IC50 (binding)
|
= 42 nM
|
Inhibition of Aurora-A
|
ChEMBL.
|
17157005
|
IC50 (binding)
|
= 42 nM
|
Inhibition of Aurora kinase A (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 42 nM
|
Inhibition of Aurora-A
|
ChEMBL.
|
17157005
|
IC50 (binding)
|
= 42 nM
|
Inhibition of Aurora kinase A (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 131 nM
|
Inhibition of Lck (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 131 nM
|
Inhibition of Lck (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 386 nM
|
Inhibition of Bmx (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 386 nM
|
Inhibition of Bmx (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 591 nM
|
Inhibition of IGF1R (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 591 nM
|
Inhibition of IGF1R (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 887 nM
|
Inhibition of Syk (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
= 887 nM
|
Inhibition of Syk (unknown origin)
|
ChEMBL.
|
18077363
|
IC50 (binding)
|
> 10000 nM
|
Inhibition of EGFR
|
ChEMBL.
|
17157005
|
IC50 (binding)
|
> 10000 nM
|
Inhibition of EGFR
|
ChEMBL.
|
17157005
|
IC50 (binding)
|
= 20 uM
|
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay
|
ChEMBL.
|
21632247
|
Residual Activity (binding)
|
= -5 %
|
Millipore: Percentage of residual kinase activity of NTRK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= -3 %
|
Millipore: Percentage of residual kinase activity of MAPK10 at 10uM relative to control. Control inhibitor: JAK Inhibitor I at 30.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 1 %
|
Millipore: Percentage of residual kinase activity of AURKB at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 1 %
|
Millipore: Percentage of residual kinase activity of INSRR at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 1 %
|
Millipore: Percentage of residual kinase activity of BMX at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 1 %
|
Millipore: Percentage of residual kinase activity of NTRK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 2 %
|
Millipore: Percentage of residual kinase activity of AURKB at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 2 %
|
Millipore: Percentage of residual kinase activity of CSF1R at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 3 %
|
Millipore: Percentage of residual kinase activity of MUSK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 3 %
|
Millipore: Percentage of residual kinase activity of FLT3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 4 %
|
Millipore: Percentage of residual kinase activity of LIMK1 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 5 %
|
Millipore: Percentage of residual kinase activity of TNK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 6 %
|
Millipore: Percentage of residual kinase activity of IGF1R at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 6 %
|
Millipore: Percentage of residual kinase activity of BTK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 6 %
|
Millipore: Percentage of residual kinase activity of LYN at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 6 %
|
Millipore: Percentage of residual kinase activity of FLT1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 6 %
|
Millipore: Percentage of residual kinase activity of FLT4 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 7 %
|
Millipore: Percentage of residual kinase activity of FYN at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 7 %
|
Millipore: Percentage of residual kinase activity of AURKA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 7 %
|
Millipore: Percentage of residual kinase activity of EPHB1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 8 %
|
Millipore: Percentage of residual kinase activity of FGFR1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 9 %
|
Millipore: Percentage of residual kinase activity of CLK3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 9 %
|
Millipore: Percentage of residual kinase activity of TEC at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 10 %
|
Millipore: Percentage of residual kinase activity of STK17A at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 10 %
|
Millipore: Percentage of residual kinase activity of EPHB4 at 10uM relative to control. Control inhibitor: PP2 at 30.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 10 %
|
Millipore: Percentage of residual kinase activity of PTK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 11 %
|
Millipore: Percentage of residual kinase activity of FRK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 12 %
|
Millipore: Percentage of residual kinase activity of INSR at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 12 %
|
Millipore: Percentage of residual kinase activity of CAMK2G at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 12 %
|
Millipore: Percentage of residual kinase activity of PTK2B at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 12 %
|
Millipore: Percentage of residual kinase activity of SRC at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 13 %
|
Millipore: Percentage of residual kinase activity of INSRR at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 14 %
|
Millipore: Percentage of residual kinase activity of CSF1R at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 15 %
|
Millipore: Percentage of residual kinase activity of TXK at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 16 %
|
Millipore: Percentage of residual kinase activity of BMX at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 18 %
|
Millipore: Percentage of residual kinase activity of NTRK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 19 %
|
Millipore: Percentage of residual kinase activity of LCK at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 19 %
|
Millipore: Percentage of residual kinase activity of EGFR at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 19 %
|
Millipore: Percentage of residual kinase activity of JAK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 19 %
|
Millipore: Percentage of residual kinase activity of CAMK2D at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 19 %
|
Millipore: Percentage of residual kinase activity of EPHA2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 22 %
|
Millipore: Percentage of residual kinase activity of INSR at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 22 %
|
Millipore: Percentage of residual kinase activity of EPHA1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 22 %
|
Millipore: Percentage of residual kinase activity of EPHA1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 23 %
|
Millipore: Percentage of residual kinase activity of JAK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 24 %
|
Millipore: Percentage of residual kinase activity of AURKA at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 25 %
|
Millipore: Percentage of residual kinase activity of KDR at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 25 %
|
Millipore: Percentage of residual kinase activity of TNK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 26 %
|
Millipore: Percentage of residual kinase activity of LIMK1 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 26 %
|
Millipore: Percentage of residual kinase activity of EPHB2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 26 %
|
Millipore: Percentage of residual kinase activity of NUAK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 26 %
|
Millipore: Percentage of residual kinase activity of BRSK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 27 %
|
Millipore: Percentage of residual kinase activity of BRSK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 27 %
|
Millipore: Percentage of residual kinase activity of RPS6KA3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 29 %
|
Millipore: Percentage of residual kinase activity of MAP3K9 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 29 %
|
Millipore: Percentage of residual kinase activity of JAK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 29 %
|
Millipore: Percentage of residual kinase activity of TAOK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 30 %
|
Millipore: Percentage of residual kinase activity of DDR2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 31 %
|
Millipore: Percentage of residual kinase activity of CAMK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 32 %
|
Millipore: Percentage of residual kinase activity of GCK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 200 mM NaCl, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 32 %
|
Millipore: Percentage of residual kinase activity of GSG2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 32 %
|
Millipore: Percentage of residual kinase activity of TBK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 33 %
|
Millipore: Percentage of residual kinase activity of NEK3 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 34 %
|
Millipore: Percentage of residual kinase activity of PAK4 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 36 %
|
Millipore: Percentage of residual kinase activity of RPS6KA1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 37 %
|
Millipore: Percentage of residual kinase activity of FGFR2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 38 %
|
Millipore: Percentage of residual kinase activity of CAMK2B at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 38 %
|
Millipore: Percentage of residual kinase activity of MST1R at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 39 %
|
Millipore: Percentage of residual kinase activity of NLK at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 39 %
|
Millipore: Percentage of residual kinase activity of CDK6 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 39 %
|
Millipore: Percentage of residual kinase activity of PAK3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 40 %
|
Millipore: Percentage of residual kinase activity of PTK6 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 40 %
|
Millipore: Percentage of residual kinase activity of BRSK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 41 %
|
Millipore: Percentage of residual kinase activity of LYN at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 41 %
|
Millipore: Percentage of residual kinase activity of NUAK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 42 %
|
Millipore: Percentage of residual kinase activity of LCK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 43 %
|
Millipore: Percentage of residual kinase activity of EPHA7 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 44 %
|
Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 44 %
|
Millipore: Percentage of residual kinase activity of STK10 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 44 %
|
Millipore: Percentage of residual kinase activity of IRAK4 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 44 %
|
Millipore: Percentage of residual kinase activity of NTRK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 45 %
|
Millipore: Percentage of residual kinase activity of FLT3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 45 %
|
Millipore: Percentage of residual kinase activity of RPS6KA3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 46 %
|
Millipore: Percentage of residual kinase activity of PTK6 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 46 %
|
Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 46 %
|
Millipore: Percentage of residual kinase activity of KIT at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 47 %
|
Millipore: Percentage of residual kinase activity of EPHA3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 47 %
|
Millipore: Percentage of residual kinase activity of FYN at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 47 %
|
Millipore: Percentage of residual kinase activity of PASK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 48 %
|
Millipore: Percentage of residual kinase activity of ALK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 48 %
|
Millipore: Percentage of residual kinase activity of CHEK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 49 %
|
Millipore: Percentage of residual kinase activity of DAPK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 50 %
|
Millipore: Percentage of residual kinase activity of MARK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 50 %
|
Millipore: Percentage of residual kinase activity of IRAK4 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 50 %
|
Millipore: Percentage of residual kinase activity of SIK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 50 %
|
Millipore: Percentage of residual kinase activity of WNK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of MAPK10 at 1uM relative to control. Control inhibitor: JAK Inhibitor I at 30.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of IGF1R at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of MAP2K6 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol, 0.1 mM Na3VO4, 1 mg/mL BSA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of PTK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of YES1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 51 %
|
Millipore: Percentage of residual kinase activity of PRKX at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 52 %
|
Millipore: Percentage of residual kinase activity of IKBKB at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 52 %
|
Millipore: Percentage of residual kinase activity of PAK6 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 53 %
|
Millipore: Percentage of residual kinase activity of BTK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 53 %
|
Millipore: Percentage of residual kinase activity of FRK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 54 %
|
Millipore: Percentage of residual kinase activity of CSNK1G3 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 54 %
|
Millipore: Percentage of residual kinase activity of MYLK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 55 %
|
Millipore: Percentage of residual kinase activity of MET at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 55 %
|
Millipore: Percentage of residual kinase activity of FLT4 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 55 %
|
Millipore: Percentage of residual kinase activity of PTK2B at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 56 %
|
Millipore: Percentage of residual kinase activity of ITK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 56 %
|
Millipore: Percentage of residual kinase activity of YES1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 56 %
|
Millipore: Percentage of residual kinase activity of SRC at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 56 %
|
Millipore: Percentage of residual kinase activity of TAOK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 57 %
|
Millipore: Percentage of residual kinase activity of LCK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 57 %
|
Millipore: Percentage of residual kinase activity of BLK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 58 %
|
Millipore: Percentage of residual kinase activity of PAK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 58 %
|
Millipore: Percentage of residual kinase activity of SIK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 59 %
|
Millipore: Percentage of residual kinase activity of MINK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 59 %
|
Millipore: Percentage of residual kinase activity of FER at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 59 %
|
Millipore: Percentage of residual kinase activity of FGR at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 59 %
|
Millipore: Percentage of residual kinase activity of FLT1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 59 %
|
Millipore: Percentage of residual kinase activity of MAPK14 at 10uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 60 %
|
Millipore: Percentage of residual kinase activity of DAPK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 60 %
|
Millipore: Percentage of residual kinase activity of STK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 60 %
|
Millipore: Percentage of residual kinase activity of TXK at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 61 %
|
Millipore: Percentage of residual kinase activity of MELK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 61 %
|
Millipore: Percentage of residual kinase activity of EGFR at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 61 %
|
Millipore: Percentage of residual kinase activity of MAPK8 at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ? -mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 62 %
|
Millipore: Percentage of residual kinase activity of AURKC at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 62 %
|
Millipore: Percentage of residual kinase activity of EPHB1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 62 %
|
Millipore: Percentage of residual kinase activity of CAMK4 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 40 mM HEPES pH 7.4, 5 mM CaCl2, 30 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 62 %
|
Millipore: Percentage of residual kinase activity of RPS6KA2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 62 %
|
Millipore: Percentage of residual kinase activity of RPS6KB1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 63 %
|
Millipore: Percentage of residual kinase activity of FGFR4 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 63 %
|
Millipore: Percentage of residual kinase activity of MELK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 64 %
|
Millipore: Percentage of residual kinase activity of TSSK1B at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 64 %
|
Millipore: Percentage of residual kinase activity of PIM1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 65 %
|
Millipore: Percentage of residual kinase activity of STK24 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 65 %
|
Millipore: Percentage of residual kinase activity of WNK3 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 65 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of STK10 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of MYLK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of CAMK2D at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of PRKCA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of PRKG1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 uM cGMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of SGK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of ULK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 66 %
|
Millipore: Percentage of residual kinase activity of PIM1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 67 %
|
Millipore: Percentage of residual kinase activity of EPHA8 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 67 %
|
Millipore: Percentage of residual kinase activity of GSK3A at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 67 %
|
Millipore: Percentage of residual kinase activity of FGR at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 67 %
|
Millipore: Percentage of residual kinase activity of AKT3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 67 %
|
Millipore: Percentage of residual kinase activity of TAOK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 200 mM NaCl, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 68 %
|
Millipore: Percentage of residual kinase activity of DAPK2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 68 %
|
Millipore: Percentage of residual kinase activity of FES at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 68 %
|
Millipore: Percentage of residual kinase activity of ABL1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 68 %
|
Millipore: Percentage of residual kinase activity of ROS1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 69 %
|
Millipore: Percentage of residual kinase activity of AURKC at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl, 0.1% v/v Triton-X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 69 %
|
Millipore: Percentage of residual kinase activity of ALK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 69 %
|
Millipore: Percentage of residual kinase activity of ACVR1B at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 69 %
|
Millipore: Percentage of residual kinase activity of FGFR1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 69 %
|
Millipore: Percentage of residual kinase activity of RIPK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of MERTK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of MKNK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of CSNK1G2 at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of TEK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of PDGFRB at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 70 %
|
Millipore: Percentage of residual kinase activity of TYRO3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 71 %
|
Millipore: Percentage of residual kinase activity of CLK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 71 %
|
Millipore: Percentage of residual kinase activity of GSG2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 71 %
|
Millipore: Percentage of residual kinase activity of RIPK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 71 %
|
Millipore: Percentage of residual kinase activity of MARK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 71 %
|
Millipore: Percentage of residual kinase activity of MTOR at 1uM relative to control. Control inhibitor: Rapamycin at 10.0uM. Buffer: 50 mM HEPES pH 7.5, 1 mM EGTA, 0.01% Tween 20, 10 uM FKBP12
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of CDK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of STK24 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of CSNK2A2 at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 20 mM HEPES pH 7.6, 0.15 M NaCl, 0.1 mM EDTA, 5 mM DTT, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of MERTK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of DMPK at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of CHEK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 72 %
|
Millipore: Percentage of residual kinase activity of TGFBR1 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 73 %
|
Millipore: Percentage of residual kinase activity of LCK at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 73 %
|
Millipore: Percentage of residual kinase activity of STK17A at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 73 %
|
Millipore: Percentage of residual kinase activity of PLK3 at 1uM relative to control. Control inhibitor: Wortmannin at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 73 %
|
Millipore: Percentage of residual kinase activity of PLK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 74 %
|
Millipore: Percentage of residual kinase activity of IKBKB at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 74 %
|
Millipore: Percentage of residual kinase activity of PLK1 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 20 mM DTT
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 74 %
|
Millipore: Percentage of residual kinase activity of RET at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 75 %
|
Millipore: Percentage of residual kinase activity of CSNK2A1 at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 20 mM HEPES pH 7.6, 0.15 M NaCl, 0.1 mM EDTA, 5 mM DTT, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 75 %
|
Millipore: Percentage of residual kinase activity of PRKACA at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 75 %
|
Millipore: Percentage of residual kinase activity of SYK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 75 %
|
Millipore: Percentage of residual kinase activity of PASK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 76 %
|
Millipore: Percentage of residual kinase activity of MAP2K6 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol, 0.1 mM Na3VO4, 1 mg/mL BSA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 76 %
|
Millipore: Percentage of residual kinase activity of CLK3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 76 %
|
Millipore: Percentage of residual kinase activity of CAMK2G at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 76 %
|
Millipore: Percentage of residual kinase activity of JAK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 76 %
|
Millipore: Percentage of residual kinase activity of ABL1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 77 %
|
Millipore: Percentage of residual kinase activity of MAP2K1 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 50 mM Tris pH 7.5, 0.2 mM EGTA, 0.1% ?-mercaptoethanol, 0.01% Brij-35
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 77 %
|
Millipore: Percentage of residual kinase activity of MKNK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 77 %
|
Millipore: Percentage of residual kinase activity of BLK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 77 %
|
Millipore: Percentage of residual kinase activity of CHEK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 77 %
|
Millipore: Percentage of residual kinase activity of PRKCI at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of HCK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of HCK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of CSNK1D at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of RPS6KA1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of PLK1 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 20 mM DTT
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of TSSK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of TEC at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of TBK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 78 %
|
Millipore: Percentage of residual kinase activity of SGK3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of DDR2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of AXL at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of MET at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of GSK3B at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of CDK9 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of EPHA2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of MAPK14 at 1uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of SYK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 79 %
|
Millipore: Percentage of residual kinase activity of MTOR at 1uM relative to control. Control inhibitor: PI-103 at 30.0uM. Buffer: 50 mM HEPES pH 7.5, 1 mM EGTA, 0.01% Tween 20
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of EPHA5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of NEK11 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of CSNK1G2 at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of PAK4 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of PRKCE at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 80 %
|
Millipore: Percentage of residual kinase activity of PHKG2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of KDR at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of EPHA7 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of AXL at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of IRAK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of PRKAA1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 200 uM AMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of CHEK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 81 %
|
Millipore: Percentage of residual kinase activity of RET at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of CSNK1D at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of DCLK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of CLK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of IRAK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of MAP3K9 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 82 %
|
Millipore: Percentage of residual kinase activity of PRKCQ at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 83 %
|
Millipore: Percentage of residual kinase activity of PRKAA2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 200 uM AMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 83 %
|
Millipore: Percentage of residual kinase activity of FGFR3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 83 %
|
Millipore: Percentage of residual kinase activity of MTOR at 10uM relative to control. Control inhibitor: PI-103 at 30.0uM. Buffer: 50 mM HEPES pH 7.5, 1 mM EGTA, 0.01% Tween 20
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 83 %
|
Millipore: Percentage of residual kinase activity of RPS6KB1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of FES at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of MAPK1 at 10uM relative to control. Control inhibitor: ERK Inhibitor II at 30.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of CAMK4 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 40 mM HEPES pH 7.4, 5 mM CaCl2, 30 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of PRKCH at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of PRKCI at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of DAPK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of SGK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 84 %
|
Millipore: Percentage of residual kinase activity of MTOR at 10uM relative to control. Control inhibitor: Rapamycin at 10.0uM. Buffer: 50 mM HEPES pH 7.5, 1 mM EGTA, 0.01% Tween 20, 10 uM FKBP12
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 85 %
|
Millipore: Percentage of residual kinase activity of MAP2K7 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 85 %
|
Millipore: Percentage of residual kinase activity of AKT2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 85 %
|
Millipore: Percentage of residual kinase activity of RAF1 at 10uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 85 %
|
Millipore: Percentage of residual kinase activity of VRK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 86 %
|
Millipore: Percentage of residual kinase activity of INSR at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 86 %
|
Millipore: Percentage of residual kinase activity of CDK7 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 86 %
|
Millipore: Percentage of residual kinase activity of CAMK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 86 %
|
Millipore: Percentage of residual kinase activity of TSSK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 87 %
|
Millipore: Percentage of residual kinase activity of MINK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 87 %
|
Millipore: Percentage of residual kinase activity of MAP2K7 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol, 0.1 mM Na3VO4
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 87 %
|
Millipore: Percentage of residual kinase activity of SRPK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of CHUK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of GRK7 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of MUSK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of PRKAA2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 200 uM AMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of CDC42BPB at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of NEK3 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of PLK3 at 10uM relative to control. Control inhibitor: Wortmannin at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of MAPK11 at 10uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of ROCK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of ULK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 88 %
|
Millipore: Percentage of residual kinase activity of PDGFRA at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of SRPK3 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of STK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of CDK9 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of MAPK3 at 1uM relative to control. Control inhibitor: ERK Inhibitor II at 30.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of HIPK2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of MAPK1 at 1uM relative to control. Control inhibitor: ERK Inhibitor II at 30.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of MAP3K5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of RPS6KA5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of RPS6KA4 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of RPS6KA4 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of TYRO3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of AKT3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of STK33 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of RAF1 at 1uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 89 %
|
Millipore: Percentage of residual kinase activity of SGK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of IGF1R at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of NEK11 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of MAP3K5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of WNK3 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of SRPK2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of PRKG1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 uM cGMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of PAK6 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 90 %
|
Millipore: Percentage of residual kinase activity of PRKCG at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 91 %
|
Millipore: Percentage of residual kinase activity of FGFR3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 91 %
|
Millipore: Percentage of residual kinase activity of MAPK3 at 10uM relative to control. Control inhibitor: ERK Inhibitor II at 30.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 91 %
|
Millipore: Percentage of residual kinase activity of MARK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 92 %
|
Millipore: Percentage of residual kinase activity of EPHA4 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 92 %
|
Millipore: Percentage of residual kinase activity of STK4 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 92 %
|
Millipore: Percentage of residual kinase activity of CDK7 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 92 %
|
Millipore: Percentage of residual kinase activity of TAOK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of MARK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of DAPK2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of EPHB2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of HIPK2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of BRSK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of CSNK1G1 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of CSNK1G3 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of MAPK9 at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of TLK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of EEF2K at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of MST1R at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of VRK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore: Percentage of residual kinase activity of PDPK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 93 %
|
Millipore
|
LITERATURE.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of CDK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of GRK5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of GRK6 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of STK11 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.1% v/v Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of GSK3A at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of NEK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of CSNK1G1 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of TSSK1B at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of KIT at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore: Percentage of residual kinase activity of PHKG2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 94 %
|
Millipore
|
LITERATURE.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of NLK at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of DYRK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of EPHA3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of PRKCA at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of MAPK12 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of TAOK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of MAPK13 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 95 %
|
Millipore: Percentage of residual kinase activity of PRKCE at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of PRKAA1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 200 uM AMP
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of DYRK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of HIPK1 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of ITK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of ERBB4 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of CDK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of IGF1R at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of SRPK2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of PRKD2 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of RPS6KA6 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 96 %
|
Millipore: Percentage of residual kinase activity of PKN2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of CDK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of GCK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 200 mM NaCl, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of EPHA8 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of INSR at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of AKT2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of PAK7 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 97 %
|
Millipore: Percentage of residual kinase activity of ULK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of DAPK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of CDK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of CDK5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of ERBB4 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of MAPK12 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of PRKCG at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore: Percentage of residual kinase activity of PRKCZ at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 98 %
|
Millipore
|
LITERATURE.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of EPHA5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of GRK6 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of FGFR2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 2.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of PRKD2 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of PRKCB at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of MAP3K7 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 99 %
|
Millipore: Percentage of residual kinase activity of PDGFRB at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of STK11 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.1% v/v Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of CSK at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of CAMK2B at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of PRKCD at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 100 %
|
Millipore: Percentage of residual kinase activity of PDPK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 101 %
|
Millipore: Percentage of residual kinase activity of NEK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 101 %
|
Millipore: Percentage of residual kinase activity of PRKD1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 101 %
|
Millipore: Percentage of residual kinase activity of ULK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 101 %
|
Millipore: Percentage of residual kinase activity of EEF2K at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of GRK5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of PAK3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of DCLK2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of CDK6 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of HIPK1 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of CDK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of MAPK9 at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of EPHA4 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of PRKCQ at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of STK33 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of PLK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of PRKCB at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 102 %
|
Millipore: Percentage of residual kinase activity of ROS1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of NEK7 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of CDC42BPB at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of HIPK3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of HIPK3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of AKT1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of PRKX at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 103 %
|
Millipore: Percentage of residual kinase activity of MAPK11 at 1uM relative to control. Control inhibitor: SB203580 at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of NEK7 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of GRK7 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of GSK3B at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of PIM3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of PIM3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of AKT1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of TAOK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 200 mM NaCl, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 104 %
|
Millipore: Percentage of residual kinase activity of WNK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 105 %
|
Millipore: Percentage of residual kinase activity of SRPK3 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 105 %
|
Millipore: Percentage of residual kinase activity of NEK6 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 105 %
|
Millipore: Percentage of residual kinase activity of MAP3K7 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 105 %
|
Millipore: Percentage of residual kinase activity of TGFBR1 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of CAMK1D at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of MAP2K1 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 50 mM Tris pH 7.5, 0.2 mM EGTA, 0.1% ?-mercaptoethanol, 0.01% Brij-35
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of ACVR1B at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of EPHB3 at 1uM relative to control. Control inhibitor: PP2 at 30.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of PRKACA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of RPS6KA2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of ROCK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of PKN2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 106 %
|
Millipore: Percentage of residual kinase activity of PRKCD at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of CDK5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of NEK6 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK3 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of SRPK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of PAK7 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of MAPK13 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 25 mM Tris pH 7.5, 0.02 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of PDGFRA at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 107 %
|
Millipore: Percentage of residual kinase activity of PRKCH at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 108 %
|
Millipore: Percentage of residual kinase activity of FGFR4 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 108 %
|
Millipore: Percentage of residual kinase activity of CSNK2A2 at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 20 mM HEPES pH 7.6, 0.15 M NaCl, 0.1 mM EDTA, 5 mM DTT, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 108 %
|
Millipore: Percentage of residual kinase activity of ROCK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 108 %
|
Millipore: Percentage of residual kinase activity of SGK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 109 %
|
Millipore: Percentage of residual kinase activity of CSNK2A1 at 10uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 20 mM HEPES pH 7.6, 0.15 M NaCl, 0.1 mM EDTA, 5 mM DTT, 0.1% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 109 %
|
Millipore: Percentage of residual kinase activity of EPHB4 at 1uM relative to control. Control inhibitor: PP2 at 30.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 109 %
|
Millipore: Percentage of residual kinase activity of MAPK8 at 1uM relative to control. Control inhibitor: Jnk Inhibitor II at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% ? -mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 109 %
|
Millipore: Percentage of residual kinase activity of TLK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 110 %
|
Millipore: Percentage of residual kinase activity of STK4 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 110 %
|
Millipore: Percentage of residual kinase activity of PIM2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 113 %
|
Millipore: Percentage of residual kinase activity of EPHB3 at 10uM relative to control. Control inhibitor: PP2 at 30.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 113 %
|
Millipore: Percentage of residual kinase activity of CHUK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 113 %
|
Millipore: Percentage of residual kinase activity of ZAP70 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 114 %
|
Millipore: Percentage of residual kinase activity of RPS6KA5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 114 %
|
Millipore: Percentage of residual kinase activity of CAMK1D at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM CaCl2, 16 ug/mL calmodulin
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 115 %
|
Millipore: Percentage of residual kinase activity of CSK at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol, 10 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 115 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 116 %
|
Millipore: Percentage of residual kinase activity of PAK2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 116 %
|
Millipore: Percentage of residual kinase activity of ZAP70 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 116 %
|
Millipore: Percentage of residual kinase activity of PRKCZ at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 117 %
|
Millipore: Percentage of residual kinase activity of CDC42BPA at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 119 %
|
Millipore: Percentage of residual kinase activity of PIM2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 122 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK3 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 124 %
|
Millipore: Percentage of residual kinase activity of FER at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM MnCl2
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 125 %
|
Millipore: Percentage of residual kinase activity of DMPK at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 125 %
|
Millipore: Percentage of residual kinase activity of PRKD1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM HEPES pH 7.4, 0.03% Triton X-100
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 126 %
|
Millipore: Percentage of residual kinase activity of SGK3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 127 %
|
Millipore: Percentage of residual kinase activity of ROCK1 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 127 %
|
Millipore
|
LITERATURE.
|
23398362
|
Residual Activity (binding)
|
= 128 %
|
Millipore: Percentage of residual kinase activity of RPS6KA6 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 128 %
|
Millipore: Percentage of residual kinase activity of MAPKAPK5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Na-?-glycerophosphate pH 7.5, 0.1 mM EGTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 130 %
|
Millipore: Percentage of residual kinase activity of CDC42BPA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA
|
ChEMBL.
|
23398362
|
Residual Activity (binding)
|
= 136 %
|
Millipore: Percentage of residual kinase activity of TEK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.5 mM MnCl2
|
ChEMBL.
|
23398362
|
Thermal melting change (binding)
|
|
Delta TM value showing the stabilisation of VRK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
|
Delta TM value showing the stabilisation of YSK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
|
Delta TM value showing the stabilisation of PBK produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
|
Delta TM value showing the stabilisation of VRK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= -0.9 degrees C
|
Delta TM value showing the stabilisation of PAK6 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= -0.7 degrees C
|
Delta TM value showing the stabilisation of PIM3 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0 degrees C
|
Delta TM value showing the stabilisation of CDK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.2 degrees C
|
Delta TM value showing the stabilisation of CAMK2G produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.2 degrees C
|
Delta TM value showing the stabilisation of MAP2K6 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.2 degrees C
|
Delta TM value showing the stabilisation of ASK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.2 degrees C
|
Delta TM value showing the stabilisation of TNIK produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.3 degrees C
|
Delta TM value showing the stabilisation of CAMK2A produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.4 degrees C
|
Delta TM value showing the stabilisation of NDR1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.6 degrees C
|
Delta TM value showing the stabilisation of CAMK2D produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.6 degrees C
|
Delta TM value showing the stabilisation of CLK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.6 degrees C
|
Delta TM value showing the stabilisation of CLK3 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.7 degrees C
|
Delta TM value showing the stabilisation of CAMK4 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.7 degrees C
|
Delta TM value showing the stabilisation of CK1G1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.7 degrees C
|
Delta TM value showing the stabilisation of MST4 (2) produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.8 degrees C
|
Delta TM value showing the stabilisation of CDK6 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.8 degrees C
|
Delta TM value showing the stabilisation of MEK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.8 degrees C
|
Delta TM value showing the stabilisation of p38beta produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.9 degrees C
|
Delta TM value showing the stabilisation of ERK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 0.9 degrees C
|
Delta TM value showing the stabilisation of MST1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1 degrees C
|
Delta TM value showing the stabilisation of CAMK2B produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1 degrees C
|
Delta TM value showing the stabilisation of LOK produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.1 degrees C
|
Delta TM value showing the stabilisation of GSK3B produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.2 degrees C
|
Delta TM value showing the stabilisation of OSR1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.3 degrees C
|
Delta TM value showing the stabilisation of NEK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.3 degrees C
|
Delta TM value showing the stabilisation of PRKACA produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.5 degrees C
|
Delta TM value showing the stabilisation of AMPKA2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.5 degrees C
|
Delta TM value showing the stabilisation of MST4(1) produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.5 degrees C
|
Delta TM value showing the stabilisation of PAK4 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.5 degrees C
|
Delta TM value showing the stabilisation of DRAK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.6 degrees C
|
Delta TM value showing the stabilisation of CDKL1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.6 degrees C
|
Delta TM value showing the stabilisation of PDK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.7 degrees C
|
Delta TM value showing the stabilisation of NEK6 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.8 degrees C
|
Delta TM value showing the stabilisation of ERK3 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 1.9 degrees C
|
Delta TM value showing the stabilisation of CLK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2 degrees C
|
Delta TM value showing the stabilisation of CAMKK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.2 degrees C
|
Delta TM value showing the stabilisation of CK1G3 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.2 degrees C
|
Delta TM value showing the stabilisation of PLK4 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.3 degrees C
|
Delta TM value showing the stabilisation of MPSK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.6 degrees C
|
Delta TM value showing the stabilisation of JAK1~B produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.6 degrees C
|
Delta TM value showing the stabilisation of PAK5 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 2.8 degrees C
|
Delta TM value showing the stabilisation of CAMK1D produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 3.2 degrees C
|
Delta TM value showing the stabilisation of PCTK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 3.3 degrees C
|
Delta TM value showing the stabilisation of PLK1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 3.7 degrees C
|
Delta TM value showing the stabilisation of RIOK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 3.8 degrees C
|
Delta TM value showing the stabilisation of CAMK1G produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 3.8 degrees C
|
Delta TM value showing the stabilisation of CHEK2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 4.1 degrees C
|
Delta TM value showing the stabilisation of SLK produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 4.8 degrees C
|
Delta TM value showing the stabilisation of RSK2a produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 5.7 degrees C
|
Delta TM value showing the stabilisation of RSK2b produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 6.5 degrees C
|
Delta TM value showing the stabilisation of CK1G2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 6.5 degrees C
|
Delta TM value showing the stabilisation of DAPK3 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 6.9 degrees C
|
Delta TM value showing the stabilisation of PIM2 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 7.3 degrees C
|
Delta TM value showing the stabilisation of PIM1 produced by compound binding
|
ChEMBL.
|
18077363
|
Thermal melting change (binding)
|
= 9.3 degrees C
|
Delta TM value showing the stabilisation of DMPK1 produced by compound binding
|
ChEMBL.
|
18077363
|