Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0083 | 0 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0083 | 0 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0083 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0083 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0083 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0083 | 0 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0083 | 0 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0083 | 0 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0083 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0083 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0083 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0083 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0214 | 1 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0083 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0083 | 0 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0083 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0083 | 0 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0083 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0083 | 0 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0083 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0214 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0214 | 1 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0083 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0214 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0083 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0083 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0214 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0214 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.