.1244 0.1201
Plasmodium falciparum calcium-dependent protein kinase 5 0.0227 0.0281 0.0231
Echinococcus multilocularis ephrin type A receptor 4 A 0.0217 0.0256 0.0208
Echinococcus granulosus protein jagged 1 0.0398 0.0729 0.0683
Loa Loa (eye worm) glutathione reductase 0.3936 1 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0254 0.0353 0.0344
Schistosoma mansoni cell adhesion molecule 0.0954 0.2188 0.2181
Echinococcus granulosus dual specificity protein kinase clk2 0.0345 0.0592 0.0545
Brugia malayi casein kinase 1, delta 0.0244 0.0327 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0281 0.0862
Schistosoma mansoni sodium-dependent amino acid transporter 0.0159 0.0105 0.0096
Brugia malayi cyclin-dependent kinase 9 0.017 0.0133 0.0124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0258 0.0249
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0289 0.0445 0.0398
Echinococcus multilocularis protein jagged 2 0.0398 0.0729 0.0683
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0254 0.0353 0.0303
Schistosoma mansoni hypothetical protein 0.0251 0.0346 0.0337
Onchocerca volvulus 0.0142 0.006 0.022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0216 0.0662
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0387 0.1187
Brugia malayi Immunoglobulin domain containing protein 0.0218 0.0258 0.0249
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0353 0.0344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Onchocerca volvulus 0.0202 0.0216 0.0932
Echinococcus multilocularis Glutaredoxin protein 5 0.0278 0.0416 0.0369
Brugia malayi Tyrosine-protein kinase abl-1 0.0211 0.0241 0.0233
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.018 0.0159 0.011
Onchocerca volvulus 0.0254 0.0352 0.1557
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0697 0.1513 0.1471
Toxoplasma gondii thioredoxin reductase 0.3936 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0139 0.0051 0.0043
Echinococcus multilocularis thioredoxin glutathione reductase 0.3936 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0267 0.0387 0.0339
Onchocerca volvulus 0.0148 0.0074 0.0281
Schistosoma mansoni glutamate synthase 0.0362 0.0636 0.0628
Echinococcus granulosus aurora kinase A 0.0264 0.038 0.0332
Echinococcus multilocularis serotonin transporter 0.0159 0.0105 0.0056
Giardia lamblia High cysteine protein 0.0398 0.0729 0.1792
Brugia malayi Variant SH3 domain containing protein 0.0138 0.005 0.0041
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1364 0.3261 0.3212
Schistosoma mansoni serine/threonine protein kinase 0.05 0.0996 0.0988
Echinococcus granulosus cysteine protease 0.0139 0.0051 0.0002
Schistosoma mansoni nephrin related 0.0182 0.0163 0.0154
Entamoeba histolytica protein kinase domain containing protein 0.017 0.0133 0.0467
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Leishmania major trypanothione reductase 0.3936 1 1
Brugia malayi Protein kinase domain containing protein 0.0362 0.0636 0.0627
Schistosoma mansoni serine/threonine protein kinase 0.1075 0.2505 0.2498
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0238 0.0311 0.0311
Onchocerca volvulus 0.0254 0.0352 0.1557
Echinococcus granulosus protein jagged 2 0.0398 0.0729 0.0683
Loa Loa (eye worm) hypothetical protein 0.0674 0.1454 0.1454
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.042 0.0787 0.0779
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0657 0.1409 0.4322
Echinococcus multilocularis rho associated protein kinase 0.0731 0.1603 0.1561
Loa Loa (eye worm) LAD-2 short isoform 0.0218 0.0258 0.0258
Loa Loa (eye worm) casein kinase 0.0405 0.075 0.075
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.017 0.0133 0.0133
Onchocerca volvulus 0.0734 0.1611 0.7325
Echinococcus granulosus casein kinase I delta 0.0244 0.0327 0.0279
Schistosoma mansoni protein kinase 0.0596 0.1248 0.124
Plasmodium falciparum casein kinase 1 0.0244 0.0327 0.0277
Echinococcus multilocularis cyclin dependent kinase 0.0267 0.0387 0.0339
Schistosoma mansoni serine/threonine kinase 0.0362 0.0636 0.0627
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0227 0.0281 0.021
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0267 0.0387 0.0316
Echinococcus granulosus protein jagged 2 0.0398 0.0729 0.0683
Echinococcus multilocularis casein kinase I delta 0.0244 0.0327 0.0279
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0275 0.0407 0.0399
Echinococcus multilocularis serine:threonine protein kinase 0.0256 0.0359 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.0636 0.0627
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0159 0.0105 0.0096
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.042 0.0787 0.0741
Onchocerca volvulus Slit protein homolog 0.0448 0.086 0.3884
Schistosoma mansoni titin 0.0182 0.0163 0.0154
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0163 0.0163
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0275 0.0407 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0254 0.0352 0.108
Brugia malayi EGF-like domain containing protein 0.0398 0.0729 0.0721
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.019 0.0186 0.0771
Brugia malayi EGF-like domain containing protein 0.0448 0.086 0.0852
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0254 0.0352 0.108
Brugia malayi probable protein kinase 0.0596 0.1248 0.124
Plasmodium falciparum ferrodoxin reductase-like protein 0.0362 0.0636 0.0588
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Brugia malayi Variant SH3 domain containing protein 0.0168 0.0129 0.012
Brugia malayi Protein kinase domain containing protein 0.0346 0.0594 0.0585
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Echinococcus multilocularis dual specificity 0.0312 0.0506 0.0459
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0148 0.0074 0.0025
Echinococcus granulosus tyrosine protein kinase Src42A 0.0344 0.0589 0.0542
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0264 0.038 0.0331
Echinococcus granulosus insulin growth factor binding 0.0182 0.0163 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0254 0.0352 0.0344
Onchocerca volvulus 0.0734 0.1611 0.7325
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1364 0.3261 0.2803
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0482 0.0473
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Schistosoma mansoni hypothetical protein 0.0182 0.0163 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0216 0.0207
Leishmania major protein kinase A catalytic subunit isoform 2 0.0254 0.0353 0.0282
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0159 0.0105 0.0056
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0123 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0362 0.0636 0.0628
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0344 0.0589 0.0542
Echinococcus multilocularis CDC7 cell division cycle 7 0.0202 0.0216 0.0167
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0096
Giardia lamblia Kinase, CAMK CAMKL 0.0193 0.0192 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.1709 0.4167 0.4161
Plasmodium falciparum glutathione reductase 0.1364 0.3261 0.3226
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1364 0.3261 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Onchocerca volvulus 0.0734 0.1611 0.7325
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0227 0.0281 0.0281
Echinococcus granulosus cathepsin l1 0.0167 0.0126 0.0077
Schistosoma mansoni tyrosine kinase 0.0649 0.1387 0.138
Echinococcus multilocularis protein jagged 1 0.0398 0.0729 0.0683
Echinococcus granulosus protein jagged 1 0.0398 0.0729 0.0683
Echinococcus multilocularis cGMP dependent protein kinase 1 0.019 0.0184 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0506 0.1551
Brugia malayi Cathepsin L-like precursor 0.0167 0.0126 0.0117
Leishmania major casein kinase II, putative 0.0225 0.0277 0.0205
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0159 0.0105 0.0032
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.05 0.0996 0.0996
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0352 0.061 0.0563
Brugia malayi Cathepsin L-like precursor 0.0254 0.0352 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Onchocerca volvulus 0.0362 0.0636 0.2856
Loa Loa (eye worm) hypothetical protein 0.0399 0.0734 0.0734
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0225 0.0277 0.0277
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0353 0.1082
Loa Loa (eye worm) hypothetical protein 0.042 0.0787 0.0787
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0278 0.0416 0.0369
Schistosoma mansoni protein kinase 0.0193 0.0194 0.0185
Schistosoma mansoni tyrosine kinase 0.0544 0.1114 0.1106
Echinococcus multilocularis rac serine:threonine kinase 0.0369 0.0655 0.0608
Loa Loa (eye worm) projectin 0.0202 0.0217 0.0217
Brugia malayi hypothetical protein 0.0734 0.1611 0.1604
Echinococcus granulosus raf serine:threonine protein kinase 0.0167 0.0126 0.0077
Schistosoma mansoni notch 0.0398 0.0729 0.0721
Onchocerca volvulus Neurogenic locus notch homolog 0.0398 0.0729 0.3284
Schistosoma mansoni serine/threonine protein kinase 0.0551 0.1131 0.1124
Echinococcus granulosus NDR protein kinase 0.0362 0.0636 0.0589
Loa Loa (eye worm) AUR protein kinase 0.0264 0.038 0.038
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0362 0.0636 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Echinococcus granulosus sodium and chloride dependent glycine 0.0159 0.0105 0.0056
Entamoeba histolytica p21-activated kinase 0.021 0.0238 0.1073
Echinococcus multilocularis PAK box P21 Rho binding 0.0144 0.0066 0.0016
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.1052 0.2445 0.2407
Echinococcus granulosus tyrosine protein kinase Fyn 0.0344 0.0589 0.0542
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0182 0.0163 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Brugia malayi cathepsin B-like cysteine proteinase 0.0191 0.0187 0.0178
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0409 0.0759 0.0713
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0344 0.0589 0.0542
Brugia malayi Protein kinase domain containing protein 0.0148 0.0074 0.0065
Brugia malayi Protein kinase domain containing protein 0.0148 0.0074 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Trichomonas vaginalis CAMK family protein kinase 0.0488 0.0966 0.2961
Echinococcus multilocularis cathepsin b 0.0191 0.0187 0.0138
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0398 0.0729 0.0729
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0456 0.0881 0.0881
Onchocerca volvulus 0.0148 0.0074 0.0281
Loa Loa (eye worm) hypothetical protein 0.0218 0.0258 0.0258
Schistosoma mansoni cell adhesion molecule 0.042 0.0787 0.0779
Echinococcus multilocularis cysteine protease 0.0254 0.0352 0.0304
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0193 0.0194 0.0145
Echinococcus multilocularis tyrosine protein kinase shark 0.039 0.071 0.0664
Brugia malayi Protein kinase domain containing protein 0.0656 0.1405 0.1398
Schistosoma mansoni titin 0.0182 0.0163 0.0154
Schistosoma mansoni glutamate synthase 0.0362 0.0636 0.0628
Brugia malayi Immunoglobulin domain containing protein 0.0218 0.0258 0.0249
Echinococcus multilocularis lachesin 0.0399 0.0734 0.0687
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3936 1 1
Schistosoma mansoni cell polarity protein 0.0398 0.0729 0.0721
Echinococcus multilocularis cysteine protease 0.0254 0.0352 0.0304
Loa Loa (eye worm) hypothetical protein 0.0734 0.1611 0.1611
Schistosoma mansoni cell adhesion molecule 0.0202 0.0217 0.0208
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0976 0.2244 0.2206
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0506 0.0497
Entamoeba histolytica hypothetical protein 0.0432 0.082 0.4409
Echinococcus granulosus tyrosine protein kinase Src42A 0.0209 0.0236 0.0187
Loa Loa (eye worm) hypothetical protein 0.04 0.0735 0.0735
Entamoeba histolytica serine/threonine protein kinase, putative 0.0608 0.128 0.7046
Brugia malayi kettin 0.0182 0.0163 0.0154
Brugia malayi hypothetical protein 0.0148 0.0074 0.0065
Trypanosoma cruzi polo-like protein kinase, putative 0.0608 0.128 0.1272
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0445 0.1365
Brugia malayi Calcium binding EGF domain containing protein 0.0398 0.0729 0.0721
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.019 0.0186 0.0771
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0445 0.2259
Leishmania major cathepsin L-like protease 0.0254 0.0352 0.0281
Entamoeba histolytica protein kinase, putative 0.0187 0.0177 0.0718
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0577 0.12 0.12
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0254 0.0353 0.0282
Onchocerca volvulus 0.0734 0.1611 0.7325
Loa Loa (eye worm) TK protein kinase 0.0206 0.0227 0.0227
Onchocerca volvulus 0.0398 0.0729 0.3284
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0182 0.0163 0.0154
Trypanosoma cruzi casein kinase, putative 0.0244 0.0327 0.0319
Echinococcus granulosus dual specificity 0.0312 0.0506 0.0459
Plasmodium falciparum transporter, putative 0.0159 0.0105 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0432 0.1324
Echinococcus granulosus neuroglian 0.0898 0.204 0.2
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0188 0.018 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0148 0.0139
Trypanosoma cruzi cysteine peptidase, putative 0.0254 0.0352 0.0344
Plasmodium falciparum glutathione reductase 0.3936 1 1
Echinococcus multilocularis neural cadherin 0.0398 0.0729 0.0683
Trichomonas vaginalis glutamate synthase, putative 0.0362 0.0636 0.195
Echinococcus multilocularis epidermal growth factor receptor 0.0544 0.1114 0.107
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.038 0.0372
Brugia malayi ephrin receptor 1 precursor 0.0141 0.0057 0.0048
Echinococcus multilocularis serine:threonine protein kinase 3 0.0577 0.12 0.1157
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.096 0.0952
Giardia lamblia Kinase, STE STE20 0.0193 0.0194 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0592 0.0584
Brugia malayi Stress-activated protein kinase jnk-1 0.0594 0.1244 0.1237
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0486 0.096 0.0915
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0278 0.0416 0.0369
Echinococcus granulosus Immunoglobulin 0.0716 0.1564 0.1522
Toxoplasma gondii rhoptry neck protein RON1 0.0734 0.1611 0.155
Echinococcus multilocularis cyclin 0.0793 0.1765 0.1724
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Echinococcus granulosus cyclin 0.0793 0.1765 0.1724
Echinococcus granulosus expressed protein 0.0187 0.0177 0.0128
Entamoeba histolytica PH domain containing protein kinase, putative 0.0271 0.0398 0.1986
Trichomonas vaginalis STE family protein kinase 0.019 0.0186 0.057
Echinococcus granulosus calcium dependent protein kinase 0.0153 0.0087 0.0038
Schistosoma mansoni basigin related 0.0218 0.0258 0.0249
Plasmodium vivax vivapain-2 0.0254 0.0352 0.0303
Schistosoma mansoni myosin-binding protein-related 0.0202 0.0217 0.0208
Entamoeba histolytica casein kinase 1, putative 0.0244 0.0327 0.1582
Echinococcus multilocularis titin 0.0182 0.0163 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0353 0.0344
Giardia lamblia Kinase, CMGC CK2 0.0225 0.0277 0.0325
Echinococcus multilocularis cathepsin L 0.0139 0.0051 0.0002
Onchocerca volvulus 0.0289 0.0445 0.1982
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0227 0.0281 0.0231
Toxoplasma gondii hypothetical protein 0.0159 0.0105 0.0032
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0244 0.0327 0.0327
Echinococcus granulosus cathepsin L cysteine proteinase 0.0254 0.0352 0.0304
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0353 0.0305
Echinococcus granulosus sodium and chloride dependent glycine 0.0159 0.0105 0.0056
Echinococcus multilocularis mitogen activated protein kinase 3 0.0188 0.018 0.0131
Echinococcus granulosus mitogen activated protein kinase 11 0.0358 0.0625 0.0578
Plasmodium falciparum calcium-dependent protein kinase 2 0.0227 0.0281 0.0231
Loa Loa (eye worm) norepinephrine transporter 0.0159 0.0105 0.0105
Echinococcus granulosus tyrosine protein kinase Src64B 0.0344 0.0589 0.0542
Toxoplasma gondii selenide, water dikinase 0.0362 0.0636 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0277 0.0849
Echinococcus multilocularis cyclin dependent kinase 1 0.0267 0.0387 0.0339
Trichomonas vaginalis AGC family protein kinase 0.02 0.0211 0.0647
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0793 0.1765 0.1765
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0398 0.0729 0.3284
Plasmodium falciparum serine/threonine protein kinase 0.0187 0.0177 0.0126
Trypanosoma brucei Casein kinase II 0.0225 0.0277 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Brugia malayi Hr1 repeat family protein 0.0654 0.14 0.1392
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0365 0.112
Loa Loa (eye worm) hypothetical protein 0.0218 0.0258 0.0258
Echinococcus granulosus casein kinase I delta 0.0244 0.0327 0.0279
Brugia malayi Protein kinase domain containing protein 0.0256 0.0359 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Loa Loa (eye worm) AUR protein kinase 0.0264 0.038 0.038
Brugia malayi Cadherin domain containing protein 0.0398 0.0729 0.0721
Brugia malayi Papain family cysteine protease containing protein 0.0254 0.0352 0.0344
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0188 0.018 0.0172
Loa Loa (eye worm) TK/FER protein kinase 0.0493 0.0978 0.0978
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0312 0.0506 0.0436
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0362 0.0636 0.0628
Schistosoma mansoni basigin related 0.0218 0.0258 0.0249
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0608 0.128 0.1216
Plasmodium vivax ferrodoxin reductase, putative 0.0362 0.0636 0.0588
Echinococcus granulosus nervana 2 0.0278 0.0416 0.0369
Echinococcus multilocularis neurogenic locus notch protein 0.0398 0.0729 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0353 0.0344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0362 0.0636 0.0588
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0217 0.0208
Entamoeba histolytica protein kinase domain containing protein 0.0264 0.038 0.1887
Giardia lamblia Kinase, AGC PKA 0.0352 0.061 0.1405
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0362 0.0636 0.3353
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0254 0.0352 0.108
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0188 0.018 0.018
Schistosoma mansoni tyrosine kinase 0.0211 0.0241 0.0233
Entamoeba histolytica PH domain containing protein kinase, putative 0.0271 0.0398 0.1986
Schistosoma mansoni hypothetical protein 0.0398 0.0729 0.0721
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0445 0.2259
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0362 0.0636 0.0588
Brugia malayi Protein kinase domain containing protein 0.0433 0.0823 0.0815
Schistosoma mansoni hypothetical protein 0.0184 0.0169 0.016
Loa Loa (eye worm) hypothetical protein 0.0312 0.0505 0.0505
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0159 0.0105 0.0096
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0218 0.0258 0.0209
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0254 0.0353 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.128 0.3924
Loa Loa (eye worm) hypothetical protein 0.0182 0.0163 0.0163
Brugia malayi Prion-like- 0.0182 0.0163 0.0154
Schistosoma mansoni tyrosine kinase 0.0344 0.0589 0.0581
Onchocerca volvulus 0.0398 0.0729 0.3284
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.089 0.0882
Schistosoma mansoni protein kinase 0.0225 0.0277 0.0268
Echinococcus multilocularis dual specificity 0.0312 0.0506 0.0459
Brugia malayi protein kinase C II. 0.0459 0.089 0.0882
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0825 0.1848 0.1848
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0139 0.0051 0.0043
Brugia malayi Protein kinase domain containing protein 0.2118 0.5238 0.5234
Echinococcus granulosus cathepsin b 0.0191 0.0187 0.0138
Toxoplasma gondii casein kinase I 0.0244 0.0327 0.0256
Echinococcus granulosus protein kinase 0.0344 0.0589 0.0543
Brugia malayi Papain family cysteine protease containing protein 0.0139 0.0051 0.0043
Loa Loa (eye worm) hypothetical protein 0.0271 0.0399 0.0399
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0326 0.054 0.0493
Trypanosoma brucei cdc2-related kinase 1 0.0267 0.0387 0.0337
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0456 0.0881 0.0873
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0254 0.0352 0.0303
Plasmodium falciparum amino acid transporter, putative 0.0159 0.0105 0.0054
Entamoeba histolytica PH domain containing protein kinase, putative 0.0369 0.0655 0.346
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0187 0.0177 0.0104
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0362 0.0636 0.0589
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0719 0.1571 0.1571
Echinococcus granulosus cGMP dependent protein kinase 1 0.019 0.0184 0.0135
Echinococcus granulosus cathepsin b 0.0191 0.0187 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0793 0.1765 0.1757
Brugia malayi Protein kinase domain containing protein 0.0187 0.0177 0.0168
Brugia malayi Protein kinase domain containing protein 0.0148 0.0074 0.0065
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1364 0.3261 0.3226
Brugia malayi Protein kinase domain containing protein 0.0345 0.0592 0.0584
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0327 0.0279
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0399 0.0734 0.0725
Plasmodium falciparum NIMA related kinase 1 0.0306 0.0489 0.044
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0528 0.1072 0.1027
Leishmania major hypothetical protein, conserved 0.0362 0.0636 0.0567
Plasmodium vivax apical sushi protein, putative 0.0734 0.1611 0.1568
Echinococcus multilocularis c src tyrosine kinase 0.0211 0.0241 0.0193
Schistosoma mansoni tyrosine kinase 0.0144 0.0064 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0592 0.0584
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0227 0.0281 0.0233
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0264 0.038 0.1887
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0369 0.0654 0.0654
Trypanosoma cruzi NADH dehydrogenase, putative 0.0362 0.0636 0.0628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0163 0.0154
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.042 0.0787 0.0741
Loa Loa (eye worm) hypothetical protein 0.0201 0.0214 0.0214
Loa Loa (eye worm) disorganized muscle protein 1 0.0182 0.0163 0.0163
Schistosoma mansoni protein kinase 0.0193 0.0194 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0148 0.0454
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0344 0.0589 0.0542
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0362 0.0636 0.195
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0793 0.1765 0.1724
Onchocerca volvulus 0.0276 0.0411 0.1823
Brugia malayi Protein kinase domain containing protein 0.0451 0.087 0.0862
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0306 0.0489 0.0419
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0494 0.0981 0.0981
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0326 0.054 0.0493
Trichomonas vaginalis AGC family protein kinase 0.0402 0.0741 0.2273
Schistosoma mansoni tyrosine kinase 0.0211 0.0241 0.0233

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.3 uM Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells. ChEMBL. 7731020
IC50 (binding) = 1.3 uM Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells ChEMBL. 7861414
IC50 (binding) = 1.3 uM Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells. ChEMBL. 7731020
IC50 (binding) = 1.3 uM Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells ChEMBL. 7861414

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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