Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0105 | 0.1121 | 0.3491 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0085 | 0.0107 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0156 | 0.1768 | 0.1765 |
Brugia malayi | nuclear receptor NHR-88 | 0.0073 | 0.0726 | 0.0942 |
Echinococcus granulosus | dual specificity | 0.0105 | 0.1121 | 0.1116 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0214 | 0.0278 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0156 | 0.1768 | 0.2342 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0238 | 0.3628 |
Brugia malayi | RNA, U transporter 1 | 0.0088 | 0.0911 | 0.1189 |
Schistosoma mansoni | endoplasmin | 0.0062 | 0.0582 | 0.0577 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.0657 | 0.0851 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0238 | 0.0491 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0073 | 0.0726 | 0.0942 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.917 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0062 | 0.0582 | 0.1755 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0073 | 0.0726 | 0.0721 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0022 | 0.0079 | 0.0301 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0022 | 0.0079 | 0.0301 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0012 | 0.001 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0156 | 0.1768 | 0.1765 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0436 | 0.0432 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0084 | 0.0105 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0156 | 0.1768 | 0.1765 |
Echinococcus multilocularis | heat shock protein 90 | 0.0062 | 0.0582 | 0.0577 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0036 | 0.0031 |
Schistosoma mansoni | thyroid hormone receptor | 0.0291 | 0.349 | 0.3487 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.4636 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.001 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0031 | 0.0187 | 0.0183 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0238 | 0.055 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0037 | 0.0033 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0156 | 0.1768 | 0.1765 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0463 | 0.1372 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0073 | 0.0726 | 0.0721 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0156 | 0.1768 | 0.1765 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.0538 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0037 | 0.0033 |
Trypanosoma cruzi | heat shock protein, putative | 0.0049 | 0.0419 | 0.123 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0156 | 0.1768 | 0.1765 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0156 | 0.1768 | 0.2329 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0237 | 0.0232 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0436 | 0.0432 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0023 | 0.0084 | 0.0079 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0073 | 0.0726 | 0.0957 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0022 | 0.0079 | 0.0301 |
Echinococcus multilocularis | lamin | 0.0057 | 0.0522 | 0.0518 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Onchocerca volvulus | 0.0156 | 0.1768 | 1 | |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0805 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0022 | 0.0079 | 0.0301 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.053 | 0.0525 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0022 | 0.0079 | 0.0301 |
Echinococcus multilocularis | musashi | 0.0057 | 0.0522 | 0.0518 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0084 | 0.0149 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0238 | 0.391 |
Schistosoma mansoni | lamin | 0.0057 | 0.0522 | 0.0518 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.1959 | 0.2595 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0022 | 0.0079 | 0.0301 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1212 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0139 | 0.0329 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0238 | 0.0646 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0057 | 0.0522 | 0.0672 |
Brugia malayi | Protein kinase domain containing protein | 0.0105 | 0.1121 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0156 | 0.1768 | 0.1765 |
Plasmodium vivax | importin-beta 2, putative | 0.0031 | 0.0187 | 0.0427 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0156 | 0.1768 | 0.1765 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0156 | 0.1768 | 0.1765 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0022 | 0.0079 | 0.0301 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.042 | 0.0416 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0156 | 0.1768 | 0.1765 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0082 | 0.0837 | 0.1106 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.917 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0036 | 0.0031 |
Plasmodium vivax | heat shock protein, putative | 0.0341 | 0.4124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0063 | 0.059 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0022 | 0.0079 | 0.0134 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0022 | 0.0079 | 0.0301 |
Schistosoma mansoni | thyroid hormone receptor | 0.0291 | 0.349 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0085 | 0.0107 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.0492 | 0.8219 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0073 | 0.0726 | 0.0721 |
Brugia malayi | follicle stimulating hormone receptor | 0.0474 | 0.5813 | 0.7708 |
Echinococcus granulosus | geminin | 0.0544 | 0.6694 | 0.6693 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0463 | 0.0459 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0726 | 0.0942 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0085 | 0.127 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0085 | 0.0107 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0079 | 0.0099 |
Leishmania major | squalene monooxygenase-like protein | 0.0264 | 0.314 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0085 | 0.127 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0175 | 0.202 | 0.2016 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0072 | 0.0068 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0156 | 0.1768 | 0.1765 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.042 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0837 | 0.1106 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0238 | 0.0293 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0049 | 0.0419 | 0.1983 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0037 | 0.0043 |
Echinococcus granulosus | heat shock protein 90 | 0.0062 | 0.0582 | 0.0577 |
Schistosoma mansoni | lamin | 0.0057 | 0.0522 | 0.0518 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0463 | 0.1372 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.016 | 0.1822 | 0.24 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0264 | 0.314 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.0062 | 0.0582 | 0.1386 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.042 | 0.0552 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.3029 | 0.4015 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0085 | 0.0408 |
Brugia malayi | small heat shock protein | 0.061 | 0.7536 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.042 | 0.0416 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0085 | 0.0154 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0474 | 0.5813 | 0.7712 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0238 | 0.0906 |
Schistosoma mansoni | coup transcription factor | 0.0156 | 0.1768 | 0.1765 |
Trichomonas vaginalis | heat shock protein, putative | 0.0063 | 0.059 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0463 | 0.0459 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0139 | 0.0162 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0079 | 0.0082 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0463 | 0.1372 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.0657 | 0.0851 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.0492 | 0.0487 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0238 | 0.0646 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0073 | 0.0726 | 0.0721 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0082 | 0.0837 | 0.1091 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0113 | 0.0645 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0463 | 0.7701 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0084 | 0.0175 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0238 | 0.031 |
Onchocerca volvulus | 0.0057 | 0.0522 | 0.2597 | |
Toxoplasma gondii | heat shock protein HSP90 | 0.0062 | 0.0582 | 0.1332 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0073 | 0.0726 | 0.0721 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0112 | 0.1212 | 0.1208 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0085 | 0.009 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.917 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0012 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0156 | 0.1768 | 0.2329 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Echinococcus multilocularis | lamin dm0 | 0.0057 | 0.0522 | 0.0518 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0113 | 0.1371 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0156 | 0.1768 | 0.1765 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0156 | 0.1768 | 0.1765 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0136 | 0.1516 | 0.1512 |
Brugia malayi | bZIP transcription factor family protein | 0.0175 | 0.202 | 0.2663 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0238 | 0.3628 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.0574 | 0.0569 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0057 | 0.0522 | 0.0688 |
Schistosoma mansoni | ran | 0.0023 | 0.0084 | 0.0079 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.0436 | 0.0432 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0156 | 0.1768 | 0.2329 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0022 | 0.0079 | 0.0301 |
Schistosoma mansoni | nuclear hormone receptor | 0.0073 | 0.0726 | 0.0721 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0084 | 0.0839 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0073 | 0.0726 | 0.0942 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0022 | 0.0079 | 0.1161 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0079 | 0.0082 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0112 | 0.1212 | 0.1208 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0463 | 0.1372 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0049 | 0.0419 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0665 | 0.0877 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0082 | 0.0837 | 0.1091 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0156 | 0.1768 | 0.1765 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0037 | 0.0062 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0101 | 0.0112 |
Echinococcus granulosus | importin subunit beta 1 | 0.0031 | 0.0187 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0022 | 0.0079 | 0.0301 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0023 | 0.0084 | 0.0113 |
Brugia malayi | RNA binding protein | 0.0068 | 0.0657 | 0.0851 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0156 | 0.1768 | 0.2342 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0136 | 0.1516 | 0.1512 |
Schistosoma mansoni | intermediate filament proteins | 0.0057 | 0.0522 | 0.0518 |
Schistosoma mansoni | nuclear receptor | 0.0073 | 0.0726 | 0.0721 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0238 | 0.0646 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0022 | 0.0079 | 0.0301 |
Brugia malayi | nuclear hormone receptor | 0.0156 | 0.1768 | 0.2329 |
Schistosoma mansoni | ran | 0.0023 | 0.0084 | 0.0079 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0238 | 0.0906 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0805 | 1 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0105 | 0.1121 | 0.1482 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0156 | 0.1768 | 0.2342 |
Brugia malayi | Cytochrome P450 family protein | 0.0082 | 0.084 | 0.1094 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0022 | 0.0079 | 0.0134 |
Entamoeba histolytica | hypothetical protein | 0.0105 | 0.1121 | 0.9224 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0657 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | conserved hypotetical protein | 0.0073 | 0.0726 | 0.0942 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0139 | 0.031 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0073 | 0.0726 | 0.0942 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0139 | 0.0329 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0185 | 0.0239 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0156 | 0.1768 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0156 | 0.1768 | 0.2342 |
Trichomonas vaginalis | endoplasmin, putative | 0.0049 | 0.0411 | 0.6755 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0073 | 0.0726 | 0.0957 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0037 | 0.0142 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0082 | 0.0837 | 0.0833 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0022 | 0.0079 | 0.0301 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0657 | 0.0653 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0463 | 0.1372 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.0657 | 0.0653 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0436 | 0.0432 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0022 | 0.0079 | 0.1161 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0264 | 0.314 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0542 | 0.0538 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0837 | 0.1106 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0022 | 0.0079 | 0.1161 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0022 | 0.0079 | 0.0301 |
Brugia malayi | ecdysteroid receptor | 0.0156 | 0.1768 | 0.2329 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0255 | 0.3029 | 0.3025 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0073 | 0.0726 | 0.0721 |
Treponema pallidum | heat shock protein 90 | 0.0063 | 0.059 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0073 | 0.0726 | 0.0942 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0238 | 0.3628 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0062 | 0.0582 | 0.1755 |
Echinococcus granulosus | snurportin 1 | 0.033 | 0.3986 | 0.3983 |
Brugia malayi | Hsp90 protein | 0.0049 | 0.0419 | 0.0534 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0726 | 0.0942 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0156 | 0.1768 | 0.1765 |
Entamoeba histolytica | protein kinase, putative | 0.0105 | 0.1121 | 0.9224 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0022 | 0.0079 | 0.0134 |
Echinococcus multilocularis | dual specificity | 0.0105 | 0.1121 | 0.1116 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0463 | 0.1372 |
Schistosoma mansoni | nuclear receptor | 0.0073 | 0.0726 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0837 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0139 | 0.0179 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.0436 | 0.0557 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Echinococcus granulosus | intermediate filament protein | 0.0057 | 0.0522 | 0.0518 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0156 | 0.1768 | 0.2329 |
Echinococcus multilocularis | 0.0022 | 0.0079 | 0.0074 | |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Loa Loa (eye worm) | endoplasmin | 0.0062 | 0.0582 | 0.0766 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0463 | 0.7701 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0238 | 0.0906 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0156 | 0.1768 | 0.1765 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0238 | 0.0906 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.1603 | 0.1599 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0436 | 0.0432 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0238 | 0.391 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0146 | 0.0141 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0238 | 0.0906 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0022 | 0.0079 | 0.1161 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.0657 | 0.0866 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0073 | 0.0726 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0509 | 0.067 |
Onchocerca volvulus | 0.0073 | 0.0726 | 0.3805 | |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0073 | 0.0726 | 0.0721 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0246 | 0.3774 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0238 | 0.031 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.001 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0022 | 0.0079 | 0.1161 |
Onchocerca volvulus | 0.0035 | 0.0238 | 0.0907 | |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0062 | 0.0582 | 0.1755 |
Trypanosoma brucei | squalene monooxygenase, putative | 0.0264 | 0.314 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0837 | 0.1106 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0062 | 0.0582 | 0.1755 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.001 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.1332 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.0657 | 0.0653 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1212 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0246 | 0.3774 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0049 | 0.0044 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0139 | 0.0329 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0049 | 0.0419 | 0.055 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0022 | 0.0079 | 0.1161 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0037 | 0.0033 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0156 | 0.1768 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.016 | 0.1822 | 0.24 |
Schistosoma mansoni | nuclear hormone receptor | 0.0073 | 0.0726 | 0.0721 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0156 | 0.1768 | 0.2329 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0238 | 0.0293 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0105 | 0.1121 | 0.3491 |
Brugia malayi | hypothetical protein | 0.0082 | 0.0837 | 0.1091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0657 | 0.0653 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0436 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0022 | 0.0079 | 0.0074 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0072 | 0.0068 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0291 | 0.349 | 0.3487 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0073 | 0.0726 | 0.0957 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0156 | 0.1768 | 0.1765 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0022 | 0.0079 | 0.0134 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0238 | 0.391 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0082 | 0.0837 | 0.0833 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0063 | 0.059 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0238 | 0.311 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0079 | 0.0074 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0463 | 0.0459 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0238 | 0.3628 |
Plasmodium falciparum | heat shock protein 90 | 0.0062 | 0.0582 | 0.1386 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.042 | 0.0416 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0492 | 0.1464 |
Schistosoma mansoni | heat shock protein | 0.0062 | 0.0582 | 0.0577 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0156 | 0.1768 | 0.1765 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0085 | 0.0123 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0718 | 0.0932 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0238 | 0.0906 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0082 | 0.0837 | 0.0833 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0238 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1822 | 0.2412 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0185 | 0.0222 |
Echinococcus multilocularis | geminin | 0.0544 | 0.6694 | 0.6693 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0105 | 0.1121 | 0.9224 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0156 | 0.1768 | 0.2329 |
Brugia malayi | hypothetical protein | 0.0082 | 0.0837 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0133 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Brugia malayi | hypothetical protein | 0.0138 | 0.1542 | 0.2028 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0156 | 0.1768 | 0.1765 |
Schistosoma mansoni | heat shock protein | 0.0062 | 0.0582 | 0.0577 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0022 | 0.0079 | 0.1161 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0463 | 0.0459 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.033 | 0.3986 | 0.5286 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0238 | 0.0293 |
Onchocerca volvulus | 0.0052 | 0.0454 | 0.2193 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0085 | 0.009 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0322 | 0.0318 |
Loa Loa (eye worm) | intermediate filament protein | 0.0057 | 0.0522 | 0.0688 |
Schistosoma mansoni | importin beta-1 | 0.0031 | 0.0187 | 0.0183 |
Plasmodium falciparum | importin beta, putative | 0.0031 | 0.0187 | 0.0427 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0454 | 0.0581 |
Echinococcus granulosus | FTZ F1 alpha | 0.0156 | 0.1768 | 0.1765 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0156 | 0.1768 | 0.2329 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0156 | 0.1768 | 0.1765 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0238 | 0.0906 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0436 | 0.0432 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0238 | 0.0293 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0237 | 0.0232 |
Entamoeba histolytica | protein kinase, putative | 0.0105 | 0.1121 | 0.9224 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0022 | 0.0079 | 0.0134 |
Echinococcus granulosus | lamin | 0.0057 | 0.0522 | 0.0518 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0133 | 0.017 |
Brugia malayi | Importin beta-1 subunit | 0.0031 | 0.0187 | 0.0226 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0036 | 0.0031 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | jun protein | 0.0175 | 0.202 | 0.2016 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1108 | 0.1465 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0238 | 0.311 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0109 | 0.118 | 0.1547 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0041 | 0.0321 | 0.0751 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.0492 | 0.0487 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0483 | 0.0479 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0023 | 0.0084 | 0.0175 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0022 | 0.0079 | 0.0301 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0463 | 0.1042 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0454 | 0.045 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0022 | 0.0079 | 0.1161 |
Onchocerca volvulus | 0.0035 | 0.0238 | 0.0907 | |
Trypanosoma brucei | cytochrome P450, putative | 0.0022 | 0.0079 | 0.0134 |
Brugia malayi | nuclear receptor RXR | 0.0082 | 0.0837 | 0.1091 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0022 | 0.0079 | 0.0301 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.1755 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.1755 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.042 | 0.0536 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0049 | 0.0419 | 0.325 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.0278 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Onchocerca volvulus | 0.0138 | 0.1542 | 0.8655 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0085 | 0.0408 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0238 | 0.391 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.032 | 0.0418 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0038 | 0.0278 | 0.0273 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.1121 | 0.1116 |
Leishmania major | GTP-binding protein, putative | 0.0023 | 0.0084 | 0.0149 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0055 | 0.0492 | 0.0487 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0084 | 0.0149 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0156 | 0.1768 | 1 |
Plasmodium falciparum | endoplasmin, putative | 0.0049 | 0.0411 | 0.097 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0657 | 0.0653 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0105 | 0.1121 | 0.3491 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0073 | 0.0726 | 0.0942 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0022 | 0.0079 | 0.1161 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.042 | 0.0416 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0038 | 0.0278 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0073 | 0.0726 | 0.3805 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.0079 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0146 | 0.0188 |
Schistosoma mansoni | jun-related protein | 0.0143 | 0.1603 | 0.1599 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.0436 | 0.0573 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0063 | 0.059 | 0.1782 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0463 | 0.0459 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0022 | 0.0079 | 0.1161 |
Leishmania major | heat shock protein, putative | 0.0049 | 0.0419 | 0.123 |
Echinococcus multilocularis | snurportin 1 | 0.033 | 0.3986 | 0.3983 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0238 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.118 | 0.1561 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0139 | 0.031 |
Schistosoma mansoni | hypothetical protein | 0.033 | 0.3986 | 0.3983 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0341 | 0.4124 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0238 | 0.0906 |
Brugia malayi | heat shock protein 90 | 0.0062 | 0.0582 | 0.0751 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0021 | 0.0056 | 0.006 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0049 | 0.0419 | 0.123 |
Schistosoma mansoni | hypothetical protein | 0.0544 | 0.6694 | 0.6693 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0156 | 0.1768 | 0.2329 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0238 | 0.0906 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0022 | 0.0079 | 0.0301 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0156 | 0.1768 | 0.1765 |
Brugia malayi | hypothetical protein | 0.0112 | 0.1212 | 0.1589 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0238 | 0.0906 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0012 | 0.0045 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0085 | 0.0154 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0156 | 0.1768 | 0.2329 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0156 | 0.1768 | 0.1765 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0238 | 0.0233 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0341 | 0.4124 | 1 |
Brugia malayi | tailless protein | 0.0073 | 0.0726 | 0.0942 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | heat shock protein | 0.0062 | 0.0582 | 0.0577 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.053 | 0.0525 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.0436 | 0.0432 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0085 | 0.0123 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.2626 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0156 | 0.1768 | 0.2329 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0085 | 0.127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0156 | 0.1768 | 0.2342 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0156 | 0.1768 | 0.2329 |
Trichomonas vaginalis | heat shock protein, putative | 0.0063 | 0.059 | 1 |
Onchocerca volvulus | 0.0057 | 0.0522 | 0.2597 | |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | endoplasmin | 0.0063 | 0.059 | 0.0586 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.1235 |
Schistosoma mansoni | cytochrome P450 | 0.0022 | 0.0079 | 0.0074 |
Loa Loa (eye worm) | DR-78 | 0.0073 | 0.0726 | 0.0957 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0542 | 0.0538 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0156 | 0.1768 | 0.2342 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0073 | 0.0726 | 0.3805 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0542 | 0.1627 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.0079 | 0.0134 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.0079 | 0.0134 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0062 | 0.0582 | 0.0766 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Brugia malayi | nuclear hormone receptor | 0.0073 | 0.0726 | 0.0942 |
Trichomonas vaginalis | ran, putative | 0.0023 | 0.0084 | 0.0839 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0085 | 0.127 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0037 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0296 | 0.0387 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0657 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0022 | 0.0079 | 0.0301 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0146 | 0.0141 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0037 | 0.0062 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0113 | 0.0244 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0085 | 0.127 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0187 | 0.0483 |
Trichomonas vaginalis | heat shock protein, putative | 0.0041 | 0.0321 | 0.5125 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0139 | 0.031 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0085 | 0.127 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0266 | 0.0331 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0085 | 0.0325 |
Trichomonas vaginalis | heat shock protein, putative | 0.0049 | 0.0411 | 0.6755 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0156 | 0.1768 | 0.2329 |
Loa Loa (eye worm) | cytochrome P450 | 0.0022 | 0.0079 | 0.0099 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0238 | 0.0233 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.016 | 0.1822 | 0.2412 |
Brugia malayi | steroid hormone receptor | 0.0156 | 0.1768 | 0.2329 |
Giardia lamblia | Grp94/Hsp90 | 0.0063 | 0.059 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0187 | 0.0483 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0463 | 0.0593 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0072 | 0.0068 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0022 | 0.0079 | 0.0301 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0105 | 0.1121 | 0.3491 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0522 | 0.0688 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0079 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0255 | 0.3029 | 0.4005 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0062 | 0.0582 | 0.985 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0022 | 0.0079 | 0.1161 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0038 | 0.0278 | 0.0346 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0238 | 0.391 |
Schistosoma mansoni | nuclear hormone receptor | 0.0156 | 0.1768 | 0.1765 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0022 | 0.0079 | 0.0102 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0463 | 0.7701 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.0492 | 0.1464 |
Brugia malayi | intermediate filament protein | 0.0057 | 0.0522 | 0.0672 |
Plasmodium vivax | endoplasmin, putative | 0.0062 | 0.0582 | 0.1386 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0022 | 0.0079 | 0.1161 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.0657 | 0.0866 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0139 | 0.0329 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0073 | 0.0726 | 0.0721 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0322 | 0.0318 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0156 | 0.1768 | 0.1765 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0049 | 0.0419 | 0.0415 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0085 | 0.0154 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0156 | 0.1768 | 0.2329 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus granulosus | endoplasmin | 0.0063 | 0.059 | 0.0586 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0049 | 0.0059 |
Echinococcus granulosus | jun protein | 0.0175 | 0.202 | 0.2016 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.2065 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0113 | 0.1371 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0049 | 0.0419 | 0.0415 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0156 | 0.1768 | 0.2329 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0463 | 0.1372 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.042 | 0.0416 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0156 | 0.1768 | 0.2342 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0238 | 0.0646 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0023 | 0.0084 | 0.0079 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0454 | 0.045 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0063 | 0.059 | 0.2247 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0156 | 0.1768 | 0.2329 |
Plasmodium vivax | heat shock protein 90, putative | 0.0049 | 0.0419 | 0.099 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0113 | 0.1371 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0073 | 0.0726 | 0.0942 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1212 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0463 | 0.7701 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0022 | 0.0079 | 0.1161 |
Brugia malayi | cytochrome P450 | 0.0022 | 0.0079 | 0.0082 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0156 | 0.1768 | 0.2329 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0063 | 0.059 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0113 | 0.0244 |
Onchocerca volvulus | 0.0073 | 0.0726 | 0.3805 | |
Trichomonas vaginalis | heat shock protein, putative | 0.0062 | 0.0582 | 0.985 |
Brugia malayi | nuclear receptor NHR-67 | 0.0073 | 0.0726 | 0.0942 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.118 | 0.1176 |
Schistosoma mansoni | hypothetical protein | 0.0544 | 0.6694 | 0.6693 |
Loa Loa (eye worm) | hypothetical protein | 0.061 | 0.7536 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0463 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.0492 | 0.8219 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0085 | 0.127 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0542 | 0.0538 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0085 | 0.009 |
Brugia malayi | ecdysone receptor | 0.0073 | 0.0726 | 0.0942 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.0436 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0436 | 0.0573 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0022 | 0.0079 | 0.1161 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0463 | 0.1372 |
Schistosoma mansoni | hypothetical protein | 0.0136 | 0.1516 | 0.1512 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0156 | 0.1768 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1108 | 0.1465 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0079 | 0.0099 |
Trypanosoma brucei | heat shock protein, putative | 0.0062 | 0.0582 | 0.1755 |
Entamoeba histolytica | Ran family GTPase | 0.0023 | 0.0084 | 0.0395 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0436 | 0.0432 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.042 | 0.0416 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0073 | 0.0726 | 0.0942 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.1212 | 0.1208 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0112 | 0.1212 | 0.1208 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0062 | 0.0582 | 0.4636 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0238 | 0.031 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0082 | 0.0837 | 0.0833 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.0079 | 0.0134 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0085 | 0.0408 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0022 | 0.0079 | 0.0301 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.1212 | 1 |
Schistosoma mansoni | heat shock protein | 0.0049 | 0.0419 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0837 | 0.1106 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0037 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1768 | 0.2342 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0175 | 0.202 | 0.2016 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.0079 | 0.0134 |
Onchocerca volvulus | 0.0035 | 0.0238 | 0.0907 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.001 |
Leishmania major | heat shock protein 83-1 | 0.0062 | 0.0582 | 0.1755 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0238 | 0.3628 |
Schistosoma mansoni | endoplasmin | 0.0062 | 0.0582 | 0.0577 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0022 | 0.0079 | 0.1161 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0022 | 0.0079 | 0.1161 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0436 | 0.0432 |
Brugia malayi | Endoplasmin precursor | 0.0062 | 0.0582 | 0.0751 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0139 | 0.025 |
Echinococcus granulosus | lamin dm0 | 0.0057 | 0.0522 | 0.0518 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0187 | 0.0243 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0085 | 0.0325 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0082 | 0.084 | 0.1109 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.0657 | 0.0866 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0037 | 0.0441 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0084 | 0.0149 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0085 | 0.127 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0031 | 0.0187 | 0.0367 |
Echinococcus granulosus | heat shock protein | 0.0062 | 0.0582 | 0.0577 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0022 | 0.0079 | 0.0099 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0156 | 0.1768 | 0.2329 |
Schistosoma mansoni | zinc finger protein | 0.0073 | 0.0726 | 0.0721 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0156 | 0.1768 | 0.1765 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0156 | 0.1768 | 0.1765 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0022 | 0.0079 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0726 | 0.0957 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0238 | 0.3628 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0463 | 0.7701 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0073 | 0.0726 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0267 | 0.0348 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0255 | 0.3029 | 0.3025 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.001 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
HD50 (functional) | = 20 mg kg-1 | Hypnotic activity was measured as dose which causes loss of righting reflex for a minimum period of 30s in 50% of mice; Range is 20-30 | ChEMBL. | 7452689 |
HD50 (functional) | = 20 mg kg-1 | Hypnotic activity was measured as dose which causes loss of righting reflex for a minimum period of 30s in 50% of mice; Range is 20-30 | ChEMBL. | 7452689 |
LD50 (ADMET) | = 100 mg kg-1 | Acute toxicity measured as median lethal dose in mice | ChEMBL. | 7452689 |
LD50 (ADMET) | = 100 mg kg-1 | Acute toxicity measured as median lethal dose in mice | ChEMBL. | 7452689 |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.