Detailed information for compound 36874

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 461.422 | Formula: C21H23N3O9
  • H donors: 5 H acceptors: 9 LogP: 0.5 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN([C@@H]1C(=O)C(=C([C@@]2(C1CC1Cc3ccc(c(c3C(=O)C1C2O)O)[N+](=O)[O-])O)O)C(=O)N)C
  • InChi: 1S/C21H23N3O9/c1-23(2)14-9-6-8-5-7-3-4-10(24(32)33)15(25)11(7)16(26)12(8)18(28)21(9,31)19(29)13(17(14)27)20(22)30/h3-4,8-9,12,14,18,25,28-29,31H,5-6H2,1-2H3,(H2,22,30)/t8?,9?,12?,14-,18?,21-/m0/s1
  • InChiKey: YYVIYTRBGUDBFA-UMERKKMZSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0217 0.0234 0.021
Loa Loa (eye worm) hypothetical protein 0.0299 0.0458 0.0458
Echinococcus granulosus neurogenic locus notch protein 0.0381 0.0683 0.0683
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0469 0.0925 0.0925
Onchocerca volvulus 0.0703 0.157 0.7268
Echinococcus granulosus tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Leishmania major hypothetical protein, conserved 0.0347 0.059 0.0566
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1306 0.3228 0.3211
Echinococcus granulosus tyrosine protein kinase 0.0331 0.0546 0.0546
Echinococcus multilocularis titin 0.0174 0.0114 0.0114
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0688 0.1529 0.1529
Trichomonas vaginalis CMGC family protein kinase 0.0331 0.0547 0.1647
Brugia malayi Immunoglobulin I-set domain containing protein 0.0228 0.0263 0.0263
Echinococcus multilocularis 0.0207 0.0206 0.0206
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0306 0.0898
Onchocerca volvulus 0.0194 0.0169 0.0729
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.079 0.1808 0.1808
Echinococcus granulosus protein kinase c epsilon type 0.044 0.0845 0.0845
Echinococcus granulosus twitchin 0.0931 0.2196 0.2196
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Brugia malayi Protein kinase domain containing protein 0.0647 0.1415 0.1415
Echinococcus multilocularis rac serine:threonine kinase 0.0354 0.0609 0.0609
Plasmodium vivax glycogen synthase kinase 3, putative 0.0277 0.0399 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Brugia malayi Immunoglobulin domain containing protein 0.0208 0.021 0.021
Entamoeba histolytica PH domain containing protein kinase, putative 0.026 0.0351 0.1601
Entamoeba histolytica protein kinase, putative 0.03 0.046 0.2123
Onchocerca volvulus 0.0174 0.0114 0.0475
Giardia lamblia Kinase, CMGC GSK 0.0277 0.0399 0.087
Leishmania major protein kinase, putative 0.0331 0.0547 0.0523
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0182 0.0136 0.0136
Echinococcus multilocularis myosin iiia 0.0183 0.0138 0.0138
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0241 0.0298 0.0273
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0179 0.0129 0.0104
Entamoeba histolytica casein kinase, putative 0.0234 0.0281 0.1261
Echinococcus multilocularis titin 0.0265 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0193 0.0168 0.0168
Brugia malayi Kinase associated domain 1 family protein 0.0219 0.0239 0.0239
Brugia malayi Cam kinase protein 1 0.0217 0.0234 0.0234
Echinococcus multilocularis twitchin 0.0245 0.0311 0.0311
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0174 0.0116 0.0116
Onchocerca volvulus 0.0141 0.0024 0.0056
Echinococcus granulosus cyclin dependent kinase 19 0.1189 0.2906 0.2906
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0252 0.033 0.033
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Trypanosoma cruzi polo-like protein kinase, putative 0.0582 0.1237 0.1215
Schistosoma mansoni tyrosine kinase 0.0451 0.0876 0.0876
Schistosoma mansoni ste20-related kinase 0.0442 0.0852 0.0852
Trypanosoma brucei trypanothione reductase 0.3769 1 1
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0343 0.0579 0.0556
Echinococcus multilocularis insulin receptor 0.0647 0.1415 0.1415
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0347 0.059 0.2746
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0266 0.0368 0.0368
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0705 0.1576 0.1576
Onchocerca volvulus 0.0381 0.0683 0.3131
Schistosoma mansoni tyrosine kinase 0.0202 0.0193 0.0193
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0688 0.1529 0.1529
Entamoeba histolytica protein kinase 2, putative 0.0338 0.0564 0.2625
Trichomonas vaginalis AGC family protein kinase 0.0369 0.0651 0.1973
Echinococcus granulosus neural cadherin 0.0381 0.0684 0.0684
Loa Loa (eye worm) hypothetical protein 0.0246 0.0313 0.0313
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Brugia malayi Protein kinase domain containing protein 0.0354 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.0233 0.0276 0.0276
Mycobacterium tuberculosis Probable oxidoreductase 0.1306 0.3228 0.2803
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0347 0.059 0.0566
Brugia malayi Immunoglobulin I-set domain containing protein 0.0208 0.021 0.021
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0244 0.0306 0.0282
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0492 0.0991 0.0991
Onchocerca volvulus 0.07 0.1562 0.723
Echinococcus granulosus insulin receptor 0.0647 0.1415 0.1415
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0547 0.0547
Leishmania major protein kinase A catalytic subunit isoform 2 0.0244 0.0306 0.0282
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0208 0.021 0.021
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0181 0.0133 0.0108
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0343 0.0579 0.0556
Echinococcus multilocularis CDC7 cell division cycle 7 0.0194 0.0169 0.0169
Echinococcus multilocularis cyclin 0.0883 0.2064 0.2064
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0268 0.0373 0.0373
Trypanosoma cruzi casein kinase, putative 0.0234 0.0281 0.0256
Brugia malayi Leucine Rich Repeat family protein 0.0174 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.0916 0.0916
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0179 0.0129 0.0104
Echinococcus granulosus dual specificity 0.03 0.046 0.046
Giardia lamblia Kinase, CMGC GSK 0.0277 0.0399 0.087
Brugia malayi RhoGAP domain containing protein 0.0161 0.0079 0.0079
Brugia malayi Serine/threonine-protein kinase SULU 0.0479 0.0953 0.0953
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0217 0.0234 0.0119
Echinococcus multilocularis Immunoglobulin 0.0686 0.1522 0.1522
Schistosoma mansoni cell adhesion molecule 0.0382 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0256 0.034 0.034
Schistosoma mansoni tyrosine kinase 0.0647 0.1415 0.1415
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0381 0.0683 0.0683
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0717 0.1608 0.1608
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0256 0.0341 0.0341
Brugia malayi Protein kinase domain containing protein 0.0417 0.0784 0.0784
Echinococcus multilocularis Glutaredoxin protein 5 0.0266 0.0368 0.0368
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.05 0.1011 0.1011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0217 0.0234 0.0234
Schistosoma mansoni septate junction protein 0.0208 0.021 0.021
Entamoeba histolytica cell division protein kinase 2, putative 0.0272 0.0386 0.1766
Onchocerca volvulus 0.0672 0.1485 0.687
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0159 0.0075 0.0075
Echinococcus multilocularis protein kinase c epsilon type 0.044 0.0845 0.0845
Onchocerca volvulus 0.0193 0.0168 0.0727
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Schistosoma mansoni tyrosine kinase 0.0202 0.0193 0.0193
Entamoeba histolytica protein kinase, putative 0.0254 0.0334 0.1517
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0208 0.021 0.021
Echinococcus granulosus tyrosine kinase 0.0268 0.0373 0.0373
Echinococcus granulosus protein jagged 2 0.0381 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Schistosoma mansoni protein kinase 0.0934 0.2206 0.2206
Schistosoma mansoni tyrosine kinase 0.0621 0.1343 0.1343
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0169 0.01 0.0076
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0244 0.0306 0.0282
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0347 0.059 0.059
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0347 0.059 0.0478
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.01 0.01
Trichomonas vaginalis CK1 family protein kinase 0.0234 0.0281 0.0818
Schistosoma mansoni c4b-binding protein beta chain 0.0703 0.157 0.157
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Trypanosoma cruzi polo-like protein kinase, putative 0.0582 0.1237 0.1215
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0246 0.0313 0.0313
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0256 0.0341 0.0316
Trypanosoma brucei cdc2-related kinase 1 0.0256 0.0341 0.0316
Loa Loa (eye worm) AUR protein kinase 0.0254 0.0334 0.0334
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0382 0.0688 0.0688
Echinococcus granulosus aurora kinase A 0.0254 0.0334 0.0334
Brugia malayi serine/threonine-protein kinase plk-2 0.0582 0.1237 0.1237
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0193 0.0168 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0277 0.0399 0.1187
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0364 0.0364
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0193 0.0168 0.0168
Echinococcus multilocularis protein jagged 1 0.0381 0.0683 0.0683
Leishmania major NADH dehydrogenase, putative 0.0347 0.059 0.0566
Brugia malayi Protein kinase domain containing protein 0.0759 0.1724 0.1724
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0217 0.0234 0.021
Loa Loa (eye worm) hypothetical protein 0.0192 0.0165 0.0165
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0331 0.0547 0.0523
Giardia lamblia Kinase, NEK 0.0293 0.0443 0.1013
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0312 0.0495 0.0495
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Echinococcus granulosus nephrin 0.0193 0.0168 0.0168
Echinococcus granulosus casein kinase I delta 0.0234 0.0281 0.0281
Onchocerca volvulus 0.0703 0.157 0.7268
Schistosoma mansoni serine/threonine protein kinase 0.03 0.046 0.046
Plasmodium vivax unspecified product 0.0216 0.023 0.0114
Echinococcus multilocularis cyclin dependent kinase 0.0256 0.0341 0.0341
Loa Loa (eye worm) AGC/PKN protein kinase 0.0626 0.1358 0.1358
Schistosoma mansoni cell adhesion molecule 0.0193 0.0168 0.0168
Echinococcus granulosus cyclin dependent kinase 9 0.0165 0.009 0.009
Echinococcus multilocularis mitogen activated protein kinase 14 0.0343 0.0579 0.0579
Brugia malayi Casein kinase II, alpha chain 0.0216 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Loa Loa (eye worm) thioredoxin reductase 0.3769 1 1
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0437 0.0837 0.0837
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Giardia lamblia Kinase, CMGC CK2 0.0216 0.023 0.0325
Brugia malayi Immunoglobulin I-set domain containing protein 0.1636 0.4136 0.4136
Echinococcus granulosus casein kinase ii subunit alpha 0.0216 0.023 0.023
Brugia malayi Protein kinase domain containing protein 0.0688 0.1529 0.1529
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0473 0.0938 0.0938
Trypanosoma cruzi casein kinase, putative 0.0234 0.0281 0.0256
Entamoeba histolytica protein kinase domain containing protein 0.0254 0.0334 0.1517
Echinococcus multilocularis neurogenic locus protein delta 0.0381 0.0683 0.0683
Echinococcus multilocularis N chimaerin 0.0161 0.0079 0.0079
Schistosoma mansoni netrin receptor unc5 0.0208 0.021 0.021
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0506 0.1028 0.1028
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1306 0.3228 0.3211
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0161 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0193 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0183 0.0183
Echinococcus granulosus notch 0.0381 0.0683 0.0683
Echinococcus multilocularis protein jagged 1 0.0381 0.0683 0.0683
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0208 0.021 0.021
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0402 0.0742 0.0742
Echinococcus granulosus nervana 2 0.0266 0.0368 0.0368
Brugia malayi Temporarily assigned gene name protein 59 0.0278 0.04 0.04
Trypanosoma cruzi casein kinase, putative 0.0234 0.0281 0.0256
Schistosoma mansoni tyrosine kinase 0.0434 0.0828 0.0828
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0208 0.021 0.021
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0228 0.0263 0.0263
Echinococcus granulosus tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Loa Loa (eye worm) CDC7 protein kinase 0.0194 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0381 0.0684 0.0684
Brugia malayi phosphoinositide-dependent protein kinase I 0.0176 0.012 0.012
Echinococcus granulosus cyclin dependent kinase 1 0.0256 0.0341 0.0341
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0186 0.0146 0.0146
Onchocerca volvulus 0.0703 0.157 0.7268
Brugia malayi Prion-like- 0.0174 0.0114 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0382 0.0688 0.0688
Schistosoma mansoni roundabout 0.0382 0.0688 0.0688
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1306 0.3228 0.3211
Echinococcus multilocularis tyrosine protein kinase Blk 0.0268 0.0373 0.0373
Toxoplasma gondii CMGC kinase, CK2 family 0.0216 0.023 0.0205
Giardia lamblia Kinase, AGC AKT 0.0252 0.033 0.0649
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1306 0.3228 1
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.023 0.1018
Loa Loa (eye worm) TK/ROR protein kinase 0.0244 0.0307 0.0307
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0114 0.0114
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0174 0.0114 0.0114
Entamoeba histolytica protein kinase, putative 0.0347 0.059 0.2749
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0244 0.0306 0.0192
Loa Loa (eye worm) hypothetical protein 0.0307 0.0482 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0306 0.0306
Onchocerca volvulus 0.0381 0.0683 0.3131
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0347 0.059 0.1781
Loa Loa (eye worm) hypothetical protein 0.0782 0.1787 0.1787
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Echinococcus multilocularis peroxidasin 0.0383 0.0689 0.0689
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0186 0.0146 0.0146
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.0826 0.0826
Schistosoma mansoni tyrosine kinase 0.0521 0.1069 0.1069
Brugia malayi Prion-like- 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Echinococcus multilocularis nervana 2 0.0266 0.0368 0.0368
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0254 0.0334 0.0334
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0208 0.021 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Loa Loa (eye worm) AUR protein kinase 0.0254 0.0334 0.0334
Onchocerca volvulus 0.0141 0.0024 0.0056
Echinococcus multilocularis nervana 2 0.0266 0.0368 0.0368
Giardia lamblia Kinase, NEK 0.0293 0.0443 0.1013
Giardia lamblia Kinase, CAMK CAMKL 0.0185 0.0146 0.0053
Trypanosoma brucei polo-like protein kinase 0.0582 0.1237 0.1215
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0182 0.0136 0.0112
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Brugia malayi Thioredoxin reductase 0.3769 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0347 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0141 0.0024 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0471 0.0932 0.0932
Schistosoma mansoni serine/threonine protein kinase 0.044 0.0845 0.0845
Loa Loa (eye worm) hypothetical protein 0.1068 0.2573 0.2573
Echinococcus multilocularis tyrosine protein kinase otk 0.0382 0.0688 0.0688
Onchocerca volvulus 0.0703 0.157 0.7268
Brugia malayi Protein kinase domain containing protein 0.0176 0.012 0.012
Schistosoma mansoni cell adhesion molecule 0.0914 0.2149 0.2149
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0277 0.0399 0.0399
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0331 0.0547 0.0523
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0216 0.023 0.0114
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0343 0.0579 0.0579
Loa Loa (eye worm) AGC/PKA protein kinase 0.0244 0.0306 0.0306
Brugia malayi Protein kinase domain containing protein 0.0303 0.0469 0.0469
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0391 0.0712 0.0712
Echinococcus multilocularis casein kinase i 0.0234 0.0281 0.0281
Giardia lamblia NADH oxidase lateral transfer candidate 0.1306 0.3228 1
Echinococcus granulosus epidermal growth factor receptor 0.0747 0.1691 0.1691
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0329 0.0542 0.0542
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0347 0.059 0.0566
Echinococcus multilocularis tyrosine kinase 0.0141 0.0024 0.0024
Giardia lamblia Kinase, CMGC MAPK 0.0181 0.0133 0.0012
Schistosoma mansoni cell adhesion molecule 0.0208 0.021 0.021
Schistosoma mansoni nephrin 0.0879 0.2054 0.2054
Echinococcus multilocularis c4b binding protein beta chain 0.0703 0.157 0.157
Schistosoma mansoni tyrosine kinase 0.0302 0.0468 0.0468
Echinococcus multilocularis casein kinase I alpha 0.0234 0.0281 0.0281
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Brugia malayi Immunoglobulin domain containing protein 0.0208 0.021 0.021
Schistosoma mansoni tyrosine kinase 0.0452 0.088 0.088
Brugia malayi Protein kinase domain containing protein 0.0347 0.059 0.059
Brugia malayi Protein kinase domain containing protein 0.0627 0.1361 0.1361
Plasmodium vivax serine/threonine kinase-1, putative 0.0331 0.0547 0.0435
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0759 0.1724 0.1724
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0193 0.0168 0.0168
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0183 0.0138 0.0578
Brugia malayi serine/threonine kinase 12 0.0254 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Entamoeba histolytica protein kinase, putative 0.0179 0.0129 0.0534
Schistosoma mansoni serine/threonine protein kinase 0.0849 0.1971 0.1971
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0183 0.0138 0.0114
Echinococcus granulosus tyrosine protein kinase otk 0.0382 0.0688 0.0688
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0266 0.0368 0.0368
Echinococcus multilocularis protein kinase c iota type 0.0615 0.1329 0.1329
Echinococcus multilocularis titin 0.0174 0.0114 0.0114
Trypanosoma brucei hypothetical protein, conserved 0.0347 0.059 0.0566
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0347 0.059 0.059
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1306 0.3228 0.3211
Trichomonas vaginalis STE family protein kinase 0.0186 0.0146 0.04
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0467 0.0922 0.0922
Echinococcus granulosus Immunoglobulin 0.0686 0.1522 0.1522
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.157 0.3954 0.3954
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1028 0.1028
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0347 0.059 0.059
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0347 0.059 0.0566
Giardia lamblia High cysteine protein 0.0381 0.0683 0.1789
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Brugia malayi Protein kinase domain containing protein 0.0415 0.0779 0.0779
Echinococcus granulosus cGMP dependent protein kinase 1 0.0182 0.0136 0.0136
Echinococcus granulosus Glutaredoxin protein 5 0.0266 0.0368 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.0953 0.0953
Giardia lamblia Kinase, STE STE20 0.0183 0.0138 0.003
Echinococcus multilocularis casein kinase I alpha 0.0234 0.0281 0.0281
Schistosoma mansoni atypical protein kinase C 0.0628 0.1365 0.1365
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0241 0.0298 0.0298
Echinococcus granulosus serine:threonine protein kinase N2 0.0626 0.1358 0.1358
Brugia malayi Cadherin domain containing protein 0.0381 0.0684 0.0684
Brugia malayi Protein kinase domain containing protein 0.0966 0.2292 0.2292
Plasmodium falciparum calcium-dependent protein kinase 3 0.0217 0.0234 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0436 0.0436
Schistosoma mansoni protein kinase 0.0476 0.0945 0.0945
Entamoeba histolytica protein kinase, putative 0.0629 0.1367 0.6482
Entamoeba histolytica protein kinase, putative 0.0629 0.1367 0.6482
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0186 0.0146 0.0146
Schistosoma mansoni titin 0.0174 0.0114 0.0114
Trypanosoma cruzi casein kinase, putative 0.0234 0.0281 0.0256
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0208 0.021 0.021
Echinococcus granulosus nervana 2 0.0266 0.0368 0.0368
Echinococcus multilocularis roundabout 2 0.0402 0.0742 0.0742
Schistosoma mansoni tyrosine kinase 0.0647 0.1415 0.1415
Toxoplasma gondii histone kinase SNF1, putative 0.0169 0.01 0.0076
Echinococcus multilocularis fat cadherin tumor suppressor 0.0381 0.0684 0.0684
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1306 0.3228 0.3211
Schistosoma mansoni serine/threonine protein kinase 0.0759 0.1724 0.1724
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0183 0.0138 0.0114
Trichomonas vaginalis CK1 family protein kinase 0.0234 0.0281 0.0818
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1306 0.3228 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0465 0.0916 0.0916
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.03 0.046 0.0436
Brugia malayi MAP kinase sur-1 0.0181 0.0133 0.0133
Brugia malayi Protein kinase domain containing protein 0.0194 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0299 0.0458 0.0458
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0169 0.01 0.0076
Entamoeba histolytica protein kinase , putative 0.0254 0.0334 0.1517
Echinococcus granulosus peroxidasin 0.0383 0.0689 0.0689
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.0234 0.0673
Brugia malayi Fes/CIP4 homology domain containing protein 0.022 0.0242 0.0242
Brugia malayi Immunoglobulin I-set domain containing protein 0.0705 0.1576 0.1576
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Echinococcus granulosus titin 0.0174 0.0114 0.0114
Plasmodium falciparum protein kinase 5 0.0256 0.0341 0.0316
Schistosoma mansoni serine/threonine protein kinase 0.0582 0.1237 0.1237
Echinococcus granulosus thioredoxin glutathione reductase 0.3769 1 1
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0703 0.157 0.157
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Echinococcus multilocularis 0.026 0.0351 0.0351
Giardia lamblia Kinase, CDC7 0.0194 0.0169 0.0127
Brugia malayi Protein kinase domain containing protein 0.0134 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Echinococcus multilocularis Immunoglobulin 0.0208 0.021 0.021
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0208 0.021 0.021
Onchocerca volvulus 0.0141 0.0024 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Schistosoma mansoni sulfide quinone reductase 0.0347 0.059 0.059
Echinococcus multilocularis protein kinase shaggy 0.0277 0.0399 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0281 0.0281
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0176 0.012 0.012
Brugia malayi cell division control protein 2 homolog 0.0256 0.0341 0.0341
Entamoeba histolytica protein kinase, putative 0.0277 0.0399 0.183
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0248 0.0319 0.0319
Schistosoma mansoni tyrosine kinase 0.0747 0.1691 0.1691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Echinococcus multilocularis casein kinase I delta 0.0234 0.0281 0.0281
Leishmania major protein kinase, putative 0.0331 0.0547 0.0523
Giardia lamblia Kinase, AGC PKA 0.0244 0.0306 0.0572
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0186 0.0146 0.0146
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0179 0.0129 0.0104
Brugia malayi Immunoglobulin I-set domain containing protein 0.0208 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0208 0.021 0.021
Leishmania major protein kinase A catalytic subunit isoform 1 0.0244 0.0306 0.0282
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0582 0.1237 0.1237
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0343 0.0579 0.0556
Schistosoma mansoni protein kinase 0.0216 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0499 0.1009 0.1009
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.1088 0.1088
Echinococcus multilocularis serine:threonine protein kinase 0.0246 0.0313 0.0313
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0179 0.0129 0.0129
Echinococcus multilocularis mitogen activated protein kinase 11 0.0343 0.0579 0.0579
Loa Loa (eye worm) hypothetical protein 0.0686 0.1522 0.1522
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0208 0.021 0.021
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0176 0.012 0.012
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0241 0.0298 0.0273
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0521 0.1069 0.1069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0114 0.0114
Plasmodium falciparum calcium-dependent protein kinase 2 0.0217 0.0234 0.021
Trypanosoma brucei cdc2-related kinase 3 0.0256 0.0341 0.0316
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0256 0.0341 0.0341
Schistosoma mansoni peroxidasin 0.0209 0.0211 0.0211
Onchocerca volvulus 0.0703 0.157 0.7268
Giardia lamblia Thioredoxin reductase 0.0347 0.059 0.1486
Plasmodium falciparum serine/threonine protein kinase 0.0179 0.0129 0.0104
Trypanosoma cruzi NADH dehydrogenase, putative 0.0347 0.059 0.0566
Trichomonas vaginalis CMGC family protein kinase 0.0256 0.0341 0.1005
Echinococcus granulosus casein kinase I gamma 0.0459 0.0899 0.0899
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0469 0.0925 0.0925
Trichomonas vaginalis AGC family protein kinase 0.0385 0.0696 0.2113
Trichomonas vaginalis CAMK family protein kinase 0.0272 0.0385 0.1144
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0241 0.0298 0.0298
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0263 0.0361 0.0337
Brugia malayi casein kinase I 0.0234 0.0281 0.0281
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0528 0.1088 0.1088
Loa Loa (eye worm) gastrulation defective protein 1 0.1118 0.271 0.271
Trichomonas vaginalis AGC family protein kinase 0.0363 0.0635 0.1923
Loa Loa (eye worm) AGC/AKT protein kinase 0.0629 0.1367 0.1367
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0277 0.0399 0.0375
Toxoplasma gondii casein kinase I 0.0234 0.0281 0.0256
Echinococcus granulosus delta-like protein 1 0.0381 0.0683 0.0683
Brugia malayi Delta serrate ligand family protein 0.0381 0.0683 0.0683
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Brugia malayi hypothetical protein 0.0241 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Entamoeba histolytica protein kinase, putative 0.0217 0.0234 0.1039
Brugia malayi hypothetical protein 0.0705 0.1576 0.1576
Echinococcus multilocularis cyclin dependent kinase 19 0.1189 0.2906 0.2906
Loa Loa (eye worm) disorganized muscle protein 1 0.0174 0.0114 0.0114
Onchocerca volvulus 0.0265 0.0364 0.1642
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0347 0.059 0.2746
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0169 0.0469
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Plasmodium falciparum thioredoxin reductase 0.3769 1 1
Schistosoma mansoni neuroglian 0.0402 0.0742 0.0742
Loa Loa (eye worm) one IG domain family member 0.0174 0.0114 0.0114
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0402 0.0742 0.0742
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0269 0.0375 0.0351
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0479 0.0953 0.0953
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0338 0.0564 0.0453
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0347 0.059 0.059
Onchocerca volvulus 0.0138 0.0015 0.0013
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0274 0.0389 0.0389
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0181 0.0133 0.0108
Echinococcus granulosus titin 0.0174 0.0114 0.0114
Trypanosoma cruzi NADH dehydrogenase, putative 0.0347 0.059 0.0566
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0114 0.0114
Plasmodium vivax protein kinase Crk2 0.0256 0.0341 0.0226
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0217 0.0234 0.021
Onchocerca volvulus Putative titin 0.0174 0.0114 0.0475
Echinococcus granulosus protein jagged 2 0.0381 0.0683 0.0683
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0849 0.1971 0.1971
Schistosoma mansoni basigin related 0.0208 0.021 0.021
Echinococcus multilocularis transfer RNA-Phe 0.0193 0.0168 0.0168
Brugia malayi protein-tyrosine kinase 0.0268 0.0373 0.0373
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0959 0.2274 0.2274
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0228 0.0263 0.0263
Echinococcus multilocularis casein kinase ii subunit alpha 0.0216 0.023 0.023
Onchocerca volvulus 0.0629 0.1366 0.6315
Echinococcus granulosus serine threonine protein kinase nrc 0.0338 0.0564 0.0564
Loa Loa (eye worm) TK/EPH protein kinase 0.0246 0.0312 0.0312
Brugia malayi ephrin receptor 1 precursor 0.0135 0.0008 0.0008
Brugia malayi map kinase activated protein kinase protein 2 0.0849 0.1971 0.1971
Echinococcus granulosus cyclin 0.0883 0.2064 0.2064
Echinococcus multilocularis neurogenic locus protein delta 0.0381 0.0683 0.0683
Entamoeba histolytica protein kinase domain containing protein 0.0141 0.0025 0.0033
Brugia malayi GCC2 and GCC3 family protein 0.1084 0.2617 0.2617
Echinococcus granulosus tyrosine protein kinase ABL1 0.0141 0.0024 0.0024
Brugia malayi EGF-like domain containing protein 0.0429 0.0815 0.0815
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0465 0.0916 0.0916
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0217 0.0234 0.0234
Brugia malayi glutamate synthase 0.0347 0.059 0.059
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0347 0.059 0.0566
Brugia malayi Protein kinase domain 0.0186 0.0146 0.0146
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0329 0.0542 0.0542
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0465 0.0916 0.0916
Loa Loa (eye worm) TK/FAK protein kinase 0.0627 0.1361 0.1361
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0234 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Echinococcus granulosus glutamate synthase 0.0347 0.059 0.059
Echinococcus granulosus mitogen activated protein kinase 14 0.0343 0.0579 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0272 0.0385 0.1144
Entamoeba histolytica protein kinase, putative 0.022 0.0242 0.1074
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Trichomonas vaginalis STE family protein kinase 0.0183 0.0138 0.0375
Trichomonas vaginalis AGC family protein kinase 0.0176 0.012 0.0316
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0399 0.183
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Brugia malayi Prion-like- 0.0174 0.0114 0.0114
Trichomonas vaginalis apoptosis inducing factor, putative 0.0347 0.059 0.1781
Echinococcus granulosus serine:threonine protein kinase 0.0246 0.0313 0.0313
Leishmania major protein kinase, putative 0.0254 0.0334 0.0309
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0347 0.059 0.0566
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Echinococcus granulosus casein kinase I delta 0.0234 0.0281 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0759 0.1724 0.1724
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0311 0.0311
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.079 0.1808 0.1808
Trichomonas vaginalis glutamate synthase, putative 0.0347 0.059 0.1781
Brugia malayi Protein kinase domain containing protein 0.0629 0.1367 0.1367
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0244 0.0306 0.0282
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1306 0.3228 0.3211
Loa Loa (eye worm) Notch2 0.0381 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Entamoeba histolytica protein kinase, putative 0.0613 0.1322 0.6267
Loa Loa (eye worm) TK protein kinase 0.0197 0.0178 0.0178
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0169 0.01 0.01
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0525 0.108 0.108
Entamoeba histolytica protein kinase, putative 0.0142 0.0028 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.0361 0.1647
Schistosoma mansoni slit 0.0381 0.0685 0.0685
Entamoeba histolytica serine/threonine protein kinase, putative 0.0582 0.1237 0.5857
Echinococcus multilocularis tyrosine protein kinase Src42A 0.02 0.0187 0.0187
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0569 0.1202 0.1202
Loa Loa (eye worm) hypothetical protein 0.0686 0.1523 0.1523
Echinococcus multilocularis C type lectin domian containing protein 0.0703 0.157 0.157
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1306 0.3228 0.3211
Loa Loa (eye worm) TK/ABL protein kinase 0.0141 0.0024 0.0024
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1306 0.3228 0.3228
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0181 0.0133 0.0108
Echinococcus multilocularis casein kinase I alpha 0.0234 0.0281 0.0281
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0347 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0532 0.1099 0.1099
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Loa Loa (eye worm) TK protein kinase 0.04 0.0736 0.0736
Echinococcus multilocularis dual specificity 0.03 0.046 0.046
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0667 0.1469 0.1469
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1306 0.3228 1
Echinococcus granulosus low density lipoprotein receptor ldl 0.0208 0.021 0.021
Onchocerca volvulus 0.0703 0.157 0.7268
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Schistosoma mansoni protein kinase 0.0571 0.1205 0.1205
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0181 0.0133 0.0108
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0959 0.2274 0.2274
Brugia malayi Variant SH3 domain containing protein 0.0161 0.0079 0.0079
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0114 0.0114
Schistosoma mansoni disulfide oxidoreductase 0.0347 0.059 0.059
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0161 0.0079 0.0079
Loa Loa (eye worm) animal heme peroxidase 0.0174 0.0114 0.0114
Trichomonas vaginalis glutathione reductase, putative 0.1306 0.3228 1
Entamoeba histolytica casein kinase 1, putative 0.0234 0.0281 0.1261
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0686 0.1522 0.1522
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0966 0.2292 0.2292
Loa Loa (eye worm) hypothetical protein 0.0397 0.0729 0.0729
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0402 0.0742 0.0742
Entamoeba histolytica thioredoxin reductase, putative 0.0347 0.059 0.2746
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Echinococcus granulosus roundabout 2 0.1088 0.2627 0.2627
Echinococcus granulosus growth factor receptor bound protein 2 0.0134 0.0006 0.0006
Brugia malayi serine/threonine protein kinase 6 0.0254 0.0334 0.0334
Onchocerca volvulus Peroxidasin homolog 0.0174 0.0114 0.0475
Echinococcus multilocularis protein tyrosine kinase 0.0621 0.1343 0.1343
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0234 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.01 0.01
Schistosoma mansoni vesicular amine transporter 0.0686 0.1522 0.1522
Echinococcus granulosus insulin growth factor binding 0.0174 0.0114 0.0114
Echinococcus multilocularis neurogenic locus notch protein 4 0.0381 0.0683 0.0683
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0347 0.059 0.2746
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0347 0.059 0.0566
Loa Loa (eye worm) hypothetical protein 0.0705 0.1576 0.1576
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0402 0.0742 0.0742
Onchocerca volvulus 0.0307 0.0482 0.219
Brugia malayi Fibronectin type III domain containing protein 0.0705 0.1576 0.1576
Brugia malayi Immunoglobulin I-set domain containing protein 0.0402 0.0742 0.0742
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0338 0.0564 0.0541
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0263 0.0361 0.0361
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0894 0.2095 0.2095
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0361 0.0361
Schistosoma mansoni glutamate synthase 0.0347 0.059 0.059
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0244 0.0306 0.0306
Trypanosoma cruzi aurora B kinase, putative 0.0254 0.0334 0.0309
Brugia malayi Tyrosine-protein kinase abl-1 0.0202 0.0193 0.0193
Schistosoma mansoni serine/threonine protein kinase 0.1189 0.2906 0.2906
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0298 0.0455 0.1362
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0437 0.0837 0.0837
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1306 0.3228 0.3228
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Echinococcus granulosus NDR protein kinase 0.0347 0.059 0.059
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0244 0.0307 0.0307
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Schistosoma mansoni tyrosine kinase 0.0521 0.1069 0.1069
Loa Loa (eye worm) hypothetical protein 0.0688 0.1529 0.1529
Onchocerca volvulus 0.0414 0.0774 0.3554
Echinococcus granulosus raf serine:threonine protein kinase 0.016 0.0077 0.0077
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Echinococcus granulosus calcium dependent protein kinase 0.0146 0.0038 0.0038
Schistosoma mansoni titin 0.0265 0.0364 0.0364
Echinococcus granulosus tyrosine kinase 0.0141 0.0024 0.0024
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0347 0.059 0.059
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0244 0.0306 0.0282
Plasmodium falciparum calcium-dependent protein kinase 5 0.0217 0.0234 0.021
Plasmodium falciparum thioredoxin reductase 0.1306 0.3228 0.3211
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0432 0.0825 0.0825
Echinococcus granulosus cGMP dependent protein kinase 0.0182 0.0136 0.0136
Echinococcus multilocularis hemicentin 1 0.0382 0.0688 0.0688
Schistosoma mansoni protein kinase 0.0934 0.2206 0.2206
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0528 0.1088 0.1088
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0277 0.0399 0.0375
Schistosoma mansoni serine/threonine kinase 0.0347 0.059 0.059
Echinococcus granulosus protein kinase c iota type 0.0615 0.1329 0.1329
Loa Loa (eye worm) TK/INSR protein kinase 0.0647 0.1415 0.1415
Echinococcus granulosus dual specificity 0.0263 0.0361 0.0361
Schistosoma mansoni septate junction protein 0.0382 0.0688 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.009 0.009
Trichomonas vaginalis AGC family protein kinase 0.0176 0.012 0.0316
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0382 0.0688 0.0688
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus granulosus activin receptor type 0.0141 0.0025 0.0025
Schistosoma mansoni protein kinase 0.0139 0.0018 0.0018
Echinococcus granulosus dual specificity 0.03 0.046 0.046
Schistosoma mansoni kinase 0.0165 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0389 0.0705 0.0705
Brugia malayi Immunoglobulin domain containing protein 0.0208 0.021 0.021
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0142 0.0028 0.0047
Plasmodium falciparum serine/threonine protein kinase KIN 0.0169 0.01 0.0076
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0183 0.0138 0.0578
Trypanosoma brucei Casein kinase II 0.0216 0.023 0.0205
Brugia malayi Protein kinase domain containing protein 0.0327 0.0537 0.0537
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0174 0.0114 0.0114
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0613 0.1322 0.1322
Brugia malayi p70 ribosomal S6 kinase beta 0.0613 0.1322 0.1322
Brugia malayi protein unc-22 0.0265 0.0364 0.0364
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0354 0.0609 0.0609
Onchocerca volvulus 0.0397 0.0729 0.3345
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0334 0.0983
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Echinococcus granulosus epidermal growth factor receptor 0.0521 0.1069 0.1069
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0169 0.01 0.0076
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0312 0.0494 0.0494
Echinococcus granulosus tyrosine protein kinase Src64B 0.0329 0.0542 0.0542
Giardia lamblia Glutamate synthase 0.0347 0.059 0.1486
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0331 0.0547 0.0523
Echinococcus granulosus mitogen activated protein kinase 11 0.0343 0.0579 0.0579
Echinococcus multilocularis serine:threonine protein kinase N2 0.0279 0.0404 0.0404
Schistosoma mansoni laminin gamma-3 chain 0.0381 0.0683 0.0683
Giardia lamblia Kinase, CMGC CDK 0.0256 0.0341 0.0682
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0181 0.0133 0.0108
Echinococcus granulosus down syndrome cell adhesion 0.0174 0.0114 0.0114
Onchocerca volvulus Serine\/threonine kinase homolog 0.0354 0.0609 0.2782
Onchocerca volvulus Slit protein homolog 0.0429 0.0815 0.3745
Plasmodium falciparum calcium-dependent protein kinase 1 0.0217 0.0234 0.021
Toxoplasma gondii AGC kinase 0.0244 0.0306 0.0282
Echinococcus multilocularis activin receptor type 0.0141 0.0025 0.0025
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0274 0.0389 0.0389
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0402 0.0742 0.0742
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0241 0.0298 0.0298
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0331 0.0547 0.0547
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0263 0.0361 0.0337
Loa Loa (eye worm) hypothetical protein 0.0993 0.2367 0.2367
Schistosoma mansoni protein kinase 0.0934 0.2206 0.2206
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0343 0.0579 0.0556
Plasmodium vivax thioredoxin reductase, putative 0.3769 1 1
Echinococcus granulosus serine/threonine protein kinase 0.0354 0.0609 0.0609
Entamoeba histolytica PH domain containing protein kinase, putative 0.0354 0.0609 0.2841
Onchocerca volvulus 0.0347 0.059 0.2693
Onchocerca volvulus 0.0234 0.0281 0.125
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0161 0.0079 0.0079
Echinococcus granulosus Immunoglobulin 0.0208 0.021 0.021
Schistosoma mansoni tyrosine kinase 0.0451 0.0876 0.0876
Plasmodium falciparum casein kinase 1 0.0234 0.0281 0.0256
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0849 0.1971 0.1971
Echinococcus multilocularis tyrosine protein kinase 0.0331 0.0546 0.0546
Entamoeba histolytica hypothetical protein 0.0263 0.0361 0.1647
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0133 0.0358
Trichomonas vaginalis STE family protein kinase 0.0186 0.0146 0.04
Loa Loa (eye worm) hypothetical protein 0.0208 0.021 0.021
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0277 0.0399 0.0399
Echinococcus multilocularis mitogen activated protein kinase 3 0.0181 0.0133 0.0133
Echinococcus multilocularis glutamate synthase 0.0347 0.059 0.059
Echinococcus multilocularis neuroglian 0.0402 0.0742 0.0742
Brugia malayi C1-like domain containing protein 0.0469 0.0925 0.0925
Brugia malayi Immunoglobulin I-set domain containing protein 0.0402 0.0742 0.0742
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1306 0.3228 0.3211
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0254 0.0334 0.1517
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0759 0.1724 0.1724
Schistosoma mansoni serine/threonine protein kinase 0.0525 0.108 0.108
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0347 0.059 0.1486
Echinococcus granulosus contactin 0.0402 0.0742 0.0742
Leishmania major hypothetical protein, conserved 0.0347 0.059 0.0566
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0369 0.0651 0.0651
Brugia malayi basement membrane proteoglycan 0.0208 0.021 0.021
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0354 0.0609 0.0609
Echinococcus multilocularis dual specificity 0.03 0.046 0.046
Loa Loa (eye worm) hypothetical protein 0.0217 0.0234 0.0234
Schistosoma mansoni tyrosine kinase 0.0451 0.0876 0.0876
Schistosoma mansoni titin 0.0174 0.0114 0.0114
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0334 0.0983
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0183 0.0138 0.0114
Echinococcus multilocularis raf serine:threonine protein kinase 0.016 0.0077 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.059 0.0566
Echinococcus multilocularis expressed conserved protein 0.0182 0.0136 0.0136
Trichomonas vaginalis AGC family protein kinase 0.0369 0.0651 0.1973
Brugia malayi Muscle positioning protein 4 0.0381 0.0683 0.0683
Loa Loa (eye worm) AGC/PKA protein kinase 0.0244 0.0306 0.0306
Schistosoma mansoni protein kinase 0.0476 0.0945 0.0945
Echinococcus granulosus tyrosine protein kinase Lyn 0.0401 0.0738 0.0738
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Plasmodium falciparum cGMP-dependent protein kinase 0.0182 0.0136 0.0112
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1064 0.2563 0.2563
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0186 0.0146 0.0146
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0347 0.059 0.0566
Leishmania major protein kinase, putative 0.0217 0.0234 0.021
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0347 0.059 0.1781
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0274 0.0389 0.0389
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1306 0.3228 0.3228
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0329 0.0542 0.0542
Brugia malayi Egg laying defective protein 4 0.0182 0.0136 0.0136
Echinococcus granulosus serine:threonine kinase SAD 1 0.0169 0.01 0.01
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1306 0.3228 1
Schistosoma mansoni serine/threonine protein kinase 0.0274 0.0389 0.0389
Loa Loa (eye worm) hypothetical protein 0.0208 0.021 0.021
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Echinococcus multilocularis neural cadherin 0.0381 0.0684 0.0684
Brugia malayi Hr1 repeat family protein 0.0626 0.1358 0.1358
Brugia malayi Prion-like- 0.0382 0.0688 0.0688
Echinococcus multilocularis tyrosine protein kinase shark 0.0373 0.0663 0.0663
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0437 0.0837 0.0837
Giardia lamblia Kinase, STE STE20 0.0186 0.0146 0.0056
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0401 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Entamoeba histolytica disulphide oxidoreductase, putative 0.0347 0.059 0.2746
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Brugia malayi Calcium binding EGF domain containing protein 0.0381 0.0683 0.0683
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Schistosoma mansoni kinase 0.0622 0.1346 0.1346
Brugia malayi Immunoglobulin I-set domain containing protein 0.0265 0.0364 0.0364
Brugia malayi serine/threonine-protein kinase PAK 7 0.05 0.1011 0.1011
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0268 0.0373 0.0373
Echinococcus multilocularis serine:threonine protein kinase 3 0.0553 0.1158 0.1158
Loa Loa (eye worm) hypothetical protein 0.0705 0.1576 0.1576
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0347 0.059 0.059
Brugia malayi notch-like transmembrane receptor 0.0381 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0246 0.0313 0.0918
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0402 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Schistosoma mansoni septate junction protein 0.0208 0.021 0.021
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0347 0.059 0.059
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0338 0.0564 0.0564
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.01 0.01
Brugia malayi serine/threonine-protein kinase 6 0.0254 0.0334 0.0334
Schistosoma mansoni nephrin related 0.0208 0.021 0.021
Brugia malayi Peroxidasin 0.0383 0.0689 0.0689
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0181 0.0133 0.0108
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0208 0.021 0.021
Echinococcus multilocularis hypothetical protein 0.0219 0.0239 0.0239
Brugia malayi Protein kinase domain containing protein 0.0141 0.0024 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Trypanosoma cruzi trypanothione reductase, putative 0.3769 1 1
Entamoeba histolytica protein kinase, putative 0.0263 0.0361 0.1647
Schistosoma mansoni titin 0.0174 0.0114 0.0114
Onchocerca volvulus 0.0703 0.157 0.7268
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1028 0.1028
Echinococcus granulosus tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Echinococcus granulosus ephrin type A receptor 4 A 0.0208 0.0208 0.0208
Trichomonas vaginalis CMGC family protein kinase 0.0277 0.0399 0.1187
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0319 0.0936
Echinococcus granulosus serine:threonine protein kinase N2 0.0279 0.0404 0.0404
Echinococcus granulosus Vam6:Vps39 protein 0.0241 0.0298 0.0298
Loa Loa (eye worm) glutathione reductase 0.3769 1 1
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0553 0.1158 0.1158
Echinococcus multilocularis Immunoglobulin 0.0208 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0894 0.2095 0.2095
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Brugia malayi protein kinase C II. 0.044 0.0845 0.0845
Onchocerca volvulus 0.0141 0.0024 0.0056
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0479 0.0953 0.0953
Echinococcus granulosus c src tyrosine kinase 0.0202 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0306 0.0306
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0175 0.0117 0.0092
Loa Loa (eye worm) hypothetical protein 0.0193 0.0168 0.0168
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0277 0.0399 0.0399
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0192 0.0165 0.0165
Echinococcus multilocularis neurogenic locus notch protein 0.0381 0.0683 0.0683
Schistosoma mansoni tyrosine kinase 0.0329 0.0542 0.0542
Loa Loa (eye worm) cyclin domain-containing protein 0.0883 0.2064 0.2064
Echinococcus granulosus CDC7 cell division cycle 7 0.0194 0.0169 0.0169
Brugia malayi basement membrane proteoglycan precursor 0.0208 0.021 0.021
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0161 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0646 0.1412 0.1412
Toxoplasma gondii thioredoxin reductase 0.3769 1 1
Trypanosoma cruzi casein kinase II, putative 0.0216 0.023 0.0205
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0265 0.0364 0.0364
Echinococcus granulosus casein kinase I alpha 0.0234 0.0281 0.0281
Plasmodium vivax serine/threonine protein kinase, putative 0.0179 0.0129 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus granulosus mitogen activated protein kinase 0.0181 0.0133 0.0133
Loa Loa (eye worm) projectin 0.0193 0.0168 0.0168
Schistosoma mansoni protein kinase 0.0186 0.0146 0.0146
Trypanosoma brucei aurora B kinase 0.0254 0.0334 0.0309
Brugia malayi Protein kinase domain containing protein 0.0141 0.0024 0.0024
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0217 0.0234 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Echinococcus multilocularis cyclin dependent kinase 9 0.0165 0.009 0.009
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0476 0.0945 0.0945
Plasmodium falciparum serine/threonine protein kinase, putative 0.0254 0.0334 0.0309
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0347 0.059 0.059
Echinococcus granulosus c4b binding protein beta chain 0.0703 0.157 0.157
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Schistosoma mansoni protein kinase 0.0254 0.0334 0.0334
Echinococcus multilocularis thioredoxin glutathione reductase 0.3769 1 1
Echinococcus granulosus protein jagged 1 0.0381 0.0683 0.0683
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0217 0.0234 0.0234
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0244 0.0307 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0626 0.1358 0.1358
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0686 0.1522 0.1522
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Echinococcus granulosus roundabout 2 0.0402 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.1084 0.2617 0.2617
Loa Loa (eye worm) LAD-2 short isoform 0.0208 0.021 0.021
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0347 0.059 0.0566
Leishmania major trypanothione reductase 0.3769 1 1
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0261 0.0354 0.0354
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0208 0.021 0.021
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0244 0.0306 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0381 0.0684 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0341 0.0341
Entamoeba histolytica p21-activated kinase 0.0202 0.0191 0.0832
Loa Loa (eye worm) TK protein kinase 0.0565 0.119 0.119
Toxoplasma gondii aurora kinase 0.0254 0.0334 0.0309
Schistosoma mansoni basigin related 0.0208 0.021 0.021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0136 0.0136
Schistosoma mansoni ephrin receptor 0.0208 0.0208 0.0208
Brugia malayi Protein kinase domain containing protein 0.0688 0.1529 0.1529
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Schistosoma mansoni protein kinase 0.0415 0.0779 0.0779
Entamoeba histolytica hypothetical protein 0.0413 0.0773 0.3628
Schistosoma mansoni tyrosine kinase 0.0391 0.0712 0.0712
Schistosoma mansoni notch 0.0381 0.0683 0.0683
Schistosoma mansoni hypothetical protein 0.0219 0.0239 0.0239
Entamoeba histolytica protein kinase, putative 0.0155 0.0063 0.0216
Echinococcus multilocularis dual specificity 0.0263 0.0361 0.0361
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Echinococcus multilocularis fibropellin Ia 0.0381 0.0683 0.0683
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0347 0.059 0.059
Onchocerca volvulus Netrin receptor homolog 0.0236 0.0286 0.1274
Brugia malayi Protein kinase domain containing protein 0.0141 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.07 0.1562 0.1562
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0329 0.0542 0.0542
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0254 0.0334 0.1517
Brugia malayi Protein kinase domain containing protein 0.0331 0.0547 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0443 0.1324
Loa Loa (eye worm) TK/ALK protein kinase 0.0327 0.0536 0.0536
Brugia malayi Stress-activated protein kinase jnk-1 0.0569 0.1202 0.1202
Brugia malayi Immunoglobulin I-set domain containing protein 0.0565 0.119 0.119
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0347 0.059 0.0566
Loa Loa (eye worm) thyroid receptor interactor 0.022 0.0242 0.0242
Trichomonas vaginalis glutamate synthase, putative 0.0347 0.059 0.1781
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0329 0.0542 0.0542
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.059 0.0566
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Brugia malayi Animal haem peroxidase family protein 0.0174 0.0114 0.0114
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0165 0.009 0.009
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0077 0.0077
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0176 0.012 0.012
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0241 0.0298 0.0273
Schistosoma mansoni serine/threonine protein kinase 0.0569 0.1202 0.1202
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1306 0.3228 0.2803
Brugia malayi intracellular kinase 0.0277 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0299 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Echinococcus granulosus neurogenic locus notch protein 4 0.0381 0.0683 0.0683
Toxoplasma gondii AGC kinase 0.0613 0.1322 0.13
Echinococcus multilocularis neurogenic locus notch protein 0.0381 0.0683 0.0683
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0347 0.059 0.1781
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1306 0.3228 1
Plasmodium falciparum glutathione reductase 0.1306 0.3228 0.3211
Brugia malayi Cyclin C 0.1765 0.4491 0.4491
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0169 0.0469
Echinococcus granulosus rho-associated protein kinase 1 0.07 0.1562 0.1562
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Plasmodium falciparum calcium-dependent protein kinase 4 0.0217 0.0234 0.021
Loa Loa (eye worm) CAMK protein kinase 0.0265 0.0364 0.0364
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0402 0.0742 0.0742
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0382 0.0688 0.3151
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0193 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0175 0.0119 0.0119
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0347 0.059 0.0566
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0506 0.1028 0.1028
Echinococcus multilocularis mitogen activated protein kinase 14 0.0343 0.0579 0.0579
Brugia malayi Protein kinase domain containing protein 0.0331 0.0546 0.0546
Brugia malayi SH2 domain containing protein 0.0471 0.0932 0.0932
Onchocerca volvulus 0.0703 0.157 0.7268
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0234 0.0281 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0169 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0141 0.0024 0.0024
Echinococcus multilocularis death associated protein kinase 1 0.0958 0.2272 0.2272
Loa Loa (eye worm) SRC-1 0.0329 0.0542 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0133 0.0358
Brugia malayi Protein kinase domain containing protein 0.0246 0.0313 0.0313
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0347 0.059 0.2746
Echinococcus granulosus Protein kinase C brain isozyme 0.0525 0.108 0.108
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0347 0.059 0.2746
Toxoplasma gondii rhoptry neck protein RON9 0.0703 0.157 0.1549
Schistosoma mansoni cell polarity protein 0.0381 0.0683 0.0683
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0379 0.0678 0.0678
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0465 0.0916 0.0916
Loa Loa (eye worm) hypothetical protein 0.0244 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0141 0.0024 0.0024
Brugia malayi Doublecortin family protein 0.0325 0.053 0.053
Echinococcus granulosus titin 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0383 0.0689 0.0689
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0347 0.059 0.059
Echinococcus multilocularis calcium dependent protein kinase 0.0146 0.0038 0.0038
Brugia malayi Calcium binding EGF domain containing protein 0.0381 0.0683 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0192 0.0165 0.0457
Echinococcus multilocularis serine:threonine protein kinase N2 0.0626 0.1358 0.1358
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0354 0.0609 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0234 0.0234
Echinococcus granulosus neuroglian 0.0402 0.0742 0.0742
Loa Loa (eye worm) AGC/PKG protein kinase 0.0182 0.0136 0.0136
Schistosoma mansoni slit 0.0174 0.0116 0.0116
Echinococcus granulosus neurogenic locus notch protein 0.0381 0.0683 0.0683
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0433 0.0826 0.0826
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0181 0.0133 0.0133
Brugia malayi cyclin-dependent kinase 9 0.0165 0.009 0.009
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Echinococcus multilocularis expressed protein 0.0179 0.0129 0.0129
Schistosoma mansoni cell adhesion molecule 0.0402 0.0742 0.0742
Brugia malayi Cyclin, N-terminal domain containing protein 0.0883 0.2064 0.2064
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0217 0.0234 0.0234
Onchocerca volvulus 0.0703 0.157 0.7268
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3769 1 1
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0528 0.1088 0.1088
Brugia malayi casein kinase 1, delta 0.0234 0.0281 0.0281
Onchocerca volvulus 0.0703 0.157 0.7268
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0179 0.0129 0.0104
Toxoplasma gondii EGF family domain-containing protein 0.0381 0.0683 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.01 0.01
Schistosoma mansoni vam6/vps39 related 0.0241 0.0298 0.0298
Onchocerca volvulus 0.0277 0.0399 0.1803
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0274 0.0389 0.0389
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0381 0.0683 0.3131
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0499 0.1009 0.1009
Loa Loa (eye worm) TK protein kinase 0.0268 0.0373 0.0373
Echinococcus multilocularis down syndrome cell adhesion 0.0174 0.0114 0.0114
Echinococcus granulosus neuroglian 0.086 0.2 0.2
Plasmodium falciparum glutathione reductase 0.3769 1 1
Onchocerca volvulus 0.0241 0.0298 0.1331
Brugia malayi hypothetical protein 0.0141 0.0024 0.0024
Brugia malayi hypothetical protein 0.0208 0.021 0.021
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.03 0.046 0.046
Brugia malayi Protein kinase domain containing protein 0.0369 0.0651 0.0651
Loa Loa (eye worm) protein kinase domain-containing protein 0.0459 0.0899 0.0899
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0667 0.1469 0.1469
Echinococcus granulosus titin 0.0265 0.0364 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.0899 0.0899
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Brugia malayi SRC-1 0.0329 0.0542 0.0542
Brugia malayi STE20-like kinase MST 0.0553 0.1158 0.1158
Schistosoma mansoni serine/threonine protein kinase 0.0525 0.108 0.108
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Giardia lamblia Aurora kinase 0.0254 0.0334 0.066
Schistosoma mansoni netrin receptor unc5 0.0271 0.0381 0.0381
Schistosoma mansoni basigin related 0.0208 0.021 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.012 0.012
Schistosoma mansoni protein kinase 0.0234 0.0281 0.0281
Schistosoma mansoni cell adhesion molecule 0.0193 0.0168 0.0168
Echinococcus granulosus casein kinase I alpha 0.0234 0.0281 0.0281
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0759 0.1724 0.1724
Entamoeba histolytica protein kinase, putative 0.0186 0.0146 0.0617
Trypanosoma cruzi cdc2-related kinase 3 0.0256 0.0341 0.0316
Brugia malayi putative serine/threonine kinase SADA gamma 0.0169 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Echinococcus multilocularis epidermal growth factor receptor 0.0747 0.1691 0.1691
Brugia malayi probable protein kinase 0.0571 0.1205 0.1205
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0172 0.011 0.011
Onchocerca volvulus Putative cubilin 0.0381 0.0683 0.3131
Brugia malayi Furin-like cysteine rich region family protein 0.0747 0.1691 0.1691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0338 0.0564 0.0564
Onchocerca volvulus 0.0174 0.0114 0.0475
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0329 0.0542 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0334 0.0334
Schistosoma mansoni myosin-binding protein-related 0.0193 0.0168 0.0168
Plasmodium vivax ferrodoxin reductase, putative 0.0347 0.059 0.0478
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0169 0.0169
Trypanosoma brucei protein kinase, putative 0.0197 0.0178 0.0153
Giardia lamblia Kinase, CK1 Casein kinase 0.0234 0.0281 0.0488
Trichomonas vaginalis CK1 family protein kinase 0.0234 0.0281 0.0818
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Brugia malayi Calcium binding EGF domain containing protein 0.0381 0.0683 0.0683
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0582 0.1237 0.1237
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0248 0.0319 0.0319
Trypanosoma cruzi casein kinase, putative 0.0234 0.0281 0.0256
Echinococcus granulosus cGMP dependent protein kinase 1 0.0182 0.0136 0.0136
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0244 0.0306 0.0282
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Echinococcus multilocularis serine:threonine protein kinase 0.0246 0.0313 0.0313
Echinococcus granulosus protein tyrosine kinase 0.0621 0.1343 0.1343
Onchocerca volvulus 0.0163 0.0084 0.0335
Onchocerca volvulus 0.0194 0.0169 0.0729
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0331 0.0547 0.0523
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0334 0.0983
Echinococcus granulosus expressed protein 0.0179 0.0129 0.0129
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0129 0.0129
Echinococcus granulosus titin 0.0265 0.0364 0.0364
Onchocerca volvulus 0.0381 0.0683 0.3131
Echinococcus granulosus casein kinase i 0.0234 0.0281 0.0281
Leishmania major hypothetical protein, conserved 0.0347 0.059 0.0566
Giardia lamblia Kinase, CMGC DYRK 0.03 0.046 0.1067
Trichomonas vaginalis CAMK family protein kinase 0.0467 0.0922 0.2815
Echinococcus multilocularis titin 0.0174 0.0114 0.0114
Giardia lamblia Kinase, PLK 0.0582 0.1237 0.3575
Schistosoma mansoni glutamate synthase 0.0347 0.059 0.059
Trichomonas vaginalis STE family protein kinase 0.0186 0.0146 0.04
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0347 0.059 0.0478
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0293 0.0443 0.0419
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0182 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0241 0.0298 0.0298
Echinococcus granulosus protein jagged 1 0.0381 0.0683 0.0683
Trypanosoma cruzi cdc2-related kinase 3 0.0256 0.0341 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0402 0.0742 0.0742
Schistosoma mansoni sulfide quinone reductase 0.0347 0.059 0.059
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0277 0.0399 0.0399
Onchocerca volvulus Peroxidasin homolog 0.0174 0.0116 0.0482
Echinococcus granulosus mitogen activated protein kinase 3 0.0181 0.0133 0.0133
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0228 0.0263 0.0263
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0174 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.2028 0.5213 0.5213
Trichomonas vaginalis STE family protein kinase 0.0293 0.0443 0.1324
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.079 0.1808 0.1808
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0437 0.0837 0.0837
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Entamoeba histolytica protein kinase domain containing protein 0.0437 0.0837 0.3933
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0163 0.0084 0.0059
Echinococcus multilocularis PAK box P21 Rho binding 0.0139 0.0018 0.0018
Onchocerca volvulus Serine\/threonine kinase homolog 0.0582 0.1237 0.5715
Schistosoma mansoni tyrosine kinase 0.0373 0.0663 0.0663
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0329 0.0542 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0306 0.0306
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0169 0.01 0.0076
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0347 0.059 0.0566
Trypanosoma cruzi cdc2-related kinase 1 0.0256 0.0341 0.0316
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.03 0.046 0.0436
Echinococcus multilocularis serine threonine protein kinase 0.0435 0.0832 0.0832
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0341 0.0341
Brugia malayi Heparan sulfate 0.0208 0.021 0.021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0492 0.0991 0.0991
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0347 0.059 0.0566
Schistosoma mansoni protein kinase 0.033 0.0544 0.0544
Echinococcus granulosus hemicentin 1 0.0382 0.0688 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0436 0.0436
Echinococcus granulosus Immunoglobulin subtype 0.0208 0.021 0.021
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1306 0.3228 0.3211
Trypanosoma brucei SNF1-related protein kinases, putative 0.0169 0.01 0.0076
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0759 0.1724 0.1724
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0347 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0686 0.1522 0.1522
Echinococcus granulosus leucine rich repeat containing protein 4 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0329 0.0542 0.0542
Echinococcus multilocularis serine:threonine protein kinase N2 0.0347 0.059 0.059
Loa Loa (eye worm) TK/EGFR protein kinase 0.0747 0.1691 0.1691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus multilocularis roundabout 2 0.0402 0.0742 0.0742
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Loa Loa (eye worm) AUR protein kinase 0.0254 0.0334 0.0334
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0347 0.059 0.0566
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0347 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0703 0.157 0.157
Entamoeba histolytica protein kinase, putative 0.0197 0.0178 0.0768
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0133 0.0358
Echinococcus multilocularis 0.033 0.0544 0.0544
Brugia malayi Immunoglobulin I-set domain containing protein 0.0382 0.0688 0.0688
Echinococcus granulosus cyclin dependent kinase 9 0.0181 0.0135 0.0135
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.03 0.046 0.0436
Schistosoma mansoni protein kinase C mu 0.0469 0.0925 0.0925
Echinococcus granulosus calcium activated potassium channel 0.0291 0.0436 0.0436
Entamoeba histolytica protein kinase, putative 0.0263 0.0361 0.1647
Loa Loa (eye worm) hypothetical protein 0.0429 0.0815 0.0815
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0347 0.059 0.059
Trypanosoma brucei rac serine-threonine kinase, putative 0.0629 0.1367 0.1345
Echinococcus granulosus tyrosine protein kinase Srms 0.0585 0.1244 0.1244
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0319 0.0936
Brugia malayi Protein kinase c protein 2 0.0249 0.0322 0.0322
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0331 0.0547 0.0523
Echinococcus multilocularis protein jagged 2 0.0381 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase shark 0.0373 0.0663 0.0663
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Brugia malayi Protein kinase domain containing protein 0.0459 0.0899 0.0899
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0133 0.0358
Onchocerca volvulus 0.0141 0.0024 0.0056
Schistosoma mansoni hypothetical protein 0.0241 0.0298 0.0298
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0222 0.0246 0.0246
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0347 0.059 0.059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0209 0.0211 0.0211
Onchocerca volvulus Neurogenic locus notch homolog 0.0381 0.0683 0.3131
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0354 0.0609 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0436 0.0436
Echinococcus multilocularis ephrin type A receptor 4 A 0.0208 0.0208 0.0208
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1306 0.3228 0.3211
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0338 0.0564 0.0541
Entamoeba histolytica cyclin C, putative 0.0896 0.2099 1
Schistosoma mansoni protein kinase 0.0141 0.0025 0.0025
Schistosoma mansoni nephrin related 0.0174 0.0114 0.0114
Brugia malayi Cadherin domain containing protein 0.0381 0.0684 0.0684
Loa Loa (eye worm) cyclin C 0.1765 0.4491 0.4491
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0256 0.0341 0.0341
Schistosoma mansoni rap gtpase-activating protein 0.0241 0.0298 0.0298
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0254 0.0334 0.0219
Schistosoma mansoni vav2 0.0177 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Schistosoma mansoni cell adhesion molecule 0.0174 0.0114 0.0114
Trichomonas vaginalis CMGC family protein kinase 0.0256 0.0341 0.1005
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0347 0.059 0.0566
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0208 0.021 0.021
Schistosoma mansoni protein kinase 0.079 0.1808 0.1808
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0254 0.0334 0.0334
Leishmania major casein kinase, putative 0.0234 0.0281 0.0256
Brugia malayi Protein kinase domain containing protein 0.1189 0.2906 0.2906
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0202 0.0193 0.0193
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1282 0.3938
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0582 0.1237 0.1237
Onchocerca volvulus 0.0381 0.0683 0.3131
Onchocerca volvulus 0.0174 0.0114 0.0475
Brugia malayi SH2 domain containing protein 0.0141 0.0024 0.0024
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0347 0.059 0.0566
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0347 0.059 0.1781
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Toxoplasma gondii NADPH-glutathione reductase 0.1306 0.3228 0.3211
Entamoeba histolytica protein kinase, putative 0.0155 0.0063 0.0216
Echinococcus multilocularis hemicentin 1 0.0382 0.0688 0.0688
Giardia lamblia Kinase, CMGC CLK 0.0331 0.0547 0.1347
Toxoplasma gondii selenide, water dikinase 0.0347 0.059 0.0566
Schistosoma mansoni cell adhesion molecule 0.0402 0.0742 0.0742
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1306 0.3228 0.2803
Echinococcus granulosus tyrosine protein kinase Src42A 0.02 0.0187 0.0187
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0263 0.0361 0.0337
Entamoeba histolytica protein kinase, putative 0.0179 0.0129 0.0534
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1189 0.2906 0.2906
Brugia malayi Protein kinase domain containing protein 0.0433 0.0826 0.0826
Echinococcus multilocularis serine:threonine protein kinase 38 0.0347 0.059 0.059
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0234 0.0281 0.0281
Schistosoma mansoni nephrin 0.0402 0.0742 0.0742
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0307 0.0482 0.0482
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0208 0.021 0.021
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0217 0.0234 0.021
Echinococcus granulosus N chimaerin 0.0161 0.0079 0.0079
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0471 0.0932 0.0932
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0256 0.0341 0.0316
Echinococcus multilocularis cyclin dependent kinase 1 0.0256 0.0341 0.0341
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0391 0.0712 0.0712
Brugia malayi Protein kinase domain containing protein 0.0141 0.0024 0.0024
Schistosoma mansoni protein kinase 0.0186 0.0146 0.0146
Schistosoma mansoni septate junction protein 0.0382 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0241 0.0298 0.0298
Onchocerca volvulus 0.0193 0.0168 0.0727
Echinococcus multilocularis insulin growth factor binding 0.0174 0.0114 0.0114
Echinococcus granulosus protein kinase C gamma type 0.0435 0.0832 0.0832
Loa Loa (eye worm) hypothetical protein 0.0208 0.021 0.021
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2028 0.5213 0.5213
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0172 0.011 0.011
Brugia malayi P38 map kinase family protein 2 0.0343 0.0579 0.0579
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0174 0.0114 0.0114
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0256 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0437 0.0837 0.0837
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0217 0.0234 0.0234
Schistosoma mansoni hemicentin 0.0193 0.0168 0.0168
Onchocerca volvulus 0.0299 0.0458 0.2078
Echinococcus granulosus fibropellin Ia 0.0381 0.0683 0.0683
Schistosoma mansoni cell adhesion molecule 0.0208 0.021 0.021
Onchocerca volvulus 0.0174 0.0116 0.0482
Loa Loa (eye worm) TK protein kinase 0.0331 0.0546 0.0546
Entamoeba histolytica protein kinase, putative 0.0254 0.0334 0.1517
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0217 0.0234 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0399 0.183
Trichomonas vaginalis CMGC family protein kinase 0.0256 0.0341 0.1005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0222 0.0246 0.0246
Brugia malayi protein kinase C3,putative 0.034 0.0571 0.0571
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0169 0.0469
Onchocerca volvulus 0.0381 0.0683 0.3131
Schistosoma mansoni hypothetical protein 0.0347 0.059 0.059
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0471 0.0932 0.0932
Brugia malayi Protein kinase domain containing protein 0.0467 0.0922 0.0922
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0325 0.053 0.053
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1064 0.2563 0.2563
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0181 0.0133 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0141 0.0024 0.0024
Onchocerca volvulus 0.0174 0.0114 0.0475
Loa Loa (eye worm) hypothetical protein 0.0226 0.0259 0.0259
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0759 0.1724 0.7988
Echinococcus granulosus serine:threonine protein kinase 0.0246 0.0313 0.0313
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.033 0.0544 0.0544
Plasmodium vivax apical sushi protein, putative 0.0703 0.157 0.147
Onchocerca volvulus 0.0141 0.0024 0.0056
Echinococcus multilocularis Immunoglobulin subtype 0.0208 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0138 0.0015 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0161 0.0079 0.0079
Echinococcus multilocularis roundabout 2 0.1088 0.2627 0.2627
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0136 0.0136
Echinococcus granulosus basement membrane specific heparan sulfate 0.0208 0.021 0.021
Echinococcus granulosus Immunoglobulin 0.0208 0.021 0.021
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0277 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0414 0.0774 0.0774
Schistosoma mansoni tyrosine kinase 0.0138 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.0916 0.0916
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0174 0.0114 0.0114
Brugia malayi hypothetical protein 0.0479 0.0953 0.0953
Plasmodium vivax casein kinase 1, putative 0.0234 0.0281 0.0166
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683
Schistosoma mansoni titin 0.0174 0.0114 0.0114
Echinococcus multilocularis dual specificity 0.03 0.046 0.046
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0208 0.021 0.021
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0217 0.0234 0.0234
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1306 0.3228 1
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.03 0.046 0.046
Echinococcus multilocularis epidermal growth factor receptor 0.0521 0.1069 0.1069
Echinococcus multilocularis mitogen activated protein kinase 0.0181 0.0133 0.0133
Schistosoma mansoni septate junction protein 0.0381 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0186 0.0146 0.0146
Brugia malayi Disorganized muscle protein 1 0.0174 0.0114 0.0114
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1636 0.4136 0.4136
Echinococcus multilocularis rho associated protein kinase 0.07 0.1562 0.1562
Echinococcus granulosus defective proboscis extension response 0.0686 0.1522 0.1522
Plasmodium falciparum glycogen synthase kinase 3 0.0277 0.0399 0.0375
Loa Loa (eye worm) casein kinase 0.0388 0.0703 0.0703
Schistosoma mansoni serine/threonine protein kinase 0.1027 0.246 0.246
Echinococcus multilocularis NCK adaptor protein 0.0134 0.0006 0.0006
Echinococcus multilocularis casein kinase I delta 0.0234 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.026 0.0351 0.0351
Echinococcus multilocularis slit 2 protein 0.0429 0.0815 0.0815
Loa Loa (eye worm) hypothetical protein 0.0402 0.0742 0.0742
Echinococcus granulosus roundabout 2 0.0402 0.0742 0.0742
Entamoeba histolytica protein kinase domain containing protein 0.0165 0.009 0.0344
Brugia malayi Protein kinase domain containing protein 0.0256 0.0341 0.0341
Echinococcus multilocularis aurora kinase A 0.0254 0.0334 0.0334
Schistosoma mansoni g1/s-specific cyclin C 0.1765 0.4491 0.4491
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Echinococcus multilocularis dual specificity protein kinase clk2 0.0331 0.0547 0.0547
Echinococcus granulosus dual specificity 0.03 0.046 0.046
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Echinococcus multilocularis cyclin dependent kinase 5 0.0256 0.0341 0.0341
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0347 0.059 0.1781
Schistosoma mansoni tyrosine kinase 0.0329 0.0542 0.0542
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0934 0.2206 0.2206
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0347 0.059 0.0566
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Echinococcus multilocularis netrin receptor unc 5 0.0271 0.0381 0.0381
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1306 0.3228 0.3211
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0686 0.1522 0.1522
Brugia malayi Temporarily assigned gene name protein 59 0.0241 0.0298 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.03 0.046 0.1377
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0347 0.059 0.059
Schistosoma mansoni hypothetical protein 0.0219 0.0239 0.0239
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0114 0.0114
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0347 0.059 0.059
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.03 0.046 0.0436
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1306 0.3228 0.3148
Leishmania major protein kinase, putative 0.0183 0.0138 0.0114
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0729 0.1641 0.1641
Giardia lamblia Kinase, CAMK CAMKL 0.0185 0.0146 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0582 0.1237 0.3798
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0347 0.059 0.0566
Loa Loa (eye worm) programmed cell death 8 0.0347 0.059 0.059
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0141 0.0024 0.0031
Entamoeba histolytica serine/threonine protein kinase, putative 0.0169 0.01 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0547 0.0547
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0347 0.059 0.059
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0208 0.021 0.021
Brugia malayi EGF-like domain containing protein 0.0381 0.0683 0.0683
Plasmodium falciparum ferrodoxin reductase-like protein 0.0347 0.059 0.0566
Echinococcus multilocularis cyclin dependent kinase 1 0.0256 0.0341 0.0341
Echinococcus multilocularis tyrosine protein kinase HCK 0.0197 0.0178 0.0178
Treponema pallidum NADH oxidase 0.1306 0.3228 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Brugia malayi Protein kinase domain containing protein 0.0179 0.0129 0.0129
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0234 0.0281 0.0281
Schistosoma mansoni serine/threonine-protein kinase 0.0354 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Onchocerca volvulus Tyrosine kinase homolog 0.0916 0.2155 1
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0312 0.0495 0.0495
Echinococcus granulosus netrin receptor unc 5 0.0271 0.0381 0.0381
Trypanosoma brucei casein kinase I, isoform 2 0.0234 0.0281 0.0256
Echinococcus granulosus tyrosine protein kinase Src42A 0.0329 0.0542 0.0542
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0263 0.0361 0.0337
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0293 0.0443 0.033
Echinococcus multilocularis c src tyrosine kinase 0.0202 0.0193 0.0193
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Echinococcus granulosus c-Jun N-terminal kinases 0.0569 0.1202 0.1202
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0883 0.2064 0.2064
Echinococcus multilocularis lachesin 0.0382 0.0688 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0609 0.0609
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1306 0.3228 0.3228
Schistosoma mansoni hypothetical protein 0.0381 0.0683 0.0683
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0331 0.0547 0.0523
Loa Loa (eye worm) AGC/NDR protein kinase 0.0347 0.059 0.059
Echinococcus multilocularis notch 0.0381 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase Blk 0.0268 0.0373 0.0373
Plasmodium falciparum apical sushi protein 0.0703 0.157 0.1549
Leishmania major protein kinase A catalytic subunit 0.0244 0.0306 0.0282
Echinococcus granulosus cyclin dependent kinase 5 0.0256 0.0341 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.1147 0.1147
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0256 0.0341 0.0316
Entamoeba histolytica protein kinase, putative 0.0176 0.012 0.0488
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0347 0.059 0.059
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1306 0.3228 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0244 0.0306 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0334 0.0983
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0382 0.0688 0.0688
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0277 0.0399 0.0375
Echinococcus granulosus lachesin 0.0382 0.0688 0.0688
Trichomonas vaginalis STE family protein kinase 0.0186 0.0146 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.059 0.059
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.044 0.0845 0.0845
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0234 0.0281 0.0281
Echinococcus multilocularis cyclin dependent kinase 9 0.0181 0.0135 0.0135
Loa Loa (eye worm) notch protein 0.0381 0.0683 0.0683
Echinococcus multilocularis tyrosine protein kinase Abl 0.0202 0.0193 0.0193
Onchocerca volvulus 0.0174 0.0114 0.0475
Entamoeba histolytica cell division protein kinase 2, putative 0.0256 0.0341 0.1549
Entamoeba histolytica casein kinase, putative 0.0216 0.023 0.1018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0234 0.0234
Plasmodium falciparum protein serine/threonine kinase-1 0.0331 0.0547 0.0523
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0347 0.059 0.059
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0312 0.0494 0.0494
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0381 0.0683 0.0683
Giardia lamblia Kinase, CMGC CDK 0.0256 0.0341 0.0682
Loa Loa (eye worm) hypothetical protein 0.0192 0.0165 0.0165
Echinococcus granulosus tyrosine protein kinase HCK 0.0197 0.0178 0.0178
Onchocerca volvulus 0.0174 0.0114 0.0475
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0717 0.1608 0.1608
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0241 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0185 0.0144 0.0144
Trypanosoma brucei protein kinase, putative 0.0277 0.0399 0.0375
Echinococcus multilocularis neuroglian 0.086 0.2 0.2
Entamoeba histolytica protein kinase domain containing protein 0.03 0.046 0.2123
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0208 0.021 0.021
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0244 0.0306 0.0282
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0476 0.0945 0.0945
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0381 0.0381
Entamoeba histolytica PH domain containing protein kinase, putative 0.0354 0.0609 0.2841
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0849 0.1971 0.1971
Echinococcus granulosus slit 2 protein 0.0429 0.0815 0.0815
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0331 0.0547 0.0523
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0415 0.0779 0.0779
Echinococcus granulosus cyclin dependent kinase 0.0256 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0219 0.0239 0.0239
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0569 0.1202 0.1202
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0169 0.01 0.0076
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0479 0.0953 0.0953
Schistosoma mansoni titin 0.0174 0.0114 0.0114
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0216 0.023 0.023
Echinococcus granulosus casein kinase I alpha 0.0234 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0401 0.0739 0.0739
Echinococcus multilocularis 0.0174 0.0114 0.0114
Trypanosoma cruzi cdc2-related kinase 1 0.0256 0.0341 0.0316
Plasmodium vivax calcium-dependent protein kinase, putative 0.0217 0.0234 0.0119
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0347 0.059 0.0566
Loa Loa (eye worm) hypothetical protein 0.1068 0.2573 0.2573
Schistosoma mansoni serine/threonine-protein kinase 0.0354 0.0609 0.0609
Echinococcus multilocularis tyrosine protein kinase Srms 0.0268 0.0373 0.0373
Brugia malayi Myb-like DNA-binding domain containing protein 0.0174 0.0114 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0185 0.0146 0.0029
Entamoeba histolytica PH domain containing protein kinase, putative 0.026 0.0351 0.1601
Plasmodium falciparum casein kinase 2, alpha subunit 0.0216 0.023 0.0205
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0391 0.0712 0.0712
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0244 0.0306 0.0282
Echinococcus granulosus hypothetical protein 0.026 0.0351 0.0351
Schistosoma mansoni titin 0.0193 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0382 0.0688 0.0688
Echinococcus granulosus fibroblast growth factor receptor 4 0.0391 0.0712 0.0712
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Brugia malayi Sushi domain 0.0703 0.157 0.157
Trypanosoma brucei NADH dehydrogenase 0.0347 0.059 0.0566
Brugia malayi kettin 0.0174 0.0114 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Leishmania major casein kinase II, putative 0.0216 0.023 0.0205
Echinococcus multilocularis mitogen activated protein kinase 11 0.0343 0.0579 0.0579
Echinococcus granulosus protein kinase shaggy 0.0277 0.0399 0.0399
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0168 0.0168
Plasmodium vivax glutathione reductase, putative 0.3769 1 1
Toxoplasma gondii rhoptry neck protein RON1 0.0703 0.157 0.1549
Echinococcus granulosus neurogenic locus protein delta 0.0381 0.0683 0.0683
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0432 0.0825 0.0825
Trypanosoma cruzi Protein kinase B 0.0354 0.0609 0.0586
Plasmodium falciparum NIMA related kinase 1 0.0293 0.0443 0.0419
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0174 0.0114 0.0114
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0883 0.2064 0.2064
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0175 0.0117 0.0092
Echinococcus multilocularis casein kinase I gamma 0.0459 0.0899 0.0899
Echinococcus granulosus dual specificity protein kinase clk2 0.0331 0.0547 0.0547
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1306 0.3228 0.3148
Schistosoma mansoni titin 0.0382 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0174 0.0114 0.0114
Giardia lamblia Kinase, AGC PKA 0.0338 0.0564 0.1404
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0934 0.2206 0.2206
Loa Loa (eye worm) hypothetical protein 0.0241 0.0298 0.0298
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Echinococcus multilocularis calcium activated potassium channel 0.0291 0.0436 0.0436
Schistosoma mansoni hypothetical protein 0.0174 0.0114 0.0114
Echinococcus granulosus C type lectin domian containing protein 0.0703 0.157 0.157
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0353 0.0607 0.0607
Echinococcus granulosus protein kinase 0.033 0.0544 0.0544
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0582 0.1237 0.1215
Schistosoma mansoni glutamate synthase 0.0347 0.059 0.059
Onchocerca volvulus 0.0174 0.0114 0.0475
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.023 0.066
Toxoplasma gondii AGC kinase 0.0244 0.0306 0.0282
Brugia malayi hypothetical protein 0.0703 0.157 0.157
Trypanosoma cruzi trypanothione reductase, putative 0.1306 0.3228 0.3211
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0329 0.0542 0.0542
Echinococcus multilocularis Immunoglobulin 0.0686 0.1522 0.1522
Echinococcus granulosus serine:threonine protein kinase 3 0.0553 0.1158 0.1158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1306 0.3228 0.3211
Brugia malayi pregnancy-associated plasma protein-A 0.0703 0.157 0.157
Schistosoma mansoni growth factor receptor-bound protein 0.0134 0.0006 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0629 0.1367 0.4203
Schistosoma mansoni serine/threonine kinase 0.0484 0.0967 0.0967
Trichomonas vaginalis mercuric reductase, putative 0.1306 0.3228 1
Brugia malayi Protein kinase domain containing protein 0.079 0.1808 0.1808
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.01 0.0256
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0181 0.0133 0.0108
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1306 0.3228 0.2803
Brugia malayi Protein kinase domain containing protein 0.0263 0.0361 0.0361
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0244 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0169 0.01 0.01
Giardia lamblia Kinase, NEK 0.0293 0.0443 0.1013
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0254 0.0334 0.1517
Loa Loa (eye worm) hypothetical protein 0.0381 0.0683 0.0683

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 12.3 uM Inhibitory activity against tetracycline uptake in everted membrane vesicles derived from Tc-resistant Escherichia coli bearing class B tetracycline resistance efflux protein (Tet) ChEMBL. 8176712
IC50 (functional) = 12.3 uM Inhibitory activity against tetracycline uptake in everted membrane vesicles derived from Tc-resistant Escherichia coli bearing class B tetracycline resistance efflux protein (Tet) ChEMBL. 8176712

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Escherichia coli ChEMBL23 8176712

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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