Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | potassium voltage-gated channel, shaker-related subfamily, member 5 | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Echinococcus multilocularis | voltage gated potassium channel | potassium voltage-gated channel, shaker-related subfamily, member 5 | 613 aa | 521 aa | 34.9 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | animal heme peroxidase | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0531 | 0.1403 | 0.139 |
Brugia malayi | hypothetical protein | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0531 | 0.1403 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | 0.2581 | 0.8073 | 1 | |
Brugia malayi | Blistered cuticle protein 3 | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | peroxidasin | 0.2581 | 0.8073 | 0.807 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus multilocularis | peroxidasin | 0.2581 | 0.8073 | 0.8073 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Brugia malayi | hypothetical protein | 0.0531 | 0.1403 | 0.1723 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0531 | 0.1403 | 0.1403 |
Loa Loa (eye worm) | hypothetical protein | 0.0531 | 0.1403 | 0.1723 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus multilocularis | RUN | 0.0531 | 0.1403 | 0.1403 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0531 | 0.1403 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus granulosus | RUN | 0.0531 | 0.1403 | 0.139 |
Onchocerca volvulus | 0.2581 | 0.8073 | 1 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.3174 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0531 | 0.1403 | 0.1723 |
Brugia malayi | Doublecortin family protein | 0.0531 | 0.1403 | 0.1723 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0531 | 0.1403 | 0.1403 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0531 | 0.1403 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus granulosus | peroxidasin | 0.2581 | 0.8073 | 0.807 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0531 | 0.1403 | 0.139 |
Brugia malayi | Animal haem peroxidase family protein | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | lipoxygenase | 0.3174 | 1 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0531 | 0.1403 | 0.139 |
Brugia malayi | Animal haem peroxidase family protein | 0.2581 | 0.8073 | 1 |
Onchocerca volvulus | 0.2581 | 0.8073 | 1 | |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0531 | 0.1403 | 0.5 |
Brugia malayi | Peroxidasin | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | peroxidasin | 0.2581 | 0.8073 | 0.807 |
Onchocerca volvulus | Peroxidasin homolog | 0.2581 | 0.8073 | 1 |
Brugia malayi | hypothetical protein | 0.0531 | 0.1403 | 0.1723 |
Brugia malayi | Animal haem peroxidase family protein | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0531 | 0.1403 | 0.139 |
Loa Loa (eye worm) | doublecortin family protein | 0.0531 | 0.1403 | 0.1723 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0531 | 0.1403 | 0.1403 |
Schistosoma mansoni | loxhd1 | 0.0531 | 0.1403 | 0.139 |
Schistosoma mansoni | lipoxygenase | 0.2219 | 0.6894 | 0.6889 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0104 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2581 | 0.8073 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.2581 | 0.8073 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0531 | 0.1403 | 0.139 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.