Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.4299 | 0.7321 | 1 |
Brugia malayi | hypothetical protein | 0.0505 | 0.0843 | 0.0843 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0052 | 0.0612 |
Echinococcus multilocularis | dihydrofolate reductase | 0.5868 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.0049 | 0.0064 | 0.0064 |
Toxoplasma gondii | endonuclease IV APN | 0.0076 | 0.011 | 0.015 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.0332 | 0.0332 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.0017 | 0.0017 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0098 | 0.1166 |
Onchocerca volvulus | 0.1062 | 0.1794 | 1 | |
Onchocerca volvulus | Netrin receptor homolog | 0.0014 | 0.0005 | 0.0028 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.4299 | 0.7321 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.0017 | 0.0017 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0031 | 0.0031 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.4299 | 0.7321 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0267 | 0.0267 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.0081 | 0.0119 | 0.0163 |
Entamoeba histolytica | NAD synthetase, putative | 0.0081 | 0.0119 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0014 | 0.0005 | 0.0005 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.5868 | 1 | 1 |
Leishmania major | NAD synthase, putative | 0.0081 | 0.0119 | 0.0163 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0029 | 0.0029 |
Schistosoma mansoni | glutamine-dependent NAD(+) synthetase | 0.0081 | 0.0119 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0005 | 0.0005 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.00000055003 | 0.0000000000083698 |
Mycobacterium tuberculosis | Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) | 0.0081 | 0.0119 | 0.0114 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0015 | 0.0009 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0098 | 0.0098 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0014 | 0.0005 | 0.0005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0047 | 0.0553 |
Plasmodium vivax | glutamine-dependent NAD(+) synthetase, putative | 0.0081 | 0.0119 | 0.0163 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0014 | 0.0005 | 0.0007 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0005 | 0.0005 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0005 | 0.0005 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4299 | 0.7321 | 1 |
Echinococcus granulosus | death domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0073 | 0.0105 | 0.0105 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0002 | 0.0002 |
Echinococcus multilocularis | geminin | 0.0167 | 0.0267 | 0.0267 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0505 | 0.0843 | 1 |
Onchocerca volvulus | 0.0234 | 0.0381 | 0.2121 | |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.011 | 0.011 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.0082 | 0.0082 |
Brugia malayi | thymidylate synthase | 0.1062 | 0.1794 | 0.1794 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0031 | 0.0031 |
Plasmodium falciparum | glutamine-dependent NAD(+) synthetase, putative | 0.0081 | 0.0119 | 0.0163 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0098 | 0.0098 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0098 | 0.0098 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0059 | 0.0082 | 0.0082 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.00000055354 | 0.0000000035158 |
Schistosoma mansoni | GMP synthetase | 0.0032 | 0.0036 | 0.0036 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.0082 | 0.008 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0098 | 0.0098 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.4299 | 0.7321 | 1 |
Schistosoma mansoni | netrin receptor unc5 | 0.0014 | 0.0005 | 0.0005 |
Mycobacterium leprae | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) | 0.0076 | 0.011 | 0.0095 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0047 | 0.026 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0002 | 0.0002 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0005 | 0.0005 |
Chlamydia trachomatis | dihydrofolate reductase | 0.5868 | 1 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.5868 | 1 | 1 |
Schistosoma mansoni | dihydrofolate reductase | 0.5868 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.5868 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0047 | 0.0553 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0098 | 0.0098 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0031 | 0.0031 |
Echinococcus multilocularis | thymidylate synthase | 0.1062 | 0.1794 | 0.1794 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0031 | 0.0031 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Brugia malayi | Hypothetical 29.7 kDa protein C05D11.5 in chromosome III | 0.002 | 0.0015 | 0.0015 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0017 | 0.0199 |
Trichomonas vaginalis | hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.00000055354 | 0.0000000035158 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0059 | 0.0082 | 0.0112 |
Onchocerca volvulus | 0.003 | 0.0032 | 0.0181 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0014 | 0.0005 | 0.0005 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0005 | 0.0005 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0098 | 0.1166 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.038 | 0.451 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0014 | 0.0005 | 0.0007 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.1062 | 0.1794 | 0.1782 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0009 | 0.0009 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Echinococcus granulosus | geminin | 0.0167 | 0.0267 | 0.0267 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1062 | 0.1794 | 0.1794 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0017 | 0.0017 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0027 | 0.0325 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Mycobacterium ulcerans | thymidylate synthase | 0.1062 | 0.1794 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0005 | 0.0005 |
Leishmania major | oxidoreductase-like protein | 0.0015 | 0.0006 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | endonuclease IV | 0.0076 | 0.011 | 0.0109 |
Echinococcus granulosus | GMP synthase glutamine hydrolyzing | 0.0032 | 0.0036 | 0.0036 |
Trichomonas vaginalis | nh(3)-dependent NAD(+) synthetase, putative | 0.0081 | 0.0119 | 0.1415 |
Mycobacterium leprae | PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) | 0.0081 | 0.0119 | 0.0105 |
Leishmania major | GMP synthase, putative,glutamine amidotransferase, putative | 0.0032 | 0.0036 | 0.0049 |
Brugia malayi | SET domain containing protein | 0.0012 | 0.0002 | 0.0002 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000055002 | 0.0000065209 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0059 | 0.0082 | 0.0076 |
Mycobacterium ulcerans | sugar phosphate isomerases/epimerases | 0.002 | 0.0015 | 0.0013 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.0085 | 0.0085 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0505 | 0.0843 | 0.1152 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0002 | 0.0002 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Onchocerca volvulus | 0.0011 | 0.00000055354 | 0.000000019596 | |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.5868 | 1 | 1 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0011 | 0.00000055003 | 0.0000000000083698 |
Plasmodium falciparum | GMP synthase [glutamine-hydrolyzing] | 0.0032 | 0.0036 | 0.0049 |
Trypanosoma brucei | GMP synthase [glutamine-hydrolysing] | 0.0032 | 0.0036 | 0.0049 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.0017 | 0.0199 |
Plasmodium vivax | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0076 | 0.011 | 0.015 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Mycobacterium ulcerans | NAD synthetase | 0.0081 | 0.0119 | 0.0118 |
Brugia malayi | CHD4 protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.0082 | 0.008 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0098 | 0.0098 |
Toxoplasma gondii | bifunctional GMP synthase/glutamine amidotransferase protein | 0.0032 | 0.0036 | 0.0049 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.0017 | 0.0017 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0015 | 0.0006 | 0.0008 |
Echinococcus granulosus | thymidylate synthase | 0.1062 | 0.1794 | 0.1794 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0002 | 0.0002 |
Toxoplasma gondii | glutamine-dependent NAD(+) synthetase protein, putative | 0.0081 | 0.0119 | 0.0163 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0006 | 0.0004 |
Brugia malayi | follicle stimulating hormone receptor | 0.0234 | 0.038 | 0.038 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0015 | 0.0006 | 0.0004 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.0332 | 0.0332 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.4299 | 0.7321 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000055002 | 0.0000065209 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0011 | 0.00000055003 | 0.0000000000083698 |
Onchocerca volvulus | 0.0041 | 0.005 | 0.0281 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0015 | 0.0015 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.0012 | 0.0017 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0031 | 0.0031 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Brugia malayi | DNA-(Apurinic or apyrimidinic site) lyase | 0.0076 | 0.011 | 0.011 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0017 | 0.0009 | 0.0009 |
Plasmodium falciparum | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0076 | 0.011 | 0.015 |
Trypanosoma brucei | NAD+ synthase, putative | 0.0081 | 0.0119 | 0.0163 |
Leishmania major | pteridine reductase 1 | 0.0198 | 0.0319 | 0.0436 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.00000055002 | 0.0000065209 |
Mycobacterium ulcerans | GMP synthase | 0.0032 | 0.0036 | 0.0035 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0505 | 0.0843 | 0.0838 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0027 | 0.0325 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0011 | 0.00000055002 | 0.0000065209 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0052 | 0.0288 |
Echinococcus multilocularis | GMP synthase (glutamine hydrolyzing) | 0.0032 | 0.0036 | 0.0036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Treponema pallidum | NAD synthetase | 0.0081 | 0.0119 | 0.5 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0015 | 0.0006 | 0.0004 |
Trypanosoma cruzi | NAD+ synthase, putative | 0.0081 | 0.0119 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0032 | 0.0032 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0002 | 0.0002 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0015 | 0.0006 | 0.0008 |
Onchocerca volvulus | 0.0015 | 0.0006 | 0.0032 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0041 | 0.005 | 0.005 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 0.038 | 0.038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0005 | 0.0005 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.5868 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0015 | 0.0013 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) | 0.0076 | 0.011 | 0.0104 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.0267 | 0.0267 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.00000055003 | 0.0000000000061277 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0002 | 0.0002 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0036 | 0.0036 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0002 | 0.0002 |
Plasmodium vivax | GMP synthetase, putative | 0.0032 | 0.0036 | 0.0049 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0031 | 0.0043 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0031 | 0.0043 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0047 | 0.0047 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0052 | 0.0612 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0015 | 0.0006 | 0.0004 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.00000055003 | 0.000006521 |
Brugia malayi | GMP synthase | 0.0032 | 0.0036 | 0.0036 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | epimerase | 0.002 | 0.0015 | 0.0013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.00000055002 | 0.0000065209 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0098 | 0.0098 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.0082 | 0.0082 |
Brugia malayi | Dihydrofolate reductase | 0.5868 | 1 | 1 |
Giardia lamblia | NH3-dependent NAD+ synthetase | 0.0081 | 0.0119 | 0.5 |
Onchocerca volvulus | Putative hydroxypyruvate isomerase | 0.002 | 0.0015 | 0.0082 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0015 | 0.0006 | 0.0008 |
Trypanosoma brucei | pteridine reductase 1 | 0.0192 | 0.0309 | 0.0422 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0073 | 0.0105 | 0.0105 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.1062 | 0.1794 | 0.179 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0005 | 0.0005 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | thymidylate synthase | 0.1062 | 0.1794 | 0.1794 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.