Detailed information for compound 369508

Basic information

Technical information
  • TDR Targets ID: 369508
  • Name: 4-(2-chloro-4-fluorophenyl)-5-(3-propan-2-yl- [1,2,4]triazolo[4,3-a]pyridin-6-yl)-1,3-oxazo le
  • MW: 356.781 | Formula: C18H14ClFN4O
  • H donors: 0 H acceptors: 3 LogP: 4.8 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(c(c1)Cl)c1ncoc1c1ccc2n(c1)c(nn2)C(C)C
  • InChi: 1S/C18H14ClFN4O/c1-10(2)18-23-22-15-6-3-11(8-24(15)18)17-16(21-9-25-17)13-5-4-12(20)7-14(13)19/h3-10H,1-2H3
  • InChiKey: DSKANFBRGYWCHD-UHFFFAOYSA-N  


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Synonyms

  • 4-(2-chloro-4-fluoro-phenyl)-5-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxazole
  • 4-(2-chloro-4-fluorophenyl)-5-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxazole
  • 4-(2-chloro-4-fluoro-phenyl)-5-(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-1,3-oxazole
  • 6-[4-(2-chloro-4-fluorophenyl)-1,3-oxazol-5-yl]-3-propan-2-yl-[1,2,4]triazolo[4,5-a]pyridine
  • 6-[4-(2-chloro-4-fluoro-phenyl)oxazol-5-yl]-3-isopropyl-[1,2,4]triazolo[4,5-a]pyridine
  • 6-[4-(2-chloro-4-fluorophenyl)-5-oxazolyl]-3-isopropyl-[1,2,4]triazolo[4,5-a]pyridine
  • 6-[4-(2-chloro-4-fluoro-phenyl)-1,3-oxazol-5-yl]-3-propan-2-yl-[1,2,4]triazolo[4,5-a]pyridine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protein kinase C, alpha Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 12 Starlite/ChEMBL References
Homo sapiens casein kinase 2, alpha 1 polypeptide References
Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 5 Starlite/ChEMBL References
Homo sapiens casein kinase 2, beta polypeptide Starlite/ChEMBL References
Homo sapiens Rho-associated, coiled-coil containing protein kinase 2 Starlite/ChEMBL References
Homo sapiens casein kinase 2, alpha prime polypeptide References
Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 2 Starlite/ChEMBL References
Homo sapiens LCK proto-oncogene, Src family tyrosine kinase Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, alpha 1 catalytic subunit References
Homo sapiens serum/glucocorticoid regulated kinase 1 Starlite/ChEMBL References
Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, alpha 2 catalytic subunit References
Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 References
Homo sapiens glycogen synthase kinase 3 beta Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 8 Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, beta 1 non-catalytic subunit References
Homo sapiens mitogen-activated protein kinase 10 References
Homo sapiens v-akt murine thymoma viral oncogene homolog 1 Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, gamma 3 non-catalytic subunit Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 13 Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase-activated protein kinase 2 Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 14 Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, gamma 1 non-catalytic subunit References
Homo sapiens checkpoint kinase 1 Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase-activated protein kinase 5 Starlite/ChEMBL References
Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 1 Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit References
Homo sapiens mitogen-activated protein kinase kinase 1 Starlite/ChEMBL References
Homo sapiens c-src tyrosine kinase Starlite/ChEMBL References
Homo sapiens protein kinase, AMP-activated, beta 2 non-catalytic subunit References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans protein serine/threonine kinase Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans Casein kinase II, regulatory (beta-prime) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum ko:K03097 casein kinase 2, alpha polypeptide, putative Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K04440 c-Jun N-terminal kinase, putative Get druggable targets OG5_129677 All targets in OG5_129677
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Theileria parva 5'-AMP-activated protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K07200 5'-AMP-activated protein kinase, regulatory gamma subunit, putative Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127304 All targets in OG5_127304
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum ko:K04443 mitogen-activated protein kinase-activated protein kinase 2, putative Get druggable targets OG5_131483 All targets in OG5_131483
Trypanosoma cruzi Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Babesia bovis casein kinase II, alpha chain (CK II) Get druggable targets OG5_126901 All targets in OG5_126901
Giardia lamblia Kinase, CMGC CK2 Get druggable targets OG5_126901 All targets in OG5_126901
Brugia malayi map kinase activated protein kinase protein 2 Get druggable targets OG5_131483 All targets in OG5_131483
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129482 All targets in OG5_129482
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Tyrosine-protein kinase CSK, putative Get druggable targets OG5_133402 All targets in OG5_133402
Trypanosoma brucei gambiense protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) CMGC/CK2 protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_130454 All targets in OG5_130454
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis serine/threonine-protein kinase, putative Get druggable targets OG5_128437 All targets in OG5_128437
Giardia lamblia Kinase, CAMK CAMKL Get druggable targets OG5_126655 All targets in OG5_126655
Loa Loa (eye worm) SH2 domain-containing protein Get druggable targets OG5_133402 All targets in OG5_133402
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Dual specificity mitogen-activated protein kinase kinase 1, putative Get druggable targets OG5_127304 All targets in OG5_127304
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis dual specificity mitogen activated protein Get druggable targets OG5_127304 All targets in OG5_127304
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Cryptosporidium hominis gal83 protein Get druggable targets OG5_127587 All targets in OG5_127587
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase Get druggable targets OG5_131483 All targets in OG5_131483
Toxoplasma gondii CMGC kinase, CK2 family Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans similar to S. cerevisiae HSL1 (YKL101W) serine/threonine-protein kinase involved in cell cycle control Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica casein kinase, putative Get druggable targets OG5_126901 All targets in OG5_126901
Trypanosoma congolense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania donovani casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Theileria parva casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Cryptosporidium parvum casein kinase II, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus casein kinase ii subunit beta Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania mexicana mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei gambiense serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium yoelii casein kinase ii beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_127587 All targets in OG5_127587
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Plasmodium vivax casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) TK/CSK protein kinase Get druggable targets OG5_133402 All targets in OG5_133402
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans glucose repression Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative Get druggable targets OG5_127587 All targets in OG5_127587
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein Get druggable targets OG5_127587 All targets in OG5_127587
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania braziliensis rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Dual specificity mitogen-activated protein kinase kinase 2, putative Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania infantum protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium knowlesi serine/threonine protein kinase KIN, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum AMP-activated protein kinase beta chain (has isoamylase N-terminal domain) Get druggable targets OG5_127587 All targets in OG5_127587
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Plasmodium vivax unspecified product Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Candida albicans bud neck kinase Get druggable targets OG5_126655 All targets in OG5_126655
Neospora caninum hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani rac serine-threonine kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Trypanosoma congolense casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans Casein kinase II, regulatory (beta-prime) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_133402 All targets in OG5_133402
Brugia malayi Protein kinase c protein 2 Get druggable targets OG5_129482 All targets in OG5_129482
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis casein kinase ii subunit alpha Get druggable targets OG5_126901 All targets in OG5_126901
Schistosoma japonicum Calcium-dependent protein kinase C, putative Get druggable targets OG5_129482 All targets in OG5_129482
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Toxoplasma gondii casein kinase ii regulatory subunit protein Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) 5'-AMP-activated protein kinase Get druggable targets OG5_127587 All targets in OG5_127587
Leishmania braziliensis mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 Get druggable targets OG5_127304 All targets in OG5_127304
Toxoplasma gondii histone kinase SNF1, putative Get druggable targets OG5_126655 All targets in OG5_126655
Babesia bovis casein kinase II beta 4 subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Casein kinase II, regulatory (beta) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase Get druggable targets OG5_130454 All targets in OG5_130454
Leishmania braziliensis protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis MAP kinase activated protein kinase 2 Get druggable targets OG5_131483 All targets in OG5_131483
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium knowlesi casein kinase 2, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Serine/threonine-protein kinase Chk1, putative Get druggable targets OG5_130454 All targets in OG5_130454
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania braziliensis serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 Get druggable targets OG5_127304 All targets in OG5_127304
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus 5' AMP activated protein kinase catalytic Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative Get druggable targets OG5_128437 All targets in OG5_128437
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_127587 All targets in OG5_127587
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Onchocerca volvulus Casein kinase II subunit beta homolog Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium berghei casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum ko:K07198 5'-AMP-activated protein kinase, catalytic alpha subunit, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine:threonine kinase SAD 1 Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus MAP kinase activated protein kinase 2 Get druggable targets OG5_131483 All targets in OG5_131483
Leishmania mexicana protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans similar to S. cerevisiae HSL1 (YKL101W) serine/threonine-protein kinase involved in cell cycle control Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans likely MAP kinase kinase that can functionally substitute for S. cerevisiae STE7 (YDL159W) Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum protein kinase NPK2 Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_127587 All targets in OG5_127587
Leishmania infantum casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni protein kinase subunit gamma Get druggable targets OG5_128342 All targets in OG5_128342
Echinococcus granulosus Protein kinase C brain isozyme Get druggable targets OG5_129482 All targets in OG5_129482
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_133402 All targets in OG5_133402
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Cryptosporidium parvum OSK4, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum 5'-AMP-activated protein kinase subunit gamma-2, putative Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium hominis protein kinase domain Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans likely protein kinase similar to S. cerevisiae CKA1 (YIL035C) alpha subunit of protein kinase 2, aka casein kinase II Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Theileria parva hypothetical protein Get druggable targets OG5_127587 All targets in OG5_127587
Echinococcus granulosus mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis c src tyrosine kinase Get druggable targets OG5_133402 All targets in OG5_133402
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium hominis protein kinase NPK2 (EC 2.7.1.-) Get druggable targets OG5_127304 All targets in OG5_127304
Brugia malayi ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Brugia malayi Csnk2b protein Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, STE STE20 Get druggable targets OG5_127304 All targets in OG5_127304
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit Get druggable targets OG5_128342 All targets in OG5_128342
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) loechrig isoform VII Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum HD domain-containing protein 2 homolog, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127304 All targets in OG5_127304
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Babesia bovis hypothetical protein Get druggable targets OG5_127587 All targets in OG5_127587
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K04441 p38 MAP kinase, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani 5'-AMP-activated protein kinase subunit beta, putative Get druggable targets OG5_127587 All targets in OG5_127587
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma Get druggable targets OG5_128342 All targets in OG5_128342
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Cryptosporidium parvum putative protein kinase CK2 regulatory subunit CK2B1 Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania mexicana serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Cryptosporidium parvum putative casein kinase II regulatory subunit; besthit Pf 23508244 Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Protein kinase C alpha type, putative Get druggable targets OG5_129482 All targets in OG5_129482
Candida albicans protein kinase C similar to S. cerevisiae PKC1 (YBL105C) Get druggable targets OG5_129482 All targets in OG5_129482
Echinococcus multilocularis serine threonine protein kinase Get druggable targets OG5_129482 All targets in OG5_129482
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Schistosoma japonicum Rho-associated protein kinase 1, putative Get druggable targets OG5_131020 All targets in OG5_131020
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi putative serine/threonine kinase SADA gamma Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis casein kinase ii subunit beta Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania major hypothetical protein, conserved Get druggable targets OG5_127587 All targets in OG5_127587
Neospora caninum hypothetical protein Get druggable targets OG5_126901 All targets in OG5_126901
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase Get druggable targets OG5_129482 All targets in OG5_129482
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Onchocerca volvulus Casein kinase II subunit beta homolog Get druggable targets OG5_126846 All targets in OG5_126846
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase Get druggable targets OG5_127304 All targets in OG5_127304
Echinococcus granulosus RNA directed DNA polymerase Get druggable targets OG5_129482 All targets in OG5_129482
Echinococcus granulosus c-Jun N-terminal kinases Get druggable targets OG5_129677 All targets in OG5_129677
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_131020 All targets in OG5_131020
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis Protein kinase C, brain isozyme Get druggable targets OG5_129482 All targets in OG5_129482
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Schistosoma japonicum Protein kinase C alpha type, putative Get druggable targets OG5_129482 All targets in OG5_129482
Trypanosoma brucei gambiense protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Brugia malayi SH2 domain containing protein Get druggable targets OG5_133402 All targets in OG5_133402
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129482 All targets in OG5_129482
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus protein kinase C gamma type Get druggable targets OG5_129482 All targets in OG5_129482
Trypanosoma congolense mitogen-activated protein kinase kinase 5 Get druggable targets OG5_127304 All targets in OG5_127304
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans likely MAP kinase kinase that can functionally substitute for S. cerevisiae STE7 (YDL159W) Get druggable targets OG5_127304 All targets in OG5_127304
Plasmodium berghei casein kinase 2, alpha subunit Get druggable targets OG5_126901 All targets in OG5_126901
Leishmania infantum protein kinase ck2 regulatory subunit, putative Get druggable targets OG5_126846 All targets in OG5_126846
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum expressed protein Get druggable targets OG5_127587 All targets in OG5_127587
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative Get druggable targets OG5_128437 All targets in OG5_128437
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Babesia bovis protein kinase CK2 regulatory subunit CK2B1 Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis RNA directed DNA polymerase Get druggable targets OG5_129482 All targets in OG5_129482
Plasmodium falciparum serine/threonine protein kinase KIN Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum hypothetical protein Get druggable targets OG5_127587 All targets in OG5_127587
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_131483 All targets in OG5_131483
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania donovani serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus casein kinase ii subunit alpha Get druggable targets OG5_126901 All targets in OG5_126901
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans protein kinase C similar to S. cerevisiae PKC1 (YBL105C) Get druggable targets OG5_129482 All targets in OG5_129482
Leishmania donovani mitogen-activated protein kinase kinase 5 Get druggable targets OG5_127304 All targets in OG5_127304
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans corresponds to C-terminus of S. cerevisiae SNF4 and allelic CaP19.13191 Get druggable targets OG5_128342 All targets in OG5_128342
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_127587 All targets in OG5_127587
Loa Loa (eye worm) Csnk2b protein Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni protein kinase Get druggable targets OG5_127304 All targets in OG5_127304
Candida albicans protein serine/threonine kinase Get druggable targets OG5_126655 All targets in OG5_126655
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Plasmodium berghei casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum IPR000719,Protein kinase,domain-containing Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Theileria parva casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Leishmania mexicana casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Plasmodium knowlesi casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein Get druggable targets OG5_127587 All targets in OG5_127587
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus c src tyrosine kinase Get druggable targets OG5_133402 All targets in OG5_133402
Plasmodium yoelii Protein kinase domain Get druggable targets OG5_126901 All targets in OG5_126901
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Casein kinase II, alpha chain Get druggable targets OG5_126901 All targets in OG5_126901
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium yoelii protein kinase Ck2-beta Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Leishmania donovani SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans member of the HOG1 MAPK cascade Get druggable targets OG5_127304 All targets in OG5_127304
Echinococcus multilocularis tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative Get druggable targets OG5_127587 All targets in OG5_127587
Trypanosoma brucei gambiense casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129482 All targets in OG5_129482
Schistosoma japonicum IPR000719,Protein kinase;IPR011009,Protein kinase-like,domain-containing Get druggable targets OG5_128147 All targets in OG5_128147
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Schistosoma japonicum Serine/threonine-protein kinase minibrain, putative Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania donovani Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis c Jun NH2 terminal kinase Get druggable targets OG5_129677 All targets in OG5_129677
Leishmania mexicana protein kinase, putative,mitogen activated protein kinase, putative Get druggable targets OG5_127304 All targets in OG5_127304
Candida albicans glucose repression Get druggable targets OG5_127587 All targets in OG5_127587
Trypanosoma congolense Casein kinase II subunit beta, putative Get druggable targets OG5_126846 All targets in OG5_126846
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum IPR000477,RNA-directed DNA polymerase (Reverse transcriptase),domain-containing Get druggable targets OG5_129482 All targets in OG5_129482
Schistosoma japonicum ko:K03115 casein kinase 2, beta polypeptide, putative Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania infantum mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 Get druggable targets OG5_127304 All targets in OG5_127304
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus dual specificity mitogen activated protein Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans glucose repression Get druggable targets OG5_127587 All targets in OG5_127587
Leishmania infantum rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 Get druggable targets OG5_127304 All targets in OG5_127304
Leishmania infantum mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative Get druggable targets OG5_127587 All targets in OG5_127587
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K08796 BR serine/threonine kinase, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_127304 All targets in OG5_127304
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense protein kinase, putative,MAP kinase kinase, putative Get druggable targets OG5_127304 All targets in OG5_127304
Schistosoma japonicum Ribosomal protein S6 kinase alpha-2, putative Get druggable targets OG5_128147 All targets in OG5_128147
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi P38 map kinase family protein 2 Get druggable targets OG5_128610 All targets in OG5_128610
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum MAP/microtubule affinity-regulating kinase 4, putative Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma brucei Casein kinase II Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans release from glucose repression, invertase expression Get druggable targets OG5_128342 All targets in OG5_128342
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Plasmodium falciparum casein kinase II beta chain Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni casein kinase II beta subunit Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans Casein kinase II, regulatory (beta) subunit Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma mansoni protein kinase subunit beta Get druggable targets OG5_127587 All targets in OG5_127587
Loa Loa (eye worm) AGC/RSK/RSK protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax casein kinase 2, alpha subunit, putative Get druggable targets OG5_126901 All targets in OG5_126901
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans Casein kinase II alpha' subunit Get druggable targets OG5_126901 All targets in OG5_126901
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Stress-activated protein kinase jnk-1 Get druggable targets OG5_129677 All targets in OG5_129677
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Babesia bovis cAMP-dependent protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma japonicum IPR000164,Histone H3;IPR009072,Histone-fold,domain-containing Get druggable targets OG5_129677 All targets in OG5_129677
Candida albicans Casein kinase II alpha' subunit Get druggable targets OG5_126901 All targets in OG5_126901
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum expressed protein Get druggable targets OG5_127901 All targets in OG5_127901
Theileria parva casein kinase II, alpha chain Get druggable targets OG5_126901 All targets in OG5_126901
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum casein kinase 2, alpha subunit Get druggable targets OG5_126901 All targets in OG5_126901
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis 5' AMP activated protein kinase catalytic Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Schistosoma japonicum Protein kinase C gamma type, putative Get druggable targets OG5_129482 All targets in OG5_129482
Echinococcus multilocularis telomerase reverse transcriptase subunit Get druggable targets OG5_129482 All targets in OG5_129482
Trichomonas vaginalis casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii ck2 beta subunit Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus granulosus rho-associated protein kinase 1 Get druggable targets OG5_131020 All targets in OG5_131020
Echinococcus granulosus AMPK beta subunit Get druggable targets OG5_127587 All targets in OG5_127587
Onchocerca volvulus Alicorn homolog Get druggable targets OG5_127587 All targets in OG5_127587
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania mexicana rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Giardia lamblia Kinase, AGC AKT Get druggable targets OG5_128147 All targets in OG5_128147
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_130454 All targets in OG5_130454
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani 5'-AMP-activated protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126655 All targets in OG5_126655
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis AMPK beta subunit Get druggable targets OG5_127587 All targets in OG5_127587
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit Get druggable targets OG5_127587 All targets in OG5_127587
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum casein kinase II beta chain, putative Get druggable targets OG5_126846 All targets in OG5_126846
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica casein kinase II regulatory subunit family protein Get druggable targets OG5_126846 All targets in OG5_126846
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium hominis protein kinase Ck2-beta Get druggable targets OG5_126846 All targets in OG5_126846
Loa Loa (eye worm) AGC/RSK/MSK protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Plasmodium vivax serine/threonine protein kinase KIN, putative Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma Get druggable targets OG5_128342 All targets in OG5_128342
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis tyrosine protein kinase csk Get druggable targets OG5_133402 All targets in OG5_133402
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129482 All targets in OG5_129482
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126655 All targets in OG5_126655
Candida albicans bud neck kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum YOR039Wp-like protein, related Get druggable targets OG5_126846 All targets in OG5_126846
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126901 All targets in OG5_126901
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Echinococcus granulosus mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Echinococcus multilocularis serine:threonine kinase SAD 1 Get druggable targets OG5_126655 All targets in OG5_126655
Brugia malayi loechrig isoform VII Get druggable targets OG5_128342 All targets in OG5_128342
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta Get druggable targets OG5_127587 All targets in OG5_127587
Schistosoma japonicum IPR002219,Protein kinase C, phorbol ester/diacylglycerol binding,domain-containing Get druggable targets OG5_131020 All targets in OG5_131020
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Schistosoma japonicum ko:K03115 casein kinase 2, beta polypeptide, putative Get druggable targets OG5_126846 All targets in OG5_126846
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative Get druggable targets OG5_126655 All targets in OG5_126655
Giardia lamblia Kinase, CAMK CAMKL Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126655 All targets in OG5_126655
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trypanosoma brucei mitogen-activated protein kinase kinase 5 Get druggable targets OG5_127304 All targets in OG5_127304
Echinococcus multilocularis rho associated protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania braziliensis casein kinase II, putative Get druggable targets OG5_126901 All targets in OG5_126901
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 12 357 aa 362 aa 30.1 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 13 365 aa 366 aa 30.1 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 14 360 aa 336 aa 33.3 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase-activated protein kinase 2 370 aa 303 aa 26.4 %
Brugia malayi CBS domain containing protein protein kinase, AMP-activated, gamma 1 non-catalytic subunit 340 aa 312 aa 23.7 %
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 270 aa 236 aa 47.5 %
Trypanosoma cruzi casein kinase II, alpha chain, putative casein kinase 2, alpha prime polypeptide 350 aa 319 aa 50.2 %
Trypanosoma cruzi casein kinase II, alpha chain, putative casein kinase 2, alpha 1 polypeptide 391 aa 316 aa 51.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Echinococcus multilocularis rac serine:threonine kinase 0.0138 0.1623 0.1623
Plasmodium falciparum casein kinase 2, alpha subunit 0.0173 0.2107 1
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0039 0.0253 0.0119
Brugia malayi intracellular kinase 0.0069 0.0674 0.0674
Brugia malayi ancient conserved domain protein 4 0.0025 0.0066 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0722 0.1746
Onchocerca volvulus 0.0126 0.1454 0.6312
Echinococcus granulosus tyrosine protein kinase Lyn 0.0032 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Echinococcus multilocularis casein kinase ii subunit beta 0.0044 0.0328 0.0328
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0025 0.0066 0.0066
Echinococcus granulosus tyrosine protein kinase csk 0.0041 0.028 0.028
Echinococcus granulosus mitogen activated protein kinase 14 0.0315 0.4065 0.4065
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.1356 0.1356
Echinococcus multilocularis acetylcholinesterase 0.0745 1 1
Brugia malayi ancient conserved domain protein 2 0.0025 0.0066 0.0066
Echinococcus multilocularis mitogen activated protein kinase 14 0.0315 0.4065 0.4065
Onchocerca volvulus 0.0187 0.2303 1
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.1361 0.438
Echinococcus granulosus protein kinase c iota type 0.0126 0.1457 0.1457
Toxoplasma gondii ck2 beta subunit 0.0044 0.0328 0.0871
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Echinococcus multilocularis nervana 2 0.0124 0.1426 0.1426
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0567 0.7552 0.7552
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0066 0.0629 0.1407
Entamoeba histolytica protein kinase, putative 0.0119 0.1361 0.438
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.1478 0.1478
Echinococcus multilocularis Glutaredoxin protein 5 0.0124 0.1426 0.1426
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.2303 0.2303
Echinococcus multilocularis serine:threonine protein kinase N2 0.0119 0.1356 0.1356
Echinococcus granulosus acetylcholinesterase 0.0745 1 1
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0124 0.1426 0.1426
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0044 0.0328 0.1414
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0126 0.1454 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0126 0.1454 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0126 0.1454 1
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0069 0.0674 0.0674
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0173 0.2107 1
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0039 0.0253 0.0119
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0328 0.1041
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0025 0.0066 0.5
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0136 0.1589 0.7461
Echinococcus granulosus acetylcholinesterase 0.0745 1 1
Brugia malayi Carboxylesterase family protein 0.0126 0.1454 0.1454
Trypanosoma brucei SNF1-related protein kinases, putative 0.0066 0.0629 0.1407
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0025 0.0066 0.0066
Echinococcus multilocularis protein kinase c iota type 0.0126 0.1457 0.1457
Brugia malayi chloride channel protein 7 0.0025 0.0066 0.0066
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0061 0.0559 0.0559
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0025 0.0066 0.0066
Onchocerca volvulus 0.0126 0.1454 0.6312
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.022 0.2751 0.2751
Giardia lamblia Kinase, STE STE20 0.0101 0.111 0.2954
Giardia lamblia Casein kinase II beta chain 0.0044 0.0328 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.1361 0.1361
Brugia malayi Protein kinase domain containing protein 0.0143 0.1695 0.1695
Echinococcus granulosus AMPK beta subunit 0.0137 0.1603 0.1603
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0298 0.3826 0.3826
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0298 0.3826 0.3826
Echinococcus granulosus cyclin dependent kinase 5 0.0063 0.0592 0.0592
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0069 0.0674 0.0674
Echinococcus multilocularis cyclin dependent kinase 5 0.0063 0.0592 0.0592
Echinococcus granulosus Protein kinase C brain isozyme 0.0175 0.2136 0.2136
Trypanosoma cruzi casein kinase II, putative 0.0173 0.2107 0.5104
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0229 0.2875 0.2875
Echinococcus multilocularis mitogen activated protein kinase 3 0.0073 0.0722 0.0722
Echinococcus granulosus casein kinase ii subunit alpha 0.0173 0.2107 0.2107
Trichomonas vaginalis CMGC family protein kinase 0.0069 0.0674 0.1578
Echinococcus multilocularis AMPK beta subunit 0.0137 0.1603 0.1603
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0137 0.1603 0.1603
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0136 0.1589 0.1589
Echinococcus granulosus serine:threonine kinase SAD 1 0.0066 0.0629 0.0629
Echinococcus multilocularis mitogen activated protein kinase 14 0.0315 0.4065 0.4065
Brugia malayi Protein kinase domain containing protein 0.0063 0.0592 0.0592
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0073 0.0722 0.0722
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Echinococcus granulosus serine/threonine protein kinase 0.0138 0.1623 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Echinococcus multilocularis neuroligin 0.0126 0.1454 0.1454
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Entamoeba histolytica protein kinase 2, putative 0.0136 0.1589 0.5118
Echinococcus granulosus rho-associated protein kinase 1 0.0187 0.2303 0.2303
Echinococcus granulosus casein kinase ii subunit beta 0.0044 0.0328 0.0328
Echinococcus multilocularis c src tyrosine kinase 0.0059 0.0528 0.0528
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0229 0.2875 0.2875
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0069 0.0674 0.0674
Echinococcus granulosus mitogen activated protein kinase 3 0.0073 0.0722 0.0722
Schistosoma mansoni serine/threonine kinase 0.0119 0.1356 0.1356
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0073 0.0722 0.164
Schistosoma mansoni BC026374 protein (S09 family) 0.0126 0.1454 0.1454
Plasmodium falciparum casein kinase II beta chain 0.0044 0.0328 0.128
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0315 0.4065 0.4065
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0025 0.0066 0.0066
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0025 0.0066 0.5
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0126 0.1454 0.1454
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0066
Schistosoma mansoni serine/threonine-protein kinase 0.0138 0.1623 0.1623
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0126 0.1454 0.1454
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0066
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0298 0.3826 0.3826
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0025 0.0066 0.0066
Echinococcus multilocularis protein kinase shaggy 0.0069 0.0674 0.0674
Echinococcus granulosus serine threonine protein kinase nrc 0.0136 0.1589 0.1589
Onchocerca volvulus 0.0126 0.1454 0.6312
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0143 0.1695 0.1695
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0629 0.0629
Trichomonas vaginalis STE family protein kinase 0.0101 0.111 0.3094
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0025 0.0066 0.5
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0069 0.0674 0.0674
Echinococcus granulosus protein kinase c epsilon type 0.0128 0.1478 0.1478
Brugia malayi CBS domain containing protein 0.0025 0.0066 0.0066
Echinococcus granulosus c src tyrosine kinase 0.0059 0.0528 0.0528
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Schistosoma mansoni protein kinase subunit beta 0.0073 0.0729 0.0729
Trichomonas vaginalis AGC family protein kinase 0.0119 0.1356 0.3948
Echinococcus multilocularis acetylcholinesterase 0.0745 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.1623 0.5229
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis STE family protein kinase 0.0101 0.111 0.3094
Schistosoma mansoni protein kinase 0.0101 0.111 0.111
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0066 0.0629 0.0629
Brugia malayi Protein kinase domain containing protein 0.0558 0.7417 0.7417
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0066 0.5
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0315 0.4065 1
Giardia lamblia Kinase, AGC PKA 0.0136 0.1589 0.4309
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0025 0.0066 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0143 0.1695 0.5125
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0137 0.1603 0.1603
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0315 0.4065 1
Echinococcus granulosus Glutaredoxin protein 5 0.0124 0.1426 0.1426
Brugia malayi Protein kinase c protein 2 0.0068 0.0659 0.0659
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0044 0.0328 0.0871
Chlamydia trachomatis CBS domain-containing protein 0.0025 0.0066 0.5
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0025 0.0066 0.5
Entamoeba histolytica hypothetical protein 0.0119 0.1361 0.438
Trichomonas vaginalis STE family protein kinase 0.0101 0.111 0.3094
Echinococcus multilocularis cyclin dependent kinase 1 0.0063 0.0592 0.0592
Trypanosoma brucei protein kinase, putative 0.0069 0.0674 0.1519
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0101 0.111 0.111
Loa Loa (eye worm) hypothetical protein 0.0054 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0055 0.0475 0.0475
Mycobacterium leprae Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) 0.0025 0.0066 0.5
Echinococcus granulosus BC026374 protein S09 family 0.0126 0.1454 0.1454
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0131 0.1532 0.4558
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0567 0.7552 0.7552
Echinococcus multilocularis casein kinase ii subunit alpha 0.0173 0.2107 0.2107
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0126 0.1454 0.1454
Onchocerca volvulus 0.0025 0.0066 0.0278
Schistosoma mansoni gliotactin 0.0126 0.1454 0.1454
Echinococcus granulosus NDR protein kinase 0.0119 0.1356 0.1356
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0044 0.0328 0.0653
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0069 0.0674 0.1519
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Schistosoma mansoni protein kinase 0.0173 0.2107 0.2107
Schistosoma mansoni chloride channel protein 0.0025 0.0066 0.0066
Loa Loa (eye worm) AGC/AKT protein kinase 0.0245 0.31 0.31
Brugia malayi Voltage gated chloride channel family protein 0.0025 0.0066 0.0066
Echinococcus multilocularis mitogen activated protein kinase 0.0073 0.0722 0.0722
Plasmodium falciparum casein kinase II beta chain 0.0044 0.0328 0.128
Brugia malayi Carboxylesterase family protein 0.0745 1 1
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0025 0.0066 0.0066
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0315 0.4065 1
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0119 0.1361 0.1361
Toxoplasma gondii histone kinase SNF1, putative 0.0066 0.0629 0.1875
Entamoeba histolytica protein kinase, putative 0.0069 0.0674 0.2159
Onchocerca volvulus 0.0126 0.1454 0.6312
Echinococcus granulosus neuroligin 0.0126 0.1454 0.1454
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0081 0.0829 0.2544
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0063 0.0592 0.0592
Brugia malayi Casein kinase II, alpha chain 0.0173 0.2107 0.2107
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0328 0.1041
Loa Loa (eye worm) Csnk2b protein 0.0044 0.0328 0.0328
Loa Loa (eye worm) AGC/PKN protein kinase 0.0119 0.1356 0.1356
Brugia malayi Csnk2b protein 0.0044 0.0328 0.0328
Brugia malayi map kinase activated protein kinase protein 2 0.0229 0.2875 0.2875
Echinococcus multilocularis carboxylesterase 5A 0.0745 1 1
Echinococcus multilocularis rho associated protein kinase 0.0187 0.2303 0.2303
Schistosoma mansoni acetylcholinesterase 0.0126 0.1454 0.1454
Brugia malayi Carboxylesterase family protein 0.0126 0.1454 0.1454
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0063 0.0592 0.0592
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0592 0.0592
Brugia malayi P38 map kinase family protein 2 0.0315 0.4065 0.4065
Plasmodium vivax glycogen synthase kinase 3, putative 0.0069 0.0674 0.1944
Brugia malayi cell division control protein 2 homolog 0.0063 0.0592 0.0592
Echinococcus multilocularis serine:threonine protein kinase 38 0.0119 0.1356 0.1356
Trypanosoma brucei rac serine-threonine kinase, putative 0.0245 0.31 0.7586
Treponema pallidum hemolysin (tlyC) 0.0025 0.0066 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0119 0.1361 0.3237
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.1623 0.5229
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0073 0.0722 0.164
Trypanosoma cruzi cdc2-related kinase 1 0.0063 0.0592 0.1314
Echinococcus multilocularis mitogen activated protein kinase 11 0.0315 0.4065 0.4065
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0137 0.1603 0.1603
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0044 0.0328 0.0653
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0063 0.0592 0.1314
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Treponema pallidum Mg2+ transport protein (mgtE) 0.0025 0.0066 0.5
Plasmodium falciparum glycogen synthase kinase 3 0.0069 0.0674 0.2975
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0073 0.0729 0.0729
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Leishmania major casein kinase II, putative 0.0173 0.2107 0.5104
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0722 0.1746
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.022 0.2751 0.2751
Loa Loa (eye worm) hypothetical protein 0.0054 0.0466 0.0466
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0256 0.325 0.325
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0722 0.0722
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Echinococcus multilocularis tyrosine protein kinase csk 0.0041 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0052 0.0429 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Entamoeba histolytica casein kinase, putative 0.0173 0.2107 0.6793
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0101 0.111 0.2611
Loa Loa (eye worm) hypothetical protein 0.0745 1 1
Brugia malayi Hr1 repeat family protein 0.0119 0.1356 0.1356
Schistosoma mansoni tyrosine kinase 0.0059 0.0528 0.0528
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0281 0.36 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0128 0.1478 0.1478
Trypanosoma brucei protein kinase, putative 0.0073 0.0722 0.164
Echinococcus granulosus dual specificity 0.0119 0.1361 0.1361
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.3826 0.3826
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Giardia lamblia Kinase, CMGC CK2 0.0173 0.2107 0.5776
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0173 0.2107 0.2107
Entamoeba histolytica protein kinase domain containing protein 0.0173 0.2107 0.6793
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Loa Loa (eye worm) carboxylesterase 0.0126 0.1454 0.1454
Brugia malayi CLC chloride channel protein 0.0025 0.0066 0.0066
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0073 0.0722 0.164
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0119 0.1356 0.1356
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Brugia malayi hypothetical protein 0.0126 0.1454 0.1454
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.2136 0.2136
Loa Loa (eye worm) carboxylesterase 0.0126 0.1454 0.1454
Echinococcus multilocularis RNA directed DNA polymerase 0.0048 0.0374 0.0374
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0073 0.0722 0.164
Loa Loa (eye worm) hypothetical protein 0.0048 0.0374 0.0374
Onchocerca volvulus 0.0069 0.0674 0.2918
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0025 0.0066 0.0066
Schistosoma mansoni atypical protein kinase C 0.0126 0.1457 0.1457
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0126 0.1454 0.1454
Loa Loa (eye worm) chloride channel 3 0.0025 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0025 0.0066 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.2875 0.2875
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0066 0.0629 0.1407
Plasmodium vivax protein kinase Crk2 0.0063 0.0592 0.1485
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0722 0.1746
Echinococcus granulosus mitogen activated protein kinase 0.0073 0.0722 0.0722
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0073 0.0722 0.164
Schistosoma mansoni neuroligin 3 (S09 family) 0.0126 0.1454 0.1454
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0066
Echinococcus granulosus nervana 2 0.0124 0.1426 0.1426
Giardia lamblia Kinase, CMGC CDK 0.0063 0.0592 0.1487
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0124 0.1426 0.1426
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0298 0.3826 0.3826
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Echinococcus granulosus mitogen activated protein kinase 11 0.0315 0.4065 0.4065
Loa Loa (eye worm) hypothetical protein 0.0119 0.1356 0.1356
Entamoeba histolytica cell division protein kinase 2, putative 0.0063 0.0592 0.1895
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Echinococcus multilocularis dual specificity mitogen activated protein 0.0101 0.111 0.111
Trichomonas vaginalis AGC family protein kinase 0.0146 0.173 0.5244
Brugia malayi putative serine/threonine kinase SADA gamma 0.0066 0.0629 0.0629
Echinococcus granulosus cyclin dependent kinase 1 0.0063 0.0592 0.0592
Mycobacterium ulcerans carboxylesterase, LipT 0.0126 0.1454 1
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Onchocerca volvulus Alicorn homolog 0.0119 0.1364 0.5919
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Plasmodium vivax unspecified product 0.0173 0.2107 1
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0722 0.1746
Entamoeba histolytica cell division protein kinase 2, putative 0.0063 0.0592 0.1895
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0281 0.36 0.36
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0069 0.0674 0.0674
Brugia malayi Carboxylesterase family protein 0.0126 0.1454 0.1454
Schistosoma mansoni serine/threonine protein kinase 0.0567 0.7552 0.7552
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0069 0.0674 0.2025
Trypanosoma brucei cdc2-related kinase 1 0.0063 0.0592 0.1314
Echinococcus multilocularis tyrosine protein kinase csk 0.0041 0.028 0.028
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0242 0.3065 0.3065
Echinococcus multilocularis serine threonine protein kinase 0.0168 0.2035 0.2035
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.2663 0.2663
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0101 0.111 0.2611
Loa Loa (eye worm) hypothetical protein 0.0066 0.0629 0.0629
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Loa Loa (eye worm) AGC/NDR protein kinase 0.0119 0.1356 0.1356
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Echinococcus granulosus carboxylesterase 5A 0.0745 1 1
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0119 0.1356 0.1356
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0281 0.36 0.36
Loa Loa (eye worm) acetylcholinesterase 1 0.0745 1 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0558 0.7417 0.7417
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0119 0.1356 0.1356
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0044 0.0328 0.0653
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0063 0.0592 0.1752
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0629 0.0629
Giardia lamblia Kinase, CMGC MAPK 0.0073 0.0722 0.1855
Brugia malayi p70 ribosomal S6 kinase beta 0.0242 0.3065 0.3065
Trichomonas vaginalis spcc417.12 protein, putative 0.0126 0.1454 0.4288
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0137 0.1603 0.3842
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Loa Loa (eye worm) IMP dehydrogenase 1 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0107 0.1197 0.1197
Echinococcus granulosus RNA directed DNA polymerase 0.0048 0.0374 0.0374
Giardia lamblia Kinase, CMGC CDK 0.0063 0.0592 0.1487
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Trypanosoma cruzi Protein kinase B 0.0138 0.1623 0.3894
Entamoeba histolytica protein kinase, putative 0.0119 0.1361 0.438
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0066
Brugia malayi SH2 domain containing protein 0.005 0.0406 0.0406
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0101 0.111 0.111
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0136 0.1589 0.1589
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0136 0.1589 0.3808
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0229 0.2875 0.2875
Echinococcus multilocularis serine:threonine protein kinase N2 0.0119 0.1356 0.1356
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Giardia lamblia Kinase, CAMK CAMKL 0.0066 0.0629 0.1592
Brugia malayi Protein kinase domain containing protein 0.0213 0.2663 0.2663
Echinococcus multilocularis cyclin dependent kinase 1 0.0063 0.0592 0.0592
Trichomonas vaginalis CMGC family protein kinase 0.0069 0.0674 0.1578
Loa Loa (eye worm) hypothetical protein 0.0107 0.1197 0.1197
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0592 0.1294
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0025 0.0066 0.0066
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0063 0.0592 0.0592
Plasmodium falciparum serine/threonine protein kinase KIN 0.0066 0.0629 0.2756
Schistosoma mansoni protein kinase subunit beta 0.0137 0.1603 0.1603
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0115 0.1309 0.3108
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0138 0.1623 0.3894
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0044 0.0328 0.1041
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0629 0.0629
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0137 0.1603 0.3842
Schistosoma mansoni protein kinase subunit gamma 0.0281 0.36 0.36
Trypanosoma cruzi cdc2-related kinase 1 0.0063 0.0592 0.1314
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0592 0.0592
Giardia lamblia Kinase, AGC AKT 0.0113 0.1275 0.342
Loa Loa (eye worm) loechrig isoform VII 0.0281 0.36 0.36
Onchocerca volvulus 0.0126 0.1454 0.6312
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0126 0.1454 0.1454
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0629 0.0629
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.1356 0.1356
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Brugia malayi MAP kinase sur-1 0.0073 0.0722 0.0722
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0025 0.0066 0.5
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0119 0.1361 0.3237
Echinococcus granulosus H:Cl exchange transporter 3 0.0025 0.0066 0.0066
Brugia malayi protein kinase C II. 0.0128 0.1478 0.1478
Echinococcus granulosus nervana 2 0.0124 0.1426 0.1426
Brugia malayi hypothetical protein 0.0054 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.022 0.2751 0.2751
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0044 0.0328 0.1414
Trichomonas vaginalis AGC family protein kinase 0.0245 0.31 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0063 0.0592 0.1314
Brugia malayi Stress-activated protein kinase jnk-1 0.0567 0.7552 0.7552
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0101 0.111 0.2611
Onchocerca volvulus 0.0175 0.2139 0.929
Echinococcus granulosus cyclin dependent kinase 0.0063 0.0592 0.0592
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0066 0.0629 0.1407
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0592 0.1294
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0044 0.0328 0.0653
Schistosoma mansoni chloride channel protein 0.0025 0.0066 0.0066
Trypanosoma cruzi cdc2-related kinase 3 0.0063 0.0592 0.1314
Echinococcus granulosus H:Cl exchange transporter 7 0.0025 0.0066 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Echinococcus granulosus tyrosine protein kinase csk 0.0041 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0745 1 1
Echinococcus multilocularis dual specificity 0.0119 0.1361 0.1361
Entamoeba histolytica protein kinase, putative 0.0242 0.3065 0.9889
Schistosoma mansoni chloride channel protein 0.0025 0.0066 0.0066
Toxoplasma gondii CMGC kinase, CK2 family 0.0173 0.2107 0.6805
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0119 0.1361 0.3237
Trichomonas vaginalis AGC family protein kinase 0.0143 0.1695 0.5125
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0137 0.1603 0.4348
Giardia lamblia Kinase, CMGC GSK 0.0069 0.0674 0.1718
Chlamydia trachomatis Mg++ transporter 0.0025 0.0066 0.5
Echinococcus multilocularis mitogen activated protein kinase 11 0.0315 0.4065 0.4065
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0025 0.0066 0.0066
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0136 0.1589 0.7088
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Entamoeba histolytica protein kinase, putative 0.0119 0.1356 0.4366
Echinococcus granulosus c-Jun N-terminal kinases 0.0567 0.7552 0.7552
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0066 0.0629 0.1692
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0213 0.2663 0.2663
Brugia malayi loechrig isoform VII 0.0281 0.36 0.36
Loa Loa (eye worm) chloride channel protein 7 0.0025 0.0066 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0066 0.0629 0.1407
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0048 0.0374 0.0374
Echinococcus multilocularis cyclin dependent kinase 0.0063 0.0592 0.0592
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0315 0.4065 1
Schistosoma mansoni casein kinase II beta subunit 0.0044 0.0328 0.0328
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0113 0.1275 0.1275
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0063 0.0592 0.0592
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0119 0.1356 0.1356
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0066 0.0629 0.1407
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0073 0.0722 0.164
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0073 0.0722 0.2186
Loa Loa (eye worm) hypothetical protein 0.0126 0.1454 0.1454
Entamoeba histolytica serine/threonine protein kinase, putative 0.0066 0.0629 0.2015
Brugia malayi Protein kinase domain containing protein 0.0119 0.1356 0.1356
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0066 0.0629 0.0629
Echinococcus granulosus para nitrobenzyl esterase 0.0126 0.1454 0.1454
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0126 0.1454 0.4288
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0745 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0592 0.1294
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0025 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0025 0.0066 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.0066 0.0629 0.1592
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0119 0.1361 0.3237
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0069 0.0674 0.1519
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Loa Loa (eye worm) TK/CSK protein kinase 0.0041 0.028 0.028
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Brugia malayi Carboxylesterase family protein 0.0126 0.1454 0.1454
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.0674 0.2159
Echinococcus multilocularis nervana 2 0.0124 0.1426 0.1426
Echinococcus multilocularis para nitrobenzyl esterase 0.0126 0.1454 0.1454
Trypanosoma cruzi cdc2-related kinase 3 0.0063 0.0592 0.1314
Plasmodium falciparum protein kinase 5 0.0063 0.0592 0.2574
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0119 0.1356 0.1356
Entamoeba histolytica protein kinase, putative 0.0245 0.31 1
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.022 0.2751 0.2751
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0175 0.2136 0.2136
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Loa Loa (eye worm) SH2 domain-containing protein 0.0047 0.0371 0.0371
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.1356 0.1356
Echinococcus granulosus dual specificity mitogen activated protein 0.0101 0.111 0.111
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.0674 0.2159
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0073 0.0729 0.0729
Trichomonas vaginalis casein kinase II beta chain, putative 0.0044 0.0328 0.0377
Entamoeba histolytica protein kinase, putative 0.0245 0.31 1
Loa Loa (eye worm) carboxylesterase 0.0745 1 1
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.2136 0.2136
Giardia lamblia Kinase, CMGC GSK 0.0069 0.0674 0.1718
Leishmania major hypothetical protein, conserved 0.0137 0.1603 0.3842
Echinococcus multilocularis tyrosine protein kinase csk 0.0041 0.028 0.028
Echinococcus granulosus H:Cl exchange transporter 4 0.0025 0.0066 0.0066
Echinococcus multilocularis BC026374 protein (S09 family) 0.0126 0.1454 0.1454
Echinococcus granulosus tyrosine protein kinase csk 0.0041 0.028 0.028
Toxoplasma gondii AGC kinase 0.0242 0.3065 1
Brugia malayi Protein kinase domain containing protein 0.0245 0.31 0.31
Onchocerca volvulus 0.005 0.0406 0.1753
Echinococcus granulosus protein kinase C gamma type 0.0168 0.2035 0.2035
Brugia malayi Protein kinase domain containing protein 0.0119 0.1361 0.1361
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0137 0.1603 0.3842
Trypanosoma brucei Casein kinase II 0.0173 0.2107 0.5104
Echinococcus granulosus serine:threonine protein kinase N2 0.0119 0.1356 0.1356
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0629 0.1422
Echinococcus multilocularis protein kinase c epsilon type 0.0128 0.1478 0.1478
Echinococcus multilocularis tyrosine protein kinase csk 0.0041 0.028 0.028
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0073 0.0722 0.164
Schistosoma mansoni serine/threonine-protein kinase 0.0138 0.1623 0.1623
Trypanosoma brucei cdc2-related kinase 3 0.0063 0.0592 0.1314
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.2107 0.6555
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0253 0.0119
Echinococcus granulosus protein kinase shaggy 0.0069 0.0674 0.0674

Activities

Activity type Activity value Assay description Source Reference
Hepatic Extraction ratio (ADMET) < 0.3 Hepatocyte microsomal extraction ratio in human ChEMBL. 16759861
IC50 (binding) = 2.5 nM Inhibition of p38alpha ChEMBL. 16759861
IC50 (binding) = 2.5 nM Inhibition of p38alpha ChEMBL. 16759861
IC50 (functional) = 24.5 nM Inhibition of LPS-induced TNFalpha production in human monocytes ChEMBL. 16759861
IC50 (functional) = 380 nM Inhibition of LPS-induced TNFalpha production in human whole blood ChEMBL. 16759861
IC50 (functional) = 380 nM Inhibition of LPS-induced TNFalpha production in human whole blood ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of phosphorylase kinase ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of DYRK1a ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PI3K ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CDK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CSK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of Lck ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CHK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of AMPK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of ROCK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of GSK3beta ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of P70S6K ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of SGK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PKBalpha ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PKC ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PKCalpha ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PRAK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MSK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MAPKAP-K2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MAPKAP-K1a ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of JNK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of ERK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MKK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of p38gamma ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of p38delta ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of DYRK1a ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CDK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CSK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of Lck ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of CHK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of AMPK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of ROCK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of GSK3beta ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of P70S6K ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of SGK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PKBalpha ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PKCalpha ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of PRAK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MSK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MAPKAP-K2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MAPKAP-K1a ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of JNK ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of ERK2 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of MKK1 ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of p38gamma ChEMBL. 16759861
IC50 (binding) > 10 uM Inhibition of p38delta ChEMBL. 16759861
Inhibition = 0 % Inhibition of hERG channel current in HEK293 cells at 3 uM ChEMBL. 16759861
Inhibition = 0 % Inhibition of hERG channel current in HEK293 cells at 3 uM ChEMBL. 16759861
Inhibition (functional) = 94 % Inhibition of LPS-induced TNFalpha release in rat at 3 mg/kg ChEMBL. 16759861
Solubility = 81 ug ml-1 Solubility in PBS buffer at ph 6.5 ChEMBL. 16759861

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 16759861

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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