Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, CMGC MAPK | 0.0123 | 0.1362 | 0.3574 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0115 | 0.0094 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0039 | 0.0158 | 0.0347 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0039 | 0.0158 | 0.0347 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0599 | 0.0579 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.0687 | 0.0667 |
Onchocerca volvulus | 0.0031 | 0.0042 | 0.0033 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0109 | 0.0088 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0039 | 0.0158 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0561 | 0.0541 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0258 | 0.0237 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0115 | 0.0184 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.0967 | 0.0947 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0048 | 0.0027 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0162 | 0.026 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0123 | 0.1362 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0143 | 0.164 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0039 | 0.0158 | 0.0137 |
Entamoeba histolytica | aminopeptidase, putative | 0.0039 | 0.0158 | 0.0118 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0048 | 0.0027 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0109 | 0.0161 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0729 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0162 | 0.0141 |
Brugia malayi | Pre-SET motif family protein | 0.0409 | 0.544 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0599 | 0.0579 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0039 | 0.0158 | 0.0253 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0039 | 0.0158 | 0.1021 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0039 | 0.0158 | 1 |
Brugia malayi | hypothetical protein | 0.0335 | 0.4385 | 0.8053 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0059 | 0.0443 | 0.0422 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0464 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0048 | 0.0027 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | Pre-SET motif family protein | 0.0059 | 0.0443 | 0.0778 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0258 | 0.0237 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0123 | 0.1362 | 0.1343 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0039 | 0.0158 | 0.0253 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0184 | 0.0163 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0039 | 0.0158 | 0.0347 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0258 | 0.0436 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0039 | 0.0158 | 0.0283 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0039 | 0.0158 | 0.0347 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0115 | 0.0698 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0039 | 0.0158 | 0.0347 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.1003 | 0.0984 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0292 | 0.3771 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0967 | 0.1744 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0205 | 0.0295 |
Brugia malayi | MAP kinase sur-1 | 0.0123 | 0.1362 | 0.2473 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.0967 | 0.0947 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.0599 | 0.0579 |
Onchocerca volvulus | 0.0039 | 0.0158 | 0.022 | |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0143 | 0.164 | 1 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0729 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0115 | 0.0094 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0123 | 0.1362 | 0.1343 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0039 | 0.0158 | 0.0347 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0561 | 0.0541 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0039 | 0.0158 | 0.0347 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0561 | 0.0996 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0158 | 0.0252 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0039 | 0.0158 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0048 | 0.0027 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0123 | 0.1362 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0599 | 0.0579 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0599 | 0.0959 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0158 | 0.0252 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0115 | 0.0094 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0115 | 0.0184 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0048 | 0.0049 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0048 | 0.0049 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0123 | 0.1362 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0039 | 0.0158 | 0.0253 |
Onchocerca volvulus | 0.0039 | 0.0158 | 0.022 | |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0109 | 0.0088 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0258 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0158 | 0.0137 |
Onchocerca volvulus | 0.0465 | 0.6246 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0123 | 0.1362 | 0.218 |
Plasmodium vivax | SET domain protein, putative | 0.0059 | 0.0443 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0123 | 0.1362 | 0.1343 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0109 | 0.0088 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0599 | 0.0579 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0048 | 0.0027 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0039 | 0.0158 | 0.0283 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0115 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0292 | 0.3771 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0123 | 0.1362 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0115 | 0.0094 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.1003 | 0.1812 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0039 | 0.0158 | 0.0137 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0258 | 0.0237 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0039 | 0.0158 | 0.0347 |
Trichomonas vaginalis | set domain proteins, putative | 0.0465 | 0.6246 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0599 | 0.0959 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0123 | 0.1362 | 0.1343 |
Echinococcus granulosus | aminopeptidase N | 0.0039 | 0.0158 | 0.0137 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | Peptidase family M1 containing protein | 0.0039 | 0.0158 | 0.0252 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0123 | 0.1362 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0039 | 0.0158 | 0.3247 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0443 | 0.0422 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0115 | 0.0094 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0039 | 0.0158 | 0.0347 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0123 | 0.1362 | 0.218 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0123 | 0.1362 | 0.218 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0115 | 0.0184 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0443 | 0.0422 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0039 | 0.0158 | 0.0347 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0039 | 0.0158 | 0.0137 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0599 | 0.0579 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0412 | 0.0391 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0059 | 0.0443 | 0.0422 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0599 | 0.0579 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0039 | 0.0158 | 0.0347 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0443 | 0.0422 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0258 | 0.0237 |
Onchocerca volvulus | 0.007 | 0.0605 | 0.0938 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Echinococcus multilocularis | aminopeptidase N | 0.0039 | 0.0158 | 0.0137 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0184 | 0.0163 |
Onchocerca volvulus | 0.0039 | 0.0158 | 0.022 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.007 | 0.0605 | 0.0585 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0123 | 0.1362 | 0.1343 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0205 | 0.0328 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0039 | 0.0158 | 0.0347 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0143 | 0.164 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0123 | 0.1362 | 0.218 |
Brugia malayi | TATA binding protein associated factor | 0.0039 | 0.0158 | 0.0252 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0162 | 0.026 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.0599 | 0.1066 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0109 | 0.0088 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.1003 | 0.1812 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0059 | 0.0443 | 0.0422 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0039 | 0.0158 | 0.0137 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0048 | 0.0027 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0039 | 0.0158 | 0.0347 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0048 | 0.0027 |
Toxoplasma gondii | aminopeptidase N protein | 0.0039 | 0.0158 | 0.1021 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0048 | 0.0027 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0205 | 0.0328 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0409 | 0.544 | 0.543 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0123 | 0.1362 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0059 | 0.0443 | 0.3144 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0048 | 0.0027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0258 | 0.0237 |
Trypanosoma brucei | protein kinase, putative | 0.0123 | 0.1362 | 1 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0039 | 0.0158 | 0.0137 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0162 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0318 | 0.0297 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0039 | 0.0158 | 0.3247 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0109 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0048 | 0.0027 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0048 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0042 | 0.0021 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0162 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0115 | 0.0173 |
Brugia malayi | Peptidase family M1 containing protein | 0.0039 | 0.0158 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1003 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0048 | 0.0027 |
Trypanosoma brucei | aminopeptidase, putative | 0.0039 | 0.0158 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0158 | 0.0137 |
Brugia malayi | Peptidase family M1 containing protein | 0.0039 | 0.0158 | 0.0252 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0258 | 0.0237 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0039 | 0.0158 | 0.0137 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0039 | 0.0158 | 0.1021 |
Loa Loa (eye worm) | aminopeptidase N | 0.0039 | 0.0158 | 0.0137 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0039 | 0.0158 | 0.0347 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0123 | 0.1362 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0258 | 0.0237 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0123 | 0.1362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0443 | 0.0422 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0123 | 0.1362 | 0.1343 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0729 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 0.3771 | 0.6037 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | < 1 ug ml-1 | Antifungal activity against Trychophyton rubrum | ChEMBL. | 7310813 |
Inhibition (functional) | = 1 ug ml-1 | Antibacterial activity against Erysipelothrix insidiosa | ChEMBL. | 7310813 |
Inhibition (functional) | = 1 ug ml-1 | Antibacterial activity against Streptococcus pyogenes | ChEMBL. | 7310813 |
Inhibition (functional) | = 10 ug ml-1 | Antifungal activity against Microsporum canis | ChEMBL. | 7310813 |
Inhibition (functional) | = 10 ug ml-1 | Antifungal activity against Trychophyton mentagrophytes | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Phialophora verrucosa | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Cryptococcus neoformans | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Candida tropicalis | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Candida albicans | ChEMBL. | 7310813 |
Inhibition (functional) | = 100 ug ml-1 | Antifungal activity against Mucor species | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Aspergillus fumigatus | ChEMBL. | 7310813 |
Inhibition (functional) | = 100 ug ml-1 | Antifungal activity against Sporothrix schenck ii | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Saprolegnia species | ChEMBL. | 7310813 |
Inhibition (functional) | = 100 ug ml-1 | Antibacterial against Staphylococcus hemolyticus | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Cryptococcus neoformans | ChEMBL. | 7310813 |
Inhibition (functional) | > 100 ug ml-1 | Antifungal activity against Candida albicans | ChEMBL. | 7310813 |
Ratio (functional) | = 0 | Ratio of animals cured to that of animals infected, tested in vivo for antifungal activity against cutaneous candidosis in guinea pig; 0/2 | ChEMBL. | 7310813 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.