Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0383 | 0.0383 |
Echinococcus granulosus | aminopeptidase N | 0.0066 | 0.0343 | 0.0343 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0066 | 0.0343 | 1 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0045 | 0.01 |
Brugia malayi | hypothetical protein | 0.0568 | 0.449 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0475 | 0.3723 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0025 | 0.0011 | 0.0319 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0066 | 0.0343 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0218 | 0.0218 |
Brugia malayi | Trypsin family protein | 0.0153 | 0.106 | 0.236 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0025 | 0.0011 | 0.0011 |
Schistosoma mansoni | lamin | 0.0027 | 0.0027 | 0.0027 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0025 | 0.0011 | 0.0011 |
Echinococcus granulosus | enteropeptidase | 0.0153 | 0.106 | 0.106 |
Brugia malayi | jmjC domain containing protein | 0.0156 | 0.109 | 0.2428 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0153 | 0.106 | 0.106 |
Echinococcus multilocularis | aminopeptidase N | 0.0066 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0011 | 0.0011 |
Entamoeba histolytica | aminopeptidase, putative | 0.0066 | 0.0343 | 0.156 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0045 | 0.0045 |
Brugia malayi | Pre-SET motif family protein | 0.006 | 0.0296 | 0.0658 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0045 | 0.01 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0045 | 0.0045 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0128 | 0.0284 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0032 | 0.0087 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0153 | 0.106 | 0.106 |
Trypanosoma brucei | aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0011 | 0.0024 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0066 | 0.0343 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.035 | 0.035 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0066 | 0.0343 | 0.0343 |
Brugia malayi | Peptidase family M1 containing protein | 0.0066 | 0.0343 | 0.0764 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Echinococcus granulosus | Mastin | 0.0153 | 0.106 | 0.106 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0152 | 0.0409 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Loa Loa (eye worm) | trypsin family protein | 0.0153 | 0.106 | 0.106 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0153 | 0.106 | 0.106 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.014 | 0.014 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0025 | 0.0011 | 0.0319 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0058 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0066 | 0.0343 | 0.0343 |
Brugia malayi | TATA binding protein associated factor | 0.0066 | 0.0343 | 0.0764 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0383 | 0.0854 |
Brugia malayi | Peptidase family M1 containing protein | 0.0066 | 0.0343 | 0.0764 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0025 | 0.0011 | 0.0011 |
Schistosoma mansoni | protein phosphatase 2C | 0.0025 | 0.0011 | 0.0011 |
Plasmodium vivax | SET domain protein, putative | 0.006 | 0.0296 | 0.8614 |
Onchocerca volvulus | 0.0031 | 0.0057 | 0.0082 | |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0153 | 0.106 | 0.236 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0086 | 0.0086 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0045 | 0.0045 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0086 | 0.0086 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0027 | 0.0059 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.006 | 0.0296 | 0.0296 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0066 | 0.0343 | 0.0922 |
Brugia malayi | hypothetical protein | 0.0153 | 0.106 | 0.236 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0383 | 0.0383 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0066 | 0.0343 | 0.0343 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0027 | 0.0027 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0011 | 0.0319 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0045 | 0.1307 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0383 | 0.0383 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Mycobacterium ulcerans | hypothetical protein | 0.0153 | 0.106 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0152 | 0.034 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0066 | 0.0343 | 0.0343 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0086 | 0.0191 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1236 | 1 | 1 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0066 | 0.0343 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0066 | 0.0343 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0066 | 0.0343 | 0.0922 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0218 | 0.0218 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0011 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0343 | 0.0343 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0027 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0128 | 0.0343 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0045 | 0.0204 |
Schistosoma mansoni | phd/f-box containing protein | 0.0025 | 0.0011 | 0.0011 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0152 | 0.0409 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0071 | 0.0391 | 0.0391 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0027 | 0.0027 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0066 | 0.0343 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0153 | 0.106 | 0.106 |
Echinococcus multilocularis | Mastin | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0025 | 0.0011 | 0.0011 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0383 | 0.1029 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0057 | 0.0057 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0291 | 0.2199 | 0.5 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0045 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | aminopeptidase N | 0.0066 | 0.0343 | 0.0343 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0383 | 0.0383 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0066 | 0.0343 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0045 | 0.1307 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0296 | 0.0296 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0153 | 0.106 | 0.106 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0011 | 0.0011 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0027 | 0.0059 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | jumonji domain containing protein | 0.0025 | 0.0011 | 0.0011 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0022 | 0.0022 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0066 | 0.0343 | 0.0343 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0156 | 0.109 | 0.109 |
Onchocerca volvulus | 0.0066 | 0.0343 | 0.0856 | |
Echinococcus granulosus | jumonji domain containing 1A | 0.0025 | 0.0011 | 0.0011 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.014 | 0.014 |
Toxoplasma gondii | aminopeptidase N protein | 0.0066 | 0.0343 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0025 | 0.0011 | 0.0319 |
Brugia malayi | Pre-SET motif family protein | 0.0418 | 0.3247 | 0.7232 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0045 | 0.0045 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0045 | 0.1307 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0383 | 0.0383 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0142 | 0.0973 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0011 | 0.0319 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0153 | 0.106 | 0.236 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0128 | 0.0343 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0343 | 0.0764 |
Plasmodium vivax | JmjC domain containing protein | 0.0025 | 0.0011 | 0.0319 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0011 | 0.0024 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0218 | 0.1602 | 0.1602 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0156 | 0.109 | 0.109 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0296 | 0.0296 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.0973 | 0.8787 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0045 | 0.0045 |
Onchocerca volvulus | 0.0066 | 0.0343 | 0.0856 | |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0025 | 0.0011 | 0.0011 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Onchocerca volvulus | 0.0475 | 0.3723 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0343 | 0.0343 |
Echinococcus multilocularis | enteropeptidase | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0025 | 0.0011 | 0.0011 |
Brugia malayi | Trypsin family protein | 0.0153 | 0.106 | 0.236 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0291 | 0.2199 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1236 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0095 | 0.0587 | 0.0587 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0025 | 0.0011 | 0.0011 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0095 | 0.0587 | 0.0587 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0066 | 0.0343 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0011 | 0.0319 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0587 | 0.1308 |
Brugia malayi | Trypsin family protein | 0.0153 | 0.106 | 0.236 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Echinococcus granulosus | peregrin | 0.003 | 0.0045 | 0.0045 |
Echinococcus granulosus | phd:f box containing protein | 0.0025 | 0.0011 | 0.0011 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.0343 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.006 | 0.0296 | 0.8614 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0025 | 0.0011 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0032 | 0.0087 |
Schistosoma mansoni | lamin | 0.0027 | 0.0027 | 0.0027 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0027 | 0.0027 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0027 | 0.0027 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0045 | 0.1307 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0066 | 0.0343 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0418 | 0.3247 | 0.3247 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0296 | 0.0296 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0153 | 0.106 | 0.106 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0066 | 0.0343 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.006 | 0.0296 | 0.0296 |
Onchocerca volvulus | 0.0066 | 0.0343 | 0.0856 | |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.0343 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0011 | 0.0024 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0587 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | lamin | 0.0027 | 0.0027 | 0.0027 |
Echinococcus multilocularis | phd:f box containing protein | 0.0025 | 0.0011 | 0.0011 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0066 | 0.0343 | 1 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0025 | 0.0011 | 0.0011 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.006 | 0.0296 | 0.0296 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.2199 | 0.5907 |
Schistosoma mansoni | jumonji domain containing protein | 0.0136 | 0.0926 | 0.0926 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0383 | 0.1029 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0095 | 0.0587 | 0.0587 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Onchocerca volvulus | 0.0153 | 0.106 | 0.2795 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0587 | 0.0587 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0218 | 0.0485 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0128 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0128 | 0.0128 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1236 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0027 | 0.0027 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0153 | 0.106 | 0.106 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0066 | 0.0343 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.0973 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0218 | 0.0485 |
Brugia malayi | Trypsin family protein | 0.0153 | 0.106 | 0.236 |
Onchocerca volvulus | 0.0071 | 0.0391 | 0.0985 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0153 | 0.106 | 0.106 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0066 | 0.0343 | 0.0343 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0025 | 0.0011 | 0.0319 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0343 | 0.0764 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0066 | 0.0343 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0066 | 0.0343 | 0.0764 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.106 | 0.106 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0304 | 0.0304 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.0343 | 0.0343 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.11 uM | In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assay | ChEMBL. | 10890162 |
IC50 (binding) | = 3.3 uM | In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellum | ChEMBL. | 10890162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.