TDR Targets

Basic information

Technical information

TDR Targets ID: 370878
Name: (3,4-dimethylphenyl)-[2-[2-(4-methoxyphenyl)e thyl]triazol-4-yl]methanone
MW: 335.4 | Formula: C20H21N3O2
H donors: 0 H acceptors: 3 LogP: 4.51 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)CCn1ncc(n1)C(=O)c1ccc(c(c1)C)C
InChi: 1S/C20H21N3O2/c1-14-4-7-17(12-15(14)2)20(24)19-13-21-23(22-19)11-10-16-5-8-18(25-3)9-6-16/h4-9,12-13H,10-11H2,1-3H3
InChiKey: GFAWLUIEPMDUPY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(3,4-dimethylphenyl)-[2-[2-(4-methoxyphenyl)ethyl]-4-triazolyl]methanone
(3,4-dimethylphenyl)-[2-[2-(4-methoxyphenyl)ethyl]-1,2,3-triazol-4-yl]methanone

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	potassium voltage-gated channel, shaker-related subfamily, member 5	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Echinococcus multilocularis	potassium voltage gated channel protein	Get druggable targets OG5_127659	All targets in OG5_127659
Schistosoma japonicum	Potassium voltage-gated channel subfamily A member 5, putative	Get druggable targets OG5_127659	All targets in OG5_127659
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_127659	All targets in OG5_127659
Schistosoma japonicum	ko:K04876 potassium voltage-gated channel, Shaker-related subfamily A, member, putative	Get druggable targets OG5_127659	All targets in OG5_127659
Echinococcus granulosus	potassium voltage gated channel protein	Get druggable targets OG5_127659	All targets in OG5_127659
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	Get druggable targets OG5_127659	All targets in OG5_127659
Schistosoma japonicum	Potassium voltage-gated channel protein Shaker, putative	Get druggable targets OG5_127659	All targets in OG5_127659
Echinococcus granulosus	potassium voltage gated channel subfamily A	Get druggable targets OG5_127659	All targets in OG5_127659
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_127659	All targets in OG5_127659
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127659	All targets in OG5_127659
Echinococcus multilocularis	potassium voltage gated channel subfamily A	Get druggable targets OG5_127659	All targets in OG5_127659

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Echinococcus multilocularis	voltage gated potassium channel	potassium voltage-gated channel, shaker-related subfamily, member 5	613 aa	521 aa	34.9 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0029	0.0017	0.007
Brugia malayi	hypothetical protein	0.1209	0.1671	0.1671
Brugia malayi	Carboxylesterase family protein	0.1209	0.1671	0.1671
Plasmodium falciparum	protoporphyrinogen oxidase	0.0049	0.0046	1
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.1209	0.1671	1
Schistosoma mansoni	gliotactin	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0695	0.0951	0.5575
Brugia malayi	Choline O-acetyltransferase	0.0192	0.0246	0.0246
Schistosoma mansoni	cathepsin D (A01 family)	0.002	0.0005	0.0005
Schistosoma mansoni	choline o-acyltransferase	0.0192	0.0246	0.0246
Loa Loa (eye worm)	hypothetical protein	0.7153	1	1
Echinococcus multilocularis	neuroligin	0.1209	0.1671	0.1671
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0049	0.0046	0.0264
Echinococcus multilocularis	potassium voltage gated channel protein	0.0107	0.0126	0.0126
Onchocerca volvulus		0.0049	0.0046	0.0241
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.1213	0.1677	0.1677
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.004	0.0034	0.0169
Echinococcus multilocularis	carnitine O palmitoyltransferase 1, liver	0.0029	0.0017	0.0017
Echinococcus granulosus	hypothetical protein	0.0701	0.096	0.096
Echinococcus multilocularis	acetylcholinesterase	0.7153	1	1
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Brugia malayi	Carboxylesterase family protein	0.1209	0.1671	0.1671
Onchocerca volvulus		0.0035	0.0026	0.0123
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0029	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0799	0.1096	0.1096
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Echinococcus multilocularis	carboxylesterase 5A	0.7153	1	1
Brugia malayi	hypothetical protein	0.002	0.0005	0.0005
Echinococcus granulosus	neuroligin	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Echinococcus granulosus	potassium voltage gated channel subfamily A	0.0107	0.0126	0.0126
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.1209	0.1671	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0026	0.0026
Trichomonas vaginalis	set domain proteins, putative	0.0277	0.0366	0.2164
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0026	0.0026
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.002	0.0005	0.0005
Mycobacterium leprae	PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO)	0.0049	0.0046	0.5
Echinococcus granulosus	para nitrobenzyl esterase	0.1209	0.1671	0.1671
Plasmodium vivax	SET domain protein, putative	0.0035	0.0026	0.5113
Brugia malayi	amine oxidase, flavin-containing family protein	0.0049	0.0046	0.0046
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0029	0.0017	0.0017
Schistosoma mansoni	memapsin-2 (A01 family)	0.0505	0.0685	0.0685
Schistosoma mansoni	voltage-gated potassium channel	0.0051	0.0049	0.0049
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.002	0.0005	0.0005
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0047	0.0043	0.0043
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Toxoplasma gondii	histone lysine-specific demethylase LSD1/BHC110/KDMA1A	0.0049	0.0046	1
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0035	0.0026	0.0026
Brugia malayi	Pre-SET motif family protein	0.0035	0.0026	0.0026
Schistosoma mansoni	voltage-gated potassium channel	0.0107	0.0126	0.0126
Schistosoma mansoni	amine oxidase	0.0049	0.0046	0.0046
Onchocerca volvulus		0.0029	0.0017	0.007
Schistosoma mansoni	amine oxidase	0.0049	0.0046	0.0046
Schistosoma mansoni	hypothetical protein	0.0061	0.0062	0.0062
Leishmania major	C-8 sterol isomerase-like protein	0.0799	0.1096	1
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.0799	0.1096	0.1096
Brugia malayi	hypothetical protein	0.002	0.0005	0.0005
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0042	0.0035	0.0035
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Echinococcus granulosus	histone lysine methyltransferase setb	0.0035	0.0026	0.0026
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	0.0107	0.0126	0.0126
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0049	0.0046	0.0046
Mycobacterium ulcerans	carboxylesterase, LipT	0.1209	0.1671	1
Echinococcus granulosus	acetylcholinesterase	0.7153	1	1
Onchocerca volvulus		0.1209	0.1671	1
Loa Loa (eye worm)	hypothetical protein	0.7153	1	1
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Leishmania major	UDP-galactopyranose mutase	0.0049	0.0046	0.0264
Echinococcus multilocularis	choline O acetyltransferase	0.0192	0.0246	0.0246
Echinococcus multilocularis	potassium voltage gated channel subfamily A	0.0102	0.012	0.012
Onchocerca volvulus		0.1209	0.1671	1
Onchocerca volvulus		0.0277	0.0366	0.2164
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Loa Loa (eye worm)	carboxylesterase	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0408	0.0549	0.0549
Brugia malayi	Pepsin A precursor	0.002	0.0005	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0026	0.0026
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0049	0.0046	0.0046
Loa Loa (eye worm)	carboxylesterase	0.7153	1	1
Onchocerca volvulus		0.0029	0.0017	0.007
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0047	0.0043	0.0043
Schistosoma mansoni	choline o-acyltransferase	0.0029	0.0017	0.0017
Onchocerca volvulus		0.1209	0.1671	1
Brugia malayi	Carboxylesterase family protein	0.1209	0.1671	0.1671
Entamoeba histolytica	hypothetical protein	0.0042	0.0035	0.5
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0695	0.0951	0.5575
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0126	0.0126
Mycobacterium tuberculosis	Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO)	0.0646	0.0883	0.5152
Schistosoma mansoni	voltage-gated potassium channel	0.0107	0.0126	0.0126
Onchocerca volvulus		0.1209	0.1671	1
Schistosoma mansoni	hypothetical protein	0.0042	0.0035	0.0035
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0047	0.0043	0.0043
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0035	0.0026	0.0026
Entamoeba histolytica	hypothetical protein	0.0042	0.0035	0.5
Loa Loa (eye worm)	acetylcholinesterase 1	0.7153	1	1
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.1209	0.1671	0.1671
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.7153	1	1
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Loa Loa (eye worm)	choline/Carnitine O-acyltransferase	0.0029	0.0017	0.0017
Schistosoma mansoni	transcription factor LCR-F1	0.0042	0.0035	0.0035
Echinococcus multilocularis	BC026374 protein (S09 family)	0.1209	0.1671	0.1671
Brugia malayi	hypothetical protein	0.0049	0.0046	0.0046
Echinococcus granulosus	potassium voltage gated channel protein	0.0107	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0049	0.0046	1
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.0799	0.1096	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0017	0.0017
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0244	0.0318	0.0318
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Loa Loa (eye worm)	aspartic protease BmAsp-1	0.002	0.0005	0.0005
Brugia malayi	Pre-SET motif family protein	0.0244	0.0318	0.0318
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Echinococcus granulosus	carboxylesterase 5A	0.7153	1	1
Entamoeba histolytica	hypothetical protein	0.0042	0.0035	0.5
Loa Loa (eye worm)	hypothetical protein	0.002	0.0005	0.0005
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.002	0.0005	0.0005
Echinococcus granulosus	carnitine O palmitoyltransferase 1 liver	0.0029	0.0017	0.0017
Schistosoma mansoni	acetylcholinesterase	0.1209	0.1671	0.1671
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.002	0.0005	0.0005
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Echinococcus granulosus	BC026374 protein S09 family	0.1209	0.1671	0.1671
Onchocerca volvulus		0.0029	0.0017	0.007
Loa Loa (eye worm)	aspartyl protease 6	0.002	0.0005	0.0005
Schistosoma mansoni	voltage-gated potassium channel	0.0051	0.0049	0.0049
Echinococcus multilocularis	acetylcholinesterase	0.7153	1	1
Loa Loa (eye worm)	choline O-acetyltransferase	0.0192	0.0246	0.0246
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0035	0.0026	0.5113
Brugia malayi	Carboxylesterase family protein	0.1209	0.1671	0.1671
Trypanosoma brucei	C-8 sterol isomerase, putative	0.0799	0.1096	1
Echinococcus granulosus	carnitine O palmitoyltransferase 2	0.0029	0.0017	0.0017
Schistosoma mansoni	BC026374 protein (S09 family)	0.1209	0.1671	0.1671
Schistosoma mansoni	neuroligin 3 (S09 family)	0.1209	0.1671	0.1671
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0049	0.0046	1
Brugia malayi	Choline/Carnitine o-acyltransferase family protein	0.0029	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0192	0.0246	0.0246
Onchocerca volvulus		0.1209	0.1671	1
Brugia malayi	Carboxylesterase family protein	0.7153	1	1
Loa Loa (eye worm)	carnitine O-palmitoyltransferase I isoform	0.0029	0.0017	0.0017
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0034	0.0024	0.0024
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0046	0.0046
Brugia malayi	SWIRM domain containing protein	0.0049	0.0046	0.0046
Plasmodium vivax	hypothetical protein, conserved	0.0049	0.0046	1
Loa Loa (eye worm)	hypothetical protein	0.002	0.0005	0.0005
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0049	0.0046	0.0046
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0049	0.0046	1
Entamoeba histolytica	hypothetical protein	0.0042	0.0035	0.5
Mycobacterium tuberculosis	Carboxylesterase LipT	0.1209	0.1671	1
Echinococcus multilocularis	carnitine O palmitoyltransferase 2	0.0029	0.0017	0.0017
Brugia malayi	aspartic protease BmAsp-2, identical	0.002	0.0005	0.0005
Loa Loa (eye worm)	carboxylesterase	0.1209	0.1671	0.1671
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.1209	0.1671	0.1671
Toxoplasma gondii	histone lysine-specific demethylase	0.0049	0.0046	1
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0047	0.0043	0.0043
Echinococcus granulosus	acetylcholinesterase	0.7153	1	1
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.1209	0.1671	0.1671
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1671	0.1671
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.1209	0.1671	1
Plasmodium vivax	hypothetical protein, conserved	0.0049	0.0046	1
Brugia malayi	Eukaryotic aspartyl protease family protein	0.002	0.0005	0.0005
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0049	0.0046	0.0046
Brugia malayi	hypothetical protein	0.0042	0.0035	0.0035
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0035	0.0026	0.0026
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0049	0.0046	0.0046
Echinococcus multilocularis		0.0049	0.0046	0.0046
Echinococcus multilocularis	para nitrobenzyl esterase	0.1209	0.1671	0.1671
Schistosoma mansoni	cathepsin D (A01 family)	0.002	0.0005	0.0005
Echinococcus granulosus	choline O acetyltransferase	0.0192	0.0246	0.0246
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0049	0.0046	0.5
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0049	0.0046	0.0046
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Trichomonas vaginalis	spcc417.12 protein, putative	0.1209	0.1671	1
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.002	0.0005	0.0005
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.004	0.0034	0.0169
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0042	0.0035	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0035	0.0035
Brugia malayi	Serotonin receptor	0.0472	0.0638	0.0638
Echinococcus multilocularis	conserved hypothetical protein	0.0689	0.0943	0.0943
Brugia malayi	Choline O-acetyltransferase	0.0192	0.0246	0.0246
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0049	0.0046	1
Brugia malayi	aspartic protease BmAsp-1, identical	0.002	0.0005	0.0005
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0049	0.0046	0.0264
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0026	0.0026

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	0	Effect on ventricular effective refractory period in pig at 30 mg/kg after 15 mins	ChEMBL.	16793267
Activity (functional)	= 12 %	Increase in atrial effective refractory period in pig at 30 mg/kg after 15 mins	ChEMBL.	16793267
Activity (functional)	= 90 %	Blockade of Kv1.5 channel expressed in LTK cells at 1 uM by patch clamp method	ChEMBL.	16793267
Activity (functional)	= 90 %	Blockade of Kv1.5 channel expressed in LTK cells at 1 uM by patch clamp method	ChEMBL.	16793267
Activity (binding)	= 10.1 uM	Inhibition of Kv1.3 channel	ChEMBL.	16793267
Activity (binding)	= 10.1 uM	Inhibition of Kv1.3 channel	ChEMBL.	16793267
Activity (binding)	= 26 uM	Inhibition of L type calcium channel	ChEMBL.	16793267
Activity (binding)	= 26 uM	Inhibition of L type calcium channel	ChEMBL.	16793267
Activity	> 50 uM	Inhibition of hERG	ChEMBL.	16793267
Activity	> 50 uM	Inhibition of hERG	ChEMBL.	16793267
IC50 (functional)	= 294 nM	Blockade of Kv1.5 channel expressed in LTK cells by patch clamp method	ChEMBL.	16793267
IC50 (functional)	= 294 nM	Blockade of Kv1.5 channel expressed in LTK cells by patch clamp method	ChEMBL.	16793267

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL212453
PubChem: 16007209

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 370878