Detailed information for compound 370569

Basic information

Technical information
  • TDR Targets ID: 370569
  • Name: N-[2-(3,3-dimethyl-2-oxoazetidin-1-yl)-5-(tri fluoromethyl)phenyl]-4-methyl-3-[2-(methylami no)quinazolin-6-yl]benzamide
  • MW: 533.544 | Formula: C29H26F3N5O2
  • H donors: 2 H acceptors: 4 LogP: 5.57 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNc1ncc2c(n1)ccc(c2)c1cc(ccc1C)C(=O)Nc1cc(ccc1N1CC(C1=O)(C)C)C(F)(F)F
  • InChi: 1S/C29H26F3N5O2/c1-16-5-6-18(12-21(16)17-7-9-22-19(11-17)14-34-27(33-4)36-22)25(38)35-23-13-20(29(30,31)32)8-10-24(23)37-15-28(2,3)26(37)39/h5-14H,15H2,1-4H3,(H,35,38)(H,33,34,36)
  • InChiKey: OJMWPSHLUJUPDD-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • N-[2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide
  • N-[2-(3,3-dimethyl-2-oxo-1-azetidinyl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)-6-quinazolinyl]benzamide
  • N-[2-(2-keto-3,3-dimethyl-azetidin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide
  • N-[2-(3,3-dimethyl-2-oxoazetidin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-(2-methylaminoquinazolin-6-yl)benzamide
  • N-[2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-(2-methylaminoquinazolin-6-yl)benzamide
  • N-[2-(3,3-dimethyl-2-oxo-1-azetidinyl)-5-(trifluoromethyl)phenyl]-4-methyl-3-(2-methylamino-6-quinazolinyl)benzamide
  • N-[2-(2-keto-3,3-dimethyl-azetidin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-(2-methylaminoquinazolin-6-yl)benzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References
Homo sapiens LCK proto-oncogene, Src family tyrosine kinase Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 14 Starlite/ChEMBL References
Homo sapiens Janus kinase 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Brugia malayi P38 map kinase family protein 2 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma congolense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Echinococcus granulosus mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania donovani mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Schistosoma japonicum ko:K04441 p38 MAP kinase, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania braziliensis mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase Get druggable targets OG5_128610 All targets in OG5_128610
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei gambiense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania mexicana mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania infantum mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 14 360 aa 336 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax heat shock protein, putative 0.0015 0.0043 0.0043
Brugia malayi Sex muscle abnormal protein 5 0.0009 0.0013 0.0013
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0282 0.1383 0.138
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0014 0.0038 0.0037
Schistosoma mansoni cell adhesion molecule 0.0015 0.0043 0.0043
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.0016 0.0076
Brugia malayi nuclear receptor NHR-67 0.0029 0.0115 0.0115
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0009 0.0015 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Giardia lamblia Hypothetical protein 0.0282 0.1383 0.138
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0007 0.0006 0.0005
Schistosoma mansoni titin 0.0007 0.0001 0.0001
Trichomonas vaginalis spliceosomal protein sap, putative 0.0031 0.0126 0.012
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0279 0.0279
Echinococcus multilocularis follistatin 0.0021 0.0076 0.0075
Echinococcus granulosus heat shock protein 0.0037 0.0152 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Schistosoma mansoni lamin 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0282 0.1383 0.1385
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0008 0.0003
Echinococcus multilocularis neuroglian 0.0014 0.0039 0.0038
Echinococcus multilocularis NCK adaptor protein 0.0009 0.0013 0.0012
Brugia malayi polk-prov protein 0.0035 0.0144 0.0144
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0007 0.0006 0.0033
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0008 0.0008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.005 0.0049
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0282 0.1383 0.1385
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0077 0.0071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Loa Loa (eye worm) cytochrome P450 0.0008 0.0008 0.0008
Echinococcus multilocularis cpg binding protein 0.0035 0.0143 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0008 0.0003
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.026 0.1273 0.1272
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0115 0.0114
Brugia malayi kinase, mitochondrial precursor 0.0007 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0279 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0279 0.0279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Echinococcus granulosus geminin 0.0386 0.1903 0.1902
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0279 0.0279
Schistosoma mansoni tyrosine kinase 0.0009 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Toxoplasma gondii exonuclease III APE 0.0022 0.0077 0.0516
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0015 0.0043 0.0307
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1997 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0027
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0282 0.1383 1
Brugia malayi Peroxidasin 0.0007 0.0001 0.0001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0094 0.0441 0.0442
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0176 0.0171
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0008 0.0008
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0282 0.1383 0.1378
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0008 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0441 0.0436
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0145 0.0694 0.0693
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0077 0.0077
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0008 0.0003
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.1997 0.9987 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0144 0.0144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0008 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.1383 0.138
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Brugia malayi CXXC zinc finger family protein 0.0033 0.0134 0.0134
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0279 0.0279
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0011 0.0025 0.0025
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0058 0.0058
Trichomonas vaginalis set domain proteins, putative 0.0273 0.1338 0.1335
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0008 0.0003
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0126 0.0126
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0279 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0082 0.0082
Plasmodium vivax DNA gyrase subunit B, putative 0.0007 0.0006 0.0005
Schistosoma mansoni immunophilin 0.1718 0.8585 0.8585
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Plasmodium vivax vivapain-2 0.0019 0.0065 0.0065
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0176 0.1236
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.026 0.1273 0.1268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0279 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0223 0.0218
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0007 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Echinococcus multilocularis agrin 0.0021 0.0076 0.0075
Leishmania major cytochrome p450-like protein 0.0008 0.0008 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0344 0.0339
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0076 0.0076
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.026 0.1273 0.1272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0279 0.0279
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.0152 0.0152
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0043 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0279 0.0279
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0279 0.0278
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.026 0.1273 0.9197
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0007 0.0006 0.0005
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0065 0.0064
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0279 0.0278
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0282 0.1383 0.1382
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0282 0.1383 0.138
Loa Loa (eye worm) SRC-1 0.0014 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0057
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0014 0.0038 0.0037
Echinococcus granulosus dna polymerase eta 0.0016 0.005 0.0049
Brugia malayi nuclear receptor RXR 0.0029 0.0115 0.0115
Mycobacterium leprae Probable lipase LipE 0.0041 0.0176 0.1236
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.2 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0065 0.0065
Brugia malayi splicing factor 3B subunit 3 0.0031 0.0126 0.0126
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0012 0.0027 0.0027
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0282 0.1383 0.1385
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0115 0.0822
Schistosoma mansoni endoplasmin 0.0037 0.0152 0.0152
Echinococcus multilocularis Immunoglobulin 0.0011 0.0025 0.0024
Plasmodium vivax heat shock protein 86, putative 0.0037 0.0152 0.0152
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0126 0.0901
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0018 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0065 0.0059
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0008 0.0003
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0007 0.0001 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0079 0.0078
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0007 0.0006 0.0001
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1997 0.9987 1
Schistosoma mansoni organic anion transporter 0.0031 0.0126 0.0126
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0076 0.0509
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0016 0.0011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0077 0.0517
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0132 0.0132
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0079 0.0079
Entamoeba histolytica cysteine proteinase 2 0.001 0.0018 0.0012
Echinococcus multilocularis 0.0008 0.0008 0.0007
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0082 0.0082
Toxoplasma gondii cathepsin CPL 0.0019 0.0065 0.0429
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0079 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Schistosoma mansoni protein phosphatase-2b 0.026 0.1273 0.1273
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0007 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.026 0.1273 0.1274
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0079 0.0079
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0329 0.1619 0.1615
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0018 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0011 0.0025 0.0024
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0007 0.0006 0.0001
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0031 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Schistosoma mansoni cell adhesion molecule 0.0007 0.0001 0.0001
Echinococcus granulosus NCK adaptor protein 0.0009 0.0013 0.0012
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Brugia malayi Immunoglobulin I-set domain containing protein 0.0008 0.0007 0.0007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Trypanosoma brucei unspecified product 0.0039 0.0163 0.0163
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0008 0.0019
Brugia malayi hypothetical protein 0.0011 0.0025 0.0024
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0076 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0008 0.002
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0018 0.0058 0.0052
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0014 0.0038 0.0038
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0079 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0144 0.0143
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0132 0.0131
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0007 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Onchocerca volvulus 0.0031 0.0124 0.0886
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0065
Plasmodium vivax endoplasmin, putative 0.0037 0.0152 0.0152
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0115 0.0115
Loa Loa (eye worm) agrin synaptic family protein 0.0021 0.0076 0.0076
Leishmania major DNA polymerase eta, putative 0.0016 0.005 0.0044
Echinococcus granulosus serine protein kinase ATM 0.0018 0.0058 0.0057
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0007 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0009 0.0015 0.0014
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.1997 0.9987 1
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0079 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.1383 0.138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0285 0.028
Trypanosoma cruzi MFS transporter, putative 0.0031 0.0126 0.0126
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0014 0.0038 0.0037
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0016 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0015 0.0015
Schistosoma mansoni cpg binding protein 0.0035 0.0143 0.0143
Schistosoma mansoni heat shock protein 0.0037 0.0152 0.0152
Onchocerca volvulus 0.0031 0.0126 0.0901
Plasmodium falciparum heat shock protein 90 0.0037 0.0152 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0008 0.002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0134 0.0134
Mycobacterium ulcerans lipase LipD 0.0041 0.0176 0.0171
Brugia malayi hypothetical protein 0.0022 0.0079 0.0079
Schistosoma mansoni nephrin 0.0007 0.0001 0.0001
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.1997 0.9987 1
Onchocerca volvulus 0.0019 0.0065 0.0461
Brugia malayi hypothetical protein 0.0022 0.0079 0.0079
Echinococcus multilocularis cysteine protease 0.0019 0.0065 0.0064
Schistosoma mansoni cytochrome P450 0.0008 0.0008 0.0008
Echinococcus multilocularis geminin 0.0386 0.1903 0.1902
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Schistosoma mansoni organic anion transporter 0.0031 0.0126 0.0126
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0115 0.0822
Mycobacterium tuberculosis Conserved protein 0.0041 0.0176 0.1237
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0013
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0007 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0008 0.0007 0.0006
Toxoplasma gondii Hsp90 domain-containing protein 0.0015 0.0043 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0015 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Echinococcus granulosus microtubule associated protein 2 0.0793 0.3948 0.3947
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0007 0.0001 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0176 0.0176
Onchocerca volvulus 0.0041 0.0176 0.1262
Trichomonas vaginalis DNA polymerase eta, putative 0.0046 0.02 0.0195
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0007 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0079 0.0079
Echinococcus granulosus cathepsin L 0.001 0.0018 0.0017
Mycobacterium ulcerans hypothetical protein 0.0041 0.0176 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0127 0.0127
Plasmodium falciparum cysteine proteinase falcipain 1 0.001 0.0018 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0124 0.0124
Trichomonas vaginalis fk506 binding protein, putative 0.0282 0.1383 0.138
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0008 0.0003
Brugia malayi FAT domain containing protein 0.0014 0.0037 0.0037
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0132 0.0131
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0279 0.0278
Onchocerca volvulus 0.0009 0.0015 0.0104
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.026 0.1273 0.1272
Schistosoma mansoni hypothetical protein 0.0145 0.0694 0.0694
Toxoplasma gondii target of rapamycin (TOR), putative 0.007 0.032 0.2281
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Plasmodium falciparum endoplasmin, putative 0.0022 0.0081 0.0075
Trypanosoma brucei unspecified product 0.0011 0.0025 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0007 0.0006 0.0006
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0029 0.0115 0.079
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1997 0.9987 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0016 0.0015
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0282 0.1383 1
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0279 0.0278
Echinococcus granulosus tyrosine protein kinase Lyn 0.0014 0.004 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0107 0.0107
Schistosoma mansoni hypothetical protein 0.0014 0.0037 0.0037
Mycobacterium ulcerans heat shock protein 90 0.0029 0.0115 0.0109
Schistosoma mansoni ferritin 0.001 0.0016 0.0016
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.1997 0.9987 0.9997
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0014 0.0038 0.0037
Schistosoma mansoni nephrin 0.0014 0.0039 0.0039
Echinococcus granulosus endoplasmin 0.0029 0.0115 0.0114
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0282 0.1383 0.138
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Schistosoma mansoni agrin 0.0021 0.0076 0.0076
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0079 0.0079
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0176 0.0176
Echinococcus granulosus cathepsin L cysteine protease 0.001 0.0018 0.0017
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0126 0.0901
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0115 0.0115
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0176 0.1237
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0014 0.0037 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0279 0.0279
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0132 0.0132
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0079 0.0079
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0079 0.0079
Echinococcus granulosus lamin 0.0031 0.0124 0.0123
Echinococcus multilocularis mitogen activated protein kinase 14 0.0152 0.0731 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0344 0.0339
Echinococcus granulosus roundabout 2 0.0018 0.0057 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0144 0.0144
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0007 0.0006 0.0001
Leishmania major cytochrome p450-like protein 0.0008 0.0008 0.0003
Echinococcus granulosus lamin dm0 0.0031 0.0124 0.0123
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0079 0.0079
Loa Loa (eye worm) heat shock protein 90 0.0037 0.0152 0.0152
Echinococcus granulosus neuroglian 0.0014 0.0039 0.0038
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Echinococcus granulosus dnaJ subfamily B 0.047 0.2327 0.2326
Echinococcus granulosus mitogen activated protein kinase 11 0.0152 0.0731 0.073
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0126 0.0901
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.2 1 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0009 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Mycobacterium leprae putative cytochrome p450 0.0008 0.0008 0.0019
Brugia malayi Probable DNA topoisomerase II 0.0007 0.0006 0.0005
Plasmodium vivax heat shock protein 90, putative 0.0015 0.0043 0.0043
Echinococcus multilocularis lamin 0.0031 0.0124 0.0123
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0079 0.0079
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0026 0.0026
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0329 0.1619 0.1621
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Echinococcus granulosus cysteine protease 0.001 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0033 0.0027
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0279 0.2007
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0031 0.0126 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0094 0.0441 0.0441
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0015 0.0043 0.0042
Schistosoma mansoni intermediate filament proteins 0.0031 0.0124 0.0124
Schistosoma mansoni endoplasmin 0.0037 0.0152 0.0152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Trichomonas vaginalis endoplasmin, putative 0.0022 0.0081 0.0075
Echinococcus multilocularis c src tyrosine kinase 0.0014 0.0038 0.0037
Trypanosoma cruzi DNA topoisomerase II, putative 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.005 0.005
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0115 0.0115
Mycobacterium ulcerans hypothetical protein 0.0329 0.1619 0.1617
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0008 0.002
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0029 0.0115 0.0791
Schistosoma mansoni tyrosine kinase 0.0014 0.0038 0.0038
Brugia malayi heat shock protein 90 0.0037 0.0152 0.0152
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0014 0.0037 0.0036
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0115 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0068 0.0452
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0279 0.0278
Loa Loa (eye worm) fibroinase 0.0019 0.0065 0.0065
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Echinococcus granulosus twitchin 0.0015 0.0042 0.0041
Brugia malayi SH2 domain containing protein 0.0009 0.0015 0.0015
Brugia malayi nuclear receptor NHR-88 0.0062 0.0279 0.0279
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0076 0.0509
Trypanosoma brucei heat shock protein 84, putative 0.0015 0.0043 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0336 0.0337
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0132 0.0132
Echinococcus granulosus heat shock protein 90 0.0037 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0121
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0115 0.0115
Schistosoma mansoni lamin 0.0031 0.0124 0.0124
Treponema pallidum bacterioferrin (TpF1) 0.001 0.0016 0.0011
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0107 0.0102
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0016 0.0077
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0077 0.0071
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Schistosoma mansoni nuclear receptor 0.0029 0.0115 0.0115
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0058 0.0058
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0186 0.0903 0.0904
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0132
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.026 0.1273 0.1274
Leishmania major cathepsin L-like protease 0.0019 0.0065 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0018 0.0018
Schistosoma mansoni ferritin 0.001 0.0016 0.0016
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0068 0.0068
Schistosoma mansoni ap endonuclease 0.0022 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Onchocerca volvulus 0.0031 0.0126 0.0901
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0008 0.0003
Trypanosoma cruzi target of rapamycin kinase 3 0.0075 0.0345 0.0345
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0132 0.0132
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Echinococcus multilocularis tyrosine protein kinase shark 0.0009 0.0015 0.0014
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0279 0.0279
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.026 0.1273 0.1268
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.02 0.0201
Echinococcus multilocularis ferritin 0.001 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0282 0.1383 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0176 0.0171
Schistosoma mansoni microtubule-associated protein tau 0.0793 0.3948 0.3948
Schistosoma mansoni adapter molecule crk 0.0009 0.0013 0.0013
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0079 0.0078
Onchocerca volvulus 0.0009 0.0015 0.0104
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0077 0.0071
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0014 0.0038 0.0037
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0007 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0027 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0441 0.0436
Leishmania major cathepsin L-like protease 0.0073 0.0336 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0065 0.0064
Echinococcus granulosus mitogen activated protein kinase 14 0.0152 0.0731 0.073
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.005 0.005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0008 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0176 0.1237
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.1997 0.9987 1
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Brugia malayi Cytochrome P450 family protein 0.0028 0.0107 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase Src64B 0.0014 0.0038 0.0037
Brugia malayi Tyrosine-protein kinase abl-1 0.0014 0.0038 0.0037
Loa Loa (eye worm) heat shock protein 75 0.0015 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Trichomonas vaginalis ferritin, putative 0.001 0.0016 0.0011
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0145 0.0694 0.0693
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0016 0.0015
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0008 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0224 0.0218
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0007 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0019 0.0065 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.026 0.1273 0.1274
Trichomonas vaginalis fk506-binding protein, putative 0.0282 0.1383 0.138
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.005 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.005 0.0323
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0018 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0144 0.0144
Schistosoma mansoni ferritin light chain 0.001 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0033
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.1295 0.9359
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0013 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0152 0.0731 0.0732
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0014 0.0038 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0027 0.0022
Echinococcus granulosus c src tyrosine kinase 0.0014 0.0038 0.0037
Echinococcus granulosus tyrosine protein kinase shark 0.0009 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Schistosoma mansoni ferritin 0.001 0.0016 0.0016
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0018 0.0058 0.0058
Schistosoma mansoni ferritin light chain 0.001 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0386 0.1903 0.1903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0058 0.0052
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0279 0.2007
Plasmodium vivax vivapain-3 0.001 0.0018 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Echinococcus multilocularis dna polymerase eta 0.0016 0.005 0.0049
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0386 0.1903 0.1903
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0279 0.0279
Schistosoma mansoni hypothetical protein 0.0282 0.1383 0.1383
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Echinococcus granulosus growth factor receptor bound protein 2 0.0009 0.0013 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Echinococcus multilocularis heat shock protein 0.0037 0.0152 0.0151
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0176 0.1237
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0127 0.0127
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0094 0.0441 0.0442
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0008 0.0003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0077 0.0516
Loa Loa (eye worm) hypothetical protein 0.003 0.0121 0.0121
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1997 0.9987 1
Entamoeba histolytica hypothetical protein 0.0018 0.0058 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0065 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0008 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0176 0.0176
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0279 0.0279
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0176 0.0171
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0068 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0079 0.0078
Mycobacterium tuberculosis Conserved protein 0.0007 0.0006 0.0001
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0127 0.0121
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.0016 0.0076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0018 0.0018
Echinococcus multilocularis heat shock protein 90 0.0037 0.0152 0.0151
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0152 0.0731 0.0732
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0018 0.0018
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.026 0.1273 0.1274
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0031 0.0126 0.012
Schistosoma mansoni growth factor receptor-bound protein 0.0009 0.0013 0.0013
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0029 0.0115 0.0114
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0115 0.0114
Treponema pallidum heat shock protein 90 0.0029 0.0115 0.0109
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0065 0.0065
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0043 0.0042
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0058 0.0058
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0008 0.0007 0.0006
Brugia malayi steroid hormone receptor 0.0062 0.0279 0.0279
Onchocerca volvulus 0.0283 0.1386 1
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0007 0.0006 0.0001
Echinococcus multilocularis tyrosine protein kinase Srms 0.0009 0.0015 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0033 0.0033
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.0152 0.0152
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0127 0.0127
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.02 0.0201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0058
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0065 0.0059
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0279 0.0278
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0065 0.0461
Echinococcus granulosus cathepsin l1 0.0013 0.0033 0.0032
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0016 0.0077
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0009 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0031 0.0126 0.0872
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0304 0.0305
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Brugia malayi Cathepsin L-like precursor 0.0013 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0007 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0279 0.0278
Toxoplasma gondii protease inhibitor PI2 0.0021 0.0076 0.0509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0018 0.0018
Plasmodium vivax vivapain-2 0.0019 0.0065 0.0065
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0007 0.0006 0.0001
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0279 0.0279
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0152 0.0146
Trypanosoma cruzi DNA topoisomerase II, putative 0.0007 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0115 0.0114
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0279 0.0279
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0223 0.0218
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0077 0.0071
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0058 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Plasmodium vivax unspecified product 0.001 0.0018 0.0018
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0008 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0144 0.0143
Onchocerca volvulus Tyrosine kinase homolog 0.0174 0.0843 0.6078
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0011 0.0025 0.0024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0007 0.0001 0.0001
Toxoplasma gondii FATC domain-containing protein 0.0018 0.0058 0.0378
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0115 0.0109
Entamoeba histolytica cysteine protease, putative 0.0019 0.0065 0.0059
Loa Loa (eye worm) TK protein kinase 0.0009 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Loa Loa (eye worm) TOPoisomerase family member 0.0007 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0031 0.0126 0.0126
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0079 0.0079
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0279 0.0278
Entamoeba histolytica protein kinase rad3, putative 0.0018 0.0058 0.0052
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.0152 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0279 0.0279
Brugia malayi protein-tyrosine kinase 0.0009 0.0015 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.02 0.0201
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0115 0.0115
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.2 1 1
Echinococcus granulosus expressed protein 0.0429 0.2121 0.212
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0107 0.0107
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0077 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0008 0.002
Onchocerca volvulus 0.0041 0.0176 0.1262
Echinococcus multilocularis 0.0329 0.1619 0.1618
Brugia malayi Prion-like- 0.0007 0.0001 0.0001
Echinococcus granulosus expressed protein 0.001 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0058 0.0261 0.0261
Echinococcus multilocularis heat shock protein 90 0.0029 0.0115 0.0114
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0029 0.0115 0.0109
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0077 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0115 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0279 0.0279
Trypanosoma cruzi heat shock protein 85, putative 0.0029 0.0115 0.0115
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0015 0.0043 0.0042
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0007 0.0006 0.0001
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0079 0.0078
Brugia malayi PXA domain containing protein 0.0022 0.0079 0.0079
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0094 0.0441 0.0442
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0176 0.0175
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0115 0.0115
Trichomonas vaginalis fk506-binding protein, putative 0.1997 0.9987 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Echinococcus granulosus cpg binding protein 0.0035 0.0143 0.0142
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0052 0.0051
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0065 0.0065
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Echinococcus granulosus splicing factor 3b subunit 3 0.0031 0.0126 0.0125
Brugia malayi beta-lactamase 0.0041 0.0176 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0251 0.0246
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0008 0.002
Schistosoma mansoni fk506 binding protein 0.0282 0.1383 0.1383
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0079 0.0079
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0007 0.0006 0.0001
Brugia malayi SH2 domain containing protein 0.0009 0.0015 0.0015
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0007 0.0006 0.0001
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0094 0.0441 0.0442
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0043 0.0038
Brugia malayi Cytochrome P450 family protein 0.0028 0.0107 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0008 0.002
Echinococcus granulosus Immunoglobulin 0.0011 0.0025 0.0024
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0279 0.0279
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0107 0.0107
Trichomonas vaginalis fk506-binding protein, putative 0.0282 0.1383 0.138
Mycobacterium ulcerans DNA polymerase IV 0.0046 0.02 0.0195
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0279 0.0279
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.0152 0.0147
Echinococcus multilocularis expressed protein 0.0429 0.2121 0.212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0279 0.0278
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0009 0.0015 0.0014
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0018 0.0058 0.0058
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0282 0.1383 0.138
Echinococcus multilocularis expressed protein 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0115 0.0109
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0124 0.0124
Echinococcus multilocularis Immunoglobulin 0.0011 0.0025 0.0024
Leishmania major hypothetical protein, conserved 0.0041 0.0176 0.0171
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0008 0.002
Onchocerca volvulus 0.0009 0.0015 0.0104
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0107 0.0107
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0163 0.0163
Brugia malayi beta-lactamase family protein 0.0041 0.0176 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0018 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0127 0.0127
Brugia malayi hypothetical protein 0.0009 0.0015 0.0015
Echinococcus multilocularis tyrosine protein kinase Abl 0.0014 0.0038 0.0037
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.026 0.1273 0.1268
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0008 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0008 0.002
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0008 0.002
Schistosoma mansoni vesicular amine transporter 0.0011 0.0025 0.0025
Entamoeba histolytica hypothetical protein 0.0022 0.0079 0.0073
Entamoeba histolytica hypothetical protein 0.0022 0.0079 0.0073
Loa Loa (eye worm) beta-lactamase 0.0041 0.0176 0.0176
Onchocerca volvulus 0.0031 0.0124 0.0886
Brugia malayi ecdysone receptor 0.0029 0.0115 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0007 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0279 0.0279
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0062 0.0062
Schistosoma mansoni nuclear receptor 0.0029 0.0115 0.0115
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0043 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0058 0.0052
Leishmania major DNA polymerase kappa, putative 0.0024 0.0087 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0223 0.0218
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0329 0.1619 0.1617
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Brugia malayi ecdysteroid receptor 0.0062 0.0279 0.0279
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0095 0.009
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0087 0.0594
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0279 0.0278
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0279 0.2007
Loa Loa (eye worm) TK/ROR protein kinase 0.0008 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0087 0.0087
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0082 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0152 0.0731 0.0732
Brugia malayi Protein kinase domain containing protein 0.0009 0.0015 0.0015
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1997 0.9987 1
Onchocerca volvulus 0.0033 0.0134 0.0959
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Trichomonas vaginalis esterase, putative 0.0041 0.0176 0.0171
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0033 0.0027
Trypanosoma cruzi heat shock protein, putative 0.0015 0.0043 0.0044
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0082 0.0082
Schistosoma mansoni pyruvate dehydrogenase 0.0007 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.026 0.1273 0.1268
Giardia lamblia DINP protein human, muc B family 0.0024 0.0087 0.0082
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.026 0.1273 0.1274
Leishmania major cathepsin L-like protease 0.0019 0.0065 0.0059
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0176 0.0176
Onchocerca volvulus 0.0013 0.0033 0.023
Echinococcus granulosus ferritin 0.001 0.0016 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0279 0.0278
Giardia lamblia Heat shock protein HSP 90-alpha 0.0029 0.0115 0.0109
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0115 0.0115
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0279 0.0278
Schistosoma mansoni immunophilin 0.2 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Trypanosoma brucei DNA polymerase IV, putative 0.0046 0.02 0.0201
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0077 0.0071
Brugia malayi P38 map kinase family protein 2 0.0152 0.0731 0.0732
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0079 0.0078
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.0192 0.0192
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.1716 0.8575 0.8586
Echinococcus granulosus tyrosine protein kinase Blk 0.0009 0.0015 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0018 0.0012
Brugia malayi nuclear receptor NHR-88 0.0029 0.0115 0.0115
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0077 0.0077
Brugia malayi hypothetical protein 0.0031 0.0126 0.0126
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0127 0.0126
Loa Loa (eye worm) FKBP5 protein 0.1997 0.9987 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Brugia malayi Cytochrome P450 family protein 0.0008 0.0008 0.0008
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0152 0.0152
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0282 0.1383 0.1384
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0079 0.0079
Onchocerca volvulus 0.0167 0.0804 0.5799
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0026 0.0025
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0018 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0132 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0058 0.0052
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.1172 0.1174
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0279 0.0279
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0152 0.0147
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0126 0.0872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0344 0.0339
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0075 0.0345 0.034
Schistosoma mansoni DNA topoisomerase II 0.0007 0.0006 0.0006
Brugia malayi prostaglandin transporter 0.0031 0.0126 0.0126
Echinococcus multilocularis expressed protein 0.001 0.0016 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0224 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0033 0.0027
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0008 0.0003
Mycobacterium tuberculosis Possible two component sensor kinase 0.0007 0.0006 0.0001
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0329 0.1619 0.1621
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0282 0.1383 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.1998 0.999 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0336 0.0337
Leishmania major cathepsin L-like protease 0.0073 0.0336 0.0331
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1997 0.9987 1
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0079 0.0078
Echinococcus multilocularis cysteine protease 0.0019 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0037
Schistosoma mansoni cpg binding protein 0.0033 0.0134 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Leishmania major peptidylprolyl isomerase-like protein 0.1997 0.9987 1
Brugia malayi SPARC precursor 0.0021 0.0076 0.0076
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0094 0.0441 0.0436
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0282 0.1383 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0126 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0008 0.002
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0094 0.0441 0.044
Giardia lamblia GTOR 0.0094 0.0441 0.0436
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0144 0.0143
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0014 0.0038 0.0037
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0282 0.1383 1
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0282 0.1383 0.138
Schistosoma mansoni follistatin 0.0021 0.0076 0.0076
Schistosoma mansoni cpg binding protein 0.0035 0.0143 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0251 0.0246
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0014 0.0038 0.0037
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0279 0.0279
Schistosoma mansoni heat shock protein 0.0015 0.0043 0.0043
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0115 0.0115
Brugia malayi nuclear hormone receptor 0.0062 0.0279 0.0279
Echinococcus granulosus heat shock protein 90 0.0029 0.0115 0.0114
Trypanosoma brucei protein phosphatase 2B, putative 0.026 0.1273 0.1274
Onchocerca volvulus 0.0029 0.0115 0.0822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0344 0.0339
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0224 0.0218
Onchocerca volvulus 0.0035 0.0144 0.1032
Brugia malayi Pre-SET motif family protein 0.024 0.1172 0.1173
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0008 0.002
Leishmania major fk506-binding protein 1-like protein 0.1997 0.9987 1
Brugia malayi conserved hypotetical protein 0.0029 0.0115 0.0115
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0065 0.0065
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Brugia malayi SRC-1 0.0014 0.0038 0.0037
Leishmania major cathepsin L-like protease 0.0019 0.0065 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0115 0.0115
Onchocerca volvulus 0.0019 0.0065 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0248 0.0243
Leishmania major cathepsin L-like protease 0.0073 0.0336 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0009 0.0015 0.001
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0079 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0077 0.0071
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0046 0.02 0.0195
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0152 0.0152
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0279 0.0279
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0018 0.0018
Echinococcus multilocularis lamin dm0 0.0031 0.0124 0.0123
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0079 0.0078
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0176 0.0171
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0065 0.0059
Brugia malayi nuclear hormone receptor 0.0029 0.0115 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0152 0.0146
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0282 0.1383 1
Echinococcus granulosus defective proboscis extension response 0.0011 0.0025 0.0024
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0008 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Onchocerca volvulus 0.0031 0.0126 0.0901
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.026 0.1273 0.1268
Entamoeba histolytica hypothetical protein 0.0022 0.0079 0.0073
Schistosoma mansoni immunophilin 0.2 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0144 0.0144
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0079 0.0078
Loa Loa (eye worm) DR-78 0.0029 0.0115 0.0115
Brugia malayi cytochrome P450 0.0008 0.0008 0.0008
Onchocerca volvulus 0.0031 0.0126 0.0901
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0282 0.1383 1
Echinococcus granulosus tyrosine kinase 0.0009 0.0015 0.0014
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0152 0.0152
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0014 0.0038 0.0037
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0115 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0008 0.002
Onchocerca volvulus 0.0019 0.0065 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0121
Echinococcus granulosus cathepsin l1 0.0019 0.0065 0.0064
Echinococcus granulosus tyrosine kinase 0.0009 0.0015 0.0014
Mycobacterium tuberculosis Probable two component sensor kinase 0.0007 0.0006 0.0001
Schistosoma mansoni nck2/grb4 0.0009 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.047 0.2327 0.2327
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0279 0.0279
Schistosoma mansoni tyrosine kinase 0.0009 0.0015 0.0015
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0031 0.0126 0.0125
Loa Loa (eye worm) TK protein kinase 0.0008 0.0007 0.0007
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0025 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0176 0.0176
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.026 0.1273 0.1268
Schistosoma mansoni DNA polymerase eta 0.0016 0.005 0.005
Brugia malayi hypothetical protein 0.0029 0.0115 0.0115
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0007 0.0006 0.0001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Echinococcus multilocularis splicing factor 3b subunit 3 0.0031 0.0126 0.0125
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0282 0.1383 0.1384
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0013 0.0013
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0176 0.0171
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0115 0.0115
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0033 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0115 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0279 0.0279
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0065 0.0461
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0076
Echinococcus multilocularis mitogen activated protein kinase 11 0.0152 0.0731 0.073
Brugia malayi nuclear receptor RXR 0.0033 0.0132 0.0132
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0014 0.0038 0.0037
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0076 0.0076
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0144
Echinococcus multilocularis roundabout 2 0.0018 0.0057 0.0056
Schistosoma mansoni septate junction protein 0.0007 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0288 0.2052
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.1997 0.9987 0.9987
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0094 0.0441 0.0441
Echinococcus multilocularis cathepsin L 0.001 0.0018 0.0017
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.026 0.1273 0.1269
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0015 0.0043 0.0038
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0013 0.0013
Brugia malayi Pre-SET motif family protein 0.0035 0.0144 0.0144
Loa Loa (eye worm) ctsf protein 0.0019 0.0065 0.0065
Entamoeba histolytica CPSF A subunit region protein, putative 0.0031 0.0126 0.012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0077 0.0077
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0075 0.0345 0.0345
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0076 0.0076
Schistosoma mansoni ferritin 0.001 0.0016 0.0016
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0082 0.0081
Echinococcus multilocularis dnaJ subfamily B 0.047 0.2327 0.2326
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Trypanosoma brucei heat shock protein, putative 0.0037 0.0152 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0279 0.0279
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0077 0.0077
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0058 0.0058
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0007 0.0006 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0082 0.0082
Echinococcus granulosus dna polymerase kappa 0.0046 0.02 0.0199
Echinococcus granulosus agrin 0.0021 0.0076 0.0075
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0176 0.0171
Loa Loa (eye worm) cysteine protease 0.0019 0.0065 0.0065
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0279 0.0279
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0052 0.0051
Onchocerca volvulus 0.0009 0.0015 0.0104
Brugia malayi Protein kinase domain containing protein 0.0009 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Brugia malayi tailless protein 0.0029 0.0115 0.0115
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0077 0.0071
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0127 0.0126
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0079 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0344 0.0339
Plasmodium vivax DNA topoisomerase II, putative 0.0007 0.0006 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0279 0.0279
Onchocerca volvulus 0.0019 0.0065 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0441 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0121
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0043 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0077 0.0077
Brugia malayi secreted modular calcium-binding protein 1 0.0021 0.0076 0.0076
Brugia malayi intermediate filament protein 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Leishmania major cathepsin L-like protease 0.0019 0.0065 0.0059
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0176 0.0176
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.026 0.1273 0.1269
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0932 0.4645 0.4644
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0007 0.0006 0.0005
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0008 0.0003
Leishmania major cytochrome p450-like protein 0.0028 0.0107 0.0102
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0087 0.0082
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0127 0.0127
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0081 0.0075
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0079 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0224 0.0218
Brugia malayi Endoplasmin precursor 0.0037 0.0152 0.0152
Echinococcus multilocularis fk506 binding protein 0.1997 0.9987 0.9987
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0115 0.0109
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.005 0.005
Brugia malayi Hsp90 protein 0.0015 0.0043 0.0043
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0176 0.1237
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0076 0.0076
Echinococcus granulosus FK506 binding protein 2 0.0329 0.1619 0.1618
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0079 0.0078
Mycobacterium ulcerans beta-lactamase 0.0041 0.0176 0.0171
Echinococcus multilocularis musashi 0.0031 0.0124 0.0123
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.1997 0.9987 1
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Loa Loa (eye worm) endoplasmin 0.0037 0.0152 0.0152
Trypanosoma brucei hypothetical protein, conserved 0.0282 0.1383 0.1385
Echinococcus granulosus follistatin 0.0021 0.0076 0.0075
Echinococcus multilocularis tyrosine kinase 0.0009 0.0015 0.0014
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0279 0.0279
Schistosoma mansoni apoferritin-2 0.001 0.0016 0.0016
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0176 0.0175
Onchocerca volvulus 0.0031 0.0126 0.0901
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0152 0.0152
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.1997 0.9987 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0126 0.0126
Brugia malayi hypothetical protein 0.0031 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0094 0.0441 0.044
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0115 0.0114
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0079 0.0079
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0077 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0065 0.0059
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0107 0.0107
Entamoeba histolytica deoxycytidyl transferase, putative 0.0016 0.005 0.0044
Echinococcus multilocularis mitogen activated protein kinase 11 0.0152 0.0731 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0248 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0007 0.0006 0.0033
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0107 0.0107
Trypanosoma brucei unspecified product 0.0011 0.0025 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0079 0.0079
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.1997 0.9987 1
Toxoplasma gondii heat shock protein HSP90 0.0037 0.0152 0.1062
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0115 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0186 0.0903 0.0904
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0076 0.0509
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0009 0.0015 0.0014
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.1997 0.9987 0.9987
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0065 0.0059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0132
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0124 0.0124
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0058 0.0057
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0132
Echinococcus granulosus intermediate filament protein 0.0031 0.0124 0.0123
Mycobacterium ulcerans DNA polymerase IV 0.0046 0.02 0.0195
Brugia malayi cathepsin L-like precursor 0.0013 0.0033 0.0033
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.138
Echinococcus multilocularis serine protein kinase ATM 0.0018 0.0058 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0079 0.0073
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.02 0.0201
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Onchocerca volvulus 0.0019 0.0065 0.0461
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0076 0.0509
Schistosoma mansoni thyroid hormone receptor 0.0207 0.1005 0.1005
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0115 0.0114
Schistosoma mansoni roundabout 0.0007 0.0001 0.0001
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0079 0.0079
Trypanosoma cruzi cysteine protease, putative 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0067 0.0067
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.1997 0.9987 1
Schistosoma mansoni cell adhesion molecule 0.0007 0.0001 0.0001
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0257 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0275 0.027
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.026 0.1273 0.1274
Brugia malayi Immunoglobulin I-set domain containing protein 0.0007 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0062 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0256 0.1254 0.1256
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.1718 0.8585 0.8585
Echinococcus multilocularis thyroid hormone receptor alpha 0.0207 0.1005 0.1004
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.1385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0336 0.0337
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0005
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0008 0.002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0014 0.0038 0.0037
Onchocerca volvulus 0.0021 0.0076 0.054
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0031 0.0183
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0009 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0279 0.0279
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.0152 0.1062
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0176 0.1237
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0326 0.0326
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0077 0.0076
Schistosoma mansoni heat shock protein 0.0037 0.0152 0.0152
Echinococcus multilocularis tyrosine protein kinase Blk 0.0009 0.0015 0.0014
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0008 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0279 0.0279
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0144 0.1005
Brugia malayi Cathepsin L-like precursor 0.0019 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0076
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0009 0.0015 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0132
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0115 0.0114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0038 0.0037
Onchocerca volvulus 0.0041 0.0176 0.1262
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0062 0.0279 0.0279
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0065 0.0059
Schistosoma mansoni zinc finger protein 0.0029 0.0115 0.0115
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0065 0.0064
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0285 0.1396 0.1396
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0144 0.0144
Brugia malayi Fibronectin type III domain containing protein 0.0011 0.0025 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0062 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0127 0.0127
Onchocerca volvulus 0.0031 0.0126 0.0901
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.005
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0079 0.0078
Schistosoma mansoni tyrosine kinase 0.0014 0.0038 0.0038
Plasmodium vivax SET domain protein, putative 0.0035 0.0144 0.0144
Brugia malayi Cathepsin L-like precursor 0.0013 0.0033 0.0033
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0079 0.0079
Echinococcus granulosus tyrosine protein kinase Srms 0.0009 0.0015 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0279 0.0278
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0279 0.0279
Brugia malayi Protein kinase domain containing protein 0.0009 0.0015 0.0015
Brugia malayi Cytochrome P450 family protein 0.0008 0.0008 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0279 0.0278
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.0165 0.0165
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0018 0.0018
Onchocerca volvulus 0.0282 0.1383 0.9977
Plasmodium vivax vivapain-1 0.001 0.0018 0.0018
Echinococcus multilocularis mitogen activated protein kinase 14 0.0152 0.0731 0.073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0065 0.0059
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0065 0.0059
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0126
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0094 0.0441 0.0436
Toxoplasma gondii ABC1 family protein 0.0041 0.0176 0.1236
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0282 0.1383 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0279 0.0279
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0094 0.0441 0.0436
Onchocerca volvulus 0.0062 0.0279 0.2007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0279 0.0279
Trichomonas vaginalis immunophilin, putative 0.1997 0.9987 1
Echinococcus granulosus Solute carrier organic anion transporter family 0.0031 0.0126 0.0125
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.005 0.005
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0079 0.0079
Brugia malayi beta-lactamase family protein 0.0041 0.0176 0.0176
Echinococcus multilocularis microtubule associated protein 2 0.0793 0.3948 0.3947
Loa Loa (eye worm) TK/ABL protein kinase 0.0009 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase ABL1 0.0009 0.0015 0.0014
Schistosoma mansoni ap endonuclease 0.0022 0.0077 0.0077
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1997 0.9987 1
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0007 0.0006 0.0006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0134 0.0133
Trypanosoma brucei DNA polymerase IV, putative 0.0046 0.02 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0008 0.002
Brugia malayi Protein kinase domain containing protein 0.0009 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0018 0.0018
Onchocerca volvulus 0.0009 0.0015 0.0104
Schistosoma mansoni neuroglian 0.0007 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0018 0.0012
Onchocerca volvulus 0.0009 0.0015 0.0104
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0065 0.0059
Trypanosoma brucei DNA polymerase eta, putative 0.0016 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0008 0.002
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0008 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0079 0.0078
Brugia malayi hypothetical protein 0.0029 0.0115 0.0115
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0152 0.0731 0.0732
Schistosoma mansoni cell adhesion molecule 0.0007 0.0001 0.0001
Trypanosoma cruzi heat shock protein 90, putative 0.0029 0.0115 0.0115
Onchocerca volvulus 0.0019 0.0065 0.0461
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0115
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0115 0.0114
Entamoeba histolytica cysteine protease, putative 0.001 0.0018 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0094 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0079
Mycobacterium tuberculosis Conserved protein 0.0041 0.0176 0.1237
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0015
Onchocerca volvulus 0.0019 0.0065 0.0461
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0062 0.0062
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.026 0.1273 0.1272
Schistosoma mansoni protein phosphatase-2b 0.026 0.1273 0.1273
Schistosoma mansoni tyrosine kinase 0.0014 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0329 0.1619 0.1621
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0176 0.0171
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0018 0.0012
Onchocerca volvulus 0.0273 0.1338 0.9651
Echinococcus multilocularis dna polymerase kappa 0.0046 0.02 0.0199
Onchocerca volvulus 0.0029 0.0115 0.0822
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0152 0.0731 0.0727
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0007 0.0006 0.0001
Brugia malayi PXA domain containing protein 0.0022 0.0079 0.0079
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.005 0.005
Mycobacterium tuberculosis Conserved protein 0.0041 0.0176 0.1237
Leishmania major heat shock protein 83-1 0.0037 0.0152 0.0147
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0279 0.0279
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0176 0.1237
Toxoplasma gondii heat shock protein 75, putative 0.0015 0.0043 0.0275
Schistosoma mansoni thyroid hormone receptor 0.0207 0.1005 0.1005
Trypanosoma brucei developmentally regulated phosphoprotein 0.0007 0.0006 0.0006
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0009 0.0013 0.0013
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0008 0.002
Schistosoma mansoni hypothetical protein 0.0008 0.0008 0.0008
Leishmania major heat shock protein, putative 0.0015 0.0043 0.0038
Schistosoma mansoni tyrosine kinase 0.0011 0.0025 0.0025
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0282 0.1383 0.138
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0031 0.0126 0.0126
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0094 0.0441 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.032 0.0315
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0007 0.0006 0.0033
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.02 0.0201
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0079 0.0073
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0079 0.0078
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0007 0.0006 0.0006
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0115 0.0115
Trypanosoma brucei DNA topoisomerase ii 0.0007 0.0006 0.0006
Giardia lamblia Grp94/Hsp90 0.0029 0.0115 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0251 0.0246
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0029 0.0115 0.079
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0329 0.1619 0.1621
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0176 0.1237
Loa Loa (eye worm) TK/FER protein kinase 0.0009 0.0015 0.0015
Leishmania major serine/threonine protein phosphatase, putative 0.026 0.1273 0.1269
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0015
Schistosoma mansoni apoferritin-2 0.001 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0009 0.0015 0.0014
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.1718 0.8585 0.8585
Echinococcus multilocularis endoplasmin 0.0029 0.0115 0.0114
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0065 0.0461
Schistosoma mansoni septate junction protein 0.0007 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0336 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0037 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0336 0.0337
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0082 0.0082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0279 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0372 0.0367
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0127 0.0121

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 2.31 uM Inhibition of anti CD3-induced IL2 production in human whole blood ChEMBL. 16970394
Activity (functional) = 2.31 uM Inhibition of anti CD3-induced IL2 production in human whole blood ChEMBL. 16970394
IC50 (binding) = 2 nM Inhibition of Lck by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 2 nM Inhibition of Lck by HTRF kinase assay ChEMBL. 16970394
IC50 (functional) = 17 nM Inhibition of human T cell proliferation by mixed lymphocyte reaction ChEMBL. 16970394
IC50 (functional) = 89 nM Inhibition of anti CD3/CD28-induced IL2 secretion in human T cells ChEMBL. 16970394
IC50 (binding) = 172 nM Inhibition of p38alpha by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 172 nM Inhibition of p38alpha by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 193 nM Inhibition of Jak3 by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 193 nM Inhibition of Jak3 by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 360 nM Inhibition of KDR by HTRF kinase assay ChEMBL. 16970394
IC50 (binding) = 360 nM Inhibition of KDR by HTRF kinase assay ChEMBL. 16970394

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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